Marian Koshland
#54,924
Most Influential Person Now
American immunologist
Marian Koshland's AcademicInfluence.com Rankings
Marian Koshlandbiology Degrees
Biology
#4181
World Rank
#6273
Historical Rank
#1608
USA Rank
Immunology
#622
World Rank
#642
Historical Rank
#91
USA Rank
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Biology
Marian Koshland's Degrees
- PhD Biochemistry University of Chicago
Why Is Marian Koshland Influential?
(Suggest an Edit or Addition)According to Wikipedia, Marian Elliott "Bunny" Koshland was an American immunologist who discovered that the differences in amino acid composition of antibodies explain the efficiency and effectiveness with which they combat a huge range of foreign invaders.
Marian Koshland's Published Works
Published Works
- Synthesis of secreted and membrane-bound immunoglobulin mu heavy chains is directed by mRNAs that differ at their 3′ ends (1980) (472)
- Novel Subunit in Secretory IgA (1970) (260)
- The coming of age of the immunoglobulin J chain. (1985) (179)
- Structure and function of the J chain. (1975) (147)
- Ets-related protein PU.1 regulates expression of the immunoglobulin J-chain gene through a novel Ets-binding element. (1993) (135)
- An interleukin-2 signal relieves BSAP (Pax5)-mediated repression of the immunoglobulin J chain gene. (1996) (134)
- Mechanism of interleukin-2 signaling: mediation of different outcomes by a single receptor and transduction pathway. (1989) (134)
- Glycosylphosphatidylinositol: a candidate system for interleukin-2 signal transduction. (1991) (105)
- STRUCTURAL STUDIES OF HUMAN γG-MYELOMA PROTEINS OF DIFFERENT ANTIGENIC SUBGROUPS AND GENETIC SPECIFICITIES (1966) (94)
- A model system for peptide hormone action in differentiation: Interleukin 2 induces a B lymphoma to transcribe the J chain gene (1986) (94)
- Changes in J chain and mu chain RNA expression as a function of B cell differentiation (1984) (88)
- Role of disulfide interchange enzyme in immunoglobulin synthesis. (1981) (77)
- Polymer IgM assembly and secretion in lymphoid and nonlymphoid cell lines: evidence that J chain is required for pentamer IgM synthesis. (1995) (75)
- Immunoglobulin binding by mouse intestinal epithelial cell receptors. (1976) (74)
- Modification of amino acid residues in anti-p-azobenzenearsonic acid antibody during extensive iodination. (1963) (61)
- Molecular size and shape of the J chain from polymeric immunoglobulins. (1973) (58)
- Dependence of BSAP repressor and activator functions on BSAP concentration. (1998) (57)
- Expression of J chain RNA in cell lines representing different stages of B lymphocyte differentiation (1981) (57)
- Activation of antibody Fc function by antigen-induced conformational changes. (1975) (57)
- Mechanism of IgM polymerization. (1974) (56)
- Location of Specificity and Allotypic Amino Acid Residues in Antibody Fd Fragments (1967) (54)
- Differences in the amino acid composition of two purified antibodies from the same rabbit. (1963) (53)
- Primary structure of the immunoglobulin J chain from the mouse. (1982) (53)
- Secondary structure of the immunoglobulin J chain. (1985) (51)
- Identification of a lymphocyte enzyme that catalyzes pentamer immunoglobulin M assembly. (1981) (48)
- Assembly and secretion of pentameric IgM in a fusion between a nonsecreting B cell lymphoma and an IgG-secreting plasmacytoma. (1979) (46)
- Human monoclonal macroglobulins with specificity for Klebsiella K polysaccharides that contain 3,4-pyruvylated-D-galactose and 4,6- pyruvylated-D-galactose (1980) (45)
- Immunoglobulin J chain gene from the mouse. (1986) (45)
- B Cell-specific Activator Protein Prevents Two Activator Factors from Binding to the Immunoglobulin J Chain Promoter until the Antigen-driven Stages of B Cell Development* (1999) (45)
- Characterization of the J chain from polymeric immunoglobulins (IgA-IgM-immunological specificity-primary structure). (1972) (44)
- A stage-specific enhancer of immunoglobulin J chain gene is induced by interleukin-2 in a presecretor B cell stage. (1998) (42)
- Location of amino acid differences in the subunits of three rabbit antibodies. (1966) (42)
- Myocyte Enhancer Factor-related B-MEF2 Is Developmentally Expressed in B Cells and Regulates the Immunoglobulin J Chain Promoter* (1998) (42)
- Ig RNA expression in normal B cells stimulated with anti-IgM antibody and T cell-derived growth and differentiation factors (1984) (41)
- The stoichiometry of J chain in human secretory IgA. (1973) (40)
- The isolation and characterization of the V-H domain from rabbit heavy chains of different a locus allotype. (1975) (35)
- Expression of the J chain gene during B cell differentiation is inversely correlated with DNA methylation. (1981) (34)
- A promoter element that exerts positive and negative control of the interleukin 2-responsive J-chain gene. (1992) (33)
- The Transcription Factor NF-κB/p50 Interacts with the blkGene during B Cell Activation* (1998) (31)
- Evidence for multiple gene control of a single polypeptide chain: the heavy chain of rabbit immunoglobulin. (1969) (29)
- Differences in amino acid composition related to allotypic and antibody specificity of rabbit IgG heavy chains (1968) (26)
- A polypeptide chain from leopard shark 19S immunoglobulin analogous to mammalian J chain. (1971) (26)
- Evidence for a long-range conformational change induced by antigen binding to IgM antibody. (1977) (25)
- Linkage and assembly of polymeric IgA immunoglobulins. (1975) (24)
- J chain is encoded by a single gene unlinked to other immunoglobulin structural genes (1982) (22)
- Primary structure of immunoglobulins and its relationship to antibody specificity (1966) (21)
- Interleukin 2- and interleukin 5-induced changes in the binding of regulatory factors to the J-chain gene promoter. (1991) (21)
- Specific 5' and 3' regions of the mu-chain gene are undermethylated at distinct stages of B-cell differentiation. (1985) (21)
- Quantitative studies of the relationship between fecal and serum antibody. (1950) (21)
- Differences in the Amino Acid Composition of a Third Rabbit Antibody (1964) (19)
- Expression of the immunoglobulin J chain in a murine B lymphoma is driven by autocrine production of interleukin 2. (1996) (18)
- A GENERAL METHOD FOR THE LABELING OF THE ACTIVE SITE OF ANTIBODIES AND ENZYMES. (1959) (17)
- The transcription factor NF-kappaB/p50 interacts with the blk gene during B cell activation. (1998) (17)
- The effect of iodination on the binding of haptene to arsonic antibody. (1962) (15)
- Intracellular Events in the Differentiation of B Lymphocytes to Pentamer IgM Synthesis (1979) (15)
- Mechanism of antibody formation. I. Fate of 1131-labeled diphtheria toxoid at the site of antibody formation. (1957) (15)
- Antigen-induced conformational changes in IgM antibody. II. The role of the carrier. (1979) (13)
- Accessibility of the promoter sequence in the J-chain gene is regulated by chromatin changes during B-cell differentiation (1986) (13)
- Mechanism of immunoglobulin polymer assembly. (1974) (12)
- Identification of tyrosine at the active site of anti-p-azobenze-nearsonic acid antibody. (1963) (12)
- The origin of fecal antibody and its relationship to immunization with adjuvant. (1953) (11)
- Evidence against the universality of a tyrosyl residue at antibody combining sites. (1965) (10)
- Presidential address: molecular aspects of B cell differentiation. American Association of Immunologists April 1983. (1983) (10)
- Antigen-induced conformational changes in IgM antibody. I. The role of the antigenic determinant. (1979) (10)
- Selective proteolysis of the J chain component in human polymeric immunoglobulin. (1977) (9)
- Polymerization of human immunoglobulin M. (1978) (7)
- Molecular aspects of B cell differentiation (1983) (5)
- Amino acid differences between highly cross-reactive antibodies. (1970) (3)
- Mechanism of antibody formation. II. Rate of diphtheria antitoxin formation in the booster response. (1957) (3)
- Mechanism of antibody formation. III. Half-life of homologous diphtheria antitoxin in the guinea pig. (1957) (2)
- Differences in the Amino Acid Composition of a Third Rabbit Antibody. (1964) (2)
- Sheer luck made me an immunologist. (1996) (1)
- Structural studies of human IgG myeloma proteins of different antigenic subgroups and genetic specificities. (1968) (1)
- Modification of Amino Acid Residues in Arsonic Antibody During Extensive Iodination (1963) (0)
- Interleukin 2-and interleukin 5-induced changes in the binding of regulatory factors to the J-chain gene promoter ( B-cell Immune response / lymphokine nuclear signal / DNA blnding / trnsciptlonal activatlon / interleukin 4 ) (0)
- Expression of Fc Effector Function in Homogeneous Murine Anti-Ars IgM (1983) (0)
- The Booster Response (1959) (0)
- Antigen-induced Conformational Changes in IgM Antibody (2001) (0)
- Differentiation-specific methylation of the immunoglobulin heavy chain locus. (1985) (0)
- PROCEDURE FOR THE DETERMINATION OF PLUTONIUM IN URINE. Problem Assignment CX3-4 (1946) (0)
- Identification of Tyrosine at the Active Site of Arsonic Antibody (1963) (0)
- MECHANISM OF THE IMMUNE RESPONSE. Brookhaven Lecture Series, No. 42 (1964) (0)
- Mechanism of Antibody Formation (1957) (0)
- Mechanism of the immune response. BNL 912 (T-374). (1965) (0)
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