Marc E. Rothenberg
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American physician-scientist
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Marc E. Rothenberg's Degrees
- PhD Biomedical Engineering Johns Hopkins University
Why Is Marc E. Rothenberg Influential?
(Suggest an Edit or Addition)According to Wikipedia, Marc E. Rothenberg is an American physician-scientist who has made significant contributions to the fields of allergy, gastroenterology, and immunology. He is currently a Professor of Pediatrics, at Cincinnati Children's Hospital Medical Center, and the University of Cincinnati College of Medicine, the Director of the Division of Allergy and Immunology, the Director of the Cincinnati Center for Eosinophilic Disorders, and the principal investigator of the Consortium of Eosinophilic Disease Researchers as part of the Rare Disease Clinical Research Network of the National Institute of Health. Rothenberg's research is focused on eosinophilic gastrointestinal diseases.
Marc E. Rothenberg's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Eosinophilic esophagitis: updated consensus recommendations for children and adults. (2011) (1878)
- Eosinophilic esophagitis in children and adults: a systematic review and consensus recommendations for diagnosis and treatment. (2007) (1537)
- Eosinophilic gastrointestinal disorders (EGID). (2004) (801)
- Eotaxin-3 and a uniquely conserved gene-expression profile in eosinophilic esophagitis. (2006) (786)
- Eosinophils: Biological Properties and Role in Health and Disease (2008) (777)
- Human eotaxin is a specific chemoattractant for eosinophil cells and provides a new mechanism to explain tissue eosinophilia (1996) (718)
- An etiological role for aeroallergens and eosinophils in experimental esophagitis. (2001) (606)
- Updated International Consensus Diagnostic Criteria for Eosinophilic Esophagitis: Proceedings of the AGREE Conference. (2018) (561)
- Targeted Disruption of the Chemokine Eotaxin Partially Reduces Antigen-induced Tissue Eosinophilia (1997) (560)
- A randomized, double-blind, placebo-controlled trial of fluticasone propionate for pediatric eosinophilic esophagitis. (2006) (549)
- Treatment of patients with the hypereosinophilic syndrome with mepolizumab. (2008) (520)
- Human eosinophils have prolonged survival, enhanced functional properties, and become hypodense when exposed to human interleukin 3. (1988) (518)
- Dissection of experimental asthma with DNA microarray analysis identifies arginase in asthma pathogenesis. (2003) (506)
- Hypereosinophilic syndrome: a multicenter, retrospective analysis of clinical characteristics and response to therapy. (2009) (465)
- MicroRNA-21 Is Up-Regulated in Allergic Airway Inflammation and Regulates IL-12p35 Expression 1 (2009) (457)
- The eosinophil. (2006) (450)
- Postnatal mammary gland development requires macrophages and eosinophils. (2000) (430)
- Reslizumab in children and adolescents with eosinophilic esophagitis: results of a double-blind, randomized, placebo-controlled trial. (2012) (419)
- Regulation of human eosinophil viability, density, and function by granulocyte/macrophage colony-stimulating factor in the presence of 3T3 fibroblasts (1987) (413)
- Anti-IL-5 (mepolizumab) therapy for eosinophilic esophagitis. (2006) (394)
- Common variants at 5q22 associate with pediatric eosinophilic esophagitis (2010) (393)
- Expression of eotaxin by human lung epithelial cells: induction by cytokines and inhibition by glucocorticoids. (1997) (389)
- Targeting eosinophils in allergy, inflammation and beyond (2013) (383)
- IL-13 involvement in eosinophilic esophagitis: transcriptome analysis and reversibility with glucocorticoids. (2007) (382)
- Fundamental signals that regulate eosinophil homing to the gastrointestinal tract. (1999) (381)
- Mast cells are required for experimental oral allergen-induced diarrhea. (2003) (364)
- Murine eotaxin: an eosinophil chemoattractant inducible in endothelial cells and in interleukin 4-induced tumor suppression. (1995) (364)
- Anti-interleukin-5 (mepolizumab) therapy for hypereosinophilic syndromes. (2004) (360)
- Chemokines in asthma: cooperative interaction between chemokines and IL-13. (2003) (350)
- Intratracheal IL-13 induces eosinophilic esophagitis by an IL-5, eotaxin-1, and STAT6-dependent mechanism. (2003) (347)
- Approaches to the treatment of hypereosinophilic syndromes: a workshop summary report. (2006) (339)
- MicroRNA-21 Limits In Vivo Immune Response-Mediated Activation of the IL-12/IFN-γ Pathway, Th1 Polarization, and the Severity of Delayed-Type Hypersensitivity (2011) (330)
- IL-5 Promotes Eosinophil Trafficking to the Esophagus1 (2002) (322)
- Human monocyte chemoattractant protein (MCP)-4 is a novel CC chemokine with activities on monocytes, eosinophils, and basophils induced in allergic and nonallergic inflammation that signals through the CC chemokine receptors (CCR)-2 and -3. (1996) (320)
- Pediatric patients with eosinophilic esophagitis: an 8-year follow-up. (2007) (312)
- IL-13 induces eosinophil recruitment into the lung by an IL-5- and eotaxin-dependent mechanism. (2001) (309)
- IL-5-dependent conversion of normodense human eosinophils to the hypodense phenotype uses 3T3 fibroblasts for enhanced viability, accelerated hypodensity, and sustained antibody-dependent cytotoxicity. (1989) (301)
- Biology of the eosinophil. (2009) (294)
- A pathological function for eotaxin and eosinophils in eosinophilic gastrointestinal inflammation (2001) (292)
- Importance of Cytokines in Murine Allergic Airway Disease and Human Asthma (2010) (291)
- Refining the definition of hypereosinophilic syndrome. (2010) (287)
- Eotaxin is required for the baseline level of tissue eosinophils. (1998) (287)
- Intrinsic Defect in T Cell Production of Interleukin (IL)-13 in the Absence of Both IL-5 and Eotaxin Precludes the Development of Eosinophilia and Airways Hyperreactivity in Experimental Asthma (2002) (283)
- Biology and treatment of eosinophilic esophagitis. (2009) (276)
- Clinical and immunopathologic effects of swallowed fluticasone for eosinophilic esophagitis. (2004) (271)
- Foxa2 regulates alveolarization and goblet cell hyperplasia (2004) (268)
- Proton pump inhibitor-responsive oesophageal eosinophilia: an entity challenging current diagnostic criteria for eosinophilic oesophagitis (2015) (265)
- Intestinal epithelial cell secretion of RELM-β protects against gastrointestinal worm infection (2009) (263)
- Eosinophil responses during COVID-19 infections and coronavirus vaccination (2020) (260)
- Periostin facilitates eosinophil tissue infiltration in allergic lung and esophageal responses (2008) (256)
- Coordinate Interaction between IL-13 and Epithelial Differentiation Cluster Genes in Eosinophilic Esophagitis (2010) (255)
- IL-9– and mast cell–mediated intestinal permeability predisposes to oral antigen hypersensitivity (2008) (255)
- Distinct roles for IL-13 and IL-4 via IL-13 receptor α1 and the type II IL-4 receptor in asthma pathogenesis (2008) (248)
- Intravenous anti-IL-13 mAb QAX576 for the treatment of eosinophilic esophagitis. (2015) (247)
- Quantity and Distribution of Eosinophils in the Gastrointestinal Tract of Children (2006) (247)
- Involvement of mast cells in eosinophilic esophagitis. (2010) (245)
- The Eotaxin Chemokines and CCR3 Are Fundamental Regulators of Allergen-Induced Pulmonary Eosinophilia1 (2005) (242)
- Variants of thymic stromal lymphopoietin and its receptor associate with eosinophilic esophagitis. (2010) (241)
- Esophageal remodeling develops as a consequence of tissue specific IL-5-induced eosinophilia. (2008) (241)
- Newly developed and validated eosinophilic esophagitis histology scoring system and evidence that it outperforms peak eosinophil count for disease diagnosis and monitoring. (2016) (234)
- Elemental signals regulating eosinophil accumulation in the lung (2001) (232)
- A striking local esophageal cytokine expression profile in eosinophilic esophagitis. (2011) (232)
- Pathogenesis and clinical features of eosinophilic esophagitis. (2001) (231)
- Genome-wide association analysis of eosinophilic esophagitis provides insight into the tissue specificity of this allergic disease (2014) (230)
- Immunotherapy of Cytotoxic T Cell–resistant Tumors by T Helper 2 Cells (2003) (230)
- Interleukin 5 and phenotypically altered eosinophils in the blood of patients with the idiopathic hypereosinophilic syndrome (1989) (228)
- Efficacy of Dupilumab in a Phase 2 Randomized Trial of Adults With Active Eosinophilic Esophagitis. (2019) (222)
- Transgenic expression of bean alpha-amylase inhibitor in peas results in altered structure and immunogenicity. (2005) (221)
- CCR3 is a target for age-related macular degeneration diagnosis and therapy (2009) (219)
- Interleukin-4 Receptor α Signaling in Myeloid Cells Controls Collagen Fibril Assembly in Skin Repair. (2015) (218)
- Health-related quality of life across pediatric chronic conditions. (2010) (212)
- Elevated basal serum tryptase identifies a multisystem disorder associated with increased TPSAB1 copy number (2016) (211)
- Constitutive and allergen-induced expression of eotaxin mRNA in the guinea pig lung (1995) (211)
- Molecular mechanisms of anaphylaxis: lessons from studies with murine models. (2005) (210)
- Molecular diagnosis of eosinophilic esophagitis by gene expression profiling. (2013) (203)
- A central regulatory role for eosinophils and the eotaxin/CCR3 axis in chronic experimental allergic airway inflammation (2006) (200)
- Eotaxin Triggers Eosmophil-Selective Chemotaxis and Calcium Flux via a Distinct Receptor and Induces Pulmonary Eosinophilia in the Presence of Interleukin 5 in Mice (1996) (199)
- Transcriptome analysis of proton pump inhibitor-responsive esophageal eosinophilia reveals proton pump inhibitor-reversible allergic inflammation. (2015) (198)
- Epicutaneous antigen exposure primes for experimental eosinophilic esophagitis in mice. (2005) (195)
- Eosinophils and Cancer (2014) (195)
- Dissociation Between Symptoms and Histological Severity in Pediatric Eosinophilic Esophagitis (2009) (194)
- Twin and family studies reveal strong environmental and weaker genetic cues explaining heritability of eosinophilic esophagitis. (2014) (192)
- Eosinophilic esophagitis: pathogenesis, genetics, and therapy. (2006) (190)
- Local B cells and IgE production in the oesophageal mucosa in eosinophilic oesophagitis (2009) (190)
- Comparative dietary therapy effectiveness in remission of pediatric eosinophilic esophagitis. (2012) (189)
- Efficacy, dose reduction, and resistance to high-dose fluticasone in patients with eosinophilic esophagitis. (2014) (186)
- Diagnostic, functional, and therapeutic roles of microRNA in allergic diseases. (2013) (183)
- Molecular, genetic, and cellular bases for treating eosinophilic esophagitis. (2015) (181)
- Murine Eotaxin-2: A Constitutive Eosinophil Chemokine Induced by Allergen Challenge and IL-4 Overexpression1 (2000) (180)
- Pathophysiology of Eosinophilic Esophagitis. (2017) (180)
- Eosinophil-associated gastrointestinal disorders: a world-wide-web based registry. (2002) (179)
- Potential of blood eosinophils, eosinophil-derived neurotoxin, and eotaxin-3 as biomarkers of eosinophilic esophagitis. (2006) (179)
- The Effect of IL-5 and Eotaxin Expression in the Lung on Eosinophil Trafficking and Degranulation and the Induction of Bronchial Hyperreactivity1 (2000) (176)
- Eotaxin. An essential mediator of eosinophil trafficking into mucosal tissues. (1999) (176)
- IL-13 Induces Esophageal Remodeling and Gene Expression by an Eosinophil-Independent, IL-13Rα2–Inhibited Pathway (2010) (175)
- A critical role for eotaxin in experimental oral antigen-induced eosinophilic gastrointestinal allergy. (2000) (175)
- Interleukin-13 mediates airways hyperreactivity through the IL-4 receptor-alpha chain and STAT-6 independently of IL-5 and eotaxin. (2001) (173)
- Regulation of Carcinogenesis by IL-5 and CCL11: A Potential Role for Eosinophils in Tumor Immune Surveillance1 (2007) (171)
- Eosinophilic esophagitis is characterized by a non‐IgE‐mediated food hypersensitivity (2016) (169)
- Inhibition of human interleukin‐13‐induced respiratory and oesophageal inflammation by anti‐human‐interleukin‐13 antibody (CAT‐354) (2005) (169)
- Molecular and Biological Characterization of the Murine Leukotriene B4 Receptor Expressed on Eosinophils (1998) (168)
- Defective T cell development and function in calcineurin Aβ-deficient mice (2002) (167)
- Induction of Interleukin-9-Producing Mucosal Mast Cells Promotes Susceptibility to IgE-Mediated Experimental Food Allergy. (2015) (164)
- Resistin-like molecule beta regulates innate colonic function: barrier integrity and inflammation susceptibility. (2006) (163)
- Role of the monocyte chemoattractant protein and eotaxin subfamily of chemokines in allergic inflammation (1997) (160)
- Identification of a Cooperative Mechanism Involving Interleukin-13 and Eotaxin-2 in Experimental Allergic Lung Inflammation* (2005) (154)
- Intestinal Macrophage/Epithelial Cell-Derived CCL11/Eotaxin-1 Mediates Eosinophil Recruitment and Function in Pediatric Ulcerative Colitis1 (2008) (149)
- CC Chemokine Receptor-3 Undergoes Prolonged Ligand-induced Internalization* (1999) (147)
- Long-term safety of mepolizumab for the treatment of hypereosinophilic syndromes. (2013) (144)
- Eosinophilic esophagitis. (2004) (143)
- Eosinophils in mucosal immune responses (2015) (142)
- MicroRNA signature in patients with eosinophilic esophagitis, reversibility with glucocorticoids, and assessment as disease biomarkers. (2012) (142)
- RPC4046, a Monoclonal Antibody Against IL13, Reduces Histologic and Endoscopic Activity in Patients With Eosinophilic Esophagitis. (2019) (141)
- High prevalence of eosinophilic esophagitis in patients with inherited connective tissue disorders. (2013) (139)
- Anti-IL-5 (mepolizumab) therapy reduces eosinophil activation ex vivo and increases IL-5 and IL-5 receptor levels. (2008) (136)
- The R576 IL-4 receptor α allele correlates with asthma severity☆☆☆★ (1999) (133)
- Siglec‐F antibody administration to mice selectively reduces blood and tissue eosinophils (2008) (130)
- The Regulatory Function of Eosinophils. (2016) (130)
- Long-term outcomes in pediatric-onset esophageal eosinophilia. (2011) (129)
- Prevalence and Outcome of Allergic Colitis in Healthy Infants with Rectal Bleeding: A Prospective Cohort Study (2005) (129)
- The E3 ubiquitin ligase midline 1 promotes allergen and rhinovirus-induced asthma by inhibiting protein phosphatase 2A activity (2013) (129)
- Modulatory calcineurin-interacting proteins 1 and 2 function as calcineurin facilitators in vivo. (2006) (127)
- Arginase I Suppresses IL-12/IL-23p40–Driven Intestinal Inflammation during Acute Schistosomiasis (2010) (127)
- Liver microRNA-21 is overexpressed in non-alcoholic steatohepatitis and contributes to the disease in experimental models by inhibiting PPARα expression (2015) (126)
- Eosinophils cocultured with endothelial cells have increased survival and functional properties. (1987) (125)
- Transcript Signatures in Experimental Asthma: Identification of STAT6-Dependent and -Independent Pathways1 (2004) (122)
- Gastrointestinal eosinophils (2001) (122)
- Pulmonary Chemokine Expression Is Coordinately Regulated by STAT1, STAT6, and IFN-γ (2004) (121)
- Genetic dissection of eosinophilic esophagitis provides insight into disease pathogenesis and treatment strategies. (2011) (120)
- Eotaxin-2 and IL-5 cooperate in the lung to regulate IL-13 production and airway eosinophilia and hyperreactivity. (2003) (118)
- Identification, epidemiology, and chronicity of pediatric esophageal eosinophilia, 1982-1999. (2010) (115)
- T cell–intrinsic ASC critically promotes TH17-mediated experimental autoimmune encephalomyelitis (2016) (114)
- Interplay of Adaptive Th2 Immunity with Eotaxin-3/C-C Chemokine Receptor 3 in Eosinophilic Esophagitis (2007) (112)
- Histologic eosinophilic gastritis is a systemic disorder associated with blood and extragastric eosinophilia, TH2 immunity, and a unique gastric transcriptome. (2014) (109)
- Negative regulation of eosinophil recruitment to the lung by the chemokine monokine induced by IFN-γ (Mig, CXCL9) (2004) (108)
- Roles and Regulation of Gastrointestinal Eosinophils in Immunity and Disease (2014) (108)
- Gastrointestinal eosinophils in health and disease. (2001) (108)
- IL-25 and CD4(+) TH2 cells enhance type 2 innate lymphoid cell-derived IL-13 production, which promotes IgE-mediated experimental food allergy. (2016) (107)
- Expression and regulation of a disintegrin and metalloproteinase (ADAM) 8 in experimental asthma. (2004) (106)
- IL-17E upregulates the expression of proinflammatory cytokines in lung fibroblasts. (2006) (106)
- Pediatric Eosinophilic Esophagitis Symptom Scores (PEESS v2.0) identify histologic and molecular correlates of the key clinical features of disease. (2015) (106)
- Advances in mechanisms of asthma, allergy, and immunology in 2010. (2011) (105)
- Formation and stability of ring-substituted 1-phenylethyl carbocations (1984) (105)
- Eosinophilic esophagitis-linked calpain 14 is an IL-13-induced protease that mediates esophageal epithelial barrier impairment. (2016) (105)
- Persistent effects induced by IL-13 in the lung. (2006) (104)
- Anti-Siglec-8 Antibody for Eosinophilic Gastritis and Duodenitis. (2020) (104)
- Basic pathogenesis of eosinophilic esophagitis. (2008) (102)
- Colonic Eosinophilic Inflammation in Experimental Colitis Is Mediated by Ly6Chigh CCR2+ Inflammatory Monocyte/Macrophage-Derived CCL11 (2011) (99)
- Analysis and expansion of the eosinophilic esophagitis transcriptome by RNA sequencing (2014) (97)
- Enterocyte Expression of the Eotaxin and Interleukin-5 Transgenes Induces Compartmentalized Dysregulation of Eosinophil Trafficking* (2002) (95)
- Defective T cell development and function in calcineurin A beta -deficient mice. (2002) (95)
- Esophageal Organoids from Human Pluripotent Stem Cells Delineate Sox2 Functions during Esophageal Specification. (2018) (94)
- Inhibition of Arginase I Activity by RNA Interference Attenuates IL-13-Induced Airways Hyperresponsiveness1 (2006) (94)
- Novel targeted therapies for eosinophilic disorders. (2012) (93)
- Molecular characterization of two murine eosinophil beta chemokine receptors. (1995) (93)
- Mendelian inheritance of elevated serum tryptase associated with atopy and connective tissue abnormalities. (2014) (93)
- Influence of cigarette smoke on the arginine pathway in asthmatic airways: increased expression of arginase I. (2007) (92)
- Clinical, pathologic, and molecular characterization of familial eosinophilic esophagitis compared with sporadic cases. (2008) (90)
- The FIP1L1-PDGFRA fusion gene cooperates with IL-5 to induce murine hypereosinophilic syndrome (HES)/chronic eosinophilic leukemia (CEL)-like disease. (2006) (90)
- Eosinophilic oesophagitis endotype classification by molecular, clinical, and histopathological analyses: a cross-sectional study. (2018) (90)
- Interleukin-15 expression is increased in human eosinophilic esophagitis and mediates pathogenesis in mice. (2010) (90)
- Critical role for adaptive T cell immunity in experimental eosinophilic esophagitis in mice (2007) (88)
- Characterization of a human eosinophil proteoglycan, and augmentation of its biosynthesis and size by interleukin 3, interleukin 5, and granulocyte/macrophage colony stimulating factor. (1988) (88)
- Single-cell RNA sequencing identifies inflammatory tissue T cells in eosinophilic esophagitis. (2019) (87)
- Epicutaneous aeroallergen exposure induces systemic TH2 immunity that predisposes to allergic nasal responses. (2006) (85)
- Identification of a mouse eosinophil receptor for the CC chemokine eotaxin. (1996) (85)
- Eosinophil viability is increased by acidic pH in a cAMP- and GPR65-dependent manner. (2009) (85)
- Eosinophils and CCR3 regulate interleukin-13 transgene-induced pulmonary remodeling. (2006) (85)
- PedsQL Eosinophilic Esophagitis Module: Feasibility, Reliability, and Validity (2013) (84)
- Indoor insect allergens are potent inducers of experimental eosinophilic esophagitis in mice (2010) (84)
- Organ-specific eosinophilic disorders of the skin, lung, and gastrointestinal tract. (2010) (83)
- Development of a validated patient-reported symptom metric for pediatric Eosinophilic Esophagitis: qualitative methods (2011) (83)
- A murine model of allergic rhinitis: studies on the role of IgE in pathogenesis and analysis of the eosinophil influx elicited by allergen and eotaxin. (1998) (82)
- IL-33 Markedly Activates Murine Eosinophils by an NF-κB–Dependent Mechanism Differentially Dependent upon an IL-4–Driven Autoinflammatory Loop (2013) (81)
- Arginine in asthma and lung inflammation. (2004) (80)
- Receptor internalization is required for eotaxin-induced responses in human eosinophils. (2003) (79)
- Chemokines and Chemokine Receptors: Their Role in Allergic Airway Disease (1999) (79)
- Recombinant human FIZZ3/resistin stimulates lipolysis in cultured human adipocytes, mouse adipose explants, and normal mice. (2005) (79)
- The arginine-arginase balance in asthma and lung inflammation. (2006) (78)
- Phenome-wide association study (PheWAS) in EMR-linked pediatric cohorts, genetically links PLCL1 to speech language development and IL5-IL13 to Eosinophilic Esophagitis (2014) (76)
- Prenatal, intrapartum, and postnatal factors are associated with pediatric eosinophilic esophagitis (2018) (74)
- Crosstalk between Gi and Gq/Gs pathways in airway smooth muscle regulates bronchial contractility and relaxation. (2007) (73)
- miR-223 Deficiency Increases Eosinophil Progenitor Proliferation (2013) (72)
- Glucocorticoid-regulated genes in eosinophilic esophagitis: a role for FKBP51. (2010) (72)
- Calpain-14 and its association with eosinophilic esophagitis. (2017) (72)
- Resistin-like molecule alpha enhances myeloid cell activation and promotes colitis. (2008) (72)
- Differences in Candidate Gene Association between European Ancestry and African American Asthmatic Children (2011) (71)
- Gastrointestinal eosinophilia. (2007) (70)
- IL-5 Triggers a Cooperative Cytokine Network That Promotes Eosinophil Precursor Maturation (2014) (69)
- Resistin-like molecule-beta is an allergen-induced cytokine with inflammatory and remodeling activity in the murine lung. (2007) (69)
- Expression and regulation of small proline-rich protein 2 in allergic inflammation. (2005) (68)
- Critical role for adaptive T cell immunity in experimental eosinophilic esophagitis in mice. (2007) (68)
- Genomic organization, complete sequence, and chromosomal location of the gene for human eotaxin (SCYA11), an eosinophil-specific CC chemokine. (1997) (67)
- Eosinophilic esophagitis: rapidly advancing insights. (2012) (66)
- Chromatin regulates IL-33 release and extracellular cytokine activity (2018) (65)
- CD48 Is an Allergen and IL-3-Induced Activation Molecule on Eosinophils1 (2006) (64)
- Allergy and eosinophil-associated gastrointestinal disorders (EGID). (2008) (63)
- The role of Th2 cytokines, chemokines and parasite products in eosinophil recruitment to the gastrointestinal mucosa during helminth infection (2006) (63)
- Quality of life in paediatric eosinophilic oesophagitis: what is important to patients? (2012) (62)
- Targeting IL-4/IL-13 signaling to alleviate oral allergen-induced diarrhea. (2009) (62)
- Early‐life environmental exposures interact with genetic susceptibility variants in pediatric patients with eosinophilic esophagitis (2018) (61)
- Efficacy and safety of mepolizumab in hypereosinophilic syndrome: A phase III, randomized, placebo-controlled trial (2020) (61)
- Mechanisms of Disease of Eosinophilic Esophagitis. (2016) (61)
- Gastrointestinal eosinophils (2001) (61)
- A dual activation and inhibition role for the paired immunoglobulin-like receptor B in eosinophils. (2008) (61)
- Leveraging Multilayered “Omics” Data for Atopic Dermatitis: A Road Map to Precision Medicine (2018) (61)
- The R576 IL-4 receptor alpha allele correlates with asthma severity. (1999) (60)
- Alpha 1 Antitrypsin is an Inhibitor of the SARS-CoV-2-Priming Protease TMPRSS2 (2020) (59)
- Phenotypic Characterization of Eosinophilic Esophagitis in a Large Multicenter Patient Population from the Consortium for Food Allergy Research. (2018) (58)
- Abnormal response to stress and impaired NPS-induced hyperlocomotion, anxiolytic effect and corticosterone increase in mice lacking NPSR1 (2010) (58)
- The α4bβ7‐integrin is dynamically expressed on murine eosinophils and involved in eosinophil trafficking to the intestine (2006) (57)
- Interleukin-5-mediated Allergic Airway Inflammation Inhibits the Human Surfactant Protein C Promoter in Transgenic Mice* (2001) (57)
- Surfactant protein D alters allergic lung responses in mice and human subjects. (2008) (56)
- The antiprotease SPINK7 serves as an inhibitory checkpoint for esophageal epithelial inflammatory responses (2018) (56)
- Trefoil factor-2 is an allergen-induced gene regulated by Th2 cytokines and STAT6 in the lung. (2003) (56)
- Increasing Rates of Diagnosis, Substantial Co-occurrence, and Variable Treatment Patterns of Eosinophilic Gastritis, Gastroenteritis and Colitis Based on 10 Year Data Across a Multi-Center Consortium (2018) (55)
- Eosinophil function in eosinophil-associated gastrointestinal disorders (2006) (55)
- The management of eosinophilic esophagitis. (2013) (54)
- ERBIN deficiency links STAT3 and TGF-β pathway defects with atopy in humans (2017) (54)
- Interleukin-13 (IL-13)/IL-13 Receptor α1 (IL-13Rα1) Signaling Regulates Intestinal Epithelial Cystic Fibrosis Transmembrane Conductance Regulator Channel-dependent Cl− Secretion* (2011) (53)
- A Plant-Based Allergy Vaccine Suppresses Experimental Asthma Via an IFN-γ and CD4+CD45RBlow T Cell-Dependent Mechanism (2003) (53)
- Suppressive Effect of IL-4 on IL-13-Induced Genes in Mouse Lung1 (2005) (53)
- Paired immunoglobulin-like receptor A is an intrinsic, self-limiting suppressor of IL-5-induced eosinophil development (2013) (52)
- ICAM‐1‐dependent pathways regulate colonic eosinophilic inflammation (2006) (52)
- Peyer's patch eosinophils: identification, characterization, and regulation by mucosal allergen exposure, interleukin-5, and eotaxin. (2000) (51)
- Polymorphisms in the sialic acid-binding immunoglobulin-like lectin-8 (Siglec-8) gene are associated with susceptibility to asthma (2010) (51)
- Workshop report from the National Institutes of Health Taskforce on the Research Needs of Eosinophil-Associated Diseases (TREAD). (2012) (50)
- Cationic amino acid transporter 2 regulates inflammatory homeostasis in the lung (2006) (50)
- Eotaxin‐1‐regulated eosinophils have a critical role in innate immunity against experimental Brugia malayi infection (2005) (49)
- Paired immunoglobulin-like receptor B (PIR-B) negatively regulates macrophage activation in experimental colitis. (2010) (48)
- The Pan-B Cell Marker CD22 Is Expressed on Gastrointestinal Eosinophils and Negatively Regulates Tissue Eosinophilia (2012) (48)
- Resolving the etiology of atopic disorders by using genetic analysis of racial ancestry. (2016) (48)
- Rab5 Is a Novel Regulator of Mast Cell Secretory Granules: Impact on Size, Cargo, and Exocytosis (2014) (48)
- Genetics of eosinophilic esophagitis (2017) (48)
- Rank-based genome-wide analysis reveals the association of Ryanodine receptor-2 gene variants with childhood asthma among human populations (2013) (48)
- Targeted Ablation of miR-21 Decreases Murine Eosinophil Progenitor Cell Growth (2013) (48)
- Eosinophil adoptive transfer system to directly evaluate pulmonary eosinophil trafficking in vivo (2013) (48)
- Profound loss of esophageal tissue differentiation in patients with eosinophilic esophagitis (2017) (47)
- Molecular analysis of human Siglec-8 orthologs relevant to mouse eosinophils: identification of mouse orthologs of Siglec-5 (mSiglec-F) and Siglec-10 (mSiglec-G). (2003) (46)
- CXCL9 inhibits eosinophil responses by a CCR3- and Rac2-dependent mechanism. (2005) (46)
- Esophageal IgG4 levels correlate with histopathologic and transcriptomic features in eosinophilic esophagitis (2018) (46)
- CD48 is critically involved in allergic eosinophilic airway inflammation. (2007) (45)
- Eosinophil depletion suppresses radiation-induced small intestinal fibrosis (2018) (45)
- Resistin-Like Molecule α Decreases Glucose Tolerance during Intestinal Inflammation1 (2009) (44)
- Clinical reviews in allergy and immunology (2012) (44)
- A morphometric study of normodense and hypodense human eosinophils that are derived in vivo and in vitro. (1990) (44)
- Polymorphisms in the human CC chemokine receptor-3 gene. (1998) (43)
- Working with the US Food and Drug Administration: progress and timelines in understanding and treating patients with eosinophilic esophagitis. (2012) (43)
- IL-13Rα2 Has a Protective Role in a Mouse Model of Cutaneous Inflammation (2010) (42)
- Building a better mouse model: experimental models of chronic asthma (2005) (42)
- Molecular Analysis of CCR-3 Events in Eosinophilic Cells1 (2000) (42)
- Epithelial origin of eosinophilic esophagitis (2018) (42)
- Eosinophil Knockout Humans: Uncovering the Role of Eosinophils Through Eosinophil-Directed Biological Therapies. (2021) (42)
- Development of the Pediatric Quality of Life Inventory™ Eosinophilic Esophagitis Module items: qualitative methods (2012) (41)
- Molecular mechanism of inhibiting the SARS-CoV-2 cell entry facilitator TMPRSS2 with camostat and nafamostat (2020) (39)
- Cellular and molecular regulation of eosinophil trafficking to the lung (1998) (39)
- Resistin-like molecule-α regulates IL-13-induced chemokine production but not allergen-induced airway responses. (2012) (39)
- Epigenetic Regulation of the IL-13-induced Human Eotaxin-3 Gene by CREB-binding Protein-mediated Histone 3 Acetylation* (2011) (39)
- Neurotrophic tyrosine kinase receptor 1 is a direct transcriptional and epigenetic target of IL-13 involved in allergic inflammation (2014) (38)
- Anti-IL-5 and hypereosinophilic syndromes. (2005) (38)
- Eosinophilic esophagitis (EoE) genetic susceptibility is mediated by synergistic interactions between EoE‐specific and general atopic disease loci (2017) (38)
- Alignment of parent‐ and child‐reported outcomes and histology in eosinophilic esophagitis across multiple CEGIR sites (2018) (38)
- A negative, double-blind, placebo-controlled challenge to genetically modified corn. (2003) (37)
- Epithelial cells are a major cellular source of the chemokine eotaxin in the guinea pig lung. (1998) (37)
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- IL-4Rα Expression by Bone Marrow-Derived Cells Is Necessary and Sufficient for Host Protection against Acute Schistosomiasis1 (2008) (36)
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- Tryptase 4, a New Member of the Chromosome 17 Family of Mouse Serine Proteases* (2001) (33)
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- Utility of Neutrophil Fc&ggr; Receptor I (CD64) Index as a Biomarker for Mucosal Inflammation in Pediatric Crohn's Disease (2014) (31)
- Revisiting the NIH Taskforce on the Research needs of Eosinophil‐Associated Diseases (RE‐TREAD) (2018) (31)
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- Association Between Endoscopic and Histologic Findings in a Multicenter Retrospective Cohort of Patients with Non-esophageal Eosinophilic Gastrointestinal Disorders (2019) (29)
- ICON: Eosinophil Disorders (2012) (29)
- Experimental gastrointestinal allergy enhances pulmonary responses to specific and unrelated allergens. (2006) (29)
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- Persistent rotavirus vaccine shedding in a new case of severe combined immunodeficiency: A reason to screen. (2010) (28)
- TNF-related apoptosis-inducing ligand (TRAIL) regulates midline-1, thymic stromal lymphopoietin, inflammation, and remodeling in experimental eosinophilic esophagitis. (2015) (28)
- Behavioral functioning and treatment adherence in pediatric eosinophilic gastrointestinal disorders (2012) (28)
- Bone marrow cell derived arginase I is the major source of allergen-induced lung arginase but is not required for airway hyperresponsiveness, remodeling and lung inflammatory responses in mice (2009) (27)
- Esophageal type 2 cytokine expression heterogeneity in eosinophilic esophagitis in a multi-site cohort. (2020) (27)
- Genetic and epigenetic underpinnings of eosinophilic esophagitis. (2014) (27)
- Rab12 Regulates Retrograde Transport of Mast Cell Secretory Granules by Interacting with the RILP–Dynein Complex (2016) (27)
- Psychological Functioning of Children and Adolescents With Eosinophil-Associated Gastrointestinal Disorders (2010) (27)
- Chemokines in eosinophil-associated gastrointestinal disorders (2004) (27)
- Eosinophilic esophagitis: Concepts, controversies, and evidence (2009) (27)
- The cationic amino acid transporter 2 is induced in inflammatory lung models and regulates lung fibrosis (2010) (26)
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- Origin, regulation and physiological function of intestinal oeosinophils. (2008) (26)
- Analysis of the CCR3 promoter reveals a regulatory region in exon 1 that binds GATA-1 (2005) (26)
- Pulmonary eosinophilia requires interleukin‐5, eotaxin‐1, and CD4+ T cells in mice immunized with respiratory syncytial virus G glycoprotein (2008) (25)
- Intratracheal interleukin-13 induces eosinophilic esophagitis (EE)* (2003) (25)
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- A novel class of TMPRSS2 inhibitors potently block SARS-CoV-2 and MERS-CoV viral entry and protect human epithelial lung cells (2021) (23)
- Alpha 1 Antitrypsin is an Inhibitor of the SARS-CoV-2–Priming Protease TMPRSS2 (2021) (23)
- CD300f:IL-5 cross-talk inhibits adipose tissue eosinophil homing and subsequent IL-4 production (2017) (23)
- Environmental Allergens Trigger Type 2 Inflammation Through Ripoptosome Activation (2021) (23)
- Agonist Activation of F-Actin-Mediated Eosinophil Shape Change and Mediator Release Is Dependent on Rac2 (2011) (23)
- Synaptopodin is upregulated by IL-13 in eosinophilic esophagitis and regulates esophageal epithelial cell motility and barrier integrity. (2017) (23)
- CD44--a sticky target for asthma. (2003) (22)
- T helper-2 immunity regulates bronchial hyperresponsiveness in eosinophil-associated gastrointestinal disease in mice. (2004) (22)
- Acquired coenzyme Q10 deficiency in children with recurrent food intolerance and allergies. (2011) (22)
- An eosinophil hypothesis for functional dyspepsia. (2007) (22)
- Cytotoxic γδ T lymphocytes associated with an Epstein-Barr virus-induced posttransplantation lymphoproliferative disorder (1996) (22)
- Pathogenesis of Disease (2016) (21)
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- IL-33 is induced in undifferentiated, non-dividing esophageal epithelial cells in eosinophilic esophagitis (2017) (21)
- MicroRNA‐21 Ablation Exacerbates Aldosterone‐Mediated Cardiac Injury, Remodeling and Dysfunction (2015) (21)
- Genetic variants at the 16p13 locus confer risk for eosinophilic esophagitis (2018) (20)
- Airway structural alterations selectively associated with severe asthma (2003) (20)
- Metastasis-Entrained Eosinophils Enhance Lymphocyte-Mediated Antitumor Immunity (2021) (20)
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- Constitutive overexpression of IL-5 induces extramedullary hematopoiesis in the spleen. (2003) (20)
- Mechanisms of gastrointestinal allergic disorders. (2019) (20)
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- Molecular mechanism of SARS-CoV-2 cell entry inhibition via TMPRSS2 by Camostat and Nafamostat mesylate (2020) (20)
- Eosinophilic Gastrointestinal Disorders (2016) (19)
- Demethylation of the Human Eotaxin-3 Gene Promoter Leads to the Elevated Expression of Eotaxin-3 (2014) (19)
- Eosinophilic Esophagitis Histology Remission Score: Significant Relations to Measures of Disease Activity and Symptoms. (2020) (19)
- Ontogeny of in vitro-differentiated mouse mast cells. (1987) (19)
- ALLERGEN INDUCED TFF2 IS EXPRESSED BY MUCUS-PRODUCING AIRWAY EPITHELIAL CELLS BUT IS NOT A MAJOR REGULATOR OF INFLAMMATORY RESPONSES IN THE MURINE LUNG (2006) (19)
- Eosinophil progenitor levels are increased in patients with active pediatric eosinophilic esophagitis. (2016) (17)
- International consensus recommendations for eosinophilic gastrointestinal disease nomenclature. (2022) (17)
- Broad transcriptional response of the human esophageal epithelium to proton pump inhibitors. (2020) (17)
- Innate sensing of nickel (2010) (17)
- Disease-Related Predictors of Health-Related Quality of Life in Youth With Eosinophilic Esophagitis (2018) (17)
- FIP1L1/PDGFRalpha synergizes with SCF to induce systemic mastocytosis in a murine model of chronic eosinophilic leukemia/hypereosinophilic syndrome. (2008) (17)
- Development of a core outcome set for therapeutic studies in eosinophilic esophagitis (COREOS) (2021) (17)
- Chemokines in allergic disease (2000) (17)
- Novel immunologic mechanisms in eosinophilic esophagitis. (2017) (16)
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- The role of neuropeptide S and neuropeptide S receptor 1 in regulation of respiratory function in mice (2011) (16)
- The Incidence and Prevalence of Eosinophilic Esophagitis (2008) (15)
- Early life factors are associated with risk for eosinophilic esophagitis diagnosed in adulthood. (2017) (15)
- Resistin-Like Molecule α in Allergen-Induced Pulmonary Vascular Remodeling. (2015) (15)
- A novel class of TMPRSS2 inhibitors potently block SARS-CoV-2 and MERS-CoV viral entry and protect human epithelial lung cells (2021) (15)
- Substantial Variability in Biopsy Practice Patterns Among Gastroenterologists for Suspected Eosinophilic Gastrointestinal Disorders. (2016) (14)
- A novel approach to conducting clinical trials in the community setting: utilizing patient-driven platforms and social media to drive web-based patient recruitment (2019) (14)
- Carbonic Anhydrase IV Is Expressed on IL-5–Activated Murine Eosinophils (2014) (14)
- Transcriptomic Analysis Links Eosinophilic Esophagitis and Atopic Dermatitis (2019) (14)
- Eotaxin-Rich Proangiogenic Hematopoietic Progenitor Cells and CCR3+ Endothelium in the Atopic Asthmatic Response (2016) (14)
- 17β-Estradiol protects the esophageal epithelium from IL-13-induced barrier dysfunction and remodeling. (2019) (14)
- Eosinophil–lymphocyte interactions in the tumor microenvironment and cancer immunotherapy (2022) (14)
- Antigen presentation by eosinophils in eosinophilic esophagitis? (2013) (14)
- Expanding the paradigm of eosinophilic esophagitis: mast cells and IL-9. (2013) (14)
- A hidden residential cell in the lung. (2016) (14)
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- Solute carrier family 9, subfamily A, member 3 (SLC9A3)/sodium‐hydrogen exchanger member 3 (NHE3) dysregulation and dilated intercellular spaces in patients with eosinophilic esophagitis (2018) (13)
- Isolation of immunoreactive β-endorphin-related and Met-enkephalin-related peptides from the posterior pituitary of the amphibian, Xenopus laevis (1987) (13)
- Clinical Applications of the Eosinophilic Esophagitis Diagnostic Panel (2017) (13)
- Replication and meta-analyses nominate numerous eosinophilic esophagitis risk genes. (2020) (13)
- Eosinophil levels in mice are significantly higher in small blood vessels than in large blood vessels. (2001) (13)
- DP1 receptor signaling prevents the onset of intrinsic apoptosis in eosinophils and functions as a transcriptional modulator (2018) (12)
- Remote immune processes revealed by immune-derived circulating cell-free DNA (2021) (12)
- Eosinophils in the new millennium. (2007) (12)
- Machine Learning Approach for Biopsy-Based Identification of Eosinophilic Esophagitis Reveals Importance of Global features (2021) (12)
- Eliminating eosinophilic esophagitis. (2005) (11)
- Loss of Endothelial TSPAN12 Promotes Fibrostenotic Eosinophilic Esophagitis via Endothelial Cell-Fibroblast Crosstalk. (2021) (11)
- Chemotactic factors associated with eosinophilic gastrointestinal diseases. (2009) (11)
- Association of eosinophilic esophagitis and hypertrophic cardiomyopathy. (2016) (11)
- Eosinophil progenitor levels correlate with tissue pathology in pediatric eosinophilic esophagitis. (2019) (11)
- Steroid-Sparing Effects of Anti-IL-5 Monoclonal Antibody (Mepolizumab) Therapy in Patients with HES: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial. (2006) (11)
- Genetic, Inflammatory, and Epithelial Cell Differentiation Factors Control Expression of Human Calpain-14 (2019) (11)
- Single-cell RNA sequencing of mast cells in eosinophilic esophagitis reveals heterogeneity, local proliferation and activation that persists in remission. (2022) (11)
- Linking impaired skin barrier function to esophageal allergic inflammation via IL-33. (2016) (10)
- Dietary allergenic proteins and intestinal immunity: a shift from oral tolerance to sensitization (2007) (10)
- Desmoplakin and periplakin genetically and functionally contribute to eosinophilic esophagitis (2021) (10)
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- EQUILIBRIUM CONSTANTS FOR THE INTERCONVERSION OF SUBSTITUTED 1-PHENYLETHYL ALCOHOLS AND ETHERS. A MEASUREMENT OF INTRAMOLECULAR ELECTROSTATIC INTERACTIONS (1985) (10)
- Cell-by-cell deciphering of T cells in allergic inflammation. (2019) (10)
- Very early onset eosinophilic esophagitis is common, responds to standard therapy, and demonstrates enrichment for CAPN14 genetic variants. (2020) (10)
- Paired Ig-like Receptor B Inhibits IL-13–Driven Eosinophil Accumulation and Activation in the Esophagus (2016) (10)
- New developments in patients with eosinophilic gastrointestinal diseases presented at the CEGIR/TIGERS Symposium at the 2018 American Academy of Allergy, Asthma & Immunology Meeting. (2018) (10)
- Eosinophilic gastrointestinal disease below the belt (2020) (9)
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- Making it big in allergy. (2015) (9)
- Prevalence of eosinophilic colitis and the diagnoses associated with colonic eosinophilia. (2019) (9)
- Eosinophilic esophagitis (2005) (9)
- Investigating mast cell secretory granules; from biosynthesis to exocytosis. (2015) (9)
- Identification of ANO1 as a key driver of esophageal epithelial proliferation in eosinophilic esophagitis. (2019) (9)
- Eosinophilic asthma: insights into the effects of reducing IL-5 receptor-positive cell levels. (2013) (9)
- Determination of Biopsy Yield That Optimally Detects Eosinophilic Gastritis and/or Duodenitis in a Randomized Trial of Lirentelimab. (2021) (9)
- Mitochondrial missile defense (2008) (8)
- Current Concepts on the Pathogenesis of the Hypereosinophilic Syndrome/Chronic Eosinophilic Leukemia (2006) (8)
- Correction: ERBIN deficiency links STAT3 and TGF-β pathway defects with atopy in humans (2017) (8)
- Long-Lasting Dissociation of Esophageal Eosinophilia and Symptoms Following Dilation in Adults with Eosinophilic Esophagitis. (2021) (8)
- Type 2 Immunity and Age Modify Gene Expression of Coronavirus-induced Disease 2019 Receptors in Eosinophilic Gastrointestinal Disorders (2020) (8)
- Cytotoxic gamma delta I lymphocytes associated with an Epstein-Barr virus-induced posttransplantation lymphoproliferative disorder. (1996) (8)
- Epigenetic Regulation Of The Il-13-induced Human Eotaxin-3 Gene By CBP Mediated Histone-3 Acetylation (2011) (8)
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- CXCL 9 inhibits eosinophil responses by a CCR 3-and Rac 2-dependent mechanism (2005) (7)
- Host-microbiota interactions in the esophagus during homeostasis and allergic inflammation. (2021) (7)
- Identification of anoctamin 1 (ANO1) as a key driver of esophageal epithelial proliferation in eosinophilic esophagitis (2020) (7)
- Esophagus IL-5 Promotes Eosinophil Trafficking to the Rothenberg (2002) (7)
- Bidirectional Crosstalk Between Eosinophils and Esophageal Epithelial Cells Regulates Inflammatory and Remodeling Processes (2021) (7)
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- Dupilumab Improves Health-Related Quality of Life (HRQoL) and Reduces Symptom Burden in Patients with Eosinophilic Esophagitis (EoE): Results From Part A of a Randomized, Placebo-Controlled Three-Part Phase 3 Study (2021) (6)
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- Document de consensus WAO–ARIA–GA2LEN sur le diagnostic allergologique moléculaire ☆ (2015) (6)
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- Unsedated Transnasal Esophagoscopy with Virtual Reality Distraction Enables Earlier Monitoring of Dietary Therapy in Eosinophilic Esophagitis. (2021) (6)
- Dupilumab Improves Clinical and Histologic Aspects of Disease in Adult and Adolescent Patients With Eosinophilic Esophagitis at Week 24: Results from Part B of the 3-Part LIBERTY EoE TREET Study (2022) (6)
- Mepolizumab reduces hypereosinophilic syndrome flares irrespective of blood eosinophil count and IL-5. (2022) (6)
- The Climate Change Hypothesis for the Allergy Epidemic. (2022) (6)
- AK002, an Anti-Siglec-8 Antibody, Depletes Tissue Eosinophils and Improves Dysphagia Symptoms in Patients with Eosinophilic Esophagitis (2020) (6)
- Recent advances in eosinophilic esophagitis (2017) (6)
- Murine Model of Hypereosinophilic Syndromes/Chronic Eosinophilic Leukemia (2009) (6)
- Sa1151 - Baseline Characteristics and Correlation Between Dysphagia and Disease Activity in Patients with Eosinophilic Esophagitis in a Randomized, Placebo-Controlled, Phase 2 Dupilumab Trial (2018) (5)
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- Oral antigen-induced intestinal anaphylaxis requires IgE-dependent mast cell degranulation (2003) (5)
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- Targeted IL-4Rα blockade ameliorates refractory allergic eosinophilic inflammation in a patient with dysregulated TGF-β signalling due to ERBIN deficiency. (2022) (4)
- Functional and Phenotypic Characterization of Siglec-6 on Human Mast Cells (2022) (4)
- Uncovering the secretes of allergic inflammation. (2020) (4)
- Diagnostic Merits of Eosinophilic Esophagitis Diagnostic Panel from a Single Esophageal Biopsy. (2021) (4)
- A Deep Multi-Label Segmentation Network For Eosinophilic Esophagitis Whole Slide Biopsy Diagnostics (2022) (4)
- Reply: To PMID 22541246. (2013) (4)
- 2021 Year in Review: Spotlight on Eosinophils. (2021) (4)
- Development and Application of a Functional Human Esophageal Mucosa Explant Platform to Eosinophilic Esophagitis (2019) (4)
- Development and Validation of Web-Based Tool to Predict Lamina Propria Fibrosis in Eosinophilic Esophagitis (2021) (4)
- Aiolos regulates eosinophil migration into tissues (2021) (4)
- Prospective Endoscopic Activity Assessment for Eosinophilic Gastritis in a Multisite Cohort (2022) (4)
- 537 ENDOSCOPY AND SYSTEMATIC BIOPSY OF PATIENTS WITH CHRONIC GASTROINTESTINAL SYMPTOMS LEADS TO HIGH DISCOVERY RATE OF PATIENTS WHO MEET HISTOLOGIC CRITERIA FOR EOSINOPHILIC GASTRITIS AND/OR EOSINOPHILIC DUODENITIS (2021) (4)
- Mechanism of enhanced eosinophil survival in inflammation. (2015) (4)
- PECNet: A Deep Multi-Label Segmentation Network for Eosinophilic Esophagitis Biopsy Diagnostics (2021) (4)
- Correlation of the Eosinophilic Histopathological Scoring System with Esophageal Gene Expression in Patients with Eosinophilic Esophagitis (2018) (4)
- Harnessing artificial intelligence to infer novel spatial biomarkers for the diagnosis of eosinophilic esophagitis (2022) (4)
- Summary Foxa 2 regulates alveolarization and goblet cell hyperplasia (4)
- Mast cell‐pain connection in eosinophilic esophagitis (2022) (4)
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- IL-25 and CD4 + T H 2 cells enhance ILC2-derived IL-13 production that promotes IgE-mediated experimental food allergy (2016) (3)
- IL-13 Transgene-Induced Experimental Eosinophilic Esophagitis (EE) is Associated with Increased Esophageal Circumference and Extensive Angiogenesis (2008) (3)
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- Laundry detergent promotes allergic skin inflammation and esophageal eosinophilia in mice (2022) (3)
- Epigenetic and transcriptional dysregulation in CD4+ T cells in patients with atopic dermatitis (2022) (3)
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- RAT HEPATOCYTE CULTURE PHYSIOLOGY SHOWS ENHANCED CYTOCHROME P450 ACTIVITY ON A SYNTHETIC EXTRACELLULAR MATRIX (2008) (3)
- Tefillin use induces remote ischemic preconditioning pathways in healthy men. (2018) (3)
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- CHEMOKINES, CXC | CXCL9 (MIG) (2006) (3)
- A Central Regulatory Role for Eosinophils and the Eotaxin/CCR3 Axis in Chronic Experimental Asthma (2006) (3)
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- Sa1114 - Efficacy and Safety of Rpc4046, an Anti-Interleukin-13 Monoclonal Antibody, in Patients with Active Eosinophilic Esophagitis: Analysis of the Steroid-Refractory Subgroup from the Heroes Study (2018) (2)
- Dupilumab Reduces Biomarkers of Type 2 Inflammation in Adult and Adolescent Patients With Eosinophilic Esophagitis: Results From Parts A and C of a Three-Part, Phase 3 LIBERTY EoE TREET Study (2022) (2)
- X chromosomal linkage to eosinophilic esophagitis susceptibility (2018) (2)
- Physical activity levels in urban school children with asthma (2004) (2)
- 932 HISTOLOGIC AND SYMPTOMATIC IMPROVEMENT ACROSS MULTIPLE FORMS OF EOSINOPHILIC GASTROINTESTINAL DISEASES IN ENIGMA, A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL OF ANTOLIMAB (AK002) (2020) (2)
- Analysis of Unmet Needs of Individuals Affected by Eosinophilic Gastrointestinal Disorders: Towards Health Promotion and Effective Care (2017) (2)
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- Acquired Esophageal Strictures in Children: Morphometric and Immunohistochemical Analyses (2021) (2)
- P0499 RESPONSE OF ESOPHAGEAL AND GASTROINTESTINAL MUCOSAL EOSINOPHILIA TO AN ELEMENTAL DIET TRIAL (2004) (2)
- Safety and Tolerability of Anti-IL-5 Monoclonal Antibody (Mepolizumab) Therapy in Patients with HES: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial. (2006) (2)
- Transferring allergies in the womb (2020) (2)
- Epigenetic Analysis of the Chromatin Landscape Identifies a Repertoire of Murine Eosinophil-Specific PU.1-Bound Enhancers (2021) (2)
- Interleukin-4 Receptor a S ignaling in Myeloid Cells Controls Collagen Fibril Assembly in Skin Repair Graphical (2015) (2)
- 0221: MicroRNA-21 coordinates human multipotent cardiovascular progenitors therapeutic potential and post-ischemic revascularization (2014) (2)
- The involvement of arginase and the cationic amino acid transporter 2 in asthma pathogenesis (2003) (2)
- Quantification and Regional Distribution of Eosinophils in the Gastrointestinal Tract of Children (2006) (1)
- Induction of resistin-like molecule beta (RELM-beta) by respiratory allergen, IL-4, IL-13, and STAT6 in experimental asthma (2003) (1)
- Fizz1/Relm-a Mediates IL-13ra1-independent Eosinophil Recruitment (2009) (1)
- Genome-wide admixture and association analysis identifies African ancestry specific risk loci of eosinophilic esophagitis in African American. (2022) (1)
- Eosinophils Respond to Acidic Environments with cAMP Production, Decreased Apoptosis, and a Decrease in the Expression of Pro-apoptotic Bcl-2 Family Members (2009) (1)
- Infant feeding: Swinging the Pendulum from Late to Early Introduction of Food. (2016) (1)
- The role of IL-4, IL-13, and STAT6 in experimental intestinal anaphylaxis (2003) (1)
- CHAPTER 5 – Inflammatory Effector Cells/Cell Migration (2010) (1)
- Trefoil Factor 2 (TFF2) is Induced by Allergen and IL-13 in Lung Goblet Cells and Modulates Airway Inflammatory Cell Number (2006) (1)
- 1107 The chemokine exotaxin is a central mediator of experimental eosinophilic gastrointestinal allergy (2000) (1)
- Genetic, inflammatory, and epithelial cell differentiation factors control expression of human calpain-14 (2018) (1)
- SARS-CoV-2 surveillance in households with and without asthmatic/allergic children: The Human Epidemiology and Response to SARS-CoV-2 study (HEROS) (2022) (1)
- KCNJ2 overexpression induces pro-inflammatory cytokine production, impaired barrier function and acantholysis in esophageal epithelial cells (2017) (1)
- Chapter 14 – Animal Models of Human Pathology (2013) (1)
- Bagels and LOX in patients with eosinophilic esophagitis. (2019) (1)
- Air pollution effects on childhood asthma (2004) (1)
- 539 LONG-TERM TREATMENT OF PATIENTS WITH EOSINOPHILIC GASTRITIS AND/OR EOSINOPHILIC DUODENITIS WITH LIRENTELIMAB, A MONOCLONAL ANTIBODY AGAINST SIGLEC-8 (2021) (1)
- Strong association of mast cells with eosinophilic esophagitis‐specific signatures (2022) (1)
- Validation of self-reported diagnosis of eosinophilic gastrointestinal disorders patients enrolled in the CEGIR contact registry. (2020) (1)
- Mo1187 DILATION REDUCES POSITIVE CORRELATION BETWEEN SYMPTOMS AND HISTOLOGIC FINDINGS IN ADULTS WITH EOSINOPHILIC ESOPHAGITIS (2020) (1)
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- Molecular Analysis of Duodenal Eosinophilia. (2022) (1)
- Girardi et al. Complement C5a receptors and neutrophils mediate fetal injury in the antiphospholipid syndrome. J Clin Invest 2003;112:1644-54☆ (2004) (1)
- Secondary Eosinophilic Reactions During ORAL Immunotherapy (2014) (1)
- Implicating Gene and Cell Networks Responsible for Differential COVID-19 Host Responses via an Interactive Single Cell Web Portal (2021) (1)
- Acetaminophen use and newly diagnosed asthma among women (2004) (1)
- Eosinophils Respond to Acidic environments with cAMP Generation in a TDAG8-Dependent Manner (2007) (1)
- Twin Shared Environment Increases Risk of Eosinophilic Esophagitis in Families (2012) (1)
- Scientific Journey to the First FDA-approved Drug for Eosinophilic Esophagitis. (2022) (1)
- Major link between mast cells and the idiopathic hypereosinophilic syndrome (2003) (1)
- DEEP LEARNING TISSUE ANALYSIS DIAGNOSES AND PREDICTS TREATMENT RESPONSE IN EOSINOPHILIC ESOPHAGITIS (2021) (1)
- The role of biologics in pediatric food allergy and eosinophilic gastrointestinal disorders. (2023) (1)
- Genetic Risk Variants for Celiac Disease in the IL2/IL21 Locus are Associated with Eosinophilic Esophagitis (2010) (1)
- An Allergic Basis for Abdominal Pain. (2021) (1)
- Toll-Like Receptor Signaling Inhibits Eosinophilopoiesis. (2010) (1)
- Resistin-like molecule (RELM)-alpha and beta are allergen-induced cytokines with potent remodeling activity in the murine lung (2004) (1)
- Independent Pathways Asthma : Identification of STAT 6-Dependent Transcript Signatures in Experimental and (2004) (1)
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- An International, Retrospective Study of Off-Label Biologic Use in the Treatment of Hypereosinophilic Syndromes (HES) (2021) (1)
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- Long-term Safety And Efficacy Of Mepolizumab For The Treatment Of Hypereosinophilic Syndrome (2012) (1)
- IL-13 Mediated Lung Effects Are Exclusively Dependent On IL-13Ralpha1 (CD213a) (2008) (1)
- Culpable role for eosinophils in asthma remodeling (2004) (1)
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- 46 – Eosinophil-associated gastrointestinal disorders (EGID) (2008) (1)
- Dose-dependent respiratory responses to inhaled corticosteroids in asthma (2004) (1)
- Gene expression profile analysis in experimental asthma (2002) (1)
- 628 Corticosteroid-Sparing Effects of Mepolizumab, an Anti-Interleukin-5 Monoclonal Antibody, in Patients With Hypereosinophilic Syndrome (2007) (1)
- Epigenetic and Transcriptional Dysregulation in CD4+ T cells of Patients with Atopic Dermatitis (2021) (1)
- The chemokine monokine induced by IFN-g (Mig, CXCL9) is potent inhibitor of eosinophils in vitro and in vivo (2003) (1)
- Resistin Like Molecule Beta Regulates Intestinal Inflammation in Chronic Colitis (2007) (1)
- Eosinophilic esophagitis endotype classification by molecular, clinical, and histopathological analyses: a cross sectional study by the Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR) (2018) (1)
- News Beyond Our Pages. (2018) (1)
- Gene-environment Interaction in Pediatric Eosinophilic Esophagitis: 422 (2016) (0)
- Fantastic new insight into mechanisms of lung TH2 responses (2004) (0)
- Esophageal mucosal transcriptional alterations persist in eosinophilic esophagitis patients during remission (2022) (0)
- Mechanisms of Allergic Inflammation in the Gut and Skin (2017) (0)
- Phenotypic Characterization of the Eosinophilic Esophagitis (EoE) Population in the Consortium of Food Allergy Research (CoFAR) (2015) (0)
- Dysregulation of the Desmosomal Cadherin Desmoglein-1 in Eosinophilic Esophagitis (2011) (0)
- Development and Application of a Functional Human Esophageal Mucosa Explant Platform to Eosinophilic Esophagitis (2019) (0)
- 818 – Cytokine Expression Illustrates Heterogeneity of Active Eosinophilic Esophagitis in a Large Multi-Site Cohort (2019) (0)
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- Efficacy and safety of mepolizumab in hypereosinophilic syndrome: Aphase III, randomized, placebo-controlled trial (2020) (0)
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- OSINOPHILIC esophagitis (EoE) is a recently recognized chronic food allergic disease associated with esophageal specific inflammation characterized by high levels of eosinophils [1]. An allergic etiology is strongly supported by the efficacy of food elimination diets, the co-occurrence of EoE (2021) (0)
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- Masters of Immunology Eosinophils and Cancer (2013) (0)
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- Fr173 OPTIMIZATION OF EOSINOPHILIC GASTRITIS/DUODENITIS DETECTION REQUIRES EVALUATION OF MULTIPLE HIGH-POWERED FIELDS IN EACH OF 8 GASTRIC AND 4 DUODENAL BIOPSIES: ANALYSIS FROM A RANDOMIZED TRIAL (2021) (0)
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- Identification of Glucocorticoid-Regulated Transcripts in Eosinophilic Esophagitis--The Role of FKBP51 (2009) (0)
- Hyperreactivity Degranulation and the Induction of Bronchial the Lung on Eosinophil Trafficking and The Effect of IL-5 and Eotaxin Expression in (2000) (0)
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- Su1001 CLINICAL CHARACTERISTICS AND DISEASE FEATURES FROM A MULTICENTER LONGITUDINAL COHORT OF EOSINOPHILIC GASTROINTESTINAL DISORDERS MAY INFORM FUTURE STUDIES (2020) (0)
- Sa1116 - Demographic Features of Eosinophilic Gastritis, Enteritis and Colitis Using 10 Years of Retrospective Data from a Multi-Center Consortium (2018) (0)
- IL-33 is induced in undifferentiated, non-dividing esophageal epithelial cells in eosinophilic esophagitis (2017) (0)
- The cationic amino acid transporter 2 regulates innate and allergen-induced adaptive immune responses in the lung (2005) (0)
- Anti-IL-5 Therapy (Mepolizumab) in Hypereosinophilic Syndromes and Eosinophilic Esophagitis: Cytokine Secretion and Decreased Peripheral Blood Eosinophilia (2006) (0)
- Murphy et al. Maternal asthma is associated with reduced female fetal growth. Am J Respir Crit Care Med 2003;168:1317-23 (2004) (0)
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- Differential expression of surface receptors and adhesion molecules on eosinophil subpopulations (2002) (0)
- S1431 Similar Efficacy of Lirentelimab in Patients With New vs Prior Diagnoses of Eosinophilic Gastritis and/or Duodenitis in a Randomized Trial (2021) (0)
- Letters to the EditorBeyond our pages (2003) (0)
- Anti–IL-5 treatment improves airway remodeling in asthmatic individuals (2004) (0)
- P309 Characteristics of eosinophilic esophagitis in African-American preschoolers: a case series (2016) (0)
- FIP1L1/PDGFRa Synergizes with SCF/c-Kit Signaling To Induce Systemic Mastocytosis in a Chronic Eosinophilic Leukemia Murine Model (2007) (0)
- Longitudinal Association of Parent and Child Patient Reported Outcomes in Eosinophilic Esophagitis in a Multicenter Cohort (2022) (0)
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- Human Epidemiology and RespOnse to SARS-CoV-2 (HEROS): Objectives, Design and Enrollment Results of a 12-City Remote Observational Surveillance Study of Households with Children using Direct-to-Participant Methods (2022) (0)
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- 619 HIGH DISCOVERY RATE OF GASTRODUODENAL EOSINOPHILIA BUT NOT EOSINOPHILIC ESOPHAGITIS IN PATIENTS WITH CHRONIC GASTROINTESTINAL SYMPTOMS (2021) (0)
- Atasoy et al. Regulation of eotaxin gene expression by TNF-α and IL-4 through mRNA stabilization: involvement of the RNA-binding protein HuR1. J Immunol 2003;171:4369-78 (2004) (0)
- 488 Epithelial cells are the major cellular source of eotaxin mRNA in the Guinea pig lung (1996) (0)
- Sa.60. Anti-IL-5 Therapy (Mepolizumab) for Eosinophilic Esophagitis: Cytokine Secretion and Decreased Peripheral Blood and Esophageal Eosinophilia (2006) (0)
- Mo1127 – Mast Cells in Addition to Eosinophils are Markedly Elevated At Baseline in Patients with Eosinophilic Gastritis And/Or Gastroenteritis (2019) (0)
- Su1754 – Overestimation of the Prevalence of Eosinophilic Colitis with Reliance on a Single Billing Code (2019) (0)
- DISCOVERY AND UNDERSTANDING OF A NEW CHRONIC FOOD ALLERGY DISORDER: EOSINOPHILIC ESOPHAGITIS (2013) (0)
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- Altered innate and allergic immune responses in SP-D deficient mice (2002) (0)
- Impact of Baseline Blood Eosinophil Count on Flare Reduction in Mepolizumab-Treated Patients With Hypereosinophilic Syndrome (2021) (0)
- Anti–IL-13 (cendakimab) administration improves esophageal gene expression in eosinophilic esophagitis (2023) (0)
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- TITLE : Genetics of Eosinophilic Esophagitis PRINCIPAL INVESTIGATOR : (2012) (0)
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- Sa1123 - Histologic Characterization of a Multi-Center Retrospective Cohort of Patients with Eosinophilic Gastrointestinal Disorders (2018) (0)
- Su1953 Esophageal Strictures in Children Contain Focal Obliterative Muscularization and Mural Inflammation (2014) (0)
- FIP1L1/PDGFRA (F/P) Fusion Gene Induces Eosinophil Development, Activation, and Survival Synergistically with SCF and IL-5 (2008) (0)
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- S381 Esophageal Eosinophil Count Does Not Correlate With the Endoscopic Reference Score Remodeling Subscore in Placebo-Treated Eosinophilic Esophagitis Patients in the Phase 2 Proof-of-Concept and Phase 3 TREET Studies (2021) (0)
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- The E3 ubiquitin ligase midline 1 promotes allergen and rhinovirus-induced asthma by inhibiting protein phosphatase 2A activity | NOVA. The University of Newcastle's Digital Repository (2013) (0)
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- Resistin-like molecule (RELM)-alpha and beta are cytokines with inflammatory and remodeling activity in Th2-associated asthmatic responses (2005) (0)
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- The Anti-protease SPINK7 is a Checkpoint Regulator of Esophageal Epithelial Inflammatory Responses (2018) (0)
- McLachlin et al. Mast cell–derived tumor necrosis factor induces hypertrophy of draining lymph nodes during infection. Nat Immunol 2003;4:1199-205 (2004) (0)
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- 405 Dupilumab normalizes expression of type 2 inflammatory genes (2021) (0)
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- Fr191 EOSINOPHILIC GASTRITIS AND EOSINOPHILIC DUODENITIS EXHIBIT A SIMILAR CLINICAL PRESENTATION, UNDERSCORING THE NEED FOR COLLECTION OF MULTIPLE BIOPSIES FROM BOTH THE STOMACH AND DUODENUM TO EVALUATE FOR TISSUE EOSINOPHILIA: ANALYSIS FROM A RANDOMIZED TRIAL (2021) (0)
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- Critical Role Of Antigen-Specific Lymphocytes In The Induction Of Asthma Associated Eosinophilic Esophagitis (EE) (2006) (0)
- Hypereosinophilic syndrome in Europe: retrospective study of treatment patterns, clinical manifestations, and healthcare resource utilization. (2023) (0)
- S387 Dupilumab Improves Clinical, Symptomatic, Histologic, and Endoscopic Aspects of EoE up to 24 Weeks: Pooled Results From Parts A and B of Phase 3 LIBERTY-EoE-TREET (2022) (0)
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- 724 A Critical Role of Interleukin-15 in the Pathogenesis of Eosinophilic Esophagitis (2008) (0)
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- 1244 Symptomatic Patients Suspected of Eosinophilic Gastritis and/or Enteritis Have Elevated Mucosal Mast Cell Counts Without Eosinophilia: A New Diagnostic Entity? (2019) (0)
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- Dupilumab in Patients with Eosinophilic Esophagitis. Reply. (2023) (0)
- Increased allergic airway responses in a murine model of intestinal anaphylaxis (2004) (0)
- Mo1185 Substantial Variability in Biopsy Practice Patterns Among Gastroenterologists for Suspected Eosinophilic Gastrointestinal Disorders (EGID) (2016) (0)
- Eosinophils and eosinophil chemokines, CCL11, CCL24 and CCL26, in refractory pediatric Crohnʼs Disease: O-0011 (2007) (0)
- In Memory and Celebration: Dr. James J. Lee (2017) (0)
- Dual roles for LPS depending on concentration (2003) (0)
- How the Esophageal Epithelial Cells Shape the Immune Response in Eosinophilic Esophagitis (2015) (0)
- Negative Regulation of Eosinophil Production by Toll-Like Receptors (2012) (0)
- SCF and IL-5 Synergize with FIP1L1/PDGFRα To Induce Mastocytosis in a Chronic Eosinophilic Leukemia Murine Model. (2006) (0)
- Glucocorticoid-mediated FKBP51 Gene Expression in Esophageal Epithelial Cells (2010) (0)
- Faculty Opinions recommendation of The 2010-2015 Prevalence of Eosinophilic Esophagitis in the USA: A Population-Based Study. (2017) (0)
- Rac2 Function in Eosinophil Superoxide Generation and Allergic Airway Inflammation (2008) (0)
- Faculty Opinions recommendation of Prospective, comparative effectiveness trial of cow's milk elimination and swallowed fluticasone for pediatric eosinophilic esophagitis. (2017) (0)
- Harmful role of mast cells in septic shock (2004) (0)
- The effect of nebulized magnesium sulfate on the treatment of acute asthma (2003) (0)
- Sex of Parent is Associated with Familial Risk of Eosinophilic Esophagitis (2011) (0)
- IL-13 IS OVEREXPRESSED IN EOSINOPHILIC ESOPHAGITIS AND INDUCES EOTAXIN-3 EXPRESSION BY A STAT6-DEPENDENT AND FLUTICASONE PROPIONATE-INHIBITED PATHWAY IN ESOPHAGEAL EPITHELIAL CELLS (2006) (0)
- Iconographies supplémentaires de l'article : High prevalence of eosinophilic esophagitis in patients with inherited connective tissue disorders (2013) (0)
- Sisk et al. Cost-effectiveness of vaccination against invasive pneumococcal disease among people 50 through 64 years of age: Role of comorbid conditions and race. Ann Intern Med 2003 17;138:960-8 (2004) (0)
- Faculty Opinions recommendation of Efficacy of Proton Pump Inhibitor Drugs for Inducing Clinical and Histologic Remission in Patients With Symptomatic Esophageal Eosinophilia: A Systematic Review and Meta-Analysis. (2017) (0)
- Regulation of Human Eosinophil Phenotype (1989) (0)
- Another protease identified as an asthma master gene (2004) (0)
- 736 Eotaxin-deficient mice develop Airway Eosinophilia and Airway Hyperresponsiveness (AHR) following ovalbium sensitization and challenge (2000) (0)
- Interleukin-(IL)-13 mediates biphasic airways hyperreactivity through the IL-4 receptor-alpha chain and STAT-6 independently of IL-5 and eotaxin (2002) (0)
- New data support a downregulatory role for the alternate IL-13 receptor (2003) (0)
- Chapter 37 – Eosinophils (2005) (0)
- The Editors[rsquo ] Choice (2000) (0)
- Individual and combined gene deletions reveal that the eotaxin chemokines and CCR3 fundamentally regulate allergen-induced pulmonary eosinophilia (2005) (0)
- The FIP1-like-1 (FIP1L1)- Platelet-Derived Growth Factor Receptor Alpha (PDGFR alpha) fusion gene cooperates with IL-5 to induce a hypereosinophilic syndrome (HES)-like disease in a murine model (2005) (0)
- Extracellular Flux as an Indicator of Cellular Metabolism (2004) (0)
- Epigenetic and Transcriptional Dysregulation in T cells of Patients with Atopic Dermatitis (2022) (0)
- Mucosal Microbiota Associated With Eosinophilic Esophagitis and Eosinophilic Gastritis (2022) (0)
- Other Articles of Interest (1988) (0)
- Sa.49. Anti-IL-5 Therapy (Mepolizumab) for Eosinophilic Esophagitis: Cytokine Secretion and Decreased Peripheral Blood and Esophageal Eosinophilia (2006) (0)
- Diagnostics and Therapeutic Targets for Eosinophilic Esophagitis (2005) (0)
- Faculty Opinions recommendation of Eosinophils in the zebrafish: prospective isolation, characterization, and eosinophilia induction by helminth determinants. (2010) (0)
- Mechanism of glucocorticoid resistance (2004) (0)
- Role for Mast Cell Chymase in Intestinal Epithelial Permeability (2008) (0)
- A Novel Model of Transgene-Induced Eosinophilic Esophagitis (2006) (0)
- Paired Immunoglobulin-like Receptor B Is Required For Allergic Eosinophilic Airway Inflammation (2012) (0)
- News Beyond Our Pages (2019) (0)
- Subcellular Localization of CAPN14 in Human Esophageal Epithelial Cells (2016) (0)
- Faculty Opinions recommendation of Topical Steroid Therapy for the Treatment of Eosinophilic Esophagitis (EoE): A Systematic Review and Meta-Analysis. (2017) (0)
- Eosinophil progenitor levels correlate with disease activity as assessed by the eosinophilic esophagitis histologic scoring system in pediatric eosinophilic esophagitis (2018) (0)
- Iconographies supplémentaires de l'article : News Beyond Our Pages (2011) (0)
- Raghu et al. A placebo-controlled trial of interferon gamma-1b in patients with idiopathic pulmonary fibrosis. N Engl J Med 2004;350:125-33 (2004) (0)
- The Effect of IL-13R·2 on IL-13 Transgene-Induced Experimental Eosinophilic Esophagitis (2009) (0)
- CONSENSUS DOCUMENT ICON : Eosinophil Disorders (0)
- Esophageal Epithelium and Lamina Propria are Unevenly Involved in Eosinophilic Esophagitis. (2023) (0)
- Harnessing Digital Pathology And Causal Learning To Improve Eosinophilic Esophagitis Dietary Treatment Assignment (2023) (0)
- Retrospective Identification of a Unique Cohort of Patients with Eosinophilic Esophagitis (2009) (0)
- Esophageal Remodeling Develops as a Consequence of Tissue Specific Interleukin (IL)-5 Induced Eosinophilia (2008) (0)
- Can individuals allergic to sulfa antibiotic agents tolerate nonantibiotics containing the sulfa moiety (2004) (0)
- Increased High Molecular Weight IL-5 Complex After Anti-IL-5 (Mepolizumab) Therapy (2008) (0)
- Genetic variants at the 16p13 locus confer risk for eosinophilic esophagitis (2018) (0)
- A key role for IL-13 signaling via the type 2 IL-4 receptor in atopic dermatitis (2020) (0)
- Su1167: THE ASSOCIATION BETWEEN HISTOLOGIC ABNORMALITIES AND HEALTH RELATED QUALITY OF LIFE IN PEDIATRIC PATIENTS WITH EOSINOPHILIC ESOPHAGITIS (2022) (0)
- Il-13 Is Overexpressed In Eosinophilic Esophagitis And Induces Eotaxin-3 Expression In Esophageal Epithelial Cells (2007) (0)
- Model of Cutaneous Inflammation 2 Has a Protective Role in a Mouse a IL-13R (0)
- The Pan-B Cell Marker CD22 (siglec 2) Is Expressed On Gastro-intestinal (GI) Eosinophils And Negatively Regulates GI Eosinophil Survival (2011) (0)
- Beyond Our Pages (2005) (0)
- A connection found between mast cells and pain in eosinophilic esophagitis (2022) (0)
- Rac it up (2004) (0)
- Airway Disease and Human Asthma Importance of Cytokines in Murine Allergic (2010) (0)
- Su1110 IL-13-Induced Dilated Intracellular Space (DIS) Formation in Esophageal Epithelial Cells Is Dependent on SLC9A3 Function (2015) (0)
- AJG-21-1701 272..279 (0)
- Pumping mast cells out of allergic inflammation-Are proton pump inhibitors taking center stage? (2020) (0)
- TRAIL Signalling Is Pro-Inflammatory in Eosinophilic Esophagitis (2015) (0)
- Dupilumab suppresses type 2 biomarkers of inflammation in patients with eosinophilic esophagitis: from Part B of LIBERTY-EoE-TREET (2023) (0)
- Faculty Opinions recommendation of PIRs mediate innate myeloid cell memory to nonself MHC molecules. (2020) (0)
- Fr179 CHARACTERISTICS OF EOSINOPHILIC ESOPHAGITIS IN A DIVERSE COHORT OF PEDIATRIC AND ADULT PATIENTS: A MULTI-SITE STUDY (2021) (0)
- Ask the Experts: EoE Open Mic (2016) (0)
- Comparison of Patients with Eosinophilic Esophagitis with Extremely High and Low Esophageal Eosinophil Counts (2020) (0)
- 815 Characterization of the CCR3 gene reveals differential 5′ exon usage and a non-polymorphic eosinophil promoter (2000) (0)
- A virus that diverts immunity (2003) (0)
- Role of Th2-molecules in OVA-Induced Intestinal Anaphylaxis (2007) (0)
- Crosstalk between Aryl Hydrocarbon Receptor (AHR) Pathway and IL-13 Signaling in Human Keratinocytes and Implications for Atopic Dermatitis (2023) (0)
- 989: DUPILUMAB IMPROVES HISTOLOGIC AND CLINICAL ASPECTS OF DISEASE IN ADULT AND ADOLESCENT PATIENTS WITH EOSINOPHILIC ESOPHAGITIS AT WEEK 24: RESULTS FROM PART B OF THE 3-PART LIBERTY EOE TREET STUDY (2022) (0)
- Subject Index Vol. 149, Suppl. 1, 2009 (2009) (0)
- Faculty Opinions recommendation of Cadherin-11 regulates fibroblast inflammation. (2011) (0)
- Radcliffe et al. Enzyme potentiated desensitization in treatment of seasonal allergic rhinitis: a double blind randomized controlled study. BMJ 2003;327:251-4 (2004) (0)
- F.2. An Experimental Model of Eosinophilic Esophagitis Induced by the Lung Specific IL-13 Transgene Resembles Human Eosinophilic Esophagitis in Morphology and Gene Expression (2008) (0)
- Refining the definition of hypereosinophilic syndrome The Harvard community has made this article openly available. Please share how this access benefits you. Your story matters (2012) (0)
- Su1104 Dysregulation of SLC9A3 Function in Eosinophilic Esophagitis (2015) (0)
- Patients with eosinophilic esophagitis have a high baseline burden of atopic/allergic comorbidities: from Parts A and B of LIBERTY-EoE-TREET (2023) (0)
- Effects of treatment with budesonide versus cromolyn on quality-of-life manifestations in childhood asthma (2004) (0)
- Arginine Metabolism: Enzymology, Nutrition, and Clinical Significance Arginine in Asthma and Lung Inflammation 1,2 (2004) (0)
- 266 Murine eataxin-2: A constitutive chemokine induced by allergen challenge and IL-4 (2000) (0)
- 233. ENDOSCOPIC REFERENCE SCORE AND HISTOLOGICAL SCORING SYSTEM ARE COMPLEMENTARY ASSESSMENTS FOR CHARACTERIZING FIBROSTENOTIC OR INFLAMMATORY PHENOTYPES IN EOSINOPHILIC ESOPHAGITIS PATIENTS (2022) (0)
- Korsgren et al. Neural expression and increased lavage fluid levels of secretoneurin in seasonal allergic rhinitis. Am J Respir Crit Care Med 2003;167:1504-8 (2004) (0)
- Shared Genetic Etiology Between Eoe and Other Allergic Diseases (2015) (0)
- Natural history of asthma from childhood into adulthood (2004) (0)
- Eosinophil progenitor levels are increased in active pediatric eosinophilic esophagitis (2016) (0)
- FIP1L1-PDGFRα Induces Stem Cell Factor Dependent Eosinophil and Mast Cell Development from Murine Hematopoietic Stem Cell/Progenitors in Vitro (2006) (0)
- Protection against Acute Schistosomiasis Cells Is Necessary and Sufficient for Host Expression by Bone Marrow-Derived a IL-4R (0)
- This information is current as Hypersensitivity the Severity of Delayed-Type Pathway , Th 1 Polarization , and γ IL-12 / IFN-Response-Mediated Activation of the MicroRNA-21 Limits In Vivo Immune (2011) (0)
- 2007 E. Mead Johnson Award: Scientific Pursuit of the Allergy Problem (2008) (0)
- Stem Cell Factor Signaling Collaborates in the Development of FIP1L1/PDGFRα Induced Chronic Eosinophilic Leukemia in a Murine Model (2008) (0)
- Role Of Hormone Signaling In Eosinophilic Esophagitis: 17-Beta Estradiol Attenuation Of IL-13 Induced Barrier Dysfunction In Esophageal Epithelium (2017) (0)
- Sa1112 - Endoscopic Features are Significantly Associated with Histologic Measures of Disease Activity in Patients with Active Eosinophilic Esophagitis: A Post HOC Analysis of a Randomized, Placebo-Controlled, Phase 2 Dupilumab Trial (2018) (0)
- Bronchial hyperresponsiveness in experimental eosinophil-associated GI diseases is critically regulated by CD4+ T-cells, interleukin-13 and eotaxin (2004) (0)
- News beyond our pagesNews Beyond Our Pages (2013) (0)
- De Swert et al. Myopathy in children receiving high-dose inhaled fluticasone. N Engl J Med 2004;350:1157 (2004) (0)
- Precursor Maturation Network That Promotes Eosinophil IL-5 Triggers a Cooperative Cytokine (2014) (0)
- 230. ENDOSCOPIC REFERENCE SCORE REMODELING SUBSCORE AND ESOPHAGEAL EOSINOPHIL COUNT DO NOT CORRELATE IN PLACEBO-TREATED EOSINOPHILIC ESOPHAGITIS PATIENTS FROM DUPILUMAB STUDIES (2022) (0)
- Il-13 Receptor Alpha 1 Critically Regulates Lung Sensitization and Subsequent Inflammation (including Eosinophilia) in Response to Aspergillus Fumigatus (2010) (0)
- 165 – Development of the Eosinophilic Gastritis Molecular Diagnostic Panel (2019) (0)
- Dupilumab efficacy and safety up to 52 weeks in adult and adolescent patients with eosinophilic esophagitis: Results from parts B and C of the randomized, placebo-controlled, three-part, phase 3 LIBERTY EoE TREET Study (2023) (0)
- 821 Effects of Mepolizumab, an Anti-Interleukin-5 Monoclonal Antibody, on Blood Eosinophil Counts in Patients With Hypereosinophilic Syndrome (2007) (0)
- Monocyte / Macrophage-Derived CCL 11 Inflammatory + CCR 2 high Experimental Colitis Is Mediated by Ly 6 C Colonic Eosinophilic Inflammation in (2011) (0)
- An international registry of patients with eosinophilic esophagitis (2003) (0)
- Eosinophilic Esophagitis: Management Approaches (2018) (0)
- Faculty Opinions recommendation of Disease activity in eosinophilic esophagitis is associated with impaired esophageal barrier integrity. (2017) (0)
- The CCR3 promoter directs expression of a reporter gene in transgenic mice (2002) (0)
- S1405 Endoscopy and Systematic Biopsy of Patients With Moderate-Severe Unexplained Gastrointestinal Symptoms Compared With Healthy Controls: High Discovery Rate of Eosinophilic Gastritis and/or Eosinophilic Duodenitis (2021) (0)
- Revelation of new asthma genes (2004) (0)
- 515 microRNA-375-KLF5 Regulation of Intestinal Epithelial CFTR Function (2015) (0)
- Intraesophageal administration of oxazolone to skin-sensitized mice results in experimental eosinophilic esophagitis resembling human disease (2020) (0)
- Abstract 11617: Proangiogenic Hematopoietic Progenitor-Derived Eotaxins Promote Pathological Angiogenesis and Airway Inflammation in Asthma (2014) (0)
- The Effect Of SLC9A3 On Esophageal Epithelium In Eosinophilic Esophagitis (EoE) (2017) (0)
- 725 Periostin Facilitates Eosinophil Tissue Infiltration In Vivo and In Vitro (2008) (0)
- CLINICAL — ALIMENTARY TRACT Ef fi cacy of Dupilumab in a Phase 2 Randomized Trial of Adults With Active Eosinophilic Esophagitis (0)
- 19 – Eosinophilia: Clinical manifestations and therapeutic options (2012) (0)
- Acoustic metamaterials-driven transdermal drug delivery for rapid and on-demand management of acute disease (2023) (0)
- Sa1117 - Treatment Patterns for Eosinophilic Gastritis, Enteritis and Colitis Vary Across Sites and Patient Age in a Multi-Center Consortium (2018) (0)
- Reslizumab in Children and Adolescents With Eosinophilic Esophagitis: Results of a Double-Blind, Randomized, Placebo-Controlled Study (2011) (0)
- Dysphagia Days as a Clinical Marker of EoE Treatment Response in Steroid-Refractory Patients (2022) (0)
- IL-13 Receptors in Cutaneous Inflammation (2007) (0)
- Diagnostic Inaccuracy Of Biopsy Evaluations In Eosinophilic Esophagitis Underscores The Value Of a Secondary Review Process (2014) (0)
- Introduction to TIGERS and CEGIR (2018) (0)
- Molecular and cellular determinants associated with clinical parameters of eosinophilic gastritis (2023) (0)
- Mast Cells Regulation of Homeostatic Intestinal Barrier Function is dependent on the Human Chymase Homologue, mcpt4. (2009) (0)
- SPINK7 in Allergic Inflammation (2018) (0)
- Allergy and Immunology Division Photo (2009) (0)
- Gastroesophageal Reflux Disease and Eosinophilic Esophagitis in Children With Complex Airway Disease (2019) (0)
- Fr176 ENDOSCOPIC APPEARANCE DOES NOT PREDICT THE PRESENCE OF HISTOLOGIC EOSINOPHILIC GASTRITIS AMONG SYMPTOMATIC ADULTS, INDICATING THAT COLLECTION AND EVALUATION OF BIOPSIES SHOULD OCCUR REGARDLESS OF ENDOSCOPIC APPEARANCE: ANALYSIS FROM A RANDOMIZED TRIAL (2021) (0)
- Isolation of alpha-melanotropin from the pars intermedia of the larval amphibian, Ambystoma tigrinum. (1987) (0)
- Efficacy of RPC4046, an Anti‐Interleukin‐13 Monoclonal Antibody, in Patients With Active Eosinophilic Esophagitis: Analysis of the Steroid‐Refractory Subgroup From the HEROES Study: 934 (2019) (0)
- Eotaxin-3 Promoter Leads to the Elevated Expression Demethylation of the Human Eotaxin-3 Gene (2013) (0)
- Driven Autoinflammatory Loop − IL-4 Mechanism Differentially Dependent upon an Dependent − B κ Eosinophils by an NF-IL-33 Markedly Activates Murine Barski (2013) (0)
- ALIMENTARY TRACT Long-term Efficacy and Tolerability of RPC4046 in an Open-Label Extension Trial of Patients With Eosinophilic Esophagitis (2021) (0)
- S420 The Histological Scoring System and Endoscopic Reference Score Are Complementary Assessments for Characterizing Fibrostenotic or Inflammatory Phenotypes in Patients with Eosinophilic Esophagitis (2021) (0)
- News Beyond Our Pages. (2021) (0)
- Protease allergens as initiators–regulators of allergic inflammation (2023) (0)
- 735 Esophageal eosinophilis are regulated by allergen challenge, IL-5 and eotaxin (2000) (0)
- Eosinophilic Esophagitis Epithelial Differentiation Cluster Genes in Coordinate Interaction between IL-13 and (2010) (0)
- Mast Cell Chymase Regulates Homeostatic Intestinal Barrier Function (2009) (0)
- Abstract 403: MicroRNA-21 Ablation Exacerbates Aldosterone-mediated Cardiac Inflammation, Fibrosis, Hypertrophy and Dysfunction (2014) (0)
- Mechanism of anemia of chronic disease elucidated (2004) (0)
- Molecular Diagnosis of Eosinophilic Esophagitis from a Single Esophageal Biopsy (2020) (0)
- MicroRNA‐21 Ablation Exacerbates Aldosterone‐Mediated Renal Injury (2017) (0)
- Maternal tolerance to the fetus is mediated by regulatory T cells (2004) (0)
- A novel approach at evaluating eosinophil-associated gastrointestinal disorders using a world-wide-web based registry (2002) (0)
- Deletion of SPINK7 by CRISPR/Cas9 Elicits Pro-Inflammatory and Impaired Epithelial Barrier Responses in Esophageal Epithelial Cells (2018) (0)
- Macrophage-derived CCL11/eotaxin-1 mediates eosinophil recruitment and effector function in ulcerative colitis: O-019. (2008) (0)
- Epidermal allergen sensitization primes for aeroallergen induced eosinophilic esophagitis (EE) (2004) (0)
- 867a: CLINICAL AND HISTOLOGICAL IMPROVEMENTS WITH WEEKLY DUPILUMAB TREATMENT IN ADULT AND ADOLESCENT PATIENTS WITH EOSINOPHILIC ESOPHAGITIS AT WEEK 24: WEEKLY AND EVERY 2 WEEKS’ RESULTS FROM PART B OF THE 3-PART LIBERTY EOE TREET STUDY (2022) (0)
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