Mark Donowitz
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Engineering Computer Science
Mark Donowitz's Degrees
- PhD Computer Science Stanford University
- Masters Electrical Engineering University of California, Berkeley
- Bachelors Computer Engineering University of California, Berkeley
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(Suggest an Edit or Addition)Mark Donowitz's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The burden of selected digestive diseases in the United States. (2002) (1462)
- TAZ: a novel transcriptional co‐activator regulated by interactions with 14‐3‐3 and PDZ domain proteins (2000) (680)
- The protein kinase Akt induces epithelial mesenchymal transition and promotes enhanced motility and invasiveness of squamous cell carcinoma lines. (2003) (648)
- Evolutionary origins of eukaryotic sodium/proton exchangers. (2005) (512)
- cAMP-mediated inhibition of the epithelial brush border Na+/H+ exchanger, NHE3, requires an associated regulatory protein. (1997) (446)
- Molecular physiology of intestinal Na+/H+ exchange. (2005) (362)
- Cloning and sequencing of a rabbit cDNA encoding an intestinal and kidney-specific Na+/H+ exchanger isoform (NHE-3). (1992) (322)
- Na+/H+ exchanger regulatory factor 2 directs parathyroid hormone 1 receptor signalling (2002) (315)
- NHE2 and NHE3 are human and rabbit intestinal brush-border proteins. (1996) (304)
- Differential roles of NHERF1, NHERF2, and PDZK1 in regulating CFTR-mediated intestinal anion secretion in mice. (2009) (297)
- Human Intestinal Enteroids: a New Model To Study Human Rotavirus Infection, Host Restriction, and Pathophysiology (2015) (265)
- A primary human macrophage-enteroid co-culture model to investigate mucosal gut physiology and host-pathogen interactions (2017) (257)
- NaCl uptake by the branchial epithelium in freshwater teleost fish: an immunological approach to ion-transport protein localization. (2000) (254)
- Akt as a mediator of cell death (2003) (246)
- Kinetics and regulation of three cloned mammalian Na+/H+ exchangers stably expressed in a fibroblast cell line. (1993) (245)
- SLC9/NHE gene family, a plasma membrane and organellar family of Na⁺/H⁺ exchangers. (2013) (217)
- Mammalian Na+/H+ exchanger gene family: structure and function studies. (1995) (216)
- Cloning and expression of a rabbit cDNA encoding a serum-activated ethylisopropylamiloride-resistant epithelial Na+/H+ exchanger isoform (NHE-2). (1993) (201)
- Human Enteroids/Colonoids and Intestinal Organoids Functionally Recapitulate Normal Intestinal Physiology and Pathophysiology* (2015) (198)
- NHERF family and NHE3 regulation (2005) (197)
- Regulatory binding partners and complexes of NHE3. (2007) (196)
- Functional Coupling of Human Microphysiology Systems: Intestine, Liver, Kidney Proximal Tubule, Blood-Brain Barrier and Skeletal Muscle (2017) (183)
- The glycosphingolipid globotriaosylceramide in the metastatic transformation of colon cancer. (2005) (182)
- Free radicals and other reactive oxygen metabolites in inflammatory bowel disease: cause, consequence or epiphenomenon? (1992) (177)
- Enterohemorrhagic Escherichia coli Reduces Mucus and Intermicrovillar Bridges in Human Stem Cell-Derived Colonoids (2015) (176)
- Immunolocalization of ion-transport proteins to branchial epithelium mitochondria-rich cells in the mudskipper (Periophthalmodon schlosseri). (2000) (175)
- Polarized distribution of key membrane transport proteins in the rat submandibular gland (1996) (171)
- Squalamine inhibits angiogenesis and solid tumor growth in vivo and perturbs embryonic vasculature. (1998) (167)
- Human Na(+)/H(+) exchanger isoform 6 is found in recycling endosomes of cells, not in mitochondria. (2002) (164)
- Molecular cloning and expression of a cDNA encoding the rabbit ileal villus cell basolateral membrane Na+/H+ exchanger. (1991) (159)
- Cloning, tissue distribution, and functional analysis of the human Na+/N+ exchanger isoform, NHE3. (1995) (159)
- Arachidonic acid metabolites and their role in inflammatory bowel disease. An update requiring addition of a pathway. (1985) (151)
- Human enteroids as an ex-vivo model of host–pathogen interactions in the gastrointestinal tract (2014) (146)
- NHERF associations with sodium-hydrogen exchanger isoform 3 (NHE3) and ezrin are essential for cAMP-mediated phosphorylation and inhibition of NHE3. (2000) (146)
- The Concise Guide to Pharmacology 2013/14: Overview (2013) (143)
- Human Enteroids as a Model of Upper Small Intestinal Ion Transport Physiology and Pathophysiology. (2016) (142)
- Structure/function studies of mammalian Na‐H exchangers‐‐an update. (1995) (140)
- Differential renal distribution of NHERF isoforms and their colocalization with NHE3, ezrin, and ROMK. (2001) (138)
- Ca2+-dependent Inhibition of Na+/H+ Exchanger 3 (NHE3) Requires an NHE3-E3KARP-α-Actinin-4 Complex for Oligomerization and Endocytosis* (2002) (136)
- Secretory diarrhoea: mechanisms and emerging therapies (2015) (135)
- Functional characteristics of a cloned epithelial Na+/H+ exchanger (NHE3): resistance to amiloride and inhibition by protein kinase C. (1993) (132)
- Mutations in TTC37 cause trichohepatoenteric syndrome (phenotypic diarrhea of infancy). (2010) (131)
- Na+‐H+ exchanger 3 (NHE3) is present in lipid rafts in the rabbit ileal brush border: a role for rafts in trafficking and rapid stimulation of NHE3 (2001) (128)
- Separate C-terminal Domains of the Epithelial Specific Brush Border Na+/H+ Exchanger Isoform NHE3 Are Involved in Stimulation and Inhibition by Protein Kinases/Growth Factors (*) (1995) (128)
- Role of lipid rafts in Shiga toxin 1 interaction with the apical surface of Caco-2 cells. (2001) (124)
- Glucocorticoid stimulation of ileal Na+ absorptive cell brush border Na+/H+ exchange and association with an increase in message for NHE-3, an epithelial Na+/H+ exchanger isoform. (1993) (120)
- Ca2+ and cyclic AMP in regulation of intestinal Na, K, and Cl transport. (1986) (119)
- Brush Border Phosphatidylinositol 3-Kinase Mediates Epidermal Growth Factor Stimulation of Intestinal NaCl Absorption and Na/H Exchange (*) (1996) (112)
- Downregulation of sodium transporters and NHERF proteins in IBD patients and mouse colitis models: Potential contributors to IBD‐associated diarrhea (2009) (112)
- Glucagon secretion in acute and chronic pancreatitis. (1975) (111)
- Evaluation of patients with chronic diarrhea. (1995) (108)
- NHE3 regulatory complexes (2009) (103)
- Squalamine, a novel cationic steroid, specifically inhibits the brush-border Na+/H+exchanger isoform NHE3. (1999) (102)
- Reduced sodium/proton exchanger NHE3 activity causes congenital sodium diarrhea. (2015) (102)
- cGMP Inhibition of Na+/H+ Antiporter 3 (NHE3) Requires PDZ Domain Adapter NHERF2, a Broad Specificity Protein Kinase G-anchoring Protein* (2005) (100)
- Human mini-guts: new insights into intestinal physiology and host–pathogen interactions (2016) (100)
- Lysophosphatidic acid stimulates the intestinal brush border Na(+)/H(+) exchanger 3 and fluid absorption via LPA(5) and NHERF2. (2010) (99)
- A paradox of transcriptional and functional innate interferon responses of human intestinal enteroids to enteric virus infection (2017) (98)
- Calcium dependence of serotonin-induced changes in rabbit ileal electrolyte transport. (1980) (97)
- Duodenum Intestine-Chip for preclinical drug assessment in a human relevant model (2020) (97)
- Ca2+-dependent inhibition of NHE3 requires PKC alpha which binds to E3KARP to decrease surface NHE3 containing plasma membrane complexes. (2003) (94)
- Macropinocytosis in Shiga toxin 1 uptake by human intestinal epithelial cells and transcellular transcytosis. (2009) (92)
- Corrigendum: Functional Coupling of Human Microphysiology Systems: Intestine, Liver, Kidney Proximal Tubule, Blood-Brain Barrier and Skeletal Muscle (2017) (92)
- Pharmacological Properties of N-(3,5-Diamino-6-chloropyrazine-2-carbonyl)-N′-4-[4-(2,3-dihydroxypropoxy)phenyl]butyl-guanidine Methanesulfonate (552-02), a Novel Epithelial Sodium Channel Blocker with Potential Clinical Efficacy for Cystic Fibrosis Lung Disease (2008) (88)
- Effect of serotonin treatment on intestinal transport in the rabbit. (1977) (88)
- Ca2+ in the control of active intestinal Na and Cl transport: involvement in neurohumoral action. (1983) (87)
- D-glucose acts via sodium/glucose cotransporter 1 to increase NHE3 in mouse jejunal brush border by a Na+/H+ exchange regulatory factor 2-dependent process. (2011) (87)
- Lysophosphatidic Acid Stimulates Brush Border Na+/H+ Exchanger 3 (NHE3) Activity by Increasing Its Exocytosis by an NHE3 Kinase A Regulatory Protein-dependent Mechanism* (2003) (86)
- Na+/H+ Exchanger NHE3 Activity and Trafficking Are Lipid Raft-dependent* (2006) (85)
- Genome-Wide Analysis Reveals the Vacuolar pH-Stat of Saccharomyces cerevisiae (2011) (84)
- Quantitative contribution of NHE2 and NHE3 to rabbit ileal brush-border Na+/H+ exchange. (1998) (81)
- Na+/H+ exchanger-2 is an O-linked but not an N-linked sialoglycoprotein. (1994) (80)
- Transepithelial resistance can be regulated by the intestinal brush-border Na(+)/H(+) exchanger NHE3. (2000) (80)
- The roles of PDZ-containing proteins in PLC-β-mediated signaling (2001) (77)
- Effect of dioctyl sodium sulfosuccinate on colonic fluid and electrolyte movement. (1975) (75)
- CFTR protein expression in primary and cultured epithelia. (1992) (75)
- Genistein and tyrphostin 47 stimulate CFTR-mediated Cl- secretion in T84 cell monolayers. (1995) (74)
- Basic Fibroblast Growth Factor Stimulates Surface Expression and Activity of Na+/H+ Exchanger NHE3 via Mechanism Involving Phosphatidylinositol 3-Kinase* (2000) (74)
- Regulation of Tight Junction Resistance in T84 Monolayers by Elevation in Intracellular Ca2+: A Protein Kinase C Effect (1996) (73)
- Effect of serotonin on active electrolyte transport in rabbit ileum, gallbladder, and colon. (1980) (73)
- The Na+/H+ exchange isoform NHE3 regulates basal canine ileal Na+ absorption in vivo. (1997) (73)
- Membrane‐limited expression and regulation of Na+‐H+ exchanger isoforms by P2 receptors in the rat submandibular gland duct (1998) (72)
- Tissue-specific Regulation of Sodium/Proton Exchanger Isoform 3 Activity in Na+/H+ Exchanger Regulatory Factor 1 (NHERF1) Null Mice (2007) (71)
- Inhibition of sodium/hydrogen exchanger 3 in the gastrointestinal tract by tenapanor reduces paracellular phosphate permeability (2018) (71)
- The NHE3 Juxtamembrane Cytoplasmic Domain Directly Binds Ezrin: Dual Role In NHE3 Trafficking and Movement In the Brush Border (2006) (70)
- The lateral mobility of NHE3 on the apical membrane of renal epithelial OK cells is limited by the PDZ domain proteins NHERF1/2, but is dependent on an intact actin cytoskeleton as determined by FRAP (2004) (70)
- Defective jejunal and colonic salt absorption and alteredNa+/H+ exchanger 3 (NHE3) activity in NHE regulatory factor 1 (NHERF1) adaptor protein-deficient mice (2009) (69)
- Regulation of the Epithelial Brush Border Na+/H+ Exchanger Isoform 3 Stably Expressed in Fibroblasts by Fibroblast Growth Factor and Phorbol Esters Is Not through Changes in Phosphorylation of the Exchanger* (1997) (68)
- Entamoeba histolytica causes intestinal secretion: role of serotonin. (1983) (68)
- Prevention and reversal of cholera enterotoxin-induced intestinal secretion by methylprednisolone induction of Na+-K+-ATPase. (1976) (68)
- Akt2, phosphatidylinositol 3-kinase, and PTEN are in lipid rafts of intestinal cells: role in absorption and differentiation. (2004) (68)
- Carbachol regulation of rabbit ileal brush border Na+–H+ exchanger 3 (NHE3) occurs through changes in NHE3 trafficking and complex formation and is Src dependent (2004) (67)
- Farnesoid X receptor agonists attenuate colonic epithelial secretory function and prevent experimental diarrhoea in vivo (2013) (66)
- Na(+)/H(+) exchanger 3 is in large complexes in the center of the apical surface of proximal tubule-derived OK cells. (2002) (66)
- Hyperosmolarity inhibits the Na+/H+ exchanger isoforms NHE2 and NHE3: an effect opposite to that on NHE1. (1996) (64)
- Kinetics and regulation of a polarized Na(+)-H+ exchanger from Caco-2 cells, a human intestinal cell line. (1991) (63)
- A new look at laxative action. (1975) (62)
- Na+/H+ Exchanger Isoform 2 (NHE2) is Expressed in the Apical Membrane of the Medullary Thick Ascending Limb (1997) (61)
- Rabbit ileal villus cell brush border Na+/H+ exchange is regulated by Ca2+/calmodulin-dependent protein kinase II, a brush border membrane protein. (1990) (59)
- Elevated intracellular Ca2+ acts through protein kinase C to regulate rabbit ileal NaCl absorption. Evidence for sequential control by Ca2+/calmodulin and protein kinase C. (1989) (58)
- Dopamine stimulation of active Na and Cl absorption in rabbit ileum: interaction with alpha 2-adrenergic and specific dopamine receptors. (1982) (57)
- C-terminal domains of Na(+)/H(+) exchanger isoform 3 are involved in the basal and serum-stimulated membrane trafficking of the exchanger. (2000) (57)
- ClC-5: role in endocytosis in the proximal tubule. (2005) (56)
- Cystic Fibrosis Transmembrane Conductance Regulator Activation Is Reduced in the Small Intestine of Na+/H+ Exchanger 3 Regulatory Factor 1 (NHERF-1)- but Not NHERF-2-deficient Mice* (2007) (56)
- Casein kinase 2 binds to the C terminus of Na+/H+ exchanger 3 (NHE3) and stimulates NHE3 basal activity by phosphorylating a separate site in NHE3. (2008) (55)
- Constitutively Active Phosphatidylinositol 3-Kinase and AKT Are Sufficient to Stimulate the Epithelial Na+/H+ Exchanger 3* (2001) (55)
- Half-lives of plasma membrane Na(+)/H(+) exchangers NHE1-3: plasma membrane NHE2 has a rapid rate of degradation. (2001) (52)
- Immunolocalisation of sodium/proton exchanger-like proteins in the gills of elasmobranchs. (2002) (52)
- Colo-rectal biopsy in inflammatory bowel disease. (1977) (52)
- Structure/function studies of the epithelial isoforms of the mammalian Na+/H+ exchanger gene family (1993) (51)
- Short‐Term Regulation of NHE3 by EGF and Protein Kinase C but Not Protein Kinase A Involves Vesicle Trafficking in Epithelial Cells and Fibroblasts (2000) (50)
- The attrition of young physician-scientists: problems and potential solutions. (2007) (50)
- Na+/H+ exchangers (NHE1-3) have similar turnover numbers but different percentages on the cell surface. (1999) (48)
- Calcium dependence of basal electrolyte transport in rabbit ileum. (1982) (47)
- Effect of enterotoxins of Vibrio cholerae, Escherichia coli, and Shigella dysenteriae type 1 on fluid and electrolyte transport in the colon. (1976) (47)
- NHERF1 and NHERF2 are necessary for multiple but usually separate aspects of basal and acute regulation of NHE3 activity. (2011) (47)
- Serum regulates Na+/H+ exchange in Caco-2 cells by a mechanism which is dependent on F-actin. (1992) (46)
- Carbachol- and elevated Ca(2+)-induced translocation of functionally active protein kinase C to the brush border of rabbit ileal Na+ absorbing cells. (1991) (46)
- Epithelial WNT Ligands Are Essential Drivers of Intestinal Stem Cell Activation. (2018) (46)
- Human duodenal mucosal brush border Na(+)/H(+) exchangers NHE2 and NHE3 alter net bicarbonate movement. (2001) (46)
- Functional significance of intestinal Na+-K+-ATPase: in vivo ouabain inhibition. (1978) (44)
- Human enteroids: preclinical models of non-inflammatory diarrhea (2013) (44)
- A polarized salivary cell monolayer useful for studying transepithelial fluid movement in vitro (1998) (44)
- The Spatial Organization of Proton and Lactate Transport in a Rat Brain Tumor (2011) (43)
- Effects of phorbol esters on sodium and chloride transport in rat colon. (1986) (43)
- In birds, NHE2 is major brush-border Na+/H+ exchanger in colon and is increased by a low-NaCl diet. (1998) (41)
- Cyclic GMP Kinase II (cGKII) Inhibits NHE3 by Altering Its Trafficking and Phosphorylating NHE3 at Three Required Sites (2014) (41)
- Development of an endogenous epithelial Na+/H+exchanger (NHE3) in three clones of Caco-2 cells. (1999) (41)
- The Contributions of Human Mini-Intestines to the Study of Intestinal Physiology and Pathophysiology. (2017) (40)
- Pathogenesis of Shigella diarrhea. XVI. Selective targetting of Shiga toxin to villus cells of rabbit jejunum explains the effect of the toxin on intestinal electrolyte transport. (1989) (40)
- Leu143 in the putative fourth membrane spanning domain is critical for amiloride inhibition of an epithelial Na+/H+ exchanger isoform (NHE-2). (1993) (40)
- Na(+)/H(+) exchanger NHE3 has 11 membrane spanning domains and a cleaved signal peptide: topology analysis using in vitro transcription/translation. (2000) (40)
- Freeze-thaw and high-voltage discharge allow macromolecule uptake into ileal brush-border vesicles. (1987) (39)
- Hyperthermia effects on cytosolic [Ca2+]: analysis at the single cell level by digitized imaging microscopy and cell survival. (1991) (39)
- Challenges in IBD Research: Preclinical Human IBD Mechanisms. (2019) (38)
- Regulation of the rabbit ileal brush-border Na+/H+ exchanger by an ATP-requiring Ca++/calmodulin-mediated process. (1988) (38)
- Role of acid/base homeostasis in the suppression of apoptosis in haemopoietic cells by v-Abl protein tyrosine kinase. (1997) (38)
- NHERF2 is necessary for basal activity, second messenger inhibition, and LPA stimulation of NHE3 in mouse distal ileum. (2011) (38)
- Loss of PDZ‐adaptor protein NHERF2 affects membrane localization and cGMP‐ and [Ca2+]‐ but not cAMP‐dependent regulation of Na+/H+ exchanger 3 in murine intestine (2010) (37)
- Discovery and development of antisecretory drugs for treating diarrheal diseases. (2014) (37)
- Proteome of murine jejunal brush border membrane vesicles. (2007) (37)
- Effect of Shigella enterotoxin on electrolyte transport in rabbit ileum. (1975) (37)
- Effect of extracellular calcium depletion on epithelial structure and function in rabbit ileum: a model for selective crypt or villus epithelial cell damage and suggestion of secretion by villus epithelial cells. (1982) (37)
- Trifluoperazine reversal of secretory diarrhea in pancreatic cholera. (1980) (37)
- Neural control of acid-induced serotonin release from rabbit duodenum. (1983) (36)
- Enterotoxigenic Escherichia coli–blood group A interactions intensify diarrheal severity (2018) (36)
- Reversible sulfasalazine-induced granulomatous hepatitis. (1981) (36)
- Translating molecular physiology of intestinal transport into pharmacologic treatment of diarrhea: stimulation of Na+ absorption. (2014) (36)
- Molecular Properties, Kinetics and Regulation of Mammalian Na+/H+ Exchangers (1994) (36)
- The neurohumoral secretagogues carbachol, substance P and neurotensin increase Ca++ influx and calcium content in rabbit ileum. (1982) (36)
- THE EPITHELIAL BRUSH BORDER Na+/H+ EXCHANGER NHE3 ASSOCIATES WITH THE ACTIN CYTOSKELETON BY BINDING TO EZRIN DIRECTLY AND VIA PDZ DOMAIN‐CONTAINING Na+/H+ EXCHANGER REGULATORY FACTOR (NHERF) PROTEINS (2008) (36)
- Extrahepatic portal venous thrombosis: frequent recognition of associated diseases. (1985) (35)
- Benzopyrimido‐pyrrolo‐oxazine‐dione CFTR inhibitor (R)‐BPO‐27 for antisecretory therapy of diarrheas caused by bacterial enterotoxins (2017) (35)
- Chimeric Na+/H+ exchangers: an epithelial membrane-bound N-terminal domain requires an epithelial cytoplasmic C-terminal domain for regulation by protein kinases. (1995) (35)
- The transport of an intact oligopeptide across adult mammalian jejunum. (1986) (35)
- Physical and genetic mapping of a human apical epithelial Na+/H+ exchanger (NHE3) isoform to chromosome 5p15.3. (1993) (34)
- Asymmetric signal transduction in polarized ileal Na(+)-absorbing cells: carbachol activates brush-border but not basolateral-membrane PIP2-PLC and translocates PLC-gamma 1 only to the brush border. (1996) (34)
- Molecular Basis and Differentiation-Associated Alterations of Anion Secretion in Human Duodenal Enteroid Monolayers (2018) (34)
- Propranolol prevention of cholera enterotoxin-induced intestinal secretion in the rat. (1979) (34)
- Ileal microvillar protein villin is tyrosine-phosphorylated and associates with PLC-gamma1. Role of cytoskeletal rearrangement in the carbachol-induced inhibition of ileal NaCl absorption. (1997) (34)
- Intestinal enteroids/organoids: A novel platform for drug discovery in inflammatory bowel diseases (2019) (33)
- NHERF3 (PDZK1) Contributes to Basal and Calcium Inhibition of NHE3 Activity in Caco-2BBe Cells* (2009) (33)
- Drug therapy for diarrheal diseases: a look ahead. (1986) (33)
- Effect of dopamine and bromocriptine on rat ileal and colonic transport. Stimulation of absorption arid reversal of cholera toxin-induced secretion (1983) (32)
- Role of prostaglandins and calcium in the effects of Entamoeba histolytica on colonic electrolyte transport. (1990) (32)
- Ca2+ channel blockers stimulate ileal and colonic water absorption. (1985) (32)
- Translational approaches for pharmacotherapy development for acute diarrhea. (2012) (32)
- The roles of PDZ-containing proteins in PLC-beta-mediated signaling. (2001) (31)
- Two calcium channels in basolateral membranes of rabbit ileal epithelial cells. (1989) (31)
- Premarin-induced ischemic colitis. (1994) (30)
- Brush-border tyrosine phosphorylation stimulates ileal neutral NaCl absorption and brush-border Na(+)-H+ exchange. (1994) (30)
- Does the proteome encode organellar pH? (2006) (30)
- Quantitation of Plasma Membrane Expression of a Fusion Protein of Na/H Exchanger NHE3 and Green Fluorescence Protein (GFP) in Living PS120 Fibroblasts (2000) (30)
- cAMP Stimulates SLC26A3 Activity in Human Colon by a CFTR-Dependent Mechanism That Does Not Require CFTR Activity (2018) (29)
- Fractionation of subcellular membrane vesicles of epithelial and non-epithelial cells by OptiPrep™ density gradient ultracentrifugation. (2014) (29)
- Na+/H+ exchange mediates meal-stimulated ileal absorption. (1994) (28)
- In birds, NHE2 is major brush-border Na+/H+exchanger in colon and is increased by a low-NaCl diet. (1998) (27)
- Fractionation of subcellular membrane vesicles of epithelial and nonepithelial cells by OptiPrep density gradient ultracentrifugation. (2008) (27)
- Chloride Channel (Clc)-5 Is Necessary for Exocytic Trafficking of Na+/H+ Exchanger 3 (NHE3)* (2011) (27)
- Carbachol-induced cytosolic free Ca2+ increases in T84 colonic cells seen by microfluorimetry. (1989) (26)
- PTH transiently increases the percent mobile fraction of Npt2a in OK cells as determined by FRAP. (2009) (26)
- Shiga toxin 1 interaction with enterocytes causes apical protein mistargeting through the depletion of intracellular galectin-3. (2010) (25)
- Elevated Intracellular Calcium Stimulates NHE3 Activity by an IKEPP (NHERF4) Dependent Mechanism (2008) (25)
- Two Histidine Residues in the Juxta-Membrane Cytoplasmic Domain of Na+/H+ Exchanger Isoform 3 (NHE3) Determine the Set Point (2003) (25)
- Regulation of Intestinal Electroneutral Sodium Absorption and the Brush Border Na+/H+ Exchanger by Intracellular Calcium (2009) (25)
- Microfluidics platform for measurement of volume changes in immobilized intestinal enteroids. (2014) (24)
- Myosin VI mediates the movement of NHE3 down the microvillus in intestinal epithelial cells (2014) (24)
- Sorting nexin 27 regulates basal and stimulated brush border trafficking of NHE3 (2015) (24)
- Effects of spironolactone and amiloride on corticosteroid-induced changes in colonic function. (1981) (24)
- Gastrointestinal microphysiological systems (2017) (24)
- Mechanical Stimuli Affect Escherichia coli Heat-Stable Enterotoxin-Cyclic GMP Signaling in a Human Enteroid Intestine-Chip Model (2019) (24)
- NHE2 contains subdomains in the COOH terminus for growth factor and protein kinase regulation. (1999) (24)
- Phospholipase C-γ Binds Directly to the Na+/H+ Exchanger 3 and Is Required for Calcium Regulation of Exchange Activity* (2009) (24)
- The Zn2+-sensing receptor, ZnR/GPR39, upregulates colonocytic Cl- absorption, via basolateral KCC1, and reduces fluid loss. (2017) (23)
- Mucus layer modeling of human colonoids during infection with enteroaggragative E. coli (2020) (23)
- Studies on role of calmodulin in Ca2+ regulation of rabbit ileal Na and Cl transport. (1985) (23)
- Urine electrolyte, mineral, and protein excretion in NHERF-2 and NHERF-1 null mice. (2008) (23)
- Ca2+-calmodulin-, cyclic AMP- and cyclic GMP-induced phosphorylation of proteins in purified microvillus membranes of rabbit ileum. (1984) (23)
- Lysophosphatidic acid induces exocytic trafficking of Na(+)/H(+) exchanger 3 by E3KARP-dependent activation of phospholipase C. (2004) (22)
- NHE3 mobility in brush borders increases upon NHERF2-dependent stimulation by lyophosphatidic acid (2010) (22)
- Effects of methylprednisolone on electrolyte transport by in vitro rat ileum. (1981) (22)
- Pleiotropic ZIP8 A391T implicates abnormal manganese homeostasis in complex human disease (2020) (22)
- Acid and isoproterenol cause serotonin release by acting on opposite surfaces of duodenal mucosa. (1984) (21)
- Current Concepts of Laxative Action: Mechanisms by which Laxatives Increase Stool Water (1979) (20)
- Latrunculin B facilitates Shiga toxin 1 transcellular transcytosis across T84 intestinal epithelial cells. (2008) (20)
- The mammalian Na+/H+ exchanger gene family--initial structure/function studies. (1993) (20)
- Catching the Zebra: Clinical Pearls and Pitfalls for the Successful Diagnosis of Zollinger–Ellison Syndrome (2017) (19)
- Calmodulin Kinase II Constitutively Binds, Phosphorylates, and Inhibits Brush Border Na+/H+ Exchanger 3 (NHE3) by a NHERF2 Protein-dependent Process* (2012) (19)
- Pancreatic cholera syndrome due to a vasoactive intestinal polypeptide-producing tumor: further insights into the pathophysiology. (1988) (19)
- Role of brush border Na+/H+ exchange in canine ileal absorption (1996) (19)
- Ca2+- and calmodulin-dependent protein phosphorylation in rat lacrimal gland. (1982) (19)
- AKT and GSK-3 Are Necessary for Direct Ezrin Binding to NHE3 as Part of a C-terminal Stimulatory Complex (2014) (19)
- Jejunal fluid and electrolyte secretion in carcinoid syndrome (1975) (19)
- NHERF2/NHERF3 Protein Heterodimerization and Macrocomplex Formation Are Required for the Inhibition of NHE3 Activity by Carbachol* (2014) (18)
- Chapter 12 Molecular physiology of mammalian epithelial Na+/H+ exchangers NHE2 and NHE3 (2000) (18)
- Characterization of the synergistic interaction of Escherichia coli heat-stable toxin and carbachol. (1991) (18)
- Differential Association of the Na+/H+ Exchanger Regulatory Factor (NHERF) Family of Adaptor Proteins with the Raft- and the Non-Raft Brush Border Membrane Fractions of NHE3 (2013) (18)
- Alterations in the proteome of the NHERF1 knockout mouse jejunal brush border membrane vesicles. (2010) (18)
- Erratum: A primary human macrophage-enteroid co-culture model to investigate mucosal gut physiology and host-pathogen interactions (2017) (18)
- Cyclic nucleotide‐dependent enzyme secretion in the rat lacrimal gland. (1984) (18)
- Abnormal secretagogue-induced intracellular free Ca2+ regulation in cystic fibrosis nasal epithelial cells. (1992) (17)
- Lysophosphatidic acid stimulation of NHE3 exocytosis in polarized epithelial cells occurs with release from NHERF2 via ERK-PLC-PKCδ signaling. (2014) (17)
- New melanocortin-like peptide of E. coli can suppress inflammation via the mammalian melanocortin-1 receptor (MC1R): possible endocrine-like function for microbes of the gut (2017) (16)
- Cholera toxin inhibits SNX27-retromer-mediated delivery of cargo proteins to the plasma membrane (2018) (16)
- Elevated Calcium Acutely Regulates Dynamic Interactions of NHERF2 and NHE3 Proteins in Opossum Kidney (OK) Cell Microvilli* (2011) (16)
- Effect of Senokot on rat intestinal electrolyte transport. Evidence of Ca++ dependence. (1984) (16)
- Molecular Studies of Members of the Mammalian Na+/H+ Exchanger Gene Family (1996) (16)
- Age-related loss of nongoblet crypt cells parallels decreased secretion in rabbit descending colon. (1988) (16)
- Use of organoids to study regenerative responses to intestinal damage. (2019) (16)
- Mild chronic watery diarrhea-hypokalemia syndrome associated with pancreatic islet cell hyperplasia. Elevated plasma and tissue levels of gastric inhibitory polypeptide and successful management with nicotinic acid. (1979) (16)
- Gastrointestinal transport : molecular physiology (2001) (16)
- Electrolyte transport in piglets infected with transmissible gastroenteritis virus (1991) (16)
- NHE3 Activity Is Dependent on Direct Phosphoinositide Binding at the N Terminus of Its Intracellular Cytosolic Region* (2010) (16)
- Elevated intraluminal pressure alters rabbit small intestinal transport in vivo. (1982) (16)
- Calcium and calmodulin‐dependent protein phosphorylation in rabbit ileum (1981) (16)
- Mechanism of fluid and electrolyte secretion in the germ-free rat cecum (1979) (15)
- Role of calcium and calmodulin in the regulation of the rabbit ileal brush-border membrane Na+/H+ antiporter (1989) (15)
- Role of calcium in cholinergic stimulation of lacrimal gland protein secretion. (1985) (15)
- Effects of calcium antagonist TMB-8 on active Na and Cl transport in rabbit ileum. (1986) (15)
- Enterohemorrhagic E. coli (EHEC)—Secreted Serine Protease EspP Stimulates Electrogenic Ion Transport in Human Colonoid Monolayers (2018) (15)
- cAMP-mediated inhibition of the epithelial brush border NayH exchanger, NHE3, requires an associated regulatory protein (sodium–hydrogen antiporterypH regulationysignal transductionyNa1 absorption) (1997) (15)
- Magnesium-induced diarrhea and new insights into the pathobiology of diarrhea. (1991) (14)
- Intestinal filtration-secretion due to increased intraluminal pressure in rabbits. (1982) (14)
- NHERF2 Protein Mobility Rate Is Determined by a Unique C-terminal Domain That Is Also Necessary for Its Regulation of NHE3 Protein in OK Cells* (2013) (14)
- NHERF2 increases platelet-derived growth factor-induced proliferation through PI-3-kinase/Akt-, ERK-, and Src family kinase-dependent pathway. (2004) (14)
- Refractory lymphocytic enterocolitis and tumor necrosis factor antagonist therapy. (2010) (13)
- DIABETES WITHOUT GLUCAGON (1976) (13)
- Induction of the metal transporter ZIP8 by interferon gamma in intestinal epithelial cells: Potential role of metal dyshomeostasis in Crohn's disease. (2019) (13)
- Challenges in IBD Research: Novel Technologies. (2019) (13)
- The NHE3 Juxtamembrane Cytoplasmic Domain Directly Binds Ezrin: Dual Role in NHE3 Trafficking and Mobility in the Brush Border (2006) (13)
- Phenylquinoxalinone CFTR activator as potential prosecretory therapy for constipation (2017) (13)
- Effects of galanin on short circuit current and electrolyte transport in rabbit ileum (1994) (13)
- Identification of PTH-responsive Na/H-exchanger isoforms in a rabbit proximal tubule cell line (RKPC-2) (1993) (13)
- Inhibition of transport processes of intestinal segments following augmentation enterocystoplasty in rats. (1996) (13)
- Dantrolene and basal ileal sodium and chloride transport: involvement of calcium stores. (1983) (13)
- Enteric neural pathways inhibitory to rabbit duodenal serotonin release. (1984) (12)
- Magnesium Hydroxide: New Insights Into the Mechanism of its Laxative Effect and the Potential Involvement of Prostaglandin E2 (1992) (12)
- Patients' perspectives on the derivation and use of organoids (2021) (12)
- Increased tear secretion in pancreatic cholera: a newly recognized symptom in an experiment of nature. (1988) (12)
- Fluid Shear Stress Enhances Differentiation of Jejunal Human Enteroids in Intestine-Chip. (2020) (12)
- Effect of altered intestinal water transport on rabbit ileal blood flow. (1979) (12)
- Identifying the localization and exploring a functional role for Gprc5c in the kidney (2017) (12)
- Both NHERF3 and NHERF2 are necessary for multiple aspects of acute regulation of NHE3 by elevated Ca2+, cGMP, and lysophosphatidic acid. (2018) (12)
- Phosphodiesterase 5 (PDE5) restricts intracellular cGMP accumulation during enterotoxigenic Escherichia coli infection (2020) (11)
- Quantitative contribution of NHE 2 and NHE 3 to rabbit ileal brush-border Na 1 / H 1 exchange (1998) (11)
- L-Glutamine in intestinal sodium absorption: lessons for physiology, pathobiology, and therapy for diarrhea. (1994) (11)
- Gastrointestinal Influences on Hydrogen Ion Balance (2005) (11)
- Methylprednisolone stimulation of guanylate cyclase activity in rat small intestinal mucosa: Possible role in electrolyte transport (1981) (11)
- G protein-coupled receptors in gastrointestinal physiology. III. Asymmetry in plasma membrane signal transduction: lessons from brush-border Na+/H+ exchangers. (1998) (11)
- Insulin-Like Growth Factor 1 (IGF-1) Enhances the Protein Expression of CFTR (2013) (11)
- Current and potential future applications of human stem cell models in drug development. (2020) (10)
- Regulation of the transfected Na+/H+-exchanger NHE3 in MDCK cells by vasotocin (1997) (10)
- Phosphorylation of NHE3-S719 regulates NHE3 activity through the formation of multiple signaling complexes (2017) (10)
- PLC-γ directly binds activated c-Src, which is necessary for carbachol-mediated inhibition of NHE3 activity in Caco-2/BBe cells. (2013) (10)
- Significance of Abnormal Rabbit Ileal Histology in the Pathogenesis of Diarrhea (1979) (9)
- Effect of dopamine and bromocriptine on rat ileal and colonic transport. Stimulation of absorption and reversal of cholera toxin-induced secretion. (1983) (9)
- Coming out of the NHERF family (2005) (9)
- Nonsynonymous single nucleotide polymorphisms of NHE3 differentially decrease NHE3 transporter activity. (2015) (9)
- The NHERF2 sequence adjacent and upstream of the ERM-binding domain affects NHERF2–ezrin binding and dexamethasone stimulated NHE3 activity (2015) (9)
- Epithelial WNT2B and Desert Hedgehog Are Necessary for Human Colonoid Regeneration after Bacterial Cytotoxin Injury (2018) (8)
- Pharmacotherapy of diarrheal diseases: an approach based on physiologic principles. (1984) (8)
- Pancreatic insufficiency and congenital rubella syndrome. (1975) (8)
- Chronic Inflammation in Ulcerative Colitis Causes Long-Term Changes in Goblet Cell Function (2021) (8)
- NHE2 contains subdomains in the COOH terminus for growth factor and protein kinase regulation. (1999) (7)
- Ca2+ channel blockers interact with alpha 2-adrenergic receptors in rabbit ileum. (1988) (7)
- NHERF3 is Necessary for E. coli Heat Stable Enterotoxin (ST)-induced Inhibition of NHE3 - Differences in Signaling in Mouse Small Intestine and Caco-2 Cells. (2019) (7)
- Pathophysiological mechanisms of diarrhoeal diseases: diverse aetiologies and common mechanisms. (1983) (7)
- PDZ domain-dependent regulation of NHE3 protein by both internal Class II and C-terminal Class I PDZ-binding motifs (2017) (7)
- Chloroquine stimulates absorption and inhibits secretion of ileal water and electrolytes. (1982) (6)
- Organoid-derived Duodenum Intestine-Chip for preclinical drug assessment in a human relevant system (2019) (6)
- Suggestion of a role for calmodulin and phosphorylation in regulation of rabbit ileal electrolyte transport: effects of promethazine. (1986) (6)
- Ca2+ - and cAMP-induced protein phosphorylation in lacrimal gland basolateral membranes. (1988) (6)
- Secretory hormones of Entamoeba histolytica. (1985) (6)
- Inhibition of CFTR‐mediated intestinal chloride secretion as potential therapy for bile acid diarrhea (2019) (5)
- Uncoupling of phospholipase C from receptor regulation of [Ca2+]i in T84 colonic cells by prolonged exposure to phorbol dibutyrate. (1991) (5)
- Vanishing pancreatic calcifications. A nonspecific finding in chronic pancreatitis. (1974) (5)
- Cytosol free Ca++ in the regulation of active intestinal Na and Cl transport. (1984) (5)
- Effect of cycloheximide on corticosteroid-induced changes in colonic function. (1982) (5)
- Alterations in the proteome of the NHERF2 knockout mouse jejunal brush border membrane vesicles. (2011) (5)
- No effect of propranolol on chronic diarrhea. (1979) (5)
- Differential effects of PDZ-Adapterprotein NHERF1, E3KARP and PDZK1 knockout on the regulation of NHE3 transport activity in native murine colonic epithelium (2006) (5)
- Alterations in the proteome of the NHERF 1 knockout mouse jejunal brush border membrane vesicles (2010) (5)
- Pancreatic ascites. (1974) (5)
- Effect of chronic elevation of blood serotonin on intestinal transport (1976) (4)
- Erratum: cAMP-mediated inhibition of the epithelial brush border NA+/H+ exchanger, NHE3, requires an associated regulatory protein (Proceedings of the National Academy of Sciences of the United States of America (April 1, 1997) 94 (3010-3015)) (1997) (4)
- Small intestinal and colonic linked sodium chloride absorption. New understanding of distribution and regulation. (1987) (4)
- Calcium/calmodulin dependent protein kinase II constitutively binds and regulates the ileal BB Na+/H+ exchanger NHE3 (2003) (4)
- Factors and molecular mechanisms involved in the regulation of chicken colonic luminal membrane Na(+)-linked transport systems. (1996) (4)
- Regulatory mechanisms of cloned Na+/H+ exchangers involve change in the amount of plasma membrane exchanger: Use of cell surface biotinylation (1998) (4)
- Loss of PI3-kinase activity of inositol polyphosphate multikinase impairs PDK1-mediated AKT activation, cell migration and intestinal homeostasis (2020) (4)
- 730 Cyclic GMP Kinase II (CKII) Inhibits NHE3 by Affecting Trafficking via Phosphorylating NHE3 At Three Sites: Identification of a Multifunctional Phosphorylation Site (2013) (4)
- Protein phosphorylation and the control of intestinal electrolyte transport. (1984) (3)
- SARS-COV-2 induced Diarrhea is inflammatory, Ca2+ Dependent and involves activation of calcium activated Cl channels (2021) (3)
- E3KARP (NHE3 kinase a anchoring protein) is necessary for cGMP regulation of NHE3: Demonstration of a plasma membrane signaling complex containing NHE3, E3KARP, and cGMP kinase II (2001) (3)
- 4 A Peptide Mimicking the NHE3 C-Terminus Stimulates Basal and Blocks CA2+ and cAMP Inhibition of NHE3 Activity, and Prevents Cholera Toxin-Induced Mouse Jejunal Fluid Accumulation: Potential Role as Drug Therapy for Diarrhea (2012) (3)
- Ileal Microvillar Protein Villin Is Tyrosine-phosphorylated and Associates with PLC-γ1 (1997) (3)
- A common NHE3 single-nucleotide polymorphism has normal function and sensitivity to regulatory ligands. (2017) (3)
- cGMP-dependent kinase 2, Na+/H+ regulatory factor 2, and Na+/H+ exchanger isoform 3 assemble within lipid rafts in murine small intestinal brush border membrane (2013) (3)
- Serotonin (5HT)-induced ileal secretion: Active electrolyte secretion which is calcium dependent (1979) (3)
- Quantitative contribution of NHE2 and NHE3 to rabbit ileal brush-border Na+/H+exchange. (1998) (3)
- Cholinergic-induced anion secretion in murine jejunal enteroids involves synergy between muscarinic and nicotinic pathways. (2020) (3)
- 541 Rotavirus Infection in Patients Is Associated With Altered Trafficking of Apical Membrane Transport Proteins (2016) (3)
- Methylprednisolone stimulation of guanylate cyclase activity in rat ileal mucosa (1978) (3)
- Relation between enteric hormones and intestinal function in the WDHA syndrome (1978) (3)
- A NHE3-related pseudogene is on human chromosome 10; the functional gene maps to 5p15.3. (1996) (3)
- Identification of Intestinal NaCl Absorptive-Anion Secretory Cells: Potential Functional Significance (2022) (3)
- Small intestinal and colonic linked sodium chloride absorption (1987) (2)
- Use of Human Tissue Stem Cell-Derived Organoid Cultures to Model Enterohepatic Circulation. (2021) (2)
- TMEM16A and NHERF1 Regulate Ca2+ and cAMP Stimulated Cl‐ Secretion in Murine Colon (2012) (2)
- 749 Nherf2 Is Necessary for Basal and All Second Messenger Regulation of NHE3 Activity in Intact Mouse Ileal Na Absorptive Cells (2008) (2)
- [Ca2+]i independent mitogenesis in cultured human fibroblasts revealed by single cell microfluorimetry. (1989) (2)
- Enterotoxigenic E. Coli (ETEC) Pathogenesis Modeled in Human Enteroid Monolayers Demonstrates MRP-Related Cyclic Nucleotide Secretion (2017) (2)
- Effect of methylprednisolone treatment on ion transport in rat ileum in vitro (1977) (2)
- 266 NHE3 IS A DRUG TARGET FOR TREATING DIARRHE; A NOVEL PEPTIDE STIMULATES NHE3 ACTIVITY, PREVENTS CAMP, CGMP AND CA2+ INHIBITION OF NHE3 AND PREVENTS CHOLERA TOXIN AND E. COLI STABLE ENTEROTOXIN FLUID SECRETION. (2021) (2)
- Methylprednisolone stimulation of guanylate cyclase activity in rat small intestinal mucosa: possible role in electrolyte transport. (1981) (2)
- 110 Missense Mutations of SLC9A3 in Patients With Congenital Sodium Diarrhea Are Associated With Reduced Na+/H+ Exchanger 3 (NHE3) Activity: Identification of the Cause of the Phenotype (2015) (2)
- Squalamine, a novel cationic steroid, specifically inhibits the brush-border Na+/H+ exchanger isoform NHE3. (1999) (2)
- The epithelial brush-border Na/H Exchanger NHE3 associates with the actin cytoskeleton by binding to ezrin directly and via PDZ domain containing NHERF proteins (2007) (2)
- S1770 Proteome of the Small Intestinal Brush Border of the NHERF1 Knock Out Mouse: Up Regulation of Transporters and Pro-Proliferation Molecules (2008) (2)
- The Ethics of Living-Donor Liver Transplantation (2007) (2)
- Promethazine stimulates NaCl absorption and inhibits Ca++-calmodulin-dependent phosphorylation (P) in rabbit ileum at the same low concentrations suggesting a role for P in NaCl transport (1985) (2)
- Ileal brush border actin-binding protein villin associates with the brush border sodium-hydrogen exchanger, NHE3 (1998) (2)
- Towards understanding mechanisms underlying EHEC-induced transcellular transport of nano-objects across an intestinal epithelial barrier: P-247. (2011) (2)
- Shigella dysenteriae I enterotoxin: A unique myoelectric response of the small intestine (1978) (1)
- Erratum: Serum regulates Na+/H+ exchange in Caco-2 cells by a mechanism which is dependent on F-actin (Journal of Biological Chemistry (1992) 267 (956-962)) (1993) (1)
- Enterotoxigenic Escherichia coli-blood group A interactions intensify diarrheal severity. (2019) (1)
- Serotonin (5HT)-induced active ileal secretion: Evidence of calcium dependence (1979) (1)
- Food-borne and water-borne infections and the gastroenterologist. (1999) (1)
- Case 35-1988: A 63-Year-Old Asplenic Man with Myelofibrosis, Fever, and Bloody Diarrhea (1988) (1)
- Immunolocalization of ammonium ion transporters in gill mitochondria-rich cells of the terrestrial mudskipper fish, Periophthalmodon schlosseri (1999) (1)
- Structure-function studies of membrane domain-cytoplasmic domain and membrane domain-membrane doman chimeras of Na+/H+ exchanger isoforms NHE1 and NHE3 (1998) (1)
- Propranolol inhibition of cholera toxin induced intestinal secretion in the rat (1977) (1)
- 749 LPA/LPA5 Receptor Stimulation of NHE3 Involves Two Separate Events: Stimulation of NHE3 Exocytosis via EGFR and ERK and Dynamic Dissociation of NHE3 From the Microvillar (MV) Cytoskeleton/NHERF2 via PLC and a Novel PKC (2012) (1)
- Practical Advice From a Basic and Translational Researcher at a Major Medical School (2016) (1)
- Mechanical Stimuli Affect E. Coli Heat Stable Enterotoxin (ST)-Cyclic GMP Signaling in a Human Enteroid Intestine-Chip Diarrhea Model (2019) (1)
- Measurements of Paracellular Water Flow in the Intestinal Epithelial CACO-2 and T84 Cells in Isotonic Conditions and Upon a Treatment With Anti-Constipation Drug Lubiprostone (2011) (1)
- Na(+)/H(+) exchangers (NHE1-3) have similar turnover numbers but different percentages on the cell surface. (1999) (1)
- Ca/sup + +/- and cyclic AMP-induced changes in intact cell phosphorylation of ileal microvillus membrane proteins (1986) (1)
- 744 Phospholipase Cγ (PLCγ) Directly Binds to the Na+/H+ Exchanger 3 (NHE3) C-Terminus Which Is Necessary for Basal and Calcium-Mediated Inhibition of NHE3 Activity (2008) (1)
- G Protein-Coupled Receptors in Gastrointestinal Physiology III. Asymmetry in plasma membrane signal transduction: lessons from brush-border Na1/H1 exchangers* (1998) (1)
- Effect of spironolactone on mineralo and glucocorticoid — induced increases in colonic NA and water absorption and Na-K-ATPase activity (1978) (1)
- The Glycosphingolipid Gb3 in Metastatic Transformation of Colon Cancer (2005) (1)
- Expression and regulation of a fusion protein of naih exchanger NHE3 and green fluorescent protein in epithelial Caco-2 cells (2000) (1)
- Thomas Russell Hendrix, MD, October 17, 1920 – December 23, 2013 (2014) (1)
- 190 Human Small Intestinal Enteroids Enable Mechanistic Studies of cAMPInduced Changes in Intracellular pH (2014) (1)
- A NHE3-related pseudogene is on human Chromosome 10; the functional gene maps to 5pl5.3 (1996) (1)
- Cyclic AMP and Ca2+/calmodulin dependent protein phosphorylation in rat lacrimal gland basolateral membranes (1984) (1)
- 728 Zinc Stimulates Intestinal Na/H Exchanger 3 (NHE3) via Trafficking Effects in a Phospholipase C (PLC) Dependent Manner (2013) (0)
- In Vitro Modeling of Human Enterohepatic Circulation Using Stem Cell-Derived Ileal Enteroids and Primary Cultures of Hepatocytes (2017) (0)
- Proteome of murine jejunal brush border membrane vesicles (Journal of Proteome Research (2007) 6, 10, (4068-4079)) (2008) (0)
- Cholinergic influence upon acid-stimulated serotonin release from duodenum (1981) (0)
- Shiga toxin 1 transcellular transcytosis across T 84 intestinal epithelial cells (2008) (0)
- 269 - A Novel Model of Human Enteroids in the Intestine-Chip (I-C) Platform that Includes Dynamic Flow and Cyclic Strain for Physiological and Phamacological Studies of Intestinal Ion Transport (2018) (0)
- Has a physiologic function for NHE2 finally been identified? (2022) (0)
- Issue Information (2001) (0)
- New drug treatment for diarrhoea. (1990) (0)
- The cGMP-dependent kinase 2 is recruited to and colocalizes with Na+/H+ regulatory factor 2 and Na+/H+ exchanger isoform 3 during guanylate cycle C receptor activation in murine small intestinal brush border membrane in vivo (2014) (0)
- 34 – E.Coli Heat Stable Enterotoxin (ST) Inhibition of Nhe3 Occurs by Different Signaling Pathways Downstream of Cyclic Gmp in Murine Jejunum and Caco-2 Cells: A Warning About Assumed Equivalence (2019) (0)
- 537 NHERF2-NHERF3 Scaffolded Macrocomplex Is Necessary for E. coli Heat Stable Enterotoxin (STa)- Induced Intestinal Fluid Secretion (2016) (0)
- Su1573 – Cholinergic-Induced Anion Secretion in Mouse Jejunal Enteroids is Regulated Through Synergy Between Intrinsic Enterocyte Muscarinic and Nicotinic Receptors (2019) (0)
- Su1200 A Common NHE3 Non-Synonymous Polymorphism (C2405T/R799C) has Normal Transport Function and Similar Sensitivity to the Orally Active NHE3 Inhibitor, Tenapanor (2016) (0)
- 1015 A Novel Ser-Rich Motif in the NHE3 C-Terminal Regulatory Domain is Required for Stimulation of Na/H Exchange Activity by AKT as Well as for Direct Ezrin Binding to NHE3 (2010) (0)
- 23 - Human Colonoid Regeneration is Guided by Desert Hedgehog and WNT2B after Injury by Enterohemorrhagic E. Coli (EHEC) Secreted Serine Protease ESPP (2018) (0)
- W1274 Macropinocytosis Is Involved in Shiga Toxin 1 Uptake and Transcytosis By Gb3-Negative Human Intestinal Epithelial Cells (2008) (0)
- 27 Neutral Na+ Absorption and Fluid/Anion Secretion Are Not Separated Processes in the Human Enteroid Model (2015) (0)
- Su1199 Post-Transcriptional Regulation of Na-H Exchanger-3 (NHE3) by Aldosterone Involves microRNA-204 (2016) (0)
- Mo1824 Asymmetric Brush Border Activation of Phospholipase D is Necessary for Carbachol Inhibition of NHE3 Activity (2012) (0)
- 977 Human Colonoids As a Model for Shiga Toxin Producing E. coli (STEC)-Induced Intestinal Epithelial Injury and Regeneration (2016) (0)
- Development of an endogenous epithelial Na(+)/H(+) exchanger (NHE3) in three clones of caco-2 cells. (1999) (0)
- 1014 SRC Dynamically Associates With PLC-γ and is Necessary for CA2+-Mediated Inhibition of NHE3 Activity in CACO-2/BBE Cells (2010) (0)
- Role of PDZ roteins NHERF and E3KARP in cyclic nucleotide regulation of NHE3 (2000) (0)
- Air-Liquid-Interface Reorganizes Membrane Lipid and Enhance Recruitment of Slc26a3 to Lipid-Rich Domains in Human Colon (2022) (0)
- Chronic exposure of ErbB TKIs inhibits DRA expression and activity through an ERK/Elk-1/CREB/AP-1 dependent pathway (2020) (0)
- NHERF1 Knock out Mice Have Abnormal Tight Junctions and Increased Severity of B. Fragilis Enterotoxin Related Colitis Associated With Reduced Expression of Claudins 2 and 4 (2011) (0)
- 886 Do Mutations of NHE3 At the Site of Poorly Functioning NHE3 Polymorphisms Contribute to Diarrhea of Congenital Na Diarrhea (2009) (0)
- Regulation of the epithelial brush border Na/H exchanger NHE3, a story of cytoskeleton and signaling complexes (2010) (0)
- Faculty Opinions recommendation of Crystal structure of CHP2 complexed with NHE1-cytosolic region and an implication for pH regulation. (2006) (0)
- Tu1268 THE INFLAMMATORY SIGNATURE OF HUMAN ENTEROIDS DERIVED FROM ULCERATIVE COLITIS PATIENTS IS MAINTAINED DURING LONGTERM PASSAGE (2020) (0)
- T1853 NHERF1 and NHERF2 Separately Contribute to Basal and Acutely Regulated NHE3 Activity. An Exception is cAMP Inhibiton Which Can Be Mediated Either by NHERF1 or NHERF2 (2010) (0)
- Farnesoid X receptor activation inhibits colonic epithelial CFTR expression ‐ a new target for antidiarrheal therapy? (2013) (0)
- NHE3 contains a cleavable signal peptide followed by 11 membrane spanning domains: New insights into topology (2000) (0)
- Evidence of an essential role of NHERF1 and NHEF2 in G‐protein coupled receptor regulation of CFTR‐mediated intestinal anion secretion in vivo (2009) (0)
- Glucocorticoid-Mediated Increase in NHE3 Synthesis, Membrane Trafficking and Function is Differentially Impaired in NHERF2 Ko and NHERF3 (PDZK1) Ko Ileum (2011) (0)
- Adipokine C1q/Tumor Necrosis Factor- Related Protein 3 (CTRP3) Attenuates Intestinal Inflammation Via Sirtuin 1/NF-κB Signaling (2022) (0)
- The NHE3 interacting PDZ protein NHERF2 determines the lipid raft association of the apical Na+/H+ exchanger NHE3 in murine small intestine (2012) (0)
- 189 Basal and Stimulated BB NHE3 Activity Requires Intracellular SNX27, a PDZDomain Containing Binding Partner of NHE3 That Regulates Endosome to Plasma Membrane Trafficking (2014) (0)
- Contents, Vol. 4, 1994 (1994) (0)
- Ileal secretion causes choleresis in the rabbit: A new contributor to diarrhea? (1978) (0)
- Secretagogues of Entamoeba histolytica: role in diarrhoea. (1988) (0)
- Protein kinase C (PKC) is involved in translocation of endogenous apical NA/H exchanger (NHE3) in human colonic adenocarcinoma cells CACO-2 (1997) (0)
- Presidential address. (2007) (0)
- T1871 NHE3 Activity is Dependent on Direct Phosphatidylinositide Binding at Its Proximal Cytosolic Region (2010) (0)
- 256 Myosin VI is Responsible for Movement of NHE3 From the Microvillus of Polarized Caco-2-bbe Cells to the Intervillus Clefts Under Basal Conditions and With Ca2+ Stimulated Endocytosis (2010) (0)
- Altered myoelectric activity of the small intestine in response to live Shigella dysenteriae: A toxin-mediated response (1978) (0)
- A Novel GPCR in the Renal Proximal Tubules, Gprc5c, Is Involved in Systemic pH Regulation (2016) (0)
- Measurement of cytosol free calcium in single intestinal epithelial cells a study using a fluorescence microscopy imaging system (1987) (0)
- T1867 Proteome of the Small Intestinal Brush Border of the NHERF2 Knock out (Ko) Mouse: Changes in Transporters and Signaling Molecules (2010) (0)
- Mo1766 Mucus Produced by Stem Cell Derived Human Colonoids Is an Early Target in Enterohemorrhagic E. coli Infection (2015) (0)
- 521 - Morphologic and Intestinal Stem Cell Gene Expression Changes in Crispr-Edited APC KO Human Colonoids (2018) (0)
- Effect of dantrolene on active rabbit ileal electrolyte transport. Evidence for role of intracellular calcium stores in basal transport (1982) (0)
- Increased Tear Secretion in a Patient with Pancreatic Cholera (1987) (0)
- Constitutively active phosphatidlyinositol 3-kinase (Pl 3-K) and Akt are sufficient to stimulate NHE3: Insights in mechanisms of NHE3 stimulation (2001) (0)
- 592 HUMAN INTESTINAL STEM CELL (ISC)-DERIVED ENTEROIDS/COLONOIDS (HIE/HIC) FROM IBD PATIENTS DIFFERENTIALLY RESPOND TO CYTOKINES COMPARED TO ENTEROIDS FROM HEALTHY DONORS (2020) (0)
- 713 - A New Intestine-Chip Model to Study Human Intestinal Physiology and Pathophysiology (2018) (0)
- Su1039 – Human Differentiated Enteroid Monolayers Exhibit Egfr/Mek- and Nf-Kb-Dependent Plasticity in a Model of Intestinal Trauma (2019) (0)
- Presentation of the AGA Distinguished Achievement Award in Basic Science to Kim E. Barrett, PhD, AGAF. (2021) (0)
- 756 - Enterohemorrhagic E. Coli (EHEC) Secreted Serine Protease Espp, Stimulates Active Electrogenic Ion Transport in Human Colonoid Monolayers (2018) (0)
- The Na+/H+ exchanger NHE1 and the lactate-H+ cotransporter MCT1 are spatially organized in C6 gliomas in rat brain. (2010) (0)
- T1727 Myosin Vi Is Necessary for Setting Brush Border NHE3 Activity: An Effect On NHE3 Trafficking/Endocytosis (2009) (0)
- The NHERF2 Dependent Dynamic Ca2+/LPA Regulation of NHE3 Mobility and Interaction At the Epithelial Brush Border (2010) (0)
- SLC26A3 (DRA) is stimulated in a synergistic, intracellular Ca2+ dependent manner by cAMP AND ATP in intestinal epithelial cells (2022) (0)
- Sa1084 MUSCARINIC AND NICOTINIC SIGNALING SYNERGISTICALLY REGULATE CHOLINERGIC-INDUCED ANION SECRETION THAT INVOLVES BOTH CACC AND CFTR IN THE MOUSE JEJUNAL ENTEROIDS (2020) (0)
- Cholera Toxin Destabilizes Retromer to Inhibit NA+/H+ Exchanger3 Activity in Intestinal Epithelial Cells- Possible Therapeutic Role of a Retromer Stabilizer in Treating Diarrhea (2017) (0)
- cGMP-dependent kinase 2, Na+/H+ regulatory factor 2, and Na+/H+ exchanger isoform 3 assemble within lipid rafts in murine small intestinal brush border membrane (2013) (0)
- W1661 Reduced Stimulation of NHE3 Activity and Reduced Exocytosis with Knockdown of Clc-5, An Endosomal Chloride Channel (2009) (0)
- D-Glucose Acts via SGLTI to Increase NHE 3 in Mouse Jejunal Brush Border by a NHERF 2-Dependent Process (2011) (0)
- 31 – Endosomal Snx17 Sets the Plasma Membrane Amount of Nhe3 and Prevents Its Degradation by Binding to the Nhe3 Cterminus (2019) (0)
- Su1203 The Plasticity of the Intestinal Stem Cell Compartment and Its Induction Following Rotavirus Infection (2016) (0)
- The lateral mobility of NHE3 on the apical membrane of polarized epithelial cells is limited by binding to PDZ domain proteins NHERF1/2 as determined by fluorescence recovery after photobleaching (FRAP) (2003) (0)
- Table of Contents (1991) (0)
- Sa1413 Enterohemorrhagic E. coli (EHEC)-Secreted Serine Protease EspP is an Enterotoxin and Stimulates Anion Secretion in Human Stem Cell Derived Colonoid Monolayers (2016) (0)
- 34 Human Intestinal Epithelial Response to Gastrointestinal Virus Infection Using Enteroids (2015) (0)
- Do Diverse Mechanisms of Pathogenesis Lead to Final Common Pathways ? (2012) (0)
- T1841 Differential Effect of NHE3 Kinase a Regulatory Protein (E3karp/NHERF2) Knockout on cAMP-, cGMP-, or [Ca2+]-Induced Inhibition of Na+/H+ Exchanger 3 (NHE3) Activity Along the Murine Intestinal Tract (2010) (0)
- Mo1790 The NHE3 C-Terminal Stimulatory Complex Acts by Changes in Its Phosphorylation and Dynamic Association With Direct Ezrin Binding (2013) (0)
- Interaction between Ca/sup + +/-channel antagonists and. cap alpha. /sub 2/-adrenergic receptors in rabbit ileal cell membrane (1986) (0)
- Mo1751 CGMP-Dependent Kinase 2, Na+/H+ Regulatory Factor 2, and Na+/H+ Exchanger Isoform 3 Dynamically Assemble Within Lipid Rafts in Murine Small Intestinal Brush Border Membrane (2014) (0)
- Chloroquine diphosphate reverses cholera toxin-induced ileal secretion in the rat (1980) (0)
- Ileal and Colonic Enteroids as a Model for Studying FXR Regulation of the Enterohepatic Circulation in Humans (2020) (0)
- CK2 Phosphorylation of NHE3-S 719 Regulates NHE3 Activity by Organizing the C-Terminus to form Multiple Signaling Complexes and Establish Lipid Raft Distribution (2017) (0)
- Tu1577: SORTING NEXIN-27 REGULATES THE ROUTE OF APICAL MEMBRANE TRAFFICKING OF DRA BY PREVENTING RETROGRADE TRAFFICKING IN INTETNAL EPITHELIAL CELLS (2022) (0)
- 430 - Epithelial-Secreted WNT Ligands are Essential Drivers of Intestinal Stem Cell Response to Virus-Induced Villus Damage (2018) (0)
- 551 Shiga Toxin 1 Uptake By Intestinal Epithelial Cells Is CDC-42 Mediated and Clathrin-Independent (2009) (0)
- Fr149 CHOLERA TOXIN DISRUPTS CELL CYCLE HOMEOSTASIS IN CRYPT-LIKE HUMAN ENTEROIDS (2021) (0)
- Faculty Opinions recommendation of Mechanism of IFN-gamma-induced endocytosis of tight junction proteins: myosin II-dependent vacuolarization of the apical plasma membrane. (2005) (0)
- Erratum: Enterotoxigenic Escherichia coli-blood group a interactions intensify diarrheal severity (Journal of Clinical Investigation (2018)128(8)(3298-3311)Doi:10.1172/JCI97659) (2018) (0)
- Deficits in Enterocyte Apical Transporters Associated with Loss of Myosin VB (2017) (0)
- Renal Role of Gprc5c in Regulating Systemic pH Homeostasis (2017) (0)
- Adipokine C1q/Tumor necrosis factor-Related Protein 3 (CTRP3) Attenuates Intestinal Inflammation via Histone Deacetylase Sirtuin 1 (SIRT1)/NF-κB Signaling (2022) (0)
- Mo1816 The NHE3 Interacting PDZ Protein NHERF2 is Strongly Lipid Raft-Associated and Determines the Raft Association of the Apical Na+/H+ Exchanger NHE3 in Murine Small Intestinal Brush Border Membrane (2012) (0)
- S1759 NHE3 and NHERF2 Bind Dynamically At the Epithelial Brush Border in Response to Elevated Ca2+, Revealed By FRET (2009) (0)
- Cloning and Expression of a Rabbit cDNA Encoding a Serum-activated (1993) (0)
- Separate functions for brush border membrane and endosomal NHE3 in a polarized epithelial cell line (2000) (0)
- New melanocortin-like peptide of E. coli can suppress inflammation via the mammalian melanocortin-1 receptor (MC1R): possible endocrine-like function for microbes of the gut (2017) (0)
- mOrange2, a Genetically Encoded, pH Sensitive Fluorescent Protein, is an Alternative to BCECF-AM to Measure Intracellular pH to Determine NHE3 and DRA Activity. (2022) (0)
- Basic Fibroblast Growth Factor Stimulates Surface Expression and Activity of Na 1 / H 1 Exchanger NHE 3 via Mechanism Involving Phosphatidylinositol 3-Kinase * (2000) (0)
- Na+/H+ exchanger NHE3 interacts with PDZ domains of the regulatory proteins, E3KARP and NHERF (1998) (0)
- Ileal secretion of water and electrolytes induced by acute elevation of intraluminal hydrostatic pressure (1978) (0)
- Evidence for a Nhe3 Related Pseudogene on Human Chromosome-10 (1995) (0)
- CAM Kinase IIγ Inhibits Activity and Directly Binds the C-Terminal Domain of the Intestinal Brush Border Na/H Exchanger NHE3 in a Dymanic, Ca2+ Dependent Manner (2011) (0)
- Enterohemorrhagic E. coli (EHEC) Secreted Serine Protease EspP‐Induced Injury and Regeneration is Guided by Desert Hedgehog and WNT2B in Human Colonoids (2020) (0)
- Faculty Opinions recommendation of Impaired gastric acid secretion in mice with a targeted disruption of the NHE4 Na+/H+ exchanger. (2005) (0)
- Mo1654 Decreased Intestinal NHE3 Expression by mTOR Inhibition and Its Implication in Rapamycin Related Diarrhea in Renal Transplant Recipients (2012) (0)
- 35 - Anion Secretion is Quantitatively Rather than Qualitatively Different Between Crypt-Like Undifferentiated and Villuslike Differentiated Human Duodenal Enteroid Monolayers (2018) (0)
- Differences in plasma membrane half-life and membrane trafficking of the epithelial Na+/H+exchangers NHE2 and NHE3: Insights into functions of these proteins (2000) (0)
- Mo1945 Human Intestinal Enteroids As a Model System for the Study of Enteric Virus Pathogenesis (2014) (0)
- Subject Index, Vol. 4, 1994 (1994) (0)
- Fr584 MUSCARINIC AND NICOTINIC PATHWAYS SYNERGISTICALLY REGULATE CHOLINERGIC-INDUCED ANION SECRETION BY NICOTINIC-INDUCED CROSS-OVER OF CA2+ AND CAMP SIGNALING IN MOUSE JEJUNAL ENTEROIDS (2021) (0)
- 584 DYNAMIC INTERACTIONS AMONG CFTR, NHERF4 (NF4) AND DRA (SLC26A3) ARE RESPONSIBLE FOR CHOLERA TOXIN/FORSKOLIN (CTX/FSK) STIMULATION OF DRA ACTIVITY AND INVOLVE PROTEIN TRAFFICKING AND CFTR-DRA INTERACTIONS (2020) (0)
- Human duodenal bicarbonate absorption involves both brush border NA+/H+ exchangers NHE2 and NHE3 (2000) (0)
- Shigella enterotoxin stimulated intestinal secretion is not mediated by cyclic adenosine monophosphate (cAMP) (1974) (0)
- AGA InstitutePresidential Address (2007) (0)
- 822: CALCIUM-SENSING RECEPTOR ACTIVATOR CINACALCET REDUCES CHLORIDE AND FLUID SECRETION IN MOUSE AND HUMAN INTESTINAL ORGANOID MODELS OF SECRETORY DIARRHEA (2022) (0)
- Lysophosphatidic acid stimulates the brush border Na/H exchanger NHE3 in Na absorptive epithelial cells by increasing exocytic trafficking by a PI 3-kinase dependent mechanism that requires E3KARP (2003) (0)
- Human enteroids: preclinical models of non-inflammatory diarrhea (2013) (0)
- NHE2 is the major brush border NA/H exchanger isoform in the avian colon and is stimulated by mineralocorticoids (1997) (0)
- Mo1756 Phospholipase D Isoforms 1 and 2 Are Required for Carbachol Inhibition of NHE3 in CaCO-2/BBe Cells (2014) (0)
- Mo1793 CK2 Phosphorylatoin of NHE3 At S719 Is Necessary for the PI3-K/AKT Component of Basal NHE3 Activity and for Carbachol/Ca2+ but Not cAMP Inhibition-Effects Involving the Lipid Raft Pool of NHE3 (2013) (0)
- SRC Dynamic Increase in Direct Binding to the PLC-γ SH2 Domain(S), but Not NHE3, is Necessary to Form Signaling Complexes to Allow Carbachol Mediated Inhibition of NHE3 Activity in CACO-2/Bbe Cells (2011) (0)
- Ca sup 2+ channel blockers interact with. alpha. sub 2 -adrenergic receptors in rabbit ileum (1988) (0)
- NA+/H+-exchanger 3 (NHE3) is present in lipid rafts in the ileal absorptive cell brush border: A role for rafts and the actin cytoskeleton in endocytosis of NHE3 (2000) (0)
- The clinicopathologic spectrum of ischemic colitis: Prognostic implications of an evidence-based comprehensive classification (2000) (0)
- 788 - Cholera Toxin (CTX)/Forskolin (FSK) Stimulate Dra (SLC26A3) Related HCO3 Secretion which Involves Apical Trafficking of Dra in Ileal and Proximal Colonic Enteroid Monolayers and CACO-2 Cells (2018) (0)
- Intact jejunal absorption of a synthetic nonapeptide renin inhibitor (1984) (0)
- Mo1121: ADIPOKINE C1Q/TNF-RELATED PROTEIN 3 (CTRP3) SUPPRESSES COLONIC INFLAMMATION IN MOUSE COLITIS MODELS (2022) (0)
- Erratum: (Journal of Physiology (2005) (5-6)) (2005) (0)
- Protein-protein interactions and signalling complexes in regulation of the brush border Na/H antiporter, NHE3 (2014) (0)
- ADF/COF Have Different Effects on Intestinal Brush Border Structure and NHE3 Activity (2015) (0)
- Effects of calcium antagonist 3 4 5 trimethoxybenzoate 8 n n diethylaminooctyl ester on active sodium and chloride transport in rabbit ileum (1986) (0)
- EGF stimulation of ileal naCl absorption requires SRC family kinase activation of brush border (BB) PI 3-kinase (1998) (0)
- Sa1089 SLC26A3 (DRA) IS STIMULATED BY BOTH CAMP AND CA2+ SIGNALING AND THE EFFECT IS SYNERGISTIC IN INTESTINAL EPITHELIAL CELLS BY A PROCESS THAT REQUIRES IRBIT. (2020) (0)
- Faculty Opinions recommendation of Shank2 associates with and regulates Na+/H+ exchanger 3. (2006) (0)
- NHE3 Contains Two Cytoskeleton Associated C-Terminal, Ezrin Containing Signaling Complexes, One for Acute Stimulation and One for Inhibition, Which Together Account for Acute NHE3 Regulation (2011) (0)
- The Zinc Transporter ZIP8 is Induced by Inflammatory Stimuli on the Apical Membrane of Intestinal Epithelial Cells: Potential Role in Interactions with the Microbiota in Crohn's Disease (2017) (0)
- Carbachol-mediated inhibition of Na/H exchanger 3 (NHE3) in ileal brush border (BB) occurs through regulated trafficking and complex formation and involves multiple pools of NHE3 (2003) (0)
- Author response: Duodenum Intestine-Chip for preclinical drug assessment in a human relevant model (2019) (0)
- 882 D-Glucose/SGLT1 Stimulates NHE3 Activity in Intact Mouse Jejunum, a Contributor to the Effect of Ors, By An AKT Dependent Process (2009) (0)
- Regulation of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) by the Nuclear Bile Acid Receptor, Farnesoid X Receptor (2022) (0)
- Epithelial Biology and Secretion Both NHERF3 and NHERF2 are necessary for multiple aspects of acute regulation of NHE3 by elevated Ca 2 (cid:2) , cGMP, and lysophosphatidic acid (2018) (0)
- Epithelial WNT Ligands Ar e Essential Drivers of Intestinal Stem Cell Activation Graphical (2018) (0)
- Oral Sessions (2014) (0)
- Actin turnover is linked to Shiga toxin 1 transcellular transcytosis across intestinal epithelial cells (2007) (0)
- Regulation of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) by the Nuclear Bile Acid Receptor, Farnesoid X Receptor (2020) (0)
- Royal Academy of Medicine in Ireland section of surgery (1994) (0)
- Mo1747 NHERF2/NHERF3 Hetero-Dimerization Is Required for Carbachol Inhibition of NHE3 Activity That Involves Formation of NHE3 Macro-Complexes (2014) (0)
- The utility of endoscopy in the management of acute ischemic colitis (2001) (0)
- 1129: MORANGE2, A GENETICALLY ENCODED, PH SENSITIVE FLUORESCENT PROTEIN, IS AN ALTERNATIVE TO BCECF-AM TO MEASURE INTRACELLULAR PH TO DETERMNE NHE3 AND DRA ACTIVITY (2022) (0)
- Rotavirus Infection Induces LGR5 Intestinal Stem Cell Population via WNT Pathway Stimulation (2017) (0)
- Faculty Opinions recommendation of Epithelial myosin light chain kinase-dependent barrier dysfunction mediates T cell activation-induced diarrhea in vivo. (2005) (0)
- Significance ofAbnormal Rabbit Ileal Histology inthe Pathogenesis ofDiarrhea (1979) (0)
- Calcium/Calmodulin Dependent Protein Kinase II Constitutively Binds, Phosphorylates, and Regulates the Ileal BB Na+/H+ Exchanger NHE3 ; NHE3 IS A NOVEL MEMBER OF THE CaM KINASE II BINDING PROTEINS (2006) (0)
- 521 LONG-LASTING INFLAMMATION IN PATIENTS WITH ULCERATIVE COLITIS CAUSES PERMANENT CHANGES IN GOBLET CELL FUNCTION (2021) (0)
- Effect of spironolactone (S) on mineralocorticoid and glucocorticoid-induced increases in colonic NA and water absorption (1977) (0)
- 401 Human Ex Vivo Enteroid Culture As a Functional Model of Human Small Intestinal Physiology and Pathophysiology: Inhibition of Na+ Absorption by cAMP and Rotavirus and Stimulation of Cl− Secretion by cAMP (2013) (0)
- Fr143 SLC26A3 (DRA) STIMULATES CAMP MEDIATED FLUID SECRETION IN F508DEL-CFTR ORGANOIDS: AN EFFECT ON CFTR AND DRA EXPRESSING ENTEROCYTES. (2021) (0)
- Issue Information (2001) (0)
- Issue Information (2001) (0)
- Mechanisms of Intestinal Electrolyte Transport and Regulation by Calcium (1984) (0)
- From meetings (1988) (0)
- Su1012 – Mechanical Stimuli Affect Enterotoxigenic E. Coli (ETEC) Heat Stable Enterotoxin (ST)-Cyclic Nucleotide Signaling by Altering Mrp4 Expression in a Human Enteroid Monolayer Model of Etec Diarrhea (2019) (0)
- Immunolocalization of ion transport proteins in the gills of teleost fishes (1999) (0)
- M1723 Basal Activity of the Epithelial Brush Border Na/H Exchanger NHE3 Is Stimulated By Both PI-3K and AKT-Dependent and Independent Pathways (2008) (0)
- Cyclic GMP-dependent protein kinase regulation of epithelial transporters (2003) (0)
- Su1844 NHERF2 Contains a Phosphorylatable Ezrin Binding Regulatory Domain, a Newly Identified Motif (2015) (0)
- Actin depolymerizing factor but not cofilin‐1 is necessary to have a normal intestinal brush border (1109.16) (2014) (0)
- Refractory Lymphocytic Enterocolitis and Tumor Necrosis Factor Antagonist Therapy: 258 (2008) (0)
- Prevention and reversal of cholera toxin induced intestinal secretion by methyl prednisolone (MP) (1976) (0)
- Tu1401 Differential Intracellular Calcium Inhibition of NHE3 Activity (2015) (0)
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