Maria Grazia Roncarolo

Maria Grazia Roncarolo's AcademicInfluence.com Rankings

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#1411

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#1747

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Pediatrics

#36

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#46

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Maria Grazia Roncarolo

Philosophy

#4772

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#7413

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#2308

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#3275

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Philosophy

Maria Grazia Roncarolo's Degrees

Doctorate Medicine University of Turin
PhD Immunology University of Padua

Why Is Maria Grazia Roncarolo Influential?

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According to Wikipedia, Maria Grazia Roncarolo is an Italian pediatrician who is currently George D. Smith Professor in Stem Cell and Regenerative Medicine and Professor of Medicine at Stanford University. She is also the Director of the Stanford Institute of Stem Cell Biology and Regenerative Medicine along with Irving Weissman and Michael Longaker and the Director for Center for Definitive and Curative Medicine at Stanford.

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Maria Grazia Roncarolo's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

A CD4+T-cell subset inhibits antigen-specific T-cell responses and prevents colitis (1997) (4062)
Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression (1991) (2036)
Interleukin‐10‐secreting type 1 regulatory T cells in rodents and humans (2006) (1257)
Correction of ADA-SCID by Stem Cell Gene Therapy Combined with Nonmyeloablative Conditioning (2002) (1143)
Human Cd25+Cd4+ T Regulatory Cells Suppress Naive and Memory T Cell Proliferation and Can Be Expanded in Vitro without Loss of Function (2001) (1129)
Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells. (2005) (1115)
Lentiviral Hematopoietic Stem Cell Gene Therapy Benefits Metachromatic Leukodystrophy (2013) (1030)
Gene therapy for immunodeficiency due to adenosine deaminase deficiency. (2009) (926)
Type 1 T regulatory cells (2001) (888)
Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine production. (2007) (888)
Interleukin-10 induces a long-term antigen-specific anergic state in human CD4+ T cells (1996) (861)
Lentiviral Hematopoietic Stem Cell Gene Therapy in Patients with Wiskott-Aldrich Syndrome (2013) (812)
Rapamycin Promotes Expansion of Functional CD4+CD25+FOXP3+ Regulatory T Cells of Both Healthy Subjects and Type 1 Diabetic Patients1 (2006) (678)
Coexpression of CD49b and LAG-3 identifies human and mouse T regulatory type 1 cells (2013) (648)
IFN-α and IL-10 Induce the Differentiation of Human Type 1 T Regulatory Cells1 (2001) (602)
Th17 cells express interleukin-10 receptor and are controlled by Foxp3⁻ and Foxp3+ regulatory CD4+ T cells in an interleukin-10-dependent manner. (2011) (560)
Regulatory T-cell immunotherapy for tolerance to self antigens and alloantigens in humans (2007) (555)
Differentiation of T Regulatory Cells by Immature Dendritic Cells (2001) (551)
Regulatory T cells: recommendations to simplify the nomenclature (2013) (536)
Reprogramming human T cell function and specificity with non-viral genome targeting (2017) (503)
Defective regulatory and effector T cell functions in patients with FOXP3 mutations. (2006) (501)
Differentiation of Tr1 cells by immature dendritic cells requires IL-10 but not CD25+CD4+ Tr cells. (2005) (498)
Differentiation of type 1 T regulatory cells (Tr1) by tolerogenic DC-10 requires the IL-10-dependent ILT4/HLA-G pathway. (2010) (497)
Human CD25+CD4+ T Suppressor Cell Clones Produce Transforming Growth Factor β, but not Interleukin 10, and Are Distinct from Type 1 T Regulatory Cells (2002) (484)
The role of 2 FOXP3 isoforms in the generation of human CD4+ Tregs. (2005) (459)
High levels of interleukin 10 production in vivo are associated with tolerance in SCID patients transplanted with HLA mismatched hematopoietic stem cells (1994) (424)
The Role of IL-10 and TGF-β in the Differentiation and Effector Function of T Regulatory Cells (2002) (423)
IL-10 is produced by subsets of human CD4+ T cell clones and peripheral blood T cells. (1992) (415)
Strategies of Anti‐Cytokine Monoclonal Antibody Development: Immunoassay of IL‐10 and IL‐5 in Clinical Samples (1992) (406)
Inhibitory and stimulatory effects of IL-10 on human CD8+ T cells. (1998) (387)
The role of different subsets of T regulatory cells in controlling autoimmunity. (2000) (358)
Identification of a common T/natural killer cell progenitor in human fetal thymus (1994) (336)
Human B cell clones can be induced to proliferate and to switch to IgE and IgG4 synthesis by interleukin 4 and a signal provided by activated CD4+ T cell clones (1991) (330)
Lentiviral haemopoietic stem-cell gene therapy in early-onset metachromatic leukodystrophy: an ad-hoc analysis of a non-randomised, open-label, phase 1/2 trial (2016) (322)
IFN-alpha and IL-10 induce the differentiation of human type 1 T regulatory cells. (2001) (321)
Treatment of X-linked severe combined immunodeficiency by in utero transplantation of paternal bone marrow. (1996) (312)
A transgenic model to analyze the immunoregulatory role of IL-10 secreted by antigen-presenting cells. (1999) (283)
Tr1 cells: from discovery to their clinical application. (2006) (280)
Multilineage hematopoietic reconstitution without clonal selection in ADA-SCID patients treated with stem cell gene therapy. (2007) (253)
Role of regulatory T cells and FOXP3 in human diseases. (2007) (251)
From IPEX syndrome to FOXP3 mutation: a lesson on immune dysregulation (2018) (248)
CD4+ T‐regulatory cells: toward therapy for human diseases (2008) (238)
Induction of CD4+ T cell alloantigen-specific hyporesponsiveness by IL-10 and TGF-beta. (1999) (230)
Targeting lentiviral vector expression to hepatocytes limits transgene-specific immune response and establishes long-term expression of human antihemophilic factor IX in mice. (2004) (225)
Growth and expansion of human T regulatory type 1 cells are independent from TCR activation but require exogenous cytokines (2002) (213)
Recent advances in understanding the pathophysiology of Wiskott-Aldrich syndrome. (2009) (213)
Generation of potent and stable human CD4+ T regulatory cells by activation-independent expression of FOXP3. (2008) (212)
Wiskott-Aldrich syndrome protein regulates lipid raft dynamics during immunological synapse formation. (2002) (211)
Immune reconstitution in ADA-SCID after PBL gene therapy and discontinuation of enzyme replacement (2002) (209)
CD4+ regulatory T cells: mechanisms of induction and effector function. (2005) (209)
Long-term follow-up of IPEX syndrome patients after different therapeutic strategies: An international multicenter retrospective study (2017) (205)
Erratum: Interleukin-10- secreting type 1 regulatory T cells in rodents and humans (Immunological Reviews (2006) 212, (28-50)) (2006) (202)
Rapamycin and interleukin-10 treatment induces T regulatory type 1 cells that mediate antigen-specific transplantation tolerance. (2006) (201)
Clinical and molecular profile of a new series of patients with immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome: inconsistent correlation between forkhead box protein 3 expression and disease severity. (2008) (200)
IL-10 and TGF-beta induce alloreactive CD4+CD25- T cells to acquire regulatory cell function. (2003) (197)
T-regulatory 1 cells: a novel subset of CD4 T cells with immunoregulatory properties. (2000) (193)
In vivo administration of lentiviral vectors triggers a type I interferon response that restricts hepatocyte gene transfer and promotes vector clearance. (2007) (193)
Tr1 cells and the counter-regulation of immunity: natural mechanisms and therapeutic applications. (2014) (193)
Gene therapy for ADA‐SCID, the first marketing approval of an ex vivo gene therapy in Europe: paving the road for the next generation of advanced therapy medicinal products (2017) (186)
A proportion of patients with lymphoma may harbor mutations of the perforin gene. (2004) (184)
STAT5-signaling cytokines regulate the expression of FOXP3 in CD4+CD25+ regulatory T cells and CD4+CD25- effector T cells. (2008) (182)
Is FOXP3 a bona fide marker for human regulatory T cells? (2008) (180)
WASP regulates suppressor activity of human and murine CD4+CD25+FOXP3+ natural regulatory T cells (2007) (176)
Impaired humoral immunity in X-linked lymphoproliferative disease is associated with defective IL-10 production by CD4+ T cells. (2005) (176)
Loss of mismatched HLA in leukemia after stem-cell transplantation. (2009) (175)
Update on the safety and efficacy of retroviral gene therapy for immunodeficiency due to adenosine deaminase deficiency. (2016) (174)
SAP controls the cytolytic activity of CD8+ T cells against EBV-infected cells. (2005) (171)
Induction of Tolerance in Type 1 Diabetes via Both CD4+CD25+ T Regulatory Cells and T Regulatory Type 1 Cells (2006) (171)
In Vivo Tracking of Human Hematopoiesis Reveals Patterns of Clonal Dynamics during Early and Steady-State Reconstitution Phases (2016) (168)
The Biology of T Regulatory Type 1 Cells and Their Therapeutic Application in Immune-Mediated Diseases. (2018) (167)
Human IL2RA null mutation mediates immunodeficiency with lymphoproliferation and autoimmunity (2013) (162)
Activation of the aryl hydrocarbon receptor promotes allograft-specific tolerance through direct and dendritic cell-mediated effects on regulatory T cells. (2008) (160)
Recombinant human interleukin 10 suppresses gliadin dependent T cell activation in ex vivo cultured coeliac intestinal mucosa (2004) (146)
The Cellular and Molecular Mechanisms of Immuno-Suppression by Human Type 1 Regulatory T Cells (2011) (142)
In vivo delivery of a microRNA-regulated transgene induces antigen-specific regulatory T cells and promotes immunologic tolerance. (2009) (141)
Gene correction for SCID-X1 in long-term hematopoietic stem cells (2018) (141)
Hepatocyte-Targeted Expression by Integrase-Defective Lentiviral Vectors Induces Antigen-Specific Tolerance in Mice with Low Genotoxic Risk (2011) (141)
In vivo tracking of T cells in humans unveils decade-long survival and activity of genetically modified T memory stem cells (2014) (139)
Hurdles in therapy with regulatory T cells (2015) (138)
Interleukin 10 inhibits allogeneic proliferative and cytotoxic T cell responses generated in primary mixed lymphocyte cultures. (1992) (134)
Gliadin-Specific Type 1 Regulatory T Cells from the Intestinal Mucosa of Treated Celiac Patients Inhibit Pathogenic T Cells (2006) (132)
Rapamycin Monotherapy in Patients With Type 1 Diabetes Modifies CD4+CD25+FOXP3+ Regulatory T-Cells (2008) (131)
Killing of myeloid APCs via HLA class I, CD2 and CD226 defines a novel mechanism of suppression by human Tr1 cells (2011) (130)
Expression of CD33, CD38, and HLA-DR on CD34+ human fetal liver progenitors with a high proliferative potential. (1994) (129)
Immunological Outcome in Haploidentical-HSC Transplanted Patients Treated with IL-10-Anergized Donor T Cells (2013) (128)
Lentiviral haemopoietic stem/progenitor cell gene therapy for treatment of Wiskott-Aldrich syndrome: interim results of a non-randomised, open-label, phase 1/2 clinical study (2019) (125)
Temporal, quantitative, and functional characteristics of single-KIR-positive alloreactive natural killer cell recovery account for impaired graft-versus-leukemia activity after haploidentical hematopoietic stem cell transplantation. (2008) (124)
Gene Therapy. (2019) (123)
Lentiviral vectors targeting WASp expression to hematopoietic cells, efficiently transduce and correct cells from WAS patients (2007) (120)
IN-UTERO TRANSPLANTATION OF STEM CELLS IN BARE LYMPHOCYTE SYNDROME (1989) (119)
Differentiation of Tr 1 cells by immature dendritic cells requires IL-10 but not CD 25 CD 4 Tr cells (2005) (118)
Lentiviral vector-mediated gene transfer in T cells from Wiskott-Aldrich syndrome patients leads to functional correction. (2004) (118)
CD4+ T Cells from IPEX Patients Convert into Functional and Stable Regulatory T Cells by FOXP3 Gene Transfer (2013) (114)
A hypomorphic R229Q Rag2 mouse mutant recapitulates human Omenn syndrome. (2007) (112)
Italian cancer figures, report 2012: Cancer in children and adolescents. (2013) (111)
FLK-2/FLT-3 ligand regulates the growth of early myeloid progenitors isolated from human fetal liver. (1995) (111)
Interleukin-10 dose-dependent regulation of CD4+ and CD8+ T cell-mediated graft-versus-host disease. (1998) (108)
Sirolimus-based graft-versus-host disease prophylaxis promotes the in vivo expansion of regulatory T cells and permits peripheral blood stem cell transplantation from haploidentical donors (2014) (106)
Ten years of gene therapy for primary immune deficiencies. (2009) (106)
Defective Th1 Cytokine Gene Transcription in CD4+ and CD8+ T Cells from Wiskott-Aldrich Syndrome Patients1 (2006) (103)
Host-reactive CD4+ and CD8+ T cell clones isolated from a human chimera produce IL-5, IL-2, IFN-gamma and granulocyte/macrophage-colony-stimulating factor but not IL-4. (1990) (103)
Immune responses by cord blood cells. (1994) (102)
HLA-G expressing DC-10 and CD4+ T cells accumulate in human decidua during pregnancy (2013) (98)
Alterations in the adenosine metabolism and CD39/CD73 adenosinergic machinery cause loss of Treg cell function and autoimmunity in ADA-deficient SCID. (2012) (98)
Integration profile of retroviral vector in gene therapy treated patients is cell-specific according to gene expression and chromatin conformation of target cell (2011) (96)
Health related quality of life in Middle Eastern children with beta-thalassemia (2012) (94)
Genomic organization of the human T-cell antigen-receptor alpha/delta locus. (1988) (91)
Phenotypic and functional differences between human CD4+CD25+ and type 1 regulatory T cells. (2005) (90)
Stability of human rapamycin-expanded CD4+CD25+ T regulatory cells (2011) (90)
Evidence for long-term efficacy and safety of gene therapy for Wiskott-Aldrich syndrome in preclinical models. (2009) (90)
Correction of β-thalassemia major by gene transfer in haematopoietic progenitors of pediatric patients (2010) (88)
Transgene Expression of bcl-xL Permits Anti-immunoglobulin (Ig)–induced Proliferation in xid B Cells (1998) (85)
Ex vivo gene therapy with lentiviral vectors rescues adenosine deaminase (ADA)-deficient mice and corrects their immune and metabolic defects. (2006) (85)
Efficacy of gene therapy for Wiskott-Aldrich syndrome using a WAS promoter/cDNA-containing lentiviral vector and nonlethal irradiation. (2006) (84)
Phenotypic and functional analysis of T-cell precursors in the human fetal liver and thymus: CD7 expression in the early stages of T- and myeloid-cell development (1993) (83)
Functional type 1 regulatory T cells develop regardless of FOXP3 mutations in patients with IPEX syndrome (2011) (83)
High spontaneous IL-10 production in unrelated bone marrow transplant recipients is associated with fewer transplant-related complications and early deaths (1999) (80)
Peripheral blood lymphocytes of patients with common variable immunodeficiency (CVI) produce reduced levels of interleukin-4, interleukin-2 and interferon-gamma, but proliferate normally upon activation by mitogens. (1989) (79)
Natural killer cell clones can efficiently process and present protein antigens. (1991) (79)
Tregopathies: Monogenic diseases resulting in regulatory T‐cell deficiency (2018) (77)
ADA-deficient SCID is associated with a specific microenvironment and bone phenotype characterized by RANKL/OPG imbalance and osteoblast insufficiency. (2009) (76)
Integration of retroviral vectors induces minor changes in the transcriptional activity of T cells from ADA-SCID patients treated with gene therapy. (2009) (74)
Altered intracellular and extracellular signaling leads to impaired T-cell functions in ADA-SCID patients. (2008) (72)
Clinical tolerance in allogeneic hematopoietic stem cell transplantation (2011) (72)
Molecular and functional heterogeneity of IL-10-producing CD4+ T cells (2018) (70)
Antigen recognition by MHC-incompatible cells of a human mismatched chimera (1988) (69)
Preclinical Safety and Efficacy of Human CD34+ Cells Transduced With Lentiviral Vector for the Treatment of Wiskott-Aldrich Syndrome (2012) (69)
A novel function for FOXP3 in humans: intrinsic regulation of conventional T cells. (2013) (68)
Induction of isotype switching and Ig production by CD5+ and CD10+ human fetal B cells. (1992) (67)
An anti-CD45RO/RB monoclonal antibody modulates T cell responses via induction of apoptosis and generation of regulatory T cells (2005) (66)
Antigen-Specific Dependence of Tr1-Cell Therapy in Preclinical Models of Islet Transplant (2009) (66)
Demethylation analysis of the FOXP3 locus shows quantitative defects of regulatory T cells in IPEX-like syndrome (2012) (64)
CRISPR-based gene editing enables FOXP3 gene repair in IPEX patient cells (2020) (63)
Phenotypic and functional evidence for the expression of CD4 by hematopoietic stem cells isolated from human fetal liver. (1997) (62)
The FLK2/FLT3 ligand synergizes with interleukin-7 in promoting stromal-cell-independent expansion and differentiation of human fetal pro-B cells in vitro. (1996) (62)
Molecular and functional characterization of allogantigen-specific anergic T cells suitable for cell therapy (2010) (61)
HLA-G expression levels influence the tolerogenic activity of human DC-10 (2015) (60)
Type 1 regulatory T cells are associated with persistent split erythroid/lymphoid chimerism after allogeneic hematopoietic stem cell transplantation for thalassemia (2009) (59)
Type 1 T regulatory cells and their relationship with CD4+CD25+ T regulatory cells. (2003) (59)
The Wiskott-Aldrich syndrome protein is required for iNKT cell maturation and function (2009) (58)
Enforced IL-10 expression confers type 1 regulatory T cell (Tr1) phenotype and function to human CD4(+) T cells. (2012) (57)
The role of interleukin 10 in the control of autoimmunity. (2003) (57)
Altered T-cell receptor + CD28-mediated signaling and blocked cell cycle progression in interleukin 10 and transforming growth factor-beta-treated alloreactive T cells that do not induce graft-versus-host disease. (2001) (56)
Induction of anergic allergen-specific suppressor T cells using tolerogenic dendritic cells derived from children with allergies to house dust mites. (2010) (55)
Granulocyte-colony stimulating factor drives the in vitro differentiation of human dendritic cells that induce anergy in naïve T cells (2010) (55)
Induction of human T helper cell type 1 differentiation results in loss of IFN-gamma receptor beta-chain expression. (1997) (55)
Identity and Diversity of Human Peripheral Th and T Regulatory Cells Defined by Single-Cell Mass Cytometry (2018) (55)
Liver gene therapy by lentiviral vectors reverses anti-factor IX pre-existing immunity in haemophilic mice (2013) (54)
Clinical Outlook for Type-1 and FOXP3+ T Regulatory Cell-Based Therapy (2015) (53)
Generation of primary antigen-specific human T- and B-cell responses in immunocompetent SCID-hu mice (2000) (53)
Clonal analysis of the peripheral T cell compartment of the SCID-hu mouse. (1991) (53)
Tracing the expression of CD7 and other antigens during T- and myeloid-cell differentiation in the human fetal liver and thymus. (1995) (52)
The role of 2 FOXP 3 isoforms in the generation of human CD 4 + Tregs (2005) (52)
Prospective assessment of health-related quality of life in pediatric patients with beta-thalassemia following hematopoietic stem cell transplantation. (2011) (52)
Development of lentiviral gene therapy for Wiskott Aldrich syndrome (2008) (52)
Autoreactive T cell clones specific for class I and class II HLA antigens isolated from a human chimera (1988) (52)
Insulin B chain 9–23 gene transfer to hepatocytes protects from type 1 diabetes by inducing Ag-specific FoxP3+ Tregs (2015) (52)
Engineered T Regulatory Type 1 Cells for Clinical Application (2018) (51)
Frequency and targeted detection of HLA-DPB1 T cell epitope disparities relevant in unrelated hematopoietic stem cell transplantation. (2007) (51)
The FLK2/FLT3 ligand synergizes with interleukin-7 in promoting stromal- cell-independent expansion and differentiation of human fetal pro-B cells in vitro (1996) (51)
Isolation, expansion, and characterization of human natural and adaptive regulatory T cells. (2007) (51)
Immune intervention with T regulatory cells: past lessons and future perspectives for type 1 diabetes. (2011) (51)
Therapeutic applications for hematopoietic stem cell gene transfer (2002) (50)
B-cell reconstitution after lentiviral vector–mediated gene therapy in patients with Wiskott-Aldrich syndrome (2015) (48)
Gene Therapy for Adenosine Deaminase Deficiency: A Comprehensive Evaluation of Short- and Medium-Term Safety (2018) (48)
Cord blood B cells are mature in their capacity to switch to IgE‐producing cells in response to interleukin‐4 in vitro (1990) (48)
High incidence of severe cyclosporine neurotoxicity in children affected by haemoglobinopaties undergoing myeloablative haematopoietic stem cell transplantation: early diagnosis and prompt intervention ameliorates neurological outcome (2010) (47)
Absence of VOD in paediatric thalassaemic HSCT recipients using defibrotide prophylaxis and intravenous Busulphan (2009) (47)
Forkhead box protein 3 (FOXP3) mutations lead to increased TH17 cell numbers and regulatory T-cell instability. (2011) (47)
In utero transplantation of stem cells in humans: immunological aspects and clinical follow-up of patients. (1992) (46)
Development of β-globin gene correction in human hematopoietic stem cells as a potential durable treatment for sickle cell disease (2021) (45)
Wild-type FOXP3 is selectively active in CD4+CD25(hi) regulatory T cells of healthy female carriers of different FOXP3 mutations. (2009) (45)
Second hematopoietic SCT in patients with thalassemia recurrence following rejection of the first graft (2008) (45)
Point mutants of forkhead box P3 that cause immune dysregulation, polyendocrinopathy, enteropathy, X-linked have diverse abilities to reprogram T cells into regulatory T cells. (2010) (44)
Role of human leukocyte antigen-G in the induction of adaptive type 1 regulatory T cells. (2009) (44)
HIV-1-derived lentiviral vectors directly activate plasmacytoid dendritic cells, which in turn induce the maturation of myeloid dendritic cells. (2011) (43)
Rapamycin Prevents and Breaks the Anti-CD3–Induced Tolerance in NOD Mice (2009) (43)
The Tregs' world according to GARP (2009) (42)
Membranes of activated CD4+ T cells expressing T cell receptor (TcR) αβ or TcR γδ induce IgE synthesis by human B cells in the presence of interleukin‐4 (1992) (41)
Human insulin production and amelioration of diabetes in mice by electrotransfer-enhanced plasmid DNA gene transfer to the skeletal muscle (2002) (41)
Transplant Tolerance to Pancreatic Islets Is Initiated in the Graft and Sustained in the Spleen (2013) (41)
Gene therapy for primary immunodeficiency. (1995) (41)
Fetal tissue transplantation, bone marrow transplantation and prospective gene therapy in severe immunodeficiencies and enzyme deficiencies. (1987) (41)
Gene therapy for adenosine deaminase deficiency (2003) (40)
Minimum Information about T Regulatory Cells: A Step toward Reproducibility and Standardization (2018) (39)
Genome editing of donor-derived T-cells to generate allogenic chimeric antigen receptor-modified T cells: Optimizing αβ T cell-depleted haploidentical hematopoietic stem cell transplantation. (2020) (39)
Lentiviral-mediated gene therapy leads to improvement of B-cell functionality in a murine model of Wiskott-Aldrich syndrome. (2011) (39)
Lentiviral Gene Therapy in HSCs Restores Lineage-Specific Foxp3 Expression and Suppresses Autoimmunity in a Mouse Model of IPEX Syndrome. (2019) (39)
The immune response to lentiviral-delivered transgene is modulated in vivo by transgene-expressing antigen-presenting cells but not by CD4+CD25+ regulatory T cells. (2007) (38)
Chimerism and tolerance to host and donor in severe combined immunodeficiencies transplanted with fetal liver stem cells. (1993) (38)
Revertant T lymphocytes in a patient with Wiskott-Aldrich syndrome: analysis of function and distribution in lymphoid organs. (2010) (36)
Unpredictability of intravenous busulfan pharmacokinetics in children undergoing hematopoietic stem cell transplantation for advanced beta thalassemia: limited toxicity with a dose-adjustment policy. (2010) (36)
Inducing and enhancing effects of IL-3, -5, and -6 and GM-CSF on histamine release from human basophils. (1993) (36)
Enforced IL-10 Expression Confers Type 1 Regulatory T Cell (Tr1) Phenotype and Function to Human CD4+ T Cells. (2012) (35)
Coexpression of CD163 and CD141 identifies human circulating IL-10-producing dendritic cells (DC-10) (2019) (35)
Rapamycin Combined with Anti-CD45RB mAb and IL-10 or with G-CSF Induces Tolerance in a Stringent Mouse Model of Islet Transplantation (2011) (35)
Forkhead box P3: The Peacekeeper of the Immune System (2014) (35)
Beneficial autoimmunity in Type 1 diabetes mellitus. (2005) (34)
Toxicity-Free Hematopoietic Stem Cell Engraftment Achieved with Anti-CD117 Monoclonal Antibody Conditioning (2019) (34)
Hematopoietic stem cell gene therapy for adenosine deaminase deficient-SCID (2009) (34)
IL-10-Engineered Human CD4+ Tr1 Cells Eliminate Myeloid Leukemia in an HLA Class I-Dependent Mechanism (2017) (34)
The fate of human Treg cells. (2009) (34)
The role of cytokines (and not only) in inducing and expanding T regulatory type 1 cells. (2004) (34)
Fetal liver transplantation: biology and clinical results. (1993) (34)
Fatal autoimmunity in mice reconstituted with human hematopoietic stem cells encoding defective FOXP3. (2015) (33)
The puzzling world of murine T regulatory cells. (2002) (33)
Treatment with Rapamycin Can Restore Regulatory T Cell Function in IPEX Patients. (2019) (33)
Cooperation between major histocompatibility complex mismatched mononuclear cells from a human chimera in the production of antigen-specific antibody. (1986) (32)
Peanut‐specific type 1 regulatory T cells induced in vitro from allergic subjects are functionally impaired (2018) (32)
Human Ig production and isotype switching in severe combined immunodeficient-human mice. (1993) (30)
Methods for in vitro generation of human type 1 regulatory T cells. (2011) (30)
Preclinical Safety and Efficacy of Human CD34+ Cells Transduced With Lentiviral Vector for the Treatment of Wiskott-Aldrich Syndrome. (2013) (29)
Reappraisal of in utero Stem Cell Transplantation Based on Long-Term Results (2004) (29)
Graft Engineering and Adoptive Immunotherapy: New Approaches to Promote Immune Tolerance After Hematopoietic Stem Cell Transplantation (2019) (29)
B-cell development and functions and therapeutic options in adenosine deaminase-deficient patients. (2014) (28)
Studies of EBV-lymphoid cell interactions in two patients with the X-linked lymphoproliferative syndrome: normal EBV-specific HLA-restricted cytotoxicity. (1986) (28)
Phenotypic and functional analysis of T-cell precursors in the human fetal liver and thymus: CD7 expression in the early stages of T- and myeloid-cell development. (1993) (27)
IL-10 transgenic mice present a defect in T cell development reminiscent of SCID patients. (1999) (27)
Diabetic Patients T Cells of Both Healthy Subjects and Type 1 Regulatory + FOXP 3 + CD 25 + Functional CD 4 Rapamycin Promotes Expansion of Roncarolo (2006) (27)
Characterization of new arylsulfatase A gene mutations reinforces genotype‐phenotype correlation in metachromatic leukodystrophy (2009) (27)
Role of regulatory T cells and FOXP 3 in human diseases (26)
Rapamycin Monotherapy in Patients With Type 1 Diabetes Modifies CD4CD25FOXP3 Regulatory (2008) (26)
Platelet transfusion refractoriness in highly immunized beta thalassemia children undergoing stem cell transplantation (2010) (25)
In utero transplantation of hemopoietic stem cells in humans. (1991) (24)
Induction of transplantation tolerance via regulatory T cells. (2006) (24)
Regulatory Roles of the Ligand for Flk2/Flt3 Tyrosine Kinase Receptor on Human Hematopoiesis (1996) (23)
Immune responses in liver-directed lentiviral gene therapy. (2013) (23)
Dysfunctional cytokine production by host-reactive T-cell clones isolated from a chimeric severe combined immunodeficiency patient transplanted with haploidentical bone marrow. (1995) (22)
Escalating doses of donor lymphocytes for incipient graft rejection following SCT for thalassemia (2010) (22)
Colony-forming cells expressing high levels of CD34 are the main targets for granulocyte colony-stimulating factor and macrophage colony-stimulating factor in the human fetal liver. (1997) (22)
Regulatory T cells: prospective for clinical application in hematopoietic stem cell transplantation (2005) (22)
Gene Therapy for Wiskott-Aldrich Syndrome: History, New Vectors, Future Directions. (2020) (21)
Immune functions of cord blood cells before and after transplantation. (1996) (21)
Role of reduced intensity conditioning in T-cell and B-cell immune reconstitution after HLA-identical bone marrow transplantation in ADA-SCID (2010) (20)
Genotypes and haplotypes in the 3' untranslated region of the HLA-G gene and their association with clinical outcome of hematopoietic stem cell transplantation for beta-thalassemia. (2012) (20)
Progress in the ex vivo expansion of hematopoietic progenitors. (1994) (20)
Manipulating Immune Tolerance with Micro-RNA Regulated Gene Therapy (2011) (19)
Author Correction: Gene correction for SCID-X1 in long-term hematopoietic stem cells (2019) (19)
Reciprocal hybrid joints demonstrate successive V-J rearrangements on the same chromosome in the human TCR gamma locus. (1991) (19)
Ectopic FOXP3 Expression Preserves Primitive Features Of Human Hematopoietic Stem Cells While Impairing Functional T Cell Differentiation (2017) (18)
IL-3 or IL-7 increases ex vivo gene transfer efficiency in ADA-SCID BM CD34+ cells while maintaining in vivo lymphoid potential. (2004) (17)
HLA-haploidentical umbilical cord blood stem cell transplantation in a child with advanced leukemia: clinical outcome and analysis of hematopoietic recovery. (1995) (17)
Progress and prospects: gene therapy clinical trials (part 1) (2007) (17)
First Occurrence of Plasmablastic Lymphoma in Adenosine Deaminase-Deficient Severe Combined Immunodeficiency Disease Patient and Review of the Literature (2018) (16)
Alloantigen-specific type 1 regulatory T cells suppress through CTLA-4 and PD-1 pathways and persist long-term in patients (2021) (16)
Bone marrow as a source of hematopoietic stem cells for human gene therapy of β-thalassemia. (2011) (16)
Human‐engineered Treg‐like cells suppress FOXP3‐deficient T cells but preserve adaptive immune responses in vivo (2020) (16)
Do human TH1 and TH2 CD4+ clones exist? (1991) (16)
Presence of Host‐Reactive and MHC‐Restricted T Cells in a Transplanted Severe Combined Immunodeficient (SCID) Patient Suggest Positive Selection and Absence of Clonal Deletion (1990) (16)
Mobilized blood CD34+ cells transduced and selected with a clinically applicable protocol reconstitute lymphopoiesis in SCID-Hu mice. (2004) (16)
Molecular regulation of cellular immunity by FOXP3. (2009) (16)
INDUCTION OF TRANSPLANTATION TOLERANCE IN HUMANS USING FETAL CELL TRANSPLANTS (2004) (15)
Mixed chimerism evolution is associated with T regulatory type 1 (Tr1) cells in a β-thalassemic patient after haploidentical haematopoietic stem cell transplantation (2014) (14)
Author Correction: Gene correction for SCID-X1 in long-term hematopoietic stem cells (2019) (14)
Regulation of human IgE synthesis: the role of CD4+ and CD8+ T-cells and the inhibitory effects of interferon-alpha. (1991) (13)
Role of human forkhead box P3 in early thymic maturation and peripheral T‐cell homeostasis (2018) (13)
Interleukin-10 Anergized Donor T Cell Infusion Improves Immune Reconstitution without Severe Graft-Versus-Host-Disease After Haploidentical Hematopoietic Stem Cell Transplantation. (2009) (13)
Autoimmune diabetic patients undergoing allogeneic islet transplantation: are we ready for a regulatory T-cell therapy? (2009) (13)
APVO210: A Bispecific Anti-CD86-IL-10 Fusion Protein (ADAPTIR™) to Induce Antigen-Specific T Regulatory Type 1 Cells (2018) (13)
2018 CIS Annual Meeting: Immune Deficiency & Dysregulation North American Conference (2018) (13)
Construction of Human‐SCID Chimeric Mice (1998) (13)
Human CD4+ regulatory T cells and activation-induced tolerance. (2005) (13)
In vivo T-cell dynamics during immune reconstitution after hematopoietic stem cell gene therapy in adenosine deaminase severe combined immune deficiency. (2011) (13)
Re-establishing immune tolerance in type 1 diabetes via regulatory T cells. (2008) (13)
The Yin and Yang of Type 1 Regulatory T Cells: From Discovery to Clinical Application (2021) (12)
Concise Review: Cell‐Based Therapies and Other Non‐Traditional Approaches for Type 1 Diabetes (2016) (12)
Non-Genotoxic Anti-CD117 Antibody Conditioning Results in Successful Hematopoietic Stem Cell Engraftment in Patients with Severe Combined Immunodeficiency (2019) (11)
A novel human packaging cell line with hematopoietic supportive capacity increases gene transfer into early hematopoietic progenitors. (2001) (11)
Type 1 regulatory T (Tr1) cells: from the bench to the bedside (2012) (11)
Molecular purging of multiple myeloma cells by ex-vivo culture and retroviral transduction of mobilized-blood CD34+ cells (2007) (10)
Current reviews of allergy and clinical immunology (2007) (10)
Immunological lessons learnt from patients transplanted with fully mismatched stem cells (2007) (10)
Interleukin-4 suppresses immunoglobulin production by peripheral blood lymphocytes of patients with common variable immunodeficiency (CVI) induced by supernatants of T cell clones. (1989) (10)
Membranes of activated CD4+ T cells expressing T cell receptor (TcR) alpha beta or TcR gamma delta induce IgE synthesis by human B cells in the presence of interleukin-4. (1992) (10)
T‐Cell Subsets and Their Cytokine Profiles in Transplantation and Tolerance (1995) (9)
Dendritic cell functional improvement in a preclinical model of lentiviral-mediated gene therapy for Wiskott-Aldrich syndrome (2011) (9)
Fatal vancomycin- and linezolid-resistant Enterococcus faecium sepsis in a child undergoing allogeneic haematopoietic stem cell transplantation for beta-thalassaemia major. (2010) (9)
Long-Term Safety and Efficacy of Gene Therapyfor Adenosine Deaminase (ADA)-Deficient Severe Combined Immunodeficiency (2009) (9)
Unmatched stem cell transplantation as a possible alternative to bone marrow transplantation. (1989) (8)
Utilizing regulatory T cells to control alloreactivity. (2005) (8)
A SCID patient reconstituted with HLA-incompatible fetal stem cells as a model for studying transplantation tolerance. (1991) (8)
Phenotypic and Functional Evidence for the Expression of CD 4 by Hematopoietic Stem Cells Isolated From Human Fetal Liver (1997) (7)
Human Hematopoiesis in SCID Mice (1995) (7)
Interleukin-10 and Transplantation Tolerance (1995) (7)
The capacity of interleukin‐4 to induce in vitro IgE synthesis by B cells of patients with common variable immunodeficiency (1990) (7)
Lentiviral Mediated Gene Therapy for Pyruvate Kinase Deficiency: A Global Phase 1 Study for Adult and Pediatric Patients (2020) (7)
Wild-type FOXP 3 is selectively active in CD 4 CD 25 hi regulatory T cells of healthy female carriers of different FOXP 3 mutations (2009) (7)
T lymphocytes from human chimeras do recognize antigen in the context of allogeneic determinants of the major histocompatibility complex. (1993) (6)
SCID-hu mice as a model to study tolerance after fetal stem cell transplantation. (1992) (6)
New developments in stem cell transplantation with special reference to the first in utero transplants in humans. (1991) (6)
Multiple BM harvests in pediatric donors for thalassemic siblings: safety, efficacy and ethical issues (2008) (6)
InsB9-23 Gene Transfer To Hepatocytes-Based Combined Therapy Abrogates Recurrence of Type-1 Diabetes After Islet Transplantation. (2020) (6)
T cell receptor‐dependent activation of human lymphocytes through cell surface ganglioside GT1b: implications for innate immunity (2000) (6)
Safety and Clinical Benefit of Lentiviral Hematopoietic Stem Cell Gene Therapy for Wiskott-Aldrich Syndrome (2015) (6)
Driving Medical Innovation Through Interdisciplinarity: Unique Opportunities and Challenges (2019) (6)
Clinical improvement and normalized Th1 cytokine profile in early and long‐term interferon‐α treatment in a suspected case of hyper‐IgE syndrome (2008) (6)
Lentiviral Mediated Gene Therapy for Pyruvate Kinase Deficiency: Interim Results of a Global Phase 1 Study for Adult and Pediatric Patients (2021) (6)
Differentiation of Tr1 cells by immature dendritic cells requires IL-10 but not CD25CD4 Treg cells Running title: Induction of Tr1 cells by immature dendritic cells (2004) (6)
IgE CONTENT OF COMMERCIAL INTRAVENOUS IgG PREPARATIONS (1984) (6)
Fetal liver transplantation in immunodeficiencies and inborn errors of metabolism. (1985) (6)
Co-Expression of FOXP3FL and FOXP3Δ2 Isoforms Is Required for Optimal Treg-Like Cell Phenotypes and Suppressive Function (2021) (5)
First Report of Non-Genotoxic Conditioning with JSP191 (anti-CD117) and Hematopoietic Stem Cell Transplantation in a Newly Diagnosed Patient with Severe Combined Immune Deficiency (2020) (5)
Genomic Loss of the Mismatched HLA Locus in Leukemia Is a Major Mechanism of in Vivo Escape from T Cell Immunosurveillance Following Haploidentical HSCT (2008) (5)
Engineered type 1 regulatory T cells designed for clinical use kill primary pediatric acute myeloid leukemia cells (2020) (5)
T cell repertoire and tolerance after fetal stem cell transplantation. (1992) (5)
Deep profiling of single T cell receptor repertoire and phenotype with targeted RNA-seq (TECH2P.927) (2015) (5)
BAT2 and BAT3 polymorphisms as novel genetic risk factors for rejection after HLA-related stem cell transplantation (2014) (5)
An anti-CD 45 RO / RB monoclonal antibody modulates T cell responses via induction of apoptosis and generation of regulatory T cells (2005) (4)
Immuno responses of cord blood cells. (1998) (4)
Systemic and cellular release of IL-10 in human BMT (1995) (4)
Epigenetic and Immunological Indicators of IPEX Disease in subjects with FOXP3 gene mutation. (2022) (4)
Sequential Stem Cell-Kidney Transplantation in Schimke Immuno-osseous Dysplasia. (2022) (4)
Antigen-specific dependence of Tr 1-cell therapy in preclinical models of islet transplantation Running title : Tr 1-cell therapy in islet transplantation (2009) (4)
Gene Therapy for Fanconi Anemia, Complementation Group a: Updated Results from Ongoing Global Clinical Studies of RP-L102 (2020) (3)
The role of cytokines in transplantation tolerance (1995) (3)
Cloning of a novel cell type from human fetal liver expressing cytoplasmic CD3 delta and epsilon but not membrane CD3. (1991) (3)
JSP191 As a Single-Agent Conditioning Regimen Results in Successful Engraftment, Donor Myeloid Chimerism, and Production of Donor Derived Naïve Lymphocytes in Patients with Severe Combined Immunodeficiency (SCID) (2021) (3)
Transplantation of mismatched human fetal liver cells: tolerance induction via clonal deletion and clonal anergy. (1995) (3)
Correction of autoimmune IL2RA mutations in primary human T cells using non-viral genome targeting (2017) (3)
The role of tissue adaptation and graft size in immune tolerance. (2007) (3)
BHLHE40 Regulates IL-10 and IFN-γ Production in T Cells but Does Not Interfere With Human Type 1 Regulatory T Cell Differentiation (2021) (3)
Clonal Analyses of Retroviral Vector Integrations in ADA-SCID Patients Treated with Stem Cell Gene Therapy. (2006) (3)
Reprogramming human T cell function and specificity with non-viral genome targeting (2018) (3)
Pillars Article: The X-Linked Lymphoproliferative Disease Gene Product SAP Regulates Signals Induced through the Co-Receptor SLAM. Nature. 1998. 395: 462-469. (2017) (3)
The Effect of Ethnicity in the Rate of Beta Cell Functional Loss in the First 3 Years After Type 1 Diabetes Diagnosis. (2020) (2)
In vivo neutralization of inflammatory cytokines might not be necessary for regulatory T-cell immunotherapy (2007) (2)
Low MW B-cell growth factor potentiates histamine release from human basophil leucocytes. (1991) (2)
In-Vivo Expansion of T Regulatory Cells by Rapamycin in a Calcineurin-Inhibitor Free GVHD Prophylaxis in Unmanipulated Haploidentical Stem Cell Transplantation (SCT) (2011) (2)
Thymic Selection of the Human T Cell Receptor Vfl Repertoire in SC1D-hu Mice (2003) (2)
Downregulation of SATB1 by miRNAs reduces megakaryocyte/erythroid progenitor expansion in preclinical models of Diamond–Blackfan anemia (2022) (2)
Αβ T-Cell/CD19 B-Cell Depleted Haploidentical Stem Cell Transplantation: A New Platform for Curing Rare and Monogenic Disorders (2020) (2)
Loss of FOXP3 function causes expansion of two pools of autoreactive T cells in patients with IPEX syndrome (2022) (2)
Regulatory Type 1 T Cell Infusion in Mismatched Related or Unrelated Hematopoietic Stem Cell Transplantation (HSCT) for Hematologic Malignancies (2019) (2)
Pre-clinical development and molecular characterization of an engineered type 1 regulatory T-cell product suitable for immunotherapy. (2021) (2)
First Evidence That an Antibody Against CD117 Can Enable Hematopoietic Stem Cell Engraftment in Patients Undergoing Transplantation (2018) (2)
Rapamycin-Based GvHD Prophylaxis Is Effective in T-Cell Replete Unmanipulated Haploidentical Peripheral Stem Cell Transplantation for Advanced Haematological Malignancies: Results in 46 Patients. (2009) (2)
Tolerance to Alloantigens and Recognition for “Allo + X” Induced in Humans by Fetal Stem Cell Transplantation (1994) (2)
Immunological tolerance following stem cell transplantation in human fetuses in utero. (1997) (2)
Optimal Thalassemia Free Survival and Minimal Regimen Related Toxicity in 50 Consecutive Transplants of High Risk Beta Thalassemia Pediatric Patients Using Myelablative Therapy with Intravenous Busulphan. (2008) (2)
IPEX Syndrome: Clinical Profile, Biological Features, and Current Treatment (2011) (2)
Comment on M. Guillot‐Delost et al. (2008;10:834‐846): Clinical‐grade preparation of human natural regulatory T cells encoding the thymidine kinase suicide gene as a safety gene (2009) (1)
Corrigendum to "Evidence for Long-term Efficacy and Safety of Gene Therapy for Wiskott-Aldrich Syndrome in Preclinical Models". (2009) (1)
Evidence for Efficacy and Safety of Lentiviral Mediated Gene Transfer in T Cells and CD34+ Cells from Wiskott-Aldrich Syndrome Patients. (2006) (1)
631. Modulation of Immune Response to Gene Therapy Derived Products by CD4+ CD25+ T Regulatory Cells (2004) (1)
Patients Inhibit Pathogenic T Cells from the Intestinal Mucosa of Treated Celiac Gliadin-Specific Type 1 Regulatory T Cells (2006) (1)
OR.40. Foxp3 Mutations in Children: Different Degrees of Impairment in Regulatory and Effector T-Cell Functions in Patients with Distinct Genotypes and Phenotypes (2006) (1)
Gene editing using CRISPR enables FOXP3 gene repair in HSPCs and IPEX patient T cells (2020) (1)
dependent ILT4/HLA-G pathway - requires the IL-10 Differentiation of type 1 T regulatory cells (Tr1) by tolerogenic DC-10 (2012) (1)
123. Gene Editing as a Therapeutic Approach to Treat IPEX Syndrome (2016) (1)
BAT2 and BAT3 polymorphisms as novel genetic risk factors for rejection after HLA-related SCT (2014) (1)
Long-term efficacy and safety of hematopoietic stem cell gene therapy mediated by lentiviral vectors in the murine model of Wiskott-Aldrich syndrome (2008) (1)
Immunoregulatory cell therapy with lentiviral-mediated FOXP3 converted CD4+ T cells into Treg cells: towards the proof-of-concept application in IPEX syndrome (2019) (1)
Type 1 regulatory T cell-mediated tolerance in health and disease (2022) (1)
Lentiviral-mediated Gene Therapy for Adults and Children with Severe Pyruvate Kinase Deficiency: Results from an Ongoing Global Phase 1 Study (2022) (1)
Corrigendum: Coexpression of CD49b and LAG-3 identifies human and mouse T regulatory type 1 cells (2014) (1)
Integration-defective lentiviral vectors for hemophilia: a safer platform for immune tolerance inducation and reduced genotoxicity (2010) (1)
Erratum: Preclinical Safety and Efficacy of Human CD34+ Cells Transduced with Lentiviral Vector for the Treatment of Wiskott-Aldrich Syndrome (Molecular Therapy (2013) 21 (175-184) DOI:10.1038/mt.2012.23) (2016) (1)
Cell therapy with human T regulatory type 1 cells in allogeneic transplantations (2011) (1)
Induction of CD 4 1 T Cell Alloantigen-Specific Hyporesponsiveness by IL-10 and TGF-b 1 (1999) (1)
Effects of Cytokine Administration on Human Hematopoiesis in SCID-hu Mice (1995) (1)
Human T-cell development in SCID-hu mice (1995) (1)
In Vitro Induction of Peanut-Specific Tr1 Cells (2016) (1)
Changing the Natural History of Fanconi Anemia Complementation Group-A with Gene Therapy: Early Results of U.S. Phase I Study of Lentiviral-Mediated Ex-VivoFANCA Gene Insertion in Human Stem and Progenitor Cells (2019) (1)
P0006 PP GLIADIN-SPECIFIC, TYPE 1 REGULATORY T CELLS (TR1) ARE PRESENT IN THE INTESTINAL MUCOSA OF TREATED COELIAC PATIENTS (2004) (1)
Temporal, Quantitative and Functional Characteristics of Single-KIR Positive Alloreactive NK Cell Recovery Account for Impaired Graft Versus Leukemia Activity after Haploidentical HSCT. (2007) (1)
Lentiviral-Mediated Gene Therapy for Patients with Fanconi Anemia [Group A]: Updated Results from Global RP-L102 Clinical Trials (2022) (0)
Antigen-Presenting Cells Immunoregulatory Role of IL-10 Secreted by A Transgenic Model to Analyze the (1999) (0)
The Wiskott-Aldrich Syndrome protein (WASp) controls iNKT cell effector function. (50.39) (2010) (0)
Biffi Metachromatic Leukodystrophy Lentiviral Hematopoietic Stem Cell Gene Therapy Benefits (2013) (0)
BAT 2 and BAT 3 polymorphisms as novel genetic risk factors for rejection after HLA-related stem cell transplantation (2014) (0)
Aryl Hydrocarbon Receptor Activation in Dendritic Cells by the Small Molecular Weight Compound (VAF347) Promotes FoxP3-expressing T Cell Differentiation (2010) (0)
173. Insulin B9-23 LV-Driven Expression in Hepatocytes Combined With Suboptimal Dose of Anti-CD3 mAb Cures Type 1 Diabetes in NOD Mice (2015) (0)
Hematopoietic and Immunological Assessment in Fanconi Anemia after Ex Vivo Lentiviral FANCA Gene Therapy with RP-L102 (2022) (0)
Functional Correction of Lymphocytes and Dendritic Cells of Patients with WAS or XLT, Using Lentiviral Vectors Targeting the Expression of WAS Protein to Hematopoietic Cells. (2005) (0)
173. Insulin B9-23 LV-Driven Expression in Hepatocytes Combined With Suboptimal Dose of Anti-CD3 mAb Cures Type 1 Diabetes in NOD Mice (2015) (0)
Phase 1/1b Study of T-allo10 Infusion after HLA-Partially Matched αβ depleted-HSCT in Children and Young Adults with Hematologic Malignancies: Preliminary Results (2022) (0)
Sequential hematopoietic stem cell and kidney transplantation in schimke immuno-osseous dysplasia: towards a model for establishing functional immune tolerance for solid organ transplantation (2021) (0)
IMMUNOBIOLOGY Fatal autoimmunity in mice reconstituted with human hematopoietic stem cells encoding defective FOXP 3 (2015) (0)
Non-Toxic Single Agent Transplant Conditioning with JSP191 (an Anti-CD117 monoclonal antibody) in Infants with Newly Diagnosed Severe Combined Immune Deficiency (2021) (0)
Immunofluorescence , Flow Cytometry , and Cell Sorting (2003) (0)
Longitudinal assessment of health-related quality of life and healthcare satisfaction after haematopoietic stem cell transplantation in children with thalassaemia (2010) (0)
The Wiskott-Aldrich Syndrome protein (WASp) controls iNKT cell effector function. (2010) (0)
Reply to Comment on “Stability of human rapamycin-expanded CD4+CD25+ T-regulatory cells” Haematologica 2011;96(9):1357–65 (2012) (0)
Role of IL-10 in Transplantation Tolerance (1994) (0)
The Women of FOCIS: Promoting Equality and Inclusiveness in a Professional Federation of Clinical Immunology Societies (2022) (0)
cells SAP controls the cytolytic activity of CD8+ T cells against EBV-infected (2013) (0)
Erratum to "Lentiviral Vector-Mediated Gene Transfer in T Cells from Wiskott-Aldrich Syndrome Patients Leads to Functional Correction". (2005) (0)
Author's response to reviews Title: Health related quality of life in Middle-Eastern children with beta- thalassemia Authors: (2012) (0)
Epitope-Specific Typing (EST) for HLA-DPB1 Matching: Proof of Principle for an Innovative Approach to Unrelated Hematopoietic Stem Cell Donor Selection. (2006) (0)
Stromal-cell-independent proliferation of human bone marrow CD34+CD19+ pro-B cells in vitro (1994) (0)
Thymic hormones II (1985) (0)
Engineering Human Invariant Natural Killer T (iNKT) Cells to Overexpress Immunomodulatory Cytokines (2021) (0)
Title: Loss of FOXP3 function causes expansion of two pools of autoreactive 1 T cells in patients with IPEX syndrome. (2022) (0)
Liver Gene Therapy by Lentiviral Vectors Allows Partial Correction of Two Hemophilia B Dogs and Revert Pre-Existing Anti-Transgene Immunity in Mice (2012) (0)
myeloid-cell development fetal liver and thymus: CD7 expression in the early stages of T- and Phenotypic and functional analysis of T-cell precursors in the human (2011) (0)
metabolic defects deaminase (ADA)-deficient mice and corrects their immune and Ex vivo gene therapy with lentiviral vectors rescues adenosine (2012) (0)
Induction of CD4+ regulatory T cells by soluble HLA-G isoforms. (2012) (0)
TCRaβ+ T-Cell/CD19+ B-Cell Depleted Haploidentical Stem Cell Transplantation for Fanconi Anemia: The Stanford Children’s Experience (2023) (0)
Sam Gambhir on progress in precision health 5 questions (2018) (0)
Efficient Generation of Donor-Specific Tr1 Cells from Patients on Hemodialysis: 1965 (2012) (0)
[Biomedical research: a need or a luxury?]. (2008) (0)
Lentiviral-Mediated Gene Therapy for Severe Pyruvate Kinase Deficiency: Results from an Ongoing Global Phase 1 Study (2023) (0)
Chimerism Following Fetal Liver and Thymus Transplantation (1984) (0)
79. Systemic Administration of Lentiviral Vectors Triggers Innate Host Responses (2006) (0)
Contents Vol. 129, 2002 (2002) (0)
Abstracts of the third international conference on immunopharmacologyThymic hormones II: Congenital acquired immunodeficiency syndrome treated with thymostimulin (1985) (0)
906. Successful functional correction of T cells from Wiskott-Aldrich syndrome patients with lentiviral vectors (2004) (0)
Current understanding of the Wiskott–Aldrich syndrome and prospects for gene therapy (2007) (0)
331. Lentivirus-Mediated Ex Vivo Gene Therapy in ADA-Deficient SCID Mice (2005) (0)
University of Groningen In Vivo Tracking of Human Hematopoiesis Reveals Patterns of Clonal Dynamics during Early and Steady-State Reconstitution Phases Biasco, (0)
51. LV. InsB9-23/Anti-CD3 mAb Inhibits Recurrence of Autoimmunity in NOD Mice After Islet Transplants (2016) (0)
Gene Therapy for Fanconi Anemia [Group A]: Interim Results of RP-L102 Clinical Trials (2021) (0)
IPEX-like syndrome: a quantitative defect of regulatory T cells detected by demethylation analysis of the Foxp3 locus (2012) (0)
468. Cellular Therapy with Transgene Expressing APC Activates CD4+CD25+ Regulatory T Cells Which Modulate the Immune Response to Gene Therapy Derived Products in Immunocompetent Mice (2005) (0)
SATB1 chromatin loops regulate Megakaryocyte/Erythroid Progenitor Expansion by facilitating HSP70 and GATA1 induction. (2023) (0)
Parent-Child Perceptions of Health-Related Quality of Life in Pediatric Patients with Beta-Thalassemia (2012) (0)
637. Targeting of Myeloid Leukemia by IL-10-Engineered Human CD4+ Tr1 Cells (2016) (0)
Celebrating 20 years of FOCIS (2020) (0)
Hematopoietic stem cell gene therapy for ADA-SCID (2008) (0)
Author Correction: Gene correction for SCID-X1 in long-term hematopoietic stem cells (2019) (0)
Efficient gene transfer into primitive hematopoietic progenitors using a bone marrow microenvironment cell line engineered to produce retroviral vectors. (2004) (0)
Immune deficiencies , infection , and systemic immune disorders B-cell reconstitution after lentiviral vector – mediated gene therapy in patients with Wiskott-Aldrich syndrome (0)
Gene correction for SCID-X1 in long-term hematopoietic stem cells (2019) (0)
The Pancreatic Lymph-nodes of Type 1 Diabetic Patients Contain Epigenetically-imprinted Natural Regulatory T Cells which Lack Suppressive Function (2010) (0)
36. Improved Lentiviral Vectors for Systemic Gene Transfer in the Absence of an Immune Response (2005) (0)
Initial Results from Stanford Children’s Fanconi Anemia Clinical Trial Using JSP191 Antibody Conditioning and TCRαβ+ T-Cell/CD19+ B-Cell Depleted Grafts (2023) (0)
Study of peripheral tolerance in ADA SCID patients after different treatments (143.36) (2010) (0)
Coexpression of CD163 and CD141 identifies human circulating IL-10-producing dendritic cells (DC-10) (2019) (0)
MICROSATELLITES: IN HLA REGION DEVELOPMENT OF INTERFACE AT NCBI’S DBMHC Session Transplantation HEART TRANSPLANTS PERSISTENT MIXED CHIMERISM IN EX-THALASSEMIC PATIENTS AFTER BMT (2005) (0)
9. Hematopoietic stem cell based gene therapy for the treatment of metachromatic leukodystrophy: Towards clinical testing (2008) (0)
CD4+CD25+ regulatory T cells vivo by transgene-expressing antigen-presenting cells but not by The immune response to lentiviral-delivered transgene is modulated in (2013) (0)
Health-related quality of life in pediatric patients with beta-thalassemia according to child and parent reports (2011) (0)
Type 1 regulatory T (Tr1) cells: from the bench to the bedside (2012) (0)
Erratum: Cell therapy with human T regulatory type 1 cells in allogeneic transplantations (Immunotherapy (2011) 3:4 (27)) (2011) (0)
fetal pro-B cells in vitro stromal- cell-independent expansion and differentiation of human The FLK2/FLT3 ligand synergizes with interleukin-7 in promoting (2011) (0)
Long-Term Treatment Outcome in IPEX Syndrome Patients: An International Multicenter Retrospective Study (2018) (0)
Wiskott-Aldrich Syndrome Patients T Cells from + and CD8 + in CD4 Defective Th1 Cytokine Gene Transcription (2006) (0)
Clonal tracking of engineered human hematopoiesis through integration sites analysis (2016) (0)
Impaired GvL Potential of Natural Killer Cells Early Reconstituting Following Haploidentical HSCT. (2006) (0)
Title Minimum Information about T Regulatory Cells : A Step toward Reproducibility and Standardization Permalink (2018) (0)
Early Epigenetic Immune Quantification Following Alpha/Beta T-Cell/CD19 B-Cell Depleted Haploidentical Stem Cell Transplant Correlates with CD4+ T Cell Recovery at Day +100 (2020) (0)
Long-Term Safety and Efficacy of Stem Cell Gene Therapy for ADA-SCID. (2006) (0)
Regulatory T Cells in the Coeliac Intestinal Mucosa (2008) (0)
Breaking Bad in the Immune System: Loss of Tolerance (2015) (0)
Corrigendum to "Preclinical Safety and Efficacy of Human CD34+ Cells Transduced With Lentiviral Vector for the Treatment of Wiskott-Aldrich Syndrome". (2016) (0)
Chimerism Analysis in Pediatric Hematopoietic Stem Cell Transplantation for Non-Malignant Disorders (2019) (0)
Human Type 1 T Regulatory Cells and IL-10 Induce the Differentiation of α IFN - (2001) (0)
T-allo10 Infusion after αβ depleted-HSCT in Children and Young Adults with Hematologic Malignancies: Improved Immune Reconstitution in the Absence of Severe GvHD (2023) (0)
IL-4 induced IgE synthesis and IL-4 production in newborns (1990) (0)
Multi-omics analysis reveals a crucial role for Retinoic Acid in promoting epigenetic and transcriptional competence of an in vitro model of human Pharyngeal Endoderm (2022) (0)
A research institute at a turning point. Interview by Kathryn Claiborn. (2012) (0)
treated alloreactive T cells that do not induce graft-versus-host disease - β cycle progression in interleukin 10 and transforming growth factor- Altered T-cell receptor?+?CD28-mediated signaling and blocked cell (2013) (0)
Human Type 1 T Regulatory Cells (2008) (0)
CD4+ T Regulatory Cells and Modulation of Undesired Immune Responses (2019) (0)
A New Combined Therapy (anti-CD45RB mAb + rapamycin + IL-10) Able to Induce Active Long-term Tolerance in a Stringent Pre-clinical Model of Allogeneic Islet Transplantation (2008) (0)
345. Gene Therapy for Wiskott-Aldrich Syndrome Using Lentiviral Vectors: Evidence for Efficacy and Safety after Transduction of Human T Cells and Hematopoietic Stem Cells (2005) (0)
Liver gene therapy by lentiviral vectors provides stable clinical benefit in three hemophilia B dogs and eradicates factor IX inhibitors in mice (2013) (0)
65. Long-Term Effects of Hematopoietic Stem Cell Gene Therapy in the Murine Model of Wiskott-Aldrich Syndrome: Persistence of Functional Correction of T Cells and Lack of Malignant Trasformation (2006) (0)
Su.98. Defining a Role for FOXP3 in Human Cd4+ T-Cells (2006) (0)
Molecular and functional heterogeneity of IL-10-producing CD4+ T cells (2018) (0)
[Gene therapy in pediatrics]. (2009) (0)
Functional Immune Tolerance Induced By Sequential Hematopoietic Stem Cell-Solid Organ Transplantation (2021) (0)
1335 Human (cid:2) (cid:2) T Suppressor Cell Clones Produce Transforming Growth Factor (cid:3) , but not Interleukin 10, and Are Distinct from Type 1 T Regulatory (2002) (0)
Brief Report Mobilized Blood CD34 1 Cells Transduced and Selected with a Clinically Applicable Protocol Reconstitute Lymphopoiesis in SCID-Hu Mice (2004) (0)
672. Lentiviral Vectors Targeting WASp Expression to Hematopoietic Cells, Efficiently Transduce CD34+ Cells and Correct Functions of Lymphocytes and Dendritic Cells from Wiskott- Aldrich Syndrome Patients (2006) (0)
1004. Integration Analyses in ADA-Deficient SCID Patients Successfully Treated with Stem Cell Gene Therapy (2004) (0)
Evidence for efficacy and safety of lentiviral mediated gene transfer in Wiskott–Aldrich syndrome (2008) (0)
Treg therapy and plasticity (SY6-3) Chairpersons: Shohei Hori, Maria-Grazia Roncarolo (2010) (0)
330. Lentiviral Vector Mediated Hematopoietic Stem Cell Gene Therapy Combined with Non-Lethal Conditioning Restores T Cell Function in the Murine Model of Wiskott-Aldrich Syndrome (2005) (0)
Erratum: BAT2 and BAT3 polymorphisms as novel genetic risk factors for rejection after HLA-related SCT (Bone Marrow Transplantation (2014) 49 (1452) DOI:10.1038/bmt.2014.241) (2014) (0)
Deoxyadenosine Inhibits T-Cell Activation in ADA-SCID Patients through a cAMP/PKA-Dependent Pathway. (2006) (0)
F.75. Molecular and Functional Studies in T Cells from Healthy Carriers of FOXP3 Mutations (2008) (0)
146 Alloantigen-specific Tr1 cells designed to prevent GvHD have a distinct molecular identity and suppress through CTLA-4 and PD-1 (2020) (0)
In search of T-cell progenitors in the human foetal liver. (1994) (0)
Ectopic FOXP3 Expression Preserves Primitive Features Of Human Hematopoietic Stem Cells While Impairing Functional T Cell Differentiation (2017) (0)
perforin gene A proportion of patients with lymphoma may harbor mutations of the (2013) (0)
Characterization of B cell function in Wiskott Aldrich Syndrome (143.37) (2010) (0)
Subject Index Vol. 129, 2002 (2002) (0)
Hergen Spits—A legend at the top of his career (2021) (0)
Engineered Type-1 Regulatory T Cells as Cellular Therapy for Treatment of Immune Mediated Diseases (2020) (0)
981. Prevention of Transgene Expression in Antigen Presenting Cells Correlate with Modulated Immune Response after In Vivo Gene Transfer (2006) (0)

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