Mark Donowitz

Q: What Schools Are Affiliated With Mark Donowitz

Mark Donowitz is affiliated with the following schools: University of California, Berkeley, Tufts University, Keio University, Stanford University, Cornell University, Johns Hopkins University, University of Naples Federico II

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Mark Donowitz's Degrees

PhD Computer Science Stanford University
Masters Electrical Engineering University of California, Berkeley
Bachelors Computer Engineering University of California, Berkeley

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Mark Donowitz's Published Works

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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

The burden of selected digestive diseases in the United States. (2002) (1462)
TAZ: a novel transcriptional co‐activator regulated by interactions with 14‐3‐3 and PDZ domain proteins (2000) (680)
The protein kinase Akt induces epithelial mesenchymal transition and promotes enhanced motility and invasiveness of squamous cell carcinoma lines. (2003) (648)
Evolutionary origins of eukaryotic sodium/proton exchangers. (2005) (512)
cAMP-mediated inhibition of the epithelial brush border Na+/H+ exchanger, NHE3, requires an associated regulatory protein. (1997) (446)
Molecular physiology of intestinal Na+/H+ exchange. (2005) (362)
Cloning and sequencing of a rabbit cDNA encoding an intestinal and kidney-specific Na+/H+ exchanger isoform (NHE-3). (1992) (322)
Na+/H+ exchanger regulatory factor 2 directs parathyroid hormone 1 receptor signalling (2002) (315)
NHE2 and NHE3 are human and rabbit intestinal brush-border proteins. (1996) (304)
Differential roles of NHERF1, NHERF2, and PDZK1 in regulating CFTR-mediated intestinal anion secretion in mice. (2009) (297)
Human Intestinal Enteroids: a New Model To Study Human Rotavirus Infection, Host Restriction, and Pathophysiology (2015) (265)
A primary human macrophage-enteroid co-culture model to investigate mucosal gut physiology and host-pathogen interactions (2017) (257)
NaCl uptake by the branchial epithelium in freshwater teleost fish: an immunological approach to ion-transport protein localization. (2000) (254)
Akt as a mediator of cell death (2003) (246)
Kinetics and regulation of three cloned mammalian Na+/H+ exchangers stably expressed in a fibroblast cell line. (1993) (245)
SLC9/NHE gene family, a plasma membrane and organellar family of Na⁺/H⁺ exchangers. (2013) (217)
Mammalian Na+/H+ exchanger gene family: structure and function studies. (1995) (216)
Cloning and expression of a rabbit cDNA encoding a serum-activated ethylisopropylamiloride-resistant epithelial Na+/H+ exchanger isoform (NHE-2). (1993) (201)
Human Enteroids/Colonoids and Intestinal Organoids Functionally Recapitulate Normal Intestinal Physiology and Pathophysiology* (2015) (198)
NHERF family and NHE3 regulation (2005) (197)
Regulatory binding partners and complexes of NHE3. (2007) (196)
Functional Coupling of Human Microphysiology Systems: Intestine, Liver, Kidney Proximal Tubule, Blood-Brain Barrier and Skeletal Muscle (2017) (183)
The glycosphingolipid globotriaosylceramide in the metastatic transformation of colon cancer. (2005) (182)
Free radicals and other reactive oxygen metabolites in inflammatory bowel disease: cause, consequence or epiphenomenon? (1992) (177)
Enterohemorrhagic Escherichia coli Reduces Mucus and Intermicrovillar Bridges in Human Stem Cell-Derived Colonoids (2015) (176)
Immunolocalization of ion-transport proteins to branchial epithelium mitochondria-rich cells in the mudskipper (Periophthalmodon schlosseri). (2000) (175)
Polarized distribution of key membrane transport proteins in the rat submandibular gland (1996) (171)
Squalamine inhibits angiogenesis and solid tumor growth in vivo and perturbs embryonic vasculature. (1998) (167)
Human Na(+)/H(+) exchanger isoform 6 is found in recycling endosomes of cells, not in mitochondria. (2002) (164)
Molecular cloning and expression of a cDNA encoding the rabbit ileal villus cell basolateral membrane Na+/H+ exchanger. (1991) (159)
Cloning, tissue distribution, and functional analysis of the human Na+/N+ exchanger isoform, NHE3. (1995) (159)
Arachidonic acid metabolites and their role in inflammatory bowel disease. An update requiring addition of a pathway. (1985) (151)
Human enteroids as an ex-vivo model of host–pathogen interactions in the gastrointestinal tract (2014) (146)
NHERF associations with sodium-hydrogen exchanger isoform 3 (NHE3) and ezrin are essential for cAMP-mediated phosphorylation and inhibition of NHE3. (2000) (146)
The Concise Guide to Pharmacology 2013/14: Overview (2013) (143)
Human Enteroids as a Model of Upper Small Intestinal Ion Transport Physiology and Pathophysiology. (2016) (142)
Structure/function studies of mammalian Na‐H exchangers‐‐an update. (1995) (140)
Differential renal distribution of NHERF isoforms and their colocalization with NHE3, ezrin, and ROMK. (2001) (138)
Ca2+-dependent Inhibition of Na+/H+ Exchanger 3 (NHE3) Requires an NHE3-E3KARP-α-Actinin-4 Complex for Oligomerization and Endocytosis* (2002) (136)
Secretory diarrhoea: mechanisms and emerging therapies (2015) (135)
Functional characteristics of a cloned epithelial Na+/H+ exchanger (NHE3): resistance to amiloride and inhibition by protein kinase C. (1993) (132)
Mutations in TTC37 cause trichohepatoenteric syndrome (phenotypic diarrhea of infancy). (2010) (131)
Na+‐H+ exchanger 3 (NHE3) is present in lipid rafts in the rabbit ileal brush border: a role for rafts in trafficking and rapid stimulation of NHE3 (2001) (128)
Separate C-terminal Domains of the Epithelial Specific Brush Border Na+/H+ Exchanger Isoform NHE3 Are Involved in Stimulation and Inhibition by Protein Kinases/Growth Factors (*) (1995) (128)
Role of lipid rafts in Shiga toxin 1 interaction with the apical surface of Caco-2 cells. (2001) (124)
Glucocorticoid stimulation of ileal Na+ absorptive cell brush border Na+/H+ exchange and association with an increase in message for NHE-3, an epithelial Na+/H+ exchanger isoform. (1993) (120)
Ca2+ and cyclic AMP in regulation of intestinal Na, K, and Cl transport. (1986) (119)
Brush Border Phosphatidylinositol 3-Kinase Mediates Epidermal Growth Factor Stimulation of Intestinal NaCl Absorption and Na/H Exchange (*) (1996) (112)
Downregulation of sodium transporters and NHERF proteins in IBD patients and mouse colitis models: Potential contributors to IBD‐associated diarrhea (2009) (112)
Glucagon secretion in acute and chronic pancreatitis. (1975) (111)
Evaluation of patients with chronic diarrhea. (1995) (108)
NHE3 regulatory complexes (2009) (103)
Squalamine, a novel cationic steroid, specifically inhibits the brush-border Na+/H+exchanger isoform NHE3. (1999) (102)
Reduced sodium/proton exchanger NHE3 activity causes congenital sodium diarrhea. (2015) (102)
cGMP Inhibition of Na+/H+ Antiporter 3 (NHE3) Requires PDZ Domain Adapter NHERF2, a Broad Specificity Protein Kinase G-anchoring Protein* (2005) (100)
Human mini-guts: new insights into intestinal physiology and host–pathogen interactions (2016) (100)
Lysophosphatidic acid stimulates the intestinal brush border Na(+)/H(+) exchanger 3 and fluid absorption via LPA(5) and NHERF2. (2010) (99)
A paradox of transcriptional and functional innate interferon responses of human intestinal enteroids to enteric virus infection (2017) (98)
Calcium dependence of serotonin-induced changes in rabbit ileal electrolyte transport. (1980) (97)
Duodenum Intestine-Chip for preclinical drug assessment in a human relevant model (2020) (97)
Ca2+-dependent inhibition of NHE3 requires PKC alpha which binds to E3KARP to decrease surface NHE3 containing plasma membrane complexes. (2003) (94)
Macropinocytosis in Shiga toxin 1 uptake by human intestinal epithelial cells and transcellular transcytosis. (2009) (92)
Corrigendum: Functional Coupling of Human Microphysiology Systems: Intestine, Liver, Kidney Proximal Tubule, Blood-Brain Barrier and Skeletal Muscle (2017) (92)
Pharmacological Properties of N-(3,5-Diamino-6-chloropyrazine-2-carbonyl)-N′-4-[4-(2,3-dihydroxypropoxy)phenyl]butyl-guanidine Methanesulfonate (552-02), a Novel Epithelial Sodium Channel Blocker with Potential Clinical Efficacy for Cystic Fibrosis Lung Disease (2008) (88)
Effect of serotonin treatment on intestinal transport in the rabbit. (1977) (88)
Ca2+ in the control of active intestinal Na and Cl transport: involvement in neurohumoral action. (1983) (87)
D-glucose acts via sodium/glucose cotransporter 1 to increase NHE3 in mouse jejunal brush border by a Na+/H+ exchange regulatory factor 2-dependent process. (2011) (87)
Lysophosphatidic Acid Stimulates Brush Border Na+/H+ Exchanger 3 (NHE3) Activity by Increasing Its Exocytosis by an NHE3 Kinase A Regulatory Protein-dependent Mechanism* (2003) (86)
Na+/H+ Exchanger NHE3 Activity and Trafficking Are Lipid Raft-dependent* (2006) (85)
Genome-Wide Analysis Reveals the Vacuolar pH-Stat of Saccharomyces cerevisiae (2011) (84)
Quantitative contribution of NHE2 and NHE3 to rabbit ileal brush-border Na+/H+ exchange. (1998) (81)
Na+/H+ exchanger-2 is an O-linked but not an N-linked sialoglycoprotein. (1994) (80)
Transepithelial resistance can be regulated by the intestinal brush-border Na(+)/H(+) exchanger NHE3. (2000) (80)
The roles of PDZ-containing proteins in PLC-β-mediated signaling (2001) (77)
Effect of dioctyl sodium sulfosuccinate on colonic fluid and electrolyte movement. (1975) (75)
CFTR protein expression in primary and cultured epithelia. (1992) (75)
Genistein and tyrphostin 47 stimulate CFTR-mediated Cl- secretion in T84 cell monolayers. (1995) (74)
Basic Fibroblast Growth Factor Stimulates Surface Expression and Activity of Na+/H+ Exchanger NHE3 via Mechanism Involving Phosphatidylinositol 3-Kinase* (2000) (74)
Regulation of Tight Junction Resistance in T84 Monolayers by Elevation in Intracellular Ca2+: A Protein Kinase C Effect (1996) (73)
Effect of serotonin on active electrolyte transport in rabbit ileum, gallbladder, and colon. (1980) (73)
The Na+/H+ exchange isoform NHE3 regulates basal canine ileal Na+ absorption in vivo. (1997) (73)
Membrane‐limited expression and regulation of Na+‐H+ exchanger isoforms by P2 receptors in the rat submandibular gland duct (1998) (72)
Tissue-specific Regulation of Sodium/Proton Exchanger Isoform 3 Activity in Na+/H+ Exchanger Regulatory Factor 1 (NHERF1) Null Mice (2007) (71)
Inhibition of sodium/hydrogen exchanger 3 in the gastrointestinal tract by tenapanor reduces paracellular phosphate permeability (2018) (71)
The NHE3 Juxtamembrane Cytoplasmic Domain Directly Binds Ezrin: Dual Role In NHE3 Trafficking and Movement In the Brush Border (2006) (70)
The lateral mobility of NHE3 on the apical membrane of renal epithelial OK cells is limited by the PDZ domain proteins NHERF1/2, but is dependent on an intact actin cytoskeleton as determined by FRAP (2004) (70)
Defective jejunal and colonic salt absorption and alteredNa+/H+ exchanger 3 (NHE3) activity in NHE regulatory factor 1 (NHERF1) adaptor protein-deficient mice (2009) (69)
Regulation of the Epithelial Brush Border Na+/H+ Exchanger Isoform 3 Stably Expressed in Fibroblasts by Fibroblast Growth Factor and Phorbol Esters Is Not through Changes in Phosphorylation of the Exchanger* (1997) (68)
Entamoeba histolytica causes intestinal secretion: role of serotonin. (1983) (68)
Prevention and reversal of cholera enterotoxin-induced intestinal secretion by methylprednisolone induction of Na+-K+-ATPase. (1976) (68)
Akt2, phosphatidylinositol 3-kinase, and PTEN are in lipid rafts of intestinal cells: role in absorption and differentiation. (2004) (68)
Carbachol regulation of rabbit ileal brush border Na+–H+ exchanger 3 (NHE3) occurs through changes in NHE3 trafficking and complex formation and is Src dependent (2004) (67)
Farnesoid X receptor agonists attenuate colonic epithelial secretory function and prevent experimental diarrhoea in vivo (2013) (66)
Na(+)/H(+) exchanger 3 is in large complexes in the center of the apical surface of proximal tubule-derived OK cells. (2002) (66)
Hyperosmolarity inhibits the Na+/H+ exchanger isoforms NHE2 and NHE3: an effect opposite to that on NHE1. (1996) (64)
Kinetics and regulation of a polarized Na(+)-H+ exchanger from Caco-2 cells, a human intestinal cell line. (1991) (63)
A new look at laxative action. (1975) (62)
Na+/H+ Exchanger Isoform 2 (NHE2) is Expressed in the Apical Membrane of the Medullary Thick Ascending Limb (1997) (61)
Rabbit ileal villus cell brush border Na+/H+ exchange is regulated by Ca2+/calmodulin-dependent protein kinase II, a brush border membrane protein. (1990) (59)
Elevated intracellular Ca2+ acts through protein kinase C to regulate rabbit ileal NaCl absorption. Evidence for sequential control by Ca2+/calmodulin and protein kinase C. (1989) (58)
Dopamine stimulation of active Na and Cl absorption in rabbit ileum: interaction with alpha 2-adrenergic and specific dopamine receptors. (1982) (57)
C-terminal domains of Na(+)/H(+) exchanger isoform 3 are involved in the basal and serum-stimulated membrane trafficking of the exchanger. (2000) (57)
ClC-5: role in endocytosis in the proximal tubule. (2005) (56)
Cystic Fibrosis Transmembrane Conductance Regulator Activation Is Reduced in the Small Intestine of Na+/H+ Exchanger 3 Regulatory Factor 1 (NHERF-1)- but Not NHERF-2-deficient Mice* (2007) (56)
Casein kinase 2 binds to the C terminus of Na+/H+ exchanger 3 (NHE3) and stimulates NHE3 basal activity by phosphorylating a separate site in NHE3. (2008) (55)
Constitutively Active Phosphatidylinositol 3-Kinase and AKT Are Sufficient to Stimulate the Epithelial Na+/H+ Exchanger 3* (2001) (55)
Half-lives of plasma membrane Na(+)/H(+) exchangers NHE1-3: plasma membrane NHE2 has a rapid rate of degradation. (2001) (52)
Immunolocalisation of sodium/proton exchanger-like proteins in the gills of elasmobranchs. (2002) (52)
Colo-rectal biopsy in inflammatory bowel disease. (1977) (52)
Structure/function studies of the epithelial isoforms of the mammalian Na+/H+ exchanger gene family (1993) (51)
Short‐Term Regulation of NHE3 by EGF and Protein Kinase C but Not Protein Kinase A Involves Vesicle Trafficking in Epithelial Cells and Fibroblasts (2000) (50)
The attrition of young physician-scientists: problems and potential solutions. (2007) (50)
Na+/H+ exchangers (NHE1-3) have similar turnover numbers but different percentages on the cell surface. (1999) (48)
Calcium dependence of basal electrolyte transport in rabbit ileum. (1982) (47)
Effect of enterotoxins of Vibrio cholerae, Escherichia coli, and Shigella dysenteriae type 1 on fluid and electrolyte transport in the colon. (1976) (47)
NHERF1 and NHERF2 are necessary for multiple but usually separate aspects of basal and acute regulation of NHE3 activity. (2011) (47)
Serum regulates Na+/H+ exchange in Caco-2 cells by a mechanism which is dependent on F-actin. (1992) (46)
Carbachol- and elevated Ca(2+)-induced translocation of functionally active protein kinase C to the brush border of rabbit ileal Na+ absorbing cells. (1991) (46)
Epithelial WNT Ligands Are Essential Drivers of Intestinal Stem Cell Activation. (2018) (46)
Human duodenal mucosal brush border Na(+)/H(+) exchangers NHE2 and NHE3 alter net bicarbonate movement. (2001) (46)
Functional significance of intestinal Na+-K+-ATPase: in vivo ouabain inhibition. (1978) (44)
Human enteroids: preclinical models of non-inflammatory diarrhea (2013) (44)
A polarized salivary cell monolayer useful for studying transepithelial fluid movement in vitro (1998) (44)
The Spatial Organization of Proton and Lactate Transport in a Rat Brain Tumor (2011) (43)
Effects of phorbol esters on sodium and chloride transport in rat colon. (1986) (43)
In birds, NHE2 is major brush-border Na+/H+ exchanger in colon and is increased by a low-NaCl diet. (1998) (41)
Cyclic GMP Kinase II (cGKII) Inhibits NHE3 by Altering Its Trafficking and Phosphorylating NHE3 at Three Required Sites (2014) (41)
Development of an endogenous epithelial Na+/H+exchanger (NHE3) in three clones of Caco-2 cells. (1999) (41)
The Contributions of Human Mini-Intestines to the Study of Intestinal Physiology and Pathophysiology. (2017) (40)
Pathogenesis of Shigella diarrhea. XVI. Selective targetting of Shiga toxin to villus cells of rabbit jejunum explains the effect of the toxin on intestinal electrolyte transport. (1989) (40)
Leu143 in the putative fourth membrane spanning domain is critical for amiloride inhibition of an epithelial Na+/H+ exchanger isoform (NHE-2). (1993) (40)
Na(+)/H(+) exchanger NHE3 has 11 membrane spanning domains and a cleaved signal peptide: topology analysis using in vitro transcription/translation. (2000) (40)
Freeze-thaw and high-voltage discharge allow macromolecule uptake into ileal brush-border vesicles. (1987) (39)
Hyperthermia effects on cytosolic [Ca2+]: analysis at the single cell level by digitized imaging microscopy and cell survival. (1991) (39)
Challenges in IBD Research: Preclinical Human IBD Mechanisms. (2019) (38)
Regulation of the rabbit ileal brush-border Na+/H+ exchanger by an ATP-requiring Ca++/calmodulin-mediated process. (1988) (38)
Role of acid/base homeostasis in the suppression of apoptosis in haemopoietic cells by v-Abl protein tyrosine kinase. (1997) (38)
NHERF2 is necessary for basal activity, second messenger inhibition, and LPA stimulation of NHE3 in mouse distal ileum. (2011) (38)
Loss of PDZ‐adaptor protein NHERF2 affects membrane localization and cGMP‐ and [Ca2+]‐ but not cAMP‐dependent regulation of Na+/H+ exchanger 3 in murine intestine (2010) (37)
Discovery and development of antisecretory drugs for treating diarrheal diseases. (2014) (37)
Proteome of murine jejunal brush border membrane vesicles. (2007) (37)
Effect of Shigella enterotoxin on electrolyte transport in rabbit ileum. (1975) (37)
Effect of extracellular calcium depletion on epithelial structure and function in rabbit ileum: a model for selective crypt or villus epithelial cell damage and suggestion of secretion by villus epithelial cells. (1982) (37)
Trifluoperazine reversal of secretory diarrhea in pancreatic cholera. (1980) (37)
Neural control of acid-induced serotonin release from rabbit duodenum. (1983) (36)
Enterotoxigenic Escherichia coli–blood group A interactions intensify diarrheal severity (2018) (36)
Reversible sulfasalazine-induced granulomatous hepatitis. (1981) (36)
Translating molecular physiology of intestinal transport into pharmacologic treatment of diarrhea: stimulation of Na+ absorption. (2014) (36)
Molecular Properties, Kinetics and Regulation of Mammalian Na+/H+ Exchangers (1994) (36)
The neurohumoral secretagogues carbachol, substance P and neurotensin increase Ca++ influx and calcium content in rabbit ileum. (1982) (36)
THE EPITHELIAL BRUSH BORDER Na+/H+ EXCHANGER NHE3 ASSOCIATES WITH THE ACTIN CYTOSKELETON BY BINDING TO EZRIN DIRECTLY AND VIA PDZ DOMAIN‐CONTAINING Na+/H+ EXCHANGER REGULATORY FACTOR (NHERF) PROTEINS (2008) (36)
Extrahepatic portal venous thrombosis: frequent recognition of associated diseases. (1985) (35)
Benzopyrimido‐pyrrolo‐oxazine‐dione CFTR inhibitor (R)‐BPO‐27 for antisecretory therapy of diarrheas caused by bacterial enterotoxins (2017) (35)
Chimeric Na+/H+ exchangers: an epithelial membrane-bound N-terminal domain requires an epithelial cytoplasmic C-terminal domain for regulation by protein kinases. (1995) (35)
The transport of an intact oligopeptide across adult mammalian jejunum. (1986) (35)
Physical and genetic mapping of a human apical epithelial Na+/H+ exchanger (NHE3) isoform to chromosome 5p15.3. (1993) (34)
Asymmetric signal transduction in polarized ileal Na(+)-absorbing cells: carbachol activates brush-border but not basolateral-membrane PIP2-PLC and translocates PLC-gamma 1 only to the brush border. (1996) (34)
Molecular Basis and Differentiation-Associated Alterations of Anion Secretion in Human Duodenal Enteroid Monolayers (2018) (34)
Propranolol prevention of cholera enterotoxin-induced intestinal secretion in the rat. (1979) (34)
Ileal microvillar protein villin is tyrosine-phosphorylated and associates with PLC-gamma1. Role of cytoskeletal rearrangement in the carbachol-induced inhibition of ileal NaCl absorption. (1997) (34)
Intestinal enteroids/organoids: A novel platform for drug discovery in inflammatory bowel diseases (2019) (33)
NHERF3 (PDZK1) Contributes to Basal and Calcium Inhibition of NHE3 Activity in Caco-2BBe Cells* (2009) (33)
Drug therapy for diarrheal diseases: a look ahead. (1986) (33)
Effect of dopamine and bromocriptine on rat ileal and colonic transport. Stimulation of absorption arid reversal of cholera toxin-induced secretion (1983) (32)
Role of prostaglandins and calcium in the effects of Entamoeba histolytica on colonic electrolyte transport. (1990) (32)
Ca2+ channel blockers stimulate ileal and colonic water absorption. (1985) (32)
Translational approaches for pharmacotherapy development for acute diarrhea. (2012) (32)
The roles of PDZ-containing proteins in PLC-beta-mediated signaling. (2001) (31)
Two calcium channels in basolateral membranes of rabbit ileal epithelial cells. (1989) (31)
Premarin-induced ischemic colitis. (1994) (30)
Brush-border tyrosine phosphorylation stimulates ileal neutral NaCl absorption and brush-border Na(+)-H+ exchange. (1994) (30)
Does the proteome encode organellar pH? (2006) (30)
Quantitation of Plasma Membrane Expression of a Fusion Protein of Na/H Exchanger NHE3 and Green Fluorescence Protein (GFP) in Living PS120 Fibroblasts (2000) (30)
cAMP Stimulates SLC26A3 Activity in Human Colon by a CFTR-Dependent Mechanism That Does Not Require CFTR Activity (2018) (29)
Fractionation of subcellular membrane vesicles of epithelial and non-epithelial cells by OptiPrep™ density gradient ultracentrifugation. (2014) (29)
Na+/H+ exchange mediates meal-stimulated ileal absorption. (1994) (28)
In birds, NHE2 is major brush-border Na+/H+exchanger in colon and is increased by a low-NaCl diet. (1998) (27)
Fractionation of subcellular membrane vesicles of epithelial and nonepithelial cells by OptiPrep density gradient ultracentrifugation. (2008) (27)
Chloride Channel (Clc)-5 Is Necessary for Exocytic Trafficking of Na+/H+ Exchanger 3 (NHE3)* (2011) (27)
Carbachol-induced cytosolic free Ca2+ increases in T84 colonic cells seen by microfluorimetry. (1989) (26)
PTH transiently increases the percent mobile fraction of Npt2a in OK cells as determined by FRAP. (2009) (26)
Shiga toxin 1 interaction with enterocytes causes apical protein mistargeting through the depletion of intracellular galectin-3. (2010) (25)
Elevated Intracellular Calcium Stimulates NHE3 Activity by an IKEPP (NHERF4) Dependent Mechanism (2008) (25)
Two Histidine Residues in the Juxta-Membrane Cytoplasmic Domain of Na+/H+ Exchanger Isoform 3 (NHE3) Determine the Set Point (2003) (25)
Regulation of Intestinal Electroneutral Sodium Absorption and the Brush Border Na+/H+ Exchanger by Intracellular Calcium (2009) (25)
Microfluidics platform for measurement of volume changes in immobilized intestinal enteroids. (2014) (24)
Myosin VI mediates the movement of NHE3 down the microvillus in intestinal epithelial cells (2014) (24)
Sorting nexin 27 regulates basal and stimulated brush border trafficking of NHE3 (2015) (24)
Effects of spironolactone and amiloride on corticosteroid-induced changes in colonic function. (1981) (24)
Gastrointestinal microphysiological systems (2017) (24)
Mechanical Stimuli Affect Escherichia coli Heat-Stable Enterotoxin-Cyclic GMP Signaling in a Human Enteroid Intestine-Chip Model (2019) (24)
NHE2 contains subdomains in the COOH terminus for growth factor and protein kinase regulation. (1999) (24)
Phospholipase C-γ Binds Directly to the Na+/H+ Exchanger 3 and Is Required for Calcium Regulation of Exchange Activity* (2009) (24)
The Zn2+-sensing receptor, ZnR/GPR39, upregulates colonocytic Cl- absorption, via basolateral KCC1, and reduces fluid loss. (2017) (23)
Mucus layer modeling of human colonoids during infection with enteroaggragative E. coli (2020) (23)
Studies on role of calmodulin in Ca2+ regulation of rabbit ileal Na and Cl transport. (1985) (23)
Urine electrolyte, mineral, and protein excretion in NHERF-2 and NHERF-1 null mice. (2008) (23)
Ca2+-calmodulin-, cyclic AMP- and cyclic GMP-induced phosphorylation of proteins in purified microvillus membranes of rabbit ileum. (1984) (23)
Lysophosphatidic acid induces exocytic trafficking of Na(+)/H(+) exchanger 3 by E3KARP-dependent activation of phospholipase C. (2004) (22)
NHE3 mobility in brush borders increases upon NHERF2-dependent stimulation by lyophosphatidic acid (2010) (22)
Effects of methylprednisolone on electrolyte transport by in vitro rat ileum. (1981) (22)
Pleiotropic ZIP8 A391T implicates abnormal manganese homeostasis in complex human disease (2020) (22)
Acid and isoproterenol cause serotonin release by acting on opposite surfaces of duodenal mucosa. (1984) (21)
Current Concepts of Laxative Action: Mechanisms by which Laxatives Increase Stool Water (1979) (20)
Latrunculin B facilitates Shiga toxin 1 transcellular transcytosis across T84 intestinal epithelial cells. (2008) (20)
The mammalian Na+/H+ exchanger gene family--initial structure/function studies. (1993) (20)
Catching the Zebra: Clinical Pearls and Pitfalls for the Successful Diagnosis of Zollinger–Ellison Syndrome (2017) (19)
Calmodulin Kinase II Constitutively Binds, Phosphorylates, and Inhibits Brush Border Na+/H+ Exchanger 3 (NHE3) by a NHERF2 Protein-dependent Process* (2012) (19)
Pancreatic cholera syndrome due to a vasoactive intestinal polypeptide-producing tumor: further insights into the pathophysiology. (1988) (19)
Role of brush border Na+/H+ exchange in canine ileal absorption (1996) (19)
Ca2+- and calmodulin-dependent protein phosphorylation in rat lacrimal gland. (1982) (19)
AKT and GSK-3 Are Necessary for Direct Ezrin Binding to NHE3 as Part of a C-terminal Stimulatory Complex (2014) (19)
Jejunal fluid and electrolyte secretion in carcinoid syndrome (1975) (19)
NHERF2/NHERF3 Protein Heterodimerization and Macrocomplex Formation Are Required for the Inhibition of NHE3 Activity by Carbachol* (2014) (18)
Chapter 12 Molecular physiology of mammalian epithelial Na+/H+ exchangers NHE2 and NHE3 (2000) (18)
Characterization of the synergistic interaction of Escherichia coli heat-stable toxin and carbachol. (1991) (18)
Differential Association of the Na+/H+ Exchanger Regulatory Factor (NHERF) Family of Adaptor Proteins with the Raft- and the Non-Raft Brush Border Membrane Fractions of NHE3 (2013) (18)
Alterations in the proteome of the NHERF1 knockout mouse jejunal brush border membrane vesicles. (2010) (18)
Erratum: A primary human macrophage-enteroid co-culture model to investigate mucosal gut physiology and host-pathogen interactions (2017) (18)
Cyclic nucleotide‐dependent enzyme secretion in the rat lacrimal gland. (1984) (18)
Abnormal secretagogue-induced intracellular free Ca2+ regulation in cystic fibrosis nasal epithelial cells. (1992) (17)
Lysophosphatidic acid stimulation of NHE3 exocytosis in polarized epithelial cells occurs with release from NHERF2 via ERK-PLC-PKCδ signaling. (2014) (17)
New melanocortin-like peptide of E. coli can suppress inflammation via the mammalian melanocortin-1 receptor (MC1R): possible endocrine-like function for microbes of the gut (2017) (16)
Cholera toxin inhibits SNX27-retromer-mediated delivery of cargo proteins to the plasma membrane (2018) (16)
Elevated Calcium Acutely Regulates Dynamic Interactions of NHERF2 and NHE3 Proteins in Opossum Kidney (OK) Cell Microvilli* (2011) (16)
Effect of Senokot on rat intestinal electrolyte transport. Evidence of Ca++ dependence. (1984) (16)
Molecular Studies of Members of the Mammalian Na+/H+ Exchanger Gene Family (1996) (16)
Age-related loss of nongoblet crypt cells parallels decreased secretion in rabbit descending colon. (1988) (16)
Use of organoids to study regenerative responses to intestinal damage. (2019) (16)
Mild chronic watery diarrhea-hypokalemia syndrome associated with pancreatic islet cell hyperplasia. Elevated plasma and tissue levels of gastric inhibitory polypeptide and successful management with nicotinic acid. (1979) (16)
Gastrointestinal transport : molecular physiology (2001) (16)
Electrolyte transport in piglets infected with transmissible gastroenteritis virus (1991) (16)
NHE3 Activity Is Dependent on Direct Phosphoinositide Binding at the N Terminus of Its Intracellular Cytosolic Region* (2010) (16)
Elevated intraluminal pressure alters rabbit small intestinal transport in vivo. (1982) (16)
Calcium and calmodulin‐dependent protein phosphorylation in rabbit ileum (1981) (16)
Mechanism of fluid and electrolyte secretion in the germ-free rat cecum (1979) (15)
Role of calcium and calmodulin in the regulation of the rabbit ileal brush-border membrane Na+/H+ antiporter (1989) (15)
Role of calcium in cholinergic stimulation of lacrimal gland protein secretion. (1985) (15)
Effects of calcium antagonist TMB-8 on active Na and Cl transport in rabbit ileum. (1986) (15)
Enterohemorrhagic E. coli (EHEC)—Secreted Serine Protease EspP Stimulates Electrogenic Ion Transport in Human Colonoid Monolayers (2018) (15)
cAMP-mediated inhibition of the epithelial brush border NayH exchanger, NHE3, requires an associated regulatory protein (sodium–hydrogen antiporterypH regulationysignal transductionyNa1 absorption) (1997) (15)
Magnesium-induced diarrhea and new insights into the pathobiology of diarrhea. (1991) (14)
Intestinal filtration-secretion due to increased intraluminal pressure in rabbits. (1982) (14)
NHERF2 Protein Mobility Rate Is Determined by a Unique C-terminal Domain That Is Also Necessary for Its Regulation of NHE3 Protein in OK Cells* (2013) (14)
NHERF2 increases platelet-derived growth factor-induced proliferation through PI-3-kinase/Akt-, ERK-, and Src family kinase-dependent pathway. (2004) (14)
Refractory lymphocytic enterocolitis and tumor necrosis factor antagonist therapy. (2010) (13)
DIABETES WITHOUT GLUCAGON (1976) (13)
Induction of the metal transporter ZIP8 by interferon gamma in intestinal epithelial cells: Potential role of metal dyshomeostasis in Crohn's disease. (2019) (13)
Challenges in IBD Research: Novel Technologies. (2019) (13)
The NHE3 Juxtamembrane Cytoplasmic Domain Directly Binds Ezrin: Dual Role in NHE3 Trafﬁcking and Mobility in the Brush Border (2006) (13)
Phenylquinoxalinone CFTR activator as potential prosecretory therapy for constipation (2017) (13)
Effects of galanin on short circuit current and electrolyte transport in rabbit ileum (1994) (13)
Identification of PTH-responsive Na/H-exchanger isoforms in a rabbit proximal tubule cell line (RKPC-2) (1993) (13)
Inhibition of transport processes of intestinal segments following augmentation enterocystoplasty in rats. (1996) (13)
Dantrolene and basal ileal sodium and chloride transport: involvement of calcium stores. (1983) (13)
Enteric neural pathways inhibitory to rabbit duodenal serotonin release. (1984) (12)
Magnesium Hydroxide: New Insights Into the Mechanism of its Laxative Effect and the Potential Involvement of Prostaglandin E2 (1992) (12)
Patients' perspectives on the derivation and use of organoids (2021) (12)
Increased tear secretion in pancreatic cholera: a newly recognized symptom in an experiment of nature. (1988) (12)
Fluid Shear Stress Enhances Differentiation of Jejunal Human Enteroids in Intestine-Chip. (2020) (12)
Effect of altered intestinal water transport on rabbit ileal blood flow. (1979) (12)
Identifying the localization and exploring a functional role for Gprc5c in the kidney (2017) (12)
Both NHERF3 and NHERF2 are necessary for multiple aspects of acute regulation of NHE3 by elevated Ca2+, cGMP, and lysophosphatidic acid. (2018) (12)
Phosphodiesterase 5 (PDE5) restricts intracellular cGMP accumulation during enterotoxigenic Escherichia coli infection (2020) (11)
Quantitative contribution of NHE 2 and NHE 3 to rabbit ileal brush-border Na 1 / H 1 exchange (1998) (11)
L-Glutamine in intestinal sodium absorption: lessons for physiology, pathobiology, and therapy for diarrhea. (1994) (11)
Gastrointestinal Inﬂuences on Hydrogen Ion Balance (2005) (11)
Methylprednisolone stimulation of guanylate cyclase activity in rat small intestinal mucosa: Possible role in electrolyte transport (1981) (11)
G protein-coupled receptors in gastrointestinal physiology. III. Asymmetry in plasma membrane signal transduction: lessons from brush-border Na+/H+ exchangers. (1998) (11)
Insulin-Like Growth Factor 1 (IGF-1) Enhances the Protein Expression of CFTR (2013) (11)
Current and potential future applications of human stem cell models in drug development. (2020) (10)
Regulation of the transfected Na+/H+-exchanger NHE3 in MDCK cells by vasotocin (1997) (10)
Phosphorylation of NHE3-S719 regulates NHE3 activity through the formation of multiple signaling complexes (2017) (10)
PLC-γ directly binds activated c-Src, which is necessary for carbachol-mediated inhibition of NHE3 activity in Caco-2/BBe cells. (2013) (10)
Significance of Abnormal Rabbit Ileal Histology in the Pathogenesis of Diarrhea (1979) (9)
Effect of dopamine and bromocriptine on rat ileal and colonic transport. Stimulation of absorption and reversal of cholera toxin-induced secretion. (1983) (9)
Coming out of the NHERF family (2005) (9)
Nonsynonymous single nucleotide polymorphisms of NHE3 differentially decrease NHE3 transporter activity. (2015) (9)
The NHERF2 sequence adjacent and upstream of the ERM-binding domain affects NHERF2–ezrin binding and dexamethasone stimulated NHE3 activity (2015) (9)
Epithelial WNT2B and Desert Hedgehog Are Necessary for Human Colonoid Regeneration after Bacterial Cytotoxin Injury (2018) (8)
Pharmacotherapy of diarrheal diseases: an approach based on physiologic principles. (1984) (8)
Pancreatic insufficiency and congenital rubella syndrome. (1975) (8)
Chronic Inflammation in Ulcerative Colitis Causes Long-Term Changes in Goblet Cell Function (2021) (8)
NHE2 contains subdomains in the COOH terminus for growth factor and protein kinase regulation. (1999) (7)
Ca2+ channel blockers interact with alpha 2-adrenergic receptors in rabbit ileum. (1988) (7)
NHERF3 is Necessary for E. coli Heat Stable Enterotoxin (ST)-induced Inhibition of NHE3 - Differences in Signaling in Mouse Small Intestine and Caco-2 Cells. (2019) (7)
Pathophysiological mechanisms of diarrhoeal diseases: diverse aetiologies and common mechanisms. (1983) (7)
PDZ domain-dependent regulation of NHE3 protein by both internal Class II and C-terminal Class I PDZ-binding motifs (2017) (7)
Chloroquine stimulates absorption and inhibits secretion of ileal water and electrolytes. (1982) (6)
Organoid-derived Duodenum Intestine-Chip for preclinical drug assessment in a human relevant system (2019) (6)
Suggestion of a role for calmodulin and phosphorylation in regulation of rabbit ileal electrolyte transport: effects of promethazine. (1986) (6)
Ca2+ - and cAMP-induced protein phosphorylation in lacrimal gland basolateral membranes. (1988) (6)
Secretory hormones of Entamoeba histolytica. (1985) (6)
Inhibition of CFTR‐mediated intestinal chloride secretion as potential therapy for bile acid diarrhea (2019) (5)
Uncoupling of phospholipase C from receptor regulation of [Ca2+]i in T84 colonic cells by prolonged exposure to phorbol dibutyrate. (1991) (5)
Vanishing pancreatic calcifications. A nonspecific finding in chronic pancreatitis. (1974) (5)
Cytosol free Ca++ in the regulation of active intestinal Na and Cl transport. (1984) (5)
Effect of cycloheximide on corticosteroid-induced changes in colonic function. (1982) (5)
Alterations in the proteome of the NHERF2 knockout mouse jejunal brush border membrane vesicles. (2011) (5)
No effect of propranolol on chronic diarrhea. (1979) (5)
Differential effects of PDZ-Adapterprotein NHERF1, E3KARP and PDZK1 knockout on the regulation of NHE3 transport activity in native murine colonic epithelium (2006) (5)
Alterations in the proteome of the NHERF 1 knockout mouse jejunal brush border membrane vesicles (2010) (5)
Pancreatic ascites. (1974) (5)
Effect of chronic elevation of blood serotonin on intestinal transport (1976) (4)
Erratum: cAMP-mediated inhibition of the epithelial brush border NA+/H+ exchanger, NHE3, requires an associated regulatory protein (Proceedings of the National Academy of Sciences of the United States of America (April 1, 1997) 94 (3010-3015)) (1997) (4)
Small intestinal and colonic linked sodium chloride absorption. New understanding of distribution and regulation. (1987) (4)
Calcium/calmodulin dependent protein kinase II constitutively binds and regulates the ileal BB Na+/H+ exchanger NHE3 (2003) (4)
Factors and molecular mechanisms involved in the regulation of chicken colonic luminal membrane Na(+)-linked transport systems. (1996) (4)
Regulatory mechanisms of cloned Na+/H+ exchangers involve change in the amount of plasma membrane exchanger: Use of cell surface biotinylation (1998) (4)
Loss of PI3-kinase activity of inositol polyphosphate multikinase impairs PDK1-mediated AKT activation, cell migration and intestinal homeostasis (2020) (4)
730 Cyclic GMP Kinase II (CKII) Inhibits NHE3 by Affecting Trafficking via Phosphorylating NHE3 At Three Sites: Identification of a Multifunctional Phosphorylation Site (2013) (4)
Protein phosphorylation and the control of intestinal electrolyte transport. (1984) (3)
SARS-COV-2 induced Diarrhea is inflammatory, Ca2+ Dependent and involves activation of calcium activated Cl channels (2021) (3)
E3KARP (NHE3 kinase a anchoring protein) is necessary for cGMP regulation of NHE3: Demonstration of a plasma membrane signaling complex containing NHE3, E3KARP, and cGMP kinase II (2001) (3)
4 A Peptide Mimicking the NHE3 C-Terminus Stimulates Basal and Blocks CA2+ and cAMP Inhibition of NHE3 Activity, and Prevents Cholera Toxin-Induced Mouse Jejunal Fluid Accumulation: Potential Role as Drug Therapy for Diarrhea (2012) (3)
Ileal Microvillar Protein Villin Is Tyrosine-phosphorylated and Associates with PLC-γ1 (1997) (3)
A common NHE3 single-nucleotide polymorphism has normal function and sensitivity to regulatory ligands. (2017) (3)
cGMP-dependent kinase 2, Na+/H+ regulatory factor 2, and Na+/H+ exchanger isoform 3 assemble within lipid rafts in murine small intestinal brush border membrane (2013) (3)
Serotonin (5HT)-induced ileal secretion: Active electrolyte secretion which is calcium dependent (1979) (3)
Quantitative contribution of NHE2 and NHE3 to rabbit ileal brush-border Na+/H+exchange. (1998) (3)
Cholinergic-induced anion secretion in murine jejunal enteroids involves synergy between muscarinic and nicotinic pathways. (2020) (3)
541 Rotavirus Infection in Patients Is Associated With Altered Trafficking of Apical Membrane Transport Proteins (2016) (3)
Methylprednisolone stimulation of guanylate cyclase activity in rat ileal mucosa (1978) (3)
Relation between enteric hormones and intestinal function in the WDHA syndrome (1978) (3)
A NHE3-related pseudogene is on human chromosome 10; the functional gene maps to 5p15.3. (1996) (3)
Identification of Intestinal NaCl Absorptive-Anion Secretory Cells: Potential Functional Significance (2022) (3)
Small intestinal and colonic linked sodium chloride absorption (1987) (2)
Use of Human Tissue Stem Cell-Derived Organoid Cultures to Model Enterohepatic Circulation. (2021) (2)
TMEM16A and NHERF1 Regulate Ca2+ and cAMP Stimulated Cl‐ Secretion in Murine Colon (2012) (2)
749 Nherf2 Is Necessary for Basal and All Second Messenger Regulation of NHE3 Activity in Intact Mouse Ileal Na Absorptive Cells (2008) (2)
[Ca2+]i independent mitogenesis in cultured human fibroblasts revealed by single cell microfluorimetry. (1989) (2)
Enterotoxigenic E. Coli (ETEC) Pathogenesis Modeled in Human Enteroid Monolayers Demonstrates MRP-Related Cyclic Nucleotide Secretion (2017) (2)
Effect of methylprednisolone treatment on ion transport in rat ileum in vitro (1977) (2)
266 NHE3 IS A DRUG TARGET FOR TREATING DIARRHE; A NOVEL PEPTIDE STIMULATES NHE3 ACTIVITY, PREVENTS CAMP, CGMP AND CA2+ INHIBITION OF NHE3 AND PREVENTS CHOLERA TOXIN AND E. COLI STABLE ENTEROTOXIN FLUID SECRETION. (2021) (2)
Methylprednisolone stimulation of guanylate cyclase activity in rat small intestinal mucosa: possible role in electrolyte transport. (1981) (2)
110 Missense Mutations of SLC9A3 in Patients With Congenital Sodium Diarrhea Are Associated With Reduced Na+/H+ Exchanger 3 (NHE3) Activity: Identification of the Cause of the Phenotype (2015) (2)
Squalamine, a novel cationic steroid, specifically inhibits the brush-border Na+/H+ exchanger isoform NHE3. (1999) (2)
The epithelial brush-border Na/H Exchanger NHE3 associates with the actin cytoskeleton by binding to ezrin directly and via PDZ domain containing NHERF proteins (2007) (2)
S1770 Proteome of the Small Intestinal Brush Border of the NHERF1 Knock Out Mouse: Up Regulation of Transporters and Pro-Proliferation Molecules (2008) (2)
The Ethics of Living-Donor Liver Transplantation (2007) (2)
Promethazine stimulates NaCl absorption and inhibits Ca++-calmodulin-dependent phosphorylation (P) in rabbit ileum at the same low concentrations suggesting a role for P in NaCl transport (1985) (2)
Ileal brush border actin-binding protein villin associates with the brush border sodium-hydrogen exchanger, NHE3 (1998) (2)
Towards understanding mechanisms underlying EHEC-induced transcellular transport of nano-objects across an intestinal epithelial barrier: P-247. (2011) (2)
Shigella dysenteriae I enterotoxin: A unique myoelectric response of the small intestine (1978) (1)
Erratum: Serum regulates Na+/H+ exchange in Caco-2 cells by a mechanism which is dependent on F-actin (Journal of Biological Chemistry (1992) 267 (956-962)) (1993) (1)
Enterotoxigenic Escherichia coli-blood group A interactions intensify diarrheal severity. (2019) (1)
Serotonin (5HT)-induced active ileal secretion: Evidence of calcium dependence (1979) (1)
Food-borne and water-borne infections and the gastroenterologist. (1999) (1)
Case 35-1988: A 63-Year-Old Asplenic Man with Myelofibrosis, Fever, and Bloody Diarrhea (1988) (1)
Immunolocalization of ammonium ion transporters in gill mitochondria-rich cells of the terrestrial mudskipper fish, Periophthalmodon schlosseri (1999) (1)
Structure-function studies of membrane domain-cytoplasmic domain and membrane domain-membrane doman chimeras of Na+/H+ exchanger isoforms NHE1 and NHE3 (1998) (1)
Propranolol inhibition of cholera toxin induced intestinal secretion in the rat (1977) (1)
749 LPA/LPA5 Receptor Stimulation of NHE3 Involves Two Separate Events: Stimulation of NHE3 Exocytosis via EGFR and ERK and Dynamic Dissociation of NHE3 From the Microvillar (MV) Cytoskeleton/NHERF2 via PLC and a Novel PKC (2012) (1)
Practical Advice From a Basic and Translational Researcher at a Major Medical School (2016) (1)
Mechanical Stimuli Affect E. Coli Heat Stable Enterotoxin (ST)-Cyclic GMP Signaling in a Human Enteroid Intestine-Chip Diarrhea Model (2019) (1)
Measurements of Paracellular Water Flow in the Intestinal Epithelial CACO-2 and T84 Cells in Isotonic Conditions and Upon a Treatment With Anti-Constipation Drug Lubiprostone (2011) (1)
Na(+)/H(+) exchangers (NHE1-3) have similar turnover numbers but different percentages on the cell surface. (1999) (1)
Ca/sup + +/- and cyclic AMP-induced changes in intact cell phosphorylation of ileal microvillus membrane proteins (1986) (1)
744 Phospholipase Cγ (PLCγ) Directly Binds to the Na+/H+ Exchanger 3 (NHE3) C-Terminus Which Is Necessary for Basal and Calcium-Mediated Inhibition of NHE3 Activity (2008) (1)
G Protein-Coupled Receptors in Gastrointestinal Physiology III. Asymmetry in plasma membrane signal transduction: lessons from brush-border Na1/H1 exchangers* (1998) (1)
Effect of spironolactone on mineralo and glucocorticoid — induced increases in colonic NA and water absorption and Na-K-ATPase activity (1978) (1)
The Glycosphingolipid Gb3 in Metastatic Transformation of Colon Cancer (2005) (1)
Expression and regulation of a fusion protein of naih exchanger NHE3 and green fluorescent protein in epithelial Caco-2 cells (2000) (1)
Thomas Russell Hendrix, MD, October 17, 1920 – December 23, 2013 (2014) (1)
190 Human Small Intestinal Enteroids Enable Mechanistic Studies of cAMPInduced Changes in Intracellular pH (2014) (1)
A NHE3-related pseudogene is on human Chromosome 10; the functional gene maps to 5pl5.3 (1996) (1)
Cyclic AMP and Ca2+/calmodulin dependent protein phosphorylation in rat lacrimal gland basolateral membranes (1984) (1)
728 Zinc Stimulates Intestinal Na/H Exchanger 3 (NHE3) via Trafficking Effects in a Phospholipase C (PLC) Dependent Manner (2013) (0)
In Vitro Modeling of Human Enterohepatic Circulation Using Stem Cell-Derived Ileal Enteroids and Primary Cultures of Hepatocytes (2017) (0)
Proteome of murine jejunal brush border membrane vesicles (Journal of Proteome Research (2007) 6, 10, (4068-4079)) (2008) (0)
Cholinergic influence upon acid-stimulated serotonin release from duodenum (1981) (0)
Shiga toxin 1 transcellular transcytosis across T 84 intestinal epithelial cells (2008) (0)
269 - A Novel Model of Human Enteroids in the Intestine-Chip (I-C) Platform that Includes Dynamic Flow and Cyclic Strain for Physiological and Phamacological Studies of Intestinal Ion Transport (2018) (0)
Has a physiologic function for NHE2 finally been identified? (2022) (0)
Issue Information (2001) (0)
New drug treatment for diarrhoea. (1990) (0)
The cGMP-dependent kinase 2 is recruited to and colocalizes with Na+/H+ regulatory factor 2 and Na+/H+ exchanger isoform 3 during guanylate cycle C receptor activation in murine small intestinal brush border membrane in vivo (2014) (0)
34 – E.Coli Heat Stable Enterotoxin (ST) Inhibition of Nhe3 Occurs by Different Signaling Pathways Downstream of Cyclic Gmp in Murine Jejunum and Caco-2 Cells: A Warning About Assumed Equivalence (2019) (0)
537 NHERF2-NHERF3 Scaffolded Macrocomplex Is Necessary for E. coli Heat Stable Enterotoxin (STa)- Induced Intestinal Fluid Secretion (2016) (0)
Su1573 – Cholinergic-Induced Anion Secretion in Mouse Jejunal Enteroids is Regulated Through Synergy Between Intrinsic Enterocyte Muscarinic and Nicotinic Receptors (2019) (0)
Su1200 A Common NHE3 Non-Synonymous Polymorphism (C2405T/R799C) has Normal Transport Function and Similar Sensitivity to the Orally Active NHE3 Inhibitor, Tenapanor (2016) (0)
1015 A Novel Ser-Rich Motif in the NHE3 C-Terminal Regulatory Domain is Required for Stimulation of Na/H Exchange Activity by AKT as Well as for Direct Ezrin Binding to NHE3 (2010) (0)
23 - Human Colonoid Regeneration is Guided by Desert Hedgehog and WNT2B after Injury by Enterohemorrhagic E. Coli (EHEC) Secreted Serine Protease ESPP (2018) (0)
W1274 Macropinocytosis Is Involved in Shiga Toxin 1 Uptake and Transcytosis By Gb3-Negative Human Intestinal Epithelial Cells (2008) (0)
27 Neutral Na+ Absorption and Fluid/Anion Secretion Are Not Separated Processes in the Human Enteroid Model (2015) (0)
Su1199 Post-Transcriptional Regulation of Na-H Exchanger-3 (NHE3) by Aldosterone Involves microRNA-204 (2016) (0)
Mo1824 Asymmetric Brush Border Activation of Phospholipase D is Necessary for Carbachol Inhibition of NHE3 Activity (2012) (0)
977 Human Colonoids As a Model for Shiga Toxin Producing E. coli (STEC)-Induced Intestinal Epithelial Injury and Regeneration (2016) (0)
Development of an endogenous epithelial Na(+)/H(+) exchanger (NHE3) in three clones of caco-2 cells. (1999) (0)
1014 SRC Dynamically Associates With PLC-γ and is Necessary for CA2+-Mediated Inhibition of NHE3 Activity in CACO-2/BBE Cells (2010) (0)
Role of PDZ roteins NHERF and E3KARP in cyclic nucleotide regulation of NHE3 (2000) (0)
Air-Liquid-Interface Reorganizes Membrane Lipid and Enhance Recruitment of Slc26a3 to Lipid-Rich Domains in Human Colon (2022) (0)
Chronic exposure of ErbB TKIs inhibits DRA expression and activity through an ERK/Elk-1/CREB/AP-1 dependent pathway (2020) (0)
NHERF1 Knock out Mice Have Abnormal Tight Junctions and Increased Severity of B. Fragilis Enterotoxin Related Colitis Associated With Reduced Expression of Claudins 2 and 4 (2011) (0)
886 Do Mutations of NHE3 At the Site of Poorly Functioning NHE3 Polymorphisms Contribute to Diarrhea of Congenital Na Diarrhea (2009) (0)
Regulation of the epithelial brush border Na/H exchanger NHE3, a story of cytoskeleton and signaling complexes (2010) (0)
Faculty Opinions recommendation of Crystal structure of CHP2 complexed with NHE1-cytosolic region and an implication for pH regulation. (2006) (0)
Tu1268 THE INFLAMMATORY SIGNATURE OF HUMAN ENTEROIDS DERIVED FROM ULCERATIVE COLITIS PATIENTS IS MAINTAINED DURING LONGTERM PASSAGE (2020) (0)
T1853 NHERF1 and NHERF2 Separately Contribute to Basal and Acutely Regulated NHE3 Activity. An Exception is cAMP Inhibiton Which Can Be Mediated Either by NHERF1 or NHERF2 (2010) (0)
Farnesoid X receptor activation inhibits colonic epithelial CFTR expression ‐ a new target for antidiarrheal therapy? (2013) (0)
NHE3 contains a cleavable signal peptide followed by 11 membrane spanning domains: New insights into topology (2000) (0)
Evidence of an essential role of NHERF1 and NHEF2 in G‐protein coupled receptor regulation of CFTR‐mediated intestinal anion secretion in vivo (2009) (0)
Glucocorticoid-Mediated Increase in NHE3 Synthesis, Membrane Trafficking and Function is Differentially Impaired in NHERF2 Ko and NHERF3 (PDZK1) Ko Ileum (2011) (0)
Adipokine C1q/Tumor Necrosis Factor- Related Protein 3 (CTRP3) Attenuates Intestinal Inflammation Via Sirtuin 1/NF-κB Signaling (2022) (0)
The NHE3 interacting PDZ protein NHERF2 determines the lipid raft association of the apical Na+/H+ exchanger NHE3 in murine small intestine (2012) (0)
189 Basal and Stimulated BB NHE3 Activity Requires Intracellular SNX27, a PDZDomain Containing Binding Partner of NHE3 That Regulates Endosome to Plasma Membrane Trafficking (2014) (0)
Contents, Vol. 4, 1994 (1994) (0)
Ileal secretion causes choleresis in the rabbit: A new contributor to diarrhea? (1978) (0)
Secretagogues of Entamoeba histolytica: role in diarrhoea. (1988) (0)
Protein kinase C (PKC) is involved in translocation of endogenous apical NA/H exchanger (NHE3) in human colonic adenocarcinoma cells CACO-2 (1997) (0)
Presidential address. (2007) (0)
T1871 NHE3 Activity is Dependent on Direct Phosphatidylinositide Binding at Its Proximal Cytosolic Region (2010) (0)
256 Myosin VI is Responsible for Movement of NHE3 From the Microvillus of Polarized Caco-2-bbe Cells to the Intervillus Clefts Under Basal Conditions and With Ca2+ Stimulated Endocytosis (2010) (0)
Altered myoelectric activity of the small intestine in response to live Shigella dysenteriae: A toxin-mediated response (1978) (0)
A Novel GPCR in the Renal Proximal Tubules, Gprc5c, Is Involved in Systemic pH Regulation (2016) (0)
Measurement of cytosol free calcium in single intestinal epithelial cells a study using a fluorescence microscopy imaging system (1987) (0)
T1867 Proteome of the Small Intestinal Brush Border of the NHERF2 Knock out (Ko) Mouse: Changes in Transporters and Signaling Molecules (2010) (0)
Mo1766 Mucus Produced by Stem Cell Derived Human Colonoids Is an Early Target in Enterohemorrhagic E. coli Infection (2015) (0)
521 - Morphologic and Intestinal Stem Cell Gene Expression Changes in Crispr-Edited APC KO Human Colonoids (2018) (0)
Effect of dantrolene on active rabbit ileal electrolyte transport. Evidence for role of intracellular calcium stores in basal transport (1982) (0)
Increased Tear Secretion in a Patient with Pancreatic Cholera (1987) (0)
Constitutively active phosphatidlyinositol 3-kinase (Pl 3-K) and Akt are sufficient to stimulate NHE3: Insights in mechanisms of NHE3 stimulation (2001) (0)
592 HUMAN INTESTINAL STEM CELL (ISC)-DERIVED ENTEROIDS/COLONOIDS (HIE/HIC) FROM IBD PATIENTS DIFFERENTIALLY RESPOND TO CYTOKINES COMPARED TO ENTEROIDS FROM HEALTHY DONORS (2020) (0)
713 - A New Intestine-Chip Model to Study Human Intestinal Physiology and Pathophysiology (2018) (0)
Su1039 – Human Differentiated Enteroid Monolayers Exhibit Egfr/Mek- and Nf-Kb-Dependent Plasticity in a Model of Intestinal Trauma (2019) (0)
Presentation of the AGA Distinguished Achievement Award in Basic Science to Kim E. Barrett, PhD, AGAF. (2021) (0)
756 - Enterohemorrhagic E. Coli (EHEC) Secreted Serine Protease Espp, Stimulates Active Electrogenic Ion Transport in Human Colonoid Monolayers (2018) (0)
The Na+/H+ exchanger NHE1 and the lactate-H+ cotransporter MCT1 are spatially organized in C6 gliomas in rat brain. (2010) (0)
T1727 Myosin Vi Is Necessary for Setting Brush Border NHE3 Activity: An Effect On NHE3 Trafficking/Endocytosis (2009) (0)
The NHERF2 Dependent Dynamic Ca2+/LPA Regulation of NHE3 Mobility and Interaction At the Epithelial Brush Border (2010) (0)
SLC26A3 (DRA) is stimulated in a synergistic, intracellular Ca2+ dependent manner by cAMP AND ATP in intestinal epithelial cells (2022) (0)
Sa1084 MUSCARINIC AND NICOTINIC SIGNALING SYNERGISTICALLY REGULATE CHOLINERGIC-INDUCED ANION SECRETION THAT INVOLVES BOTH CACC AND CFTR IN THE MOUSE JEJUNAL ENTEROIDS (2020) (0)
Cholera Toxin Destabilizes Retromer to Inhibit NA+/H+ Exchanger3 Activity in Intestinal Epithelial Cells- Possible Therapeutic Role of a Retromer Stabilizer in Treating Diarrhea (2017) (0)
cGMP-dependent kinase 2, Na+/H+ regulatory factor 2, and Na+/H+ exchanger isoform 3 assemble within lipid rafts in murine small intestinal brush border membrane (2013) (0)
W1661 Reduced Stimulation of NHE3 Activity and Reduced Exocytosis with Knockdown of Clc-5, An Endosomal Chloride Channel (2009) (0)
D-Glucose Acts via SGLTI to Increase NHE 3 in Mouse Jejunal Brush Border by a NHERF 2-Dependent Process (2011) (0)
31 – Endosomal Snx17 Sets the Plasma Membrane Amount of Nhe3 and Prevents Its Degradation by Binding to the Nhe3 Cterminus (2019) (0)
Su1203 The Plasticity of the Intestinal Stem Cell Compartment and Its Induction Following Rotavirus Infection (2016) (0)
The lateral mobility of NHE3 on the apical membrane of polarized epithelial cells is limited by binding to PDZ domain proteins NHERF1/2 as determined by fluorescence recovery after photobleaching (FRAP) (2003) (0)
Table of Contents (1991) (0)
Sa1413 Enterohemorrhagic E. coli (EHEC)-Secreted Serine Protease EspP is an Enterotoxin and Stimulates Anion Secretion in Human Stem Cell Derived Colonoid Monolayers (2016) (0)
34 Human Intestinal Epithelial Response to Gastrointestinal Virus Infection Using Enteroids (2015) (0)
Do Diverse Mechanisms of Pathogenesis Lead to Final Common Pathways ? (2012) (0)
T1841 Differential Effect of NHE3 Kinase a Regulatory Protein (E3karp/NHERF2) Knockout on cAMP-, cGMP-, or [Ca2+]-Induced Inhibition of Na+/H+ Exchanger 3 (NHE3) Activity Along the Murine Intestinal Tract (2010) (0)
Mo1790 The NHE3 C-Terminal Stimulatory Complex Acts by Changes in Its Phosphorylation and Dynamic Association With Direct Ezrin Binding (2013) (0)
Interaction between Ca/sup + +/-channel antagonists and. cap alpha. /sub 2/-adrenergic receptors in rabbit ileal cell membrane (1986) (0)
Mo1751 CGMP-Dependent Kinase 2, Na+/H+ Regulatory Factor 2, and Na+/H+ Exchanger Isoform 3 Dynamically Assemble Within Lipid Rafts in Murine Small Intestinal Brush Border Membrane (2014) (0)
Chloroquine diphosphate reverses cholera toxin-induced ileal secretion in the rat (1980) (0)
Ileal and Colonic Enteroids as a Model for Studying FXR Regulation of the Enterohepatic Circulation in Humans (2020) (0)
CK2 Phosphorylation of NHE3-S 719 Regulates NHE3 Activity by Organizing the C-Terminus to form Multiple Signaling Complexes and Establish Lipid Raft Distribution (2017) (0)
Tu1577: SORTING NEXIN-27 REGULATES THE ROUTE OF APICAL MEMBRANE TRAFFICKING OF DRA BY PREVENTING RETROGRADE TRAFFICKING IN INTETNAL EPITHELIAL CELLS (2022) (0)
430 - Epithelial-Secreted WNT Ligands are Essential Drivers of Intestinal Stem Cell Response to Virus-Induced Villus Damage (2018) (0)
551 Shiga Toxin 1 Uptake By Intestinal Epithelial Cells Is CDC-42 Mediated and Clathrin-Independent (2009) (0)
Fr149 CHOLERA TOXIN DISRUPTS CELL CYCLE HOMEOSTASIS IN CRYPT-LIKE HUMAN ENTEROIDS (2021) (0)
Faculty Opinions recommendation of Mechanism of IFN-gamma-induced endocytosis of tight junction proteins: myosin II-dependent vacuolarization of the apical plasma membrane. (2005) (0)
Erratum: Enterotoxigenic Escherichia coli-blood group a interactions intensify diarrheal severity (Journal of Clinical Investigation (2018)128(8)(3298-3311)Doi:10.1172/JCI97659) (2018) (0)
Deficits in Enterocyte Apical Transporters Associated with Loss of Myosin VB (2017) (0)
Renal Role of Gprc5c in Regulating Systemic pH Homeostasis (2017) (0)
Adipokine C1q/Tumor necrosis factor-Related Protein 3 (CTRP3) Attenuates Intestinal Inflammation via Histone Deacetylase Sirtuin 1 (SIRT1)/NF-κB Signaling (2022) (0)
Mo1816 The NHE3 Interacting PDZ Protein NHERF2 is Strongly Lipid Raft-Associated and Determines the Raft Association of the Apical Na+/H+ Exchanger NHE3 in Murine Small Intestinal Brush Border Membrane (2012) (0)
S1759 NHE3 and NHERF2 Bind Dynamically At the Epithelial Brush Border in Response to Elevated Ca2+, Revealed By FRET (2009) (0)
Cloning and Expression of a Rabbit cDNA Encoding a Serum-activated (1993) (0)
Separate functions for brush border membrane and endosomal NHE3 in a polarized epithelial cell line (2000) (0)
New melanocortin-like peptide of E. coli can suppress inflammation via the mammalian melanocortin-1 receptor (MC1R): possible endocrine-like function for microbes of the gut (2017) (0)
mOrange2, a Genetically Encoded, pH Sensitive Fluorescent Protein, is an Alternative to BCECF-AM to Measure Intracellular pH to Determine NHE3 and DRA Activity. (2022) (0)
Basic Fibroblast Growth Factor Stimulates Surface Expression and Activity of Na 1 / H 1 Exchanger NHE 3 via Mechanism Involving Phosphatidylinositol 3-Kinase * (2000) (0)
Na+/H+ exchanger NHE3 interacts with PDZ domains of the regulatory proteins, E3KARP and NHERF (1998) (0)
Ileal secretion of water and electrolytes induced by acute elevation of intraluminal hydrostatic pressure (1978) (0)
Evidence for a Nhe3 Related Pseudogene on Human Chromosome-10 (1995) (0)
CAM Kinase IIγ Inhibits Activity and Directly Binds the C-Terminal Domain of the Intestinal Brush Border Na/H Exchanger NHE3 in a Dymanic, Ca2+ Dependent Manner (2011) (0)
Enterohemorrhagic E. coli (EHEC) Secreted Serine Protease EspP‐Induced Injury and Regeneration is Guided by Desert Hedgehog and WNT2B in Human Colonoids (2020) (0)
Faculty Opinions recommendation of Impaired gastric acid secretion in mice with a targeted disruption of the NHE4 Na+/H+ exchanger. (2005) (0)
Mo1654 Decreased Intestinal NHE3 Expression by mTOR Inhibition and Its Implication in Rapamycin Related Diarrhea in Renal Transplant Recipients (2012) (0)
35 - Anion Secretion is Quantitatively Rather than Qualitatively Different Between Crypt-Like Undifferentiated and Villuslike Differentiated Human Duodenal Enteroid Monolayers (2018) (0)
Differences in plasma membrane half-life and membrane trafficking of the epithelial Na+/H+exchangers NHE2 and NHE3: Insights into functions of these proteins (2000) (0)
Mo1945 Human Intestinal Enteroids As a Model System for the Study of Enteric Virus Pathogenesis (2014) (0)
Subject Index, Vol. 4, 1994 (1994) (0)
Fr584 MUSCARINIC AND NICOTINIC PATHWAYS SYNERGISTICALLY REGULATE CHOLINERGIC-INDUCED ANION SECRETION BY NICOTINIC-INDUCED CROSS-OVER OF CA2+ AND CAMP SIGNALING IN MOUSE JEJUNAL ENTEROIDS (2021) (0)
584 DYNAMIC INTERACTIONS AMONG CFTR, NHERF4 (NF4) AND DRA (SLC26A3) ARE RESPONSIBLE FOR CHOLERA TOXIN/FORSKOLIN (CTX/FSK) STIMULATION OF DRA ACTIVITY AND INVOLVE PROTEIN TRAFFICKING AND CFTR-DRA INTERACTIONS (2020) (0)
Human duodenal bicarbonate absorption involves both brush border NA+/H+ exchangers NHE2 and NHE3 (2000) (0)
Shigella enterotoxin stimulated intestinal secretion is not mediated by cyclic adenosine monophosphate (cAMP) (1974) (0)
AGA InstitutePresidential Address (2007) (0)
822: CALCIUM-SENSING RECEPTOR ACTIVATOR CINACALCET REDUCES CHLORIDE AND FLUID SECRETION IN MOUSE AND HUMAN INTESTINAL ORGANOID MODELS OF SECRETORY DIARRHEA (2022) (0)
Lysophosphatidic acid stimulates the brush border Na/H exchanger NHE3 in Na absorptive epithelial cells by increasing exocytic trafficking by a PI 3-kinase dependent mechanism that requires E3KARP (2003) (0)
Human enteroids: preclinical models of non-inflammatory diarrhea (2013) (0)
NHE2 is the major brush border NA/H exchanger isoform in the avian colon and is stimulated by mineralocorticoids (1997) (0)
Mo1756 Phospholipase D Isoforms 1 and 2 Are Required for Carbachol Inhibition of NHE3 in CaCO-2/BBe Cells (2014) (0)
Mo1793 CK2 Phosphorylatoin of NHE3 At S719 Is Necessary for the PI3-K/AKT Component of Basal NHE3 Activity and for Carbachol/Ca2+ but Not cAMP Inhibition-Effects Involving the Lipid Raft Pool of NHE3 (2013) (0)
SRC Dynamic Increase in Direct Binding to the PLC-γ SH2 Domain(S), but Not NHE3, is Necessary to Form Signaling Complexes to Allow Carbachol Mediated Inhibition of NHE3 Activity in CACO-2/Bbe Cells (2011) (0)
Ca sup 2+ channel blockers interact with. alpha. sub 2 -adrenergic receptors in rabbit ileum (1988) (0)
NA+/H+-exchanger 3 (NHE3) is present in lipid rafts in the ileal absorptive cell brush border: A role for rafts and the actin cytoskeleton in endocytosis of NHE3 (2000) (0)
The clinicopathologic spectrum of ischemic colitis: Prognostic implications of an evidence-based comprehensive classification (2000) (0)
788 - Cholera Toxin (CTX)/Forskolin (FSK) Stimulate Dra (SLC26A3) Related HCO3 Secretion which Involves Apical Trafficking of Dra in Ileal and Proximal Colonic Enteroid Monolayers and CACO-2 Cells (2018) (0)
Intact jejunal absorption of a synthetic nonapeptide renin inhibitor (1984) (0)
Mo1121: ADIPOKINE C1Q/TNF-RELATED PROTEIN 3 (CTRP3) SUPPRESSES COLONIC INFLAMMATION IN MOUSE COLITIS MODELS (2022) (0)
Erratum: (Journal of Physiology (2005) (5-6)) (2005) (0)
Protein-protein interactions and signalling complexes in regulation of the brush border Na/H antiporter, NHE3 (2014) (0)
ADF/COF Have Different Effects on Intestinal Brush Border Structure and NHE3 Activity (2015) (0)
Effects of calcium antagonist 3 4 5 trimethoxybenzoate 8 n n diethylaminooctyl ester on active sodium and chloride transport in rabbit ileum (1986) (0)
EGF stimulation of ileal naCl absorption requires SRC family kinase activation of brush border (BB) PI 3-kinase (1998) (0)
Sa1089 SLC26A3 (DRA) IS STIMULATED BY BOTH CAMP AND CA2+ SIGNALING AND THE EFFECT IS SYNERGISTIC IN INTESTINAL EPITHELIAL CELLS BY A PROCESS THAT REQUIRES IRBIT. (2020) (0)
Faculty Opinions recommendation of Shank2 associates with and regulates Na+/H+ exchanger 3. (2006) (0)
NHE3 Contains Two Cytoskeleton Associated C-Terminal, Ezrin Containing Signaling Complexes, One for Acute Stimulation and One for Inhibition, Which Together Account for Acute NHE3 Regulation (2011) (0)
The Zinc Transporter ZIP8 is Induced by Inflammatory Stimuli on the Apical Membrane of Intestinal Epithelial Cells: Potential Role in Interactions with the Microbiota in Crohn's Disease (2017) (0)
Carbachol-mediated inhibition of Na/H exchanger 3 (NHE3) in ileal brush border (BB) occurs through regulated trafficking and complex formation and involves multiple pools of NHE3 (2003) (0)
Author response: Duodenum Intestine-Chip for preclinical drug assessment in a human relevant model (2019) (0)
882 D-Glucose/SGLT1 Stimulates NHE3 Activity in Intact Mouse Jejunum, a Contributor to the Effect of Ors, By An AKT Dependent Process (2009) (0)
Regulation of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) by the Nuclear Bile Acid Receptor, Farnesoid X Receptor (2022) (0)
Epithelial Biology and Secretion Both NHERF3 and NHERF2 are necessary for multiple aspects of acute regulation of NHE3 by elevated Ca 2 (cid:2) , cGMP, and lysophosphatidic acid (2018) (0)
Epithelial WNT Ligands Ar e Essential Drivers of Intestinal Stem Cell Activation Graphical (2018) (0)
Oral Sessions (2014) (0)
Actin turnover is linked to Shiga toxin 1 transcellular transcytosis across intestinal epithelial cells (2007) (0)
Regulation of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) by the Nuclear Bile Acid Receptor, Farnesoid X Receptor (2020) (0)
Royal Academy of Medicine in Ireland section of surgery (1994) (0)
Mo1747 NHERF2/NHERF3 Hetero-Dimerization Is Required for Carbachol Inhibition of NHE3 Activity That Involves Formation of NHE3 Macro-Complexes (2014) (0)
The utility of endoscopy in the management of acute ischemic colitis (2001) (0)
1129: MORANGE2, A GENETICALLY ENCODED, PH SENSITIVE FLUORESCENT PROTEIN, IS AN ALTERNATIVE TO BCECF-AM TO MEASURE INTRACELLULAR PH TO DETERMNE NHE3 AND DRA ACTIVITY (2022) (0)
Rotavirus Infection Induces LGR5 Intestinal Stem Cell Population via WNT Pathway Stimulation (2017) (0)
Faculty Opinions recommendation of Epithelial myosin light chain kinase-dependent barrier dysfunction mediates T cell activation-induced diarrhea in vivo. (2005) (0)
Significance ofAbnormal Rabbit Ileal Histology inthe Pathogenesis ofDiarrhea (1979) (0)
Calcium/Calmodulin Dependent Protein Kinase II Constitutively Binds, Phosphorylates, and Regulates the Ileal BB Na+/H+ Exchanger NHE3 ; NHE3 IS A NOVEL MEMBER OF THE CaM KINASE II BINDING PROTEINS (2006) (0)
521 LONG-LASTING INFLAMMATION IN PATIENTS WITH ULCERATIVE COLITIS CAUSES PERMANENT CHANGES IN GOBLET CELL FUNCTION (2021) (0)
Effect of spironolactone (S) on mineralocorticoid and glucocorticoid-induced increases in colonic NA and water absorption (1977) (0)
401 Human Ex Vivo Enteroid Culture As a Functional Model of Human Small Intestinal Physiology and Pathophysiology: Inhibition of Na+ Absorption by cAMP and Rotavirus and Stimulation of Cl− Secretion by cAMP (2013) (0)
Fr143 SLC26A3 (DRA) STIMULATES CAMP MEDIATED FLUID SECRETION IN F508DEL-CFTR ORGANOIDS: AN EFFECT ON CFTR AND DRA EXPRESSING ENTEROCYTES. (2021) (0)
Issue Information (2001) (0)
Issue Information (2001) (0)
Mechanisms of Intestinal Electrolyte Transport and Regulation by Calcium (1984) (0)
From meetings (1988) (0)
Su1012 – Mechanical Stimuli Affect Enterotoxigenic E. Coli (ETEC) Heat Stable Enterotoxin (ST)-Cyclic Nucleotide Signaling by Altering Mrp4 Expression in a Human Enteroid Monolayer Model of Etec Diarrhea (2019) (0)
Immunolocalization of ion transport proteins in the gills of teleost fishes (1999) (0)
M1723 Basal Activity of the Epithelial Brush Border Na/H Exchanger NHE3 Is Stimulated By Both PI-3K and AKT-Dependent and Independent Pathways (2008) (0)
Cyclic GMP-dependent protein kinase regulation of epithelial transporters (2003) (0)
Su1844 NHERF2 Contains a Phosphorylatable Ezrin Binding Regulatory Domain, a Newly Identified Motif (2015) (0)
Actin depolymerizing factor but not cofilin‐1 is necessary to have a normal intestinal brush border (1109.16) (2014) (0)
Refractory Lymphocytic Enterocolitis and Tumor Necrosis Factor Antagonist Therapy: 258 (2008) (0)
Prevention and reversal of cholera toxin induced intestinal secretion by methyl prednisolone (MP) (1976) (0)
Tu1401 Differential Intracellular Calcium Inhibition of NHE3 Activity (2015) (0)

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