Maria Jasin
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Biology
Maria Jasin's Degrees
- PhD Molecular Biology University of California, Berkeley
- Masters Biochemistry Stanford University
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(Suggest an Edit or Addition)Maria Jasin's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- XRCC3 promotes homology-directed repair of DNA damage in mammalian cells. (1999) (1308)
- Brca1 controls homology-directed DNA repair. (1999) (1237)
- BRCA2 is required for homology-directed repair of chromosomal breaks. (2001) (991)
- Double-Strand Break Repair-Independent Role for BRCA2 in Blocking Stalled Replication Fork Degradation by MRE11 (2011) (874)
- Recombinational DNA double-strand breaks in mice precede synapsis (2001) (856)
- Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis (2010) (837)
- Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2. (2006) (822)
- A distinct replication fork protection pathway connects Fanconi anemia tumor suppressors to RAD51-BRCA1/2. (2012) (755)
- Introduction of double-strand breaks into the genome of mouse cells by expression of a rare-cutting endonuclease. (1994) (746)
- Repair of strand breaks by homologous recombination. (2013) (712)
- Chromosome synapsis defects and sexually dimorphic meiotic progression in mice lacking Spo11. (2000) (655)
- Homology-directed repair is a major double-strand break repair pathway in mammalian cells. (1998) (647)
- Sister chromatid gene conversion is a prominent double‐strand break repair pathway in mammalian cells (2000) (598)
- Homologous recombination and human health: the roles of BRCA1, BRCA2, and associated proteins. (2015) (588)
- Expression of a site-specific endonuclease stimulates homologous recombination in mammalian cells. (1994) (544)
- Ku DNA end-binding protein modulates homologous repair of double-strand breaks in mammalian cells. (2001) (523)
- Frequent chromosomal translocations induced by DNA double-strand breaks (2000) (518)
- Positional stability of single double-strand breaks in mammalian cells (2007) (517)
- Loss of ATRX, Genome Instability, and an Altered DNA Damage Response Are Hallmarks of the Alternative Lengthening of Telomeres Pathway (2012) (492)
- A Hierarchical Combination of Factors Shapes the Genome-wide Topography of Yeast Meiotic Recombination Initiation (2011) (482)
- Genetic Steps of Mammalian Homologous Repair with Distinct Mutagenic Consequences (2004) (466)
- CDK-dependent phosphorylation of BRCA2 as a regulatory mechanism for recombinational repair (2005) (464)
- Double-strand break repair by interchromosomal recombination: suppression of chromosomal translocations. (1998) (426)
- Homology-directed dna repair, mitomycin-c resistance, and chromosome stability is restored with correction of a Brca1 mutation. (2001) (413)
- Enhancers and eukaryotic gene transcription (1985) (411)
- Genetic manipulation of genomes with rare-cutting endonucleases. (1996) (388)
- Human Fanconi anemia monoubiquitination pathway promotes homologous DNA repair. (2005) (381)
- Homologous repair of DNA damage and tumorigenesis:the BRCA connection (2002) (379)
- Androgen receptor signaling regulates DNA repair in prostate cancers. (2013) (376)
- A forward chemical genetic screen reveals an inhibitor of the Mre11-Rad50-Nbs1 complex. (2008) (371)
- Mouse HORMAD1 and HORMAD2, Two Conserved Meiotic Chromosomal Proteins, Are Depleted from Synapsed Chromosome Axes with the Help of TRIP13 AAA-ATPase (2009) (345)
- Collaboration and competition between DNA double‐strand break repair pathways (2010) (337)
- Mammalian XRCC2 promotes the repair of DNA double-strand breaks by homologous recombination (1999) (325)
- Hypoxia-induced down-regulation of BRCA1 expression by E2Fs. (2005) (315)
- Alternative end-joining is suppressed by the canonical NHEJ component Xrcc4/ligase IV during chromosomal translocation formation (2010) (310)
- RECQL5/Recql5 helicase regulates homologous recombination and suppresses tumor formation via disruption of Rad51 presynaptic filaments. (2007) (307)
- Gene Conversion Tracts from Double-Strand Break Repair in Mammalian Cells (1998) (305)
- Double-strand-break-induced homologous recombination in mammalian cells. (2001) (295)
- DNA Ligase III Promotes Alternative Nonhomologous End-Joining during Chromosomal Translocation Formation (2011) (284)
- Chromosomal translocations in human cells are generated by canonical nonhomologous end-joining. (2014) (276)
- An essential role for CtIP in chromosomal translocation formation through an alternative end-joining pathway (2011) (263)
- Double-strand breaks and tumorigenesis. (2001) (260)
- Secondary Somatic Mutations Restoring RAD51C and RAD51D Associated with Acquired Resistance to the PARP Inhibitor Rucaparib in High-Grade Ovarian Carcinoma. (2017) (248)
- Ablation of PARP-1 does not interfere with the repair of DNA double-strand breaks, but compromises the reactivation of stalled replication forks (2004) (248)
- Coupled Homologous and Nonhomologous Repair of a Double-Strand Break Preserves Genomic Integrity in Mammalian Cells (2000) (248)
- BRCA1 Tumor Suppression Depends on BRCT Phosphoprotein Binding, But Not Its E3 Ligase Activity (2011) (244)
- Rad51 overexpression promotes alternative double-strand break repair pathways and genome instability (2004) (241)
- Evidence for Replicative Repair of DNA Double-Strand Breaks Leading to Oncogenic Translocation and Gene Amplification (2002) (235)
- ATM controls meiotic double-strand break formation (2011) (227)
- Double-strand breaks at the target locus stimulate gene targeting in embryonic stem cells. (1995) (227)
- Distinct DNA-damage-dependent and -independent responses drive the loss of oocytes in recombination-defective mouse mutants. (2005) (218)
- Homeostatic control of recombination is implemented progressively in mouse meiosis (2012) (217)
- Interplay between human DNA repair proteins at a unique double‐strand break in vivo (2006) (217)
- Distinct Properties of the XY Pseudoautosomal Region Crucial for Male Meiosis (2011) (211)
- Crucial roles for DNA ligase III in mitochondria but not in XRCC1-dependent repair (2011) (206)
- A long and complex enhancer activates transcription of the gene coding for the highly abundant immediate early mRNA in murine cytomegalovirus. (1985) (202)
- Chromosomal translocations induced at specified loci in human stem cells (2009) (200)
- Meiotic homologue alignment and its quality surveillance are controlled by mouse HORMAD1 (2011) (199)
- Involvement of Mammalian Mus81 in Genome Integrity and Tumor Suppression (2004) (199)
- Surveillance of Different Recombination Defects in Mouse Spermatocytes Yields Distinct Responses despite Elimination at an Identical Developmental Stage (2005) (198)
- The Landscape of Mouse Meiotic Double-Strand Break Formation, Processing, and Repair (2016) (195)
- Analysis of Gene Targeting and Intrachromosomal Homologous Recombination Stimulated by Genomic Double-Strand Breaks in Mouse Embryonic Stem Cells (1998) (190)
- Ku80-deficient Cells Exhibit Excess Degradation of Extrachromosomal DNA* (1996) (189)
- Mouse RAD54 Affects DNA Double-Strand Break Repair and Sister Chromatid Exchange (2000) (188)
- Chromosomal double-strand break repair in Ku80-deficient cells. (1996) (188)
- Homology-Directed Repair and the Role of BRCA1, BRCA2, and Related Proteins in Genome Integrity and Cancer. (2018) (187)
- Loss of heterozygosity induced by a chromosomal double-strand break. (1997) (185)
- Chromosomal translocation mechanisms at intronic alu elements in mammalian cells. (2005) (182)
- Transmeiotic differentiation of male germ cells in culture (1993) (173)
- Mouse TRIP13/PCH2 Is Required for Recombination and Normal Higher-Order Chromosome Structure during Meiosis (2010) (169)
- Repair of Double-Strand Breaks by Homologous Recombination in Mismatch Repair-Defective Mammalian Cells (2001) (168)
- Palindrome resolution and recombination in the mammalian germ line (1997) (167)
- The democratization of gene editing: Insights from site-specific cleavage and double-strand break repair. (2016) (165)
- Formation of NHEJ-derived reciprocal chromosomal translocations does not require Ku70 (2007) (164)
- Modeling oncogenic translocations: distinct roles for double-strand break repair pathways in translocation formation in mammalian cells. (2006) (163)
- Cycloheximide resistance in yeast: the gene and its protein. (1983) (160)
- Genetic Analysis of the DNA-dependent Protein Kinase Reveals an Inhibitory Role of Ku in Late S–G2 Phase DNA Double-strand Break Repair* (2001) (158)
- Assaying double-strand break repair pathway choice in mammalian cells using a targeted endonuclease or the RAG recombinase. (2006) (157)
- Collaboration of homologous recombination and nonhomologous end-joining factors for the survival and integrity of mice and cells. (2004) (156)
- Numerical constraints and feedback control of double-strand breaks in mouse meiosis. (2013) (152)
- Cancer translocations in human cells induced by zinc finger and TALE nucleases (2013) (150)
- Double-Strand Break Repair-Independent Role for BRCA2 in Blocking Stalled Replication Fork Degradation by MRE11 (2011) (149)
- ATP Hydrolysis by Mammalian RAD51 Has a Key Role during Homology-directed DNA Repair* (2002) (144)
- Deletion of an essential gene in Escherichia coli by site-specific recombination with linear DNA fragments (1984) (144)
- Homologous integration in mammalian cells without target gene selection. (1988) (143)
- E3 ligase activity of BRCA1 is not essential for mammalian cell viability or homology-directed repair of double-strand DNA breaks (2008) (142)
- Modular arrangement of functional domains along the sequence of an aminoacyl tRNA synthetase (1983) (140)
- Eme1 is involved in DNA damage processing and maintenance of genomic stability in mammalian cells (2003) (139)
- An xrcc4 defect or Wortmannin stimulates homologous recombination specifically induced by double-strand breaks in mammalian cells. (2002) (138)
- Allele-Specific Chromosome Removal after Cas9 Cleavage in Human Embryos (2020) (138)
- Human Genome and Diseases:¶Double-strand breaks and translocations in cancer (2002) (124)
- Extensive Loss of Heterozygosity Is Suppressed during Homologous Repair of Chromosomal Breaks (2003) (120)
- Variant XRCC3 implicated in cancer is functional in homology-directed repair of double-strand breaks (2002) (120)
- Meiotic DNA break formation requires the unsynapsed chromosome axis-binding protein IHO1 (CCDC36) in mice (2016) (112)
- A mouse homolog of the Saccharomyces cerevisiae meiotic recombination DNA transesterase Spo11p. (1999) (110)
- BARD1 Participates with BRCA1 in Homology-Directed Repair of Chromosome Breaks (2003) (109)
- BRCA2 suppresses replication stress-induced mitotic and G1 abnormalities through homologous recombination (2017) (105)
- Chromosome healing in mouse embryonic stem cells. (1999) (103)
- Homologous recombination deficiency leads to profound genetic instability in cells derived from Xrcc2-knockout mice. (2003) (103)
- ATM Promotes the Obligate XY Crossover and both Crossover Control and Chromosome Axis Integrity on Autosomes (2008) (102)
- Mouse tetrad analysis provides insights into recombination mechanisms and hotspot evolutionary dynamics (2014) (100)
- A model of oncogenic rearrangements: differences between chromosomal translocation mechanisms and simple double-strand break repair. (2006) (98)
- Suppression of the DNA repair defects of BRCA2-deficient cells with heterologous protein fusions. (2006) (97)
- Double-strand breaks and translocations in cancer. (2002) (94)
- Comprehensive, fine-scale dissection of homologous recombination outcomes at a hot spot in mouse meiosis. (2010) (94)
- Evolutionary conservation of meiotic DSB proteins: more than just Spo11. (2010) (93)
- Inter-homologue repair in fertilized human eggs? (2017) (92)
- Chromosome Breaks and Genomic Instability (2000) (91)
- Genomic Complexity Profiling Reveals That HORMAD1 Overexpression Contributes to Homologous Recombination Deficiency in Triple-Negative Breast Cancers. (2015) (91)
- Double-strand break repair by homologous recombination in primary mouse somatic cells requires BRCA1 but not the ATM kinase (2013) (90)
- High frequency of homologous recombination in mammalian cells between endogenous and introduced SV40 genomes (1985) (86)
- Plasticity of BRCA2 Function in Homologous Recombination: Genetic Interactions of the PALB2 and DNA Binding Domains (2011) (82)
- Reduced Proficiency in Homologous Recombination Underlies the High Sensitivity of Embryonal Carcinoma Testicular Germ Cell Tumors to Cisplatin and Poly (ADP-Ribose) Polymerase Inhibition (2012) (78)
- The ATM Signaling Cascade Promotes Recombination-Dependent Pachytene Arrest in Mouse Spermatocytes (2015) (77)
- The E3 ubiquitin ligase Cullin 4A regulates meiotic progression in mouse spermatogenesis. (2011) (76)
- Homologous recombination DNA repair genes play a critical role in reprogramming to a pluripotent state. (2013) (76)
- Targeted transgenesis. (1996) (76)
- Interhomolog recombination and loss of heterozygosity in wild-type and Bloom syndrome helicase (BLM)-deficient mammalian cells (2011) (75)
- The Fanconi anemia group A protein modulates homologous repair of DNA double-strand breaks in mammalian cells. (2005) (72)
- Development of an assay to measure mutagenic non-homologous end-joining repair activity in mammalian cells (2013) (70)
- When Genome Maintenance Goes Badly Awry. (2016) (63)
- Homologous recombination assay for interstrand cross-link repair. (2011) (62)
- Fen-1 Facilitates Homologous Recombination by Removing Divergent Sequences at DNA Break Ends (2005) (59)
- The tricky path to recombining X and Y chromosomes in meiosis (2012) (58)
- Ensuring meiotic DNA break formation in the mouse pseudoautosomal region (2019) (57)
- Male Fertility Defect Associated with Disrupted BRCA1-PALB2 Interaction in Mice* (2014) (57)
- Mechanisms of Recombination between Diverged Sequences in Wild-Type and BLM-Deficient Mouse and Human Cells (2010) (56)
- Alternative Pathways for the Repair of RAG-Induced DNA Breaks (2006) (55)
- DNA damage responses by human ELG1 in S phase are important to maintain genomic integrity (2009) (52)
- Structural Requirements for the BARD1 Tumor Suppressor in Chromosomal Stability and Homology-directed DNA Repair* (2007) (52)
- Polycomb Protein SCML2 Associates with USP7 and Counteracts Histone H2A Ubiquitination in the XY Chromatin during Male Meiosis (2015) (51)
- Distinct genetic control of homologous recombination repair of Cas9-induced double-strand breaks, nicks and paired nicks (2016) (51)
- Repeat expansion by homologous recombination in the mouse germ line at palindromic sequences (2001) (51)
- A Double-Strand Break in a Chromosomal LINE Element Can Be Repaired by Gene Conversion with Various Endogenous LINE Elements in Mouse Cells (2000) (49)
- Genomic and chromatin features shaping meiotic double-strand break formation and repair in mice (2017) (49)
- Dispensable pieces of an aminoacyl tRNA synthetase which activate the catalytic site (1984) (48)
- RECQ1 plays a distinct role in cellular response to oxidative DNA damage. (2012) (48)
- Role for the Mammalian Swi5-Sfr1 Complex in DNA Strand Break Repair through Homologous Recombination (2010) (47)
- NHEJ deficiency and disease. (2001) (46)
- p21 promotes error-free replication-coupled DNA double-strand break repair (2012) (45)
- CRISPR-Cas9–guided oncogenic chromosomal translocations with conditional fusion protein expression in human mesenchymal cells (2017) (44)
- Molecular cross-talk among chromosome fragility syndromes. (2004) (44)
- Homologous Recombination and Replication Fork Protection: BRCA2 and More! (2017) (42)
- ATM loss leads to synthetic lethality in BRCA1 BRCT mutant mice associated with exacerbated defects in homology-directed repair (2017) (41)
- 53BP1 ablation rescues genomic instability in mice expressing ‘RING‐less’ BRCA1 (2016) (41)
- Measuring recombination proficiency in mouse embryonic stem cells. (2005) (41)
- Induction of Chromosomal Translocations with CRISPR-Cas9 and Other Nucleases: Understanding the Repair Mechanisms That Give Rise to Translocations. (2018) (40)
- Mechanisms of germ line genome instability. (2016) (40)
- Local and sex-specific biases in crossover vs. noncrossover outcomes at meiotic recombination hot spots in mice (2015) (39)
- ATR is required to complete meiotic recombination in mice (2017) (39)
- Gene conversion is strongly induced in human cells by double-strand breaks and is modulated by the expression of BCL-x(L). (2002) (38)
- Preaching about the converted: how meiotic gene conversion influences genomic diversity (2012) (38)
- p53 and TAp63 participate in the recombination-dependent pachytene arrest in mouse spermatocytes (2017) (38)
- Attenuating homologous recombination stimulates an AID-induced antileukemic effect (2013) (37)
- Reduced repair of DNA double-strand breaks by homologous recombination in a DNA ligase I-deficient human cell line. (2005) (37)
- Molecular basis for enhancement of the meiotic DMC1 recombinase by RAD51 associated protein 1 (RAD51AP1) (2011) (36)
- PARP Inhibitors in Clinical Use Induce Genomic Instability in Normal Human Cells (2016) (36)
- Two mutations in the dispensable part of alanine tRNA synthetase which affect the catalytic activity. (1985) (35)
- Palindromic DNA and Genome Stability: Further Studies a (1999) (35)
- Shu complex SWS1-SWSAP1 promotes early steps in mouse meiotic recombination (2018) (34)
- Identification of Novel Radiosensitizers in a High-Throughput, Cell-Based Screen for DSB Repair Inhibitors (2014) (34)
- Mouse BAZ1A (ACF1) Is Dispensable for Double-Strand Break Repair but Is Essential for Averting Improper Gene Expression during Spermatogenesis (2013) (34)
- The transposase domain protein Metnase/SETMAR suppresses chromosomal translocations. (2010) (32)
- 53BP1 is a haploinsufficient tumor suppressor and protects cells from radiation response in glioma. (2012) (32)
- Expression of Arf Tumor Suppressor in Spermatogonia Facilitates Meiotic Progression in Male Germ Cells (2011) (32)
- DNA ligase III (2011) (31)
- Gene targeting at the human CD4 locus by epitope addition. (1990) (31)
- Amino acid replacements that compensate for a large polypeptide deletion in an enzyme. (1985) (30)
- Rad51 presynaptic filament stabilization function of the mouse Swi5–Sfr1 heterodimeric complex (2012) (30)
- BRCA 1 Tumor Suppression Depends on BRCT Phosphoprotein Binding , But Not Its E 3 Ligase Activity (2014) (29)
- Glycosylphosphatidylinositol-anchored CD4/Thy-1 chimeric molecules serve as human immunodeficiency virus receptors in human, but not mouse, cells and are modulated by gangliosides (1991) (29)
- Homology-directed Fanconi anemia pathway crosslink repair is dependent on DNA replication (2011) (29)
- Chromosomal double-strand breaks introduced in mammalian cells by expression of I-Sce I endonuclease. (1999) (29)
- Assaying break and nick-induced homologous recombination in mammalian cells using the DR-GFP reporter and Cas9 nucleases. (2014) (29)
- Mouse Strains with an Active H2-Ea Meiotic Recombination Hot Spot Exhibit Increased Levels of H2-Ea-Specific DNA Breaks in Testicular Germ Cells (2004) (28)
- Prolonged Particulate Hexavalent Chromium Exposure Suppresses Homologous Recombination Repair in Human Lung Cells. (2016) (28)
- Robust homology-directed repair within mouse mammary tissue is not specifically affected by Brca2 mutation (2016) (27)
- Analysis of Escherichia coli beta-galactosidase expression in transgenic mice by flow cytometry of sperm. (1992) (25)
- Differential Requirements for the RAD51 Paralogs in Genome Repair and Maintenance in Human Cells (2019) (25)
- Induction of chromosomal translocations in mouse and human cells using site-specific endonucleases. (2008) (25)
- Mutations that affect meiosis in male mice influence the dynamics of the mid-preleptotene and bouquet stages. (2006) (25)
- Control of meiotic double-strand-break formation by ATM: local and global views (2017) (23)
- Loss of 53BP1 is a gain for BRCA1 mutant cells. (2010) (23)
- Meiotic crossover hotspots contained in haplotype block boundaries of the mouse genome (2007) (22)
- Biallelic targeting of expressed genes in mouse embryonic stem cells using the Cas9 system. (2014) (21)
- Mechanistic insight into crossing over during mouse meiosis (2019) (20)
- Creating cancer translocations in human cells using Cas9 DSBs and nCas9 paired nicks. (2014) (19)
- Distinct effects of DNA-PKcs and Artemis inactivation on signal joint formation in vivo. (2008) (19)
- Prevention of DNA Replication Stress by CHK1 Leads to Chemoresistance Despite a DNA Repair Defect in Homologous Recombination in Breast Cancer (2020) (18)
- A model for testing recombinogenic sequences in the mouse germline. (1996) (18)
- Recombination between two chromosomes: implications for genomic integrity in mammalian cells. (2000) (18)
- Unraveling Ewing Sarcoma Tumorigenesis Originating from Patient-Derived Mesenchymal Stem Cells (2021) (17)
- Mice deficient for the type II topoisomerase‐like DNA transesterase Spo11 show normal immunoglobulin somatic hypermutation and class switching (2002) (17)
- Isolation of meiotic recombinants from mouse sperm. (2011) (17)
- RAD51B Activity and Cell Cycle Regulation in Response to DNA Damage in Breast Cancer Cell Lines (2014) (16)
- Studies on the Influence of Cytosine Methylation on DNA Recombination and End-joining in Mammalian Cells (*) (1995) (15)
- Measuring recombination proficiency in mouse embryonic stem cells. (2014) (15)
- Generation of chromosomal translocations that lead to conditional fusion protein expression using CRISPR-Cas9 and homology-directed repair. (2017) (14)
- Double-Strand Break Repair and Homologous Recombination in Mammalian Cells (2001) (14)
- How much is enough? Control of DNA double-strand break numbers in mouse meiosis (2013) (14)
- Testicular Germ Cell Tumors Acquire Cisplatin Resistance by Rebalancing the Usage of DNA Repair Pathways (2021) (13)
- EXO1 suppresses double-strand break induced homologous recombination between diverged sequences in mammalian cells. (2017) (12)
- RAD51 can inhibit PDGF-B-induced gliomagenesis and genomic instability. (2011) (12)
- Distinct pathways of homologous recombination controlled by the SWS1–SWSAP1–SPIDR complex (2020) (10)
- Homologous Recombination between Heterologs during Repair of a Double‐Strand Break: Suppression of Translocations in Normal Cells (1999) (10)
- Mouse embryonic stem cells exhibit high levels of extrachromosomal homologous recombination in a chloramphenicol acetyltransferase assay system. (1991) (10)
- Evaluation of PARP inhibition as a platinum sparing strategy in Brca2-deficient pancreatic tumors. (2014) (9)
- Distinct Requirements of CHD4 during B Cell Development and Antibody Response (2019) (9)
- De novo deletions and duplications at recombination hotspots in mouse germlines (2021) (8)
- Rapid interrogation of cancer cell of origin through CRISPR editing (2021) (8)
- RAD51D splice variants and cancer-associated mutations reveal XRCC2 interaction to be critical for homologous recombination. (2019) (8)
- Introduction of double-strand breaks into the genome of mouse cells by expression of a rare-cutting endonuclease (1994) (7)
- Seeking new meiotic genes (2003) (6)
- Inhibition of poly (ADP-ribose) polymerase-1 (PARP-1) to increase radiosensitivity of human pancreatic cancer (PAC) cell lines proficient in homology-directed repair (HDR). (2012) (6)
- Antibodies Get a Break (2007) (6)
- BRCA2: safeguarding the genome through homologous recombination (2007) (5)
- Under the Influence: Cas9 Ends and DNA Repair Outcomes. (2018) (5)
- Extrachromosomal assay for DNA double-strand break repair. (1999) (5)
- Effect of propofol on reactivity of isolated human internal mammary artery fragments (2002) (4)
- Analysis of recombinants in female mouse meiosis. (2013) (4)
- Generation of human embryonic stem cell models to exploit the EWSR1-CREB fusion promiscuity as a common pathway of transformation in human tumors (2021) (4)
- filaments suppresses tumor formation via disruption of Rad 51 presynaptic RECQL 5 / Recql 5 helicase regulates homologous recombination and Material Supplemental (2007) (3)
- p 21 promotes error-free replication-coupled DNA double-strand break repair (2012) (3)
- BRCA2 suppresses replication stress-induced mitotic and G1 abnormalities through homologous recombination (2017) (3)
- Inhibition of colorectal cancer genomic copy number alterations and chromosomal fragile site tumor suppressor FHIT and WWOX deletions by DNA mismatch repair (2017) (3)
- in Mouse Embryonic Stem Cells Stimulated by Genomic Double-Strand Breaks Recombination Intrachromosomal Homologous Analysis of Gene Targeting and (2012) (3)
- Assessing Homologous Recombination and Interstrand Cross-Link Repair in Embryonal Carcinoma Testicular Germ Cell Tumor Cell Lines. (2021) (3)
- Interhomolog Homologous Recombination in Mouse Embryonic Stem Cells. (2021) (3)
- Gene conversion is a prominent DNA repair pathway in mammalian cells (2001) (2)
- De novo deletions and duplications at recombination hotspots in mouse germlines (2020) (2)
- Chromosomal double-strand break repair in Ku 8 O-deficient cells ( xrs-6 cells / radiation sensitive mutants / I-SceI endonuclease / homologous recombination / end-joining ) (2005) (2)
- Immunology. Antibodies get a break. (2007) (2)
- Corrigendum: A forward chemical genetic screen reveals an inhibitor of the Mre11|[ndash]|Rad50|[ndash]|Nbs1 complex (2009) (2)
- Novel Role for PTEN in Regulating Non Homologous End‐Joining Factor 53BP1 to Suppress Replication Fork Instability (LB120) (2014) (2)
- Inhibition of colorectal cancer genomic copy number alterations and chromosomal fragile site tumor suppressor FHIT and WWOX deletions by DNA mismatch repair. (2017) (2)
- Accolades for the DNA Damage Response. (2015) (2)
- 53BP1 nuclear body-marked replication stress in a human mammary cell model of BRCA2 deficiency (2018) (1)
- Homologous recombination–deficient mutation cluster in tumor suppressor RAD51C identified by comprehensive analysis of cancer variants (2022) (1)
- Gene Editing 20 Years Later (2016) (1)
- Homology-Directed Repair Is Diminished in PTEN-Positive Breast Tumor Cells. (2009) (1)
- Abstract A27: Assessing somatic tumor-associated RAD51 mutations and screening for novel dominant-interfering RAD51 proteins (2017) (1)
- XRCC3 loss leads to midgestational embryonic lethality in mice. (2021) (1)
- In vivo inactivation of RAD51-mediated homologous recombination leads to premature aging, but not to tumorigenesis (2022) (1)
- Long-term survival of an ovarian cancer patient harboring a RAD51C missense mutation (2021) (1)
- Homologous Recombination Independent Role For BRCA2 In Blocking Stalled Replication Fork Degradation By MRE11 (2011) (1)
- Shu complex SWS1-SWSAP1 promotes early steps in mouse meiotic recombination (2018) (1)
- Abstract A08: A novel system determines the functional significance of ovarian tumor mutations in the homologous recombination gene RAD51C (2018) (1)
- UvA-DARE ( Digital Academic Repository ) Mouse TRIP 13 / PCH 2 Is Required for Recombination and Normal Higher-Order Chromosome Structure during (2010) (1)
- Size polymorphism and the structure of aminoacyl-tRNA synthetases. (1984) (1)
- Eukaryotic Recombination: Initiation by Double‐Strand Breaks (2020) (1)
- Introduction ofDouble-Strand Breaks intotheGenomeof MouseCells byExpression ofa Rare-Cutting Endonuclease (1994) (0)
- Abstract A10: The impact of cancer-associated RAD51C mutations in homologous recombination (2017) (0)
- Abstract PD09-10: DNA Damage and Repair in Mammary Gland Development (2012) (0)
- The tricky path to recombining sex chromosomes in meiosis (2012) (0)
- Ensuring meiotic DNA break formation in the mouse pseudoautosomal region (2020) (0)
- Phenotypes of cells deficient in components of the two major pathways for DSB repaira (2001) (0)
- Role of the breast cancer suppressor BRCA1 in the maintenance of genomic integrity (97.3) (2014) (0)
- Recombination in Mammalian Systems (2004) (0)
- Abstract B37: PARP inhibitor olaparib induces genomic instability in normal mammalian cells (2017) (0)
- Molecular Basis for Enhancement of the Meiotic DMCI Recombinase by RAD51AP1 (2011) (0)
- Constitutive and inducible enhancer elements (1985) (0)
- Shu complex SWS1-SWSAP1 is required for mouse meiotic recombination in concert with the BRCA2 C terminus (2017) (0)
- Chromosomal Translocation Chromosomal Translocation Mechanisms and Consequences of Mechanisms and Consequences of (2006) (0)
- Abstract 2134: Unique and redundant roles of human RecQ homologs in cellular response to oxidative DNA damage (2012) (0)
- Abstract #LB-297: BRCA2 interaction with DSS1 is critical for homologous recombination (2009) (0)
- Abstract 2481: RAD51 and AICDA define a new synthetic lethal interaction that is targetable in multiple tumor types (2017) (0)
- BRCA2 promotes genomic integrity and therapy resistance primarily through its role in homology-directed repair (2023) (0)
- Abstract C09: Reduced proficiency in homologous recombination underlies the high sensitivity of embryonal carcinoma testicular germ cell tumors to cisplatin and poly (ADP-ribose) polymerase inhibition (2013) (0)
- Abstract 3020: Homology-directed repair in mouse mammary tissue (2015) (0)
- Abstract C51: High sensitivity of testicular germ cell tumors to PARP inhibitor olaparib alone and in combination with cisplatin (2011) (0)
- Modeling Oncogenic Translocations (2008) (0)
- ATR is required to complete meiotic recombination in mice (2018) (0)
- Development of a Novel Double-strand Break Repair Assay for High-throughput Small Molecule Screening in Glioma Cell Lines (2010) (0)
- Commentary Targeted transgenesis (2005) (0)
- Abstract A07: The RAD51 paralog complex SWS1-SWSAP1 is critical for homologous recombination in the mouse (2017) (0)
- CRISPR at lightning speeds (2020) (0)
- Genomic Complexity Profi ling Reveals That HORMAD1 Overexpression Contributes to Homologous Recombination Defi ciency in Triple-Negative Breast Cancers (2015) (0)
- Human ELG1 regulates the level of monoubiquitinated PCNA through interactions with PCNA, USP1, and polymerase η (2009) (0)
- Generating in vitro models of NTRK-fusion mesenchymal neoplasia as tools for investigating kinase oncogenic activation and response to targeted therapy (2023) (0)
- Evidence for reduced BRCA2 functional activity in Homo sapiens after divergence from the chimpanzee-human last common ancestor. (2022) (0)
- Mice Disrupted BRCA 1-PALB 2 Interaction in Male Fertility Defect Associated with Molecular Bases of Disease : (2014) (0)
- The control during storage of insect pest damage of corn seed (2000) (0)
- A Conversation with Maria Jasin. (2017) (0)
- Innovative Approaches for Determining the Role of BRCA2 and BRCA1 in DNA Recombinational Repair: Examination of Genetic Instability and Possible Therapeutic Uses (2000) (0)
- NHEJ-dependent recruitment of PR-Set7 to DNA double strand breaks facilitates H4K20 methylation and 53BP1 accumulation. (2014) (0)
- Abstract C52: Induction of homologous recombination by DNA nicks (2013) (0)
- Kondrashova, O. et al. (2017) Secondary somatic mutations restoring RAD51C and RAD51D associated with acquired resistance to the PARP inhibitor rucaparib in high-grade ovarian carcinoma. Cancer (2017) (0)
- Decision letter: A missense in HSF2BP causing primary ovarian insufficiency affects meiotic recombination by its novel interactor C19ORF57/BRME1 (2020) (0)
- Number : DAMD 1798-18334 TITLE : Innovative Approaches for Determining the Role of BRCA 2 and BRCA 1 in DNA Recombinational Repair : Examination of Genetic Instability and Possible Therapeutic Uses (0)
- Selection for Decreased BRCA2 Functional Activity in Homo sapiens After Divergence from the Chimpanzee-Human Last Common Ancestor (2020) (0)
- Abstract 3896: The interaction between BRCA2 and DSS1 is crucial for homologous recombination through controlling protein localization (2011) (0)
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What Schools Are Affiliated With Maria Jasin?
Maria Jasin is affiliated with the following schools:
