Mark Caulfield

Q: What Schools Are Affiliated With Mark Caulfield

Mark Caulfield is affiliated with the following schools: United States Military Academy, Lund University, Queen Mary University of London, Massachusetts General Hospital, University of Cambridge, Harvard University, University of Leicester, University of Lausanne

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According to Wikipedia, Sir Mark Jonathan Caulfield MD, FRCP, FESC, FPharm, FBHS, FMedSci is a British genomic medicine researcher and Warden of Barts and The London School of Medicine and Dentistry. He is the professor of Clinical Pharmacology at the William Harvey Research Institute in Queen Mary University of London. He was awarded a knighthood in the 2019 Birthday Honours.

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Mark Caulfield's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls (2007) (9208)
2013 ESH/ESC guidelines for the management of arterial hypertension: the Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). (2013) (6036)
Genetic studies of body mass index yield new insights for obesity biology (2015) (3549)
Biological, Clinical, and Population Relevance of 95 Loci for Blood Lipids (2010) (3485)
Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial—Lipid Lowering Arm (ASCOT-LLA): a multicentre randomised controlled trial (2003) (2437)
Effects of torcetrapib in patients at high risk for coronary events. (2007) (2393)
Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA): a multicentre randomised controlled tri (2005) (2151)
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index (2010) (2011)
Hundreds of variants clustered in genomic loci and biological pathways affect human height (2010) (1961)
Genetic Variants in Novel Pathways Influence Blood Pressure and Cardiovascular Disease Risk (2011) (1928)
Defining the role of common variation in the genomic and biological architecture of adult human height (2014) (1805)
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation (2009) (1735)
Reappraisal of European guidelines on hypertension management: a European Society of Hypertension Task Force document (2009) (1452)
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants (2007) (1421)
Common variants near MC4R are associated with fat mass, weight and risk of obesity (2008) (1307)
New genetic loci link adipose and insulin biology to body fat distribution (2014) (1227)
Genome-wide association study identifies eight loci associated with blood pressure (2009) (1225)
Association analyses of 249,796 individuals reveal eighteen new loci associated with body mass index (2010) (1179)
Blood pressure and incidence of twelve cardiovascular diseases: lifetime risks, healthy life-years lost, and age-specific associations in 1·25 million people (2014) (1159)
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility (2014) (933)
Prevention of Coronary and Stroke Events with Atorvastatin in Hypertensive Patients who have Average or Lower-than-Average Cholesterol Concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial— Lipid Lowering Arm (ASCOT-LLA): A Multicentre Randomised Controlled Trial (2012) (918)
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution (2010) (897)
Genetic mechanisms of critical illness in COVID-19 (2020) (887)
Genome-wide association analysis identifies 20 loci that influence adult height (2008) (816)
Spironolactone versus placebo, bisoprolol, and doxazosin to determine the optimal treatment for drug-resistant hypertension (PATHWAY-2): a randomised, double-blind, crossover trial (2015) (787)
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways (2012) (758)
Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries (2018) (735)
Modulation of Genetic Associations with Serum Urate Levels by Body-Mass-Index in Humans (2015) (724)
Reappraisal of European guidelines on hypertension management: a European Society of Hypertension Task Force document. (2009) (707)
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations (2012) (678)
Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits (2018) (659)
A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease (2011) (638)
Effects of torcetrapib in patients at high risk for coronary events (2008) (624)
Meta-Analysis of 28,141 Individuals Identifies Common Variants within Five New Loci That Influence Uric Acid Concentrations (2009) (617)
Meta-analysis and imputation refines the association of 15q25 with smoking quantity (2010) (605)
Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls (2010) (600)
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture (2013) (568)
Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma (2011) (526)
Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci (2011) (518)
Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution (2009) (516)
Genetic risk, coronary heart disease events, and the clinical benefit of statin therapy: an analysis of primary and secondary prevention trials (2015) (515)
Rare and low-frequency coding variants alter human adult height (2016) (511)
Management of hypertension: summary of NICE guidance (2011) (492)
Genome-wide association study of copy number variation in 16,000 cases of eight common diseases and 3,000 shared controls (2010) (465)
Mapping the human genetic architecture of COVID-19 (2021) (455)
Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia. (2008) (450)
Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk (2017) (428)
Exome-wide association study of plasma lipids in >300,000 individuals (2017) (428)
Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk (2017) (428)
Mutational signature in colorectal cancer caused by genotoxic pks+E. coli (2020) (426)
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure (2011) (424)
Bayesian refinement of association signals for 14 loci in 3 common diseases (2012) (416)
Concept, Design and Implementation of a Cardiovascular Gene-Centric 50 K SNP Array for Large-Scale Genomic Association Studies (2008) (416)
Reduction in cardiovascular events with atorvastatin in 2,532 patients with type 2 diabetes: Anglo-Scandinavian Cardiac Outcomes Trial--lipid-lowering arm (ASCOT-LLA). (2005) (400)
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function (2016) (388)
Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits (2013) (365)
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals (2016) (347)
Similarity of synthetic peptide from human tumor to parathyroid hormone in vivo and in vitro. (1987) (346)
Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction (2010) (345)
Dietary nitrate provides sustained blood pressure lowering in hypertensive patients: a randomized, phase 2, double-blind, placebo-controlled study. (2015) (344)
SLC2A9 Is a High-Capacity Urate Transporter in Humans (2008) (334)
Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120 (2013) (329)
Role of blood pressure and other variables in the differential cardiovascular event rates noted in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA) (2005) (325)
Cost-effectiveness of options for the diagnosis of high blood pressure in primary care: a modelling study (2011) (314)
Linkage of the angiotensinogen gene to essential hypertension. (1994) (305)
Lipoprotein(a) Concentrations, Rosuvastatin Therapy, and Residual Vascular Risk: An Analysis From the JUPITER Trial (Justification for the Use of Statins in Prevention An Intervention Trial Evaluating Rosuvastatin) (2013) (303)
Prediction of Susceptibility to First‐Line Tuberculosis Drugs by DNA Sequencing (2018) (295)
Genome-Wide Association Study of Blood Pressure Extremes Identifies Variant near UMOD Associated with Hypertension (2010) (285)
Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci. (2012) (282)
Rationale, design, methods and baseline demography of participants of the Anglo-Scandinavian Cardiac Outcomes Trial (2001) (271)
Genetic loci influencing kidney function and chronic kidney disease (2010) (266)
Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization (2014) (260)
Trans-ethnic association study of blood pressure determinants in over 750,000 individuals (2018) (249)
Greater risk of severe COVID-19 in Black, Asian and Minority Ethnic populations is not explained by cardiometabolic, socioeconomic or behavioural factors, or by 25(OH)-vitamin D status: study of 1326 cases from the UK Biobank (2020) (248)
Mutations in the TGF-β Repressor SKI Cause Shprintzen-Goldberg Syndrome with Aortic Aneurysm (2012) (241)
Causal Associations of Adiposity and Body Fat Distribution With Coronary Heart Disease, Stroke Subtypes, and Type 2 Diabetes Mellitus: A Mendelian Randomization Analysis (2017) (239)
Whole-genome sequencing of patients with rare diseases in a national health system (2020) (239)
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. (2012) (238)
Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension (2016) (234)
KLHL3 mutations cause familial hyperkalemic hypertension by impairing ion transport in the distal nephron (2012) (232)
Risk Profiles for Aortic Dissection and Ruptured or Surgically Treated Aneurysms: A Prospective Cohort Study (2015) (227)
Genetic and molecular aspects of hypertension. (2015) (221)
Genome-wide mapping of human loci for essential hypertension (2003) (214)
Differential effects of metformin and troglitazone on cardiovascular risk factors in patients with type 2 diabetes. (2002) (207)
Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins (2014) (207)
The 100 000 Genomes Project: bringing whole genome sequencing to the NHS (2018) (206)
Linkage of the angiotensinogen gene locus to human essential hypertension in African Caribbeans. (1995) (205)
Genome-wide scan identifies CDH13 as a novel susceptibility locus contributing to blood pressure determination in two European populations (2009) (201)
Genetic evidence of assortative mating in humans (2017) (199)
Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. (2009) (195)
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure underpinning obesity (2017) (193)
PanelApp crowdsources expert knowledge to establish consensus diagnostic gene panels (2019) (192)
Direct determination of lipoprotein particle sizes and concentrations by ion mobility analysis. (2008) (191)
A DNA variant at the angiotensin-converting enzyme gene locus associates with coronary artery disease in the Caerphilly Heart Study. (1995) (187)
Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study (2011) (185)
Association of Hypertension Drug Target Genes With Blood Pressure and Hypertension in 86 588 Individuals (2011) (178)
Blood pressure loci identified with a gene-centric array. (2011) (177)
Enhanced Vasodilator Activity of Nitrite in Hypertension: Critical Role for Erythrocytic Xanthine Oxidoreductase and Translational Potential (2013) (177)
Essential hypertension in African Caribbeans associates with a variant of the beta2-adrenoceptor. (1997) (172)
Genes for blood pressure: an opportunity to understand hypertension. (2013) (171)
Genomewide Association Study Using a High-Density Single Nucleotide Polymorphism Array and Case-Control Design Identifies a Novel Essential Hypertension Susceptibility Locus in the Promoter Region of Endothelial NO Synthase (2012) (163)
Functional analyses of coronary artery disease associated variation on chromosome 9p21 in vascular smooth muscle cells. (2012) (160)
Variants in the fetal genome near FLT1 are associated with risk of preeclampsia (2017) (159)
Potential synergy between lipid-lowering and blood-pressure-lowering in the Anglo-Scandinavian Cardiac Outcomes Trial. (2006) (154)
Endocrine and haemodynamic changes in resistant hypertension, and blood pressure responses to spironolactone or amiloride: the PATHWAY-2 mechanisms substudies (2018) (153)
The Trans-Ancestral Genomic Architecture of Glycemic Traits (2020) (151)
Ion Mobility Analysis of Lipoprotein Subfractions Identifies Three Independent Axes of Cardiovascular Risk (2009) (150)
Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci. (2014) (150)
Association of WNK1 Gene Polymorphisms and Haplotypes With Ambulatory Blood Pressure in the General Population (2005) (147)
Genome-wide association study of survival from sepsis due to pneumonia: an observational cohort study (2015) (146)
Loci influencing blood pressure identified using a cardiovascular gene-centric array. (2013) (145)
Directional dominance on stature and cognition in diverse human populations (2015) (144)
Inhibition of osteoclastic bone resorption in vivo by echistatin, an "arginyl-glycyl-aspartyl" (RGD)-containing protein. (1993) (139)
Common Variants in Genes Underlying Monogenic Hypertension and Hypotension and Blood Pressure in the General Population (2008) (136)
Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height. (2011) (133)
The power of genetic diversity in genome-wide association studies of lipids (2021) (129)
Causal association between periodontitis and hypertension: evidence from Mendelian randomization and a randomized controlled trial of non-surgical periodontal therapy (2019) (128)
Ambulatory blood pressure monitoring predicts cardiovascular events in treated hypertensive patients – an Anglo-Scandinavian cardiac outcomes trial substudy (2009) (127)
Endothelial C-type natriuretic peptide maintains vascular homeostasis. (2014) (126)
Validation of a total testosterone assay using high-turbulence liquid chromatography tandem mass spectrometry: Total and free testosterone reference ranges (2010) (122)
Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney (2017) (121)
Whole-genome sequencing reveals host factors underlying critical COVID-19 (2022) (120)
Regulation of glucose transport and insulin signaling by troglitazone or metformin in adipose tissue of type 2 diabetic subjects. (2002) (117)
Genetic Predisposition to High Blood Pressure and Lifestyle Factors: Associations With Midlife Blood Pressure Levels and Cardiovascular Events (2017) (116)
NICE hypertension guideline 2011: evidence based evolution (2012) (113)
Haplotypes of the WNK1 gene associate with blood pressure variation in a severely hypertensive population from the British Genetics of Hypertension study. (2005) (112)
Pseudoexon activation as a novel mechanism for disease resulting in atypical growth-hormone insensitivity. (2001) (110)
The diagnosis of congenital adrenal hyperplasia in the newborn by gas chromatography/mass spectrometry analysis of random urine specimens. (2002) (107)
Evaluation of the angiotensinogen locus in human essential hypertension: a European study. (1998) (106)
Targeting 160 Candidate Genes for Blood Pressure Regulation with a Genome-Wide Genotyping Array (2009) (106)
Common Variants in the ATP2B1 Gene Are Associated With Susceptibility to Hypertension: The Japanese Millennium Genome Project (2010) (105)
Advances in blood pressure genomics. (2013) (105)
Clinical whole-genome sequencing from routine formalin-fixed, paraffin-embedded specimens: pilot study for the 100,000 Genomes Project (2018) (105)
Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration (2011) (104)
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution (2011) (104)
The Anglo-Scandinavian Cardiac Outcomes Trial lipid lowering arm: extended observations 2 years after trial closure. (2008) (101)
The Anglo-Scandinavian Cardiac Outcomes Trial: blood pressure-lowering limb: effects in patients with type II diabetes (2008) (101)
The novel genetic variant predisposing to coronary artery disease in the region of the PSRC1 and CELSR2 genes on chromosome 1 associates with serum cholesterol (2008) (100)
A deleterious gene-by-environment interaction imposed by calcium channel blockers in Marfan syndrome (2015) (100)
A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure. (2018) (100)
ADAMTS7 cleavage and vascular smooth muscle cell migration is affected by a coronary-artery-disease-associated variant. (2013) (97)
Replication of the five novel loci for uric acid concentrations and potential mediating mechanisms. (2010) (94)
The 100,000 Genomes Project Protocol (2017) (93)
Predicting deleterious nsSNPs: an analysis of sequence and structural attributes (2006) (91)
Performance of Plasma Biomarkers and Diagnostic Panels for Nonalcoholic Steatohepatitis and Advanced Fibrosis in Patients With Type 2 Diabetes (2019) (91)
Eight blood pressure loci identified by genome-wide association study of 34,433 people of European ancestry (2009) (88)
The bovine renal parathyroid hormone (PTH) receptor has equal affinity for two different amino acid sequences: the receptor binding domains of PTH and PTH-related protein are located within the 14-34 region. (1990) (88)
A cross-sectional study of bone turnover markers in healthy premenopausal women. (2007) (87)
Quantitative insulin analysis using liquid chromatography-tandem mass spectrometry in a high-throughput clinical laboratory. (2013) (87)
GENOME WIDE ASSOCIATION STUDY OF BLOOD PRESSURE EXTREMES IDENTIFIES VARIANT IN UMOD ASSOCIATED WITH HYPERTENSION: 6B.01 (2010) (85)
KLHL3 mutations cause familial hyperkalemic hypertension by impairing ion transport in the distal nephron (2012) (84)
Phenotypic Characterization of EIF2AK4 Mutation Carriers in a Large Cohort of Patients Diagnosed Clinically With Pulmonary Arterial Hypertension (2017) (84)
Extracellular volume quantification in isolated hypertension - changes at the detectable limits? (2015) (84)
Cyclic parathyroid hormone related protein antagonists: lysine 13 to aspartic acid 17 [i to (i + 4)] side chain to side chain lactamization. (1991) (83)
Pre-clinical evaluation of a 15-valent pneumococcal conjugate vaccine (PCV15-CRM197) in an infant-rhesus monkey immunogenicity model. (2011) (80)
Effect of amiloride, or amiloride plus hydrochlorothiazide, versus hydrochlorothiazide on glucose tolerance and blood pressure (PATHWAY-3): a parallel-group, double-blind randomised phase 4 trial (2016) (80)
Ethnic differences in blood pressure response to first and second-line antihypertensive therapies in patients randomized in the ASCOT Trial. (2010) (79)
Causal Effect of Plasminogen Activator Inhibitor Type 1 on Coronary Heart Disease (2017) (78)
Atherogenic Lipoprotein Subfractions Determined by Ion Mobility and First Cardiovascular Events After Random Allocation to High-Intensity Statin or Placebo: The Justification for the Use of Statins in Prevention An Intervention Trial Evaluating Rosuvastatin (JUPITER) Trial (2015) (78)
DNA Sequencing Predicts 1st-Line Tuberculosis Drug Susceptibility Profiles (2018) (76)
Combination Therapy Is Superior to Sequential Monotherapy for the Initial Treatment of Hypertension: A Double‐Blind Randomized Controlled Trial (2017) (73)
Lipoprotein nature of Bacillus licheniformis membrane penicillinase. (1981) (73)
Removal of partial agonism from parathyroid hormone (PTH)-related protein-(7-34)NH2 by substitution of PTH amino acids at positions 10 and 11. (1990) (73)
Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci (2019) (72)
The 100,000 Genomes Pilot on Rare Disease Diagnosis in Healthcare − A Preliminary Report (2021) (72)
Genes and hypertension. (2003) (70)
Associations of autozygosity with a broad range of human phenotypes (2019) (68)
Common Genetic Variation Near the Phospholamban Gene Is Associated with Cardiac Repolarisation: Meta-Analysis of Three Genome-Wide Association Studies (2009) (67)
Genetic predisposition to hypertension is associated with preeclampsia in European and Central Asian women (2020) (67)
PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION (2018) (67)
A saturated map of common genetic variants associated with human height (2022) (65)
Effects of long-term averaging of quantitative blood pressure traits on the detection of genetic associations. (2014) (64)
Nuclear-mitochondrial DNA segments resemble paternally inherited mitochondrial DNA in humans (2020) (64)
Genome-wide mapping of human loci for essential hypertension ☆ (2003) (64)
Angiotensinogen in human essential hypertension. (1996) (63)
The 7-34-fragment of human hypercalcemia factor is a partial agonist/antagonist for parathyroid hormone-stimulated cAMP production. (1988) (62)
White Blood Cells and Blood Pressure A Mendelian Randomization Study (2020) (61)
Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data (2019) (61)
Pan-ancestry exome-wide association analyses of COVID-19 outcomes in 586,157 individuals (2021) (59)
Clinical Utility of Insulin-Like Growth Factor 1 and 2; Determination by High Resolution Mass Spectrometry (2012) (59)
Two-dimensional genome-scan identifies novel epistatic loci for essential hypertension. (2006) (57)
Genetics of essential hypertension. (2004) (57)
Suckling-mediated increases in urinary phosphate and 3',5'-cyclic adenosine monophosphate excretion in lactating rats: possible systemic effects of parathyroid hormone-related protein. (1991) (55)
Atherogenic Lipoprotein Subfractions Determined by Ion Mobility and First Cardiovascular Events After Random Allocation to High-Intensity Statin or Placebo: The JUPITER Trial (2015) (54)
Genome-wide association study of genetic determinants of LDL-c response to atorvastatin therapy: importance of Lp(a) [S] (2012) (54)
Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals (2020) (53)
Polymorphisms in the WNK1 Gene Are Associated with Blood Pressure Variation and Urinary Potassium Excretion (2009) (52)
A systematic CRISPR screen defines mutational mechanisms underpinning signatures caused by replication errors and endogenous DNA damage (2021) (51)
A new highly potent parathyroid hormone antagonist: [D-Trp12,Tyr34]bPTH-(7-34)NH2. (1988) (51)
Population Genomics of Cardiometabolic Traits: Design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consortium (2013) (50)
New Blood Pressure–Associated Loci Identified in Meta-Analyses of 475 000 Individuals (2017) (50)
A blood pressure-associated variant of the SLC39A8 gene influences cellular cadmium accumulation and toxicity (2016) (48)
Joint UK societies’ 2014 consensus statement on renal denervation for resistant hypertension (2014) (46)
Concentrations of parathyroid hormone-related protein in rat milk change with duration of lactation and interval from previous suckling, but not with milk calcium. (1992) (46)
Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use (2019) (45)
Testosterone reference ranges in normally cycling healthy premenopausal women. (2011) (45)
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (2019) (45)
White Blood Cells and Blood Pressure (2020) (44)
Coronary-Heart-Disease-Associated Genetic Variant at the COL4A1/COL4A2 Locus Affects COL4A1/COL4A2 Expression, Vascular Cell Survival, Atherosclerotic Plaque Stability and Risk of Myocardial Infarction (2016) (44)
Comprehensive Cancer-Predisposition Gene Testing in an Adult Multiple Primary Tumor Series Shows a Broad Range of Deleterious Variants and Atypical Tumor Phenotypes (2018) (43)
Large exopenicillinase, initial extracellular form detected in cultures of Bacillus licheniformis. (1980) (41)
Relationship between insulin resistance and amino acids in women and men (2015) (41)
Pathogenic Huntingtin Repeat Expansions in Patients with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis (2020) (40)
Chromosome 2p Shows Significant Linkage to Antihypertensive Response in the British Genetics of Hypertension Study (2006) (40)
Low circulating 25-hydroxyvitamin D concentrations are associated with defects in insulin action and insulin secretion in persons with prediabetes. (2015) (39)
Correction: Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution (2009) (39)
Glutathione S-transferase variants and hypertension (2008) (39)
Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction (2019) (38)
Performance of the SteatoTest, ActiTest, NashTest and FibroTest in a multiethnic cohort of patients with type 2 diabetes mellitus (2018) (38)
Polymorphic Variation in the 11β-Hydroxylase Gene Associates With Reduced 11-Hydroxylase Efficiency (2007) (37)
LDL subfractions are associated with incident cardiovascular disease in the Malmö Prevention Project Study. (2017) (36)
Export of extracellular levansucrase by Bacillus subtilis: inhibition by cerulenin and quinacrine (1979) (36)
Anglo-Scandinavian Cardiac Outcomes Trial: a brief history, rationale and outline protocol (2001) (35)
Tumor necrosis factor and interleukin 1 inhibit parathyroid hormone‐responsive adenylate cyclase in clonal osteoblast‐like cell by down‐regulating parathyroid hormone receptors (1992) (34)
Impact of amlodipine-based therapy among older and younger patients in the Anglo-Scandinavian Cardiac Outcomes Trial−Blood Pressure Lowering Arm (ASCOT-BPLA) (2011) (34)
A randomized, double blind, placebo‐controlled pilot trial of the safety and efficacy of atorvastatin in children with elevated low‐density lipoprotein cholesterol (LDL‐C) and type 1 diabetes (2015) (33)
Human Chromosome 17 in Essential Hypertension (2003) (33)
Use of a metabolomic approach to non‐invasively diagnose non‐alcoholic fatty liver disease in patients with type 2 diabetes mellitus (2018) (31)
Meta-analysis of genome-wide association studies of HDL cholesterol response to statins (2016) (31)
Renal artery sympathetic denervation: observations from the UK experience (2016) (30)
Common Polymorphisms in the CYP11B1 and CYP11B2 Genes: Evidence for a Digenic Influence on Hypertension (2013) (29)
Demonstration of post-translational secretion of human placental lactogen by a mammalian in vitro translation system. (1986) (29)
Discovery of novel heart rate-associated loci using the Exome Chip (2017) (29)
Linkage analysis using co-phenotypes in the BRIGHT study reveals novel potential susceptibility loci for hypertension. (2006) (28)
Possible association but no linkage of the HSD11B2 gene encoding the kidney isozyme of 11β‐hydroxysteroid dehydrogenase to hypertension in Black people (2001) (28)
A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure. (2019) (28)
Treatment of bone-derived ROS 17/2.8 cells with dexamethasone and pertussis toxin enables detection of partial agonist activity for parathyroid hormone antagonists. (1990) (28)
Novel polymorphic AluYb8 insertion in the WNK1 gene is associated with blood pressure variation in Europeans (2011) (28)
Phenotypic consequences of variation across the aldosterone synthase and 11‐beta hydroxylase locus in a hypertensive cohort: data from the MRC BRIGHT Study (2007) (28)
Increased Support for Linkage of a Novel Locus on Chromosome 5q13 for Essential Hypertension in the British Genetics of Hypertension Study (2006) (28)
A first update on mapping the human genetic architecture of COVID-19 (2022) (27)
The 64-kilodalton membrane protein of Bacillus subtilis is also present as a multiprotein complex on membrane-free ribosomes. (1984) (27)
Response to letter regarding article, "lipoprotein(a) concentrations, rosuvastatin therapy, and residual vascular risk: an analysis from the JUPITER trial (justification for the use of statins in prevention: an intervention trial evaluating rosuvastatin)". (2014) (26)
Genome-Wide Analysis of Blood Pressure Variability and Ischemic Stroke (2013) (26)
DYNC2H1 hypomorphic or retina-predominant variants cause nonsyndromic retinal degeneration (2020) (26)
De Novo Truncating Mutations in WASF1 Cause Intellectual Disability with Seizures (2018) (26)
Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits (2019) (26)
The Deep Genome Project (2020) (25)
Exploring hypertension genome‐wide association studies findings and impact on pathophysiology, pathways, and pharmacogenetics (2015) (25)
Increased NBCn1 expression, Na+/HCO3− co-transport and intracellular pH in human vascular smooth muscle cells with a risk allele for hypertension (2017) (25)
Parathyroid hormone-receptor interactions (1990) (24)
Comparability of Lipoprotein Particle Number Concentrations Across ES-DMA, NMR, LC-MS/MS, Immunonephelometry, and VAP: In Search of a Candidate Reference Measurement Procedure for apoB and non-HDL-P Standardization. (2018) (24)
Uncovering genetic mechanisms of hypertension through multi-omic analysis of the kidney (2021) (24)
Impact of atorvastatin among older and younger patients in the Anglo-Scandinavian Cardiac Outcomes Trial Lipid-Lowering Arm (2011) (24)
Over 1,000 genetic loci influencing blood pressure with multiple systems and tissues implicated. (2019) (24)
Haplotypes of the β2-adrenergic receptor gene are associated with essential hypertension in a Singaporean Chinese population (2004) (23)
Absence of linkage of the epithelial sodium channel to hypertension in black Caribbeans. (1998) (23)
The inhibition of Staphylococcus aureus enterotoxin a production by cerulenin and quinacrine; presumptive evidence for a lipid intermediate/protease release mechanism (1978) (22)
Novel lipoprotein subfraction and size measurements in prediction of mortality in maintenance hemodialysis patients. (2011) (22)
Whole genome sequencing for the diagnosis of neurological repeat expansion disorders in the UK: a retrospective diagnostic accuracy and prospective clinical validation study (2022) (22)
Effects of Calcium, Magnesium, and Potassium Concentrations on Ventricular Repolarization in Unselected Individuals. (2019) (22)
Genetics of hypertension. Therapeutic implications. (1998) (21)
Synthesis of fully active biotinylated analogues of parathyroid hormone and parathyroid hormone-related protein as tools for the characterization of parathyroid hormone receptors. (1992) (21)
Design, synthesis and utility of novel benzophenone-containing calcitonin analogs for photoaffinity labeling the calcitonin receptor. (1997) (21)
Scaling national and international improvement in virtual gene panel curation via a collaborative approach to discordance resolution. (2021) (20)
Hypertension genomics and cardiovascular prevention. (2018) (20)
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (2017) (20)
Use of whole genome sequencing to determine genetic basis of suspected mitochondrial disorders: cohort study (2021) (20)
Classification of LDL Phenotypes by 4 Methods of Determining Lipoprotein Particle Size (2013) (20)
The biological impact of blood pressure-associated genetic variants in the natriuretic peptide receptor C gene on human vascular smooth muscle (2017) (19)
Comparison of methods to identify individuals at increased risk of coronary disease from the general population (2003) (18)
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Correction: Corrigendum: Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk (2017) (18)
Greater risk of severe COVID-19 in non-White ethnicities is not explained by cardiometabolic, socioeconomic, or behavioural factors, or by 25(OH)-vitamin D status: study of 1,326 cases from the UK Biobank (2020) (18)
Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits (2018) (17)
Ethnic variations in lipid-lowering in response to a statin (EVIREST): a substudy of the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT). (2011) (17)
Analysis with the exome array identifies multiple new independent variants in lipid loci. (2016) (17)
Genetic association analysis of inositol polyphosphate phosphatase-like 1 (INPPL1, SHIP2) variants with essential hypertension (2007) (17)
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Nuclear-embedded mitochondrial DNA sequences in 66,083 human genomes (2022) (16)
Haplotypes of the beta-2 adrenergic receptor associate with high diastolic blood pressure in the Caerphilly prospective study (2006) (16)
Secretory S complex of Bacillus subtilis forms a large, organized structure when released from ribosomes. (1985) (15)
Relationship among 25-hydroxyvitamin D concentrations, insulin action, and cardiovascular disease risk in patients with essential hypertension. (2015) (15)
The genetic architecture of blood pressure variation (2009) (15)
Dissociation of cAMP accumulation and phosphate uptake in opossum kidney (OK) cells with parathyroid hormone (PTH) and parathyroid hormone related protein (PTHrP) (1990) (15)
Synthetic substrate for eukaryotic signal peptidase. Cleavage of a synthetic peptide analog of the precursor region of preproparathyroid hormone. (1989) (15)
Genetic analysis of over one million people identifies 535 novel loci for blood pressure (2017) (14)
Prevention And Treatment of Hypertension With Algorithm-based therapy (PATHWAY) number 2: protocol for a randomised crossover trial to determine optimal treatment for drug-resistant hypertension (2015) (14)
Group IIA Secretory Phospholipase A2, Vascular Inflammation, and Incident Cardiovascular Disease. (2019) (14)
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Effects of hydrophobic substitutions at position 18 on the potency of parathyroid hormone antagonists. (2009) (14)
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Erratum: Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects (2017) (14)
An ancestral 10-bp repeat expansion in VWA1 causes recessive hereditary motor neuropathy (2021) (14)
Abstract 10170: Lipoprotein(a) Concentrations, Rosuvastatin Therapy, and Residual Vascular Risk: An Analysis From the JUPITER Trial (2013) (14)
Lipoprotein subfractions by ion mobility in lean and obese children. (2012) (14)
Identification and validation of a novel pathogenic variant in GDF2 (BMP9) responsible for hereditary hemorrhagic telangiectasia and pulmonary arteriovenous malformations (2021) (13)
A genetic risk score is associated with statin-induced low-density lipoprotein cholesterol lowering. (2016) (13)
Synthetic signal peptide and analogs display different activities in mammalian and plant in vitro secretion systems. (1987) (13)
Pharmacogenomics in the UK National Health Service: opportunities and challenges. (2020) (13)
Association of penicillin-binding proteins and other enzymes with the ribosome-free membrane fraction of Bacillus subtilis (1983) (13)
Common Polymorphisms at the CYP17A1 Locus Associate With Steroid Phenotype: Support for Blood Pressure Genome-Wide Association Study Signals at This Locus. (2016) (13)
Biochemical markers of bone turnover and their utility in osteoporosis. (2004) (13)
Protein binding of indomethacin, methotrexate and morphine in patients with cancer. (1992) (13)
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Acute thrombocytopenia in patients treated with amiodarone is caused by antibodies specific for platelet membrane glycoproteins (2013) (11)
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Renal and adrenal adenosine 3',5'-monophosphate production and corticosteroid secretion in response to synthetic chicken parathyroid hormone-(1-34). (1989) (11)
Phospholemman Phosphorylation Regulates Vascular Tone, Blood Pressure, and Hypertension in Mice and Humans (2020) (11)
Multiple genetic variants explain measurable variance in type 2 diabetes-related traits in Pakistanis (2012) (11)
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Monotherapy versus dual therapy for the initial treatment of hypertension (PATHWAY-1): a randomised double-blind controlled trial (2015) (10)
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Modernising Medical Careers, Medical Training Application Service, and the Postgraduate Medical Education and Training Board: time for the emperors to don their clothes (2007) (10)
A catalog of associations between rare coding variants and COVID-19 outcomes (2020) (10)
Predicting Coronary Risk in the General Population — Is it Necessary to Measure High-Density Lipoprotein Cholesterol? (2003) (10)
Information capture using SNPs from HapMap and whole-genome chips differs in a sample of inflammatory and cardiovascular gene-centric regions from genome-wide estimates. (2007) (10)
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (2018) (10)
Solid‐phase synthesis and biologic activity of human parathyroid hormone(1–84) (1991) (9)
Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci (2020) (9)
Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation (2019) (9)
Evaluating the performance of a clinical genome sequencing program for diagnosis of rare genetic disease, seen through the lens of craniosynostosis (2021) (9)
Low-Density Lipoprotein Particle Number Is Associated With Cardiovascular Events Among Those Not Classified Into Statin Benefit Groups. (2015) (9)
Differences between disease‐associated endoplasmic reticulum aminopeptidase 1 (ERAP1) isoforms in cellular expression, interactions with tumour necrosis factor receptor 1 (TNF‐R1) and regulation by cytokines (2015) (9)
Genomic medicine: time for health-care transformation (2019) (9)
Controversies Surrounding Renal Denervation: Lessons Learned From Real‐World Experience in Two United Kingdom Centers (2016) (9)
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Testing the role of predicted gene knockouts in human anthropometric trait variation (2016) (8)
Influence of matrix metalloproteinase-12 on fibrinogen level. (2012) (8)
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Comparison of single and combination diuretics on glucose tolerance (PATHWAY-3): protocol for a randomised double-blind trial in patients with essential hypertension (2015) (8)
The Anglo-Scandinavian Cardiac Outcomes Trial: Blood pressure-lowering limb (ASCOT-BPLA): effects in patients with type 2 diabetes (2006) (8)
The synthetic precursor specific region of pre-pro-parathyroid hormone forms ion channels in lipid bilayers (1988) (8)
A novel, mild, specific and indirect maleimido-based radioiodolabeling method. Radiolabeling of analogs derived from parathyroid hormone (PTH) and PTH-related protein (PTHrP). (2009) (8)
Mendelian randomisation analyses find pulmonary factors mediate the effect of height on coronary artery disease (2019) (8)
Rapid diagnosis of testicular choriocarcinoma by urinary pregnancy tests (1990) (7)
Whole genome sequencing for diagnosis of neurological repeat expansion disorders (2020) (7)
Genetics of Hypertension (1998) (7)
Bile Acid Concentration Reference Ranges in a Pregnant Latina Population (2012) (7)
The Measurement of 3-Epimer 25-Hydroxyvitamin D by Mass Spectrometry in Clinical Specimens Detects Inconsequential Levels in Adult Subjects (2014) (7)
Association of cardiovascular events and lipoprotein particle size: Development of a risk score based on functional data analysis (2019) (7)
Randomised, double-blind, placebo-controlled study investigating the effects of inorganic nitrate on vascular function, platelet reactivity and restenosis in stable angina: protocol of the NITRATE-OCT study (2016) (6)
Random glucose GWAS in 493,036 individuals provides insights into diabetes pathophysiology, complications and treatment stratification (2021) (6)
Publisher Correction: Extensive identification of genes involved in congenital and structural heart disorders and cardiomyopathy (2022) (6)
Erratum: Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci (American Journal of Human Genetics (2012) 90 (410-425)) (2012) (6)
Progress in Determining the Genes for Hypertension, Insulin Resistance, and Dyslipidemia a (1997) (6)
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Automatic on-line extraction coupled with electrochemical detection as an improved method for the HPLC co-analysis of codeine and morphine in plasma and gastric juice. (1990) (6)
GENETIC ANALYSIS OF OVER ONE MILLION PEOPLE IDENTIFIES 535 NOVEL LOCI ASSOCIATED WITH BLOOD PRESSURE AND RISK OF CARDIOVASCULAR DISEASE (2018) (5)
Selection of candidate genes in hypertension. (2005) (5)
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Detection of Insulin-Like Growth Factor 1 Variants by Mass Spectrometry: Results from a Clinical Reference Laboratory. (2019) (5)
The Role of Pharmacogenomics in Contemporary Cardiovascular Therapy: A position statement from the European Society of Cardiology Working Group on Cardiovascular Pharmacotherapy. (2021) (5)
SOX11 variants cause a neurodevelopmental disorder with infrequent ocular malformations and hypogonadotropic hypogonadism and with distinct DNA methylation profile. (2022) (5)
Genetic variants in PPARGC1B and CNTN4 are associated with thromboxane A2 formation and with cardiovascular event free survival in the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT). (2018) (5)
An Academic Clinician's Road Map to Hypertension Genomics: Recent Advances and Future Directions MMXX. (2021) (5)
Global sequence properties for superfamily prediction: a machine learning approach (2009) (5)
Heteroplasmic mitochondrial DNA variants in cardiovascular diseases (2022) (5)
Parathyroid hormone-related protein (PTHrP): studies with synthetic peptides indicate that parathyroid hormone and PTHrP interact with the same receptor. (1990) (5)
A Tumor‐Secreted Protein Associated with Human Hypercalcemia of Malignancy (1988) (5)
Ethnic variations in response to a statin (EVIREST) (2001) (5)
Chromosome 1p shows significant linkage to steroid metabolism in hypertension in the British Genetics of Hypertension Study (2006) (5)
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Indomethacin and Protein Binding of Methotrexate (1992) (4)
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A chemically synthesized radiolabeled signal peptide: design, preparation, and biological evaluation of an iodinated analog of preproparathyroid hormone. (1988) (4)
Medical training in the UK: sleepwalking to disaster (2007) (4)
Erratum: Differential effects of metformin and troglitazone on cardiovascular risk factors in patients with type 2 diabetes (Diabetes Care (2002) 25 (542-549)) (2002) (4)
The genetic basis of hypertension: progress and opportunities. (1998) (4)
Ambulatory blood pressure monitoring and 24-h blood pressure control as predictors of outcome in treated hypertensive patients (2001) (4)
Use of low density lipoprotein particle number levels as an aid in statin treatment decisions for intermediate risk patients: a cost-effectiveness analysis (2016) (4)
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (2018) (4)
Whole-genome sequencing of chronic lymphocytic leukemia identifies subgroups with distinct biological and clinical features (2022) (4)
Efficacy and safety of azilsartan medoxomil/chlortalidone fixed‐dose combination in hypertensive patients uncontrolled on azilsartan medoxomil alone: A randomized trial (2018) (3)
Supplementary Material 5 (2014) (3)
100,000 genomes project: Integrating whole genome sequencing (WGS) data into clinical practice (2019) (3)
Supplementary Material 7 (2014) (3)
New Directions for the Design of Parathyroid Hormone Antagonists (1989) (3)
Supplementary Material 6 (2014) (3)
Debrisoquine-type genetic polymorphism differences in medifoxamine pharmacokinetics (1990) (3)
Chromosome 2p Shows Genome Wide Significant Linkage to Anti-Hypertensive Medication Response in the British Genetics of Hypertension (BRIGHT) Study.: LB57 (2005) (3)
Hypertension due to a deoxycorticosterone-secreting adrenal tumour diagnosed during pregnancy (2019) (3)
Causal Associations of Adiposity and Body Fat Distribution With Coronary Heart Disease, Stroke Subtypes, and Type 2 Diabetes MellitusClinical Perspective (2017) (3)
Genes for hypertension (2002) (3)
Preclinical evaluation of a 15-valent pneumococcal polysaccharide-protein conjugate vaccine in infant rhesus monkeys (52.20) (2010) (3)
Atheromatous vascular disease and ischaemic stroke in the UK. (2009) (3)
Adverse Cardiovascular Outcomes and Antihypertensive Treatment: A Genome‐Wide Interaction Meta‐Analysis in the International Consortium for Antihypertensive Pharmacogenomics Studies (2021) (3)
GUIDELINES Management of hypertension: summary of NICE guidance (2011) (3)
Common Polymorphisms at the CYP17A1 Locus Associate With Steroid PhenotypeNovelty and Significance (2016) (3)
Supplementary Material 3 (2015) (3)
Urinary albumin excretion in hypertensive siblings in the British Genetics of Hypertension study (2007) (3)
The MRC British Genetics of Hypertension Study - Genome-wide screen results (2002) (3)
A new tool for checks of data precision within the MRC British genetics of hypertension study (2000) (2)
First highly potent cyclic parathyroid hormone-related peptide (PTHrP) antagonist (1991) (2)
Association between Variants of the Human GSTM Gene Family and Hypertension: 8 (2006) (2)
Investigation of the epithelial sodium channel (hENaC) as a candidate gene for essential hypertension (EH) in African Caribbeans (1997) (2)
YIA3: ADAMTS7 CLEAVAGE AND VASCULAR SMOOTH MUSCLE CELL MIGRATION IS AFFECTED BY A CORONARY ARTERY DISEASE ASSOCIATED VARIANT (2013) (2)
Combining Protein-Protein Interaction (PPI) Network and Sequence Attributes for Predicting Hypertension Related Proteins (2008) (2)
Genetic association analysis of inositol polyphosphate phosphatase-like 1 (INPPL1, SHIP2) variants with essential (2007) (2)
Novel blood pressure locus and gene discovery using GWAS and expression datasets from blood and the kidney (2017) (2)
Chapter 36 – Monogenic Forms of Human Hypertension (2007) (2)
Hypertension and the roles of the 9p21.3 risk locus: Classic findings and new association data (2020) (2)
Correlation of secondary structure with biological activity for a leader peptide: circular dichroism-derived structure and in vitro biological activities of preproparathyroid hormone peptide and its analogs. (1991) (2)
Identifying High-Risk CLL to Predict Early Relapse after FCR Based Treatment Using Whole Genome Sequencing: First Results from the Genomics England CLL Pilot (2016) (2)
Novel GDF2 Loss of Function Variant in a Family with HHT and PAVMs Expands the Phenotype Associated with BMP9 Dysfunction (2020) (1)
LBOS 02-04 BLOOD PRESSURE-ASSOCIATED POLYMORPHISMS IN SLC4A7 (SODIUM/BICARBONATE CO-TRANSPORTER NBCn1) ARE LINKED TO GENE EXPRESSION AND INTRACELLULAR pH REGULATION. (2016) (1)
Pharmacogenetics: focus on pharmacodynamics (2001) (1)
3 – Synthesis and Synthetic Manipulations of Peptides Derived from Parathyroid Hormone and Parathyroid Hormone-Related Protein (1993) (1)
Status and future of genomics in blood pressure (2017) (1)
No Association of the Wnk1 Gene With Essential Hypertension in the Mrc Bright Study (2004) (1)
Loci influencing blood pressure identified using a cardiovascular gene-centric array (Correction to Ganesh et al. 22 (8): 1663) (2013) (1)
ENHANCED SUPPORT FOR LINKAGE TO CHROMOSOME 5Q13.1 AND HYPERTENSION IN THE BRITISH GENETICS OF HYPERTENSION (BRIGHT) STUDY.: 5.1 (2005) (1)
Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals (2020) (1)
Mendelian gene identification through mouse embryo viability screening (2022) (1)
No support for linkage of chromosome 17(q21-24) to Essential Hypertension in the MRC British Genetics of Hypertension (MRC BRIGHT) Study. (2001) (1)
Author Correction: Nuclear-mitochondrial DNA segments resemble paternally inherited mitochondrial DNA in humans (2020) (1)
Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution (2019) (1)
Supplementary Material 15 (2013) (1)
Analysis of the angiotensinogen gene in the MRC British genetics of Hypertension study. (2015) (1)
Protein interaction networks associated with cardiovascular disease and cancer: exploring the effect of bias on shared network properties (2014) (1)
6 Translating genomics for clinical benefit (2019) (1)
High glucose and low lactate: a metabolic signature of hypertension in human serum? (2008) (1)
Supplementary Material 9 (2013) (1)
Synthase Hypertension Susceptibility Locus in the Promoter Region of Endothelial NO Polymorphism Array and Case-Control Design Identifies a Novel Essential Genomewide Association Study Using a High-Density Single Nucleotide (2011) (1)
Development and Characterization of Monoclonal Antibodies to Staphylococcus aureus Capsule Type 5 (2008) (1)
Supplementary Material 4 (2015) (1)
Home Blood Pressure Monitoring: New Evidence for an Expanded Role (2014) (1)
Plasma Omega-3 Fatty Acid Distribution in a U.S. Population (2013) (1)
Correction: Population Genomics of Cardiometabolic Traits: Design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consortium (2013) (1)
Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits (2019) (1)
Protein binding of certain drugs in cancer (1991) (1)
2 Linkage of the angiotensinogen gene to human essential hypertension in African Caribbeans (1994) (1)
S66 Delivering the 100,000 genomes project to establish the functional role of DNA sequence variants in respiratory rare diseases (2019) (1)
The Pharmacogenetics of Statin Therapy on Clinical Events: No Evidence that Genetic Variation Affects Statin Response on Myocardial Infarction (2022) (1)
Labile Hypertension Responding to Testosterone Withdrawal (2013) (1)
LBOS 02-04 BLOOD PRESSURE-ASSOCIATED POLYMORPHISMS IN SLC4A7 (SODIUM/BICARBONATE CO-TRANSPORTER NBCn1) ARE LINKED TO GENE EXPRESSION AND INTRACELLULAR pH REGULATION (2016) (1)
Challenges in Cardiovascular Pharmacogenomics Implementation: A viewpoint from the European Society of Cardiology Working Group on Cardiovascular Pharmacotherapy. (2021) (1)
The Barts Health NHS Trust COVID-19 cohort: characteristics, outcomes and risk scoring of patients in East London. (2021) (1)
Trans-ethnic association study of blood pressure determinants in over 750,000 individuals (2018) (1)
Title : Polymorphisms in the WNK 1 Gene Are Associated with Blood Pressure Variation and Urinary Potassium Excretion (2009) (1)
Erratum: Meta-analysis of dense genecentric association studies reveals common and uncommon variants associated with height ((The American Journal of Human Genetics (2010) 88 (6-18)) (2012) (1)
Effect of Variation at the Aldosterone Synthase Locus (CYP11B2) on Adrenal 11-beta hydroxylation: Pilot Data from the MRC BRIGHT Study (2004) (1)
Gene therapy : the possibilities and the problems : Gene research and gene therapy (1998) (0)
The role of glycaemic, lipid, blood pressure and obesity risk factors as mediators of the effect of height on Coronary Artery Disease and Type 2 Diabetes Mellitus: A Mendelian Randomisation Study (2018) (0)
Abstract P048: Blood-Pressure Associated Variants in Natriuretic Peptide Receptor C Affect Human Vascular Smooth Muscle Cells Proliferation and Calcium Flux in Response to Angiotensin II (2015) (0)
P-334: Gender differences in carotid sinus baroreceptor reflexes in healthy young normal subjects and in ASCOT patients with treated essential hypertension (2002) (0)
Xanthine Oxidoreductase and Translational Potential Enhanced Vasodilator Activity of Nitrite in Hypertension : Critical Role for Erythrocytic (2013) (0)
Abstract 434: 100,000 Genomes Project: Cancer program (2018) (0)
Discovery of novel genes for serum urate and low-density lipoprotein cholesterol - Two biomarkers of cardiovascular disease (2007) (0)
Tiagabinindeholdende pharmaceutical compositions with controlled release (1998) (0)
HYDROGEN BONDING IN HYDROXYL-SUBSTITUTED ANTHRAQUINONES (1961) (0)
Tiagabinhaltige medicinal preparations with controlled drug for administration (1998) (0)
pharmaceutical controlled release compositions containing tiagabine that. (1998) (0)
The Deep Genome Project (2020) (0)
PanelApp crowdsources expert knowledge to establish consensus diagnostic gene panels (2019) (0)
Pharmacogenetic Meta-Analysis of Response to Antihypertensive Drugs within ASCOT (2015) (0)
A case for research consortia to accelerate vaccine candidate discovery: identification of a stable antigenic HIV-1 Clade A Env candidate (P6370) (2013) (0)
Genome-Wide Analysis of Blood Pressure Variability and Ischemic Stroke Clinical Sciences (2013) (0)
Pharmacogenetic GWAS meta-analysis of response to antihypertensive drugs (2015) (0)
Replicated association of regions at CYP11B1/B2 locus with hypertension in Caucasians (2010) (0)
Association of the ACE I/D polymorphism with CAD in a Welsh population (1994) (0)
University of Groningen Common Genetic Variation Near the Phospholamban Gene Is Associated with Cardiac Repolarisation (2018) (0)
ALLHAT Revisited: How Have the Findings Held Up 5 Years Later? (2007) (0)
Advances in genomics of blood pressure—time for translation (2013) (0)
Association of the CYP11B1 and CYP11B2 gene polymorphisms with hypertension in the British Genetics of Hypertension case-control study (2007) (0)
Genetics and Genomics of Systemic Hypertension (2018) (0)
Abstract 4152: Did Older or Younger Patients Benefit More from Amlodipine based vs Atenolol based Therapy in ASCOT-BPLA? (2006) (0)
Loci on Chromosomes 5p and 20q are Linked to Multiple Hypertension Phenotypes in the BRItish Genetics of HyperTension (BRIGHT) Study: LB13 (2005) (0)
THE WNK KINASES — NEW INSIGHTS INTO BLOOD PRESSURE REGULATING MECHANISMS (2004) (0)
Interstitial expansion in pressure overload left ventricular hypertrophy (2013) (0)
Whole genome sequencing identiﬁes multiple loci for critical 1 illness caused by COVID-19 2 (2021) (0)
Discovery and validation of 107 blood pressure loci from UK Biobank offers novel biological insights into cardiovascular risk (2016) (0)
PP.LB03.07: BLOOD-PRESSURE ASSOCIATED VARIANTS IN NPR3 AFFECT HUMAN VASCULAR SMOOTH MUSCLE CELLS PROLIFERATION AND CALCIUM RESPONSE TO ANGIOTENSIN II (2015) (0)
University of Groningen Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci Tragante, (2014) (0)
Genome-wide association analysis identifies the MTHFR-CLCN6-NPPA-NPPB gene cluster as an important influence on BNP levels-implications for the use of BNP levels in the diagnosis and therapeutic monitoring of heart failure-an ASCOT sub study (2012) (0)
CYP2C19 loss of function alleles are not associated with higher prevalence of gastrointestinal bleeds in those who have been prescribed antidepressants: Analysis in a British-South Asian cohort. (2023) (0)
Evolution, essential hypertension and the high arterial pressures in certain athletic breeds of dogs. (2011) (0)
The MRC BRIGHT study: Demographic and biochemical characteristics of the sibling-pair resource (2004) (0)
Publisher Correction: Telomerecat: A ploidy-agnostic method for estimating telomere length from whole genome sequencing data (2018) (0)
Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data (2019) (0)
University of Dundee Prevention And Treatment of Hypertension With Algorithm-based therapy ( PATHWAY ) number 2 (2015) (0)
Achievement of Blood Pressure Targets and Safety of Azilsartan Medoxomil/Chlorthalidone Fixed Dose Combination versus Azilsartan Medoxomil in Hypertensive Patients Uncontrolled on Monotherapy (2015) (0)
Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction (2020) (0)
Familial Atherosclerotic Disease and Hypertension Localised To Chromosome 7p in the British Genetics of Hypertension Study: LB19 (2006) (0)
Publisher Correction: Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals (2021) (0)
Evaluation of cardiovascular risk equations using the ASCOT cohort (2001) (0)
Abstract 15422: Genetic Predisposition to High Blood Pressure and Lifestyle: Associations With Midlife Blood Pressure Levels and Cardiovascular Health Outcomes (2017) (0)
PPARGC1 beta is a genetic determinant of the cardiovascular risk factor, Thromboxane A2-an Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT) sub-study (2011) (0)
Diffuse interstitial fibrosis in well-controlled hypertension (2013) (0)
Project Report - NHS Genomic Medicine Centres: Process and Participant Materials used in the 100,000 Genomes Project (2016) (0)
Supplementary Material (nature09270-s1) (2012) (0)
Clinical whole-genome sequencing from routine formalin-fixed, paraffin-embedded specimens: pilot study for the 100,000 Genomes Project (2018) (0)
Association of Blood Pressure With Genetic Variation in WNK Kinases in a White European Population (2005) (0)
Genome wide association study of blood pressure extremes identifies variant in uromodulin gene associated with hypertension (2010) (0)
Investigation of the endocrine and haemodynamic changes in resistant hypertension, and its response to spironolactone or amiloride: the PATHWAY-2 mechanisms study (2018) (0)
HYPERTENSIVE PATIENTS WITH GREATER GENETIC RISK RESPOND LESS EFFECTIVELY TO TREATMENT AND ARE MORE LIKELY TO BE TREATMENT RESISTANT (2021) (0)
1990-2000: progress in determining high blood pressure genes. (2000) (0)
SLC2A9 is a high affinity urate transporter in man. (2008) (0)
Genome-wide association meta-analysis of 30,000 samples identifies seven novel for quantitative traits. (2018) (0)
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (2018) (0)
No association of the epithelial sodium channel beta-subunit T594M variant with essential hypertension in an African Caribbean population (2000) (0)
Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits (2018) (0)
Title : Six new loci associated with body mass index highlight a neuronal influence on body weight regulation (0)
Highly Comprehensive Genomic Testing for CLL: WGS, One Key to CLL Patient Stratification (2018) (0)
1.P.377 Evaluation of the angiotensinogen locus in human essential hypertension: An European study (1997) (0)
100,000 Genomes Project: Cancer program (2018) (0)
Whole genome sequences discriminate hereditary hemorrhagic telangiectasia phenotypes by non-HHT deleterious DNA variation (2022) (0)
Annual Scientific Meeting of the British Hypertension Society, Cambridge, UK, 11–13 September 2000 (2000) (0)
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (2019) (0)
Standardization of advanced lipoprotein testing: The BioSITrace project (2019) (0)
Title : Germline selection shapes the landscape of human mitochondrial DNA (2019) (0)
Omega-3 Fatty Acid Differences in a Saudi Arabia Population Compared to a US Population and Cardiovascular Risk† (2015) (0)
OR-4: Who should have their cholesterol measured? A comparison of selective cholesterol screening methods (2002) (0)
Abstract 590: LDL Particle Number is Associated With Incident Atherosclerotic Cardiovascular Disease Among Persons With a 10-Year Risk of <7.5% (2014) (0)
Abstracts from the 2014 Annual Scientific Meeting of the BHS (2014) (0)
Genetic Markers in Prediction of Cardiovascular Disease (2015) (0)
The Ace I/D Polymorphism Identifies Cad in Low Risk Welsh Subjects (1995) (0)
GENOME-WIDE ASSOCIATION STUDY FOR PHARMACOGENETIC RESPONSE OF BLOOD PRESURE TO BETA BLOCKER AND CALCIUM CHANNEL BLOCKER DRUGS (2021) (0)
Equal access to pharmacogenomics testing: The ethical imperative for population‐wide access in the UK NHS (2023) (0)
[OP.7C.02] BLOOD PRESSURE-ASSOCIATED POLYMORPHISMS IN SLC4A7 (SODIUM/BICARBONATE CO-TRANSPORTER NBCN1) ARE LINKED WITH GENE EXPRESSION AND INTRACELLULAR PH REGULATION (2016) (0)
Abstract 14943: Comparison of Fasting and Nonfasting Lipoprotein Subfractions and Size in 13,460 Apparently Healthy Individuals (2017) (0)
MON-442 Evaluation of Copeptin as a Surrogate for AVP in the Diagnosis of Water Metabolism Disorders (2019) (0)
Synthetic peptides as tools for investigating the pathogenicity of disease: humoral hypercalcemia of malignancy. (1989) (0)
TREATING HYPERTENSION WITH FIRST-LINE THERAPIES IS CHEAPER THAN DOING NOTHING: LB3.2 (2011) (0)
Maleimido-Based Reagents for Indirect, Mild and Specific Radioiodolabeling of Analogs of Parathyroid Hormone (PTH) and PTH-Related Protein, (1992) (0)
Nuclear-mitochondrial DNA segments resemble paternally inherited mitochondrial DNA in humans (2020) (0)
Whole genome sequencing reveals host factors underlying critical Covid-19 Accelerated Article Preview (2022) (0)
PLoS medicine Volume: 5 ISSN: 1549-1676 ISO Abbreviation: PLoS Med. Publication Date: 2008 Oct (2008) (0)
ErratumErratum to “Evolution, essential hypertension and the high arterial pressures in certain athletic breeds of dogs” [The Veterinary Journal 188 (2011) 125–127] (2011) (0)
Absence of linkage of the epithelial sodium channel to hypertension in African Caribbeans (1997) (0)
Pergamon Press Oxford · New York · Seoul · Tokyo the Role of Atrial Natriuretic Peptide (anp) in Chronic Liver Disease (0)
WNK1 - functional analyses of variants associated with blood pressure and essential hypertension (2008) (0)
Synthesis and Synthetic Manipulations of Peptides Derived from Parathyroid Hormone and Parathyroid Hormone-Related Protein (1993) (0)
VARIANTS AND HAPLOTYPES OF THE ANGIOTENSINOGEN GENE ARE ASSOCIATED WITH HYPERTENSION IN THE CAERPHILLY PROSPECTIVE STUDY: PE.14 (2005) (0)
Coronary Artery Disease Risk in a Saudi Arabia Population, Lipoprotein Subclass Distribution, and Gender Differences (2015) (0)
Introducing Cambridge Prisms: Precision Medicine (2023) (0)
A genetic risk score is associated with statin-induced LDL-cholesterol lowering Short title: Genetic risk score for LDL-cholesterol lowering (2016) (0)
Proportion of patients with previously uncontrolled hypertension who achieve target blood pressure through participation in the BHS's prevention and treatment of hypertension with algorithm based therapy (PATHWAY) trials (2012) (0)
Authors’ reply to Harding and colleagues, Taylor, Cruickshank, and El Turabi and Payne (2011) (0)
AMBULATORY ARTERIAL STIFFNESS INDEX PREDICTS CARDIOVASCULAR MORBIDITY AND MORTALITY IN TREATED HYPERTENSIVE PATIENTS – AN ANGLO-SCANDINAVIAN CARDIAC OUTCOME TRIAL SUB-STUDY: 2A.03 (2010) (0)
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (2018) (0)
Whole-genome sequencing of patients with rare diseases in a national health system (2020) (0)
Validation of Association of Hypertension at the CYP11B1/B2 Locus in Caucasians. (2010) (0)
Whole genome sequencing in the clinic identifies CLL patients with high risk of relapse: pilot study for the 100,000 Genomes Project (2018) (0)
A Novel Calciotropic Hormone, Parathyroid Hormone-Related Protein, Biology and Structure/Function Studies, (1992) (0)
ION Mobility Analysis Of Lipoprotein Subfractions Suggests Three Independent Mechanisms Of Cardiovascular Risk (2009) (0)
Genetic analyses identify brain structures related to cognitive impairment associated with elevated blood pressure. (2023) (0)
Variants of the human mu type glutathione-s-transferase (GSTM) gene family are associated with hypertension (2006) (0)
Synthetic Signal Peptides of Parathyroid Hormone: Probes for Components of the Secretory Apparatus (1989) (0)
SAT-018 Differences In Assay Results Can Be Traced To The Metabolism Of Administered Progesterone In Women Taking Progesterone Supplementation (2019) (0)
Telomerecat: A ploidy-agnostic method for estimating telomere length from whole genome sequencing data (2018) (0)
Systematic analysis of 123 candidate genes reveals two novel genes for hypertension (2008) (0)
Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits (2018) (0)
A study of Xho 1 polymorphisms of the human proatrial natriuretic peptide gene in essential hypertension (1989) (0)
Abstract 630: Lipoprotein Subclasses by Ion Mobility and First Cardiovascular Events: An Analysis of 11,227 Participants From the JUPITER Trial (2014) (0)
21. Cardiovascular disease risk attributed to blood fish oil (omega-3 fatty acid) levels differ significantly in Saudi Men and Women (2015) (0)
Analysis of Lipoprotein Subclasses and Apolipoprotein Levels of African-American Males with Type 2 Diabetes (2014) (0)
MON-487 Simultaneous Monitoring of 13 IGF-1 Variants in a Clinical Mass Spectrometry Assay (2019) (0)
Abstract 232: Cost-effectiveness Analysis of Lipoprotein Subfraction Testing in Patients at Intermediate Risk of Cardiovascular Events (2015) (0)
1 .P 377 Evaluation of the angiotensinogen locus in human essential lipidic composition of de patients with arterial hypertension and without hypertension: An European study obesity. (1997) (0)

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