Mark Chance
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American chemist, Nutritionist
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Mark Chancemedical Degrees
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Medical Chemistry
Mark Chance's Degrees
- Bachelors Chemistry University of California, Berkeley
- Masters Nutrition Stanford University
Why Is Mark Chance Influential?
(Suggest an Edit or Addition)According to Wikipedia, Mark Chance is an American chemist currently interested in structural and cellular proteomics. He is currently the Charles W. and Iona A. Mathias Professor of Cancer Research at Case Western Reserve University.
Mark Chance's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Hydroxyl radical-mediated modification of proteins as probes for structural proteomics. (2007) (564)
- Protein production and purification (2008) (529)
- C. elegans ORFeome version 1.1: experimental verification of the genome annotation and resource for proteome-scale protein expression (2003) (392)
- RNA folding at millisecond intervals by synchrotron hydroxyl radical footprinting. (1998) (303)
- Reversible methylation of promoter-bound STAT3 by histone-modifying enzymes (2010) (294)
- Nucleocapsid zinc fingers detected in retroviruses: EXAFS studies of intact viruses and the solution‐state structure of the nucleocapsid protein from HIV‐1 (1992) (275)
- Conformation transition kinetics of regenerated Bombyx mori silk fibroin membrane monitored by time-resolved FTIR spectroscopy. (2001) (231)
- Conserved waters mediate structural and functional activation of family A (rhodopsin-like) G protein-coupled receptors (2009) (230)
- Radiolytic protein footprinting with mass spectrometry to probe the structure of macromolecular complexes. (2006) (230)
- In situ analysis of mineral content and crystallinity in bone using infrared micro-spectroscopy of the nu(4) PO(4)(3-) vibration. (2001) (222)
- Regulation of NF-κB by NSD1/FBXL11-dependent reversible lysine methylation of p65 (2009) (221)
- Inhibition of the prostaglandin-degrading enzyme 15-PGDH potentiates tissue regeneration (2015) (206)
- Structural waters define a functional channel mediating activation of the GPCR, rhodopsin (2009) (181)
- The inducible kinase IKKi is required for IL-17-dependent signaling associated with neutrophilia and pulmonary inflammation (2011) (180)
- Millisecond radiolytic modification of peptides by synchrotron X-rays identified by mass spectrometry. (1999) (179)
- Structural genomics: A pipeline for providing structures for the biologist (2002) (169)
- An Integrative -omics Approach to Identify Functional Sub-Networks in Human Colorectal Cancer (2010) (157)
- Time-resolved synchrotron X-ray "footprinting", a new approach to the study of nucleic acid structure and function: application to protein-DNA interactions and RNA folding. (1997) (155)
- Radiolytic modification and reactivity of amino acid residues serving as structural probes for protein footprinting. (2005) (145)
- Structural genomics of protein phosphatases (2007) (144)
- Crystal structure of native RPE65, the retinoid isomerase of the visual cycle (2009) (140)
- Alcohol Dehydrogenase Restricts the Ability of the Pathogen Candida albicans To Form a Biofilm on Catheter Surfaces through an Ethanol-Based Mechanism (2006) (136)
- Metallomics and metalloproteomics (2008) (133)
- Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth (2017) (131)
- Assembly of a GPCR-G Protein Complex (2019) (127)
- The KSEA App: a web‐based tool for kinase activity inference from quantitative phosphoproteomics (2017) (121)
- Discovery and Scoring of Protein Interaction Subnetworks Discriminative of Late Stage Human Colon Cancer*S (2009) (115)
- Regulation of NF κB by NSD1/FBXL11-dependent reversible lysine methylation of p65 (2009) (112)
- Radiolytic modification of basic amino acid residues in peptides: probes for examining protein-protein interactions. (2003) (109)
- Structural proteomics of macromolecular assemblies using oxidative footprinting and mass spectrometry. (2005) (108)
- Hydroxyl radical probe of protein surfaces using synchrotron X-ray radiolysis and mass spectrometry (2002) (107)
- Principles of RNA compaction: insights from the equilibrium folding pathway of the P4-P6 RNA domain in monovalent cations. (2004) (107)
- Structural mass spectrometry of proteins using hydroxyl radical based protein footprinting. (2011) (101)
- Linkage of functional and structural heterogeneity in proteins: dynamic hole burning in carboxymyoglobin. (1987) (100)
- Determination of macromolecular folding and structure by synchrotron x-ray radiolysis techniques. (2001) (98)
- Mapping the G-actin binding surface of cofilin using synchrotron protein footprinting. (2002) (97)
- Probing the structural dynamics of nucleic acids by quantitative time-resolved and equilibrium hydroxyl radical "footprinting". (2002) (95)
- Electrospray-assisted modification of proteins: a radical probe of protein structure. (1999) (93)
- Folding mechanism of the Tetrahymena ribozyme P4-P6 domain. (2000) (92)
- Visualizing the Ca2+-dependent activation of gelsolin by using synchrotron footprinting (2003) (92)
- Future directions of structural mass spectrometry using hydroxyl radical footprinting. (2010) (92)
- Radiolytic modification of sulfur-containing amino acid residues in model peptides: fundamental studies for protein footprinting. (2005) (88)
- Center for Synchrotron Biosciences' U2B beamline: an international resource for biological infrared spectroscopy. (2002) (88)
- Structure and dynamics of the actin filament. (2005) (87)
- Monovalent cations mediate formation of native tertiary structure of the Tetrahymena thermophila ribozyme (2002) (85)
- Metalloproteomics: high-throughput structural and functional annotation of proteins in structural genomics. (2005) (81)
- Secondary reactions and strategies to improve quantitative protein footprinting. (2005) (81)
- Protein–protein interaction networks and subnetworks in the biology of disease (2011) (81)
- Phosphorylation of CDK9 at Ser175 Enhances HIV Transcription and Is a Marker of Activated P-TEFb in CD4+ T Lymphocytes (2013) (81)
- Subnetwork State Functions Define Dysregulated Subnetworks in Cancer (2010) (80)
- Visualizing the kinetic power stroke that drives proton-coupled Zn(II) transport (2014) (78)
- Following the folding of RNA with time-resolved synchrotron X-ray footprinting. (1998) (77)
- Concerted binding and bending of DNA by Escherichia coli integration host factor. (2002) (77)
- The Beamline X28C of the Center for Synchrotron Biosciences: a national resource for biomolecular structure and dynamics experiments using synchrotron footprinting. (2007) (76)
- Identification of conformational substates involved in nitric oxide binding to ferric and ferrous myoglobin through difference Fourier transform infrared spectroscopy (FTIR). (1997) (75)
- Time-resolved synchrotron X-ray footprinting and its application to RNA folding. (2000) (74)
- Quantitative mapping of protein structure by hydroxyl radical footprinting-mediated structural mass spectrometry: a protection factor analysis. (2015) (74)
- Kinetic and structural characterization of spinach carbonic anhydrase. (1994) (74)
- Structural basis of ligand interaction with atypical chemokine receptor 3 (2017) (73)
- Metalloproteomics: forward and reverse approaches in metalloprotein structural and functional characterization. (2011) (72)
- In situ chemistry of osteoporosis revealed by synchrotron infrared microspectroscopy. (2003) (71)
- Cytochrome c peroxidase compound ES is identical with horseradish peroxide compound I in iron-ligand distances. (1986) (71)
- A method for examining the chemical basis for bone disease: synchrotron infrared microspectroscopy. (1998) (70)
- X-ray absorption studies of myoglobin peroxide reveal functional differences between globins and heme enzymes. (1986) (69)
- Picosecond time-resolved Raman studies of photodissociated carboxymyoglobin (1985) (69)
- Conformational changes during the gating of a potassium channel revealed by structural mass spectrometry. (2010) (69)
- Identification of in Vivo Disulfide Conformation of TRPA1 Ion Channel* (2011) (68)
- Characterization of bone mineral composition in the proximal tibia of cynomolgus monkeys: effect of ovariectomy and nandrolone decanoate treatment. (2002) (67)
- Conformational dynamics of activation for the pentameric complex of dimeric G protein-coupled receptor and heterotrimeric G protein. (2012) (67)
- Crystal structure of Escherichia coli L-arabinose isomerase (ECAI), the putative target of biological tagatose production. (2006) (66)
- Network Signatures of Survival in Glioblastoma Multiforme (2013) (64)
- EXCITED STATE DYNAMICS OF BACTERIORHODOPSIN REVEALED BY TRANSIENT STIMULATED EMISSION SPECTRA (1996) (64)
- Unfolding of apomyoglobin examined by synchrotron footprinting. (2001) (63)
- High-throughput computational and experimental techniques in structural genomics. (2004) (63)
- Kinetic, structural, and spectroscopic identification of geminate states of myoglobin: a ligand binding site on the reaction pathway. (1987) (62)
- Apigenin blocks IKKα activation and suppresses prostate cancer progression (2015) (61)
- Cyclin-dependent kinase 5 activity is required for T cell activation and induction of experimental autoimmune encephalomyelitis (2010) (59)
- Structure of RPE65 isomerase in a lipidic matrix reveals roles for phospholipids and iron in catalysis (2012) (57)
- Novel Urinary Protein Biomarkers Predicting the Development of Microalbuminuria and Renal Function Decline in Type 1 Diabetes (2012) (56)
- Structural Analysis of Gelsolin Using Synchrotron Protein Footprinting* (2003) (56)
- Gene interaction enrichment and network analysis to identify dysregulated pathways and their interactions in complex diseases (2012) (55)
- Structural reorganization of the transferrin C-lobe and transferrin receptor upon complex formation: the C-lobe binds to the receptor helical domain. (2003) (55)
- Visualizing Arp2/3 complex activation mediated by binding of ATP and WASp using structural mass spectrometry (2007) (55)
- Monovalent ion-mediated folding of the Tetrahymena thermophila ribozyme. (2004) (54)
- Complementary structural mass spectrometry techniques reveal local dynamics in functionally important regions of a metastable serpin. (2008) (54)
- Electron Microscopic and Proteomic Comparison of Terminal Branches of the Trigeminal Nerve in Patients with and without Migraine Headaches (2014) (54)
- Integrated algorithms for high-throughput examination of covalently labeled biomolecules by structural mass spectrometry. (2009) (54)
- Purification of a Variant-specific Surface Protein of Giardia lamblia and Characterization of its Metal-binding Properties (*) (1995) (53)
- Network biology methods integrating biological data for translational science (2012) (52)
- RADIOLYTIC MODIFICATION OF ACIDIC AMINO ACIDS: NEW PROBES OF PROTEIN FOOTPRINTING (2004) (51)
- Gene, pathway and network frameworks to identify epistatic interactions of single nucleotide polymorphisms derived from GWAS data (2012) (50)
- Iron L-Edge X-ray Absorption Spectroscopy of Myoglobin Complexes and Photolysis Products (1997) (50)
- Protein Footprinting Comes of Age: Mass Spectrometry for Biophysical Structure Assessment* (2017) (50)
- High-valent manganese in polyoxotungstates-1. Manganese(IV) keggin derivatives (1995) (50)
- New York-Structural GenomiX Research Consortium (NYSGXRC): A Large Scale Center for the Protein Structure Initiative (2005) (50)
- Proteomic changes during intestinal cell maturation in vivo. (2008) (50)
- Infrared Absorption Investigations Confirm the Extraterrestrial Origin of Carbonado Diamonds (2006) (48)
- A comparison of functional and structural consequences of the tyrosine B10 and glutamine E7 motifs in two invertebrate hemoglobins (Ascaris suum and Lucina pectinata). (1997) (47)
- Proteomics Analysis Identifies Molecular Targets Related to Diabetes Mellitus-associated Bladder Dysfunction *S (2008) (46)
- Continuous-wave quantum yields of various cobalamins are influenced by competition between geminate recombination and cage escape. (1993) (46)
- Evidence for proximal control of ligand specificity in hemeproteins: Absorption and Raman studies of cryogenically trapped photoproducts of ligand bound myoglobins☆ (1991) (46)
- The ybeY protein from Escherichia coli is a metalloprotein. (2005) (46)
- Extended x-ray absorption fine structure studies of a retrovirus: equine infectious anemia virus cysteine arrays are coordinated to zinc. (1992) (45)
- Quantitative Protein Topography Analysis and High-Resolution Structure Prediction Using Hydroxyl Radical Labeling and Tandem-Ion Mass Spectrometry (MS)* (2015) (45)
- The ClpP N-terminus coordinates substrate access with protease active site reactivity. (2008) (44)
- Visualizing water molecules in transmembrane proteins using radiolytic labeling methods. (2010) (44)
- Structural reorganization of proteins revealed by radiolysis and mass spectrometry: G-actin solution structure is divalent cation dependent. (2003) (44)
- Geometric conformations of intermediates of B12 catalysis by x-ray edge spectroscopy: cobalt(I) B12, cobalt(II) B12, and base-off adenosylcobalamin (1991) (43)
- Stability and cooperativity of individual tertiary contacts in RNA revealed through chemical denaturation (2000) (42)
- Synchrotron protein footprinting supports substrate translocation by ClpA via ATP-induced movements of the D2 loop. (2008) (42)
- Proteomics of Skin Proteins in Psoriasis: From Discovery and Verification in a Mouse Model to Confirmation in Humans* (2014) (41)
- Structural Characterization of HIV gp41 with the Membrane-proximal External Region* (2010) (41)
- Characterization of metalloproteins by high-throughput X-ray absorption spectroscopy. (2011) (39)
- O2 and CO reactions with heme proteins: quantum yields and geminate recombination on picosecond time scales. (1990) (39)
- Low frequency vibrations of amino acid homopolymers observed by synchrotron far-IR absorption spectroscopy: Excited state effects dominate the temperature dependence of the spectra (1999) (39)
- Examining the conformational dynamics of macromolecules with time-resolved synchrotron X-ray 'footprinting'. (1997) (39)
- Structure and dynamics of protein waters revealed by radiolysis and mass spectrometry (2012) (39)
- Synchrotron Infrared Microspectroscopy (2006) (39)
- A Metastable Contact and Structural Disorder in the Estrogen Receptor Transactivation Domain. (2019) (38)
- Structural and functional significance of inhomogeneous line broadening of band III in hemoglobin and Fe-Mn hybrid hemoglobins. (1990) (37)
- Multiple monovalent ion-dependent pathways for the folding of the L-21 Tetrahymena thermophila ribozyme. (2003) (37)
- Nanosecond transient absorption spectroscopy of coenzyme B12. Quantum yields and spectral dynamics. (1990) (36)
- Characterizing monoclonal antibody structure by carboxyl group footprinting (2015) (36)
- A proteomic study of myosin II motor proteins during tumor cell migration. (2011) (36)
- Multidomain architecture of estrogen receptor reveals interfacial cross-talk between its DNA-binding and ligand-binding domains (2018) (36)
- Multiple Glycosaminoglycan-binding Epitopes of Monocyte Chemoattractant Protein-3/CCL7 Enable It to Function as a Non-oligomerizing Chemokine* (2014) (35)
- Insights into Substrate Specificity and Metal Activation of Mammalian Tetrahedral Aspartyl Aminopeptidase* (2012) (35)
- Structural Allostery and Binding of the Transferrin·Receptor Complex*S (2005) (35)
- Linkage of monovalent and divalent ion binding in the folding of the P4-P6 domain of the Tetrahymena ribozyme. (2002) (35)
- Installation and testing of a focusing mirror at beamline X28C for high flux x-ray radiolysis of biological macromolecules. (2008) (34)
- Radiolytic modification of acidic amino acid residues in peptides: probes for examining protein-protein interactions. (2003) (34)
- Reliable Determination of Site-Specific In Vivo Protein N-Glycosylation Based on Collision-Induced MS/MS and Chromatographic Retention Time (2014) (34)
- Semi-automated, single-band peak-fitting analysis of hydroxyl radical nucleic acid footprint autoradiograms for the quantitative analysis of transitions. (2004) (34)
- Development of a microsecond X-ray protein footprinting facility at the Advanced Light Source. (2014) (34)
- Human Biomarker Discovery and Predictive Models for Disease Progression for Idiopathic Pneumonia Syndrome Following Allogeneic Stem Cell Transplantation* (2012) (34)
- DNA Binding Provides a Molecular Strap Activating the Adenovirus Proteinase*S (2004) (34)
- Molecular Targets for Diabetes Mellitus-associated Erectile Dysfunction* (2009) (33)
- Synchrotron Protein Footprinting: A Technique to Investigate Protein-Protein Interactions (2001) (33)
- Formation of a square-planar Co(I) B12 intermediate. Implications for enzyme catalysis. (1992) (33)
- Myometrial Transcriptional Signatures of Human Parturition (2019) (32)
- Urinary Protein Profiles in a Rat Model for Diabetic Complications* (2009) (31)
- During Hepatitis C Virus (HCV) Infection and HCV-HIV Coinfection, an Elevated Plasma Level of Autotaxin Is Associated With Lysophosphatidic Acid and Markers of Immune Activation That Normalize During Interferon-Free HCV Therapy. (2016) (31)
- Systems Biology Analyses of Gene Expression and Genome Wide Association Study Data in Obstructive Sleep Apnea (2011) (31)
- Target selection and annotation for the structural genomics of the amidohydrolase and enolase superfamilies (2009) (31)
- High-Resolution Hydroxyl Radical Protein Footprinting: Biophysics Tool for Drug Discovery. (2018) (30)
- Integrating phosphoproteomics in systems biology (2014) (29)
- Oxidative stress status accompanying diabetic bladder cystopathy results in the activation of protein degradation pathways (2011) (29)
- SAHA enhances Proteostasis of epilepsy-associated α1(A322D)β2γ2 GABA(A) receptors. (2013) (29)
- Identification of structural markers for vitamin B12 and other corrinoid derivatives in solution using FTIR spectroscopy. (1991) (28)
- Extended X-ray absorption fine structure studies on the iron-containing subunit of ribonucleotide reductase from Escherichia coli. (1987) (28)
- Solution structure and interdomain interactions of the Saccharomyces cerevisiae "TATA binding protein" (TBP) probed by radiolytic protein footprinting. (2003) (26)
- GABARAP sequesters the FLCN-FNIP tumor suppressor complex to couple autophagy with lysosomal biogenesis. (2021) (26)
- Synchrotron radiolysis and mass spectrometry: a new approach to research on the actin cytoskeleton. (2004) (26)
- Probing the structure of ribosome assembly intermediates in vivo using DMS and hydroxyl radical footprinting. (2016) (26)
- Three-dimensional structure of cofilin bound to monomeric actin derived by structural mass spectrometry data (2007) (26)
- A Hybrid Structural Approach to Analyze Ligand Binding by the Serotonin Type 4 Receptor (5-HT4)* (2013) (26)
- Conformational changes in guanylate cyclase-activating protein 1 induced by Ca2+ and N-terminal fatty acid acylation. (2010) (25)
- Movement of Fe with respect to the heme plane in the R-T transition of carp hemoglobin. An extended x-ray absorption fine structure study. (1986) (25)
- Sulfur-containing cobalamins: X-ray absorption spectroscopic characterization. (1994) (25)
- A Synchrotron-Based Hydroxyl Radical Footprinting Analysis of Amyloid Fibrils and Prefibrillar Intermediates with Residue-Specific Resolution (2014) (25)
- Efficiently Enumerating All Connected Induced Subgraphs of a Large Molecular Network (2014) (25)
- Structure of an intermediate of coenzyme B12 catalysis by EXAFS : Cobalt(II) B12 (1990) (24)
- Proteomics and Pathway Mapping Analyses Reveal Phase-Dependent Over-Expression of Proteins Associated with Carbohydrate Metabolic Pathways in Candida albicans Biofilms (2008) (24)
- Key inflammatory pathway activations in the MCI stage of Alzheimer’s disease (2019) (23)
- Proteomic Signatures of Human Oral Epithelial Cells in HIV-Infected Subjects (2011) (23)
- MOBAS: identification of disease-associated protein subnetworks using modularity-based scoring (2015) (22)
- Structural analysis of a highly glycosylated and unliganded gp120-based antigen using mass spectrometry. (2010) (22)
- DNA and protein footprinting analysis of the modulation of DNA binding by the N-terminal domain of the Saccharomyces cerevisiae TATA binding protein. (2007) (21)
- Acetyl-l-carnitine increases mitochondrial protein acetylation in the aged rat heart (2015) (21)
- X-ray absorption spectroscopy of the corrinoid/iron-sulfur protein involved in acetyl coenzyme A synthesis by Clostridium thermoaceticum (1993) (21)
- Time-Resolved X-ray Absorption Spectroscopy of Photoreduced Base-off Cob(II)alamin Compared to the Co(II) Species in Clostridium thermoaceticum (1996) (21)
- Robust inference of kinase activity using functional networks (2020) (21)
- Biochemical implications of a three-dimensional model of monomeric actin bound to magnesium-chelated ATP. (2007) (21)
- Discovery of common sequences absent in the human reference genome using pooled samples from next generation sequencing (2014) (21)
- Extent of trans effects in (nonalkyl)cobalamins : steric effects control the Co-N distance to 5,6-dimethylbenzimidazole (1992) (20)
- Prediction and Testing of Biological Networks Underlying Intestinal Cancer (2010) (19)
- Inner ear proteomics of mouse models for deafness, a discovery strategy (2006) (19)
- Protein Footprinting: Auxiliary Engine to Power the Structural Biology Revolution. (2020) (19)
- Approaches to biomarkers in human colorectal cancer: looking back, to go forward. (2009) (19)
- Global mapping of structural solutions provided by the extended X-ray absorption fine structure ab initio code FEFF 6.01: structure of the cryogenic photoproduct of the myoglobin-carbon monoxide complex. (1996) (19)
- Extended X-ray Absorption Fine Structure Analysis of Coenzyme B12 Bound to Methylmalonyl-Coenzyme A Mutase Using Global Mapping Techniques† (1997) (19)
- Differential expression of fibulin family proteins in the para-cervical weak zone and other areas of human fetal membranes. (2009) (18)
- Structural basis for modification of flavonol and naphthol glucoconjugates by Nicotiana tabacum malonyltransferase (NtMaT1) (2012) (18)
- Drug Intervention Response Predictions with Paradigm (DIRPP) Identifies Drug Resistant Cancer Cell Lines and Pathway Mechanisms of Resistance (2013) (18)
- Myosin binding surface on actin probed by hydroxyl radical footprinting and site-directed labels. (2011) (18)
- CoPhosK: A method for comprehensive kinase substrate annotation using co-phosphorylation analysis (2018) (17)
- Structure of a putative BenF‐like porin from Pseudomonas fluorescens Pf‐5 at 2.6 Å resolution (2010) (17)
- Synchrotron X-ray footprinting on tour. (2014) (17)
- Interplay of transcriptional signaling by progesterone, cyclic AMP, and inflammation in myometrial cells: implications for the control of human parturition. (2019) (16)
- Plasma Proteome Analysis Reveals Overlapping, yet Distinct Mechanisms of Immune Activation in Chronic HCV and HIV Infections (2013) (16)
- Integrated microRNA and mRNA network analysis of the human myometrial transcriptome in the transition from quiescence to labor†,‡ (2018) (16)
- Applications of fluorescence-assisted infrared microspectroscopy to the study of osteoporosis (1999) (16)
- High-throughput expression, purification, and characterization of recombinant Caenorhabditis elegans proteins. (2003) (16)
- Proteomics, bioinformatics and targeted gene expression analysis reveals up-regulation of cochlin and identifies other potential biomarkers in the mouse model for deafness in Usher syndrome type 1F. (2010) (16)
- Probing conformational changes upon photolysis: FTIR studies of the low temperature liganded and photoproduct states of oxy- and carbonmonoxymyoglobin (1994) (16)
- Structural and electronic factors that influence oxygen affinities: a spectroscopic comparison of ferrous and cobaltous oxymyoglobin. (1995) (16)
- Myoglobin recombination at low temperature. Two phases revealed by Fourier transform infrared spectroscopy. (1987) (16)
- Phosphoproteomics Profiling of Nonsmall Cell Lung Cancer Cells Treated with a Novel Phosphatase Activator (2017) (16)
- Identification of Conformational Substates in Oxymyoglobin through the pH-Dependence of the Low-Temperature Photoproduct Yield (1996) (15)
- Structural and electronic factors in heterolytic cleavage: formation of the Co(I) intermediate in the corrinoid/iron-sulfur protein from Clostridium thermoaceticum. (1995) (15)
- A combined global and local approach to elucidate spatial organization of the Mycobacterial ParB-parS partition assembly. (2011) (15)
- Integrative Analysis of Common Neurodegenerative Diseases Using Gene Association, Interaction Networks and mRNA Expression Data (2012) (15)
- A quantitative proteomic approach for detecting protein profiles of activated human myeloid dendritic cells. (2012) (15)
- Tissue Specific Dysregulated Protein Subnetworks in Type 2 Diabetic Bladder Urothelium and Detrusor Muscle* (2015) (14)
- Structural Analysis of Proinsulin Hexamer Assembly by Hydroxyl Radical Footprinting and Computational Modeling* (2011) (14)
- A Practical Guide to iSPOT Modeling: An Integrative Structural Biology Platform. (2017) (14)
- Nanosecond transient absorption spectroscopy. (1993) (14)
- The XFP (17-BM) beamline for X-ray footprinting at NSLS-II (2019) (14)
- Pathway Analyses and Understanding Disease Associations (2013) (14)
- Comparison of epigenetic profiles of human oral epithelial cells from HIV-positive (on HAART) and HIV-negative subjects (2013) (14)
- MAGNET: MicroArray Gene expression and Network Evaluation Toolkit (2012) (13)
- Finding lost genes in GWAS via integrative-omics analysis reveals novel sub-networks associated with preterm birth. (2016) (13)
- Discovery of a Redox Thiol Switch: Implications for Cellular Energy Metabolism* (2020) (13)
- Inflammatory pathway analytes predicting rapid cognitive decline in MCI stage of Alzheimer’s disease (2020) (13)
- A dynamical systems model of progesterone receptor interactions with inflammation in human parturition (2016) (13)
- Proteomic and bioinformatics profile of paired human alveolar macrophages and peripheral blood monocytes (2015) (13)
- Hydroxyl Radical-Mediated Modification of Proteins as Probes for Structural Proteomics (2007) (12)
- Regulation of endothelial hemoglobin alpha expression by Kruppel-like factors (2017) (12)
- Design and implementation of a rapid-mixer flow cell for time-resolved infrared microspectroscopy (2000) (12)
- PETALS: Proteomic Evaluation and Topological Analysis of a mutated Locus' Signaling (2010) (12)
- Beamline X29: a novel undulator source for X-ray crystallography. (2006) (11)
- Proteomic profiling of the hypothalamus in two mouse models of narcolepsy (2017) (11)
- Ligand binding channels reflected in the resonance Raman spectra of cryogenically trapped species of myoglobin. (1987) (11)
- Pharmacologic intervention targeting glycolytic‐related pathways protects against retinal injury due to ischemia and reperfusion (2009) (11)
- Time‐resolved x‐ray absorption spectroscopy on microsecond timescales: Implications for the examination of structural motions (1993) (11)
- Proteomics and Network Analyses Reveal Inhibition of Akt‐mTOR Signaling in CD4+ T Cells by Mycobacterium tuberculosis Mannose‐Capped Lipoarabinomannan (2017) (11)
- Human cobalophilin: the structure of bound methylcobalamin and a functional role in protecting methylcobalamin from photolysis. (1993) (11)
- A high-throughput approach to protein structure analysis. (2007) (11)
- Crystal structure of Clostridium acetobutylicum aspartate kinase (CaAk): An important allosteric enzyme for amino acids production (2011) (10)
- Circulating human CD4 and CD8 T cells do not have large intracellular pools of CCR5. (2011) (10)
- Temperature dependent coordination effects in base-off adenosyl and methylcobalamin by X-ray edge spectroscopy. (1993) (10)
- Proteome and Protein Network Analyses of Memory T Cells Find Altered Translation and Cell Stress Signaling in Treated Human Immunodeficiency Virus Patients Exhibiting Poor CD4 Recovery (2016) (10)
- X‐ray absorption studies on bacteriorhodopsin (1987) (10)
- Discovery of a Redox Thiol Switch: Implications for Cellular Energy Metabolism. (2020) (9)
- Global phosphoproteomics of CCR5-tropic HIV-1 signaling reveals reprogramming of cellular protein production pathways and identifies p70-S6K1 and MK2 as HIV-responsive kinases required for optimal infection of CD4+ T cells (2018) (9)
- Crystal structure of PrfA,the transcriptional regulator in Listeria monocytogenes (2003) (9)
- Ageing causes cytoplasmic retention of MaxiK channels in rat corporal smooth muscle cells (2007) (9)
- A Targeted Mass Spectrometry Assay for Detection of HIV Gag Protein Following Induction of Latent Viral Reservoirs. (2017) (9)
- Proteomic and bioinformatic profile of primary human oral epithelial cells. (2012) (8)
- Analysis of bone protein and mineral composition in bone disease using synchrotron infrared microspectroscopy (1999) (8)
- Fast Protein Footprinting by X-ray Mediated Radical Trifluoromethylation. (2020) (8)
- Identifying stage-specific protein subnetworks for colorectal cancer (2012) (8)
- Characterizing monoclonal antibody structure by carbodiimide/GEE footprinting (2014) (7)
- Splitting random forest (SRF) for determining compact sets of genes that distinguish between cancer subtypes (2012) (7)
- Catching RNA polymerase in the act of binding: intermediates in transcription illuminated by synchrotron footprinting. (2005) (7)
- Pacific symposium on biocomputing 2011 (2011) (7)
- Robust inference of kinase activity using functional networks (2021) (6)
- Linearity of network proximity measures: implications for set‐based queries and significance testing (2016) (6)
- Optics Concept for a Pair of Undulator Beamlines for MX. (2011) (6)
- Pairwise protein expression classifier for candidate biomarker discovery for early detection of human disease prognosis (2012) (6)
- Covalent Labeling Techniques for Characterizing Higher Order Structure of Monoclonal Antibodies (2015) (6)
- Electron Spin Echo Envelope Modulation and Extended X-ray Absorption Fine Structure Studies of Active Site Models of Oxygenated Cobalt-Substituted Hemoproteins: Correlating Electron-Nuclear Couplings and Metal−Ligand Bond Lengths (1997) (5)
- Development of the XFP beamline for x-ray footprinting at NSLS-II (2016) (5)
- New high-throughput endstation to accelerate the experimental optimization pipeline for synchrotron X-ray footprinting. (2021) (5)
- Recent Advances and Applications in Synchrotron X-Ray Protein Footprinting for Protein Structure and Dynamics Elucidation. (2016) (5)
- Ageing causes cytoplasmic retention of MaxiK channels in rat corporal smooth muscle cells (2007) (5)
- Nanosecond transient absorption spectroscopy of coenzyme B-12 (1989) (5)
- Co-Phosphorylation Networks Reveal Subtype-Specific Signaling Modules in Breast Cancer (2020) (5)
- Low-temperature optical spectroscopy: metalloprotein structure and dynamics. (1993) (4)
- A new method for examining the dynamics of macromolecules: Time-resolved synchrotron x-ray “footprinting” (1998) (4)
- Synchrotron infrared microspectroscopy as a means of studying the chemical composition of bone: applications to osteoarthritis (1997) (4)
- Technical Reports: Mapping a Functional Viral Protein in Solution Using Synchrotron X-ray Footprinting Technology (2005) (4)
- Footprinting Methods to Examine the Structure and Dynamics of Nucleic Acids (2006) (4)
- Synchrotron Radiolysis and Mass Spectrometry: A New Approach to Research on the Actin Cytoskeleton (2004) (4)
- Frontiers of Oncology: Biobanking Resources for the 21st Century (2011) (4)
- Movement of Fe with Respect to the Heme Plane in the RT Transition of Carp Hemoglobin (3)
- Optimizing biomedical discoveries as an engine of culture change in an academic medical center (2022) (3)
- Crystal Structure of Mn2+-bound Escherichia coli L-arabinose Isomerase (ECAI) and Implications in Protein Catalytic Mechanism and Thermo-Stability (2006) (3)
- BiC: a web server for calculating bimodality of coexpression between gene and protein networks (2011) (3)
- Structural studies on Na0.75CoO2 thermoelectric material at high pressures (2009) (3)
- Circulating human CD 4 and CD 8 T cells do not have large intracellular pools of CCR 5 (2011) (3)
- GABARAP membrane conjugation sequesters the FLCN-FNIP tumor suppressor complex to activate TFEB and lysosomal biogenesis (2021) (3)
- Proteins inform survival-based differences in patients with glioblastoma (2020) (3)
- The Utility of Mass Spectrometry Based Structural Proteomics in Biopharmaceutical Biologics Development (2012) (3)
- Corrigendum: Myometrial Transcriptional Signatures of Human Parturition (2019) (2)
- Functional characterization of co-phosphorylation networks (2022) (2)
- absorption spectroscopy Characterization of metalloproteins by high-throughput X-ray Material (2011) (2)
- Structurally distinct external solvent-exposed domains drive replication of major human prions (2021) (2)
- Multiplex Chemical Labeling of Amino Acids for Protein Footprinting Structure Assessment. (2022) (2)
- Biological infrared microspectroscopy at the National Synchrotron Light Source (2001) (2)
- Structural Basis for the Oligomerization-State Switch from a Dimer to a Trimer of an Engineered Cortexillin-1 Coiled-Coil Variant (2013) (2)
- Footprinting Methods to Examine the Structure and Dynamics of Proteins (2006) (2)
- Abstract 4936: Network signatures of survival in glioblastoma multiforme (2012) (1)
- Training the next generation of translational scientists: The Case Western Reserve University Translational Fellows Program (2022) (1)
- Integrative-omics for translational science-session introduction (2011) (1)
- Time-resolved Conformational Analysis during GPCR-Gs Coupling (2020) (1)
- Structural Genomics at the National Synchrotron Light Source (2002) (1)
- Linearity of network proximity measures: implications for set-based queries and significance testing. (2017) (1)
- Synchrotron infrared spectroscopy at beamline U2B (2005) (1)
- Recent advances in protein structure analysis (2006) (1)
- Prediction of Kinase-Substrate Associations Using The Functional Landscape of Kinases and Phosphorylation Sites (2022) (1)
- Radiolytic Footprinting Reveals Conformational Changes During Potassium Channel Gating (2010) (1)
- CoPhosK (2019) (1)
- Temporal and Sex-Linked Protein Expression Dynamics in a Familial Model of Alzheimer’s Disease (2022) (1)
- Preliminary crystallography confirms that the archaeal DNA-binding and tryptophan-sensing regulator TrpY is a dimer. (2010) (1)
- Algorithms for detecting complementary SNPs within a region of interest that are associated with diseases (2012) (1)
- IN VACUUM UNDULATOR TASK FORCE REPORT (1998) (1)
- Colorectal Cancer and Its Molecular Subsystems: Construction, Interpretation, and Validation (2013) (1)
- Omics and Prognostic Markers (2010) (1)
- Erratum: Ageing causes cytoplasmic retention of MaxiK channels in rat corporal smooth muscle cells (International Journal of Impotence Research (2007) 19, (371-377) DOI: 10.1038/sj.ijir.3901541) (2007) (1)
- Abstract 2698: Phosphoproteomics-guided anticancer drug combination design with a novel small-molecule PP2A activator (2018) (1)
- Albert einstein center for synchrotron biosciences (1999) (1)
- Abstract 3660: Apigenin suppresses IKK activation and downstream signaling leading to prostate cancer inhibition. (2013) (1)
- Crystal Structure of Nicotiana tabacum malonyltransferase (NtMat1) complexed with malonyl-coa (2011) (1)
- Human Biomarker Discovery and Predictive Models of Disease Progression and Response to Therapy for Idiopathic Pneumonia Syndrome (2012) (0)
- White Light Focusing Mirror (2007) (0)
- Crystal Structure of HIV gp41 with MPER (2010) (0)
- Proteomics of Carcinogen-Induced Tumor Development in Rats Consuming a Normal Diet (2015) (0)
- P4-044 THE GCAD CLOUD-BASEDWORKFLOW FOR PROCESSING WHOLE EXOME AND WHOLE GENOME DATA FROM THE ALZHEIMER’S DISEASE SEQUENCING PROJECT (0)
- National synchrotron light source 2000 annual users' meeting (2000) (0)
- Utilization of Landscape of Kinases and Phosphosites To Predict Kinase-Substrate Association (2022) (0)
- Towards macromolecular crystallography beamlines at NSLS-II (2011) (0)
- Abstract 4173: Drug target mutations as a mechanism of acquired resistance to small molecules activators of protein phosphatase 2a (2017) (0)
- Abstract 4220: Heterogeneous distribution of prognostic protein markers in glioblastoma (2018) (0)
- X-ray Footprinting of Profilin/Poly-L-Proline Peptide Complex (2000) (0)
- A proposed suite of macromolecular crystallography facilities for NSLS-II (2008) (0)
- Erratum: Quantitative mapping of protein structure by hydroxyl radical footprinting mediated structural mass spectrometry: A protection factor analysis (Biophysical Journal (2015) 108(107-115)) (2015) (0)
- 63,100-element oligonucleotide array activation revealed by profiling of psoriasis on the Novel mechanisms of T-cell and dendritic cell (2015) (0)
- Construction of Plasmids that Overproduce nif Regulatory Proteins (1984) (0)
- Multidomain architecture of estrogen receptor reveals interfacial cross-talk between its DNA-binding and ligand-binding domains (2018) (0)
- Proteomic analysis of tumor and adjacent non‐tumor intestinal tissue and tumor burden after iron supplementation in Apc Min/+ mice (2008) (0)
- Technical Reports: An Undulator Beamline for Protein Crystallography at the NSLS: Commissioning and Operation of X29 (2005) (0)
- 3.25 – Structural Genomics (2007) (0)
- Pair of canted undulator MX beamlines proposed for NSLS-II (2011) (0)
- Optical and X-Ray Techniques in the Study of Rapid Ligand Binding: A Ligand „Docking“ Site in the Reaction of Mb and Co At 40 K (1987) (0)
- Synchrotron X-ray Footprinting of the Gelsolin Segment-1/Actin Complex (2000) (0)
- DIABETIC CYSTOPATHY IS ASSOCIATED WITH CHANGES IN THE OXIDATIVE STRESS STATUS OF THE BLADDER (2009) (0)
- Abstract 3865: Therapeutic activation of protein phosphatase 2A for the treatment of lung cancer (2016) (0)
- Crystal Structure of Escherichia coli L-arabinose Isomerase (ECAI) complexed with Ribitol (2012) (0)
- Crystal structure of L-Arabinose Isomerase from E.coli (2005) (0)
- A Radical Probe of Antigen Structure and Antigen-Antibody Interactions Using Synchrotron Radiation and Mass Spectrometry (2000) (0)
- Metastable contacts and structural disorder in the estrogen receptor transactivation domain (2018) (0)
- Structural Differences Between Rate States of Carboxyhemoglobin Compounds (1987) (0)
- Study on Conformation Transition of Silk Fibroin by Using FTIR (2001) (0)
- Structural basis for modification of flavonol and naphthol glucoconjugates by Nicotiana tabacum malonyltransferase (NtMaT1) (2012) (0)
- Workshop on biological and chemical applications of exafs spectroscopy (1997) (0)
- Crystal Structure of the Visual Cycle Isomerase RPE65 (2009) (0)
- Comparison of Label Free and 18 O Labeling Mass Spectrometry in Relative Protein Quantification (2009) (0)
- CS10-3. IKKi is required for interleukin 17-dependent signaling associated with neutrophilia and pulmonary inflammation (2011) (0)
- Probing Antigen Structure and Antigen-Antibody Interactions by Synchrotron Radiation and Mass Spectrometry (2001) (0)
- CRYSTAL STRUCTURE OF URACIL-DNA GLYCOSYLASE FROM T. MARITIMA (2003) (0)
- Hydroxyl radical probe of Ca 2+ activated gelsolin structure using synchrotron X-ray radiolysis and mass spectrometry (2002) (0)
- Structural Insights into the Dynamics of the TRPA1 Activation Mechanism (2013) (0)
- Abstract 3217: Identification of mutated peptides/proteins driving cancer phenotype utilizing improved shotgun proteomics and data analysis approaches. (2013) (0)
- MoBaS on Phosphorylation Data (2016) (0)
- Development of a High Throughput X-Ray Footprinting Facility at the Advanced Light Source to Study the Structure and Dynamics of Complex Biological Macromolecules (2014) (0)
- Post-NGS: Interpretation and analysis of next generation sequencing data for basic and translational science (2012) (0)
- X-ray Footprinting Studies on Photoactivation of Bovine Rhodopsin (2009) (0)
- Abstract B124: Drugging the undruggable: development of small molecule activators of protein phosphatase 2A for cancer treatment (2015) (0)
- Abstract 1279: Proteomics signature of long-term versus short-term survival in glioblastoma (2012) (0)
- Assessing collective disease association of multiple genomic loci (2014) (0)
- CRYSTAL STRUCTURE OF THE HUMAN C-TERMINAL CAP1-ADENYLYL CYCLASE ASSOCIATED PROTEIN (2003) (0)
- X-ray Footprinting at Beamline X28C: A National Resource for Studying Macromolecular Structure and Dynamics (2009) (0)
- Constructing Functional Networks of Phosphorylation Sites Using Co-Phosphorylation (2021) (0)
- Response: absence of CCR5 intracellular pools in most CD4 and CD8 T cells (2011) (0)
- Abstract 1616: Phosphoprotein enrichment pathway analysis tools for studying cancer signaling (2014) (0)
- MP1-18 MOLECULAR MECHANISMS AND DYSREGULATED SUB-NETWORKS FOR BLADDER DYSFUNCTION IN TYPE 2 DIABETIC MICE (2014) (0)
- SYNCHROTRON INFRARED SPECTROSCOPY AT NSLS BEAMLINE U2B (2005) (0)
- Session Introduction (2011) (0)
- Detection of structural waters and their role in structural dynamics of rhodopsin activation. (2015) (0)
- Global phosphoproteomics of CCR5-tropic HIV-1 signaling reveals reprogramming of cellular protein production pathways and identifies p70-S6K1 and MK2 as HIV-responsive kinases required for optimal infection of CD4+ T cells (2018) (0)
- Differential Expression of Fibulin Family Proteins in Mechanically Strong vs. Weak Fetal Membrane Fragments (2007) (0)
- Proteomics of early azoxymethane‐induced intestinal tumorigenesis in F344 rats consuming a normal diet. (2013) (0)
- Molecular Networks and Complex Diseases (2012) (0)
- X-ray absorption spectroscopy of B12: structural changes of intermediate states. (1999) (0)
- Infrared Microspectroscopy to Assess Neurodegeneration (2000) (0)
- X-ray absorption and low-temperature optical spectroscopy of coenzyme B-12 (1989) (0)
- 346 Promoter insertion reveals lysine demethylase FBXL11 as a negative regulator of NF-κB (2008) (0)
- Chemokine Protein-3 / CCL 7 Enable It to Function as a Epitopes of Monocyte Chemoattractant Multiple Glycosaminoglycan-binding Molecular Biophysics : (2014) (0)
- Small molecule inhibitors of 15-PGDH exploit a physiologic induced-fit closing system (2023) (0)
- Infrared Absorption Properties of Carbonado-Diamond: Additional Evidence for an Extraterrestrial Origin (2006) (0)
- A New Approach for Nucleic Acid Footprinting Data Analysis (2005) (0)
- Probing the conformation difference between Ca 2+-ATP-actin and Mg 2+-ATP-actin by hydroxyl radicals and mass spectrometry (2002) (0)
- A multipronged footprinting map validates the predicted structure of stress biomarker Neuropeptide Y (NPY) and its binding with novel peptide binders. (2023) (0)
- Abstract PR04: Cancer drug response networks built for comparative cancer pharmacogenomics identifies combination therapies for repositioning (2015) (0)
- Age Association Analysis between Tricarboxylic Acid Metabolites and Neurocognitive Impairment in Persons Living with HIV (2019) (0)
- Acetylcarnitine treatment increases mitochondrial protein‐lysine acetylation and protein expression (2010) (0)
- Discovery of common sequences absent in the human reference genome using pooled samples from next generation sequencing (2014) (0)
- Pairwise protein expression classifier for candidate biomarker discovery for early detection of human disease prognosis (2012) (0)
- Hypo-responsiveness of human alveolar macrophages to IFN-γ is not due to attenuated STAT1 signaling (2023) (0)
- BIOLOGICAL PATHWAYS AND RELATED PROTEIN BIOMARKERS OF CLINICAL PROGRESSION IN EARLY ALZHEIMER’S DISEASE (2018) (0)
- Elucidating lactate oxidase enzyme–biomarker lactate interactions by SAXS, crystallography and X-ray footprinting for developing a real-time stress biosensor (2021) (0)
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