Mark H. Wilcox
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Engineering Computer Science
Mark H. Wilcox's Degrees
- PhD Computer Science Stanford University
- Masters Electrical Engineering University of California, Berkeley
- Bachelors Computer Engineering University of California, Berkeley
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(Suggest an Edit or Addition)Mark H. Wilcox's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Clinical Practice Guidelines for Clostridium difficile Infection in Adults: 2010 Update by the Society for Healthcare Epidemiology of America (SHEA) and the Infectious Diseases Society of America (IDSA) (2010) (2616)
- Clostridium difficile infection: new developments in epidemiology and pathogenesis (2009) (1354)
- Interventions to improve antibiotic prescribing practices for hospital inpatients. (2017) (1218)
- Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA). (2018) (1149)
- Vancomycin-resistant enterococci (1993) (1107)
- Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA). (2018) (1083)
- epic3: National Evidence-Based Guidelines for Preventing Healthcare-Associated Infections in NHS Hospitals in England (2007) (1060)
- The Changing Epidemiology of Clostridium difficile Infections (2010) (817)
- Clostridium difficile infection in Europe: a hospital-based survey (2011) (805)
- Emergence and global spread of epidemic healthcare-associated Clostridium difficile (2012) (640)
- Diverse sources of C. difficile infection identified on whole-genome sequencing. (2013) (584)
- epic2: National Evidence-Based Guidelines for Preventing Healthcare-Associated Infections in NHS Hospitals in England (2007) (477)
- European Society of Clinical Microbiology and Infectious Diseases (ESCMID): data review and recommendations for diagnosing Clostridium difficile-infection (CDI). (2009) (440)
- European Society of Clinical Microbiology and Infectious Diseases: update of the diagnostic guidance document for Clostridium difficile infection. (2016) (431)
- Differences in outcome according to Clostridium difficile testing method: a prospective multicentre diagnostic validation study of C difficile infection (2013) (407)
- Clostridium difficile infection (2015) (386)
- Once-weekly dalbavancin versus daily conventional therapy for skin infection. (2014) (351)
- Comparison of Nine Commercially Available Clostridium difficile Toxin Detection Assays, a Real-Time PCR Assay for C. difficile tcdB, and a Glutamate Dehydrogenase Detection Assay to Cytotoxin Testing and Cytotoxigenic Culture Methods (2009) (348)
- Interventions to improve antibiotic prescribing practices for hospital inpatients. (2013) (344)
- Bezlotoxumab for Prevention of Recurrent Clostridium difficile Infection (2017) (342)
- Infection control measures to limit the spread of Clostridium difficile. (2008) (323)
- Update of Clostridium difficile infection due to PCR ribotype 027 in Europe, 2008. (2008) (315)
- Guidelines for the management of hospital-acquired pneumonia in the UK: Report of the Working Party on Hospital-Acquired Pneumonia of the British Society for Antimicrobial Chemotherapy (2008) (310)
- Underdiagnosis of Clostridium difficile across Europe: the European, multicentre, prospective, biannual, point-prevalence study of Clostridium difficile infection in hospitalised patients with diarrhoea (EUCLID). (2014) (309)
- Prediction of Susceptibility to First‐Line Tuberculosis Drugs by DNA Sequencing (2018) (295)
- Comparison of the effect of detergent versus hypochlorite cleaning on environmental contamination and incidence of Clostridium difficile infection. (2003) (286)
- Clinical and economic burden of Clostridium difficile infection in Europe: a systematic review of healthcare-facility-acquired infection. (2012) (271)
- Rapid, comprehensive, and affordable mycobacterial diagnosis with whole-genome sequencing: a prospective study (2016) (271)
- The epic project: developing national evidence-based guidelines for preventing healthcare associated infections. Phase I: Guidelines for preventing hospital-acquired infections. Department of Health (England). (2001) (271)
- Financial burden of hospital-acquired Clostridium difficile infection. (1996) (269)
- Emergence of reduced susceptibility to metronidazole in Clostridium difficile. (2008) (263)
- A pilot study of rapid benchtop sequencing of Staphylococcus aureus and Clostridium difficile for outbreak detection and surveillance (2012) (258)
- Effects of control interventions on Clostridium difficile infection in England: an observational study (2017) (252)
- Clostridium difficile infection: epidemiology, diagnosis and understanding transmission (2016) (246)
- Reduced susceptibility to chlorhexidine in staphylococci: is it increasing and does it matter? (2012) (240)
- Pan-European longitudinal surveillance of antibiotic resistance among prevalent Clostridium difficile ribotypes. (2015) (239)
- Characterisation of Clostridium difficile Hospital Ward–Based Transmission Using Extensive Epidemiological Data and Molecular Typing (2012) (238)
- Treatment of health-care-associated infections caused by Gram-negative bacteria: a consensus statement. (2008) (237)
- Integrated analysis of CANVAS 1 and 2: phase 3, multicenter, randomized, double-blind studies to evaluate the safety and efficacy of ceftaroline versus vancomycin plus aztreonam in complicated skin and skin-structure infection. (2010) (233)
- Changing epidemiology of Clostridium difficile infection following the introduction of a national ribotyping-based surveillance scheme in England. (2012) (233)
- Descriptive study of intravenous immunoglobulin for the treatment of recurrent Clostridium difficile diarrhoea. (2004) (227)
- Multilocus Sequence Typing of Clostridium difficile (2009) (219)
- Antibiotic strategies in the era of multidrug resistance (2016) (215)
- Microevolutionary analysis of Clostridium difficile genomes to investigate transmission (2012) (209)
- Shedding of SARS-CoV-2 in feces and urine and its potential role in person-to-person transmission and the environment-based spread of COVID-19 (2020) (207)
- Relationship Between Bacterial Strain Type, Host Biomarkers, and Mortality in Clostridium difficile Infection (2013) (206)
- Complicated skin and skin-structure infections and catheter-related bloodstream infections: noninferiority of linezolid in a phase 3 study. (2009) (202)
- CANVAS 2: the second Phase III, randomized, double-blind study evaluating ceftaroline fosamil for the treatment of patients with complicated skin and skin structure infections. (2010) (201)
- The potential for airborne dispersal of Clostridium difficile from symptomatic patients. (2010) (198)
- Predictors of First Recurrence of Clostridium difficile Infection: Implications for Initial Management (2012) (196)
- Recurrence of symptoms in Clostridium difficile infection--relapse or reinfection? (1998) (193)
- Comparative Analysis of Prevalence, Risk Factors, and Molecular Epidemiology of Antibiotic-Associated Diarrhea Due to Clostridium difficile, Clostridium perfringens, and Staphylococcus aureus (2006) (188)
- Characterization of the Sporulation Initiation Pathway of Clostridium difficile and Its Role in Toxin Production (2009) (182)
- Efficacy of Hospital Cleaning Agents and Germicides Against Epidemic Clostridium difficile Strains (2007) (178)
- Hospital disinfectants and spore formation by Clostridium difficile (2000) (176)
- Role of environmental cleaning in controlling an outbreak of Acinetobacter baumannii on a neurosurgical intensive care unit. (2004) (174)
- Rapid diagnosis of central-venous-catheter-related bloodstream infection without catheter removal (1999) (171)
- The slime of coagulase-negative staphylococci: biochemistry and relation to adherence. (1993) (170)
- Use of perioperative mupirocin to prevent methicillin-resistant Staphylococcus aureus (MRSA) orthopaedic surgical site infections. (2003) (168)
- Development and Validation of an Internationally-Standardized, High-Resolution Capillary Gel-Based Electrophoresis PCR-Ribotyping Protocol for Clostridium difficile (2015) (168)
- Update of Clostridium difficile-associated disease due to PCR ribotype 027 in Europe. (2007) (166)
- Understanding Clostridium difficile Colonization (2018) (160)
- Clinical Clostridium difficile: Clonality and Pathogenicity Locus Diversity (2011) (159)
- CANVAS 1: the first Phase III, randomized, double-blind study evaluating ceftaroline fosamil for the treatment of patients with complicated skin and skin structure infections. (2010) (146)
- Evolutionary History of the Clostridium difficile Pathogenicity Locus (2013) (146)
- Clostridium difficile: a European perspective. (2013) (143)
- Diarrhoea caused by Clostridium difficile: response time for treatment with metronidazole and vancomycin. (1995) (143)
- Correlation between enterococcal biofilm formation in vitro and medical-device-related infection potential in vivo. (2003) (136)
- Diversity of Clostridium difficile PCR ribotypes in Europe: results from the European, multicentre, prospective, biannual, point-prevalence study of Clostridium difficile infection in hospitalised patients with diarrhoea (EUCLID), 2012 and 2013. (2016) (136)
- Aeromonas infections and their treatment. (1995) (135)
- Preventive and therapeutic strategies in critically ill patients with highly resistant bacteria (2015) (135)
- Clostridium difficile: changing epidemiology and new treatment options (2007) (134)
- Comparison of the efficacy of ramoplanin and vancomycin in both in vitro and in vivo models of clindamycin-induced Clostridium difficile infection. (2005) (134)
- Clinical Practice Guideline by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA): 2021 Focused Update Guidelines on Management of Clostridioides difficile Infection in Adults. (2021) (134)
- Measurement of ampicillin, vancomycin, linezolid and gentamicin activity against enterococcal biofilms. (2006) (131)
- Systematic Review of Antimicrobial Drug Prescribing in Hospitals (2006) (127)
- Current application and future perspectives of molecular typing methods to study Clostridium difficile infections. (2013) (123)
- In situ diagnosis of intravascular catheter-related bloodstream infection: A comparison of quantitative culture, differential time to positivity, and endoluminal brushing (2005) (118)
- Evaluation of a novel endoluminal brush method for in situ diagnosis of catheter related sepsis. (1997) (117)
- Antimicrobial-resistant pathogens in animals and man: prescribing, practices and policies. (2010) (116)
- Relatedness of Human and Animal Clostridium difficile PCR Ribotype 078 Isolates Determined on the Basis of Multilocus Variable-Number Tandem-Repeat Analysis and Tetracycline Resistance (2010) (115)
- Potential for aerosolization of Clostridium difficile after flushing toilets: the role of toilet lids in reducing environmental contamination risk. (2012) (113)
- Molecular epidemiology of endemic Clostridium difficile infection (2001) (113)
- The effects of storage conditions on viability of Clostridium difficile vegetative cells and spores and toxin activity in human faeces (2003) (113)
- Prospective evaluation of environmental contamination by Clostridium difficile in isolation side rooms. (2001) (113)
- Reference assays for Clostridium difficile infection: one or two gold standards? (2010) (112)
- Models for the study of Clostridium difficile infection (2012) (111)
- Antibiotics and Clostridium difficile. (1999) (110)
- International Clostridium difficile animal strain collection and large diversity of animal associated strains (2014) (110)
- Long-term surveillance of cefotaxime and piperacillin-tazobactam prescribing and incidence of Clostridium difficile diarrhoea. (2004) (110)
- Effect of metronidazole on growth and toxin production by epidemic Clostridium difficile PCR ribotypes 001 and 027 in a human gut model. (2007) (107)
- Linezolid compared with teicoplanin for the treatment of suspected or proven Gram-positive infections. (2004) (104)
- Towards precision medicine in sepsis: a position paper from the European Society of Clinical Microbiology and Infectious Diseases. (2018) (102)
- Evaluation of NVB302 versus vancomycin activity in an in vitro human gut model of Clostridium difficile infection. (2013) (102)
- Reduced susceptibility of Clostridium difficile to metronidazole. (2001) (102)
- Effects of piperacillin/tazobactam on Clostridium difficile growth and toxin production in a human gut model. (2005) (101)
- Point-Counterpoint: What Is the Current Role of Algorithmic Approaches for Diagnosis ofClostridium difficile Infection? (2010) (101)
- Accuracy of serology for the diagnosis of Helicobacter pylori infection--a comparison of eight kits. (1996) (99)
- Overcoming barriers to effective recognition and diagnosis of Clostridium difficile infection. (2012) (98)
- Point-Counterpoint: What Is the Optimal Approach for Detection of Clostridium difficile Infection? (2017) (98)
- The ClosER study: results from a three-year pan-European longitudinal surveillance of antibiotic resistance among prevalent Clostridium difficile ribotypes, 2011-2014. (2017) (97)
- Summary of ceftaroline fosamil clinical trial studies and clinical safety. (2012) (96)
- Effects of cefotaxime and desacetylcefotaxime upon Clostridium difficile proliferation and toxin production in a triple-stage chemostat model of the human gut. (2003) (94)
- Trends over time in Escherichia coli bloodstream infections, urinary tract infections, and antibiotic susceptibilities in Oxfordshire, UK, 1998-2016: a study of electronic health records. (2018) (93)
- European perspective and update on the management of complicated skin and soft tissue infections due to methicillin-resistant Staphylococcus aureus after more than 10 years of experience with linezolid. (2014) (88)
- Renal Failure and Leukocytosis Are Predictors of a Complicated Course of Clostridium difficile Infection if Measured on Day of Diagnosis (2012) (88)
- Clostridium difficile infection: responses, relapses and re-infections. (1992) (88)
- Recombinational switching of the Clostridium difficile S-layer and a novel glycosylation gene cluster revealed by large-scale whole-genome sequencing. (2013) (85)
- Laboratory diagnosis of Clostridium perfringens antibiotic-associated diarrhoea. (2002) (82)
- Mycobacterial DNA Extraction for Whole-Genome Sequencing from Early Positive Liquid (MGIT) Cultures (2015) (81)
- Tigecycline does not induce proliferation or cytotoxin production by epidemic Clostridium difficile strains in a human gut model. (2006) (80)
- National Clostridium difficile Standards Group: Report to the Department of Health. (2004) (78)
- Guidelines on appropriate indications for upper gastrointestinal endoscopy (1995) (78)
- Prevalence of Methicillin-Resistant Staphylococcus aureus Colonization Among Older Residents of Care Homes in the United Kingdom (2007) (78)
- Activity of vancomycin against epidemic Clostridium difficile strains in a human gut model. (2009) (77)
- DNA Sequencing Predicts 1st-Line Tuberculosis Drug Susceptibility Profiles (2018) (76)
- Clostridium difficile infection and pseudomembranous colitis (2003) (75)
- Decreased effectiveness of metronidazole for the treatment of Clostridium difficile infection? (2008) (74)
- Efficacy and safety of ridinilazole compared with vancomycin for the treatment of Clostridium difficile infection: a phase 2, randomised, double-blind, active-controlled, non-inferiority study (2017) (74)
- The Control of Methicillin-Resistant Staphylococcus aureus Blood Stream Infections in England (2015) (73)
- Value of lysozyme agar incorporation and alkaline thioglycollate exposure for the environmental recovery of Clostridium difficile. (2000) (73)
- Enterococcal intravascular catheter-related bloodstream infection: management and outcome of 61 consecutive cases. (2002) (71)
- Performance of the Innova SARS-CoV-2 antigen rapid lateral flow test in the Liverpool asymptomatic testing pilot: population based cohort study (2021) (71)
- Surveillance for mupirocin resistance following introduction of routine peri-operative prophylaxis with nasal mupirocin. (2006) (70)
- Update on linezolid: the first oxazolidinone antibiotic (2005) (70)
- Antibiotic resistance prediction for Mycobacterium tuberculosis from genome sequence data with Mykrobe (2019) (69)
- Covert dissemination of carbapenemase-producing Klebsiella pneumoniae (KPC) in a successfully controlled outbreak: long- and short-read whole-genome sequencing demonstrate multiple genetic modes of transmission (2017) (69)
- Use of Highly Discriminatory Fingerprinting to Analyze Clusters of Clostridium difficile Infection Cases Due to Epidemic Ribotype 027 Strains (2008) (68)
- Epidemiology of Clostridium difficile in infants in Oxfordshire, UK: Risk factors for colonization and carriage, and genetic overlap with regional C. difficile infection strains (2017) (68)
- Comparison of Multilocus Variable-Number Tandem-Repeat Analysis and Whole-Genome Sequencing for Investigation of Clostridium difficile Transmission (2013) (67)
- Effects of Exposure of Clostridium difficile PCR Ribotypes 027 and 001 to Fluoroquinolones in a Human Gut Model (2008) (66)
- Role of environmental cleaning in controlling an outbreak of Acinetobacter baumannii on a neurosurgical intensive care unit. (2005) (66)
- Multicenter, Double-Blind, Randomized, Phase 2 Study Evaluating the Novel Antibiotic Cadazolid in Patients with Clostridium difficile Infection (2015) (66)
- Diagnosis of central venous catheter related sepsis--a critical look inside. (1999) (64)
- In vitro activity of cadazolid against clinically relevant Clostridium difficile isolates and in an in vitro gut model of C. difficile infection. (2014) (63)
- Emergence and spread of predominantly community-onset Clostridium difficile PCR ribotype 244 infection in Australia, 2010 to 2012. (2015) (63)
- Incidence and impact of Clostridium difficile infection in the UK, 1993-1996. (1998) (63)
- Is reduced susceptibility to disinfectants and antiseptics a risk in healthcare settings? A point/counterpoint review. (2014) (62)
- Risk factors for Clostridium difficile infection in hospitalized patients with community-acquired pneumonia. (2016) (62)
- Comparison of oritavancin versus vancomycin as treatments for clindamycin-induced Clostridium difficile PCR ribotype 027 infection in a human gut model. (2008) (62)
- Guidance document for prevention of Clostridium difficile infection in acute healthcare settings. (2018) (61)
- Clostridium difficile Mixed Infection and Reinfection (2011) (61)
- Epidemiology, diagnosis and treatment of Clostridium difficile infection (2012) (61)
- Evidence for antibiotic induced Clostridium perfringens diarrhoea. (2001) (60)
- Escherichia coli bacteraemia: 2 years of prospective regional surveillance (2010-12). (2014) (60)
- How to: Surveillance of Clostridium difficile infections. (2017) (59)
- Management of complicated skin and soft tissue infections with a special focus on the role of newer antibiotics (2018) (58)
- Influence of carbon dioxide on the surface characteristics and adherence potential of coagulase-negative staphylococci (1990) (58)
- Comparative efficacy of treatments for Clostridium difficile infection: a systematic review and network meta-analysis. (2018) (58)
- Successful treatment of simulated Clostridium difficile infection in a human gut model by fidaxomicin first line and after vancomycin or metronidazole failure. (2014) (57)
- The tide of antimicrobial resistance and selection. (2009) (57)
- Standardised surveillance of Clostridium difficile infection in European acute care hospitals: a pilot study, 2013. (2016) (57)
- Diverse Temperate Bacteriophage Carriage in Clostridium difficile 027 Strains (2012) (57)
- Cleaning up Clostridium difficile infection (1996) (56)
- Safety of Dalbavancin in the Treatment of Skin and Skin Structure Infections: A Pooled Analysis of Randomized, Comparative Studies (2015) (54)
- Aeromonas spp as a potential cause of diarrhoea in children. (1992) (54)
- DNA fingerprinting analysis of coagulase negative staphylococci implicated in catheter related bloodstream infections (2002) (54)
- In vitro activity of new generation fluoroquinolones against genotypically distinct and indistinguishable Clostridium difficile isolates. (2000) (53)
- Role of cephalosporins in the era of Clostridium difficile infection (2016) (53)
- Efficacy of linezolid versus comparator therapies in Gram-positive infections. (2003) (53)
- Two Distinct Patterns of Clostridium difficile Diversity Across Europe Indicating Contrasting Routes of Spread (2018) (51)
- Two Distinct Patterns of Clostridium difficile Diversity Across Europe Indicating Contrasting Routes of Spread (2018) (51)
- Antimicrobial Resistance and Reduced Susceptibility in Clostridium difficile: Potential Consequences for Induction, Treatment, and Recurrence of C. difficile Infection (2015) (51)
- A Role for Tetracycline Selection in Recent Evolution of Agriculture-Associated Clostridium difficile PCR Ribotype 078 (2019) (50)
- Each lumen is a potential source of central venous catheter-related bloodstream infection. (2003) (49)
- Prospective evaluation of hospital isolation room capacity. (2006) (49)
- Molecular Epidemiology of Endemic Clostridium difficile Infection and the Significance of Subtypes of the United Kingdom Epidemic Strain (PCR Ribotype 1) (2005) (49)
- Tolevamer Is Not Efficacious in the Neutralization of Cytotoxin in a Human Gut Model of Clostridium difficile Infection (2009) (47)
- Enhanced surveillance of Clostridium difficile infection occurring outside hospital, England, 2011 to 2013. (2016) (47)
- Effects of carbon dioxide and sub-lethal levels of antibiotics on adherence of coagulase-negative staphylococci to polystyrene and silicone rubber. (1991) (46)
- Surveillance for resistance to metronidazole and vancomycin in genotypically distinct and UK epidemic Clostridium difficile isolates in a large teaching hospital. (2005) (46)
- Assessment of self taken swabs versus clinician taken swab cultures for diagnosing gonorrhoea in women: single centre, diagnostic accuracy study (2012) (46)
- Diagnostic pitfalls in Clostridium difficile infection. (2015) (46)
- New and emerging therapies for Clostridium difficile infection (2016) (45)
- Impact of recurrent Clostridium difficile infection: hospitalization and patient quality of life (2017) (44)
- Assessment of best single sample for finding chlamydia in women with and without symptoms: a diagnostic test study (2012) (44)
- Gastrointestinal disorders and the critically ill. Clostridium difficile infection and pseudomembranous colitis. (2003) (43)
- Clostridium difficile: Investigating Transmission Patterns Between Infected and Colonized Patients Using Whole Genome Sequencing (2018) (43)
- Methicillin-resistant Staphylococcus aureus in trauma and orthopaedic practice. (2005) (42)
- A Phase 3, Randomized, Double-Blind, Multicenter Study to Evaluate the Safety and Efficacy of Intravenous Iclaprim Vs Vancomycin for the Treatment of Acute Bacterial Skin and Skin Structure Infections Suspected or Confirmed to be Due to Gram-Positive Pathogens: REVIVE-1 (2017) (42)
- In situ measurement of linezolid and vancomycin concentrations in intravascular catheter-associated biofilm. (2001) (41)
- Contribution to Clostridium Difficile Transmission of Symptomatic Patients With Toxigenic Strains Who Are Fecal Toxin Negative (2017) (41)
- Antimicrobial activity of LFF571 and three treatment agents against Clostridium difficile isolates collected for a pan-European survey in 2008: clinical and therapeutic implications. (2013) (41)
- Development and Validation of a Chemostat Gut Model To Study Both Planktonic and Biofilm Modes of Growth of Clostridium difficile and Human Microbiota (2014) (41)
- Importance of medium and atmosphere type to both slime production and adherence by coagulase-negative staphylococci. (1992) (41)
- Treatment of Clostridium difficile infection. (1998) (40)
- Subcutaneous fluid administration--better than the intravenous approach? (1999) (39)
- The cost of hospital-acquired infection and the value of infection control. (2000) (39)
- Adaptation of the WHO Essential Medicines List for national antibiotic stewardship policy in England: being AWaRe. (2019) (38)
- Characterization of cell envelope proteins of Staphylococcus epidermidis cultured in human peritoneal dialysate (1991) (37)
- Infection due to C. difficile ribotype 078: first report of cases in the Republic of Ireland. (2010) (37)
- Comparison of planktonic and biofilm-associated communities of Clostridium difficile and indigenous gut microbiota in a triple-stage chemostat gut model. (2014) (37)
- A randomised phase 1 study to investigate safety, pharmacokinetics and impact on gut microbiota following single and multiple oral doses in healthy male subjects of SMT19969, a novel agent for Clostridium difficile infections (2015) (37)
- Whole genome sequencing and de novo assembly identifies Sydney-like variant noroviruses and recombinants during the winter 2012/2013 outbreak in England (2013) (37)
- Enterococci and hospital laundry (1995) (37)
- Five-year Pan-European, longitudinal surveillance of Clostridium difficile ribotype prevalence and antimicrobial resistance: the extended ClosER study (2019) (36)
- Ridinilazole: a novel therapy for Clostridium difficile infection. (2016) (36)
- Antimicrobial treatment of pulmonary colonization and infection by pseudomonas aeruginosa in cystic fibrosis patients. (1997) (36)
- Fidaxomicin: a new option for the treatment of Clostridium difficile infection. (2012) (36)
- Pulsed-Field Gel Electrophoresis Can Yield DNA Fingerprints of Degradation-Susceptible Clostridium difficile Strains (2002) (35)
- Role of antibody response in outcome of antibiotic-associated diarrhoea (2001) (35)
- Influence of carbon dioxide on growth and antibiotic susceptibility of coagulase-negative staphylococci cultured in human peritoneal dialysate (1990) (35)
- Healthcare-associated COVID-19 in England: A national data linkage study (2021) (35)
- Evaluation of linezolid for the treatment of Clostridium difficile infection caused by epidemic strains using an in vitro human gut model. (2011) (35)
- SMT19969 as a treatment for Clostridium difficile infection: an assessment of antimicrobial activity using conventional susceptibility testing and an in vitro gut model (2014) (34)
- Effectiveness of deep cleaning followed by hydrogen peroxide decontamination during high Clostridium difficile infection incidence. (2014) (34)
- Effect of extended perioperative antibiotic prophylaxis on intravascular catheter colonization and infection in cardiothoracic surgery patients. (2003) (34)
- Co-amoxiclav induces proliferation and cytotoxin production of Clostridium difficile ribotype 027 in a human gut model. (2012) (33)
- The longitudinal prevalence of MRSA in care home residents and the effectiveness of improving infection prevention knowledge and practice on colonisation using a stepped wedge study design (2012) (33)
- Laboratory diagnosis of Clostridium difficile infection: in a state of transition or confusion or both? (2011) (33)
- A Phase 3, Randomized, Double-Blind, Multicenter Study To Evaluate the Safety and Efficacy of Intravenous Iclaprim versus Vancomycin for Treatment of Acute Bacterial Skin and Skin Structure Infections Suspected or Confirmed To Be Due to Gram-Positive Pathogens (REVIVE-2 Study) (2018) (33)
- Toxoplasmosis and systemic lupus erythematosus. (1990) (33)
- Effect of pH changes in cerebrospinal fluid specimens on bacterial survival and antigen test results. (1996) (33)
- Comparison of Control of Clostridium difficile Infection in Six English Hospitals Using Whole-Genome Sequencing (2017) (32)
- Effectiveness of a short (4 day) course of oritavancin in the treatment of simulated Clostridium difficile infection using a human gut model. (2012) (32)
- Efficacy of surotomycin in an in vitro gut model of Clostridium difficile infection. (2014) (31)
- The use of a rapid in situ test in the detection of central venous catheter-related bloodstream infection: a prospective study. (2003) (31)
- Clostridium difficile infections of the gut: the unanswered questions. (1998) (31)
- Evaluation of chromogenic meticillin-resistant Staphylococcus aureus media: sensitivity versus turnaround time. (2012) (31)
- Evaluation of the effect of oritavancin on Clostridium difficile spore germination, outgrowth and recovery. (2013) (30)
- An Assessment of Bacterial Dysbiosis in Pouchitis Using Terminal Restriction Fragment Length Polymorphisms of 16S Ribosomal DNA From Pouch Effluent Microbiota (2009) (30)
- Improving early management of bloodstream infection: a quality improvement project (2008) (30)
- In vitro susceptibility of Clostridium difficile to SMT19969 and comparators, as well as the killing kinetics and post-antibiotic effects of SMT19969 and comparators against C. difficile (2015) (30)
- Microbiological comparison of hand-drying methods: the potential for contamination of the environment, user, and bystander. (2014) (30)
- Measurement of toxin production by Clostridium difficile (2006) (30)
- Antibodies for Treatment of Clostridium difficile Infection (2014) (30)
- Susceptibility of Clostridium difficile isolates from a Phase 2 clinical trial of cadazolid and vancomycin in C. difficile infection (2015) (29)
- Cadazolid for the treatment of Clostridium difficile infection: results of two double-blind, placebo-controlled, non-inferiority, randomised phase 3 trials. (2019) (29)
- Variation in the expression of cell envelope proteins of coagulase-negative staphylococci cultured under iron-restricted conditions in human peritoneal dialysate. (1991) (29)
- Lack of evidence for an unmet need to treat Clostridium difficile infection in infants aged <2 years: expert recommendations on how to address this issue. (2015) (29)
- Early experience with linezolid for infections in orthopaedics. (2006) (28)
- Nitazoxanide is active against Clostridium difficile strains with reduced susceptibility to metronidazole. (2011) (28)
- Clinical Practice Guideline by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA): 2021 Focused Update Guidelines on Management of Clostridioides difficile Infection in Adults. (2021) (28)
- Viral gastroenteritis increases the reports of Clostridium difficile infection. (2007) (27)
- Efficacy of alternative fidaxomicin dosing regimens for treatment of simulated Clostridium difficile infection in an in vitro human gut model. (2015) (27)
- Omadacycline Gut Microbiome Exposure Does Not Induce Clostridium difficile Proliferation or Toxin Production in a Model That Simulates the Proximal, Medial, and Distal Human Colon (2018) (27)
- Environmental contamination by bacteria in hospital washrooms according to hand-drying method: a multi-centre study. (2018) (27)
- A five year outbreak of methicillin-susceptible Staphylococcus aureus phage type 53,85 in a regional neonatal unit (2000) (27)
- Is there a relationship between the presence of the binary toxin genes in Clostridium difficile strains and the severity of C. difficile infection (CDI)? (2017) (27)
- Association of Fidaxomicin with C. difficile Spores: Effects of Persistence on Subsequent Spore Recovery, Outgrowth and Toxin Production (2016) (27)
- MRSA prevention strategies and current guidelines. (2011) (26)
- Meticillin-resistant Staphylococcus aureus in elderly residents of care homes: colonization rates and molecular epidemiology. (2013) (26)
- Delayed Development of Linezolid Resistance in Staphylococcus aureus following Exposure to Low Levels of Antimicrobial Agents (2008) (26)
- The predictive value of quantitative nucleic acid amplification detection of Clostridium difficile toxin gene for faecal sample toxin status and patient outcome (2018) (26)
- Antibiotic therapy and Clostridium difficile infection – primum non nocere – first do no harm (2015) (25)
- Evidence to support the existence of subgroups within the UK epidemic Clostridium difficile strain (PCR ribotype 1). (2003) (25)
- Evidence for low risk of Clostridium difficile infection associated with tigecycline. (2007) (25)
- In situ endoluminal brushing: a safe technique for the diagnosis of catheter-related bloodstream infection. (2004) (25)
- An Enhanced DNA Fingerprinting Service To Investigate Potential Clostridium difficile Infection Case Clusters Sharing the Same PCR Ribotype (2011) (25)
- Biofilms harbour Clostridioides difficile, serving as a reservoir for recurrent infection (2021) (24)
- Antibiotic activity against genotypically distinct and indistinguishable Clostridium difficile isolates. (2001) (24)
- The Efficacy and Safety of Fecal Microbiota Transplant for Recurrent Clostridiumdifficile Infection: Current Understanding and Gap Analysis (2020) (24)
- Susceptibility of alpha-haemolytic streptococci causing endocarditis to benzylpenicillin and ten cephalosporins. (1993) (24)
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- Clostridium difficile trehalose metabolism variants are common and not associated with adverse patient outcomes when variably present in the same lineage (2019) (24)
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- Susceptibility of Clostridium difficile Isolates of Varying Antimicrobial Resistance Phenotypes to SMT19969 and 11 Comparators (2015) (23)
- Morbidity and mortality associated with Clostridium difficile ribotype 078: a case-case study. (2012) (23)
- Clostridium difficile ribotype 126 in southern Taiwan: a cluster of three symptomatic cases. (2014) (23)
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- Survey of Clostridium difficile infection surveillance systems in Europe, 2011. (2016) (22)
- In vitro susceptibility of genotypically distinct and clonal Clostridium difficile strains to oritavancin. (2008) (22)
- Growth of Aeromonas spp. at 4°C and related toxin production (1993) (21)
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- Rapid spread of penicillin-resistant Streptococcus pneumoniae among high-risk hospital inpatients and the role of molecular typing in outbreak confirmation. (2003) (21)
- The pitfalls of laboratory diagnostics of Clostridium difficile infection. (2018) (21)
- Tigecycline and the need for a new broad-spectrum antibiotic class. (2006) (21)
- Managing skin and soft-tissue infection and nosocomial pneumonia caused by MRSA: a 2014 follow-up survey. (2015) (21)
- Variability in testing policies and impact on reported Clostridium difficile infection rates: results from the pilot Longitudinal European Clostridium difficile Infection Diagnosis surveillance study (LuCID) (2016) (20)
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- Laboratory studies on coagulase-negative staphylococci from CAPD-associated peritonitis. (1985) (20)
- Potential of lactoferrin to prevent antibiotic-induced Clostridium difficile infection (2016) (20)
- Continuous Ambulatory Peritoneal Dialysis (CAPD) Peritonitis: The Effect of Antibiotic on the Adherence of Coagulase-Negative Staphylococci to Silicone Rubber Catheter Material (1989) (19)
- Survey of diagnostic and typing capacity for Clostridium difficile infection in Europe, 2011 and 2014. (2016) (19)
- Outer membrane protein profiles of Xanthomonas maltophilia isolates displaying temperature-dependent susceptibility to gentamicin. (1994) (19)
- Serious hospital infections Introduction (1999) (19)
- Intervention planning for Antibiotic Review Kit (ARK): a digital and behavioural intervention to safely review and reduce antibiotic prescriptions in acute and general medicine (2019) (19)
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- Quinolones and Salmonella gastroenteritis. (1992) (18)
- Phenotypic methods for speciating clinical Aeromonas isolates. (1992) (18)
- Sensitivity of Single-Molecule Array Assays for Detection of Clostridium difficile Toxins in Comparison to Conventional Laboratory Testing Algorithms (2018) (18)
- Evaluation of antimicrobial activity of ceftaroline against Clostridium difficile and propensity to induce C. difficile infection in an in vitro human gut model. (2013) (18)
- Glove powder: implications for infection control. (1999) (18)
- Binding of teicoplanin and vancomycin to polymer surfaces. (1994) (18)
- Clostridioides difficile ribotypes 001 and 126 were predominant in Tehran healthcare settings from 2004 to 2018: a 14-year-long cross-sectional study (2020) (18)
- Mixed infection by Clostridium difficile in an in vitro model of the human gut. (2013) (17)
- Short-Term Genome Stability of Serial Clostridium difficile Ribotype 027 Isolates in an Experimental Gut Model and Recurrent Human Disease (2013) (17)
- Are methicillin-resistant Staphylococcus aureus that produce Panton-Valentine leucocidin (PVL) found among residents of care homes? (2008) (17)
- Metagenomics reveals impact of geography and acute diarrheal disease on the Central Indian human gut microbiome (2020) (17)
- Combined cervical swab and urine specimens for PCR diagnosis of genital Chlamydia trachomatis infection (2000) (16)
- Ciprofloxacin and Clostridium difficile infection (1990) (16)
- Molecular, microbiological and clinical characterization of Clostridium difficile isolates from tertiary care hospitals in Colombia (2017) (16)
- Bezlotoxumab Alone and With Actoxumab for Prevention of Recurrent Clostridium difficile Infection in Patients on Standard of Care Antibiotics: Integrated Results of 2 Phase 3 Studies (MODIFY I and MODIFY II) (2015) (16)
- Molecular epidemiology of Clostridioides (previously Clostridium) difficile isolates from a university hospital in Minas Gerais, Brazil. (2019) (16)
- Role of surface energy and nano-roughness in the removal efficiency of bacterial contamination by nonwoven wipes from frequently touched surfaces (2017) (16)
- Data are not widely applicable (2007) (16)
- Reporting elevated vancomycin minimum inhibitory concentration in methicillin-resistant Staphylococcus aureus: consensus by an International Working Group (2019) (16)
- Serum luteal phase progesterone in women undergoing frozen embryo transfer in assisted conception: a systematic review and meta-analysis. (2021) (16)
- Efficacy of Tigecycline in Complicated Skin and Skin Structure Infections and Complicated Intra-abdominal Infections (2005) (16)
- Effectiveness of topical chlorhexidine powder as an alternative to hexachlorophane for the control of Staphylococcus aureus in neonates. (2004) (16)
- Hazards of multiple use of pharmaceutical solutions (2000) (15)
- Dissemination of multiple carbapenem resistance genes in an in vitro gut model simulating the human colon. (2019) (15)
- Monomicrobial Clostridium difficile bacteraemias and relationship to gut infection. (2011) (15)
- Clostridium difficile--setting the scene. (1998) (15)
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- Molecular diagnostic techniques (2003) (15)
- A MLST Clade 2 Clostridium difficile strain with a variant TcdB induces severe inflammatory and oxidative response associated with mucosal disruption. (2016) (15)
- Extremely low prevalence of UK Staphylococcus aureus isolates with reduced susceptibility to vancomycin. (2001) (15)
- Clarithromycin and risk of Clostridium difficile-associated diarrhoea. (2001) (15)
- Mecillinam: a low-risk antimicrobial agent for induction of Clostridium difficile infection in an in vitro human gut model. (2009) (15)
- Pooled analysis of the phase 3 REVIVE trials: randomised, double-blind studies to evaluate the safety and efficacy of iclaprim versus vancomycin for treatment of acute bacterial skin and skin-structure infections. (2018) (15)
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- Effect of Endogenous Clostridioides difficile Toxin Antibodies on Recurrence of C. difficile Infection. (2020) (14)
- Preventing biliary stent occlusion (1994) (14)
- Ureidopenicillins and risk of Clostridium difficile infection. (2001) (14)
- Antibiotic prescribing as a risk factor for MRSA. (2005) (14)
- Lack of evidence for increased adherent growth in broth or human serum of clinically significant coagulase-negative staphylococci. (1994) (14)
- Combating resistance while maintaining innovation: the future of antimicrobial stewardship. (2019) (14)
- A comparison of culture and PCR to determine the prevalence of ampicillin-resistant bacteria in the faecal flora of general practice patients. (2001) (14)
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- Comparison of the Vidas C. difficile GDH Automated Enzyme-Linked Fluorescence Immunoassay (ELFA) with Another Commercial Enzyme Immunoassay (EIA) (Quik Chek-60), Two Selective Media, and a PCR Assay for gluD for Detection of Clostridium difficile in Fecal Samples (2015) (14)
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- Clostridium difficile infection: appendix. (1998) (12)
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- Faecal concentrations of piperacillin and tazobactam in elderly patients. (2001) (11)
- High prevalence of subclass-specific binding and neutralizing antibodies against Clostridium difficile toxins in adult cystic fibrosis sera: possible mode of immunoprotection against symptomatic C. difficile infection (2017) (11)
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- The start of another infection prevention learning curve: reducing healthcare-associated Gram-negative bloodstream infections. (2017) (10)
- Perturbations of the gut microbiome in anti-CCP positive individuals at risk of developing rheumatoid arthritis. (2020) (10)
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- Effect of fluoroquinolone resistance mutation Thr-82→Ile on Clostridioides difficile fitness (2019) (9)
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- A simple prophylaxis regimen for MRSA: its impact on the incidence of infection in patients undergoing liver resection. (2009) (9)
- Subtyping of Clostridium difficile PCR ribotypes 591, 106 and 002, the dominant strain types circulating in Medellin, Colombia (2018) (9)
- Ultrasensitive Detection of Clostridium difficile Toxins Reveals Suboptimal Accuracy of Toxin Gene Cycle Thresholds for Toxin Predictions (2019) (9)
- Diverse sources of C. difficile infection. (2014) (9)
- In Vitro Activity of Omadacycline, a New Tetracycline Analog, and Comparators against Clostridioides difficile (2020) (9)
- An In Vitro Model of the Human Colon: Studies of Intestinal Biofilms and Clostridium difficile Infection. (2016) (9)
- Diagnosis of Clostridium difficile-associated diarrhea and odor. (2007) (9)
- Global Landscape of Clostridioides Difficile Phylogeography, Antibiotic Susceptibility, and Toxin Polymorphisms by Post-Hoc Whole-Genome Sequencing from the MODIFY I/II Studies (2021) (9)
- Swab-yourself trial with economic monitoring and testing for infections collectively (SYSTEMATIC): Part 1. A diagnostic accuracy, and cost-effectiveness, study comparing clinician-taken versus self-taken rectal and pharyngeal samples for the diagnosis of gonorrhoea and chlamydia. (2020) (9)
- Peritonitis complicating continuous ambulatory peritoneal dialysis in Nottingham 1983-1988. (1991) (8)
- Malignant clear cell hidradenoma of the vulva: report of a unique case and review of the literature. (2008) (8)
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- A Review of Mixed Strain Clostridium difficile Colonization and Infection (2019) (8)
- In Vitro Activities of MCB3681 and Eight Comparators against Clostridium difficile Isolates with Known Ribotypes and Diverse Geographical Spread (2016) (8)
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- Antibiotic use and abuse (1998) (7)
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- Influence of Diagnostic Method on Outcomes in Phase 3 Clinical Trials of Bezlotoxumab for the Prevention of Recurrent Clostridioides difficile Infection: A Post Hoc Analysis of MODIFY I/II (2019) (7)
- Serology in Patients Treated with Albendazole for Hydatid Disease (1988) (7)
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- Evaluation of the novel artus C. difficile QS-RGQ, VanR QS-RGQ and MRSA/SA QS-RGQ assays for the laboratory diagnosis of Clostridium difficile infection (CDI), and for vancomycin-resistant enterococci (VRE) and methicillin-resistant Staphylococcus aureus (MRSA) screening (2017) (5)
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- Profiling the Effects of Systemic Antibiotics for Acne, Including the Narrow-Spectrum Antibiotic Sarecycline, on the Human Gut Microbiota (2022) (5)
- Inhibitors of bacterial protein synthesis (2012) (5)
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- Preservation of gut microbiome following ridinilazole versus fidaxomicin treatment of Clostridium difficile infection (2017) (5)
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- An Outbreak of Clostridium (Clostridioides) difficile Infections within an Acute and Long-Term Care Wards Due to Moxifloxacin-Resistant PCR Ribotype 176 Genotyped as PCR Ribotype 027 by a Commercial Assay (2020) (5)
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- Aeromonas isolates . Phenotypic methods for speciating clinical (2004) (0)
- Impact of testing on Clostridioides difficile infection in hospitals across Europe: A mathematical model. (2023) (0)
- 675Outcomes of Acute Bacterial Skin and Skin Structure Infections (ABSSSI) by vancomycin dosing regimen and vancomycin trough serum concentrations in the DISCOVER Program (2014) (0)
- Cost Consequences for the NHS of Using a Two-Step Testing Method for the Detection of Clostridium difficile with a Point of Care, Polymerase Chain Reaction Test as the First Step (2020) (0)
- 'The method used to dry washed hands affects the number and type of transient and residential bacteria remaining on the skin'. (2019) (0)
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