Marion Sewer

Q: What Schools Are Affiliated With Marion Sewer

Marion Sewer is affiliated with the following schools: University of California, Berkeley, Emory University, University of California, San Diego, Stanford University, Georgia Tech, University of California, San Francisco

Marion Sewer's AcademicInfluence.com Rankings

Marion Sewer

Medical

#3746

World Rank

#4252

Historical Rank

#565

USA Rank

Pharmacology

#504

World Rank

#563

Historical Rank

#53

USA Rank

medical Degrees

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Medical

Marion Sewer's Degrees

Bachelors Pharmacology University of California, Berkeley
PhD Pharmacology University of California, San Francisco

Why Is Marion Sewer Influential?

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According to Wikipedia, Marion Sewer was a pharmacologist and professor at the University of California, San Diego's Skaggs School of Pharmacy and Pharmaceutical Sciences known for her research on steroid hormone biogenesis and her commitment to increasing diversity in science. Much of her research centered around cytochrome P450, a family of enzymes involved in the conversion of cholesterol into steroid hormones. She died unexpectedly at the age of 43 from a pulmonary embolism on January 28, 2016, while traveling through the Detroit airport.

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Marion Sewer's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

ACTH modulation of transcription factors responsible for steroid hydroxylase gene expression in the adrenal cortex (2003) (190)
Transcriptional Activation of Human CYP17 in H295R Adrenocortical Cells Depends on Complex Formation among p54nrb/NonO, Protein-Associated Splicing Factor, and SF-1, a Complex That Also Participates in Repression of Transcription. (2002) (103)
Modulation of cytochrome P-450 gene expression in endotoxemic mice is tissue specific and peroxisome proliferator-activated receptor-alpha dependent. (1999) (100)
Endotoxemia in rats is associated with induction of the P4504A subfamily and suppression of several other forms of cytochrome P450. (1996) (99)
Nitric oxide-independent suppression of P450 2C11 expression by interleukin-1beta and endotoxin in primary rat hepatocytes. (1997) (93)
Down-regulation of the expression of three major rat liver cytochrome P450S by endotoxin in vivo occurs independently of nitric oxide production. (1998) (85)
Genistein Stimulates MCF-7 Breast Cancer Cell Growth by Inducing Acid Ceramidase (ASAH1) Gene Expression* (2011) (81)
Sphingosine regulates the transcription of CYP17 by binding to steroidogenic factor-1. (2006) (79)
Down-regulation of cytochrome P450 mRNAs and proteins in mice lacking a functional NOS2 gene. (1998) (78)
Adrenocorticotropin/cyclic adenosine 3',5'-monophosphate-mediated transcription of the human CYP17 gene in the adrenal cortex is dependent on phosphatase activity. (2002) (77)
Transcriptional activation of human CYP17 in H295R adrenocortical cells depends on complex formation among p54(nrb)/NonO, protein-associated splicing factor, and SF-1, a complex that also participates in repression of transcription. (2002) (73)
Differential inductive and suppressive effects of endotoxin and particulate irritants on hepatic and renal cytochrome P-450 expression. (1997) (72)
cAMP-dependent Protein Kinase Enhances CYP17 Transcription via MKP-1 Activation in H295R Human Adrenocortical Cells* (2003) (71)
Modulation of drug metabolism in infectious and inflammatory diseases. (1999) (71)
Physiological and pathophysiological regulation of cytochrome P450. (1998) (66)
Steroidogenic factor-1 is a sphingolipid binding protein (2007) (65)
Nuclear sphingolipid metabolism. (2012) (63)
Regulation of Steroid Hormone Biosynthesis by the Cytoskeleton (2008) (58)
Cyclic AMP-Stimulated Interaction between Steroidogenic Factor 1 and Diacylglycerol Kinase θ Facilitates Induction of CYP17 (2007) (56)
Cyclic adenosine 5'-monophosphate-dependent sphingosine-1-phosphate biosynthesis induces human CYP17 gene transcription by activating cleavage of sterol regulatory element binding protein 1. (2006) (51)
Transcriptional Regulation of Adrenocortical Steroidogenic Gene Expression (2007) (50)
Coregulator exchange and sphingosine-sensitive cooperativity of steroidogenic factor-1, general control nonderepressed 5, p54, and p160 coactivators regulate cyclic adenosine 3',5'-monophosphate-dependent cytochrome P450c17 transcription rate. (2007) (49)
cAMP-dependent transcription of steroidogenic genes in the human adrenal cortex requires a dual-specificity phosphatase in addition to protein kinase A. (2002) (46)
Multiple roles for sphingolipids in steroid hormone biosynthesis. (2008) (44)
Insights into the Transcriptional Regulation of Steroidogenic Enzymes and StAR (2001) (42)
Regulation of hepatic cytochrome P450 2C11 by glucocorticoids. (1997) (40)
Oxysterol-related-binding-protein related Protein-2 (ORP2) regulates cortisol biosynthesis and cholesterol homeostasis (2016) (36)
The interplay between bioactive sphingolipids and steroid hormones (2010) (32)
Phosphorylation of CtBP1 by cAMP-dependent Protein Kinase Modulates Induction of CYP17 by Stimulating Partnering of CtBP1 and 2* (2008) (31)
Acid ceramidase (ASAH1) is a global regulator of steroidogenic capacity and adrenocortical gene expression. (2012) (29)
Sphingosine-1-phosphate rapidly increases cortisol biosynthesis and the expression of genes involved in cholesterol uptake and transport in H295R adrenocortical cells (2012) (29)
RhoA and DIAPH1 mediate adrenocorticotropin-stimulated cortisol biosynthesis by regulating mitochondrial trafficking. (2010) (29)
Resveratrol stimulates cortisol biosynthesis by activating SIRT-dependent deacetylation of P450scc. (2012) (29)
Characterization of CYP4A induction in rat liver by inflammatory stimuli: dependence on sex, strain, and inflammation-evoked hypophagia. (2001) (29)
Complex assembly on the human CYP17 promoter (2009) (26)
ACTH Regulates Steroidogenic Gene Expression and Cortisol Biosynthesis in the Human Adrenal Cortex via Sphingolipid Metabolism (2004) (26)
p54nrb/NONO Regulates Cyclic AMP-Dependent Glucocorticoid Production by Modulating Phosphodiesterase mRNA Splicing and Degradation (2015) (26)
Acid Ceramidase (ASAH1) Represses Steroidogenic Factor 1-Dependent Gene Transcription in H295R Human Adrenocortical Cells by Binding to the Receptor (2012) (25)
The cAMP-responsive element binding protein (CREB) regulates the expression of acid ceramidase (ASAH1) in H295R human adrenocortical cells. (2009) (22)
Sphingosine-1-phosphate regulates the expression of the liver receptor homologue-1 (2008) (20)
Diacylglycerol kinase θ couples farnesoid X receptor-dependent bile acid signalling to Akt activation and glucose homoeostasis in hepatocytes. (2013) (19)
Silencing diacylglycerol kinase-theta expression reduces steroid hormone biosynthesis and cholesterol metabolism in human adrenocortical cells. (2014) (17)
cAMP-stimulated phosphorylation of diaphanous 1 regulates protein stability and interaction with binding partners in adrenocortical cells (2013) (17)
Regulation of adrenocortical steroid hormone production by RhoA–diaphanous 1 signaling and the cytoskeleton (2013) (16)
cAMP-stimulated transcription of DGKθ requires steroidogenic factor 1 and sterol regulatory element binding protein 1 (2013) (12)
TRANSCRIPTIONAL COMPLEXES AT THE CYP17 CRS (2002) (12)
Multiple Signaling Pathways Coordinate CYP17 Gene Expression in the Human Adrenal Cortex. (2008) (5)
AKAP13 coordinates cAMP signaling and glucocorticoid production in H295R human adrenocortical cells (612.2) (2014) (2)
PHYSIOLOGICAL AND PATHOPHYSIOLOGICAL REGULATION OF CYTOCHROME P 450 (1998) (2)
Oxysterol‐Related Binding Proteins Regulate Glucocorticoid Production and Cholesterol Metabolism in H295R Human Adrenocortical Cells (2013) (0)
PMA stimulates PKCalpha‐dependent phosphorylation of ASAH1 in breast cancer cell lines. (2013) (0)
cAMP‐stimulated Expression of DGKθ Requires Steroidogenic Factor‐1 and Sterol Regulatory Element Binding Protein (2013) (0)
cAMP stimulates diacylglycerol kinase‐θ phosphorylation in adrenocortical cells (605.18) (2014) (0)
cAMP represses LPIN1 protein expression in human adrenocortical cells (2013) (0)
Diaphanous 1 Negatively Regulates Cortisol Biosynthesis in H295R Human Adrenocortical Cells (2012) (0)
Phosphorylation of CtBP1 by PKA Induces CYP17 by Promoting CtBP Heterooligomerization (2008) (0)
ACTH/cAMP regulates the expression of acid ceramidase (ASAH1) in H295R human adrenocortical cells (2008) (0)
Acid Ceramidase Represses Steroidogenic Factor 1‐dependent Gene Transcription by Binding to the Receptor in the Nucleus of H295R Human Adrenocortical Cells (2012) (0)
p54nrb/NONO regulates cAMP signaling and cortisol production by modulating phosphodiesterase splicing (1013.21) (2014) (0)
Adrenocorticotropin‐Stimulated Phosphorylation of RhoA Facilitates Binding to mDia1, Mitochondrial Trafficking, and Cortisol Biosynthesis (2008) (0)
Coordinating the Stress Response: Mechanisms Regulating Cortisol Production (2012) (0)
Bile Acids Induce Diacyglycerol Kinase‐θ Expression in HepG2 liver Cells (2012) (0)
Regulation of Glucocorticoid Production by Nuclear Lipid Metabolism (2013) (0)
Bile Acids Modulate Steroidogenic Gene Expression in H295R Adrenocortical Cells (2008) (0)
Temporal Analysis of Steroidogenic Factor‐1 Binding to the human CYP17 Promoter: Roles of Ligand Binding, Coactivator Recruitment, and Phosphorylation (2006) (0)
p54nrb/NONO Regulates Glucocorticoid Production by Controlling the Capacity for cAMP Signaling (2013) (0)
PMA induces acid ceramidase degradation: a role for phosphorylation in controlling protein function (2011) (0)
Post Translational Modifications by PAK6 and CARM1 Regulate p54nrb Function (2008) (0)
NONO Regulates cAMP-dependent Glucocorticoid Production by Modulating 1 Phosphodiesterase mRNA Splicing and Degradation 2 3 4 (2015) (0)
Protein interaction and phosphorylation of diaphanous 1 regulate mitochondria movement in H295R human adrenocortical cells (2010) (0)
Genistein Regulates Ceramide Metabolism by Inducing Acid Ceramidase Expression in MCF‐7 Breast Cancer Cells (2010) (0)
ACTH/cAMP‐Stimulated Phosphorylation of Diaphanous 1 Regulates Mitochondrial Movement in H295R Human Adrenocortical Cells (2011) (0)

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Other Resources About Marion Sewer

en.wikipedia.org

What Schools Are Affiliated With Marion Sewer?

Marion Sewer is affiliated with the following schools:

Marion Sewer's Academic­Influence.com Rankings