Marco Marra
#24,615
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Canadian geneticist
Marco Marra's AcademicInfluence.com Rankings
Marco Marrabiology Degrees
Biology
#1724
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Historical Rank
Genetics
#336
World Rank
#395
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Biology
Marco Marra's Degrees
- PhD Genetics University of British Columbia
- Bachelors Biochemistry University of British Columbia
Why Is Marco Marra Influential?
(Suggest an Edit or Addition)According to Wikipedia, Marco A. Marra is a Distinguished Scientist and Director of Canada's Michael Smith Genome Sciences Centre at the BC Cancer Research Centre and Professor of Medical Genetics at the University of British Columbia . He also serves as UBC Canada Research Chair in Genome Science for the Canadian Institutes of Health Research and is an inductee in the Canadian Medical Hall of Fame. Marra has been instrumental in bringing genome science to Canada by demonstrating the pivotal role that genomics can play in human health and disease research.
Marco Marra's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Initial sequencing and analysis of the human genome. (2001) (15222)
- Circos: an information aesthetic for comparative genomics. (2009) (7952)
- Comprehensive molecular portraits of human breast tumors (2012) (7791)
- Comprehensive molecular characterization of human colon and rectal cancer (2012) (6141)
- Integrative analysis of 111 reference human epigenomes (2015) (4979)
- Comprehensive molecular characterization of gastric adenocarcinoma (2014) (4496)
- Comprehensive molecular profiling of lung adenocarcinoma (2014) (4095)
- Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia. (2013) (3821)
- Integrated genomic characterization of endometrial carcinoma (2013) (3708)
- The Somatic Genomic Landscape of Glioblastoma (2013) (3693)
- Comprehensive genomic characterization of squamous cell lung cancers (2012) (2998)
- Comprehensive genomic characterization of head and neck squamous cell carcinomas (2015) (2860)
- The Immune Landscape of Cancer (2018) (2766)
- Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas. (2015) (2211)
- The ENCODE (ENCyclopedia Of DNA Elements) Project (2004) (2194)
- Genomic Classification of Cutaneous Melanoma (2015) (2143)
- The Molecular Taxonomy of Primary Prostate Cancer (2015) (2116)
- The Genome Sequence of the SARS-Associated Coronavirus (2003) (2063)
- Genome sequence of the Brown Norway rat yields insights into mammalian evolution (2004) (2053)
- Integrated Genomic Characterization of Papillary Thyroid Carcinoma (2014) (2007)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences (2002) (1846)
- International network of cancer genome projects (2010) (1839)
- The clonal and mutational evolution spectrum of primary triple-negative breast cancers (2012) (1807)
- Comprehensive molecular characterization of urothelial bladder carcinoma (2014) (1748)
- Comprehensive molecular characterization of clear cell renal cell carcinoma (2013) (1724)
- The NIH Roadmap Epigenomics Mapping Consortium (2010) (1680)
- Oncogenic Signaling Pathways in The Cancer Genome Atlas (2018) (1646)
- Conserved Role of Intragenic DNA Methylation in Regulating Alternative Promoters (2010) (1601)
- Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma (2017) (1514)
- Frequent mutation of histone modifying genes in non-Hodgkin lymphoma (2011) (1502)
- Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma (2016) (1474)
- ARID1A mutations in endometriosis-associated ovarian carcinomas. (2010) (1450)
- Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer (2017) (1446)
- Genome-wide profiles of STAT1 DNA association using chromatin immunoprecipitation and massively parallel sequencing (2007) (1432)
- Comprehensive Characterization of Cancer Driver Genes and Mutations (2018) (1360)
- The Genome of the Kinetoplastid Parasite, Leishmania major (2005) (1355)
- Comprehensive Molecular Portraits of Invasive Lobular Breast Cancer (2015) (1332)
- Evolutionary and Biomedical Insights from the Rhesus Macaque Genome (2007) (1309)
- Applications of next-generation sequencing technologies in functional genomics. (2008) (1200)
- Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution (2009) (1115)
- Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (2008) (1105)
- Integrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma. (2017) (1092)
- The Genome of the Sea Urchin Strongylocentrotus purpuratus (2006) (1056)
- The Genome Sequence of Caenorhabditis briggsae: A Platform for Comparative Genomics (2003) (972)
- Mutational Analysis Reveals the Origin and Therapy-Driven Evolution of Recurrent Glioma (2014) (954)
- The genetic landscape of high-risk neuroblastoma (2013) (938)
- De novo assembly and analysis of RNA-seq data (2010) (934)
- Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma. (2016) (931)
- Somatic mutation of EZH2 (Y641) in Follicular and Diffuse Large B-cell Lymphomas of Germinal Center Origin (2010) (780)
- Integrated genomic and molecular characterization of cervical cancer (2017) (762)
- Subgroup-specific structural variation across 1,000 medulloblastoma genomes (2012) (760)
- Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences (2007) (715)
- The Genome of the Basidiomycetous Yeast and Human Pathogen Cryptococcus neoformans (2005) (702)
- A tiling resolution DNA microarray with complete coverage of the human genome (2004) (680)
- Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications (2010) (673)
- Genetic alterations activating kinase and cytokine receptor signaling in high-risk acute lymphoblastic leukemia. (2012) (661)
- Mutation of FOXL2 in granulosa-cell tumors of the ovary. (2009) (661)
- The whole-genome landscape of medulloblastoma subtypes (2017) (658)
- The complete genome of Rhodococcus sp. RHA1 provides insights into a catabolic powerhouse (2006) (635)
- Identification of miR-145 and miR-146a as mediators of the 5q– syndrome phenotype (2010) (635)
- Comprehensive and Integrated Genomic Characterization of Adult Soft Tissue Sarcomas (2017) (577)
- Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation. (2011) (573)
- Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution (2014) (566)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (2004) (565)
- MHC class II transactivator CIITA is a recurrent gene fusion partner in lymphoid cancers (2011) (554)
- deFuse: An Algorithm for Gene Fusion Discovery in Tumor RNA-Seq Data (2011) (549)
- Applications of new sequencing technologies for transcriptome analysis. (2009) (527)
- Epigenomic alterations define lethal CIMP-positive ependymomas of infancy (2014) (507)
- Pathogenic Germline Variants in 10,389 Adult Cancers (2018) (501)
- Generation and analysis of 280,000 human expressed sequence tags. (1996) (491)
- Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients (2018) (471)
- Profiling the HeLa S3 transcriptome using randomly primed cDNA and massively parallel short-read sequencing. (2008) (461)
- A public database for gene expression in human cancers. (1999) (447)
- De novo transcriptome assembly with ABySS (2009) (426)
- The DNA sequence of human chromosome 7 (2003) (425)
- High-throughput microfluidic single-cell RT-qPCR (2011) (422)
- Genetic definition and sequence analysis of Arabidopsis centromeres. (1999) (420)
- The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions (2017) (416)
- High-Throughput In Vivo Analysis of Gene Expression in Caenorhabditis elegans (2007) (415)
- High throughput fingerprint analysis of large-insert clones. (1997) (410)
- Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana (1999) (403)
- Recurrent somatic DICER1 mutations in nonepithelial ovarian cancers. (2012) (396)
- Patterns of somatic structural variation in human cancer genomes (2020) (377)
- ATR-X Syndrome Protein Targets Tandem Repeats and Influences Allele-Specific Expression in a Size-Dependent Manner (2010) (377)
- Distinct evolutionary trajectories of primary high-grade serous ovarian cancers revealed through spatial mutational profiling (2013) (374)
- Mutational and structural analysis of diffuse large B-cell lymphoma using whole-genome sequencing. (2013) (365)
- The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery (2016) (360)
- Massively parallel sequencing: the next big thing in genetic medicine. (2009) (346)
- A physical map of the mouse genome (2002) (338)
- Development and application of a salmonid EST database and cDNA microarray: data mining and interspecific hybridization characteristics. (2004) (336)
- SKPs derive from hair follicle precursors and exhibit properties of adult dermal stem cells. (2009) (336)
- Transcriptome analysis of the normal human mammary cell commitment and differentiation process. (2008) (330)
- Whole transcriptome sequencing reveals recurrent NOTCH1 mutations in mantle cell lymphoma. (2012) (322)
- Alternative expression analysis by RNA sequencing (2010) (322)
- Next-generation tag sequencing for cancer gene expression profiling. (2009) (320)
- Rapid, reliable, and reproducible molecular sub-grouping of clinical medulloblastoma samples (2011) (318)
- Analysis of the Genome and Transcriptome of Cryptococcus neoformans var. grubii Reveals Complex RNA Expression and Microevolution Leading to Virulence Attenuation (2014) (316)
- Prospective isolation and molecular characterization of hematopoietic stem cells with durable self-renewal potential. (2009) (313)
- The Release 6 reference sequence of the Drosophila melanogaster genome (2015) (310)
- Gene expression profiling of cells, tissues, and developmental stages of the nematode C. elegans. (2003) (305)
- Oligonucleotide microarray analysis of genomic imbalance in children with mental retardation. (2006) (304)
- TITAN: inference of copy number architectures in clonal cell populations from tumor whole-genome sequence data (2014) (289)
- Functional Genomics of the Cilium, a Sensory Organelle (2005) (279)
- Concurrent CIC mutations, IDH mutations, and 1p/19q loss distinguish oligodendrogliomas from other cancers (2012) (273)
- Small cell carcinoma of the ovary, hypercalcemic type, displays frequent inactivating germline and somatic mutations in SMARCA4 (2014) (271)
- Divergent modes of clonal spread and intraperitoneal mixing in high-grade serous ovarian cancer (2016) (270)
- Driver and passenger mutations in cancer. (2015) (269)
- Divergent clonal selection dominates medulloblastoma at recurrence (2016) (266)
- Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution (2020) (258)
- Conifer defence against insects: microarray gene expression profiling of Sitka spruce (Picea sitchensis) induced by mechanical wounding or feeding by spruce budworms (Choristoneura occidentalis) or white pine weevils (Pissodes strobi) reveals large-scale changes of the host transcriptome. (2006) (247)
- Integrative analysis of genome-wide loss of heterozygosity and monoallelic expression at nucleotide resolution reveals disrupted pathways in triple-negative breast cancer (2012) (237)
- Changes in gene expression associated with developmental arrest and longevity in Caenorhabditis elegans. (2001) (237)
- Hive plots - rational approach to visualizing networks (2012) (237)
- Quiescent sox2(+) cells drive hierarchical growth and relapse in sonic hedgehog subgroup medulloblastoma. (2014) (235)
- Childhood Cerebellar Tumors Mirror Conserved Fetal Transcriptional Programs (2018) (232)
- Deep annotation of Drosophila melanogaster microRNAs yields insights into their processing, modification, and emergence. (2011) (232)
- Mutations in EZH2 cause Weaver syndrome. (2012) (230)
- 14-3-3 fusion oncogenes in high-grade endometrial stromal sarcoma (2012) (229)
- Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome. (2007) (221)
- SNVMix: predicting single nucleotide variants from next-generation sequencing of tumors (2010) (220)
- A SAGE Approach to Discovery of Genes Involved in Autophagic Cell Death (2003) (220)
- Analysis of long-lived C. elegans daf-2 mutants using serial analysis of gene expression. (2005) (215)
- Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort (2018) (212)
- Recurrent DGCR8, DROSHA, and SIX homeodomain mutations in favorable histology Wilms tumors. (2015) (210)
- Massively parallel sequencing of the polyadenylated transcriptome of C. elegans. (2009) (207)
- Genome and transcriptome analyses of the mountain pine beetle-fungal symbiont Grosmannia clavigera, a lodgepole pine pathogen (2011) (206)
- A Children's Oncology Group and TARGET Initiative Exploring the Genetic Landscape of Wilms Tumor (2017) (201)
- Comprehensive molecular characterization of mitochondrial genomes in human cancers (2017) (197)
- Analysis of the prostate cancer cell line LNCaP transcriptome using a sequencing-by-synthesis approach (2006) (196)
- Genome-wide relationship between histone H3 lysine 4 mono- and tri-methylation and transcription factor binding. (2008) (196)
- Novel Avian Influenza H7N3 Strain Outbreak, British Columbia (2004) (193)
- DNA hypomethylation within specific transposable element families associates with tissue-specific enhancer landscape (2013) (191)
- Genomics of hybrid poplar (Populus trichocarpa× deltoides) interacting with forest tent caterpillars (Malacosoma disstria): normalized and full‐length cDNA libraries, expressed sequence tags, and a cDNA microarray for the study of insect‐induced defences in poplar (2006) (189)
- Genomic consequences of aberrant DNA repair mechanisms stratify ovarian cancer histotypes (2017) (189)
- Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context (2018) (188)
- Gene discovery by EST sequencing in Toxoplasma gondii reveals sequences restricted to the Apicomplexa. (1998) (188)
- Evolution of an adenocarcinoma in response to selection by targeted kinase inhibitors (2010) (185)
- Double-Hit Gene Expression Signature Defines a Distinct Subgroup of Germinal Center B-Cell-Like Diffuse Large B-Cell Lymphoma. (2019) (184)
- In-depth characterization of the microRNA transcriptome in a leukemia progression model. (2008) (184)
- Genome Variation in Cryptococcus gattii, an Emerging Pathogen of Immunocompetent Hosts (2011) (184)
- The ELT-2 GATA-factor and the global regulation of transcription in the C. elegans intestine. (2007) (182)
- Genomic analyses identify recurrent MEF2D fusions in acute lymphoblastic leukaemia (2016) (181)
- JointSNVMix: a probabilistic model for accurate detection of somatic mutations in normal/tumour paired next-generation sequencing data (2012) (177)
- From sequence to molecular pathology, and a mechanism driving the neuroendocrine phenotype in prostate cancer (2012) (173)
- Comprehensive microRNA expression profiling of the hematopoietic hierarchy (2010) (171)
- The genetic basis and cell of origin of mixed phenotype acute leukaemia (2018) (171)
- The molecular signature and cis-regulatory architecture of a C. elegans gustatory neuron. (2007) (171)
- Recurrent somatic mutations of PTPN1 in primary mediastinal B cell lymphoma and Hodgkin lymphoma (2014) (170)
- De novo genome sequence assembly of a filamentous fungus using Sanger, 454 and Illumina sequence data (2009) (170)
- A Pan-BCL2 inhibitor renders bone-marrow-resident human leukemia stem cells sensitive to tyrosine kinase inhibition. (2013) (166)
- Histological Transformation and Progression in Follicular Lymphoma: A Clonal Evolution Study (2016) (165)
- Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma (2013) (164)
- Acquired TNFRSF14 mutations in follicular lymphoma are associated with worse prognosis. (2010) (164)
- Global analysis of in vivo Foxa2-binding sites in mouse adult liver using massively parallel sequencing (2008) (163)
- ADAR1 Activation Drives Leukemia Stem Cell Self-Renewal by Impairing Let-7 Biogenesis. (2016) (160)
- A complete BAC-based physical map of the Arabidopsis thaliana genome (1999) (159)
- Functional DNA methylation differences between tissues, cell types, and across individuals discovered using the M&M algorithm (2013) (158)
- Molecular and Genetic Characterization of MHC Deficiency Identifies EZH2 as Therapeutic Target for Enhancing Immune Recognition. (2019) (158)
- Whole-Genome Profiling of Mutagenesis in Caenorhabditis elegans (2010) (152)
- Feature-based classifiers for somatic mutation detection in tumour–normal paired sequencing data (2011) (151)
- ELT-2 is the predominant transcription factor controlling differentiation and function of the C. elegans intestine, from embryo to adult. (2009) (144)
- A patient with vertebral, cognitive and behavioural abnormalities and a de novo deletion of NRXN1α (2007) (143)
- MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing. (2010) (143)
- Epidermal growth factor receptor (EGFR) is transcriptionally induced by the Y-box binding protein-1 (YB-1) and can be inhibited with Iressa in basal-like breast cancer, providing a potential target for therapy (2007) (141)
- High-resolution profiling and discovery of planarian small RNAs (2009) (141)
- Notch initiates the endothelial-to-mesenchymal transition in the atrioventricular canal through autocrine activation of soluble guanylyl cyclase. (2011) (141)
- ADAR1 promotes malignant progenitor reprogramming in chronic myeloid leukemia (2012) (141)
- Expressed Sequence Tag Analysis of the Bradyzoite Stage of Toxoplasma gondii: Identification of Developmentally Regulated Genes (1998) (139)
- The Somatic Genomic Landscape of Glioblastoma (2014) (135)
- Large-scale profiling of microRNAs for The Cancer Genome Atlas (2015) (132)
- The completion of the Mammalian Gene Collection (MGC). (2009) (132)
- A high-resolution whole-genome cattle-human comparative map reveals details of mammalian chromosome evolution. (2005) (130)
- A mouse atlas of gene expression: large-scale digital gene-expression profiles from precisely defined developing C57BL/6J mouse tissues and cells. (2005) (130)
- A conifer genomics resource of 200,000 spruce (Picea spp.) ESTs and 6,464 high-quality, sequence-finished full-length cDNAs for Sitka spruce (Picea sitchensis) (2008) (129)
- A set of BAC clones spanning the human genome. (2004) (128)
- A map for sequence analysis of the Arabidopsis thaliana genome (1999) (128)
- BCL2 mutations in diffuse large B-cell lymphoma (2012) (127)
- Expressed sequence tags--ESTablishing bridges between genomes. (1998) (127)
- The Complete Sequence of a Heterochromatic Island from a Higher Eukaryote (2000) (127)
- Identification of GPC2 as an Oncoprotein and Candidate Immunotherapeutic Target in High-Risk Neuroblastoma. (2017) (124)
- Analysis of FOXO1 mutations in diffuse large B-cell lymphoma. (2013) (124)
- Cryptococcus neoformans Gene Expression during Experimental Cryptococcal Meningitis (2003) (123)
- ETV6-NTRK3 Is Expressed in a Subset of ALK-Negative Inflammatory Myofibroblastic Tumors (2016) (123)
- An encyclopedia of mouse genes (1999) (122)
- The E3 ubiquitin ligase UBR5 is recurrently mutated in mantle cell lymphoma. (2013) (122)
- Clonal Decomposition and DNA Replication States Defined by Scaled Single-Cell Genome Sequencing (2019) (121)
- MEF2 transcription factors: developmental regulators and emerging cancer genes (2015) (120)
- Genome-wide discovery of somatic coding and noncoding mutations in pediatric endemic and sporadic Burkitt lymphoma. (2019) (120)
- Identification of genes expressed in the hermaphrodite germ line of C. elegans using SAGE (2009) (119)
- Genome-wide identification of human microRNAs located in leukemia-associated genomic alterations. (2009) (119)
- BCL6 repression of EP300 in human diffuse large B cell lymphoma cells provides a basis for rational combinatorial therapy. (2010) (119)
- Multifocal endometriotic lesions associated with cancer are clonal and carry a high mutation burden (2015) (119)
- Homologous Recombination Deficiency and Platinum-Based Therapy Outcomes in Advanced Breast Cancer (2017) (118)
- Recurrent targets of aberrant somatic hypermutation in lymphoma (2012) (116)
- Locus co-occupancy, nucleosome positioning, and H3K4me1 regulate the functionality of FOXA2-, HNF4A-, and PDX1-bound loci in islets and liver. (2010) (114)
- Generation, annotation, analysis and database integration of 16,500 white spruce EST clusters (2005) (114)
- A physical map of the genome of Atlantic salmon, Salmo salar. (2005) (113)
- Cross-cancer profiling of molecular alterations within the human autophagy interaction network (2015) (112)
- Convergent Genesis of an Adult Neural Crest‐Like Dermal Stem Cell from Distinct Developmental Origins (2010) (111)
- Transferrin receptor 2 (TfR2) and HFE mutational analysis in non-C282Y iron overload: identification of a novel TfR2 mutation. (2002) (111)
- Differential expression of a novel ankyrin containing E3 ubiquitin-protein ligase, Hace1, in sporadic Wilms' tumor versus normal kidney. (2004) (110)
- Comprehensive analysis of mammalian miRNA* species and their role in myeloid cells. (2011) (110)
- Cancer genome-sequencing study design (2013) (108)
- Erratum: Initial sequencing and analysis of the human genome: International Human Genome Sequencing Consortium (Nature (2001) 409 (860-921)) (2001) (106)
- Temperature-regulated transcription in the pathogenic fungus Cryptococcus neoformans. (2002) (104)
- Identifying potential tumor markers and antigens by database mining and rapid expression screening. (2000) (103)
- Genetic profiling of MYC and BCL2 in diffuse large B-cell lymphoma determines cell-of-origin-specific clinical impact. (2017) (102)
- Molecular profiling of clinical tissues specimens: feasibility and applications. (2000) (102)
- Genome-Wide Profiles of Extra-cranial Malignant Rhabdoid Tumors Reveal Heterogeneity and Dysregulated Developmental Pathways. (2016) (102)
- Iron‐regulated transcription and capsule formation in the fungal pathogen Cryptococcus neoformans (2004) (101)
- An Integrated Strategy to Study Muscle Development and Myofilament Structure in Caenorhabditis elegans (2009) (101)
- Spatial heterogeneity in medulloblastoma (2017) (101)
- Molecular profiling of clinical tissue specimens: feasibility and applications. (2000) (100)
- Identification of ciliary and ciliopathy genes in Caenorhabditis elegans through comparative genomics (2006) (99)
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4 (2005) (98)
- Lessons learned from the application of whole-genome analysis to the treatment of patients with advanced cancers (2015) (98)
- Cell of origin in AML: susceptibility to MN1-induced transformation is regulated by the MEIS1/AbdB-like HOX protein complex. (2011) (96)
- Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. (2000) (94)
- Clonal expansion and epigenetic reprogramming following deletion or amplification of mutant IDH1 (2017) (93)
- Comprehensive miRNA sequence analysis reveals survival differences in diffuse large B-cell lymphoma patients (2015) (93)
- Impact of whole genome amplification on analysis of copy number variants (2008) (91)
- Interaction of Cyclin-Dependent Kinase 12/CrkRS with Cyclin K1 Is Required for the Phosphorylation of the C-Terminal Domain of RNA Polymerase II (2012) (90)
- Analysis of 4,664 high-quality sequence-finished poplar full-length cDNA clones and their utility for the discovery of genes responding to insect feeding (2008) (89)
- Erratum: Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles (Cell Reports (2017) 18(11) (2780–2794) (S2211124717302140) (10.1016/j.celrep.2017.02.033)) (2017) (88)
- Cell of origin of transformed follicular lymphoma. (2015) (88)
- Hippo Signaling Influences HNF4A and FOXA2 Enhancer Switching during Hepatocyte Differentiation (2014) (88)
- GLI2 inhibition abrogates human leukemia stem cell dormancy (2015) (87)
- A physical map of the bovine genome (2007) (86)
- Analysis of Normal Human Mammary Epigenomes Reveals Cell-Specific Active Enhancer States and Associated Transcription Factor Networks. (2016) (86)
- NRG1 Gene Fusions Are Recurrent, Clinically Actionable Gene Rearrangements in KRAS Wild-Type Pancreatic Ductal Adenocarcinoma (2019) (86)
- Altered Gene Expression along the Glycolysis–Cholesterol Synthesis Axis Is Associated with Outcome in Pancreatic Cancer (2019) (86)
- Comparison of medulloblastoma and normal neural transcriptomes identifies a restricted set of activated genes (2003) (86)
- Gradient of Developmental and Injury Response transcriptional states defines functional vulnerabilities underpinning glioblastoma heterogeneity (2021) (85)
- The Caenorhabditis elegans unc-60 gene encodes proteins homologous to a family of actin-binding proteins (1994) (84)
- LNCaP Atlas: Gene expression associated with in vivo progression to castration-recurrent prostate cancer (2010) (84)
- Assessment of SAGE in transcript identification. (2003) (84)
- Genome-wide discovery of somatic regulatory variants in diffuse large B-cell lymphoma (2018) (83)
- Sequencing and analysis of 10,967 full-length cDNA clones from Xenopus laevis and Xenopus tropicalis reveals post-tetraploidization transcriptome remodeling. (2006) (82)
- Identification of novel androgen-responsive genes by sequencing of LongSAGE libraries (2009) (82)
- Intermediate DNA methylation is a conserved signature of genome regulation (2015) (81)
- Novel Avian Influenza H7N3 Strain Outbreak (2004) (79)
- Novel deletions of 14q11.2 associated with developmental delay, cognitive impairment and similar minor anomalies in three children (2007) (79)
- Successful targeting of the NRG1 pathway indicates novel treatment strategy for metastatic cancer (2017) (78)
- Glioma-derived IL-33 orchestrates an inflammatory brain tumor microenvironment that accelerates glioma progression (2020) (78)
- Identification of genes targeted by the androgen and PKA signaling pathways in prostate cancer cells (2006) (78)
- New genomic tools for molecular studies of evolutionary change in threespine sticklebacks (2004) (77)
- A transgenic mouse model demonstrating the oncogenic role of mutations in the polycomb-group gene EZH2 in lymphomagenesis. (2014) (77)
- Epigenetics and human disease. (2009) (77)
- A physical map of the highly heterozygous Populus genome: integration with the genome sequence and genetic map and analysis of haplotype variation. (2007) (76)
- Extensive relationship between antisense transcription and alternative splicing in the human genome. (2011) (75)
- Characterization of the Contradictory Chromatin Signatures at the 3′ Exons of Zinc Finger Genes (2011) (73)
- Functional Characterization of a Catabolic Plasmid from Polychlorinated- Biphenyl-Degrading Rhodococcus sp. Strain RHA1 (2004) (71)
- Recurrent noncoding U1 snRNA mutations drive cryptic splicing in SHH medulloblastoma (2019) (71)
- Osteopoikilosis, short stature and mental retardation as key features of a new microdeletion syndrome on 12q14 (2007) (71)
- Next generation sequencing based approaches to epigenomics. (2010) (71)
- Selective targeting of neuroblastoma tumour-initiating cells by compounds identified in stem cell-based small molecule screens (2010) (70)
- A Hematogenous Route for Medulloblastoma Leptomeningeal Metastases (2018) (70)
- An oligonucleotide fingerprint normalized and expressed sequence tag characterized zebrafish cDNA library. (2001) (69)
- Somatic mutations at EZH 2 Y 641 act dominantly through a mechanism of selectively altered PRC 2 catalytic activity , to increase H 3 K 27 trimethylation (2011) (69)
- A systematic screen for genes expressed in definitive endoderm by Serial Analysis of Gene Expression (SAGE) (2007) (68)
- Integrated genome and transcriptome sequencing identifies a novel form of hybrid and aggressive prostate cancer (2012) (68)
- BreakFusion: targeted assembly-based identification of gene fusions in whole transcriptome paired-end sequencing data (2012) (66)
- TBL1XR1/TP63: a novel recurrent gene fusion in B-cell non-Hodgkin lymphoma. (2012) (66)
- Pan-cancer analysis of advanced patient tumors reveals interactions between therapy and genomic landscapes (2020) (65)
- Significance of TP53 Mutation in Wilms Tumors with Diffuse Anaplasia: A Report from the Children's Oncology Group (2016) (65)
- Cell culture and Drosophila model systems define three classes of anaplastic lymphoma kinase mutations in neuroblastoma (2012) (64)
- Assessment of algorithms for high throughput detection of genomic copy number variation in oligonucleotide microarray data (2007) (62)
- Identification by full-coverage array CGH of human DNA copy number increases relative to chimpanzee and gorilla. (2005) (61)
- Systematic sequencing of cDNA clones using the transposon Tn5. (2002) (60)
- Integrative genomic analysis identifies key pathogenic mechanisms in primary mediastinal large B-cell lymphoma. (2019) (59)
- Sequence biases in large scale gene expression profiling data (2006) (59)
- Mating factor linkage and genome evolution in basidiomycetous pathogens of cereals. (2006) (59)
- High resolution analysis of follicular lymphoma genomes reveals somatic recurrent sites of copy‐neutral loss of heterozygosity and copy number alterations that target single genes (2010) (57)
- Epigenetic and transcriptional determinants of the human breast (2015) (57)
- The genomic and transcriptomic landscape of anaplastic thyroid cancer: implications for therapy (2015) (57)
- Medulloblastoma-associated DDX3 variant selectively alters the translational response to stress (2016) (56)
- Generation of ESTs in Vitis vinifera wine grape (Cabernet Sauvignon) and table grape (Muscat Hamburg) and discovery of new candidate genes with potential roles in berry development. (2007) (56)
- Transcriptome analysis for Caenorhabditis elegans based on novel expressed sequence tags (2008) (56)
- Loss of the Notch effector RBPJ promotes tumorigenesis (2014) (56)
- A somatic reference standard for cancer genome sequencing (2016) (55)
- High-throughput plasmid DNA purification for 3 cents per sample. (1999) (55)
- Recurrent genomic rearrangements in primary testicular lymphoma (2015) (55)
- Complete genomic landscape of a recurring sporadic parathyroid carcinoma (2013) (54)
- Generation of a wheat leaf rust, Puccinia triticina, EST database from stage-specific cDNA libraries. (2007) (54)
- Identification of novel lung genes in bronchial epithelium by serial analysis of gene expression. (2006) (54)
- MKNK1 is a YB-1 target gene responsible for imparting trastuzumab resistance and can be blocked by RSK inhibition (2012) (54)
- MLLT1 YEATS domain mutations in clinically distinctive Favourable Histology Wilms tumours (2015) (53)
- Identification and Analyses of Extra-Cranial and Cranial Rhabdoid Tumor Molecular Subgroups Reveal Tumors with Cytotoxic T Cell Infiltration (2019) (53)
- Hypomorphic temperature-sensitive alleles of NSDHL cause CK syndrome. (2010) (53)
- Poly‐gene fusion transcripts and chromothripsis in prostate cancer (2012) (53)
- miR-509-3p is clinically significant and strongly attenuates cellular migration and multi-cellular spheroids in ovarian cancer (2016) (52)
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- Author Correction: Pan-cancer analysis of whole genomes (2023) (1)
- Comprehensive Profiling of Micrornas in Murine Hematopoietic Stem Cells and Lineages Using a Microfluidics Approach (2008) (1)
- 1615PPRACTICAL GUIDELINES FOR ETHICAL AND POLICY ISSUES THAT ARISE FROM THE CLINICAL APPLICATION OF WHOLE GENOME SEQUENCING IN CANCER PATIENTS. (2014) (1)
- O-203 Construction of a DNA microarray with complete coverage of the human genome (2003) (1)
- Malignant Reprogramming of Progenitors into Leukemia Stem Cells Is Enhanced By Upregulation of CD44 Transcript Variant 3 in Malignant Microenvironments (2014) (1)
- Rearrangements in Nucleoporin Family of Genes in Childhood Acute Myeloid Leukemia: A Report from Children Oncology Group and NCI/COG Target AML Initiative (2015) (1)
- Integrative multi‐omic analysis reveals neurodevelopmental gene dysregulation in CIC ‐knockout and IDH1 ‐mutant cells (2021) (1)
- Clinical outcomes after whole genome sequencing in patients with metastatic non-small cell lung cancer. (2017) (1)
- Title : Estimating Absolute Methylation Levels at Single CpG Resolution from Methylation Enrichment and Restriction Enzyme Sequencing Methods Running title : methylCRF predicts single CpG resolution methylome (2013) (1)
- Pyruvate kinase inhibits proliferation during postnatal cerebellar neurogenesis and suppresses 2 medulloblastoma formation 3 4 Running Title 5 PKM suppresses medulloblastoma 6 7 (2017) (1)
- Frequent Genetic Alterations of PI3K-AKT Pathway and Their Clinical Significance in Germinal Center B-Cell-like Diffuse Large B-Cell Lymphoma (2016) (1)
- Burkitt Lymphoma Genome Sequencing Project (BLGSP): Introduction (2016) (1)
- Availability of tumour gene expression data facilitates clinical decision-making for patients with advanced cancers (2016) (1)
- ATRT-09. WHOLE GENOME AND EPIGENOME CHARACTERIZATION LINKS ATRT-MYC TO A SUBGROUP OF RENAL RHABDOID TUMORS (2018) (1)
- Comparative Transcriptome Analysis of Different Subsets of CD34+ Normal and Chronic Myeloid Leukemia Cells Identifies Novel Perturbations in the CML Stem Cell Population. (2007) (1)
- OMICS AND PROGNSTIC MARKERS (2013) (1)
- Whole transcriptome sequencing in metastatic cancer: A review of expression outliers in 113 metastatic breast cancer patients. (2019) (1)
- Serial analysis of gene expression profiles of developmental stages in non-small cell lung carcinoma. (2004) (1)
- PTPS-08HEMATOGENOUS DISSEMINATION OF MEDULLOBLASTOMA METASTASES TO THE LEPTOMENINGES (2015) (1)
- GRETA: an R package for mapping in silico genetic interaction and essentiality networks (2022) (1)
- Marked Differences in the Genomic Landscape of Pediatric Compared to Adult Acute Myeloid Leukemia: A Report from the Children's Oncology Group and NCI/COG Therapeutically Applicable Research to Generate Effective Treatments (TARGET) Initiative (2016) (1)
- FAS Mutations Accelerate Lymphoma Growth and Induce Therapeutic Resistance (2014) (1)
- A BAC physical map of the bovine genome (2004) (1)
- Comprehensive transcriptome analysis reveals link between epigenetic dysregulation, endogenous retrovirus expression and immunogenicity in metastatic colorectal carcinoma. (2019) (1)
- Variants in DNA repair genes and their association with late side-effects in prostate brachytherapy patients (2008) (1)
- Comprehensive genomic analysis of metastatic pancreatic ductal adenocarcinoma (mPDAC) reveals a significant proportion of clinical actionable aberrations. (2019) (1)
- Whole-genome DNA and RNA sequencing in patients with metastatic colorectal cancer (mCRC). (2014) (1)
- Integrated genomics elucidates relative spatial homogeneity of embryonal brain tumors (2015) (1)
- Applications of High-Throughput Sequencing (2012) (1)
- number increases relative to chimpanzee and gorilla Identification by full-coverage array CGH of human DNA copy (2008) (1)
- Protein Tyrosine Phosphatase Type-1 (PTPN1) Is Frequently Mutated In Primary Mediastinal B Cell Lymphoma and Hodgkin Lymphoma (2013) (1)
- INTEGRATIVE GENOMIC ANALYSIS IDENTIFIES KEY PATHOGENIC CONCEPTS IN PRIMARY MEDIASTINAL LARGE B‐CELL LYMPHOMA (2019) (1)
- Identification of Genes Frequently Mutated In FL and DLBCL with Transcriptome, Genome and Exome Sequencing (2010) (1)
- GENT-11. SMALL MOLECULE EPIGENETIC SCREEN IDENTIFIES NOVEL EZH2 AND HDAC INHIBITORS THAT TARGET GLIOBLASTOMA BRAIN TUMOR-INITIATING CELLS (2016) (1)
- Abstract 247: ADAR1 promotes malignant progenitor reprogramming in chronic myeloid leukemia. (2013) (1)
- Integration of Whole-Genome Sequencing With Circulating Tumor DNA Analysis Captures Clonal Evolution and Tumor Heterogeneity in Non-V600 BRAF Mutant Colorectal Cancer. (2020) (1)
- Transcriptome-wide mutation discovery in patients in a phase II clinical trial of first-line erlotinib for clinically selected patients with advanced non-small cell lung cancer. (2009) (1)
- Molecular etiology of an indolent lymphoproliferative disorder determined by whole-genome sequencing (2016) (1)
- P-129 Gene expression profiles of developmental stages of non-small cell lung carcinoma (2003) (1)
- Abstract 926: Whole genome and transcriptome sequencing defines the spectrum of somatic changes in high-risk neuroblastoma (2011) (1)
- Burkitt Lymphoma Genome Sequencing Project (BLGSP): Integrative Genomic and Transcriptomic Characterization of Burkitt Lymphoma (2017) (1)
- The use of whole-genome sequencing in therapeutic for decision making in patients with advanced malignancies. (2014) (1)
- The Double-Hit Gene Expression Signature Defines a Clinically and Biologically Distinct Subgroup within GCB-DLBCL (2018) (1)
- Single-cell landscapes of primary glioblastomas and matched organoids and cell lines reveal variable retention of inter- and intra-tumor heterogeneity (2021) (1)
- Whole genome sequencing in metastatic breast cancer: Lessons learned from the BC Cancer personalized oncogenomics program. (2018) (1)
- 787 The Cancer Genome Atlas (TCGA) project analysis of micro-RNA and gene expression subtypes of high-grade, muscle-invasive urothelial carcinoma (2016) (1)
- KEY GENETIC AND MOLECULAR ABERRATIONS IDENTIFIED IN BOTH ADULT AND EBV‐POSITIVE BURKITT LYMPHOMA PATIENTS (2021) (1)
- ASXL1 and ASXL2 Mutations in Childhood AML Are Strongly Associated with t(8;21) but Do Not Independently Impact on Prognosis: A Report from the Children's Oncology Group and NCI/COG Target Initiative (2015) (1)
- Sabutoclax, a Novel Pan BCL2 Family Inhibitor, Sensitizes Dormant Blast Crisis Chronic Myeloid Leukemia Stem Cells to Dasatinib (2012) (1)
- Implementation of Watson Genomic Analytics processing to improve the efficiency of interpreting whole genome sequencing data on patients with advanced cancers. (2015) (1)
- Single Cell Transcriptome Analysis Reveals Changing Levels and Distributions of Stemness across Disease States in Pediatric AML (2017) (1)
- Resuspension of DNA Sequencing Reaction Products in Agarose Increases Sequence Quality on an Automated Sequencer (2002) (1)
- Construction and optimization of chromosome arm-specific comparative genomic hybridization arrays for identifying genetic alterations in preinvasive lung cancers. (2004) (1)
- BCL2 Is Highly Mutated In Diffuse Large B-Cell Lymphoma (2010) (1)
- Title: A patient with vertebral, cognitive and behavioural abnormalities and a de novo deletion of NRXN1 Authors: (2007) (1)
- Integrative Analysis of Single-Cell RNA-Seq and ATAC-Seq Data across Treatment Time Points in Pediatric AML (2020) (1)
- TNFRSF14 Is Mutated in a Subset of Follicular Lymphoma and Correlated with Inferior Prognosis. (2009) (1)
- The genomic and transcriptomic landscape of anaplastic thyroid cancer: implications for therapy (2015) (0)
- Recurrent MEF2D Fusions Define A New Subtype of Acute Lymphoblastic Leukemia Associated with Older Age at Diagnosis and Poor Outcome (2016) (0)
- Tracking Normal and Chronic Myeloid Leukemia Progenitor Cell Cycle Kinetics in a Defined Niche Using Live Time Lapse Confocal Imaging with Fucci2BL a Novel Lentiviral Bicistronic Reporter (2015) (0)
- Comprehensive whole genome sequence analyses yields novel genetic and structural insights for Intellectual Disability (2017) (0)
- Abstract B57: Early-onset pancreatic ductal adenocarcinomas are characterized by a distinct mutational landscape (2019) (0)
- SPATA: An Accurate GUI Tool forDe NovoTranscriptome Assembly (2010) (0)
- TABLE S1 C. gattii genome statistics. (2011) (0)
- DNA Methylation-Based Burkitt Lymphoma Epitypes Have Distinct Molecular and Clinical Features (2022) (0)
- Relapse Timing Is Associated with Distinct Evolutionary Dynamics and Response to Salvage Therapy in DLBCL (2022) (0)
- Author Correction: Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples (2020) (0)
- Epigenetic landscape in IDH1 mutant glioma (2017) (0)
- Improved structural variant interpretation for hereditary cancer susceptibility using long-read sequencing (2020) (0)
- A case of the utilization of genomic information in the management of metastatic colorectal cancer. (2013) (0)
- Abstract 5226: Genomic analysis of pancreatic ductal adenocarcinoma in a patient with MUTYH-associated polyposis (2016) (0)
- GLI2 inhibition abrogates human leukemia stem cell dormancy (2015) (0)
- Genetic Subdivisions of Follicular Lymphoma Defined by Distinct Coding and non-coding Mutation Patterns. (2023) (0)
- New Candidate Regulators of Hematopoietic Stem Cells Identified from Transcriptional Comparisons of Highly Purified Populations of Longterm Repopulating Cells with Markedly Different in Vivo Self-Renewal Activities (2008) (0)
- RETRACTED ARTICLE: Tumor necrosis factor overcomes immune evasion in p53-mutant medulloblastoma (2020) (0)
- Clinical benefit of whole genome and transcriptome analysis (WGTA) in metastatic colorectal cancer (MCRC): Results from the personalized oncogenomics program (POG). (2018) (0)
- Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution (2020) (0)
- Subclonal architecture, evolutionary trajectories and patterns of inheritance of germline variants in pediatric glioblastoma (2018) (0)
- Abstract 4283: Whole genome sequencing is superior to cancer panels to aid in decision-making in patients with advanced malignancies (2014) (0)
- Abstract LB-180: The genetic landscape of Wilms tumor (2016) (0)
- The Drivers, Mechanisms, and Consequences of Genome Instability in HPV-Driven Cancers (2022) (0)
- Next generation sequencing of oligodendroglioma – a work in progress (2011) (0)
- Combined serial analysis of gene expression and transcription factor binding site prediction identifies novel-candidate-target genes of Nr2e1 in neocortex development (2015) (0)
- LYMPHOID NEOPLASIA An RCOR1 loss – associated gene expression signature identi fi es a prognostically signi fi cant DLBCL subgroup (2015) (0)
- Predictive markers of checkpoint inhibitor activity in adult metastatic solid tumours (2019) (0)
- Ploidetect enables pan-cancer analysis of the causes and impacts of chromosomal instability (2021) (0)
- Immune Activation following Irbesartan Treatment in a Colorectal Cancer Patient: A Case Study (2023) (0)
- Abstract LB-202: The rare, highly malignant small cell carcinoma of the ovary displays common inactivating germline and somatic mutations in the tumor suppressor SMARCA4 (2014) (0)
- Abstract A190: Management of germline findings revealed throughout the course of tumor-normal whole genome sequencing in oncology (2018) (0)
- Abstract A184: Clinical application of whole genome and transcriptome sequencing in cancer care (2018) (0)
- Abstract 3087: Whole genome sequencing of rhabdoid tumors of the kidney (2014) (0)
- Clinical Cancer esearch an Cancer Biology tem-Level Analysis of Neuroblastoma Tumor – Initiating ls Implicates AURKB as a Novel Drug Target R Neuroblastoma (2010) (0)
- Abstract IA11: Overcoming immune evasion in pediatric brain tumors (2020) (0)
- Towards a Unified Genetic Classification System for Diffuse Large B-Cell Lymphoma (DLBCL) (2022) (0)
- P-127 Transcriptome profiling technologies at the British Columbia Cancer Agency (2003) (0)
- M1982 Identification of Differentially Expressed Alternative mRNA Isoforms Associated with Chemotherapy Resistance in Colon Cancer Cell Lines (2008) (0)
- Author Correction: Patterns of somatic structural variation in human cancer genomes (2020) (0)
- TET2 Mutations Are Highly Associated with RUNX1-RUNX1T1 Translocations and NPMc+ in Childhood AML: a Report from Children's Oncology Group AAML03P1, AAML0531 and NCI/COG Target AML Initiative (2015) (0)
- Genetic Alterations of Gα13 Signaling Pathway with BCL2 over-Expression Confers Lymphoma Dissemination and Inferior Outcome in Germinal Center B Cell Diffuse Large B Cell Lymphoma (2015) (0)
- Award Number: W81XWH-07-1-0503 TITLE: Identification of Novel Genes and Candidate Targets in CML Stem Cells PRINCIPAL INVESTIGATOR: Dr. Connie Eaves CONTRACTING ORGANIZATION: British Columbia Cancer Agency (2009) (0)
- PS2 - 167 CIC Deficiency is Associated with Dysregulation of Genes Involved in Cell Adhesion and Developmental Processes (2016) (0)
- 232 Management of germline findings revealed throughout the course of tumor-normal whole genome sequencing in oncology (2015) (0)
- Beyond BRCA? clinical utility of homologous recombination deficiency in gastrointestinal cancers. (2021) (0)
- The Copy Number Landscape of Relapsed and Refractory Diffuse Large B-Cell Lymphoma (2020) (0)
- The RNA Editase ADAR1 Promotes Malignant Progenitor Reprogramming in Chronic Myeloid Leukemia. (2012) (0)
- Divergent Modes of Tumor Evolution Underlie Histological Transformation and Early Progression of Follicular Lymphoma (2016) (0)
- iron overload: identification of a novel TfR2 mutation Transferrin receptor 2 (TfR2) and HFEmutational analysis in non-C282Y (2013) (0)
- COPY NUMBER VARIATION ANALYSIS IDENTIFIES DISTINCT GENOMIC FEATURES IN ADULT BURKITT LYMPHOMA (2021) (0)
- P-302 Fine mapping of breakpoints of genetic alterations on chromosome 3p in lung cancer by array CGH (2003) (0)
- fRFLP and fAFLP: Medium-Throughput Genotyping by Fluores- cently Post-Labeling Restriction Digestion (2002) (0)
- Genomic research in British Columbia [audiorecording] (2003) (0)
- Characterization of Genomic Rearrangements Involving CIITA and SOCS1 Using Targeted Capture Sequencing of Archival Tissue Specimens (2016) (0)
- Cost-Effectiveness of Molecularly Guided Treatment in Diffuse Large B-Cell Lymphoma (DLBCL) in Patients under 60 (2022) (0)
- Massive Parallel Sequencing of Small RNAs from Newborn Mouse Ovaries Identifies Novel miRNAs Preferentially Expressed in the Ovaries. (2009) (0)
- Sequencing and analysis of 10967 full-length cDNA clones from Xenopus laevis and Xenopus tropicalis (2005) (0)
- Multi-omic analysis of CIC’s functional networks reveals novel interaction partners and a potential role in mitotic fidelity (2023) (0)
- 1570ODEMONSTRATION OF TEMPORAL HETEROGENEITY IDENTIFIED BY GENOME SEQUENCING AND THE POTENTIAL EFFECT ON TREATMENT DECISIONS FOR ADVANCED CANCER PATIENTS. (2014) (0)
- Novel Genetic Subgroups Inform on Shared Pathobiology within Adult and Pediatric Burkitt Lymphoma (2021) (0)
- Integrated genomic characterization of oesophageal carcinoma (2017) (0)
- Epigenetic landscape in IDH 1 mutant glioma (2017) (0)
- Abstract 4346: Integrated whole genome profiling of the immune tumour interaction identifies predictive biomarkers of checkpoint inhibitor response in metastatic cancer (2018) (0)
- TNF superfamily cytokines overcome immune evasion in medulloblastoma (2019) (0)
- WHOLE GENOME SEQUENCING OF MATCHED PRIMARY AND RELAPSED DLBCL REVEALS DISTINCT EVOLUTIONARY DYNAMICS ASSOCIATED WITH RELAPSE TIMING (2021) (0)
- Transcriptomics in the Age of Ultra High-Throughput Sequencing (2013) (0)
- CIC (capicua transcriptional repressor) (2017) (0)
- Abstract 2473: Breast cancer whole genomes link homologous recombination deficiency (HRD) with therapeutic outcomes (2017) (0)
- Abstract 959: FAS mutations induce therapeutic resistance in non-Hodgkin lymphomas (2014) (0)
- Abstract 98: Personalized therapy choice integrating genome and expression data in advanced cancers (2021) (0)
- Caenorhabditis Identification and analysis of internal promoters in (2007) (0)
- Abstract AS18: The somatic mutational landscape of endometriosis associated ovarian cancers and precursor lesions (2015) (0)
- tem-Level Analysis of Neuroblastoma Tumor–Initiating ls Implicates AURKB as a Novel Drug Target (2010) (0)
- Abstract 3480:TMEM30Aloss-of-function mutations drive lymphomagenesis and confer therapeutically exploitable vulnerability in B-cell lymphoma (2019) (0)
- Gene Expression Analysis in Pharmacogenetics and Pharmacogenomics (2005) (0)
- Combinatorial and Machine Learning Approaches for Improved Somatic Variant Calling From Formalin-Fixed Paraffin-Embedded Genome Sequence Data (2022) (0)
- Characteristics cDNA Microarray : Data Mining and Interspecific Hybridization Development and Application of a Salmonid EST Database and (2004) (0)
- COMBINED DRUG SCREENING AND PHOSPHOPROTEOMICS IDENTIFIES CANDIDATE BRAIN TUMOR THERAPEUTICS AND NOVEL TARGETS IN PRIMARY HUMAN BRAIN TUMOR-INITIATING CELLS (2014) (0)
- Patient selection for a developmental therapeutics program using whole genome and Transcriptome analysis (2020) (0)
- Integrative analysis of genome-wide loss of heterozygosity and mono-allelic expression at nucleotide resolution reveals disrupted pathways in triple negative breast cancer Supplemental Material (2012) (0)
- Abstract 375: A novel diagnostic assay for detection of primate-specific RNA editing events in leukemia stem cells (2014) (0)
- Author Correction: The evolutionary history of 2,658 cancers (2023) (0)
- AUTOMATED IMAGE ANALYSIS FOR DNA FINGERPRINTING (2002) (0)
- 2011 Jeremy Jass Prize for Research Excellence in Pathology (2012) (0)
- Evolution of genomic instability in metastatic cancer. (2018) (0)
- Author Correction: Failure of human rhombic lip differentiation underlies medulloblastoma formation (2022) (0)
- MB-08FUNCTIONAL ROLES OF CCL2 IN MEDULLOBLASTOMA LEPTOMENINGEAL METASTASIS (2016) (0)
- Outcomes of whole genome and transcriptome sequencing (WGTS) in advanced gynecologic malignancies: Results from the personalized oncogenomics program (POG) (2019) (0)
- 1450-1545 Young Investigator Awards & Presentations Basic/Translational Exploring cellular subpopulations in glioblastoma and matched organoids using single-cell RNA-seq 52 (2018) (0)
- Abstract 5340: Bioinformatic analyses approaches for personalized oncogenomics (2014) (0)
- Year Excellence in Education Excellence in Basic Science Research Excellence in Clinical or Applied Research Service to the University & Community Overall Excellence Outstanding Contributions by a Senior Faculty Member Overall Excellence - Early Career Overall Excellence - Senior Faculty (2015) (0)
- Corrigendum: Genomic profiling of pelvic genital type leiomyosarcoma in a woman with a germline CHEK2:c.1100delC mutation and a concomitant diagnosis of metastatic invasive ductal breast carcinoma (2018) (0)
- Practice patterns of medical oncologists: a survey of advance care planning in the outpatient setting (2020) (0)
- Sequence analysis De novo transcriptome assembly with ABySS (2009) (0)
- Towards the Human Cancer Genome Project: A Sequence-Ready Physical Map of a Follicular Lymphoma Genome. (2005) (0)
- A microRNA Expression-Based Model Predicts Event Free Survival in Pediatric Acute Myeloid Leukemia (2016) (0)
- Author Correction: Inferring structural variant cancer cell fraction (2022) (0)
- DISCOVERY OF RECURRENT ONCOGENIC MUTATIONS IN LYMPHOMA BY RNA-SEQ (2011) (0)
- Integrative analysis of KRAS-wildtype pancreatic ductal adenocarcinoma reveals unique similarities to extrahepatic cholangiocarcinoma. (2022) (0)
- Abstract 12: Metastatic neuroblastoma cancer stem cells display a mixed phenotype of tumor and niche origin required for survival (2010) (0)
- P-303 Construction of a high resolution CGH array for chromosome 5p and analysis of SCLC and NSCLC cell lines (2003) (0)
- Differences in the Transcriptomes of Highly Purified Fetal Liver and Adult Bone Marrow Hematopoietic Stem Cells Revealed by Long Serial Analysis of Gene Expression (LongSAGE) (2007) (0)
- Previously documented mutations in the epidermal growth factor receptor (EGFR) gene in a non-small cell lung cancer (NSCLC) population treated with gefitinib are not associated with response. (2006) (0)
- populations from tumor whole-genome sequence data TITAN : inference of copy number architectures in clonal cell Material Supplemental (2014) (0)
- A 02 IDENTIFICATION OF A NEW CAUSATIVE GENE FOR ATAXIA WITH OCULAR MOTOR APRAXIA (2012) (0)
- Capicua regulates neural stem cell proliferation and lineage specification through control of Ets factors (2019) (0)
- Large-Scale High Resolution Integration of Copy Number and Gene Expression in DLBCL Reveals Focal and Frequent Deletions in Chromatin Modifying Genes with Outcome Correlation (2012) (0)
- Author Correction: Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution (2020) (0)
- 567 Genomic Analysis of Non-Hodgkin Lymphomas Reveals Mutations in Chromatin Remodelling Genes (2012) (0)
- Subject Index Vol. 102, 2003 (2004) (0)
- Abstract PR02: Integrated genomic analysis of a recurrent ghost cell odontogenic carcinoma (2016) (0)
- Practical application of whole genome and transcriptome tumour analysis to guide chemotherapy decision-making for patients with advanced cancers. (2013) (0)
- Molecular Correlates of Central Nervous System Relapse in Diffuse Large B-Cell Lymphoma (2019) (0)
- Abstract A24: Gene expression along the glycolysis-cholesterol synthesis axis and outcome in pancreatic cancer (2019) (0)
- Genetic Alterations In Immune Cell Crosstalk Genes In Diffuse Large B-Cell Lymphoma Predict Survival (2013) (0)
- GE-21DRASTIC GENOMIC DIVERGENCE OF RECURRENT MEDULLOBLASTOMA INVALIDATES TARGETED THERAPIES DISCOVERED AT DIAGNOSIS. (2014) (0)
- Genome-wide discovery of somatic regulatory variants in diffuse large B-cell lymphoma (2018) (0)
- The genetic basis and cell of origin of mixed phenotype acute leukaemia (2018) (0)
- Contents Vol. 102, 2003 (2004) (0)
- Abstract 1647: CAPTIV-8: A prospective trial of atezolizumab using a multivariate model incorporating whole genome and transcriptome analysis (2021) (0)
- P-300 Identification of regions of DNA alteration on chromosome arm 1p in NSCLC and SCLC (2003) (0)
- Abstract B053: Targeting SMURF1 with low-dose proteasome inhibitors in pancreatic cancer organoids (2022) (0)
- Inhibition Of Inflammation Driven Leukemia Stem Cell Self-Renewal With a Selective JAK2 Antagonist (2013) (0)
- Comprehensive Genomic and Transcript Profiling of CBL Gene in Childhood AML: A Report from Children's Oncology Group Studies AAML03P1, AAML0531 and COG/NCI Target AML Initiative (2015) (0)
- FAS Mutations Are Associated with Therapeutic Resistance in Follicular Lymphoma (2012) (0)
- Accurate Detection of the microRNA Transcriptome in a Leukemia Progression Model. (2007) (0)
- P3-108: Correlative genomics in a phase II clinical trial of first-line therapy of erlotinib for clinically selected patients with advanced non-small cell lung cancer (2007) (0)
- Abstract 4340: Integrating whole genome and transcriptome analysis to inform treatment decisions in the metastatic cancer clinical setting (2018) (0)
- Abstract 2914: Phosphoproteomic and transcriptional biomarkers predict response to SAR302503, a JAK2 inhibitor, in human acute myeloid leukemia preclinical models (2014) (0)
- 29 Unraveling molecular drivers of brain cancers at the clinical setting (2018) (0)
- Massively Parallel MicroRNA Profiling in the Haematologic Malignancies (2019) (0)
- Recurrent DNA Mutations In Non-Hodgkin Lymphomas Reveal Candidate Therapeutic Targets (2010) (0)
- Abstract 3804: Rare DNA variants are enriched at the BARD1 locus and likely influence neuroblastoma susceptibility. (2013) (0)
- Abstract IA42: Detecting and quantifying mutations associated with treatment resistance in aggressive lymphomas using ctDNA (2020) (0)
- Coronavirus The Genome Sequence of the SARS-Associated (2010) (0)
- CSIG-12. EXPLORING THE FUNCTIONAL RELATIONSHIP BETWEEN CAPICUA (CIC) AND ATAXIN-1-LIKE (ATXN1L) IN GLIOMA (2017) (0)
- Base-Pair Resolution of Somatic and Germline-Derived Genome Rearrangement Breakpoints in Follicular Lymphoma. (2009) (0)
- Personalized oncogenomics (2010) (0)
- TEXT S1 Materials and Methods text and supplemental figures. Download (2011) (0)
- in mantle cell lymphoma mutations NOTCH1 Whole transcriptome sequencing reveals recurrent (2012) (0)
- Abstract B81: Gene expression analysis demonstrates prognostic subtypes in metastatic pancreatic ductal adenocarcinoma (PDAC) (2016) (0)
- Comparative Whole Transcriptome Shotgun Sequencing (WTSS) of Myeloma at Diagnosis and at Drug-Resistant Relapse. (2009) (0)
- A 1 Investigations of the functional interactions between CIC and ATXN 1 L in Oligodendroglioma (2017) (0)
- DEV125252 4340..4350 (2015) (0)
- Lymphoma biology 373 B-CELL LYMPHOMA CELLS OVEREXPRESSING BMI-1 ARE CORRELATED WITH DRUG RESISTANCE THROUGH ENHANCED EXPRESSION OF SURVIVIN AND ARE MORE EFFECTIVELY ELIMINATED BY T CELLS WITH CHIMERIC RECEPTOR AGAINST CD 38 THAN CD 19 (2011) (0)
- Defining a role for PARP inhibition in the treatment of GBM ” (2015) (0)
- Modern Epigenomics DNA Methylomics (2012) (0)
- Whole genome and transcriptome sequencing of lung cancer: Options for personalized cancer treatment. (2017) (0)
- Abstract 2445: Integrative genetic analysis identifies therapeutic relevance of cell of origin-specific genetic alterations in diffuse large B-cell lymphoma (2017) (0)
- Management of germline findings revealed throughout the course of tumor-normal whole genome sequencing in oncology. (2017) (0)
- P-116 Using the permutation test to analyze lung cancer SAGE libraries (2003) (0)
- Constrained FL: A Genetically Distinct Subgroup of Follicular Lymphoma with Low Rates of Somatic Hypermutation and a Reduced Propensity for Histologic Transformation (2021) (0)
- and discovery in human embryonic stem cells Application of massively parallel sequencing to microRNA profiling Material Supplemental (2008) (0)
- Genetic Characterization and Clinical Impact of Loss of MHC Class I and II Expression in De Novo Diffuse Large B-Cell Lymphoma (2017) (0)
- ATRT-09. INTEGRATIVE ANALYSES OF GENE REGULATORY LANDSCAPES REVEAL RHABDOID TUMOR SUBGROUPS WITH POSSIBLE IMMUNE MODULATION THROUGH EPIGENETIC DYSREGULATION (2019) (0)
- 27 Characterization of the molecular consequences of CIC-knockout and neomorphic IDH1 R132H mutation on transcriptomic and epigenomic landscapes (2018) (0)
- O-184 Asian ethnicity, somatic epidermal growth factor receptor (EGFR) mutations and response to gefitinib in non-small cell lung cancer patients treated in a North American setting (2005) (0)
- Functional Investigation of the Gene NFKBIZ and the Impact of 3'UTR Mutations in Diffuse Large B-Cell Lymphoma (2017) (0)
- Targeted Sequencing Reveals Novel Gene Mutations Associated with Transformation and Early Progression in Follicular Lymphoma (2016) (0)
- The whole genome landscape of adult metastatic sarcoma. (2019) (0)
- Transcriptome Analysis of Pediatric AML Reveals Non Protein-Coding RNAs Associated with Poor Survival Outcome and Treatment Resistance (2019) (0)
- Automated Library Construction and Analysis for High-Throughput Nanopore Sequencing of SARS-CoV-2 (2022) (0)
- Differential Expression of Mirna Species in Cancer and the Contribution of MiR-223 to the Development of Acute Myeloid Leukemia. (2009) (0)
- Alteration of Chromatin Modifiers and Misregulation of Transcription Factors Define the Genomic Profile of Infant AML (2016) (0)
- Homologous recombination deficiency signatures in gastrointestinal and thoracic cancers correlate with platinum therapy duration (2023) (0)
- Genome-wide analysis of Nkx2.2 binding sites using ChIP-tag sequencing (ChIP-TS) (2007) (0)
- Publisher Correction: The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions (2019) (0)
- Differential Hive Plots: Seeing Networks Change (2017) (0)
- Retraction Note: Tumor necrosis factor overcomes immune evasion in p53-mutant medulloblastoma (2021) (0)
- Cancer esearch cular and Cellular Pathobiology uired TNFRSF 14 Mutations in Follicular Lymphoma Are R ociated with Worse Prognosis (2010) (0)
- Precision Care of Brain Tumour Patients via Personalized OncoGenomics – Promises and Challenges (2015) (0)
- ATPS-28COMBINED DRUG SCREENING AND PHOSPHOPROTEOMICS IDENTIFIES CANDIDATE BRAIN TUMOR THERAPEUTICS IN PRIMARY HUMAN BRAIN TUMOR-INITIATING CELLS (2015) (0)
- P-125 Deriving the transformation events in tumorogenesis using data from serial analysis of gene expression (2003) (0)
- MB-21INTEGRATED GENOMICS ELUCIDATES RELATIVE SPATIAL HOMOGENEITY OF EMBRYONAL BRAIN TUMORS. (2015) (0)
- Mayer-Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana-1999 (2016) (0)
- Comprehensive miRNA sequence analysis reveals survival differences in diffuse large B-cell lymphoma patients (2015) (0)
- Abstract PR-009: Proteotranscriptomic classification and characterization of pancreatic neuroendocrine neoplasms (2020) (0)
- Profiling thyroid cancers on the molecular level (2012) (0)
- Genome-Wide Methylation and Haplotype-Resolved Aberrant Somatic Hypermutation Patterns in B-Cell Lymphomas (2022) (0)
- Life-cycle health technology assessment for precision oncology. (2022) (0)
- NTRK2 Fusion Driven Pediatric Glioblastoma: Identification of key molecular drivers by personalized oncology (2019) (0)
- Mutations Affecting RNA Binding Proteins Are a Novel Feature of Mantle Cell Lymphoma (2019) (0)
- TRIM25 promotes Capicua degradation independently of ERK in the absence of ATXN1L (2020) (0)
- Megabase-scale methylation phasing using nanopore long reads and NanoMethPhase (2021) (0)
- Abstract A10: MLL2 interactions in follicular and diffuse large B-cell lymphoma (2013) (0)
- Comprehensive genomic analysis in metastatic pancreatic ductal adenocarcinoma (PDAC). (2016) (0)
- Abstract LB-312: The somatic mutational landscape of ovarian clear cell carcinoma and its precursor lesions (2014) (0)
- Genome-wide discovery of somatic coding and regulatory variants in Diffuse Large B-cell Lymphoma (2017) (0)
- Combined JAK/STAT5A and BCR-ABL Inhibition Impairs Blast Crisis Chronic Myeloid Leukemia Stem Cell Self-Renewal (2012) (0)
- MB-100DIVERGENT CLONAL SELECTION DOMINATES MEDULLOBLASTOMA AT RECURRENCE (2016) (0)
- Abstract 2631: Restrictions on access to systemic therapy limit the application of whole genome sequencing in clinical care (2016) (0)
- Abstract 1730:DACH1gene deletion extends portraits of human prostate cancer (2019) (0)
- PD2-2-7: Two wrongs make a right: the use of whole genome amplification for pair-wise genome-wide copy number analysis of limited patient material (2007) (0)
- Corrigendum: Small cell carcinoma of the ovary, hypercalcemic type, displays frequent inactivating germline and somatic mutations in SMARCA4 (2014) (0)
- Increasing quality, throughput and speed of sample preparation for strand-specific messenger RNA sequencing (2017) (0)
- Abstract 1122: Personalized oncogenomics in advanced stage breast cancer (2015) (0)
- Abstract LB-173: Genome analysis informs chemotherapy decision-making in patients with advanced malignancies. (2013) (0)
- Retraction Note: Tumor necrosis factor overcomes immune evasion in p53-mutant medulloblastoma (2021) (0)
- TMBur: a distributable tumor mutation burden approach for whole genome sequencing (2022) (0)
- Recurrent Copy Number Alterations Contribute to a Unique Genetic Landscape in Relapsed-Refractory DLBCL (2022) (0)
- Complex Structural Variation Associated with Enhancer Hijacking and Loss of Tumor Suppressors in Mantle Cell Lymphoma (2021) (0)
- GE-28INTEGRATED GENOMICS DEMONSTRATE RELATIVE SPATIAL HOMOGENEITY IN PEDIATRIC BRAIN TUMORS. (2014) (0)
- Relapse timing is associated with distinct evolutionary dynamics in DLBCL (2023) (0)
- LYMPHOID NEOPLASIA Comprehensive characterization of programmed death ligand structural rearrangements in B-cell non-Hodgkin lymphomas (2016) (0)
- Erratum: Sequencing and analysis of 10,967 full-length cDNA clones from Xenopus laevis and Xenopus tropicalis reveals post-tetraploidization transcriptome remodeling (Genome Research (2006) 16, (796-803)) (2006) (0)
- FUNCTIONAL CHARACTERIZATION OF NFKBIZ 3′ UTR MUTATIONS IN DIFFUSE LARGE B‐CELL LYMPHOMA (2019) (0)
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