Marc K. Jenkins

Q: What Schools Are Affiliated With Marc K. Jenkins

Marc K. Jenkins is affiliated with the following schools: University of Amsterdam, University of Minnesota, Stanford University, Johns Hopkins University, University of California, San Francisco

Marc K. Jenkins's AcademicInfluence.com Rankings

Marc K. Jenkins

Biology

#6015

World Rank

#8629

Historical Rank

#1991

USA Rank

Immunology

#333

World Rank

#346

Historical Rank

#76

USA Rank

biology Degrees

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Biology

Marc K. Jenkins's Degrees

PhD Immunology University of California, San Francisco
Doctorate Medicine Johns Hopkins University

Why Is Marc K. Jenkins Influential?

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According to Wikipedia, Marc K. Jenkins is a Regents Professor and Director of the Center for Immunology at the University of Minnesota. He is a member of the National Academy of Sciences. Education Jenkins received his B.S. in Microbiology from the University of Minnesota in 1980. He completed his Ph.D. in Microbiology and Immunology in 1985 from Northwestern University and then conducted postdoctoral training in the Laboratory of Immunology at the National Institutes of Health from 1985 to 1988.

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Marc K. Jenkins's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Clonal expansion versus functional clonal inactivation: a costimulatory signalling pathway determines the outcome of T cell antigen receptor occupancy. (1989) (1591)
Antigen presentation by chemically modified splenocytes induces antigen- specific T cell unresponsiveness in vitro and in vivo (1987) (1244)
Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo. (1994) (1117)
Visualizing the generation of memory CD4 T cells in the whole body (2001) (1113)
Naive CD4(+) T cell frequency varies for different epitopes and predicts repertoire diversity and response magnitude. (2007) (949)
Visualization of specific B and T lymphocyte interactions in the lymph node. (1998) (835)
Distinct dendritic cell populations sequentially present antigen to CD4 T cells and stimulate different aspects of cell-mediated immunity. (2003) (768)
Inflammatory cytokines provide a third signal for activation of naive CD4+ and CD8+ T cells. (1999) (677)
Normalizing the environment recapitulates adult human immune traits in laboratory mice (2016) (651)
In Vivo Detection of Dendritic Cell Antigen Presentation to CD4+ T Cells (1997) (622)
CD28 delivers a costimulatory signal involved in antigen-specific IL-2 production by human T cells. (1991) (586)
In vivo activation of antigen-specific CD4 T cells. (2001) (528)
Antigen presentation to naive CD4 T cells in the lymph node (2003) (504)
Different B Cell Populations Mediate Early and Late Memory During an Endogenous Immune Response (2011) (488)
Linked T cell receptor and cytokine signaling govern the development of the regulatory T cell repertoire. (2008) (425)
Inhibition of antigen-specific proliferation of type 1 murine T cell clones after stimulation with immobilized anti-CD3 monoclonal antibody. (1990) (413)
Focused Specificity of Intestinal Th17 Cells towards Commensal Bacterial Antigens (2014) (411)
Single Naive CD4+ T Cells from a Diverse Repertoire Produce Different Effector Cell Types during Infection (2013) (404)
The humoral immune response is initiated in lymph nodes by B cells that acquire soluble antigen directly in the follicles. (2007) (397)
Opposing signals from the Bcl6 transcription factor and the interleukin-2 receptor generate T helper 1 central and effector memory cells. (2011) (397)
Naïve and Memory CD4+ T Cell Survival Controlled by Clonal Abundance (2006) (389)
Origins of CD4+ effector and central memory T cells (2011) (379)
Antigen-dependent clonal expansion of a trace population of antigen-specific CD4+ T cells in vivo is dependent on CD28 costimulation and inhibited by CTLA-4. (1995) (362)
Effects of cyclosporine A on T cell development and clonal deletion. (1988) (357)
A germinal center–independent pathway generates unswitched memory B cells early in the primary response (2012) (322)
Molecular events in the induction of a nonresponsive state in interleukin 2-producing helper T-lymphocyte clones. (1987) (310)
Inflammatory cytokines enhance the in vivo clonal expansion and differentiation of antigen-activated CD4+ T cells. (1997) (309)
Different routes of bacterial infection induce long-lived TH1 memory cells and short-lived TH-17 cells (2009) (284)
Tracking epitope-specific T cells (2009) (283)
Clonal anergy is induced in vitro by T cell receptor occupancy in the absence of proliferation. (1991) (277)
Characterization of CD4+ T Cell Responses During Natural Infection with Salmonella typhimurium1 (2000) (274)
A Natural Immunological Adjuvant Enhances T Cell Clonal Expansion through a CD28-dependent, Interleukin (IL)-2–independent Mechanism (1998) (271)
The Role of Naive T Cell Precursor Frequency and Recruitment in Dictating Immune Response Magnitude (2012) (263)
Allogeneic non-T spleen cells restore the responsiveness of normal T cell clones stimulated with antigen and chemically modified antigen-presenting cells. (1988) (262)
Tracking salmonella-specific CD4 T cells in vivo reveals a local mucosal response to a disseminated infection. (2002) (258)
The ups and downs of T cell costimulation. (1994) (257)
Direct evidence that functionally impaired CD4+ T cells persist in vivo following induction of peripheral tolerance. (1998) (251)
Use of adoptive transfer of T‐cell antigen‐receptor‐transgenic T cells for the study of T‐cell activation in vivo (1997) (246)
Class II MHC-bearing keratinocytes induce antigen-specific unresponsiveness in hapten-specific Th1 clones. (1988) (245)
Molecules involved in T-cell costimulation. (1993) (243)
The anatomy of T-cell activation and tolerance. (1996) (229)
Kinetics of CD4+ T cell repopulation of lymphoid tissues after treatment of HIV-1 infection. (1998) (227)
The role of cell division in the induction of clonal anergy. (1992) (222)
Antibody Is Required for Protection against Virulent but Not Attenuated Salmonella entericaSerovar Typhimurium (2000) (220)
Development of a Novel Transgenic Mouse for the Study of Interactions Between CD4 and CD8 T Cells During Graft Rejection (2003) (219)
On the composition of the preimmune repertoire of T cells specific for Peptide-major histocompatibility complex ligands. (2010) (217)
Recapitulating adult human immune traits in laboratory mice by normalizing environment (2016) (187)
Visualizing the first 50 hr of the primary immune response to a soluble antigen. (2004) (182)
Distinct functions of antigen-specific CD4 T cells during murine Mycobacterium tuberculosis infection (2010) (177)
Dendritic cell longevity and T cell persistence is controlled by CD154‐CD40 interactions (2001) (175)
Chitin Recognition via Chitotriosidase Promotes Pathologic Type-2 Helper T Cell Responses to Cryptococcal Infection (2015) (174)
Visualization of the Genesis and Fate of Isotype-switched B Cells during a Primary Immune Response (2003) (170)
CD4+ T cell anergy prevents autoimmunity and generates regulatory T cell precursors (2015) (167)
CD4+ T cells that enter the draining lymph nodes after antigen injection participate in the primary response and become central–memory cells (2006) (162)
Preferential Accumulation of Antigen-specific Effector CD4 T Cells at an Antigen Injection Site Involves CD62E-dependent Migration but Not Local Proliferation (2003) (162)
Dendritic cell antigen presentation drives simultaneous cytokine production by effector and regulatory T cells in inflamed skin. (2009) (162)
An accessory cell-derived costimulatory signal acts independently of protein kinase C activation to allow T cell proliferation and prevent the induction of unresponsiveness. (1989) (147)
The CD28 ligand, B7, enhances IL-2 production by providing a costimulatory signal to T cells. (1992) (143)
Neuroantigen-specific Th2 cells are inefficient suppressors of experimental autoimmune encephalomyelitis induced by effector Th1 cells. (1995) (141)
Defective transcription of the IL-2 gene is associated with impaired expression of c-Fos, FosB, and JunB in anergic T helper 1 cells. (1996) (140)
Tolerance is established in polyclonal CD4+ T cells by distinct mechanisms, according to self-peptide expression patterns (2016) (139)
Self-reactive B lymphocytes overexpressing Bcl-xL escape negative selection and are tolerized by clonal anergy and receptor editing. (1998) (137)
T cell receptor cross-reactivity between similar foreign and self peptides influences naive cell population size and autoimmunity. (2015) (135)
The transcription factor KLF2 restrains CD4+ T follicular helper cell differentiation (2015) (129)
TCR signal quantity and quality in CD4+ T cell differentiation. (2014) (127)
Prevention of Peripheral Tolerance by a Dendritic Cell Growth Factor: Flt3 Ligand as an Adjuvant (1998) (125)
Deletion and anergy of polyclonal B cells specific for ubiquitous membrane-bound self-antigen (2012) (125)
Molecular mechanisms underlying functional T-cell unresponsiveness. (1995) (120)
T-cell clonal anergy. (1997) (115)
Apoptosis and antigen affinity limit effector cell differentiation of a single naïve B cell (2015) (107)
In Situ Analysis Reveals Physical Interactions Between CD11b+ Dendritic Cells and Antigen-Specific CD4 T Cells After Subcutaneous Injection of Antigen1 (2002) (107)
Quantitative impact of thymic selection on Foxp3+ and Foxp3− subsets of self-peptide/MHC class II-specific CD4+ T cells (2011) (106)
Surface proteins involved in T cell costimulation (1994) (102)
Detection of an autoreactive T-cell population within the polyclonal repertoire that undergoes distinct autoimmune regulator (Aire)-mediated selection (2012) (97)
In Vivo Assessment of the Relative Contributions of Deletion, Anergy, and Editing to B Cell Self-Tolerance1 (2005) (94)
Robust Antigen Specific Th17 T Cell Response to Group A Streptococcus Is Dependent on IL-6 and Intranasal Route of Infection (2011) (94)
Cutting Edge: In Vivo Identification of TCR Redistribution and Polarized IL-2 Production by Naive CD4 T Cells1 (2001) (92)
Single-cell analysis of signal transduction in CD4 T cells stimulated by antigen in vivo (2001) (90)
In vivo antigen presentation. (2004) (88)
Temporal Expression of Bacterial Proteins Instructs Host CD4 T Cell Expansion and Th17 Development (2012) (84)
Regulatory CD4+ T Cells Recognize Major Histocompatibility Complex Class II Molecule-Restricted Peptide Epitopes of Apolipoprotein B. (2018) (83)
Arthritogenic Self-Reactive CD4+ T Cells Acquire an FR4hiCD73hi Anergic State in the Presence of Foxp3+ Regulatory T Cells (2012) (83)
Antigen-Experienced CD4 T Cells Display a Reduced Capacity for Clonal Expansion In Vivo That Is Imposed by Factors Present in the Immune Host1 (2000) (77)
Cutting Edge: Nucleocapsid Vaccine Elicits Spike-Independent SARS-CoV-2 Protective Immunity (2021) (73)
Cutting edge: antigen-dependent regulation of telomerase activity in murine T cells. (1998) (73)
Antigen presentation by resting B cells. Effectiveness at inducing T cell proliferation is determined by costimulatory signals, not T cell receptor occupancy. (1990) (73)
Cyclosporin A inhibits positive selection and delays negative selection in alpha beta TCR transgenic mice. (1994) (69)
CD4+ T Cells: Guardians of the Phagosome (2014) (69)
Heterogeneity in the differentiation and function of memory B cells. (2012) (68)
CD4+ T Cell Persistence and Function after Infection Are Maintained by Low-Level Peptide:MHC Class II Presentation (2013) (67)
Effect of gamma radiation on resting B lymphocytes. II. Functional characterization of the antigen-presentation defect. (1988) (66)
Induction and maintenance of anergy in mature T cells. (1991) (64)
PD-1, but Not PD-L1, Expressed by Islet-Reactive CD4+ T Cells Suppresses Infiltration of the Pancreas During Type 1 Diabetes (2013) (64)
In vivo effects of GK1.5 (anti-L3T4a) monoclonal antibody on induction and expression of delayed-type hypersensitivity. (1985) (60)
Peripheral immune tolerance blocks clonal expansion but fails to prevent the differentiation of Th1 cells. (1998) (58)
Most microbe-specific naïve CD4+ T cells produce memory cells during infection (2016) (58)
Identification of Natural Regulatory T Cell Epitopes Reveals Convergence on a Dominant Autoantigen (2017) (58)
Immature human monocyte-derived dendritic cells migrate rapidly to draining lymph nodes after intradermal injection for melanoma immunotherapy. (1999) (56)
Indirect Minor Histocompatibility Antigen Presentation by Allograft Recipient Cells in the Draining Lymph Node Leads to the Activation and Clonal Expansion of CD4+ T Cells That Cause Obliterative Airways Disease1 (2004) (56)
Salmonella Persist in Activated Macrophages in T Cell‐Sparse Granulomas but Are Contained by Surrounding CXCR3 Ligand‐Positioned Th1 Cells (2018) (53)
Naive B Cells with High‐Avidity Germline‐Encoded Antigen Receptors Produce Persistent IgM+ and Transient IgG+ Memory B Cells (2018) (53)
CD4+ memory T cell survival. (2011) (52)
CCR6-dependent recruitment of blood phagocytes is necessary for rapid CD4 T cell responses to local bacterial infection (2007) (50)
Generation of Th17 cells in response to intranasal infection requires TGF-β1 from dendritic cells and IL-6 from CD301b+ dendritic cells (2015) (49)
Positive selection optimizes the number and function of MHCII-restricted CD4+ T cell clones in the naive polyclonal repertoire (2009) (49)
Primary induction of CD4 T cell responses in nasal associated lymphoid tissue during group A streptococcal infection (2004) (46)
High-affinity memory B cells induced by SARS-CoV-2 infection produce more plasmablasts and atypical memory B cells than those primed by mRNA vaccines (2021) (46)
Calnexin induces expansion of antigen-specific CD4(+) T cells that confer immunity to fungal ascomycetes via conserved epitopes. (2015) (46)
An intracellular calcium increase and protein kinase C activation fail to initiate T cell proliferation in the absence of a costimulatory signal. (1990) (44)
Accessory cell-derived signals required for T cell activation (1993) (44)
CD4+CD25+Foxp3+ Regulatory T Cells Optimize Diversity of the Conventional T Cell Repertoire during Reconstitution from Lymphopenia (2010) (42)
A Protease-Dependent Mechanism for Initiating T-Dependent B Cell Responses to Large Particulate Antigens (2010) (42)
Cell and receptor requirements for streptococcal pyrogenic exotoxin T-cell mitogenicity (1991) (41)
Negative Selection and Peptide Chemistry Determine the Size of Naive Foreign Peptide–MHC Class II-Specific CD4+ T Cell Populations (2010) (41)
Cutting Edge: Identification of Autoreactive CD4+ and CD8+ T Cell Subsets Resistant to PD-1 Pathway Blockade (2015) (41)
Cutting Edge: Type 1 Diabetes Occurs despite Robust Anergy among Endogenous Insulin-Specific CD4 T Cells in NOD Mice (2013) (41)
IN VIVO ACTIVATION OF ANTIGEN-SPECIFIC (2001) (41)
The transcription factors Thpok and LRF are necessary and partly redundant for T helper cell differentiation. (2012) (41)
IL‐1 acts on antigen‐presenting cells to enhance the in vivo proliferation of antigen‐stimulated naive CD4 T cells via a CD28‐dependent mechanism that does not involve increased expression of CD28 ligands (2004) (40)
Regulatory CD4+ T Cells Recognize MHC-II-Restricted Peptide Epitopes of Apolipoprotein B (2018) (38)
Nucleocapsid vaccine elicits spike-independent SARS-CoV-2 protective immunity (2021) (38)
Monocytes provide a novel costimulatory signal to T cells that is not mediated by the CD28/B7 interaction. (1994) (37)
Increased Effector Memory Insulin-Specific CD4+ T Cells Correlate With Insulin Autoantibodies in Patients With Recent-Onset Type 1 Diabetes (2017) (36)
The role of anergy in peripheral T cell unresponsiveness. (1994) (34)
TCR Affinity Biases Th Cell Differentiation by Regulating CD25, Eef1e1, and Gbp2 (2019) (34)
Tracking antigen‐specific CD4+ T cells throughout the course of chronic Leishmania major infection in resistant mice (2013) (34)
Clonal Expansion of Antigen-Specific CD4 T Cells following Infection with Salmonella typhimurium Is Similar in Susceptible (Itys) and Resistant (Ityr) BALB/c Mice (1999) (33)
Do Memory B Cells Form Secondary Germinal Centers? It Depends. (2018) (32)
Molecular requirements for T cell activation by the staphylococcal toxic shock syndrome toxin-1. (1990) (31)
CD28 Promotes CD4+ T Cell Clonal Expansion during Infection Independently of Its YMNM and PYAP Motifs (2012) (30)
Accumulation of Sequence-specific RNA-binding Proteins in the Cytosol of Activated T Cells Undergoing RNA Degradation and Apoptosis (*) (1995) (30)
Proliferating CD4+ T Cells Undergo Immediate Growth Arrest upon Cessation of TCR Signaling In Vivo1 (2008) (30)
CD25+Foxp3+ Regulatory T Cells Facilitate CD4+ T Cell Clonal Anergy Induction during the Recovery from Lymphopenia1 (2006) (30)
A monoclonal antibody specific for a cytochrome c T cell stimulatory peptide inhibits T cell responses and affects the way the peptide associates with antigen‐presenting cells (1991) (30)
Memory and anergy: challenges to traditional models of T lymphocyte differentiation (1992) (30)
Polyclonal CD4+ T cell tolerance is established by distinct mechanisms, according to self-peptide expression patterns (2015) (29)
Hapten-specific naïve B cells are biomarkers of vaccine efficacy against drugs of abuse. (2014) (28)
Novel virus-like nanoparticle vaccine effectively protects animal model from SARS-CoV-2 infection (2021) (28)
Revealing the in vivo behavior of CD4+ T cells specific for an antigen expressed in Escherichia coli. (1998) (27)
TCR ITAM multiplicity is required for the generation of follicular helper T-cells (2015) (26)
Cutting Edge: Mouse SARS-CoV-2 Epitope Reveals Infection and Vaccine-Elicited CD8 T Cell Responses (2021) (25)
Whole-body analysis of T cell responses. (2003) (25)
Modulating the quantity of HIV Env-specific CD4 T cell help promotes rare B cell responses in germinal centers (2020) (24)
Adaptive Immunity to Leukemia Is Inhibited by Cross-Reactive Induced Regulatory T Cells (2015) (24)
Efficient generation of monoclonal antibodies against peptide in the context of MHCII using magnetic enrichment (2016) (23)
Murine lymphotactin: gene structure, post-translational modification and inhibition of expression by CD28 costimulation. (1997) (22)
IL-2 secretion and T cell clonal anergy are induced by distinct biochemical pathways. (1991) (22)
SARS‐CoV‐2 neutralization and serology testing of COVID‐19 convalescent plasma from donors with nonsevere disease (2020) (22)
A Thpok-Directed Transcriptional Circuitry Promotes Bcl6 and Maf Expression to Orchestrate T Follicular Helper Differentiation. (2019) (22)
Cutting Edge: Bcl6-Interacting Corepressor Contributes to Germinal Center T Follicular Helper Cell Formation and B Cell Helper Function (2015) (22)
Migration and accumulation of effector CD4+ T cells in nonlymphoid tissues. (2007) (21)
Self-reactive T cells are present in the peripheral lymphoid tissues of cyclosporin A-treated mice. (1992) (21)
Co-stimulatory functions of antigen-presenting cells. (1992) (20)
Cutting Edge: Adenosine A2a Receptor Signals Inhibit Germinal Center T Follicular Helper Cell Differentiation during the Primary Response to Vaccination (2017) (20)
Anti-CD3 epsilon F(ab')2 fragments inhibit T cell expansion in vivo during graft-versus-host disease or the primary immune response to nominal antigen. (1997) (19)
Identification of MHC-Bound Peptides from Dendritic Cells Infected with Salmonella enterica Strain SL1344: Implications for a Nontyphoidal Salmonella Vaccine. (2017) (19)
Initial determination of COVID-19 seroprevalence among outpatients and healthcare workers in Minnesota using a novel SARS-CoV-2 total antibody ELISA (2020) (18)
Inventories of naive and tolerant mouse CD4 T cell repertoires reveal a hierarchy of deleted and diverted T cell receptors (2019) (18)
Flow Cytometric Analysis of T Cell Receptor Signal Transduction (2002) (16)
Kinetics of CD 4 1 T cell repopulation of lymphoid tissues after treatment of HIV-1 infection (1998) (15)
BCL6 corepressor contributes to Th17 cell formation by inhibiting Th17 fate suppressors (2019) (15)
Many Th Cell Subsets Have Fas Ligand–Dependent Cytotoxic Potential (2018) (15)
Autoimmunity: When self-tolerance breaks down (1997) (14)
Isolation and characterization of an I-A-restricted T cell clone with dual specificity for poly(Glu60Ala30Tyr10) (GAT) and Mlsa,dl. (1984) (14)
Cutting Edge: T Cell–Dependent Plasmablasts Form in the Absence of Single Differentiated CD4+ T Cell Subsets (2018) (13)
Two sequential activation modules control the differentiation of protective T helper-1 (Th1) cells. (2021) (13)
Studying Immunological Tolerance by Physically Monitoring Antigen‐specific T Cells in Vivo a (1996) (13)
Enrichment and Quantification of Epitope-specific CD4+ T Lymphocytes using Ferromagnetic Iron-gold and Nickel Nanowires (2018) (13)
Costimulating factors and signals relevant for antigen presenting cell function. (1993) (13)
Chrysalis: A New Method for High-Throughput Histo-Cytometry Analysis of Images and Movies (2018) (11)
Intranasal Nanoparticle Vaccination Elicits a Persistent, Polyfunctional CD4 T Cell Response in the Murine Lung Specific for a Highly Conserved Influenza Virus Antigen That Is Sufficient To Mediate Protection from Influenza Virus Challenge (2021) (11)
Antigen-specific CD4+ T cells that survive after the induction of peripheral tolerance possess an intrinsic lymphokine production defect. (1998) (11)
Accessory Cell‐Derived Costimulatory Signals Regulate T Cell Proliferation a (1991) (10)
Immune tolerance of food is mediated by layers of CD4+ T cell dysfunction (2022) (9)
Immunoregulatory Pathways in Adult Responder Mice (1984) (8)
The Neonatal CD4+ T Cell Response to a Single Epitope Varies in Genetically Identical Mice (2015) (7)
Peptide:MHCII Tetramer‐Based Cell Enrichment for the Study of Epitope‐Specific CD4+ T Cells (2019) (7)
VISUALIZATION OF ANTIGEN-SPECIFIC CD4+ T CELL-B CELL INTERACTION DURING A PRIMARY IMMUNE RESPONSE IN VIVO (1998) (7)
MHC class II tetramers engineered for enhanced binding to CD4 improve detection of antigen-specific T cells (2021) (7)
Detection of suppressor cells and suppressor factors for delayed-type hypersensitivity responses (1986) (6)
Immunoregulatory pathways in adult responder mice. III. Establishment of a GAT-specific suppressor T cell clone from GAT-tolerant responders which afferently regulates DTH responses. (1985) (6)
Costimulatory Interactions Determine Proliferation Versus Induction of Clonal Anergy During Type I CD4 + T-Cell Stimulation (1989) (6)
Route of self-amplifying mRNA vaccination modulates the establishment of pulmonary resident memory CD8 and CD4 T cells (2022) (6)
CD154+ Graft Antigen‐Specific CD4+ T Cells are Sufficient for Chronic Rejection of Minor Antigen Incompatible Heart Grafts (2006) (6)
Pillars article: antigen presentation by chemically modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo. J. Exp. Med. 1987. 165: 302-319. (2009) (5)
The human T‐cell repertoire grows up (2015) (5)
A role for inflammatory cytokines in the productive activation of antigen-specific CD4+ T-cells. (1998) (5)
Suppressor T cell circuits in contact sensitivity. III. A monoclonal T cell hybrid-derived suppressor factor specifically suppresses local DTH transfer by a DNP-specific T cell clone. (1986) (4)
Antigen-Specific CD4+ T Cells Exhibit Distinct Kinetic and Phenotypic Patterns During Primary and Secondary Responses to Infection (2020) (4)
Kinetics of CD4 1 T cell repopulation of lymphoid tissues after treatment of HIV-1 infection (1998) (4)
SARS-CoV-2 neutralization and serology testing of COVID-19 convalescent plasma from donors with non-severe disease (2020) (4)
CD4+ Memory T-Cell Formation during Type 1 Immune Responses. (2021) (4)
Imaging the immune system (2008) (4)
Erratum to T Cell Receptor Cross-Reactivity between Similar Foreign and Self Peptides Influences Naive Cell Population Size and Autoimmunity (Immunity 42, 95-107, 2015) (2015) (4)
Immunoregulatory pathways in adult responder mice. II. Regulation of delayed-type hypersensitivity responses by GAT-specific suppressor factors present in GAT-tolerant adult responder mice. (1985) (3)
On the trail of arthritogenic T cells. (2011) (3)
Cutting Edge: Allograft Rejection Is Associated with Weak T Cell Responses to Many Different Graft Leukocyte-Derived Peptides (2018) (2)
The In Vivo Response of Naive CD4+ T Cells (2014) (2)
Response to Comment on “The Role of Naive T Cell Precursor Frequency and Recruitment in Dictating Immune Response Magnitude” (2013) (2)
Regulatory T Cells: A Crisis Averted. (2016) (2)
A single amino acid substitution in a cytochrome c T cell stimulatory peptide changes the MHC restriction element from one isotype (I-Ak) to another (I-Ek). (1993) (2)
Adjuvants and the Initiation of T-Cell Responses (2006) (2)
Dirty Mice Have Altered Influenza A Virus Clearance And Lesions Compared To SPF Mice: A Proposed Model For Study Of Vaccine Response In Humans (2020) (1)
In vitro and in vivo correlates of hybrid tumor resistance. (1987) (1)
Mechanisms of genetic control of immune responses (1986) (1)
Activation-dependent regulation of telomerase activity in murine T and B cells (1998) (1)
Evaluating Influenza A virus vaccines in a dirty mouse model better mimics the human immune response (2020) (1)
Pillars article: visualization of Peptide-specific T cell immunity and peripheral tolerance induction in vivo. Immunity. 1994. 1: 327-339. (2013) (1)
Subcutaneous Injection of Antigen Antigen-Specific CD 4 T Cells After Dendritic Cells and + Between CD 11 b In Situ Analysis Reveals Physical Interactions and (2002) (1)
Specific patterns of self-antigen expression determine the mechanisms by which polyclonal self-reactive CD4+ T cells are tolerized. (2016) (1)
Dissociation of Cellular and Humoral Immune Responsiveness to GAT (1983) (1)
Boosting corrects a memory B cell defect in SARS-CoV-2 mRNA–vaccinated patients with inflammatory bowel disease (2022) (1)
Large Particulate Antigens Initiating T-Dependent B Cell Responses to A Protease-Dependent Mechanism for Rooijen and (2010) (1)
Bcl6 interacting corepressor contributes to CD4+ T helper 17 cell formation by repressing CD27 and Foxo1 signaling (2018) (0)
Understanding MHCII-restricted T cell receptor cross-reactivity to foreign peptides (P5011) (2013) (0)
IL-15 complex modulates the Plasmodium-specific CD4 T cell response in mice (2020) (0)
Surface antigens are rapidly separated from bacterium‐sized microspheres in the subcapsular sinus and acquired by antigen‐specific follicular B cells (2008) (0)
408 Inflammatory and Suppressive Graft Antigen-Specific CD4+ T Cells Co-Exist in Heart Allografts (2011) (0)
Epitope-specific CD4+ T cell response to Group A Streptococcal infection (99.27) (2011) (0)
Characterization of naive CD4+ T cells with specificity to self-antigen (137.21) (2009) (0)
T H What?...Simplifying Adaptive Immune Cell Populations (2016) (0)
Repertoire / Diversity (T and B) (SY3-3) Chairpersons: Masamichi Muramatsu, Kristin Hogquist (2010) (0)
The naïve CD8+ T cell pool contains a variable frequency of memory phenotype T cells bearing the signature of homeostatic expansion (2008) (0)
This information is current as TCR Signaling In Vivo Immediate Growth Arrest upon Cessation of T Cells Undergo + Proliferating CD 4 Catron (2007) (0)
Development of vaccination approaches that reverse leukemia-induced tolerance and reduce leukemic burden (TUM9P.1020) (2015) (0)
Importance of TCR ITAM multiplicity in the establishment of central tolerance (36.48) (2010) (0)
Analysis of the formation of antigen-specific memory CD4+ T cell populations derived from single naïve precursors (LYM3P.731) (2014) (0)
Route of infection determines T helper-1 versus T helper-17 subset differentiation (46.9) (2009) (0)
Implications of T cell receptor cross-reactivity on the CD4+ T cell repertoire (APP3P.111) (2015) (0)
Analysis of the differentiation of single antigen-specific B cells early in the primary response (P1477) (2013) (0)
MHC class II tetramers identify apolipoprotein B-specific CD4 T cells in mice and humans (2017) (0)
Localized p:MHCII presentation maintains CD4+ T cell stability and avoids exhaustion (163.19) (2012) (0)
Generation of IgA plasma cells during a secondary response in the absence of IgA memory B cells (LYM6P.800) (2014) (0)
Faculty Opinions recommendation of Dynamic imaging of T cell-dendritic cell interactions in lymph nodes. (2002) (0)
Adenosine 2A Receptor Promotes Tolerance by Reducing Germinal Center Follicular Helper T cells and Pathogenic Class-Switched B cells (2016) (0)
Abstract 16015: Loss of Protective Autoimmunity in Atherosclerosis (2016) (0)
T cell cross-reactivity to self peptide:MHCII shapes the foreign peptide: MHCII-specific CD4+ T cell repertoire (APP2P.112) (2014) (0)
Chapter 6 – Antigen-Presenting Cell Regulation of T Cell Activation (1994) (0)
In vivo and in vitro correlates of F1 hybrid resistance to a murine squamous cell carcinoma, TDM4 (1985) (0)
Single-cell transcriptomes and T cell receptors of vaccine-expanded apolipoprotein B-specific T cells (2023) (0)
Overcoming Leukemia-Induced Immune Suppression in BCR-ABL+ Acute Lymphoblastic Leukemia (2017) (0)
CD8+ T Cells Signal for Activation of Naive CD4+ and Inflammatory Cytokines Provide a Third (2013) (0)
Identification of MHC bound peptides from murine bone marrow derived dendritic cells infected with Salmonella (VAC9P.1108) (2015) (0)
The generation of TH17 cells in response to bacterial infection requires IL-6 and dendritic cell-produced TGF-β1, but not IL-1 (163.14) (2012) (0)
The murine immune response to the male‐specific antigen mouse testicular cytochrome c (1993) (0)
The role of cytotoxic CD4+ T cells in controlling Salmonella. (MPF6P.741) (2014) (0)
Tracking immune responses in vivo (2005) (0)
Novel immunological tools to investigate CD4+ T cell activation in the canine species (2022) (0)
Robust Th17 response to intranasal group A streptococcal infection requires IL-6 produced by CD301b+CD11b+CD103- migratory dendritic cells (MUC2P.937) (2015) (0)
During Natural Infection with T Cell Responses + Characterization of CD4 (0)
Immune Host Vivo That Is Imposed by Factors Present in Reduced Capacity for Clonal Expansion In Antigen-Experienced CD 4 T Cells Display a (2000) (0)
Intracellular Salmonella enterica infection is controlled in mononuclear phagocytes that attract CXCR3+ Th1 cells in vivo and persists in those that do not (2018) (0)
CD28 signals through tyrosine residues in its cytoplasmic tail to promote CD4+ T cell clonal expansion during infection (2016) (0)
This information is current as during the Recovery from Lymphopenia T Cell Clonal Anergy Induction + CD 4 Regulatory T Cells Facilitate + Foxp 3 + CD 25 and (2006) (0)
Insulin-Specific CD4 T Cells in NOD Mice despite Robust Anergy among Endogenous Cutting Edge: Type 1 Diabetes Occurs (2013) (0)
Erratum: Revealing the in vivo behavior of CD4+ T cells specific for an antigen expressed in Escherichia coli (Journal of Immunology (1998) 160 (3462-3470)) (1999) (0)
Identification of self-specific CD4+ T cell subsets resistant to PD-1 blockade (BA11P.130) (2015) (0)
146: IFN-γ production by graft antigen specific CD4+ T cells is not required for the development of intimal hyerplasia (2007) (0)
of Peripheral Tolerance Induction CD4+ T Cells Persist In Vivo Following Direct Evidence That Functionally Impaired (2013) (0)
Foreign antigen-specific Foxp3+ regulatory T cells expand with immunization and limit Th1 polarization by Foxp3− conventional cells specific for the same antigen (2018) (0)
Abstract 351: MHC-II Tetramer-based Isolation of Atherosclerosis Autoantigen-specific T Cells (2016) (0)
The Transcription Factor K LF 2 Restrains CD 4 + T Follicular Helper Cell Differentiation Highlights (2015) (0)
Delayed gratification: A program of intimal hyperplasia progresses even as graft antigen-specific CD4+ T cells subside (2007) (0)
Requirement for PD-1 in the induction and maintenance of tolerance differs depending on tolerogenic stimulus (BA8P.118) (2014) (0)
mitogenicity.pyrogenic exotoxin T-cell Cell and receptor requirements for (2013) (0)
Each naïve B cell within a polyclonal repertoire produces a different frequency and pattern of effector cells (LYM6P.769) (2014) (0)
249 Antigen-specific T cells are activated at early times following antigen inhalation (1996) (0)
Regulation of adhesion molecule expression by t cell activation in vivo (1996) (0)
NK cell-derived IL-10 enhances Plasmodium-specific CD4+ Tfh differentiation and IL-27 production in mice (2022) (0)
Phenotypic similarities of anergic and regulatory T cells (2008) (0)
T Cells + and CD 8 + Signal for Activation of Naive CD 4 Inflammatory Cytokines Provide a Third (1999) (0)
DiseaseCells That Cause Obliterative Airways T + Activation and Clonal Expansion of CD4 the Draining Lymph Node Leads to the Presentation by Allograft Recipient Cells in Indirect Minor Histocompatibility Antigen (2004) (0)
CD28 enhances in vivo clonal expansion by CD4+ T cells without increasing sensitivity to antigen (2008) (0)
Peptide:MHC Class II Presentation Infection Are Maintained by Low-Level T Cell Persistence and Function after + CD4 (2013) (0)
Oral administration of antigen mainly induces T helper lineage-negative CD200+ CTLA4+ anergic CD4+ T cells which tend to become regulatory T cells (2020) (0)
The generation of peptide: MHCII-specific TH17 cells in response to intranasal bacterial infection requires IL-6 and TGF-β1, produced from a distinct mucosal dendritic cell subset. (LYM3P.740) (2014) (0)
Immune Frequency and Recruitment in Dictating The Role of Naive T Cell Precursor (2012) (0)
Abstract 21: A Natural Repertoire of T Cells Recognizing ApoB-100 is Generated Early in Life and is Progressively Depleted During Atherosclerotic Disease (2016) (0)
Foreign epitope-specific regulatory T cells respond robustly to vaccination and limit Th1 differentiation by conventional T cells specific for the same epitope (2020) (0)
Phycoerythrin Specific Mouse Antibodies (2018) (0)
Aire mediates peptide epitope-specific thymic deletion of self reactive T cells to prevent autoimmune uveitis (148.3) (2011) (0)
Pathogen-specific regulatory T cells impair protective immunity in tuberculosis (129.25) (2009) (0)
Polyclonal anergic CD4 T cells give rise to pathogenic TH1 and suppressive regulatory T cells during lymphopenia. (P1024) (2013) (0)
CD4+ T cell control of Salmonella infection and persistence is dependent on different macrophage subsets (2017) (0)
BY CHEMICALLY MODIFIED SPLENOCYTES INDUCES ANTIGEN-SPECIFIC T CELL UNRESPONSIVENESS IN VITRO AND IN VIVO (2003) (0)
Enrichment and Quantification of Epitope-specific CD4+ T Lymphocytes using Ferromagnetic Iron-gold and Nickel Nanowires (2018) (0)
Oral administration of a peptide antigen with the cholera toxin adjuvant induces Th17 rather than Th2 cells (2021) (0)
Peripheral Tolerance T Cells Persist In Vivo Following Induction of + Direct Evidence That Functionally Impaired CD 4 Khoruts and (1998) (0)
Induction and characterization of a poly(glu60 a30tyr10) (gat)-specific t suppressor hybridoma product from gat-responders. Abstr. (1983) (0)
Mechanisms of genetic control of immune responses. II. Nonresponsiveness in BALB/c GT-specific cell-mediated immune responses does not correlate with the absence of functional T cells or the induction of suppressor T cells. (1986) (0)
Self-tolerance in the polyclonal CD4+ T cell repertoire (BA8P.132) (2014) (0)
Detection of Directly Alloreactive Graft Antigen-Specific CD4+ T Cells in Peripheral Blood (2022) (0)
Regulatory T Cells + the Presence of Foxp3 Anergic State in hi CD73 hi Acquire an FR4 T Cells + Arthritogenic Self-Reactive CD4 (2011) (0)
Abstract 44: Failure of Protective Autoimmunity in Mouse and Human Atherosclerosis (2017) (0)
Identification of PRRSV cross-neutralizing memory B cells (VIR7P.1062) (2014) (0)
Toward a general model of CD4+ T cell subset specification and memory cell formation. (2023) (0)
the Recovery from Lymphopenia during CD4+ T Cell Clonal Anergy Induction CD25+Foxp3+ Regulatory T Cells Facilitate (2013) (0)
Leo Lefrançois, Jr., Ph.D. (AAI ’84) 1956–2013 (2013) (0)
TCR affinity influences helper T cell differentiation by biasing dendritic cell interactions (2018) (0)

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