Marjorie G. Horning

Marjorie G. Horning's AcademicInfluence.com Rankings

Marjorie G. Horning

Medical

#1592

World Rank

#1948

Historical Rank

#402

USA Rank

Pharmacology

#233

World Rank

#273

Historical Rank

#33

USA Rank

medical Degrees

Marjorie G. Horning

Biology

#6074

World Rank

#8707

Historical Rank

#2005

USA Rank

Biochemistry

#1296

World Rank

#1415

Historical Rank

#268

USA Rank

biology Degrees

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Medical
Biology

Marjorie G. Horning's Degrees

PhD Biochemistry University of California, Berkeley
Doctorate Pharmacology Stanford University

Why Is Marjorie G. Horning Influential?

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According to Wikipedia, Marjorie Janice Groothuis Horning was an American biochemist and pharmacologist. She was considered to be a pioneer of chromatography for her work in developing new techniques and applying them to the study of drug metabolism. She demonstrated that drugs and their metabolites can be transferred from a pregnant woman to her developing child, and later through breast milk, from a mother to a baby. Horning's work made possible the prevention of birth defects, as doctors began to warn of the dangers of drugs, alcohol, and smoking during pregnancy.

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Marjorie G. Horning's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

New picogram detection system based on a mass spectrometer with an external ionization source at atmospheric pressure (1973) (472)
Chemical ionization mass spectrometry. (1973) (310)
A gas-liquid-chromatographic procedure for separating a wide range of metabolites occuring in urine or tissue extracts. (1966) (292)
Metabolic profiles: gas-phase methods for analysis of metabolites. (1971) (229)
Use of saliva in therapeutic drug monitoring. (1977) (220)
Metabolism of carbamazepine. (1982) (185)
Infants exposed in utero to antiepileptic drugs. A prospective study. (1974) (185)
Subpicogram detection system for gas phase analysis based upon atmospheric pressure ionization (API) mass spectrometry (1974) (172)
Atmospheric pressure ionization (API) mass spectrometry. Solvent-mediated ionization of samples introduced in solution and in a liquid chromatograph effluent stream. (1974) (170)
Human Metabolic Profiles Obtained by GC and GC/MS (1971) (166)
Methone derivatives of aldehydes. (1946) (164)
Liquid chromatograph—mass spectrometer—computer analytical systems (1974) (155)
The GLC Separation of Hydroxyl-Substituted Amines of Biological Importance Including the Catecholamines. Preparation of Derivatives for Electron Capture Detection (1968) (107)
Fatty Acid Esterification with N,N-Dimethylformamide Dialkyl Acetals for GC Analysis (1972) (105)
The characterization by gas-liquid chromatography of ethyll beta-D-glucosiduronic acid as a metabolite of ethanol in rat and man. (1967) (97)
Separation of tissue cholesterol esters and triglycerides by silicic acid chromatography. (1960) (92)
Formation and gas-liquid chromatographic behavior of isometric steroid ketone methoxime derivatives. (1968) (89)
Drug metabolism in the human neonate. (1975) (86)
High resolution gas chromatography with thermostable glass open tubular capillary columns (1973) (84)
Drug metabolism and drug toxicity (1984) (83)
Studies of Analytical Separations of Human Steroids and Steroid Glucuronides (1967) (79)
Congenital lipoid adrenal hyperplasia in an eight-year-old phenotypic female. (1973) (68)
A new method for the separation of the catecholamines by gas-liquid chromatography. (1967) (67)
The Use of Gas Phase Analytical Methods For the Analysis of Phospholipids (1969) (67)
Elimination of antipyrine and benzo[a]pyrene metabolism in cultured human lymphocytes (1976) (67)
Gas chromatographic determination of polyols and aldoses in human urine as polyacetates and aldononitrile polyacetates. (1975) (55)
Nicotine in smokers, non-smokers and room air. (1973) (55)
Isolation of drugs and drug metabolites from biological fluids by use of salt-solvent pairs. (1974) (55)
Separation and characterization of the prostaglandins by gas chromatography and mass spectrometry. (1969) (54)
Analyses of phospholipids, ceramides, and cerebrosides by gas chromatography and gas chromatography-mass spectrometry. (1971) (52)
Derivatives for the characterization of alkyl- and aminoalkylphosphonates by gas chromatography and gas chromatography-mass spectrometry. (1973) (52)
Characterization of the trimethylsilyl derivatives of sugar phosphates and related compounds by gas chromatography and gas chromatography-mass spectrometry. (1973) (49)
Studies on the biosynthesis of cholesterol—7 : Rearrangement of methyl groups during enzymic cyclisation of squalene (1959) (49)
The metabolism of safrole and 2',3'-epoxysafrole in the rat and guinea pig. (1974) (49)
Gas-liquid chromatographic study and estimation of several urinary aromatic acids. (1966) (48)
Benzyloxime Derivatives of Steroids. A New Metabolic Profile Procedure for Human Urinary Steroids Human Urinary Steroids (1971) (47)
Profiles of volatile metabolites in body fluids (1976) (47)
The Study of Urinary Acids and Related Compounds by Gas Phase Analytical Methods (1967) (44)
Epoxide intermediates in the metabolism of naphthalene by the rat. (1980) (44)
Detection of 5-(3, 4-Dihydroxy-1, 5-Cyclohexadien-1-Yl) -5-Phenylsydantoin as a Major Metabolite of 5, 5-Diphenylhydantoin (Dilantin) in the Newborn Human (1971) (41)
The Collagen and Ground Substance of Human Intervertebral Disc at Different Ages. (1962) (40)
Gas phase analytical methods for the study of human metabolites. Metabolic profiles obtained by open tubular capillary chromatography. (1974) (40)
Part II. Tryptamine-Related Amines and Catecholamines. (1964) (38)
Metabolism of biphenyl in the rat. (1978) (36)
Correlation of aryl hydrocarbon hydroxylase activity of human lymphocyte cultures and plasma elimination rates for antipyrine and phenylbutazone. (1975) (36)
Use of stable isotopes in measuring low concentrations of drugs and drug metabolites by GC-MS-COM procedures. (1973) (36)
Characterization and estimation of urinary steroids of the newborn human by gas-phase analytical methods. (1969) (35)
O-benzyloximes: derivatives for the study of ketosteroids by gas chromatography. Application to urinary steroids of the newborn human. (1971) (33)
A rapid procedure for the isolation of drugs and drug metabolites from plasma. (1972) (32)
Aromatization Studies. IV. Palladium Dehydrogenation of Arylcyclohexenones to Phenols (1947) (31)
The Glc Separation of Indole Amines and Indole Alcohols as Heptafluorobutyryl Derivatives (1969) (28)
Anticonvulsant drug monitoring by GC-MS-COM techniques. (1974) (26)
Characterization of metabolites of steroid contraceptives by gas chromatography and mass spectrometry. (1972) (25)
ENZYMATIC DEGRADATION OF THE CHOLESTEROL SIDE CHAIN IN CELL-FREE PREPARATIONS (1953) (25)
Coumarins from 2-hydroxy-3-methoxybenzaldehyde. (1947) (25)
High-performance liquid chromatographic separation and isolation of quinidine and quinine metabolites in rat urine. (1980) (24)
Identification of new sulfur-containing metabolites of naphthalene in mouse urine. (1982) (24)
The use of stable isotopes in gas chromatography-mass spectrometric studies of drug metabolism. (1974) (24)
Clinical applications of gas chromatograph/mass spectrometer/computer systems. (1975) (24)
Metabolism of 2-ethyl-2-methylsuccinimide (ethosuximide) in the rat and human. (1973) (23)
Gas phase analytical separation and structural study of ceramides (1969) (23)
Some stereochemical factors in the formation of rearrangement ions in the mass spectra of trimethylsilyl derivatives of steroidal phosphates (1971) (22)
Detection of a 5-(3,4-dihydroxy-1,5-cyclohexadien-1-yl)-metabolite of phenobarbital and mephobarbital in rat, guinea pig and human. (1972) (21)
Variations in urinary steroid profiles after birth. (1971) (21)
Ion-Molecule Reaction Products Found in the Mass Spectra of Trimethylsilyl Derivatives (1970) (19)
An investigation of recurrent pine oil poisoning in an infant by the use of gas chromatographic-mass spectrometric methods. (1975) (19)
Overview of alkylation and peroxidation mechanisms in acute lethal hepatocellular injury by chemically reactive metabolites. (1981) (19)
Aromatization studies; alkylcarbazoles. (1948) (18)
Studies on the enzymatic degradation of the cholesterol side chain. II. Requirements of the mitochondrial system. (1957) (17)
A New Procedure for the Extraction of Unconjugated Steroids from Plasma and Urine (1973) (17)
Gas Chromatographic Study of Phosphatidyl Serines (1968) (17)
Gas chromatographic determination of aromatic acid metabolites of phenylalanine in brain. (1976) (16)
Urinary bivalent sulfur metabolites of phenanthrene excreted by the rat and guinea pig. (1982) (16)
Bromobenzene metabolism in the rat and guinea pig. (1987) (16)
Vapor phase bimolecular reactions of alkyl siliconium and other metal ions in mass spectrometry (1971) (16)
Comparative metabolism of four allylic barbiturates and hexobarbital by the rat and guinea pig. (1977) (16)
Metabolic profiles: chromatographic methods for isolation and characterization of a variety of metabolites in man. (1970) (16)
Aromatization Studies. VIII. Catalytic Dehydrogenation of Di- and Trialkylcyclohexenones to Phenols (1949) (15)
Metabolic switching of drug pathways as a consequence of deuterium substitution (1975) (15)
Detection by Gas Phase Analytical Methods of Derivatives of Barbiturate Epoxides (1972) (14)
Chemistry of anti- and syn-1,2:3,4-naphthalene dioxides and their potential relevance as metabolic intermediates (1982) (14)
Metabolite kinetics: formation of acetaminophen from deuterated and nondeuterated phenacetin and acetanilide on acetaminophen sulfation kinetics in the perfused rat liver preparation. (1982) (14)
Detection of epoxides of allyl-substituted barbiturates in rat urine. (1972) (13)
Drug metabolism and distribution (1983) (13)
Metabolism of methaqualone by the epoxide-diol pathway in man and the rat. (1975) (13)
Metabolism of styrene oxide in the rat and guinea pig. (1983) (13)
Gas phase analytical separation techniques applicable to problems in clinical chemistry. (1971) (13)
Isolation of a new bile acid, 3 ,7 ,12 -trihydroxy-5 -cholestan-26-oic acid, from lizard bile. (1972) (13)
Metabolism of N,2-dimethyl-2-phenylsuccinimide (methsuximide) by the epoxide-diol pathway in rat, guinea pig and human. (1973) (12)
Metabolism of antipyrine by the epoxide-diol pathway in the rat, guinea pig and human. (1974) (12)
The mass spectra of the trimethylsilyl derivatives of some alkyl and aminoalkyl phosphonates (1974) (12)
Analytical methods for the study of urinary thioether metabolites in the rat and guinea pig. (1987) (11)
The mass spectra of the trimethylsilyl derivatives of glycerophosphoric acids. Inter- and intra-molecular rearrangements of siliconium ions (1972) (11)
Characterization of the isomeric dialkylbarbituric acids formed by the reaction of barbiturates with diazoalkanes. (1974) (11)
AROMATIC ACID METABOLITES OF PHENYLALANINE IN THE BRAIN OF THE HYPERPHENYLALANINEMIC RAT: EFFECT OF PYRIDOXAMINE (1977) (11)
The intermolecular transfer of trimethylsilyl groups induced by electron impact (1970) (11)
Semimicrodetermination of Carbon and Hydrogen (1947) (11)
Urinary excretion of phenobarbital in a neonate having withdrawal symptoms. (1977) (10)
The use of gas chromatographic-mass spectrometric-computer systems in pharmacokinetic studies. (1975) (10)
Identification and quantification of drugs in human amniotic fluid. (1975) (10)
2579 – METHYLTHIO METABOLITES OF NAPHTHALENE EXCRETED BY THE RAT (1978) (10)
Dose-dependent kinetics of quinidine in the perfused rat liver preparation. Kinetics of formation of active metabolites. (1982) (9)
Ten Year Follow‐up of Paroxysmal Choreoathetosis: A Sporadic Case Becomes Familial (1978) (9)
Conversion of bromobenzene to 3-bromophenol. A route to 3- and 4-bromophenol through sulfur-series intermediates derived from the 3,4-oxide. (1987) (9)
The mass spectra of the trimethylsilyl esters of acetyl, schiff base and isothiocyanate derivatives of some aminoalkylphosphonic acids (1974) (8)
Isotope effects on pathways of metabolism (1978) (8)
Identification of metabolites of phenylacetic acid in rat brain by plasma desorption mass spectrometry. (1980) (8)
Identification and synthesis of the isomeric tetrahydroxytetrahydronaphthalene metabolites excreted in rat urine. (1982) (8)
The effect of 3-methylcholanthrene, Aroclor 1254, and phenobarbital induction on the metabolism of biphenyl by rat and mouse 9000g supernatant liver fractions. (1981) (7)
The effect of phenobarbital and beta-naphthoflavone induction on the metabolism of biphenyl in the rat and mouse. (1981) (7)
On the oxidation of cholesterol by mouse liver mitochondria. Bile acids and steroids 88. (1959) (7)
Analogs of Dihydroionone (1949) (7)
Synthesis and elimination reactions of methylsulfonium ions formed from styrene oxide and methylthio compounds related to methionine and cysteine. (1984) (6)
High-performance liquid chromatographic separation of carbamazepine metabolites excreted in rat urine. (1980) (6)
Pathways of formation of 2-, 3- and 4-bromophenol from bromobenzene. Proposed mechanism for C-S lyase reactions of cysteine conjugates. (1993) (6)
The use of gass chromatography-mass spectrometry methods in perinatal pharmacology. (1973) (5)
Metabolism of bromobenzene. Analytical chemical and structural problems associated with studies of the metabolism of a model aromatic compound. (1987) (5)
Morphine studies; 2-(2',3'-dimethoxyphenyl)-2-(beta-ethoxyethyl)-cyclohexanone. (1948) (5)
Drugs and Lipid transport (1964) (5)
Plasma Desorption Ionization Mass Spectra of Unconjugated Human Steroids (1979) (4)
Formation in vivo of deuterated methylthio metabolites of naphthalene from L-methionine (methyl-d--3). (1978) (4)
COLCHICINE. STRUCTURE OF WINDAUS' ANHYDRIDE1,2 (1950) (4)
Formation of methylthio metabolites of indene in the guinea pig and the rat. (1986) (4)
Influence of choline and methionine on phospholipide activity and total lipide content of livers of young white rats. (1946) (4)
Synthesis of 2,6-Dimethyl-2-p-isopropylphenyl-6-carbomethoxycyclohexanone (1950) (4)
The in-fluence of supplementary casein, cystine, and methionine on liver lipid content of adult rats. (1944) (3)
On the Oxidation of Cholesterol by Blood in vitro. Bile Acids and Steroids 119. (1962) (3)
Profiles of volatile metabolities in body fluids. (1976) (3)
Morphine studies; the phenanthrene unit. (1947) (3)
Metabolism of glutethimide (Doriden) by the epoxide-diol pathway in the rat and guinea pig. (1973) (3)
COLCHICINE. NATURE OF THE B-RING1,2 (1950) (3)
279. Quantification of plasma cortisol and urinary 6β-hydroxycortisol in mother-infant pairs (1974) (3)
CHAPTER 13 – THE STEROL REQUIREMENTS OF INSECTS AND OF PROTOZOA* (1958) (3)
Methylthio metabolites of naphthalen excreted by the rat. (1978) (3)
Border Town Bullies: The Bad Auto Deal and Subprime Lending Problem Among Navajo Nation Car Buyers (2016) (3)
Bile acids in bile. (1970) (3)
Aromatization Studies. V. Synthesis of Alkylanilines from Alkylcyclohexenones (1947) (3)
59. Identification in the Newborn Infant of Transplacentally Acquired Anticonvulsant Drugs and Drug Metabolites (1969) (2)
2240 – CHANGES IN CHEMICAL AND BIOLOGICAL PROPERTIES OF DRUGS DUE TO DEUTERIUM LABELLING (1978) (2)
Organic bases. (1970) (2)
The Characterization of Phospholipids by Gas Phase Analytical Methods (1969) (2)
Methods for the Study of Lipid Changes in Biological Experiments (1964) (2)
Plasma desorption ionization mass spectrometry — an introduction for pharmacologists (1979) (2)
Meetings Calendar (2003) (2)
MATERNAL DRUG INGESTION AND LACTATION (1974) (2)
Effects of ethylp-chlorophenoxyisobutyrate on biliary secretion of bile acids, cholesterol and phosphatidyl choline (1972) (2)
NEONATAL WITHDRAWAL FROM TRANSPLACENTALLY ACQUIRED MEPHOBARBITAL (1974) (1)
Analysis of drugs and their metabolites by gas chromatography-mass spectrometry-computer systems. (1978) (1)
Urinary acids. (1970) (1)
Use of stable isotopes in studies of drug metabolism (1973) (1)
Gas-Phase Analytical Methods. Mass Spectrometry and GC-MS-COM Analytical Systems (1974) (1)
Aromatization Studies. VI. Aminobiphenyls and Naphthylamines (1948) (1)
[Structural analysis of glycerophosphatides and sphingolipids with gas chromatography and mass spectrometry]. (1970) (1)
BIOCHEMICAL FACTORS IN CARBON TETRACHLORIDE TOXICITY (1965) (1)
Urinary steroids. (1970) (1)
Mass spectrometry of methylthio metabolites of aromatic hydrocarbons and related substances (1989) (1)
Analysis of Biologic Samples for Morphine and Morphine-Related Compounds by Gas Chromatographic-Mass Spectrometric Methods (1976) (0)
Use of Saliva in TherapeuticDrugMonitoring (2004) (0)
The synthesis of radioactive L-glutamic acid. (1954) (0)
104 – QUANTIFICATION OF ANTIEPILEPTIC DRUGS AND THEIR METABOLITES BY HIGH PERFORMANCE LIQUID CHROMATOGRAPHY (1978) (0)
Abstracts of papers Minneapolis Fall Meeting (1963) (0)
Metabolism of pronethalol in the rat, the guinea pig and the mouse. (1974) (0)
600 – RECYCLING OF DRUGS AND DRUG METABOLITES THROUGH MONOOXYGENASE SYSTEMS (1977) (0)
Urinary sugars and sugar alcohols. (1970) (0)
Phospholipids in bile. (1970) (0)
1401 – GC–MS STUDIES OF THE METABOLISM OF GLUTETHIMIDE ENANTIOMERS (1977) (0)
Useof SalivainTherapeutic DrugMonitoring (1977) (0)
1234 – PROLONGED EXCRETION OF BARBITURATES BY THE NEONATE (1977) (0)
[Urinary steroids in the new-born: characterization by gas chromatography and mass spectrometry of four androstenetetrols]. (1969) (0)
QUANTIFICATION OF PLASMA CORTISOL AND URINARY 6β-HYDROXYCORTISOL IN MOTHER-INFANT PAIRS (1974) (0)
1184 – CHANGES IN BIPHENYL METABOLISM IN RATS FOLLOWING INDUCTION WITH β-NAPHTHOFLAVONE AND PHENOBARBITAL. Karla Halpaap (1978) (0)
Drugs Affecting the Enterohepatic Circulation of Cholesterol (1969) (0)
Meetings calendar (2005) (0)
Meetings Calendar (2013) (0)
The Mechanism of a Rearrangement Occurring During Biosynthesis of Cholesterol (2009) (0)
291 – A COMPARISON OF THE IN VITRO AND IN VIVO METABOLISM OF SECOBARBITAL AND SECOBARBITAL EPOXIDE (1977) (0)
Gas-Phase Analytical Methods and Instruments (1972) (0)
Plasma acids. (1970) (0)
The effect of inducers on the profile of biphenyl metabolites formed in vitro. Abstr. (1979) (0)
Plasma sugars and sugar alcohols. (1970) (0)
1170 – EFFECT OF DEUTERIUM SUBSTITUTION ON THE METABOLISM OF CAFFEINE (1978) (0)

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