Mark Gordon Swain
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Biology
Mark Gordon Swain's Degrees
- PhD Immunology Stanford University
- Bachelors Biology University of California, Berkeley
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(Suggest an Edit or Addition)Mark Gordon Swain's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Cerebral Microglia Recruit Monocytes into the Brain in Response to Tumor Necrosis Factorα Signaling during Peripheral Organ Inflammation (2009) (552)
- Fatigue in chronic disease. (2000) (366)
- A sustained virologic response is durable in patients with chronic hepatitis C treated with peginterferon alfa-2a and ribavirin. (2010) (358)
- Effects of Naloxone Infusions in Patients with the Pruritus of Cholestasis: A Double-Blind, Randomized, Controlled Trial (1995) (333)
- A pilot study of ribavirin therapy for chronic hepatitis C (1992) (300)
- Inducible nitric oxide synthase plays a critical role in resolving intestinal inflammation. (1997) (271)
- Ribavirin as Therapy for Chronic Hepatitis C (1995) (263)
- Environmental stress-induced gastrointestinal permeability is mediated by endogenous glucocorticoids in the rat. (2000) (249)
- Essential Role for Neutrophil Recruitment to the Liver in Concanavalin A-Induced Hepatitis 1 (2004) (197)
- Ribavirin as therapy for chronic hepatitis C. A randomized, double-blind, placebo-controlled trial. (1995) (175)
- Endogenous opioids accumulate in plasma in a rat model of acute cholestasis. (1992) (165)
- Rules of recruitment for Th1 and Th2 lymphocytes in inflamed liver: a role for alpha-4 integrin and vascular adhesion protein-1. (2005) (164)
- Tumor necrosis factor mediation of NSAID-induced gastric damage: role of leukocyte adherence. (1996) (163)
- Increased levels of substance P in the myenteric plexus of Trichinella-infected rats. (1992) (138)
- Immune-to-Brain Communication Pathways in Inflammation-Associated Sickness and Depression. (2017) (134)
- Probiotics Improve Inflammation-Associated Sickness Behavior by Altering Communication between the Peripheral Immune System and the Brain (2015) (134)
- Rituximab for the treatment of patients with autoimmune hepatitis who are refractory or intolerant to standard therapy. (2013) (133)
- Central mu-opioid receptors are down-regulated in a rat model of cholestasis. (1992) (126)
- Impaired sympathetic nerve function in the inflamed rat intestine. (1991) (121)
- Epidemiology and natural history of primary biliary cirrhosis in a Canadian health region: A population‐based study (2009) (121)
- Depression increases the risk of inflammatory bowel disease, which may be mitigated by the use of antidepressants in the treatment of depression (2018) (120)
- Open‐label trial of oral nalmefene therapy for the pruritus of cholestasis (1998) (119)
- The prevalence and incidence of NAFLD worldwide: a systematic review and meta-analysis. (2022) (117)
- Fatigue in liver disease: pathophysiology and clinical management. (2006) (104)
- Seladelpar (MBX-8025), a selective PPAR-δ agonist, in patients with primary biliary cholangitis with an inadequate response to ursodeoxycholic acid: a double-blind, randomised, placebo-controlled, phase 2, proof-of-concept study. (2017) (104)
- Role of chemokines and chemokine receptors in the gastrointestinal tract (2002) (103)
- Mycophenolate mofetil for the treatment of autoimmune hepatitis in patients refractory to standard therapy. (2004) (100)
- Suppression of hypothalamic-pituitary-adrenal axis responsiveness to stress in a rat model of acute cholestasis. (1993) (100)
- Liver Stiffness by Transient Elastography Predicts Liver-Related Complications and Mortality in Patients with Chronic Liver Disease (2014) (98)
- Natural killer T cells regulate the homing of chemokine CXC receptor 3‐positive regulatory T cells to the liver in mice (2009) (97)
- Improvement in cholestasis‐associated fatigue with a serotonin receptor agonist using a novel rat model of fatigue assessment (1997) (97)
- Liver–brain interactions in inflammatory liver diseases: Implications for fatigue and mood disorders (2014) (96)
- B-Cell Depletion With Rituximab in Patients With Primary Biliary Cirrhosis Refractory to Ursodeoxycholic Acid (2013) (95)
- Effect of Inflammation of Enteric Nerves Cytokine‐Induced Changes in Neurotransmitter Content and Release a (1992) (93)
- Successful treatment of refractory type 1 autoimmune hepatitis with methotrexate. (1998) (92)
- CCL3/MIP‐1α is pro‐inflammatory in murine T cell‐mediated hepatitis by recruiting CCR1‐expressing CD4+ T cells to the liver (2004) (91)
- Liver abnormalities in celiac disease. (2004) (91)
- Hepatic NKT cells: friend or foe? (2008) (89)
- A phase 2 study to evaluate the antiviral activity, safety, and pharmacokinetics of recombinant human albumin-interferon alfa fusion protein in genotype 1 chronic hepatitis C patients. (2006) (87)
- Liver-brain inflammation axis. (2011) (87)
- TNF‐α–secreting monocytes are recruited into the brain of cholestatic mice (2006) (85)
- CCR5 deficiency drives enhanced natural killer cell trafficking to and activation within the liver in murine T cell-mediated hepatitis. (2007) (84)
- Defective corticotropin‐releasing hormone mediated neuroendocrine and behavioral responses in cholestatic rats: Implications for cholestatic liver disease–related sickness behaviors (1995) (80)
- Lack of Chemokine Receptor CCR5 Promotes Murine Fulminant Liver Failure by Preventing the Apoptosis of Activated CD1d-Restricted NKT Cells1 (2005) (80)
- Progressive development of a Th1‐type hepatic cytokine profile in rats with experimental cholangitis (2000) (79)
- C-C Chemokine Ligand 2/Monocyte Chemoattractant Protein-1 Directly Inhibits NKT Cell IL-4 Production and Is Hepatoprotective in T Cell-Mediated Hepatitis in the Mouse1 (2003) (72)
- A randomized, controlled trial of recombinant alpha-interferon therapy for chronic hepatitis B. (1993) (71)
- The challenges of primary biliary cholangitis: What is new and what needs to be done. (2019) (68)
- Global Incidence of Acute Pancreatitis is Increasing Over Time: A Systematic Review and Meta-Analysis. (2021) (66)
- Role of NKT cells in autoimmune liver disease. (2011) (66)
- Depression Is Associated with an Increased Risk of Psoriatic Arthritis among Patients with Psoriasis: A Population-Based Study. (2017) (63)
- A randomized, controlled crossover trial of ondansetron in patients with primary biliary cirrhosis and fatigue (2005) (62)
- P-Selectin-Mediated Monocyte–Cerebral Endothelium Adhesive Interactions Link Peripheral Organ Inflammation To Sickness Behaviors (2013) (60)
- Open-label trial of oral nalmefene therapy for the pruritus of cholestasis. (1998) (57)
- Hepatic mucosal mast cell hyperplasia in rats with secondary biliary cirrhosis (1996) (56)
- The global NAFLD policy review and preparedness index: Are countries ready to address this silent public health challenge? (2021) (56)
- Protective role of interleukin-17 in murine NKT cell-driven acute experimental hepatitis. (2010) (56)
- CCR5 in T Cell-Mediated Liver Diseases: What’s Going On?1 (2006) (55)
- Hepatic concentrations of proenkephalin-derived opioids are increased in a rat model of cholestasis. (2008) (55)
- TNF-alpha-secreting monocytes are recruited into the brain of cholestatic mice. (2006) (54)
- Fatigue in chronic liver disease: New insights and therapeutic approaches (2018) (53)
- Chemokines as novel therapeutic targets in inflammatory diseases. (2002) (52)
- A Canadian multicenter retrospective study evaluating transjugular liver biopsy in patients with congenital bleeding disorders and hepatitis C: Is it safe and useful? (2005) (51)
- Increased sensitivity to the locomotor-activating effects of corticotropin-releasing hormone in cholestatic rats. (2002) (48)
- Peginterferon alpha-2a (40kD) [Pegasys] improves HR-QOL outcomes compared with unmodified interferon alpha-2a [Roferon-A]: in patients with chronic hepatitis C. (2003) (48)
- The feasibility and reliability of transient elastography using Fibroscan®: a practice audit of 2335 examinations. (2014) (48)
- Endogenous opioid-mediated antinociception in cholestatic mice is peripherally, not centrally, mediated. (2006) (47)
- Chronic cholestasis in rats induces anhedonia and a loss of social interest (1998) (46)
- Augmented interleukin‐1β–induced depression of locomotor activity in cholestatic rats (1998) (46)
- A Simple Ultrasound Score for the Accurate Detection of Inflammatory Activity in Crohn's Disease (2017) (44)
- Natural Killer T Cells within the Liver: Conductors of the Hepatic Immune Orchestra (2010) (42)
- Therapy of chronic hepatitis B with a 6-month course of ribavirin. (1994) (42)
- Nationwide estimates and risk factors of hospital readmission in patients with cirrhosis in the United States (2019) (40)
- Reversible sclerosing cholangitis secondary to cryptosporidiosis in a renal transplant patient. (2003) (40)
- Depression as a risk factor for the development of rheumatoid arthritis: a population-based cohort study (2018) (38)
- Altered Brain Excitability and Increased Anxiety in Mice With Experimental Colitis: Consideration of Hyperalgesia and Sex Differences (2018) (38)
- Incidence of Appendicitis over Time: A Comparative Analysis of an Administrative Healthcare Database and a Pathology-Proven Appendicitis Registry (2016) (38)
- Efficacy of rituximab in difficult-to-manage autoimmune hepatitis: Results from the International Autoimmune Hepatitis Group (2019) (37)
- Dietary Patterns and Components in Nonalcoholic Fatty Liver Disease (NAFLD): What Key Messages Can Health Care Providers Offer? (2019) (35)
- CD154–CD40 interactions drive hepatocyte apoptosis in murine fulminant hepatitis (2005) (35)
- I. Stress and hepatic inflammation. (2000) (33)
- Population‐based analysis of practices and costs of surveillance for colonic dysplasia in patients with primary sclerosing cholangitis and colitis (2007) (32)
- A case of coexisting primary biliary cirrhosis and primary sclerosing cholangitis: a new overlap of autoimmune liver diseases. (2001) (31)
- Mouse mammary tumor virus in anti-mitochondrial antibody producing mouse models. (2011) (31)
- Neutrophil adhesion is impaired in rat model of cholestasis. (1995) (31)
- Tenofovir disoproxil fumarate significantly decreases serum lipoprotein levels compared with entecavir nucleos(t)ide analogue therapy in chronic hepatitis B carriers (2017) (30)
- Increased midbrain 5-HT1A receptor number and responsiveness in cholestatic rats (2001) (30)
- Adrenal secretion of BAM-22P, a potent opioid peptide, is enhanced in rats with acute cholestasis. (1994) (29)
- Tumor necrosis factor-alpha stimulates adrenal glucocorticoid secretion in cholestatic rats. (1996) (29)
- Burden of nonalcoholic fatty liver disease in Canada, 2019-2030: a modelling study. (2020) (29)
- Regulatory T cells suppress sickness behaviour development without altering liver injury in cholestatic mice. (2012) (28)
- Profound suppression of chronic hepatitis C following superinfection with hepatitis B virus (2007) (27)
- Methotrexate therapy for the symptomatic treatment of primary biliary cirrhosis patients, who are biochemical incomplete responders to ursodeoxycholic acid therapy (2006) (27)
- Prevention of immune-mediated arthritis in cholestatic rats: involvement of endogenous glucocorticoids. (1994) (27)
- Peginterferon α-2a (40kD) [Pegasys®] Improves HR-QOL Outcomes Compared with Unmodified Interferon α-2a [Roferon®-A] (2012) (27)
- Endogenous glucocorticoids inhibit neutrophil recruitment to inflammatory sites in cholestatic rats. (1996) (26)
- Ledipasvir-Sofosbuvir Plus Ribavirin in Treatment-Naive Patients With Hepatitis C Virus Genotype 3 Infection: An Open-Label Study (2017) (26)
- Familial idiopathic adulthood ductopenia: a report of five cases in three generations. (2000) (26)
- The burden of hepatitis B virus (HBV) infection, genotypes and drug resistance mutations in human immunodeficiency virus-positive patients in Northwest Ethiopia (2017) (26)
- Endogenous glucocorticoids released during acute toxic liver injury enhance hepatic IL-10 synthesis and release. (1999) (26)
- Role of Peripheral Inflammation in Hepatic Encephalopathy. (2018) (25)
- TNFα Augments Cytokine-Induced NK Cell IFNγ Production through TNFR2 (2016) (25)
- Interactions Between Platelets and Inflammatory Monocytes Affect Sickness Behavior in Mice With Liver Inflammation. (2017) (24)
- Safety and antiviral activity of albinterferon alfa-2b dosed every four weeks in genotype 2/3 chronic hepatitis C patients. (2008) (23)
- Reactivation of hepatitis B e antigen-negative chronic hepatitis B in a bone marrow transplant recipient following lamivudine withdrawal. (2001) (23)
- Downregulated hypothalamic 5‐HT3 receptor expression and enhanced 5‐HT3 receptor antagonist‐mediated improvement in fatigue‐like behaviour in cholestatic rats (2008) (22)
- Real‐World Effectiveness of Obeticholic Acid in Patients with Primary Biliary Cholangitis (2020) (22)
- Primary biliary cirrhosis: Report of a focus study group (2004) (22)
- [1] DURABLE SUSTAINED VIROLOGICAL RESPONSE AFTER TREATMENT WITH PEGINTERFERON α-2a (PEGASYS®) ALONE OR IN COMBINATION WITH RlBAVlRlN (COPEGUS®): 5-YEAR FOLLOW-UP AND THE CRITERIA OF A CURE (2007) (22)
- Primary Biliary Cholangitis Alters Functional Connections of the Brain’s Deep Gray Matter (2017) (22)
- CASE REPORT: A Case of Coexisting Primary Biliary Cirrhosis and Primary Sclerosing Cholangitis: A New Overlap of Autoimmune Liver Diseases (2001) (20)
- Validation of coding algorithms for the identification of patients with primary biliary cirrhosis using administrative data. (2010) (20)
- Defective interleukin-1-induced ACTH release in cholestatic rats: impaired hypothalamic PGE2 release. (1995) (20)
- Validation of coding algorithms for the identification of patients hospitalized for alcoholic hepatitis using administrative data (2015) (20)
- Hypothalamic nitric oxide synthase is depressed in cholestatic rats. (1997) (20)
- Evaluation of classical and novel autoantibodies for the diagnosis of Primary Biliary Cholangitis-Autoimmune Hepatitis Overlap Syndrome (PBC-AIH OS) (2018) (19)
- Hepatitis C in Patients With Minimal or No Hepatic Fibrosis: The Impact of Treatment and Sustained Virologic Response on Patient-Reported Outcomes (2018) (19)
- Ulcerative colitis-associated hospitalization costs: a population-based study. (2015) (18)
- Blood‐brain barrier permeability is markedly decreased in cholestasis in the rat (1993) (18)
- The impact of depression and antidepressant usage on primary biliary cholangitis clinical outcomes (2018) (18)
- Predicting efficacy and safety outcomes in patients with hepatitis C virus genotype 1 and persistently ‘normal’ alanine aminotransferase levels treated with peginterferon α‐2a (40KD) plus ribavirin (2007) (17)
- The Prevalence of Anti-Hexokinase-1 and Anti-Kelch-Like 12 Peptide Antibodies in Patients With Primary Biliary Cholangitis Is Similar in Europe and North America: A Large International, Multi-Center Study (2019) (17)
- Impact of the COVID-19 Pandemic on Hospitalizations for Alcoholic Hepatitis or Cirrhosis in Alberta, Canada (2021) (17)
- Rapid activation and hepatic recruitment of innate-like regulatory B cells after invariant NKT cell stimulation in mice. (2015) (16)
- Role of methotrexate in the treatment of chronic cholestatic disorders. (2008) (16)
- Experimental Colitis Attenuates Development of Toxin-Induced Cholangitis in Rats (2002) (16)
- The Antidepressant Mirtazapine Inhibits Hepatic Innate Immune Networks to Attenuate Immune-Mediated Liver Injury in Mice (2019) (16)
- Stress and the gastrointestinal tract. I. Stress and hepatic inflammation (2000) (15)
- Increased opioid binding to peripheral white blood cells in a rat model of acute cholestasis. (1995) (15)
- Anti-TNF-induced autoimmune hepatitis. (2014) (15)
- TNF-α facilitates inflammation-induced glucocorticoid secretion in rats with biliary obstruction (1997) (14)
- Endogenous glucocorticoids released during acute toxic liver injury enhance hepatic IL-10 synthesis and release. (1999) (14)
- Gastrin-releasing peptide and pruritus: more than just scratching the surface. (2008) (14)
- Decreased orexigenic response to neuropeptide Y in rats with obstructive cholestasis. (2001) (14)
- Attenuated febrile response to lipopolysaccharide in rats with biliary obstruction. (2000) (14)
- Risk factors for mortality in patients with alcoholic hepatitis and assessment of prognostic models: A population-based study. (2015) (13)
- Cytokines and neuroendocrine dysregulation in obstructive cholestasis: pathophysiological implications. (2001) (13)
- Magnetic resonance imaging evidence of hippocampal structural changes in patients with primary biliary cholangitis (2018) (13)
- Blood cytokine, chemokine and gene expression in cholestasis patients with intractable pruritis treated with a molecular adsorbent recirculating system: a case series. (2012) (13)
- Inhibition of uroporphyrinogen decarboxylase by 3,3',4,4'-tetrachlorobiphenyl in chick embryo liver cell culture. (1983) (13)
- Peripartum cytokine flares in a multiethnic cohort of chronic hepatitis B carriers does not correlate with hepatitis B virus suppression or increased risk of liver disease (2017) (12)
- Real‐world clinical and virological outcomes in a retrospective multiethnic cohort study of 341 untreated and tenofovir disoproxil fumarate‐treated chronic hepatitis B pregnant patients in North America (2020) (12)
- Effects of the neutral endopeptidase inhibitor thiorphan on cardiovascular and renal function in cirrhotic rats (2003) (12)
- Risk stratification of patients with nonalcoholic fatty liver disease using a case identification pathway in primary care: a cross-sectional study. (2020) (12)
- Glucocorticoid receptors are downregulated in hepatic T lymphocytes in rats with experimental cholangitis (2003) (12)
- Impaired neutrophil microbicidal activity in rat cholestasis. (1997) (12)
- GS-02-Efficacy of GKT831 in patients with primary biliary cholangitis and inadequate response to ursodeoxycholic acid: Interim efficacy results of a phase 2 clinical trial (2019) (11)
- Validation of the Model of End-Stage Liver Disease for Liver Transplant Allocation in Alberta: Implications for Future Directions in Canada (2016) (11)
- Modelling the cost effectiveness of non-alcoholic fatty liver disease risk stratification strategies in the community setting (2021) (11)
- Sympathetic nerves, but not the adrenal gland, contribute to elevated plasma levels of met-enkephalin in rats with acute cholestatic hepatitis (1993) (10)
- Time to make the change from 'primary biliary cirrhosis' to 'primary biliary cholangitis'. (2015) (10)
- Alterations in hypothalamic μ‐opiate receptor—mediated responses but not methionine enkephalin or proenkephalin messenger RNA levels in rats with acute cholestasis (1994) (10)
- Dynamics of interferon-specific gene expression in peripheral blood of interferon alfa-naïve patients with genotype 1 chronic hepatitis C infection treated with albumin-interferon alfa. (2006) (9)
- Impaired stress and interleukin‐1β‐induced hypothalamic expression of the neuronal activation marker FOS in cholestatic rats (1996) (9)
- Acceptability and yield of birth-cohort screening for hepatitis C virus in a Canadian population being screened for colorectal cancer: a cross-sectional study. (2015) (9)
- Plasma endopeptidase 24.11 (enkephalinase) activity is markedly increased in cholestatic liver disease (1993) (9)
- Fatigue in cirrhosis: is transplant the answer? (2012) (9)
- Brain TNF drives post-inflammation depression-like behavior and persistent pain in experimental arthritis (2020) (9)
- End-stage liver disease developing with the use of methotrexate in heterozygous alpha 1-antitrypsin deficiency. (1995) (9)
- Differential leptin responses to acute and chronic biliary obstruction in rats. (2000) (9)
- Neuroinflammation in liver disease: sessional talks from ISHEN (2016) (8)
- Treatment of patients with chronic hepatitis C (CHC) with peginterferon alfa-2a (40KD) (Pegasys) alone or in combination with ribavirin (copegus) results in long-lasting sustained virological response (2003) (8)
- A phase II, randomized, open-label, 52-week study of seladelpar in patients with primary biliary cholangitis. (2022) (8)
- Rituximab treatment experience in patients with complicated type 1 autoimmune hepatitis in Europe and North America (2018) (7)
- Colitis-associated microbiota drives changes in behaviour in male mice in the absence of inflammation (2022) (7)
- Trends in the Economic Burden of Chronic Liver Diseases and Cirrhosis in the United States: 1996–2016 (2021) (7)
- Real-world treatment of hepatitis C with second-generation direct-acting antivirals: initial results from a multicentre Canadian retrospective cohort of diverse patients. (2018) (7)
- Prevalence and risk factors for liver fibrosis detected by transient elastography or shear wave elastography in inflammatory arthritis: a systematic review. (2017) (7)
- Massive intrahepatic hemorrhage following routine liver biopsy in a patient with rheumatoid arthritis treated with methotrexate. (1992) (7)
- Reduced immune responses to hepatitis B primary vaccination in obese individuals with nonalcoholic fatty liver disease (NAFLD) (2021) (7)
- Primary biliary cholangitis patients exhibit MRI changes in structure and function of interoceptive brain regions (2019) (6)
- Durability of treatment response after 1 year of therapy with seladelpar in patients with primary biliary cholangitis (PBC): final results of an international phase 2 study (2020) (6)
- Behavioural adaptations after antibiotic treatment in male mice are reversed by activation of the aryl hydrocarbon receptor (2021) (6)
- Hepatitis B virus testing and linkage to care in a Canadian urban tertiary referral centre: a retrospective cohort study. (2017) (6)
- A case series evaluating the impact of Hepatitis C eradication using direct acting antivirals on primary biliary cholangitis-associated autoimmunity (2018) (5)
- Impact of major depression and antidepressant use on alcoholic and non‐alcoholic fatty liver disease: A population‐based study (2021) (5)
- TNF-alpha facilitates inflammation-induced glucocorticoid secretion in rats with biliary obstruction. (1997) (5)
- Near‐Infrared Spectroscopy Reveals Brain Hypoxia and Cerebrovascular Dysregulation in Primary Biliary Cholangitis (2020) (5)
- Hepatitis C Virus Screening of High-Risk Patients in a Canadian Emergency Department (2020) (5)
- Prevalence and molecular characterization of occult hepatitis B virus in pregnant women from Gondar, Ethiopia. (2020) (5)
- Association between Endoscopist Specialty and Colonoscopy Quality: a Systematic Review and Meta-analysis. (2021) (4)
- A Canadian survey on knowledge of non-alcoholic fatty liver disease among physicians. (2021) (4)
- Treatment efficacy and safety of seladelpar, a selective peroxisome proliferator-activated receptor delta agonist, in primary biliary cholangitis patients: 12- and 26-week analysis from an ongoing international, randomized, dose raging phase 2 study (2018) (4)
- Efficacy and safety of seladelpar, a selective peroxisome proliferator-activated receptor delta agonist, in primary biliary cholangitis: 52-week analysis of an ongoing international, randomized, dose ranging phase 2 study. (2018) (4)
- Current considerations for clinical management and care of non-alcoholic fatty liver disease: Insights from the 1st International Workshop of the Canadian NASH Network (CanNASH) (2021) (4)
- 1287 RITUXIMAB FOR REFRACTORY AUTOIMMUNE HEPATITIS: F RESULTS OF A PHASE 1 STUDY (2011) (4)
- Characteristics and Outcomes of Children With Cystic Fibrosis Hospitalized With Cirrhosis in the United States (2021) (4)
- Methionine enkephalin accumulates in plasma but not in brain or cerebrospinal fluid of rats with acute toxic hepatitis (1992) (3)
- Treatment outcomes with telaprevir-based therapy for HIV/hepatitis C coinfected patients are comparable with hepatitis C monoinfected patients (2015) (3)
- Canadian regulations and legal ramifications for hepatic encephalopathy: a descriptive analysis. (2018) (3)
- Hepatitis C virus treatment complicated by rheumatoid arthritis. (2011) (3)
- Changing epidemiology and natural history of primary biliary cirrhosis (2014) (3)
- Long-Term Follow-up and Quantitative Hepatitis B Surface Antigen Monitoring in North American Chronic HBV Carriers. (2018) (3)
- Long-Term Follow-up and Quantitative Hepatitis B Surface Antigen Monitoring in North American Chronic HBV Carriers. (2018) (3)
- Race and Ethnicity in Non-Alcoholic Fatty Liver Disease (NAFLD): A Narrative Review (2022) (3)
- Ethnicity, disease severity, and survival in Canadian patients with primary biliary cholangitis (2022) (3)
- Chronic lymphocytic leukemia-associated cholangiopathy. (2011) (3)
- [9] COMPARABLE ANTIVIRAL RESPONSE RATES WITH ALBUMIN INTERFERON ALFA-2B DOSED AT Q2W OR Q4W INTERVALS IN NAIVE SUBJECTS WITH GENOTYPE 2 OR 3 CHRONIC HEPATITIS C (2007) (3)
- Mo1107 A Cost-Utility Analysis of Novel and Current Strategies for the Management of Uninvestigated Dyspepsia (2014) (3)
- 611 Poor prognostic factors in heavier patients with chronic hepatitis C (CHC) result in less favourable treatment outcomes (2006) (3)
- Recruitment of α4β7 monocytes and neutrophils to the brain in experimental colitis is associated with elevated cytokines and anxiety-like behavior (2022) (3)
- Do Low-Risk Patients With Dyspepsia Need a Gastroscopy? Use of Gastroscopy for Otherwise Healthy Patients With Dyspepsia (2021) (3)
- The Antidepressant Mirtazapine Rapidly Shifts Hepatic B Cell Populations and Functional Cytokine Signatures in the Mouse (2021) (3)
- Behavioral Comorbidities in Dextran Sulphate Sodium (DSS) Colitis, an animal model of Inflammatory Bowel Diseases (2016) (2)
- Ledipasvir/Sofosbuvir with Ribavirin for 12 Weeks is Effective and Safe in Treatment-Naïve Genotype-3 Hepatitis C-Infected Patients in Canada (2016) (2)
- Fatigue in the primary biliary cirrhosis patient (1998) (2)
- Multimodal Brain MRI of Deep Gray Matter Changes Associated With Inflammatory Bowel Disease. (2022) (2)
- Sa1074 Nurse-Led, Interactive Group Sessions for Dyspepsia and GERD Referrals: A Prospective Controlled Study of the “Nurse Navigator” Clinic (2014) (2)
- Letter to Editor: Using Proper Methods to Identify Patients With Cirrhosis in Administrative Databases Is Crucial to Correctly Predict Outcomes (2019) (2)
- The Antidepressant Mirtazapine Activates Hepatic Macrophages, Facilitating Pathogen Clearance While Limiting Tissue Damage in Mice (2020) (2)
- A183 SOFOSBUVIR-BASED ALL-ORAL REGIMENS FOR PATIENTS WITH CHRONIC HEPATITIS C GENOTYPE 3 INFECTION: INTEGRATED ANALYSIS OF FIVE CLINICAL STUDIES (2018) (1)
- Efficacy of a Peruvian Botanical Remedy (Sabell A4+) for Treating Liver Disease and Protecting Gastric Mucosal Integrity (2019) (1)
- Induction versus noninduction antiviral therapy for chronic hepatitis C virus in patients with congenital coagulation disorders: a Canadian multicentre trial. (2007) (1)
- A Review on Biomarkers for the Evaluation of Autoimmune Cholestatic Liver Diseases and Their Overlap Syndromes (2022) (1)
- Dynamics of Serum Quantitative Hepatitis B Surface Antigen Testing in Assessing Nucleos/Tide Analog Treatment Response and Disease Phenotype in Chronic Hepatitis B Patients in Canada (2016) (1)
- Validation, current use and future directions of the Model for End-stage Liver Disease for liver transplant allocation in Canada. (2015) (1)
- A230 NOT ALL PATIENTS WITH GASTROINTESTINAL COMPLAINTS REQUIRE SPECIALIST CARE: TWO YEAR OUTCOMES FROM AN ENHANCED PRIMARY CARE PATHWAY (2018) (1)
- Evaluating the role of transient elastography post chronic hepatitis C treatment to predict hepatocellular carcinoma. (2020) (1)
- A22 ROUTINE GASTROINTESTINAL REFERRAL WAIT LIST REDUCTION VIA AN ENHANCED PRIMARY CARE PATHWAY (2019) (1)
- Editorial: choosing an appropriate risk stratification tool for nonalcoholic fatty liver disease—one size does not fit all (2020) (1)
- SAT-325-Implementation of a primary care shear-wave elastography-based pathway to identify non-alcoholic fatty liver disease patients with advanced fibrosis in a large North American urban population (2019) (1)
- A78 DIRECT-ACTING ANTIVIRALS ARE NOT ASSOCIATED WITH EARLY TUMOR RECURRENCE AFTER CURATIVE TREATMENTS IN HEPATITIS C-RELATED HEPATOCELLULAR CARCINOMA (2018) (1)
- Impact of setanaxib on quality of life outcomes in primary biliary cholangitis in a phase 2 randomized controlled trial (2023) (1)
- Neuroimaging Evidence of Hippocampal Changes in Primary Biliary Cirrhosis Consistent with Tissue Injury or Stres (2016) (1)
- Nurse-Led, Shared Medical Appointments for Common Gastrointestinal Conditions—Improving Outcomes Through Collaboration With Primary Care in the Medical Home: A Prospective Observational Study (2018) (1)
- Tu1954 Colonic Confocal Laser Endomicroscopy Findings in Patients With Primary Sclerosing Cholangitis (2013) (1)
- FRI-056-Obeticholic acid as adjunctive therapy in Primary Biliary Cholangitis: A review of early real-world experience (2019) (1)
- Proof of efficacy for Seladelpar, a selective PPAR-δ agonist, in patients with primary biliary cholangitis non-responsive to ursodeoxycholic acid: results of an international Phase 2 randomised controlled clinical study (2017) (1)
- Direct-Acting Antivirals Are not Associated With Early Tumor Recurrence After Curative Treatments in Hepatitis C-related Hepatocellular Carcinoma: 930 (2017) (1)
- INCIDENCE AND PREVALENCE OF PRIMARY SCLEROSING CHOLANGITIS: A META-ANALYSIS OF POPULATION-BASED STUDIES (2022) (1)
- Proceedings from the 2018 Canadian Association for the Study of the Liver Single Topic Conference-Decompensated cirrhosis: from clinic to transplant. (2019) (0)
- Performance of non-invasive fibrosis tests among non-alcoholic fatty liver disease (NAFLD) patients with normal alanine aminotransferase (ALT): data from a large North American primary care NAFLD pathway (2020) (0)
- A202 IMPACT OF THE COVID-19 PANDEMIC ON THE EPIDEMIOLOGY OF ALCOHOL-RELATED HEPATITIS (2022) (0)
- Targeted Temperature Management as a Cause of Liver Injury (2019) (0)
- A44 A 1000 PATIENT CANADIAN NETWORK FOR AUTOIMMUNE LIVER DISEASE EVALUATION OF CLINICAL AND DEMOGRAPHIC PATTERNS OF AUTOIMMUNE HEPATITIS (2023) (0)
- Characteristics and outcomes of cystic fibrosis paediatric patients admitted with cirrhosis in the United States (2018) (0)
- Letter: lipid‐lowering effect of tenofovir disoproxil fumarate in chronic hepatitis B—more evidence is needed. Authors’ reply (2017) (0)
- P351 TNFα CLEAVING ENZYME (TACE/ADAM 17) IS AN IMPORTANT DRIVER OF CHOLESTASIS-ASSOCIATED LIVER INJURY AND SICKNESS BEHAVIOR DEVELOPMENT (2014) (0)
- Quality of life outcomes in patients with primary biliary cholangitis treated with setanaxib: post-hoc results from a phase 2 randomised, placebo-controlled trial (2022) (0)
- Mo1284 – Comparing Outcomes in Upper Gastrointestinal Bleeding for Patients Living Within Vs Outside Large Urban Centres: A Population-Based Cohort Study (2019) (0)
- CHOLESTATIC LIVER DISEASE AND BRAIN DYSFUNCTION: ROLE OF THE ARYL HYDROCARBON RECEPTOR (2020) (0)
- Recruitment of α4β7 monocytes and neutrophils to the brain in experimental colitis is associated with elevated cytokines and anxiety-like behavior (2022) (0)
- Antigen‐Induced Arthritis Leads to Depression‐Like Behavior in Mice Mediated by Central TNFα (2019) (0)
- A231 URGENT PRIORITY ENDOSCOPY PATHWAY IN A HIGH VOLUME CENTRAL ACCESS MODEL: OPTIMIZING GASTROENTEROLGY CARE FOR THE SICKEST PATIENTS (2018) (0)
- Pruritus in Primary Sclerosing Cholangitis: New Insights into Cause and Treatment (2017) (0)
- P368 COGNITIVE AND EMOTIONAL PROCESSING NETWORKS ARE IMPACTED BY SENSORY INPUT TO THE THALAMUS IN PATIENTS WITH PRIMARY BILIARY CIRRHOSIS (2014) (0)
- The prevalence of primary biliary cholangitis (PBC) is on the rise: a canadian population-based study (2022) (0)
- A194 CAN NOVEL SEROLOGICAL MARKERS BE USED TO BETTER DEFINE PRIMARY BILIARY CHOLANGITIS (PBC)-AUTOIMMUNE HEPATITIS (AIH) OVERLAP SYNDROME (2018) (0)
- Hepatitis the Liver in Concanavalin A-Induced Essential Role for Neutrophil Recruitment to (2003) (0)
- Development of a multivariate model using serum biomarkers to better define primary biliary cholangitis (PBC)-autoimmune hepatitis (AIH) overlap syndrome (2017) (0)
- Reduced immune responses to hepatitis B primary vaccination in obese individuals with nonalcoholic fatty liver disease (NAFLD) (2021) (0)
- Mo1931 – Urine Metabolomic Signatures Differentiate Pregnancy from the Non-Pregnant State and Differ in Pregnant Patients with Crohn’s Disease Compared with Ulcerative Colitis (2019) (0)
- Tu1261: IMPACT OF THE COVID-19 PANDEMIC ON THE EPIDEMIOLOGY OF ALCOHOL-ASSOCIATED HEPATITIS (2022) (0)
- Impact of depression and antidepressant use on clinical outcomes of hepatitis B and C: a population-based study (2023) (0)
- Downregulation of hepatic T cell glucocorticoid receptors nn rats with exprimental cholangitis (2001) (0)
- A187 CHOLESTATIC LIVER DISEASE AND BRAIN DYSFUNCTION: ROLE OF THE ARYL HYDROCARBON RECEPTOR (2020) (0)
- A210 DECLINE IN HEPATITIS B QUANTITATIVE SURFACE ANTIGEN LEVELS IN CHRONIC HEPATITIS B PATIENTS ON TREATMENT WITH NUCLEOS(T)IDE ANALOGUES (2021) (0)
- Assessment of baseline Hepatitis B Virus (HBV) immunity and HBV vaccine responses in prospectively vaccinated adults with Non Alcoholic Fatty Liver Disease (NAFLD) (2018) (0)
- University of Birmingham Ulcerative colitis-associated hospitalization costs (2016) (0)
- Substrates for hypothalamic PGE2 synthesis are not decreased in cholestatic rats. (1996) (0)
- Patients with primary biliary cholangitis exhibit reduced hippocampal volume and MRI evidence of neuroinflammation (2018) (0)
- Increased hospital admissions for alcohol-associated hepatitis during the COVID-19 pandemic in Alberta, Canada: a retrospective cohort study (2022) (0)
- Tu1251: INCIDENCE AND PREVALENCE OF PRIMARY SCLEROSING CHOLANGITIS: A META-ANALYSIS OF POPULATION-BASED STUDIES (2022) (0)
- Central presynaptic serotonin 5HT1A autoreceptor responsiveness is enhanced in cholestatic rats (1998) (0)
- A286 MICROBIOTA DEPLETION IN ADULTHOOD ALTERS MOUSE BEHAVIOR WITH POTENTIAL INVOLVEMENT OF MICROBIAL-METABOLITE SENSOR IN THE BRAIN (2018) (0)
- Supplementary Material for: TNFα Augments Cytokine-Induced NK Cell IFNγ Production through TNFR2 (2016) (0)
- Effect of inhibition of ornithine decarboxylase activity in a model of acute hepatocellular necrosis (1998) (0)
- THU-252-Nursing staff volume is the most significant predictor of improved in-hospital mortality among alcoholic hepatitis patients admitted with ascites or hepatic encephalopathy: US nationwide population-based study (2019) (0)
- The antidepressant mirtazapine improves survival in patients with primary biliary cholangitis (2018) (0)
- The atypical antidepressant mirtazapine is hepatoprotective in a mouse model of immune-mediated hepatitis (2018) (0)
- A62 CANADIAN POPULATION-BASED EVALUATION OF THE NATURAL HISTORY OF PRIMARY BILIARY CHOLANGITIS OVER THE LAST DECADE (2020) (0)
- Impact of access to specialized health care on the primary biliary cholangitis (PBC) patient outcomes: a Canadian experience (2018) (0)
- Leukocyte - Cerebral Endothelial Cell Interactions in the Brain Lead to Anxiety-like Behaviour in Experimental Colitis (2021) (0)
- A qualitative patient interview study to understand the experience of patients with nonalcoholic steatohepatitis (2023) (0)
- Reply: (2006) (0)
- Alterations in Brain Structure and functionidentified in Cholestatic Mice Using Manganese-Enhanced Mri Neuroimaging (2016) (0)
- Increased IL-1?:IL-1ra mRNA ratio in adrenal glands of cholestatic rats: Possible mechanism for enhanced adrenal glucocorticoid secretion in cholestasis (1995) (0)
- TNF- (cid:1) –Secreting Monocytes Are Recruited Into the Brain of Cholestatic Mice (2005) (0)
- P378 BENEFICIAL EFFECT OF THE PROBIOTIC VSL-3 ON LIVER INJURY-ASSOCIATED SICKNESS BEHAVIOR DEVELOPMENT BY ALTERING SYSTEMIC IMMUNITY AND INHIBITING ACTIVATED MONOCYTES FROM ENTERING THE BRAIN (2014) (0)
- P273 Colonic confocal laser endomicroscopy findings in patients with primary sclerosing cholangitis (2013) (0)
- Familial idiopathic adulthood bile ductopenia: A report of five cases in three generations (1998) (0)
- The Worldwide Burden of NAFLD: A Systematic Review and Meta-Analysis of Prevalence and Incidence (2022) (0)
- Single Topic Conference on Autoimmune Liver Disease from the Canadian Association for the Study of the Liver (2021) (0)
- Cover (2015) (0)
- Endogenous gluco-corticouds inhibit leukocyte recruitment to inflammatory sites in cholestatic rats (1995) (0)
- Hepatitis in the Mouse Hepatoprotective in T Cell-Mediated NKT Cell IL-4 Production and Is Chemoattractant Protein-1 Directly Inhibits C-C Chemokine Ligand 2 / Monocyte (2003) (0)
- P120: Rapid hepatitis C virus screening and diagnostic testing for high-risk patients in an urban emergency department: a pilot project (2018) (0)
- Altered Cyclosporine Absorption in a Patient with Ulcerative Colitis, Sclerosing Cholangitis and Pancreatic Insufficiency (1991) (0)
- 686 ACTIVATED INVARIANT NKT CELLS RAPIDLY PRODUCE INTERLEUKIN-17 WHICH IS ANTI-INFLAMMATORY IN EXPERIMENTAL HEPATITIS (2009) (0)
- Screening for Dysplasia in Primary Sclerosing Cholangitis – A Population-Based Assessment of Physician Practices: 851 (2005) (0)
- FRI-055-Failure to normalize ALT and IgG in Autoimmune Hepatitis is associated with more advanced liver disease: Perspectives from a multi-ethnic Canadian AIH registry (2019) (0)
- Clinical prediction rule to determine the need for repeat ERCP after endoscopic treatment of postsurgical bile leaks. (2017) (0)
- CD 1 d-Restricted NKT Cells Preventing the Apoptosis of Activated byPromotes Murine Fulminant Liver Failure Lack of Chemokine Receptor CCR 5 (2005) (0)
- PS-175-The burden of alcoholic cirrhosis is critically increasing in Canada: A population-based study (2019) (0)
- 54 ACTIVATED HEPATIC NKT CELLS RECRUIT CXCR3 EXPRESSING REGULATORY T CELLS (T REGS) INTO THE LIVER VIA A CYTOKINE-TO-CHEMOKINE CASCADE (2008) (0)
- The burden of cirrhosis on the Canadian healthcare system: a comparison between alcoholic and non-alcoholic cirrhosis patients (2020) (0)
- 686 EFFECTS ON PRURITUS AND SLEEP DISTURBANCE IN PATIENTS WITH PRIMARY BILIARY CHOLANGITIS (PBC) AFTER 1 YEAR OF TREATMENT WITH SELADELPAR, A PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR DELTA AGONIST: RESULTS OF AN OPEN-LABEL PHASE 2 STUDY (2020) (0)
- Using cc-chemokine CCL5 / RANTES mutant for treatment of liver diseases (2003) (0)
- Cholestatic rats demonstrate locomotor retardation which is mediated by corticotropin releasing hormone via type 2 receptors (2000) (0)
- Antigen‐Induced Arthritis in Mice induces Depression‐Like Behavior and Microglial Activation in Hippocampus after the Resolution of Peripheral Inflammation (2018) (0)
- Tumor Necrosis Factor Alpha (Tnfα) Cleaving Enzyme (TACE/ADAM17) Expression is Enhanced in Cholestatic Liver Disease and Regulates Cholestasis-Associated Liver Injury and Sickness Behavior Development (2017) (0)
- Validation of a novel method of identifying patients with Primary Sclerosing Cholangitis (PSC) in a canadian population (2022) (0)
- A76 CLINICAL OUTCOMES, HEALTHCARE UTILIZATION AND COSTS AVOIDED WHEN ROUTINE GASTROENTEROLOGY REFERRALS ARE MANAGED IN PRIMARY CARE SUPPORTED BY CO-DEVELOPED CLINICAL CARE PATHWAYS (2021) (0)
- 685 PREVENTION OF MONOCYTE RECRUITMENT INTO THE BRAIN PREVENTS FATIGUE-LIKE BEHAVIOURS IN CHOLESTATIC MICE (2009) (0)
- Recurrent Primary Sclerosing Cholangitis After Liver Transplantation (2017) (0)
- A185 IMPACT OF HEPATITIS C ERADICATION USING DIRECT ACTING ANTIVIRALS ON CONCURRENT PRIMARY BILIARY CHOLANGITIS AND ASSOCIATED AUTOIMMUNITY. (2018) (0)
- Case report Reversible sclerosing cholangitis secondary to cryptosporidiosis in a renal transplant patient (2003) (0)
- A202 BIOCHEMICAL PROFILE IN 68 PRIMARY BILIARY CHOLANGITIS (PBC) SUBJECTS HAVING AN INADEQUATE RESPONSE TO URSODEOXYCHOLIC ACID (2018) (0)
- Anti–Valosin‐Containing Protein (VCP/p97) Autoantibodies in Inclusion Body Myositis and Other Inflammatory Myopathies (2022) (0)
- 1111 PERIPHERAL TREG S REGULATE SICKNESS BEHAVIOUR DEVELOPMENT IN INFLAMMATORY LIVER DISEASE (2010) (0)
- Clinical characterization of patients with primary biliary cholangitis: A report from multiple Canadian centres. (2022) (0)
- CD1d-Restricted NKT Cells Preventing the Apoptosis of Activated by Promotes Murine Fulminant Liver Failure Lack of Chemokine Receptor CCR5 (2005) (0)
- Real-world tertiary referral centre experience stopping nucleos(t)ide analogue therapy in patients with chronic hepatitis B (2022) (0)
- A134 ANALYSIS OF POTENTIAL MICROBIAL-METABOLITE SENSORS IN THE BRAIN DURING EXPERIMENTAL COLITIS (2018) (0)
- A new score including anthropometric measurement for weight improved prediction of mortality in adolescents on the liver transplantation waiting list: a US nationwide study (2020) (0)
- Role of pre- and post-treatment transient elastography measurements in predicting hepatocellular carcinoma (HCC) among hepatitis C patients treated with direct acting antivirals (DAAs) (2020) (0)
- A268 A CASE OF SEVERE RIGHT UPPER QUADRANT PAIN SECONDARY TO AN IGG4 RELATED INFLAMMATORY PSEUDOTUMOUR INFILTRATING THE LIVER CAPSULE (2018) (0)
- Leptin does not mediate the anorexia associated with biliary obstruction in rats (1998) (0)
- Pathophysiological Basis of Pruritus and Fatigue in Cholestasis (2004) (0)
- Mycophenolate mofetil for the treatment of autoimmune hepatitis in patients unresponsive to or unable to take azathiroprine or 6-mercaptopurine (2003) (0)
- Seladelpar efficacy and safety at 3 months in patients with primary biliary cholangitis: ENHANCE, a phase 3, randomized, placebo-controlled study (2023) (0)
- TLR4 Activation Drives Systemic Platelet: Monocyte Aggregate Formation and Monocyte TNFA Production and is Critical for the Development of Fatigue-Like Behaviors in Mice with Experimental Cholestatic Liver Disease (2016) (0)
- A211 INCIDENCE OF PRIMARY SCLEROSING CHOLANGITIS: A META-ANALYSIS OF POPULATION-BASED STUDIES (2022) (0)
- The gut–liver–brain axis: dietary and therapeutic interventions (2021) (0)
- A200 AN INTEGRATED ANALYSIS OF EFFICACY OF OBETICHOLIC ACID IN CANADIAN PATIENTS (2018) (0)
- A16 SUCCESS OF ENHANCED PRIMARY CARE PATHWAYS IN MANAGING ROUTINE GI REFERRALS. (2018) (0)
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What Schools Are Affiliated With Mark Gordon Swain?
Mark Gordon Swain is affiliated with the following schools:
