Mariana J. Kaplan
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Mexican-American rheumatologist
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Mariana J. Kaplan's Degrees
- Bachelors Biology Stanford University
- Doctorate Medicine Harvard University
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Why Is Mariana J. Kaplan Influential?
(Suggest an Edit or Addition)According to Wikipedia, Mariana J. Kaplan is a rheumatologist and physician-scientist. She researches mechanisms of immune dysregulation, organ damage, and premature vascular disease in systemic autoimmunity. Kaplan is chief of the systemic autoimmunity branch at the National Institute of Arthritis and Musculoskeletal and Skin Diseases.
Mariana J. Kaplan's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Netting Neutrophils Induce Endothelial Damage, Infiltrate Tissues, and Expose Immunostimulatory Molecules in Systemic Lupus Erythematosus (2011) (985)
- NETs Are a Source of Citrullinated Autoantigens and Stimulate Inflammatory Responses in Rheumatoid Arthritis (2013) (963)
- Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease (2015) (898)
- Neutrophil Extracellular Traps: Double-Edged Swords of Innate Immunity (2012) (867)
- Mast Cells and Neutrophils Release IL-17 through Extracellular Trap Formation in Psoriasis (2011) (784)
- A Distinct Subset of Proinflammatory Neutrophils Isolated from Patients with Systemic Lupus Erythematosus Induces Vascular Damage and Synthesizes Type I IFNs (2010) (571)
- Neutrophil Extracellular Trap–Associated Protein Activation of the NLRP3 Inflammasome Is Enhanced in Lupus Macrophages (2013) (368)
- Peptidylarginine Deiminase Inhibition Reduces Vascular Damage and Modulates Innate Immune Responses in Murine Models of Atherosclerosis (2014) (312)
- Little Peptide, Big Effects: The Role of LL-37 in Inflammation and Autoimmune Disease (2013) (307)
- Neutrophil extracellular traps induce endothelial dysfunction in systemic lupus erythematosus through the activation of matrix metalloproteinase-2 (2014) (306)
- Peptidylarginine deiminase inhibition is immunomodulatory and vasculoprotective in murine lupus. (2013) (304)
- Peptidylarginine deiminase inhibition disrupts NET formation and protects against kidney, skin and vascular disease in lupus-prone MRL/lpr mice (2014) (304)
- Somatic Mutations in UBA1 and Severe Adult-Onset Autoinflammatory Disease. (2020) (303)
- Demethylation of ITGAL (CD11a) regulatory sequences in systemic lupus erythematosus. (2002) (300)
- The role of neutrophils and NETosis in autoimmune and renal diseases (2016) (295)
- Low-density granulocytes: a distinct class of neutrophils in systemic autoimmunity (2013) (278)
- Endothelial cell apoptosis in systemic lupus erythematosus: a common pathway for abnormal vascular function and thrombosis propensity. (2004) (273)
- Neutrophils in the pathogenesis and manifestations of SLE (2011) (269)
- Decreased Ras-mitogen-activated protein kinase signaling may cause DNA hypomethylation in T lymphocytes from lupus patients. (2001) (269)
- Interferon-alpha promotes abnormal vasculogenesis in lupus: a potential pathway for premature atherosclerosis. (2007) (265)
- To NET or not to NET:current opinions and state of the science regarding the formation of neutrophil extracellular traps (2019) (243)
- VDAC oligomers form mitochondrial pores to release mtDNA fragments and promote lupus-like disease (2019) (227)
- Demethylation of Promoter Regulatory Elements Contributes to Perforin Overexpression in CD4+ Lupus T Cells1 (2004) (223)
- 18F‐Fluorodeoxyglucose–Positron Emission Tomography As an Imaging Biomarker in a Prospective, Longitudinal Cohort of Patients With Large Vessel Vasculitis (2018) (198)
- The Apoptotic Ligands TRAIL, TWEAK, and Fas Ligand Mediate Monocyte Death Induced by Autologous Lupus T Cells1 (2002) (173)
- Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis (2017) (168)
- Inflammasome Activation of IL-18 Results in Endothelial Progenitor Cell Dysfunction in Systemic Lupus Erythematosus (2011) (167)
- At the Bench: Neutrophil extracellular traps (NETs) highlight novel aspects of innate immune system involvement in autoimmune diseases (2016) (164)
- Photoacoustic imaging of early inflammatory response using gold nanorods (2007) (163)
- Severity of Psoriasis Associates With Aortic Vascular Inflammation Detected by FDG PET/CT and Neutrophil Activation in a Prospective Observational Study (2015) (163)
- Neutrophil Extracellular Trap–Derived Enzymes Oxidize High‐Density Lipoprotein: An Additional Proatherogenic Mechanism in Systemic Lupus Erythematosus (2014) (161)
- Lupus neutrophils: ‘NET’ gain in understanding lupus pathogenesis (2012) (160)
- Tofacitinib Ameliorates Murine Lupus and Its Associated Vascular Dysfunction (2017) (160)
- Thrombosis in patients with connective tissue diseases treated with specific cyclooxygenase 2 inhibitors. A report of four cases. (2000) (157)
- Role of neutrophils in systemic autoimmune diseases (2013) (157)
- Proteins derived from neutrophil extracellular traps may serve as self-antigens and mediate organ damage in autoimmune diseases (2012) (155)
- Aberrant Phenotype and Function of Myeloid Dendritic Cells in Systemic Lupus Erythematosus1 (2006) (146)
- Patients with COVID-19: in the dark-NETs of neutrophils (2021) (146)
- Epigenome profiling reveals significant DNA demethylation of interferon signature genes in lupus neutrophils. (2015) (136)
- TRAIL (Apo2 Ligand) and TWEAK (Apo3 Ligand) Mediate CD4+ T Cell Killing of Antigen-Presenting Macrophages1 (2000) (136)
- Potential benefits of green tea polyphenol EGCG in the prevention and treatment of vascular inflammation in rheumatoid arthritis. (2013) (133)
- Accelerated Macrophage Apoptosis Induces Autoantibody Formation and Organ Damage in Systemic Lupus Erythematosus1 (2006) (132)
- Cell death in the pathogenesis of systemic lupus erythematosus and lupus nephritis. (2017) (131)
- Type I interferons modulate vascular function, repair, thrombosis, and plaque progression in murine models of lupus and atherosclerosis. (2012) (129)
- Mechanisms of premature atherosclerosis in rheumatoid arthritis and lupus. (2013) (124)
- Type I Interferons Are Associated with Subclinical Markers of Cardiovascular Disease in a Cohort of Systemic Lupus Erythematosus Patients (2012) (122)
- The inflammasome and lupus: another innate immune mechanism contributing to disease pathogenesis? (2014) (121)
- The Detrimental Effects of IFN-α on Vasculogenesis in Lupus Are Mediated by Repression of IL-1 Pathways: Potential Role in Atherogenesis and Renal Vascular Rarefaction (2010) (121)
- Cardiovascular complications of rheumatoid arthritis: assessment, prevention, and treatment. (2010) (116)
- Transcriptomic, epigenetic, and functional analyses implicate neutrophil diversity in the pathogenesis of systemic lupus erythematosus (2019) (114)
- Cardiovascular disease in systemic lupus erythematosus: an update (2018) (112)
- Neutrophil subsets and their gene signature associate with vascular inflammation and coronary atherosclerosis in lupus. (2018) (110)
- The role of neutrophils in the pathogenesis of systemic lupus erythematosus (2015) (108)
- Neutrophil‐Related Gene Expression and Low‐Density Granulocytes Associated With Disease Activity and Response to Treatment in Antineutrophil Cytoplasmic Antibody–Associated Vasculitis (2015) (106)
- Neutrophils in Rheumatoid Arthritis: Breaking Immune Tolerance and Fueling Disease. (2019) (105)
- Deficiency of adenosine deaminase 2 triggers adenosine-mediated NETosis and TNF production in patients with DADA2. (2019) (89)
- Anti–Citrullinated Protein Antibodies Are Associated With Neutrophil Extracellular Traps in the Sputum in Relatives of Rheumatoid Arthritis Patients (2017) (87)
- A novel image-based quantitative method for the characterization of NETosis. (2015) (86)
- CD11b activation suppresses TLR-dependent inflammation and autoimmunity in systemic lupus erythematosus (2017) (83)
- Low-density granulocytes activate T cells and demonstrate a non-suppressive role in systemic lupus erythematosus (2019) (83)
- Neutrophil-Mediated IFN Activation in the Bone Marrow Alters B Cell Development in Human and Murine Systemic Lupus Erythematosus (2014) (81)
- An Essential Role of Caspase 1 in the Induction of Murine Lupus and Its Associated Vascular Damage (2014) (79)
- Placental histology and neutrophil extracellular traps in lupus and pre-eclampsia pregnancies (2016) (78)
- Neutrophil extracellular traps, B cells, and type I interferons contribute to immune dysregulation in hidradenitis suppurativa (2019) (77)
- Eculizumab (Alexion). (2002) (77)
- Cardiovascular disease in lupus: insights and updates (2013) (76)
- Hemodynamic, Autonomic, and Vascular Effects of Exposure to Coarse Particulate Matter Air Pollution from a Rural Location (2014) (75)
- Suboptimal cardiovascular risk factor identification and management in patients with rheumatoid arthritis: a cohort analysis (2012) (75)
- Photoacoustic and ultrasound dual-modality imaging of human peripheral joints (2012) (74)
- Increased asymmetric dimethylarginine and endothelin 1 levels in secondary Raynaud's phenomenon: implications for vascular dysfunction and progression of disease. (2003) (68)
- Management of cardiovascular disease risk in chronic inflammatory disorders (2009) (68)
- Myeloid-Specific Deletion of Peptidylarginine Deiminase 4 Mitigates Atherosclerosis (2018) (66)
- Interferon lambda promotes immune dysregulation and tissue inflammation in TLR7-induced lupus (2020) (66)
- Interleukin 17 as a novel predictor of vascular function in rheumatoid arthritis (2011) (65)
- Design, Synthesis, and Biological Evaluation of Tetrazole Analogs of Cl-Amidine as Protein Arginine Deiminase Inhibitors (2015) (64)
- Role of dendritic cells in the pathogenesis of systemic lupus erythematosus (2008) (63)
- Neutrophil extracellular traps mediate articular cartilage damage and enhance cartilage component immunogenicity in rheumatoid arthritis. (2020) (63)
- Sex differences in neutrophil biology modulate response to type I interferons and immunometabolism (2020) (62)
- The liver is a common non-exocrine target in primary Sjögren's syndrome: A retrospective review (2002) (62)
- Memory Stem T Cells in Autoimmune Disease: High Frequency of Circulating CD8+ Memory Stem Cells in Acquired Aplastic Anemia (2016) (62)
- Interferon‐α and Angiogenic Dysregulation in Pregnant Lupus Patients Who Develop Preeclampsia (2015) (60)
- Metabolic abnormalities and oxidative stress in lupus. (2017) (60)
- DEK-targeting DNA aptamers as therapeutics for inflammatory arthritis (2017) (60)
- Somatic Mutations in UBA1 Define a Distinct Subset of Relapsing Polychondritis Patients With VEXAS (2021) (59)
- Sera from patients with type 2 Diabetes and Neuropathy Induce Autophagy and Colocalization with Mitochondria in SY5Y cells (2005) (59)
- A role for muscarinic receptors in neutrophil extracellular trap formation and levamisole-induced autoimmunity. (2017) (58)
- Dysregulated neutrophil responses and neutrophil extracellular trap formation and degradation in PAPA syndrome (2018) (58)
- Phase 1 double-blind randomized safety trial of the Janus kinase inhibitor tofacitinib in systemic lupus erythematosus (2021) (58)
- A High-Throughput Real-Time Imaging Technique To Quantify NETosis and Distinguish Mechanisms of Cell Death in Human Neutrophils (2018) (57)
- Inhibition of Neutrophil Extracellular Trap Formation after Stem Cell Transplant by Prostaglandin E2. (2016) (56)
- Impaired translational response and increased protein kinase PKR expression in T cells from lupus patients. (2000) (56)
- Macrophage metabolic reprogramming presents a therapeutic target in lupus nephritis (2020) (55)
- Cardiovascular disease in rheumatoid arthritis (2006) (55)
- The interplay of inflammation and cardiovascular disease in systemic lupus erythematosus (2011) (55)
- The Peroxisome Proliferator Activated Receptor‐γ Pioglitazone Improves Vascular Function and Decreases Disease Activity in Patients With Rheumatoid Arthritis (2013) (55)
- Multicenter Systems Analysis of Human Blood Reveals Immature Neutrophils in Males and During Pregnancy (2017) (54)
- High density lipoprotein is targeted for oxidation by myeloperoxidase in rheumatoid arthritis (2013) (54)
- Peptidylarginine deiminases 2 and 4 modulate innate and adaptive immune responses in TLR-7-dependent lupus. (2018) (54)
- The Peroxisome Proliferator-Activated Receptor γ Agonist Pioglitazone Improves Cardiometabolic Risk and Renal Inflammation in Murine Lupus1 (2009) (53)
- Apoptosis in systemic lupus erythematosus. (2004) (53)
- Neutrophil Subsets, Platelets, and Vascular Disease in Psoriasis (2019) (53)
- Pathogenic immunity in systemic lupus erythematosus and atherosclerosis: common mechanisms and possible targets for intervention (2015) (51)
- Stimulatory and Inhibitory Killer Ig-Like Receptor Molecules Are Expressed and Functional on Lupus T Cells1 (2009) (50)
- Effects of cilostazol in patients with Raynaud's syndrome. (2003) (49)
- Update on cardiovascular disease in lupus (2016) (47)
- Neutrophil phenotypes and functions in cancer: A consensus statement (2022) (47)
- Immunity to commensal skin fungi promotes psoriasiform skin inflammation (2020) (47)
- Induction and Quantification of NETosis (2016) (46)
- New evidence for vascular disease in patients with early rheumatoid arthritis (2003) (46)
- Unraveling Vascular Inflammation: From Immunology to Imaging. (2017) (46)
- Systemic toxicity following administration of sirolimus (formerly rapamycin) for psoriasis: association of capillary leak syndrome with apoptosis of lesional lymphocytes. (1999) (45)
- Hepatocytes and neutrophils cooperatively suppress bacterial infection by differentially regulating lipocalin‐2 and neutrophil extracellular traps (2018) (44)
- Antibody Responses to Citrullinated and Noncitrullinated Antigens in the Sputum of Subjects With Rheumatoid Arthritis and Subjects at Risk for Development of Rheumatoid Arthritis (2018) (44)
- Vitamin D Deficiency, Interleukin 17, and Vascular Function in Rheumatoid Arthritis (2013) (43)
- Differential ubiquitination in NETs regulates macrophage responses in systemic lupus erythematosus (2018) (43)
- Prevalence of subclinical atherosclerosis is increased in systemic sclerosis and is associated with serum proteins: a cross-sectional, controlled study of carotid ultrasound. (2014) (43)
- Citrullinated Aggrecan Epitopes as Targets of Autoreactive CD4+ T Cells in Patients With Rheumatoid Arthritis (2019) (42)
- High‐Density Lipoprotein in Lupus: Disease Biomarkers and Potential Therapeutic Strategy (2020) (41)
- Differential ACPA Binding to Nuclear Antigens Reveals a PAD-Independent Pathway and a Distinct Subset of Acetylation Cross-Reactive Autoantibodies in Rheumatoid Arthritis (2019) (41)
- The “Infodemic” of COVID‐19 (2020) (40)
- Diapedesis-Induced Integrin Signaling via LFA-1 Facilitates Tissue Immunity by Inducing Intrinsic Complement C3 Expression in Immune Cells. (2020) (40)
- The role of aldosterone blockade in murine lupus nephritis (2008) (38)
- Safety and Tolerability of Omalizumab: A Randomized Clinical Trial of Humanized Anti‐IgE Monoclonal Antibody in Systemic Lupus Erythematosus (2019) (38)
- Lupus high-density lipoprotein induces proinflammatory responses in macrophages by binding lectin-like oxidised low-density lipoprotein receptor 1 and failing to promote activating transcription factor 3 activity (2016) (38)
- Neutrophil dysregulation is pathogenic in idiopathic inflammatory myopathies. (2020) (37)
- Targeting mitochondrial oxidative stress with MitoQ reduces NET formation and kidney disease in lupus-prone MRL-lpr mice (2020) (37)
- The peroxisome-proliferator activated receptor-γ agonist pioglitazone modulates aberrant T cell responses in systemic lupus erythematosus. (2013) (37)
- Dendritic cells and the immunopathogenesis of systemic lupus erythematosus (2007) (36)
- The Role of Neutrophils and Neutrophil Extracellular Traps in Vascular Damage in Systemic Lupus Erythematosus (2019) (35)
- Bite of the wolf: innate immune responses propagate autoimmunity in lupus. (2021) (35)
- How does interferon-α insult the vasculature? Let me count the ways. (2011) (34)
- Improved Mitochondrial Metabolism and Reduced Inflammation Following Attenuation of Murine Lupus With Coenzyme Q10 Analog Idebenone (2020) (33)
- Haploinsufficiency of NADPH Oxidase Subunit Neutrophil Cytosolic Factor 2 Is Sufficient to Accelerate Full‐Blown Lupus in NZM 2328 Mice (2017) (33)
- Revealing the cellular degradome by mass spectrometry analysis of proteasome-cleaved peptides (2018) (32)
- Proteomic, biomechanical and functional analyses define neutrophil heterogeneity in systemic lupus erythematosus (2020) (31)
- Leflunomide Aventis Pharma. (2001) (31)
- Brief Report: Endothelial Progenitor Cell Phenotype and Function Are Impaired in Childhood‐Onset Systemic Lupus Erythematosus (2015) (31)
- Premature vascular damage in systemic lupus erythematosus (2009) (31)
- Brief Report: Vitamin D Deficiency Is Associated With Endothelial Dysfunction and Increases Type I Interferon Gene Expression in a Murine Model of Systemic Lupus Erythematosus (2016) (31)
- Modulation of Cardiometabolic Disease Markers by Type I Interferon Inhibition in Systemic Lupus Erythematosus (2020) (30)
- Brief Report: Drugs Implicated in Systemic Autoimmunity Modulate Neutrophil Extracellular Trap Formation (2018) (29)
- Neutrophil-mediated carbamylation promotes articular damage in rheumatoid arthritis (2020) (29)
- The effect of acute exposure to coarse particulate matter air pollution in a rural location on circulating endothelial progenitor cells: results from a randomized controlled study (2013) (29)
- Correction: A Distinct Subset of Proinflammatory Neutrophils Isolated from Patients with Systemic Lupus Erythematosus Induces Vascular Damage and Synthesizes Type I IFNs (2010) (29)
- Brief Report: Deficiency of Complement 1r Subcomponent in Early‐Onset Systemic Lupus Erythematosus: The Role of Disease‐Modifying Alleles in a Monogenic Disease (2017) (28)
- Women in academic rheumatology. (2005) (27)
- Oxidative DNA Damage Accelerates Skin Inflammation in Pristane-Induced Lupus Model (2020) (26)
- Accelerated model of lupus autoimmunity and vasculopathy driven by toll-like receptor 7/9 imbalance (2018) (26)
- Demethylation of ITGAL ( CD 11 a ) Regulatory Sequences in Systemic Lupus Erythematosus (2002) (25)
- Interleukin 10 hampers endothelial cell differentiation and enhances the effects of interferon α on lupus endothelial cell progenitors. (2015) (25)
- Review: Neutrophils as Invigorated Targets in Rheumatic Diseases (2016) (25)
- Myeloid dendritic cells display downregulation of C-type lectin receptors and aberrant lectin uptake in systemic lupus erythematosus (2008) (24)
- LFA-1 overexpression and T cell autoreactivity: mechanisms. (2000) (24)
- Real‐time deformability cytometry reveals sequential contraction and expansion during neutrophil priming (2019) (23)
- Dysfunction of endothelial progenitor cells is associated with the type I IFN pathway in patients with polymyositis and dermatomyositis. (2016) (23)
- Plasminogen Activator Inhibitor‐1 Is Associated with Impaired Endothelial Function in Women with Systemic Lupus Erythematosus (2005) (23)
- Genomic alterations in abnormal neutrophils isolated from adult patients with systemic lupus erythematosus (2014) (23)
- Disentangling the role of neutrophil extracellular traps in rheumatic diseases. (2017) (21)
- Detection of SLE antigens in neutrophil extracellular traps (NETs). (2014) (21)
- Interferon lambda in inflammation and autoimmune rheumatic diseases (2021) (21)
- Deadliest catch: neutrophil extracellular traps in autoimmunity. (2019) (19)
- DNA methylation in the regulation of T cell LFA-1 expression. (2000) (19)
- NETs spread ever wider in rheumatic diseases (2019) (19)
- Genome-wide DNA methylation analysis in primary antiphospholipid syndrome neutrophils. (2018) (19)
- Stimulatory and Inhibitory Killer Ig-Like Receptor Molecules Are Expressed and Functional on Lupus T Cells (2009) (18)
- The coenzyme Q10 analog idebenone attenuates murine lupus by improving mitochondrial metabolism and reducing inflammation. (2019) (18)
- Cardiometabolic risk in psoriasis: differential effects of biologic agents (2008) (17)
- Single-Cell Analysis Reveals the Range of Transcriptional States of Circulating Human Neutrophils (2022) (17)
- Neutrophil extracellular traps in systemic autoimmune and autoinflammatory diseases (2022) (17)
- PAM3 supports the generation of M2-like macrophages from lupus patient monocytes and improves disease outcome in murine lupus. (2019) (17)
- Determinants of Vascular Function in Patients With Chronic Gout (2011) (16)
- Premature vascular damage in systemic lupus erythematosus: an imbalance of damage and repair? (2009) (16)
- A highlight from the LUPUS 2014 meeting: eight great ideas (2015) (16)
- Effects of Gasdermin D in Modulating Murine Lupus and its Associated Organ Damage (2020) (16)
- Brief Report: Defining the Nasal Transcriptome in Granulomatosis With Polyangiitis (Wegener's) (2015) (16)
- Association between anti-interferon-alpha autoantibodies and COVID-19 in systemic lupus erythematosus (2020) (15)
- RNA Externalized by Neutrophil Extracellular Traps Promotes Inflammatory Pathways in Endothelial Cells (2021) (14)
- Neutrophils in the Pathogenesis of Rheumatic Diseases: Fueling the Fire (2020) (14)
- Association Between Soluble Lectinlike Oxidized Low-Density Lipoprotein Receptor-1 and Coronary Artery Disease in Psoriasis. (2019) (13)
- Use of Magnetic Resonance Imaging to Identify Immune Checkpoint Inhibitor–Induced Inflammatory Arthritis (2020) (13)
- Association of lipoprotein subfractions and glycoprotein acetylation with coronary plaque burden in SLE (2019) (13)
- Brief Report: A Novel ELANE Mutation Associated With Inflammatory Arthritis, Defective NETosis, and Recurrent Parvovirus Infection (2017) (13)
- Alterations in nuclear structure promote lupus autoimmunity in a mouse model (2016) (12)
- In vivo imaging of inflammatory responses by photoacoustics using cell-targeted gold nanorods (GNR) as contrast agent (2008) (11)
- Using the circulating proteome to assess type I interferon activity in systemic lupus erythematosus (2017) (11)
- Correspondence on ‘Clinical course of coronavirus disease 2019 (COVID-19) in a series of 17 patients with systemic lupus erythematosus under long-term treatment with hydroxychloroquine’ (2021) (10)
- Immunometabolism in the pathogenesis of systemic lupus erythematosus: an update (2020) (10)
- Neutrophils as Drivers of Immune Dysregulation in Autoimmune Diseases with Skin Manifestations. (2021) (10)
- Endothelial damage and autoimmune diseases (2009) (10)
- Specimen Collection for Translational Studies in Hidradenitis Suppurativa (2019) (10)
- Autoantibodies present in Hidradenitis suppurativa correlate with disease severity and promote release of proinflammatory cytokines in macrophages. (2021) (10)
- The development of depressive symptoms during medical internship stress predicts worsening vascular function. (2015) (10)
- 183 A phase 1B/2A trial of tofacitinib, an oral janus kinase inhibitor, in systemic lupus erythematosus (2019) (10)
- Cholesterol-Induced M4-Like Macrophages Recruit Neutrophils and Induce NETosis (2021) (9)
- Association of Sputum Neutrophil Extracellular Trap Subsets With IgA Anti–Citrullinated Protein Antibodies in Subjects at Risk for Rheumatoid Arthritis (2021) (9)
- The mechanics of myeloid cells (2020) (9)
- Lupus-like autoimmunity and increased interferon response in patients with STAT3-deficient hyper-IgE syndrome. (2020) (9)
- Multicenter analysis of neutrophil extracellular trap dysregulation in adult and pediatric COVID-19 (2022) (8)
- Editorial: NETosis 2: The Excitement Continues (2017) (8)
- Response to comment on “Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis” (2018) (8)
- Technical comment on “Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis” (2018) (8)
- FK-778 Astellas. (2005) (8)
- Cardiovascular disease risk and pathogenesis in systemic lupus erythematosus (2022) (7)
- CD 11 b activation suppresses TLR-dependent inflammation and autoimmunity in systemic lupus erythematosus (2017) (7)
- Boosting NAD+ blunts TLR4-induced type I IFN in control and systemic lupus erythematosus monocytes (2022) (7)
- Use of Sensory Stimulation with Alzheimer Patients in a Garden Setting (1994) (7)
- Is rheumatoid arthritis a risk factor for cardiovascular disease? (2007) (7)
- Interferon-alpha and angiogenic dysregulation in pregnant lupus patients destined for preeclampsia (2014) (6)
- Neutrophil Dysregulation in the Pathogenesis of Systemic Lupus Erythematosus. (2021) (6)
- Extracellular Chromatin Traps Interconnect Cell Biology, Microbiology, and Immunology (2013) (6)
- Modulation of the Itaconate Pathway Attenuates Murine Lupus (2022) (5)
- Multicenter analysis of neutrophil extracellular trap dysregulation in adult and pediatric COVID-19 (2022) (5)
- Anti-Carbamylated LL37 Antibodies Promote Pathogenic Bone Resorption in Rheumatoid Arthritis (2021) (5)
- Low‐density granulocytes in systemic autoimmunity and autoinflammation (2022) (4)
- Equity and diversity in academic medicine: a perspective from the JCI editors. (2019) (4)
- Potential bene fi ts of green tea polyphenol EGCG in the prevention and treatment of vascular in fl ammation in rheumatoid arthritis (2013) (4)
- Achilles Tendinopathy After Treatment with Ophthalmic Moxifloxacin (2013) (4)
- Jumbled NETs promote vasculitis. (2012) (4)
- OP0174 Alteration of mediators of vascular inflammation by anifrolumab in the phase iib muse study in sle (2018) (4)
- Functional on Lupus T Cells Receptor Molecules Are Expressed and Stimulatory and Inhibitory Killer Ig-Like (2009) (3)
- High Frequency of Circulating CD8+ Memory Stem T Cells in Acquired Aplastic Anemia (2015) (3)
- Psoriasis through Extracellular Trap Formation in Mast Cells and Neutrophils Release IL-17 (2011) (3)
- NETosis 2: The Excitement Continues (2017) (3)
- Induced by Autologous Lupus T Cells and Fas Ligand Mediate Monocyte Death The Apoptotic Ligands TRAIL, TWEAK, (2002) (3)
- Linking clotting and autoimmunity (2021) (2)
- NETched in Stone. (2019) (2)
- Neutrophil extracellular trap-associated carbamylation and histones trigger osteoclast formation in rheumatoid arthritis (2023) (2)
- Mitochondria shape neutrophils during hypoxia. (2022) (2)
- Targeting the Myddosome in Systemic Autoimmunity: Ready for Prime Time? (2021) (1)
- Tissue extravasation/LFA-1 induces ‘complement C3-licensing’ required for successful Th1 responses (2018) (1)
- Mechanisms of vascular damage in systemic lupus erythematosus (2021) (1)
- Peroxisome proliferator activated receptor-γ agonist pioglitazone improves vascular and metabolic dysfunction in systemic lupus erythematosus (2022) (1)
- GG-10 Imagine SLE: international multi-site assessment of genetics and inflammation in early onset and familial systemic lupus erythematosus (2016) (1)
- Abstract 11890: S100A8/A9 is Increased in Psoriasis Serum, Relates to Vascular Diseases and Activates Human Endothelial Cells (2015) (1)
- 652 Role of fungi and extracellular matrix in hidradenitis suppurativa (2017) (1)
- Constitutively active Lyn kinase causes a cutaneous small vessel vasculitis and liver fibrosis syndrome (2022) (1)
- The Peroxisome Proliferator Activated Receptor-c Pioglitazone Improves Vascular Function and Decreases Disease Activity in Patients With Rheumatoid Arthritis (2013) (1)
- Diseases of blood vessels: Immune system involvement in vasculitis and vasculopathy (2022) (1)
- Coexisting autoantibodies against transcription factor Sp4 are associated with decreased cancer risk in patients with dermatomyositis with anti-TIF1γ autoantibodies (2022) (1)
- Quantification of Neutrophils Undergoing NET Formation and Distinguishing Mechanisms of Neutrophil Cell Death by Use of a High-Throughput Method. (2022) (1)
- FOXM1 network in association with TREM1 suppression regulates NET formation in diabetic foot ulcers (2022) (1)
- Inflammatory Responses in Rheumatoid Arthritis NETs Are a Source of Citrullinated Autoantigens and Stimulate (2013) (1)
- Chapter 15 – Mechanisms of Acute Inflammation and Vascular Injury in SLE (2012) (1)
- Diffuse swelling of one finger in a patient with metastatic breast cancer. (2000) (1)
- Neutralizing anti-DNase 1 and DNase 1L3 antibodies impair neutrophil extracellular traps degradation in Hidradenitis suppurativa. (2022) (1)
- OP0054 Neuroimmunomodulation of Neutrophils as A Novel Mechanism of Levamisole-Induced Vasculitis (2016) (1)
- Do tumor-necrosis-factor inhibitors prevent first cardiovascular events in patients with rheumatoid arthritis? (2005) (1)
- Pathogenesis of Accelerated Atherosclerosis and Vascular Injury in Systemic Lupus Erythematosus (2019) (1)
- Distinct pathogenic roles for resident and monocyte-derived macrophages in lupus nephritis (2022) (1)
- Scalable clustering with supervised linkage methods (2021) (1)
- Response to: ‘Neutrophil extracellular traps and low-density granulocytes are associated with the interferon signature in systemic lupus erythematosus, but not in antiphospholipid syndrome’ by van den Hoogen et al (2019) (1)
- CHAPTER 48 – Cellular Hematology (2011) (1)
- Changes in cardiorespiratory function and fatigue following 12 weeks of exercise training in women with systemic lupus erythematosus: a pilot study (2022) (0)
- Editorial introductions. (2017) (0)
- Metabolic alterations of the immune system in the pathogenesis of autoimmune diseases (2023) (0)
- II-18 Cell-based therapy in system lupus erythematosus (SLE): effects on neutrophil netting (2016) (0)
- Of larks and owls (2020) (0)
- Inflammation in Murine Lupus Cardiometabolic Risk and Renal Agonist Pioglitazone Improves g Receptor The Peroxisome Proliferator-Activated (2009) (0)
- CS-24 Association of lipoprotein subfractions and glycoprotein acetylation with coronary plaque burden in systemic lupus erythematosus (2018) (0)
- 953 Adaptive responses to skin microbe control the pathogenesis of experimental psoriasis (2018) (0)
- CD11b activation protects against lupus nephritis by suppressing TLR-dependent IFN responses via AKT-FOXO3-IRF7 (2017) (0)
- CT-08 Safety and tolerability of omalizumab, a humanized anti-IgE monoclonal antibody in systemic lupus erythematosus (STOP LUPUS) (2018) (0)
- 740 IgG autoantibodies correlate with Hidradenitis Suppurativa clinical severity (2020) (0)
- The interplay of infl ammation and cardiovascular disease in systemic lupus erythematosus (2011) (0)
- Myeloid cells and atherosclerosis in systemic lupus erythematosus Neutrophils (2016) (0)
- Neutrophil extracellular traps as a source of high density lipoprotein oxidation in lupus-related cardiovascular disease. (HUM1P.312) (2014) (0)
- HAL-X: Scalable hierarchical clustering for rapid and tunable single-cell analysis (2022) (0)
- Spleen tyrosine kinase inhibition restores myeloid homeostasis in COVID-19 (2023) (0)
- Coexisting autoantibodies against transcription factor Sp4 are associated with decreased cancer risk in dermatomyositis patients with anti-TIF1gamma autoantibodies (2022) (0)
- FRI0279 Decreased sphingosin-1-phosphate receptor 1 (S1P1) expression in endothelial progenitor cells (EPCS) from systemic lupus erythematosus (SLE) patients (2018) (0)
- Arthritis & Rheumatology: Evolving to Meet the Challenges of Rheumatology (2020) (0)
- Inflammasome Is Enhanced in Lupus Protein Activation of the NLRP3 Associated − Neutrophil Extracellular Trap (2013) (0)
- pathway for premature atherosclerosis promotes abnormal vasculogenesis in lupus: a potential α Interferon- (2013) (0)
- FRI0053 Antibodies to a subset of citrullinated peptide antigens correlate with neutrophil extracellular trap levels in the sputum of subjects at-risk for future ra (2017) (0)
- List of Contributors (2019) (0)
- Using the circulating proteome to assess type I interferon activity in systemic lupus erythematosus (2020) (0)
- The Rheumatism Society of the District of Columbia (2018) (0)
- 23 Treating lupus-prone mice with a coenzyme Q10 analog decreases disease parameters indicating a therapeutic role in systemic lupus erythematosus (2019) (0)
- A novel real-time imaging technique to quantify mechanisms of cell death in neutrophils (2017) (0)
- Reply: To PMID 24449582. (2014) (0)
- Oral idebenone attenuates murine lupus (2017) (0)
- Reply (2022) (0)
- To NET or not to NET:current opinions and state of the science regarding the formation of neutrophil extracellular traps (2019) (0)
- Reply to letter by Haung and Xu: itaconate for lupus remission. (2022) (0)
- 738 Friend or foe: Elevated sera levels of IgM autoantibodies targeting hair follicle components detected in patients with Hidradenitis Suppurativa (2020) (0)
- Cilostazol in Raynaud s disease: A double-blind placebo controlled clinical trial (2003) (0)
- 1044. Identification and Characterization of an Unconventional NK Subset in COVID-19 (2022) (0)
- Response to Comment on “Inflammasome Activation of IL-18 Results in Endothelial Progenitor Cell Dysfunction in Systemic Lupus Erythematosus” (2012) (0)
- Multi-Omic Profiling Reveals Immune Cell Priming Signature Linked to Lupus Prognosis (2022) (0)
- Abstract 16374: Low Density Granulocytes Associate With Non-Calcified Coronary Plaque in Psoriasis (2017) (0)
- This information is current as Erythematosus Dendritic Cells in Systemic Lupus Aberrant Phenotype and Function of Myeloid (2006) (0)
- Lupus T Cells + Overexpression in CD4 Elements Contributes to Perforin Demethylation of Promoter Regulatory (2004) (0)
- 38 Redox-driven type I interferon in SLE and its treatment with MitoQ (2019) (0)
- Editorial overview: Autoimmunity 2022. (2023) (0)
- Reply (2014) (0)
- Unraveling Vascular Inflammation (0)
- IFNsVascular Damage and Synthesizes Type I Systemic Lupus Erythematosus Induces Neutrophils Isolated from Patients with A Distinct Subset of Proinflammatory (2010) (0)
- 693 A closer look: Understanding the role of lesional fibroblasts in hidradenitis suppurativa (2022) (0)
- Modulation of macrophage responses by aberrant lipoproteins in chronic inflammatory diseases. (HUM3P.241) (2015) (0)
- Neutrophil extracellular traps are a source of citrullinated autoantigens and stimulate inflammatory responses in rheumatoid arthritis (P4061) (2013) (0)
- Vitamin D Deficiency Is Associated With Endothelial Dysfunction and Increases Type-1 Interferon Gene Expression in a Murine Model of SLE (2019) (0)
- Modulation of TLR2/1 by PAM3CSK4 to induce generation of immunosuppressive macrophages as a therapeutic approach for SLE (2018) (0)
- NETosis: At the Intersection of Cell Biology, Microbiology, and Immunology (2013) (0)
- Length Running head : Aggrecan as an RA autoantigen Title : Citrullinated Aggrecan Epitopes as Targets of Auto-reactive CD 4 + T cells in Patients with Rheumatoid Arthritis (2018) (0)
- Editorial introductions. (2016) (0)
- Human LUBAC deficiency leads to autoinflammation and immunodeficiency by dysregulation in TNF-mediated cell death (2022) (0)
- Mitochondrial dysfunction in the erythroid compartment (2021) (0)
- SP0181 Detrimental effects of interferon alpha on angiogenesis (2013) (0)
- Arthritis & Rheumatology: “Mid‐Term” Report (2022) (0)
- This information is current as Anemia Memory Stem Cells in Acquired Aplastic + Disease : High Frequency of Circulating CD 8 Memory Stem T Cells in Autoimmune (2016) (0)
- This information is current as Macrophages Inflammasome Is Enhanced in Lupus Protein Activation of the NLRP 3 Associated − Neutrophil Extracellular Trap (2012) (0)
- Diapedesis and LFA-1 mediate tissue immune cell effector activity via intrinsic complement C3 licensing (2020) (0)
- Polymorphonuclear cells (2021) (0)
- 1018 Neutrophil extracellular traps and type 1 IFN contribute to autoimmunity in hidradenitis suppurativa (2018) (0)
- II-17 Lupus HDL promotes pro-inflammatory responses in macrophages through LOX1R binding and abrogation of ATF3 activity (2016) (0)
- Endothelial Progenitor Cell Dysfunction in Inflammasome Activation of IL-18 Results in (2011) (0)
- Of larks and owls (2020) (0)
- Apoptosis-induced nuclear expulsion in tumor cells drives S100a4-mediated metastatic outgrowth through the RAGE pathway (2023) (0)
- Casting a Wide NET (2022) (0)
- AB0024 A novel real-time imaging technique to characterize mechanisms of cell death in neutrophils (2017) (0)
- 269 Vitamin D Deficiency Promotes Vascular Damage and Disease Activity in a Murine Model of Systemic Lupus Erythematosus (2016) (0)
- in Systemic Lupus Erythematosus Autoantibody Formation and Organ Damage Accelerated Macrophage Apoptosis Induces (2006) (0)
- II-09 SLE bone marrow contains factors that promote type I interferon activation (2016) (0)
- Low-density granulocytes: a distinct class of neutrophils in systemic autoimmunity (2013) (0)
- 08.43 Antibodies to a subset of citrullinated peptide antigens correlate with neutrophil extracellular trap levels in the sputum of subjects at-risk for future ra (2017) (0)
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