Margaret Gardel

Q: What Schools Are Affiliated With Margaret Gardel

Margaret Gardel is affiliated with the following schools: Harvard University, Brown University, Vrije Universiteit Amsterdam, University of California, Santa Barbara, Massachusetts Institute of Technology, University of Chicago

Margaret Gardel's AcademicInfluence.com Rankings

Margaret Gardel

Physics

#5994

World Rank

#7895

Historical Rank

#1694

USA Rank

Biophysics

#313

World Rank

#325

Historical Rank

#54

USA Rank

physics Degrees

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Physics

Margaret Gardel's Degrees

PhD Physics University of California, Santa Barbara
Bachelors Physics University of California, Santa Barbara

Why Is Margaret Gardel Influential?

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According to Wikipedia, Margaret Lise Gardel is an American biophysicist. She is the Horace B. Horton Professor in the Department of Physics at the University of Chicago. Education After Gardel earned her bachelor’s degree in physics and mathematics from Brown University, she was accepted into physics graduate programs at Harvard University. While completing her PhD, she became interested in the ways actin deforms in response to external mechanical stress. She was encouraged by Clare Waterman and various cell biologists to leave her postdoc position and join a research team at Scripps Research Institute.

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Margaret Gardel's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Elastic Behavior of Cross-Linked and Bundled Actin Networks (2004) (1112)
Giant dielectric constant response in a copper-titanate (2000) (977)
Mechanical integration of actin and adhesion dynamics in cell migration. (2010) (841)
High resolution traction force microscopy based on experimental and computational advances. (2008) (514)
Cell-ECM traction force modulates endogenous tension at cell–cell contacts (2011) (454)
Anomalous diffusion probes microstructure dynamics of entangled F-actin networks. (2004) (453)
Forcing cells into shape: the mechanics of actomyosin contractility (2015) (437)
Traction stress in focal adhesions correlates biphasically with actin retrograde flow speed (2008) (426)
Mechanics of the F-actin cytoskeleton. (2010) (423)
Prestressed F-actin networks cross-linked by hinged filamins replicate mechanical properties of cells. (2006) (410)
F-actin buckling coordinates contractility and severing in a biomimetic actomyosin cortex (2012) (331)
Identification and characterization of a small molecule inhibitor of formin-mediated actin assembly. (2009) (327)
Tension is required but not sufficient for focal adhesion maturation without a stress fiber template (2012) (319)
United we stand – integrating the actin cytoskeleton and cell–matrix adhesions in cellular mechanotransduction (2012) (301)
Microrheology of entangled F-actin solutions. (2003) (271)
Colloid surface chemistry critically affects multiple particle tracking measurements of biomaterials. (2004) (234)
PyK2 and FAK connections to p190Rho guanine nucleotide exchange factor regulate RhoA activity, focal adhesion formation, and cell motility (2008) (219)
Regulation of cell motile behavior by crosstalk between cadherin- and integrin-mediated adhesions (2010) (206)
Geometry regulates traction stresses in adherent cells. (2014) (204)
Spatiotemporal constraints on the force-dependent growth of focal adhesions. (2011) (202)
Relating microstructure to rheology of a bundled and cross-linked F-actin network in vitro. (2004) (202)
A zyxin-mediated mechanism for actin stress fiber maintenance and repair. (2010) (200)
Microrheology probes length scale dependent rheology. (2006) (181)
Local Cortical Tension by Myosin II Guides 3D Endothelial Cell Branching (2009) (177)
Stiffness-controlled three-dimensional extracellular matrices for high-resolution imaging of cell behavior (2012) (164)
Epithelial rotation promotes the global alignment of contractile actin bundles during Drosophila egg chamber elongation (2014) (163)
Scaling of F-actin network rheology to probe single filament elasticity and dynamics. (2004) (154)
Stress-dependent elasticity of composite actin networks as a model for cell behavior. (2006) (153)
Chapter 19: Mechanical response of cytoskeletal networks. (2008) (143)
Contractile units in disordered actomyosin bundles arise from F-actin buckling. (2012) (137)
Reconstitution of contractile actomyosin bundles. (2011) (136)
Stressing the limits of focal adhesion mechanosensitivity. (2014) (123)
Transient Frictional Slip between Integrin and the ECM in Focal Adhesions under Myosin II Tension (2010) (116)
Preparation of complaint matrices for quantifying cellular contraction. (2010) (113)
Measuring the mechanical stress induced by an expanding multicellular tumor system: a case study. (2003) (108)
Dynamic and structural signatures of lamellar actomyosin force generation (2011) (101)
Distribution of directional change as a signature of complex dynamics (2013) (97)
Optogenetic control of RhoA reveals zyxin-mediated elasticity of stress fibres (2017) (94)
Assembly Kinetics Determine the Architecture of α-actinin Crosslinked F-actin Networks (2012) (93)
Tunable structure and dynamics of active liquid crystals (2018) (93)
Liquid behavior of cross-linked actin bundles (2017) (91)
Model-based Traction Force Microscopy Reveals Differential Tension in Cellular Actin Bundles (2015) (89)
Lamellipodium is a myosin-independent mechanosensor (2018) (82)
High Throughput Discovery of Functional Protein Modifications by Hotspot Thermal Profiling (2019) (81)
Conserved F-actin dynamics and force transmission at cell adhesions. (2010) (80)
Requirements for contractility in disordered cytoskeletal bundles (2011) (76)
Actin Mechanics and Fragmentation* (2015) (75)
Endothelial barrier disruption and recovery is controlled by substrate stiffness. (2013) (75)
CD98hc (SLC3A2) participates in fibronectin matrix assembly by mediating integrin signaling (2007) (72)
Interplay of structure, elasticity, and dynamics in actin-based nematic materials (2017) (69)
Thick filament length and isoform composition determine self-organized contractile units in actomyosin bundles. (2013) (68)
Mechanical Response of Cytoskeletal Networks (2008) (62)
Optimization of traction force microscopy for micron-sized focal adhesions (2010) (61)
Partitioning and Enhanced Self-Assembly of Actin in Polypeptide Coacervates (2017) (60)
RhoA mediates epithelial cell shape changes via mechanosensitive endocytosis (2019) (58)
Isoforms Confer Characteristic Force Generation and Mechanosensation by Myosin II Filaments. (2015) (56)
The Actin Cytoskeleton as an Active Adaptive Material. (2020) (55)
Liposome adhesion generates traction stress (2014) (54)
Determinants of fluidlike behavior and effective viscosity in cross-linked actin networks. (2012) (54)
Contact guidance requires spatial control of leading-edge protrusion (2017) (53)
Myosin II-Mediated Focal Adhesion Maturation Is Tension Insensitive (2013) (51)
Dynamin regulates the dynamics and mechanical strength of the actin cytoskeleton as a multifilament actin-bundling protein (2020) (50)
Filament rigidity and connectivity tune the deformation modes of active biopolymer networks (2017) (49)
Self-organization of myosin II in reconstituted actomyosin bundles. (2012) (48)
Actomyosin sliding is attenuated in contractile biomimetic cortices (2014) (43)
Cell–substrate interactions (2010) (43)
Mechanosensitive Junction Remodeling Promotes Robust Epithelial Morphogenesis. (2019) (43)
Evolutionarily diverse LIM domain-containing proteins bind stressed actin filaments through a conserved mechanism (2020) (42)
Desmosomal cadherin association with Tctex-1 and cortactin-Arp2/3 drives perijunctional actin polymerization to promote keratinocyte delamination (2018) (41)
Self-organizing motors divide active liquid droplets (2018) (40)
Spatiotemporal control of liquid crystal structure and dynamics through activity patterning (2021) (40)
Attenuation of lipopolysaccharide-induced lung vascular stiffening by lipoxin reduces lung inflammation. (2015) (38)
Filament turnover tunes both force generation and dissipation to control long-range flows in a model actomyosin cortex (2017) (37)
Protrusive activity guides changes in cell-cell tension during epithelial cell scattering. (2014) (37)
Cofilin drives rapid turnover and fluidization of entangled F-actin (2017) (36)
Model for adhesion clutch explains biphasic relationship between actin flow and traction at the cell leading edge (2015) (35)
Arp2/3 Inhibition Induces Amoeboid-Like Protrusions in MCF10A Epithelial Cells by Reduced Cytoskeletal-Membrane Coupling and Focal Adhesion Assembly (2014) (34)
PyK 2 and FAK connections to p 190 Rho guanine nucleotide exchange factor regulate RhoA activity , focal adhesion formation , and cell motility (2008) (33)
Cholesterol depletion impairs contractile machinery in neonatal rat cardiomyocytes (2017) (32)
Machine learning active-nematic hydrodynamics (2020) (31)
Cell cycle–dependent active stress drives epithelia remodeling (2019) (25)
Mechanical hysteresis in actin networks. (2018) (25)
Force localization modes in dynamic epithelial colonies (2018) (23)
Reconstitution of contractile actomyosin arrays. (2014) (20)
A cycling state that can lead to glassy dynamics in intracellular transport (2016) (20)
Shear thickening of F-actin networks crosslinked with non-muscle myosin IIB. (2011) (19)
Dia1-dependent adhesions are required by epithelial tissues to initiate invasion (2018) (18)
Observation and characterization of the vestige of the jamming transition in a thermal three-dimensional system. (2012) (17)
Long Wavelength Spin Dynamics In La0.53Ca0.47MnO3 (1998) (16)
LIM domain proteins in cell mechanobiology (2021) (15)
Fragmentation Partners from Collisional Dissociation of C{sub 60} (1998) (15)
CD 98 hc ( SLC 3 A 2 ) participates in fi bronectin matrix assembly by mediating integrin signaling (2007) (13)
Clutch Dynamics (2008) (10)
Actin assembly factors regulate the gelation kinetics and architecture of F-actin networks. (2013) (10)
Probing intracellular force distributions by high-resolution live cell imaging and inverse dynamics. (2007) (10)
Materials science: Synthetic polymers with biological rigidity (2013) (10)
Tuning shape and internal structure of protein droplets via biopolymer filaments (2019) (8)
Mechanosensitive junction remodelling promotes robust epithelial morphogenesis (2019) (8)
Structuring Stress for Active Materials Control (2019) (8)
Heat and Humidity for Bioburden Reduction of N95 Filtering Facepiece Respirators. (2021) (8)
Force-dependent intercellular adhesion strengthening underlies asymmetric adherens junction contraction (2022) (7)
Optogenetic Control of RhoA to Probe Subcellular Mechanochemical Circuitry (2020) (6)
Tuning molecular motor transport through cytoskeletal filament network organization. (2020) (6)
Cell division Rate Controls Cell Shape Remodeling in Epithelia (2019) (6)
Measuring Cell Mechanics (2015) (6)
Cutting through the noise: the mechanics of intracellular transport. (2014) (6)
Tuning shape and internal structure of protein droplets via biopolymer filaments. (2020) (6)
Actin bundle architecture and mechanics regulate myosin II force generation. (2021) (6)
Tuning molecular motor transport through cytoskeletal filament network organization (2018) (5)
Elasticity of F-actin networks (2004) (5)
Adaptive viscoelasticity of epithelial cell junctions: from models to methods. (2020) (5)
Actin filament alignment causes mechanical hysteresis in cross-linked networks (2021) (4)
Actin bundle architecture and mechanics regulate myosin II force generation (2020) (4)
Moving beyond molecular mechanisms (2015) (4)
High throughput discovery of functional protein modifications by Hotspot Thermal Profiling (2019) (3)
Asymmetric Contraction of Adherens Junctions arises through RhoA and E-cadherin feedback (2021) (3)
Harnessing optogenetics to probe sub-cellular mechanics (2017) (2)
Dia1 coordinates differentiation and cell sorting in a stratified epithelium (2021) (2)
The mechanisms of dynamin-actin interaction (2019) (2)
Nucleation and shape dynamics of model nematic tactoids around adhesive colloids. (2019) (2)
Reconstitution of Actomyosin Bundles (2011) (2)
Force generation by Myosin II Filaments in Compliant Networks (2014) (2)
Actin filament alignment causes mechanical hysteresis in cross-linked networks. (2021) (2)
Force-dependent intercellular adhesion strengthening underlies asymmetric adherens junction contraction (2022) (1)
Liposome Adhesion Generates Contractile Traction Stresses (2015) (1)
Title: Dia1 Coordinates Differentiation and Cell Sorting in a Stratified Epithelium Short Title: Differential Dia1 Expression and Epidermal Cell Sorting (2020) (1)
Catapulting of topological defects through elasticity bands in active nematics. (2022) (1)
Learning to learn: Non-equilibrium design protocols for adaptable materials (2022) (1)
TES-1/Tes and ZYX-1/Zyxin protect junctional actin networks under tension during epidermal morphogenesis in the C. elegans embryo (2022) (1)
The lamellipodium is a myosin independent mechanosensor (2017) (1)
Long Wavelength Spin Dynamics In La/sub 0.53/Ca/sub 0.47/MnO/sub 3/ (1998) (1)
Stress relaxation in F-actin solutions by severing. (2019) (1)
When Is "Enough" Enough? (2017) (1)
Actin Turnover Regulation through Myosin Activity and Network Architecture (2021) (1)
Force generation by Myosin II Filaments on Compliant Substrates (2014) (1)
Encoding Mechano-Memories in Actin Networks (2016) (1)
Active Liquid Crystals with variable Elasticity (2017) (1)
Cellular geometry regulates traction stresses (LB228) (2014) (0)
Rapid non-equilibrium turnover fluidizes entangled F-actin solutions (2016) (0)
Elucidating the consequences of heterogeneous activity in an actin based liquid crystal (2019) (0)
Viscoelastic properties of actin networks influence material transport (2015) (0)
Abstract 1100: Dynamic multicellular mechanics controlling protrusion in 3D. (2013) (0)
Microscopic to mesoscopic: what can modular molecular motors teach us about the nature of active stress? (2020) (0)
Elasticity of Composite Actin Networks (2004) (0)
Impact of filament dynamics on actomyosin flows (2019) (0)
Tunable deformation modes shape contractility in active biopolymer networks (2017) (0)
Exploring Heterogeneities in Actin Networks (2001) (0)
Cell Shape Dependent Motility During the Establishment of Tissue Structure (2019) (0)
Critical forces for actin filament buckling and force transmission influence transport in actomyosin networks (2016) (0)
Enhanced self-assembly of actin encapsulated in polypeptide coacervates (2017) (0)
Integrin Catch Bond Kinetics Mediate Mechanosensing during Cell Spreading (2017) (0)
Modeling F-actin Disassembly by Severing and its Effect on Stress Relaxation (2018) (0)
Actomyosin contraction and adhesion control angiogenic sprouting and guidance (2010) (0)
Force Localization and Cell Shape in Epithelial Monolayers (2017) (0)
Controlling Epithelial Cell Shape (2019) (0)
Quantitative Investigation of Individual Contractile Actin Bundles in vitro (2010) (0)
The Translation of Actin Dynamics into Traction Force via Focal Adhesions in Migrating Cells (2007) (0)
Actin mechanics and fragmentation 1 Actin mechanics and fragmentation (2015) (0)
Traction Force Microscopy Based on an Active Cable Network Model (2014) (0)
Dynamical correlation lengths in shape-based models of confluent tissue (2019) (0)
Regulation of Three-Dimensional Epithelial Cell Shape in a Two-Dimensional Tissue (2021) (0)
New Journal of Physics Requirements for contractility in disordered cytoskeletal bundles (2012) (0)
Mechanisms of Contractility and Coarsening of Active Cytoskeletal Networks (2012) (0)
Regulation of cellular traction force at focal adhesions with spatial constraints (2010) (0)
to be determined by you (2014) (0)
Fluorescent Speckle Microrheology of F-actin Networks (2005) (0)
Modeling and Experimental Investigation of Actin-Myosin and Adhesion Dynamics at the Cell Leading Edge (2012) (0)
Author Correction: Membrane tension induces F-actin reorganization and flow in a biomimetic model cortex (2023) (0)
How Cellular Geometry Regulates Traction Stresses in Adherent Cells (2014) (0)
Helix Insertion Drives Membrane Bending by Enabling Protein Crowding (2015) (0)
Self-Organization in Reconstituted Actomyosin Bundles (2011) (0)
Tension-Dependent Myosin Dynamics on Contractile Actomyosin Structures (2021) (0)
Tuning mechanical relaxation through the regulation of non-equilibrium actin assembly (2014) (0)
Dynamic non-linear response of cross-linked actin networks: an energy dissipation approach (2014) (0)
Shortening actin filaments cause force generation in actomyosin network to change from contractile to extensile (2016) (0)
Quantifying Strain-Sensing Protein Recruitment During Stress Fiber Repair. (2023) (0)
Vestige of T = 0 jamming transition at finite temperature in 3D (2012) (0)
Filament turnover kinetics determine the mechanical relaxation of entangled F-actin solutions (2013) (0)
Visualization of the material response in an actomyosin network at the onset of internal motor activity (2014) (0)
Epithelial Monolayers Display Different Modes of Traction Stress Organization (2018) (0)
Cell Mechanics: The Active Polymer Networks Underlying Force Transmission in Living Cells (2012) (0)
Liquid droplets of cross-linked actin filaments (2017) (0)
Memory Dynamics in Cross-linked Actin Networks (2017) (0)
Force Transmission in a Reconstituted Actomyosin Cortex (2012) (0)
1 Microrheology (2003) (0)
Regulation of myosin II activity by actin architecture (2015) (0)
FIFTEEN Reconstitution of Contractile Actomyosin Arrays (2014) (0)
Tissue confinement regulates cell growth and size in epithelia (2022) (0)
Electron detachment and fragmentation in collisions between 1.25 keV/carbon and clusters and (1999) (0)
Abstract A03: Formins stabilize cell-ECM adhesions during invasion onset (2017) (0)
Mechanics of the Actin Cytoskeleton (2017) (0)
Building active liquid crystals with tunable defect dynamics and variable elasticity (2018) (0)
Force Transmission in the Actin Cytoskeleton (2012) (0)
Living matter—nexus of physics and biology in the 21st century (2012) (0)
Fluorescent Speckle Microrheology (2006) (0)
Margaret Gardel: at the interface of physics and biology. Interview by Caitlin Sedwick. (2013) (0)
Liquid behavior and motor-induced division of actin droplets: a theoretical model (2018) (0)
Confluence and tight junction dependence of volume regulation in epithelial tissue (2022) (0)
HIGH‐THROUGHPUT SCREENING BY TRACTION MICROSCOPY (2013) (0)
Editorial overview: Cell architecture. (2016) (0)
Membrane tension induces F-actin reorganization and flow in a biomimetic model cortex (2023) (0)
Mechanochemical Circuits in the Cytoplasm (2020) (0)
Effects of filament rigidity in myosin II-induced actin network contractility and dynamics (2014) (0)
Zyxin is all you need: machine learning adherent cell mechanics (2023) (0)
Mechanical output of myosin II motors is regulated by myosin filament size and actin network mechanics (2013) (0)
Myosin Isoform-Specificity of Contractile Elements Formed in Reconstituted Actomyosin Bundles (2012) (0)
Cellular geometry regulates traction stresses (479.4) (2014) (0)
Mechanical Hysteresis in Actin Networks : Supplementary information (2018) (0)
Cytoskeletal Regulation of Three-dimensional Epithelial Cell Shape (2020) (0)
A critical tension abrogates nascent adhesion raking against the ECM (2010) (0)
Mechanics of Active Matter Constructed from Actomyosin (2017) (0)
Caveolae Spelunking: Exploring a New Modality in Tensional Homeostasis. (2020) (0)
Control of Topological Defects and Spontaneous Flows in Engineered Active Liquid Crystals (2019) (0)
Encoding mechano-memories in filamentous-actin networks (2017) (0)
Tuning the nature of mechano-memory in actin networks (2018) (0)
The Nanoscale Organization of Focal Adhesion Signaling Complexes can Reflect Changes in Cellular Contractility and Motility (2014) (0)
Reversible mechano-memory in sheared cross-linked actin networks (2015) (0)
Biomimetic Coacervate Environments for Protein Analysis (2015) (0)
Endogenous forces exerted at E-cadherin based cell-cell contacts (2010) (0)
Myosin Regulation of Actin Turnover Dynamics (2020) (0)
Active turnover regulates pattern formation and stress transmission in disordered acto-myosin networks (2017) (0)
TES-1/Tes protects junctional actin networks under tension from self-injury during epidermal morphogenesis in the C. elegans embryo (2021) (0)
The static and dynamic behaviors of the topological defects in a nematic liquid crystal reveal its material characteristics (2017) (0)
Making live-cell imaging glow (2008) (0)
Modeling dividing actomyosin droplets as colloids in liquid crystal (2019) (0)
Desmosomal cadherin association with Tctex-1 and cortactin-Arp2/3 drives perijunctional actin polymerization to promote keratinocyte delamination (2018) (0)
Formin-Dependent Adhesions are Required for Invasion by Epithelial Tissues (2017) (0)
Measuring response functions of active materials from data (2023) (0)

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What Schools Are Affiliated With Margaret Gardel?

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