Mark Magnuson | Academic Influence

Mark Magnuson's AcademicInfluence.com Rankings

Mark Magnuson

Biology

#10666

World Rank

#14015

Historical Rank

Genetics

#1137

World Rank

#1236

Historical Rank

biology Degrees

Download Badge

Biology

Mark Magnuson's Degrees

Bachelors Biology University of California, Berkeley
PhD Genetics Stanford University

Similar Degrees You Can Earn

Best Online Bachelor's in Biology 2026

Why Is Mark Magnuson Influential?

(Suggest an Edit or Addition)

According to Wikipedia, Mark A. Magnuson is an American biologist, currently the Louise B. McGavock Professor of Molecular Physiology and Biophysics, Medicine, and Cell and Developmental Biology at Vanderbilt University.

(See a Problem?)

Mark Magnuson's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum. (1996) (1515)
Dual Roles for Glucokinase in Glucose Homeostasis as Determined by Liver and Pancreatic β Cell-specific Gene Knock-outs Using Cre Recombinase* (1999) (1263)
Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction. (2000) (1244)
Tissue-Specific Knockout of the Insulin Receptor in Pancreatic β Cells Creates an Insulin Secretory Defect Similar to that in Type 2 Diabetes (1999) (1162)
Thiazolidinediones expand body fluid volume through PPARγ stimulation of ENaC-mediated renal salt absorption (2005) (607)
Allosteric Activators of Glucokinase: Potential Role in Diabetes Therapy (2003) (473)
Identification of Protor as a novel Rictor-binding component of mTOR complex-2. (2007) (447)
Hepatic Glucokinase Is Required for the Synergistic Action of ChREBP and SREBP-1c on Glycolytic and Lipogenic Gene Expression* (2004) (437)
Mammalian target of rapamycin protein complex 2 regulates differentiation of Th1 and Th2 cell subsets via distinct signaling pathways. (2010) (435)
Impaired insulin secretion and β-cell loss in tissue-specific knockout mice with mitochondrial diabetes (2000) (432)
Deletion of PPARγ in adipose tissues of mice protects against high fat diet-induced obesity and insulin resistance (2005) (430)
Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability. (2006) (418)
Liver-specific deletion of negative regulator Pten results in fatty liver and insulin hypersensitivity (2004) (409)
mTOR complex 2 is required for the development of prostate cancer induced by Pten loss in mice. (2009) (409)
Salt–sensitive hypertension and reduced fertility in mice lacking the prostaglandin EP2 receptor (1999) (398)
DNA excision in liver by an albumin‐Cre transgene occurs progressively with age (2000) (382)
Plasma fibronectin supports neuronal survival and reduces brain injury following transient focal cerebral ischemia but is not essential for skin-wound healing and hemostasis. (2001) (362)
Neonatal diabetes mellitus due to complete glucokinase deficiency. (2001) (342)
β-cell–specific deletion of the Igf1 receptor leads to hyperinsulinemia and glucose intolerance but does not alter β-cell mass (2002) (340)
Pancreatic beta-cell glucokinase: closing the gap between theoretical concepts and experimental realities. (1998) (328)
Dopamine Biosynthesis Is Selectively Abolished in Substantia Nigra/Ventral Tegmental Area but Not in Hypothalamic Neurons in Mice with Targeted Disruption of the Nurr1 Gene (1998) (312)
Oestrogen protects FKBP12.6 null mice from cardiac hypertrophy (2002) (302)
Identification of a sequence in the PEPCK gene that mediates a negative effect of insulin on transcription. (1990) (294)
Control of pancreatic β cell regeneration by glucose metabolism. (2011) (290)
The network of glucokinase-expressing cells in glucose homeostasis and the potential of glucokinase activators for diabetes therapy. (2006) (289)
Analysis of upstream glucokinase promoter activity in transgenic mice and identification of glucokinase in rare neuroendocrine cells in the brain and gut. (1994) (284)
Inactivation of the Hepatic Cytochrome P450 System by Conditional Deletion of Hepatic Cytochrome P450 Reductase* (2003) (277)
Transgenic mice with green fluorescent protein-labeled pancreatic β-cells (2003) (273)
Mitochondrial metabolism mediates oxidative stress and inflammation in fatty liver. (2015) (269)
Spatiotemporal patterns of multipotentiality in Ptf1a-expressing cells during pancreas organogenesis and injury-induced facultative restoration (2013) (264)
Essential role of the tyrosine kinase substrate phospholipase C-gamma1 in mammalian growth and development. (1997) (252)
Alterations in the regulation of androgen-sensitive Cyp 4a monooxygenases cause hypertension (2001) (247)
RIP-Cre Revisited, Evidence for Impairments of Pancreatic β-Cell Function* (2006) (244)
Fat Cell–Specific Ablation of Rictor in Mice Impairs Insulin-Regulated Fat Cell and Whole-Body Glucose and Lipid Metabolism (2010) (242)
MafA and MafB Regulate Genes Critical to β-Cells in a Unique Temporal Manner (2010) (241)
Impaired insulin secretion and glucose tolerance in β cell‐selective CaV1.2 Ca2+ channel null mice (2003) (241)
Cytosolic phosphoenolpyruvate carboxykinase does not solely control the rate of hepatic gluconeogenesis in the intact mouse liver. (2007) (241)
Deletion of PPARgamma in adipose tissues of mice protects against high fat diet-induced obesity and insulin resistance. (2005) (231)
Of Mice and MEN1: Insulinomas in a Conditional Mouse Knockout (2003) (229)
Nkx6.1 Controls a Gene Regulatory Network Required for Establishing and Maintaining Pancreatic Beta Cell Identity (2013) (227)
Hepatocyte-Specific Mutation Establishes Retinoid X Receptor α as a Heterodimeric Integrator of Multiple Physiological Processes in the Liver (2000) (227)
Phosphoenolpyruvate Carboxykinase Is Necessary for the Integration of Hepatic Energy Metabolism (2000) (224)
p16Ink4a-induced senescence of pancreatic beta cells enhances insulin secretion (2016) (222)
Muscle-Specific Deletion of Rictor Impairs Insulin-Stimulated Glucose Transport and Enhances Basal Glycogen Synthase Activity (2007) (221)
Sulfonylurea Receptor Type 1 Knock-out Mice Have Intact Feeding-stimulated Insulin Secretion despite Marked Impairment in Their Response to Glucose* (2002) (216)
Replacement by homologous recombination of the minK gene with lacZ reveals restriction of minK expression to the mouse cardiac conduction system. (1999) (211)
Quantitative imaging of green fluorescent protein in cultured cells: Comparison of microscopic techniques, use in fusion proteins and detection limits (1995) (204)
Tissue-specific deletion of Foxa2 in pancreatic beta cells results in hyperinsulinemic hypoglycemia. (2001) (201)
Pdx-1 and Ptf1a concurrently determine fate specification of pancreatic multipotent progenitor cells. (2008) (200)
Rat glucokinase gene: structure and regulation by insulin. (1989) (200)
Quantitative Subcellular Imaging of Glucose Metabolism within Intact Pancreatic Islets (*) (1996) (200)
Polydactyly and ectopic ZPA formation in Alx-4 mutant mice. (1997) (197)
beta-cell-specific deletion of the Igf1 receptor leads to hyperinsulinemia and glucose intolerance but does not alter beta-cell mass. (2002) (196)
Conditional Knockout of Macrophage PPARγ Increases Atherosclerosis in C57BL/6 and Low-Density Lipoprotein Receptor–Deficient Mice (2005) (190)
Analysis of the Cre‐mediated recombination driven by rat insulin promoter in embryonic and adult mouse pancreas (2000) (189)
An alternate promoter in the glucokinase gene is active in the pancreatic beta cell. (1989) (189)
Transgenic mice with green fluorescent protein-labeled pancreatic beta -cells. (2003) (186)
pdx-1 function is specifically required in embryonic beta cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasis. (2008) (182)
Sustained Neurog3 expression in hormone-expressing islet cells is required for endocrine maturation and function (2009) (171)
Ptf1a determines horizontal and amacrine cell fates during mouse retinal development (2006) (170)
Nkx2.2 repressor complex regulates islet β-cell specification and prevents β-to-α-cell reprogramming. (2011) (170)
Cell-specific roles of glucokinase in glucose homeostasis. (2001) (169)
Targeted deletion of a cis-regulatory region reveals differential gene dosage requirements for Pdx1 in foregut organ differentiation and pancreas formation. (2006) (166)
Rictor is a novel target of p70 S6 kinase-1 (2010) (164)
Early pancreatic development requires the vertebrate Suppressor of Hairless (RBPJ) in the PTF1 bHLH complex. (2007) (164)
Concordant Glucose Induction of Glucokinase, Glucose Usage, and Glucose-Stimulated Insulin Release in Pancreatic Islets Maintained in Organ Culture (1992) (161)
The second activating glucokinase mutation (A456V): implications for glucose homeostasis and diabetes therapy. (2002) (160)
Pancreas-specific Cre driver lines and considerations for their prudent use. (2013) (159)
Impaired Tricarboxylic Acid Cycle Activity in Mouse Livers Lacking Cytosolic Phosphoenolpyruvate Carboxykinase* (2004) (159)
Mutants of glucokinase cause hypoglycaemia- and hyperglycaemia syndromes and their analysis illuminates fundamental quantitative concepts of glucose homeostasis (1999) (157)
Effects of Increased Glucokinase Gene Copy Number on Glucose Homeostasis and Hepatic Glucose Metabolism* (1997) (156)
Rictor/mTORC2 Is Essential for Maintaining a Balance Between β-Cell Proliferation and Cell Size (2011) (154)
Insights into the biochemical and genetic basis of glucokinase activation from naturally occurring hypoglycemia mutations. (2003) (154)
Conditional inactivation of the TGF-beta type II receptor using Cre:Lox. (2002) (153)
Conditional inactivation of the TGF‐β type II receptor using Cre:Lox (2002) (149)
Impaired islet function in commonly used transgenic mouse lines due to human growth hormone minigene expression. (2014) (141)
Genetic rescue of Cdk4 null mice restores pancreatic β-cell proliferation but not homeostatic cell number (2003) (139)
Identification of basal and cyclic AMP regulatory elements in the promoter of the phosphoenolpyruvate carboxykinase gene (1988) (136)
Hepatocyte Nuclear Factor 3β (Foxa2) Is Dispensable for Maintaining the Differentiated State of the Adult Hepatocyte (2000) (135)
Frataxin deficiency in pancreatic islets causes diabetes due to loss of beta cell mass. (2003) (134)
Targeted Elimination of Peroxisome Proliferator-Activated Receptor γ in β Cells Leads to Abnormalities in Islet Mass without Compromising Glucose Homeostasis (2003) (134)
Nuclear Import of Hepatic Glucokinase Depends upon Glucokinase Regulatory Protein, whereas Export Is Due to a Nuclear Export Signal Sequence in Glucokinase* (1999) (134)
Striking In Vivo Phenotype of a Disease-Associated Human SCN5A Mutation Producing Minimal Changes in Vitro (2011) (133)
A nonclassical bHLH Rbpj transcription factor complex is required for specification of GABAergic neurons independent of Notch signaling. (2008) (131)
Targeted disruption of hepatic frataxin expression causes impaired mitochondrial function, decreased life span and tumor growth in mice. (2005) (130)
Selective Deletion of Pten in Pancreatic β Cells Leads to Increased Islet Mass and Resistance to STZ-Induced Diabetes (2006) (130)
The amino acid sequence of rat liver glucokinase deduced from cloned cDNA. (1989) (129)
Glucokinase Gene Structure: Functional Implications of Molecular Genetic Studies (1990) (128)
Characterization of Glucokinase Regulatory Protein-deficient Mice* (2000) (128)
Conditional Inactivation of the Men1 Gene Leads to Pancreatic and Pituitary Tumorigenesis but Does Not Affect Normal Development of These Tissues (2004) (127)
Hepatocyte Nuclear Factor-4α Is Essential for Glucose-stimulated Insulin Secretion by Pancreatic β-Cells* (2006) (127)
Ribozyme-mediated attenuation of pancreatic beta-cell glucokinase expression in transgenic mice results in impaired glucose-induced insulin secretion. (1994) (125)
Mice Lacking α-Calcitonin Gene-Related Peptide Exhibit Normal Cardiovascular Regulation and Neuromuscular Development (1999) (123)
Differential Structure of Atrial and Ventricular KATP: Atrial KATP Channels Require SUR1 (2008) (121)
EXPRESSION OF α2-ADRENERGIC RECEPTOR SUBTYPES IN THE MOUSE BRAIN: EVALUATION OF SPATIAL AND TEMPORAL INFORMATION IMPARTED BY 3 kb OF 5′ REGULATORY SEQUENCE FOR THE α2A AR-RECEPTOR GENE IN TRANSGENIC ANIMALS (1996) (119)
Multihormonal regulation of phosphoenolpyruvate carboxykinase-chloramphenicol acetyltransferase fusion genes. Insulin's effects oppose those of cAMP and dexamethasone. (1987) (114)
The MafA Transcription Factor Becomes Essential to Islet β-Cells Soon After Birth (2014) (114)
Type 2 diabetes and congenital hyperinsulinism cause DNA double-strand breaks and p53 activity in β cells. (2014) (114)
Tissue-specific, developmental, hormonal, and dietary regulation of rat phosphoenolpyruvate carboxykinase-human growth hormone fusion genes in transgenic mice (1992) (113)
Different intracellular localization of inositol 1,4,5-trisphosphate and ryanodine receptors in cardiomyocytes. (1993) (112)
p73 Is Required for Multiciliogenesis and Regulates the Foxj1-Associated Gene Network. (2016) (106)
Mechanisms by which liver-specific PEPCK knockout mice preserve euglycemia during starvation. (2003) (105)
Location and characterization of two widely separated glucocorticoid response elements in the phosphoenolpyruvate carboxykinase gene (1988) (101)
mTORC2 regulates cardiac response to stress by inhibiting MST1. (2015) (100)
Replacement of Rbpj with Rbpjl in the PTF1 complex controls the final maturation of pancreatic acinar cells. (2010) (98)
Directed differentiation of embryonic stem cells into bladder tissue. (2007) (98)
Heterogeneous expression of glucokinase among pancreatic beta cells. (1992) (98)
Insights into the Structure and Regulation of Glucokinase from a Novel Mutation (V62M), Which Causes Maturity-onset Diabetes of the Young* (2005) (97)
Regulation of phosphoenolpyruvate carboxykinase gene expression by insulin. Use of the stable transfection approach to locate an insulin responsive sequence. (1990) (96)
The histone demethylase Jmjd3 sequentially associates with the transcription factors Tbx3 and Eomes to drive endoderm differentiation (2013) (94)
Targeted inactivation of hepatocyte growth factor receptor c-met in beta-cells leads to defective insulin secretion and GLUT-2 downregulation without alteration of beta-cell mass. (2005) (93)
Hepatic energy state is regulated by glucagon receptor signaling in mice. (2009) (93)
Multiple, temporal-specific roles for HNF6 in pancreatic endocrine and ductal differentiation (2009) (91)
Dysregulation of the Norepinephrine Transporter Sustains Cortical Hypodopaminergia and Schizophrenia-Like Behaviors in Neuronal Rictor Null Mice (2010) (89)
Ectopically expressed PDX-1 in liver initiates endocrine and exocrine pancreas differentiation but causes dysmorphogenesis. (2003) (89)
Glucokinase and glycemic disease: from basics to novel therapeutics. (2004) (87)
Mammalian glucokinase. (1993) (87)
Targeted elimination of peroxisome proliferator-activated receptor gamma in beta cells leads to abnormalities in islet mass without compromising glucose homeostasis. (2003) (86)
Generation of a conditional allele of the mouse prostaglandin EP4 receptor (2004) (84)
Ghrelin Expression in the Mouse Pancreas Defines a Unique Multipotent Progenitor Population (2012) (83)
A Functional Link between Glucokinase Binding to Insulin Granules and Conformational Alterations in Response to Glucose and Insulin* (2002) (81)
Variable effects of maturity-onset-diabetes-of-youth (MODY)-associated glucokinase mutations on substrate interactions and stability of the enzyme. (1995) (79)
Rictor Phosphorylation on the Thr-1135 Site Does Not Require Mammalian Target of Rapamycin Complex 2 (2010) (75)
Insulin secretory defects and impaired islet architecture in pancreatic beta-cell-specific STAT3 knockout mice. (2004) (75)
Temporal identity transition from Purkinje cell progenitors to GABAergic interneuron progenitors in the cerebellum (2014) (74)
Mind bomb 1 is required for pancreatic β-cell formation (2012) (73)
A Gene Regulatory Network Cooperatively Controlled by Pdx1 and Sox9 Governs Lineage Allocation of Foregut Progenitor Cells. (2015) (72)
Effects of alternate RNA splicing on glucokinase isoform activities in the pancreatic islet, liver, and pituitary. (1991) (71)
Ongoing Notch signaling maintains phenotypic fidelity in the adult exocrine pancreas. (2012) (70)
Synaptotagmin 4 Regulates Pancreatic β Cell Maturation by Modulating the Ca2+ Sensitivity of Insulin Secretion Vesicles. (2018) (70)
Thyroid hormone regulation of malic enzyme synthesis. Dual tissue-specific control. (1986) (69)
Rapid translocation of hepatic glucokinase in response to intraduodenal glucose infusion and changes in plasma glucose and insulin in conscious rats. (2004) (69)
A Rictor-Myo1c Complex Participates in Dynamic Cortical Actin Events in 3T3-L1 Adipocytes (2008) (68)
Adenovirus-mediated Knockout of a Conditional Glucokinase Gene in Isolated Pancreatic Islets Reveals an Essential Role for Proximal Metabolic Coupling Events in Glucose-stimulated Insulin Secretion* (1999) (67)
Immunohistochemical localization of phosphoenolpyruvate carboxykinase in adult and developing mouse tissues. (1990) (67)
Inactivation of TGF-beta signaling in hepatocytes results in an increased proliferative response after partial hepatectomy. (2005) (66)
Loss of Myt1 function partially compromises endocrine islet cell differentiation and pancreatic physiological function in the mouse (2007) (66)
Transcriptional Maintenance of Pancreatic Acinar Identity, Differentiation, and Homeostasis by PTF1A (2016) (64)
Tissue-specific regulation of two functional malic enzyme mRNAs by triiodothyronine. (1985) (64)
Multiple elements in the upstream glucokinase promoter contribute to transcription in insulinoma cells. (1992) (64)
Tissue‐Specific regulation of glucokinase gene expression (1992) (63)
Insm1 promotes endocrine cell differentiation by modulating the expression of a network of genes that includes Neurog3 and Ripply3 (2014) (63)
Glucose regulates cyclin D2 expression in quiescent and replicating pancreatic β-cells through glycolysis and calcium channels. (2011) (61)
Glucokinase gene locus transgenic mice are resistant to the development of obesity-induced type 2 diabetes. (2001) (59)
Optical imaging of pancreatic beta cells in living mice expressing a mouse insulin I promoter‐firefly luciferase transgene (2005) (58)
Disruption of PPARγ signaling results in mouse prostatic intraepithelial neoplasia involving active autophagy (2009) (57)
Dual Lineage‐Specific Expression of Sox17 During Mouse Embryogenesis (2012) (57)
Cell-specific Expression and Regulation of a Glucokinase Gene Locus Transgene* (1997) (56)
Precommitment low-level Neurog3 expression defines a long-lived mitotic endocrine-biased progenitor pool that drives production of endocrine-committed cells (2016) (56)
BZP, a novel serum-responsive zinc finger protein that inhibits gene transcription (1994) (55)
Inactivation of TGF-β signaling in hepatocytes results in an increased proliferative response after partial hepatectomy (2005) (53)
Setd5 is essential for mammalian development and the co-transcriptional regulation of histone acetylation (2016) (53)
Structural instability of mutant beta-cell glucokinase: implications for the molecular pathogenesis of maturity-onset diabetes of the young (type-2). (1997) (53)
Molecular cloning of a cDNA sequence for rat malic enzyme. Direct evidence for induction in vivo of rat liver malic enzyme mRNA by thyroid hormone. (1983) (52)
Glucokinase and the Regulation of Blood Sugar (2004) (51)
Restitution of defective glucose-stimulated insulin release of sulfonylurea type 1 receptor knockout mice by acetylcholine. (2004) (51)
Energy Homeostasis and Gastrointestinal Endocrine Differentiation Do Not Require the Anorectic Hormone Peptide YY (2005) (50)
Generation of islet-like cells from mouse gall bladder by direct ex vivo reprogramming. (2013) (47)
Obesity and the β cell: lessons from leptin (2007) (45)
5-amino-imidazole carboxamide riboside acutely potentiates glucose-stimulated insulin secretion from mouse pancreatic islets by KATP channel-dependent and -independent pathways. (2005) (44)
Quantification of factors influencing fluorescent protein expression using RMCE to generate an allelic series in the ROSA26 locus in mice (2011) (44)
Coding nucleotide sequence of rat liver malic enzyme mRNA. (1986) (43)
Impaired glucagon secretory responses in mice lacking the type 1 sulfonylurea receptor. (2005) (42)
Thyroid Hormone Regulation of Malic Enzyme Synthesis (1986) (42)
Defining a Novel Role for the Pdx1 Transcription Factor in Islet β-Cell Maturation and Proliferation During Weaning (2017) (42)
Chronic β-Cell Depolarization Impairs β-Cell Identity by Disrupting a Network of Ca2+-Regulated Genes (2017) (41)
Gene network transitions in embryos depend upon interactions between a pioneer transcription factor and core histones (2020) (41)
Glucokinase Thermolability and Hepatic Regulatory Protein Binding Are Essential Factors for Predicting the Blood Glucose Phenotype of Missense Mutations* (2007) (37)
Cloning and characterization of the mouse glucokinase gene locus and identification of distal liver-specific DNase I hypersensitive sites. (1995) (37)
Role of Sulfonylurea Receptor Type 1 Subunits of ATP-Sensitive Potassium Channels in Myocardial Ischemia/Reperfusion Injury (2008) (36)
Pancreatic Islet-Autonomous Insulin and Smoothened-Mediated Signaling Modulate Identity Changes of Glucagon+ α-Cells (2018) (35)
Gene-altered Mice and Metabolic Flux Control* (2003) (34)
Obesity and the beta cell: lessons from leptin. (2007) (33)
BMP Antagonist Gremlin 2 Limits Inflammation After Myocardial Infarction. (2016) (33)
Sugar binding to recombinant wild-type and mutant glucokinase monitored by kinetic measurement and tryptophan fluorescence. (2008) (33)
Glucokinase as a Glucose Sensor: Past, Present and Future (2004) (31)
Generation and functional confirmation of a conditional null PPARγ allele in mice (2002) (30)
Activation of glycine and glutamate receptors increases intracellular calcium in cells derived from the endocrine pancreas. (1998) (29)
Strategies for the use of site-specific recombinases in genome engineering. (2005) (29)
Loss of Foxd3 results in decreased β-cell proliferation and glucose intolerance during pregnancy. (2011) (29)
Anks4b, a Novel Target of HNF4α Protein, Interacts with GRP78 Protein and Regulates Endoplasmic Reticulum Stress-induced Apoptosis in Pancreatic β-Cells* (2012) (28)
Pancreatic glucokinase is activated by insulin-like growth factor-I. (2007) (28)
Cholinergic regulation of fuel-induced hormone secretion and respiration of SUR1-/- mouse islets. (2006) (27)
Mitochondrial metabolism mediates oxidative stress and inflammation in fatty liver. (2016) (26)
Efficient DNA cassette exchange in mouse embryonic stem cells by staggered positive‐negative selection (2004) (25)
Insm1 promotes neurogenic proliferation in delaminated otic progenitors (2015) (25)
The Pdx1-Bound Swi/Snf Chromatin Remodeling Complex Regulates Pancreatic Progenitor Cell Proliferation and Mature Islet β-Cell Function (2019) (24)
Recombinase‐mediated cassette exchange to rapidly and efficiently generate mice with human cardiac sodium channels (2006) (24)
Activation of FoxM1 Revitalizes the Replicative Potential of Aged β-Cells in Male Mice and Enhances Insulin Secretion (2015) (23)
Crystal Structure of Human Liver Glucokinase Bound to a Small Molecule Allosteric Activator (2004) (23)
Erratum: Mitochondrial metabolism mediates oxidative stress and inflammation in fatty liver (American Society for Clinical Investigation (2015) 125:12 (4447-4462) DOI: 10.1172/JCI82204) (2016) (23)
Informatic and Functional Approaches to Identifying a Regulatory Region for the Cardiac Sodium Channel (2011) (23)
Effects of Glucose on Insulin Secretion, Glucokinase Activity, and Transgene Expression in Transgenic Mouse Islets Containing an Upstream Glucokinase Promoter-Human Growth Hormone Fusion Gene (1994) (22)
Pancreatic Inflammation Redirects Acinar to β Cell Reprogramming. (2016) (22)
Rictor/mTORC2 deficiency enhances keratinocyte stress tolerance via mitohormesis (2017) (22)
Substrate-induced Nuclear Export and Peripheral Compartmentalization of Hepatic Glucokinase Correlates with Glycogen Deposition (2001) (21)
Regulation of specific rat liver messenger ribonucleic acids by triiodothyronine. (1985) (20)
Dominant and context-specific control of endodermal organ allocation by Ptf1a (2014) (20)
Liver-Specific Reactivation of the Inactivated Hnf-1α Gene: Elimination of Liver Dysfunction To Establish a Mouse MODY3 Model (2003) (18)
iterativeWGCNA: iterative refinement to improve module detection from WGCNA co-expression networks (2017) (18)
Partial promoter substitutions generating transcriptional sentinels of diverse signaling pathways in embryonic stem cells and mice (2012) (18)
The imidazoline RX871024 stimulates insulin secretion in pancreatic beta-cells from mice deficient in K(ATP) channel function. (2001) (18)
Nkx2.2:Cre knock‐in mouse line: A novel tool for pancreas‐ and CNS‐specific gene deletion (2013) (18)
c-Myc downregulation is required for preacinar to acinar maturation and pancreatic homeostasis (2017) (17)
Glucose Regulates Microtubule Disassembly and the Dose of Insulin Secretion via Tau Phosphorylation (2020) (17)
Myeloid Cell-Derived HB-EGF Drives Tissue Recovery After Pancreatitis (2019) (17)
ROCK-nmMyoII, Notch and Neurog3 gene-dosage link epithelial morphogenesis with cell fate in the pancreatic endocrine-progenitor niche (2018) (17)
Generation of Nkx2.2:lacZ mice using recombination‐mediated cassette exchange technology (2012) (17)
Inactivation of mTORC2 in macrophages is a signature of colorectal cancer that promotes tumorigenesis. (2019) (17)
Transgene-associated human growth hormone expression in pancreatic β-cells impairs identification of sex-based gene expression differences. (2019) (17)
Effects of altered glucokinase gene copy number on blood glucose homoeostasis. (1997) (16)
A role for intronic sequences on expression of thyroid hormone receptor alpha gene. (1994) (16)
Coexpression of glucose transporters and glucokinase in Xenopus oocytes indicates that both glucose transport and phosphorylation determine glucose utilization. (1994) (16)
Forebrain Ptf1a Is Required for Sexual Differentiation of the Brain. (2018) (16)
Characterization of the Pal motifs in the upstream glucokinase promoter: binding of a cell type-specific protein complex correlates with transcriptional activation. (1996) (15)
Isolation and characterization of the mouse cytosolic phosphoenolpyruvate carboxykinase (GTP) gene: evidence for tissue-specific hypersensitive sites (1999) (15)
Notch Controls Multiple Pancreatic Cell Fate Regulators Through Direct Hes1-mediated Repression (2018) (15)
Structural characterization of the rat malic enzyme gene. (1989) (14)
Targeted oncogenesis of hormone-negative pancreatic islet progenitor cells. (1998) (13)
[Role of glucokinase (GK) in the maintenance of glucose homeostasis. Specific disruption of the gene by the Cre-loxP technique]. (1999) (13)
Induction of the glucokinase gene by insulin in cultured neonatal rat hepatocytes. Relationship with DNase-I hypersensitive sites and functional analysis of a putative insulin-response element. (1996) (13)
Hepatic glucose sensing: does flux matter? (2008) (11)
Cytosolic phosphoenolpyruvate carboxykinase as a cataplerotic pathway in the small intestine. (2018) (11)
A recombinase‐mediated cassette exchange‐derived cyan fluorescent protein reporter allele for Pdx1 (2012) (10)
Molecular pathogenesis of MODYs (2000) (10)
Insm 1 promotes endocrine cell differentiation by modulating the expression of a network of genes that includes Neurog 3 and Ripply 3 (2014) (10)
The Pal elements in the upstream glucokinase promoter exhibit dyad symmetry and display cell-specific enhancer activity when multimerised (2004) (9)
Coding nucleotide sequence of rat malic enzyme mRNA and tissue specific regulation by thyroid hormone. (1989) (9)
Transcriptional regulation by thyroid hormone of an mRNA homologous to a protease inhibitor. (1986) (9)
Glucokinase Gene Expression and Regulation (1994) (9)
Response to Comment on: Kumar et al. Fat Cell–Specific Ablation of Rictor in Mice Impairs Insulin-Regulated Fat Cell and Whole-Body Glucose and Lipid Metabolism. Diabetes 2010;59:1397–1406 (2011) (8)
Imaging beta cell development in real-time using pancreatic explants from mice with green fluorescent protein-labeled pancreatic beta cells (2007) (8)
Alpha to Beta Cell Reprogramming: Stepping toward a New Treatment for Diabetes. (2018) (8)
The mammal-specific Pdx1 Area II enhancer has multiple essential functions in early endocrine cell specification and postnatal β-cell maturation (2017) (8)
Excitotoxicity and Overnutrition Additively Impair Metabolic Function and Identity of Pancreatic β-Cells (2020) (8)
Evolutionary conservation of elements in the upstream glucokinase promoter. (1993) (7)
Liver-specific insulin receptor knockout mice are severely insulin resistant (1999) (6)
Engineering artificial signaling centers to polarize embryoid body differentiation. (2012) (6)
A developmental lineage-based gene co-expression network for mouse pancreatic β-cells reveals a role for Zfp800 in pancreas development (2021) (5)
New Complexity in Differentiating Stem Cells Toward Hepatic and Pancreatic Fates (2009) (5)
Caveats and considerations for performing pancreas‐specific gene manipulations in the mouse (2007) (5)
Nucleotide sequence of mouse SCIP cDNA, a POU-domain transcription factor. (1991) (4)
Temporal Transcriptome Analysis Reveals Dynamic Gene Expression Patterns Driving β-Cell Maturation (2021) (4)
Multi-omic analyses in Abyssinian cats with primary renal amyloid deposits (2021) (3)
FUCCI tracking shows cell‐cycle‐dependent Neurog3 variation in pancreatic progenitors (2017) (3)
Cell specific differences in DNase I hypersensitivity between the two promoters of the rat glucokinase gene. (1995) (3)
Arrhythmia / Electrophysiology Striking In Vivo Phenotype of a Disease-Associated Human SCN 5 A Mutation Producing Minimal Changes in Vitro (2011) (3)
Research resource: dkCOIN, the National Institute of Diabetes, Digestive and Kidney Diseases (NIDDK) consortium interconnectivity network: a pilot program to aggregate research resources generated by multiple research consortia. (2012) (3)
The Glucokinase System and the Regulation of Blood Sugar (2000) (3)
Variable expression of hepatic glucokinase in mice is due to a regulational locus that cosegregates with the glucokinase gene. (1997) (3)
Microtubules regulate pancreatic beta cell heterogeneity via spatiotemporal control of insulin secretion hot spots (2020) (2)
Pancreatic islet-autonomous insulin and smoothened-mediated signalling modulate identity changes of glucagon+ α-cells (2018) (2)
Role of hepatic glucokinase in the stimulatory effect of SREBP-1c on glycolytic and lipogenic gene expression (2003) (1)
Multiple elements in the upstream glucokinase promoter contribute to transcription in insulinoma cells (1992) (1)
Tissue-Specific Regulation of Glucokinase (2018) (1)
Deletion of Jazf1 gene causes early growth retardation and insulin resistance in mice. (2022) (1)
A Gene Regulatory Netwo rk Cooperatively Controlled by Pdx 1 and Sox 9 Governs Lineage Allocation of Foregut Progenitor Cells Graphical (1)
A Rictor-Myo 1 c Complex Participates in Dynamic Cortical Actin Events in 3 T 3L 1 Adipocytes ‡ (2017) (1)
Insm1, Neurod1, and Pax6 promote murine pancreatic endocrine cell development through overlapping yet distinct RNA transcription and splicing programs (2021) (1)
Dispositif de protection embolique en mousse (2006) (0)
Abstract 1431: SUR1 Knockout Mice are Protected Against Myocardial Ischemia-Reperfusion Injury (2006) (0)
- Perspectives in Diabetes Pancreatic P-Cell Glucokinase Closing the Gap Between Theoretical Concepts and Experimental Realities (2006) (0)
Genetic studies on the development and function of the hypothalamus using Ptf1a-Cre & -flox knock-in mice (2011) (0)
848 TGF-β signal pathway activation regulates restoration of quiescence in the regenerating liver and of the liver mass: body weight ratio after partial hepatectomy (2003) (0)
Cytokine-driven beta-cell production in vivo (2014) (0)
CAMSAP2 localizes to the Golgi in islet β-cells and facilitates Golgi-ER trafficking (2023) (0)
FUCCI tracking shows that Neurog3 levels vary with cell-cycle phase in endocrine-biased pancreatic progenitors (2017) (0)
BASIC—LIVER, PANCREAS, AND BILIARY TRACT Replacement of Rbpj With Rbpjl in the PTF1 Complex Controls the Final Maturation of Pancreatic Acinar Cells (2010) (0)
Cell-Specific Roles for Glucokinase in Glucose Homeostasis and the Pathogenesis of Hyperglycemia in MODY2 as Determined by Studies in Mice (2000) (0)
CAMSAP2 localizes to the Golgi apparatus in pancreatic β-cells to facilitate Golgi-endoplasmic reticulum trafficking and support robust insulin secretion (2023) (0)
SASsy and faithful tools to monitor signal transduction during differentiation (2008) (0)
4-23-2008 A Rictor-Myo 1 c complex participates in dynamic cortical actin events in 3 T 3-L 1 adipocytes (2017) (0)
The microtubule minus end-binding protein CAMSAP2 does not regulate microtubule dynamics in primary pancreatic β-cells but facilitates insulin secretion (2022) (0)
Mammalian target of rapamycin complex 2 regulates helper T cell differentiation and function (47.31) (2009) (0)
Gene network transitions in embryos depend upon interactions between a pioneer transcription factor and core histones (2020) (0)
Title Pages / Contents / Preface (2004) (0)
Cell Metabolism Glycolysis Control of b Cell Regeneration and Mass (2011) (0)
Species-specific roles for the MAFA and MAFB transcription factors in regulating islet β cell identity (2022) (0)
Title Forebrain Ptf 1 a Is Required for Sexual Differentiation of theBrain (2018) (0)
Mammalian target of rapamycin complex 2 regulates helper T cell differentiation and function (2009) (0)
Mining the 99 Lives Cat Genome Sequencing Consortium database implicates genes and variants for the Ticked locus in domestic cats ( Felis catus ) (2021) (0)
Differential regulation of alternate promoter regions in Sox17 during endodermal and vascular endothelial development (2022) (0)
Commonly used pancreatic Cre-driver lines secrete human growth hormone which profoundly alters islet phenotype (2014) (0)
A method for inserting a medical device into a delivery system (2007) (0)
mTORC2 in T Lymphocyte Development and Proliferation (2008) (0)
Single-cell RNA sequencing of Sox17-expressing lineages reveals distinct gene regulatory networks and dynamic developmental trajectories. (2023) (0)
Use of a Cre/Loxp Strategy in Mice to Determine the Cell-Specific Roles of Glucokinase in Mody-2 (2001) (0)
mTORC 2 Regulates Cardia c Response to Stress by Inhibiting MST 1 Graphical Abstract Highlights (2015) (0)
First genome-wide CNV mapping in FELIS CATUS using next generation sequencing data (2018) (0)
Franz Matschinsky, MD (1931–2022): Paragon of Scientific Rigor and Curiosity Who Discovered Glucokinase as the Pancreatic Glucose Sensor (2022) (0)

This paper list is powered by the following services:

Other Resources About Mark Magnuson

en.wikipedia.org

What Schools Are Affiliated With Mark Magnuson?

Mark Magnuson is affiliated with the following schools: