Mark Peeples
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Pediatrics researcher
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Philosophy
Mark Peeples's Degrees
- PhD Pediatrics Stanford University
- Doctorate Medicine University of California, San Francisco
Why Is Mark Peeples Influential?
(Suggest an Edit or Addition)According to Wikipedia, Mark E. Peeples is an American biologist, focusing on protein structure and folding, and the molecular basis of disease and virology. He is doing research on RSV infection. He is currently at The Research Institute at Nationwide Children's Hospital and Ohio State University and is an Elected Fellow of the American Association for the Advancement of Science.
Mark Peeples's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Respiratory Syncytial Virus Infection of Human Airway Epithelial Cells Is Polarized, Specific to Ciliated Cells, and without Obvious Cytopathology (2002) (519)
- Glycosaminoglycan Sulfation Requirements for Respiratory Syncytial Virus Infection (2000) (294)
- Prefusion F–specific antibodies determine the magnitude of RSV neutralizing activity in human sera (2015) (275)
- Infection of Ciliated Cells by Human Parainfluenza Virus Type 3 in an In Vitro Model of Human Airway Epithelium (2005) (266)
- Functional Analysis of Recombinant Respiratory Syncytial Virus Deletion Mutants Lacking the Small Hydrophobic and/or Attachment Glycoprotein Gene (2001) (262)
- Role of virion-associated glycosylphosphatidylinositol-linked proteins CD55 and CD59 in complement resistance of cell line-derived and primary isolates of HIV-1 (1995) (255)
- Iduronic acid-containing glycosaminoglycans on target cells are required for efficient respiratory syncytial virus infection. (2000) (239)
- Newcastle disease virus selectively kills human tumor cells. (1992) (235)
- Structure and function of respiratory syncytial virus surface glycoproteins. (2013) (213)
- Respiratory Syncytial Virus Uses CX3CR1 as a Receptor on Primary Human Airway Epithelial Cultures (2015) (187)
- Differential response of dendritic cells to human metapneumovirus and respiratory syncytial virus. (2006) (178)
- Newcastle disease virus therapy of human tumor xenografts: antitumor effects of local or systemic administration. (2001) (173)
- Plasticity and Virus Specificity of the Airway Epithelial Cell Immune Response during Respiratory Virus Infection (2012) (172)
- Complete regression of human fibrosarcoma xenografts after local Newcastle disease virus therapy. (1994) (161)
- Requirements for the Assembly and Release of Newcastle Disease Virus-Like Particles (2006) (158)
- Human liver plasma membranes contain receptors for the hepatitis B virus pre-S1 region and, via polymerized human serum albumin, for the pre-S2 region (1989) (143)
- Respiratory syncytial virus stimulates neutrophil degranulation and chemokine release. (1999) (132)
- Complete regression of human neuroblastoma xenografts in athymic mice after local Newcastle disease virus therapy. (1994) (129)
- The attachment function of the Newcastle disease virus hemagglutinin-neuraminidase protein can be separated from fusion promotion by mutation. (1993) (127)
- Respiratory syncytial virus with the fusion protein as its only viral glycoprotein is less dependent on cellular glycosaminoglycans for attachment than complete virus. (2002) (126)
- N6-methyladenosine modification enables viral RNA to escape recognition by RNA sensor RIG-I (2019) (122)
- Increased expression of the N protein of respiratory syncytial virus stimulates minigenome replication but does not alter the balance between the synthesis of mRNA and antigenome. (1997) (113)
- RhoA Signaling Is Required for Respiratory Syncytial Virus-Induced Syncytium Formation and Filamentous Virion Morphology (2005) (111)
- The NS1 Protein of Human Respiratory Syncytial Virus Is a Potent Inhibitor of Minigenome Transcription and RNA Replication (1998) (107)
- Molecular mechanism of respiratory syncytial virus fusion inhibitors. (2016) (106)
- Respiratory Syncytial Virus Grown in Vero Cells Contains a Truncated Attachment Protein That Alters Its Infectivity and Dependence on Glycosaminoglycans (2009) (94)
- Hepatitis B virus surface antigen binds to apolipoprotein H (1994) (92)
- Respiratory syncytial virus polypeptides: their location in the virion. (1979) (84)
- Integrity of Membrane Lipid Rafts Is Necessary for the Ordered Assembly and Release of Infectious Newcastle Disease Virus Particles (2006) (82)
- Prefusion F, Postfusion F, G Antibodies, and Disease Severity in Infants and Young Children With Acute Respiratory Syncytial Virus Infection (2017) (80)
- Nuclear entry and nucleolar localization of the Newcastle disease virus (NDV) matrix protein occur early in infection and do not require other NDV proteins (1992) (76)
- Mapping the Transcription and Replication Promoters of Respiratory Syncytial Virus (2002) (74)
- Respiratory syncytial virus‐induced dysregulation of expression of a mucosal β‐defensin augments colonization of the upper airway by non‐typeable Haemophilus influenzae (2009) (71)
- Nucleotide sequence and expression of the human gene encoding apolipoprotein H (β2-glycoprotein I) (1991) (69)
- The matrix protein of Newcastle disease virus localizes to the nucleus via a bipartite nuclear localization signal. (1993) (67)
- RhoA is activated during respiratory syncytial virus infection. (2001) (66)
- Respiratory Syncytial Virus Genotypes, Host Immune Profiles, and Disease Severity in Young Children Hospitalized With Bronchiolitis (2017) (66)
- Determination of the henipavirus phosphoprotein gene mRNA editing frequencies and detection of the C, V and W proteins of Nipah virus in virus-infected cells. (2009) (63)
- Paramyxovirus M Proteins (1991) (63)
- Soluble Respiratory Syncytial Virus Fusion Protein in the Fully Cleaved, Pretriggered State Is Triggered by Exposure to Low-Molarity Buffer (2011) (60)
- Cholesterol-Rich Microdomains as Docking Platforms for Respiratory Syncytial Virus in Normal Human Bronchial Epithelial Cells (2011) (59)
- Functional Analysis of the Genomic and Antigenomic Promoters of Human Respiratory Syncytial Virus (2000) (58)
- Mutations in the 5′ Trailer Region of a Respiratory Syncytial Virus Minigenome Which Limit RNA Replication to One Step (2000) (57)
- A Zika virus vaccine expressing premembrane-envelope-NS1 polyprotein (2018) (57)
- SARS-CoV-2 Spreads through Cell-to-Cell Transmission (2021) (55)
- SARS-CoV-2 spreads through cell-to-cell transmission (2021) (50)
- Interaction between respiratory syncytial virus and glycosaminoglycans, including heparan sulfate. (2007) (49)
- Replication of Respiratory Syncytial Virus Is Inhibited by the Host Defense Molecule Viperin (2012) (48)
- Influenza hemagglutinin-mediated fusion pores connecting cells to planar membranes: flickering to final expansion (1993) (46)
- Mutation in the matrix protein of Newcastle disease virus can result in decreased fusion glycoprotein incorporation into particles and decreased infectivity (1984) (46)
- Conformational change in a viral glycoprotein during maturation due to disulfide bond disruption. (1987) (45)
- A safe and highly efficacious measles virus-based vaccine expressing SARS-CoV-2 stabilized prefusion spike (2021) (43)
- Distinct and Overlapping Roles of Nipah Virus P Gene Products in Modulating the Human Endothelial Cell Antiviral Response (2012) (42)
- ERK‐1/2 activity is required for efficient RSV infection (2004) (42)
- Roles of the Putative Integrin-Binding Motif of the Human Metapneumovirus Fusion (F) Protein in Cell-Cell Fusion, Viral Infectivity, and Pathogenesis (2014) (42)
- Synergistic effects of gene-end signal mutations and the M2-1 protein on transcription termination by respiratory syncytial virus. (2001) (41)
- Differential detergent treatment allows immunofluorescent localization of the Newcastle disease virus matrix protein within the nucleus of infected cells. (1988) (41)
- Viral N6-methyladenosine upregulates replication and pathogenesis of human respiratory syncytial virus (2019) (41)
- Completion of trimeric hairpin formation of influenza virus hemagglutinin promotes fusion pore opening and enlargement. (2003) (39)
- Aetiology of influenza-like illness in adults includes parainfluenzavirus type 4. (2009) (39)
- Development and clinical applications of novel antibodies for prevention and treatment of respiratory syncytial virus infection. (2017) (39)
- Association of soluble matrix protein of Newcastle disease virus with liposomes is independent of ionic conditions. (1988) (37)
- Cranial nerve involvement with Lyme borreliosis demonstrated by magnetic resonance imaging (1992) (36)
- Neuraminidase treatment of respiratory syncytial virus-infected cells or virions, but not target cells, enhances cell-cell fusion and infection. (2003) (35)
- Targeting RSV with vaccines and small molecule drugs. (2012) (33)
- A Respiratory Syncytial Virus Replicon That Is Noncytotoxic and Capable of Long-Term Foreign Gene Expression (2011) (33)
- Immune profiles provide insights into respiratory syncytial virus disease severity in young children (2020) (31)
- Intracellular processing of the paramyxovirus F protein: critical role of the predicted amphipathic alpha helix adjacent to the fusion domain (1992) (31)
- Strain variation and nuclear association of Newcastle disease virus matrix protein (1988) (31)
- Respiratory Syncytial Virus Engineered To Express the Cystic Fibrosis Transmembrane Conductance Regulator Corrects the Bioelectric Phenotype of Human Cystic Fibrosis Airway Epithelium In Vitro (2010) (29)
- Isolation and characterization of Borrelia burgdorferi from Illinois Ixodes dammini (1991) (28)
- An altered form of apolipoprotein H binds hepatitis B virus surface antigen most efficiently. (1996) (27)
- The Journey to an RSV Vaccine. (2020) (26)
- Acute, posterior, multifocal, placoid, pigment epitheliopathy and Lyme disease. (1992) (25)
- Respiratory Syncytial Virus Infection Reduces β2-Adrenergic Responses in Human Airway Smooth Muscle (2006) (24)
- Protein Kinase C-α Activity Is Required for Respiratory Syncytial Virus Fusion to Human Bronchial Epithelial Cells (2004) (24)
- The journey to a respiratory syncytial virus vaccine (2020) (23)
- Severe SARS-CoV-2 disease in the context of a NF-κB2 loss-of-function pathogenic variant (2020) (22)
- UV irradiation analysis of complementation between, and replication of, RNA-negative temperature-sensitive mutants of Newcastle disease virus (1982) (21)
- Newcastle Disease Virus Replication (1988) (19)
- Cell culture assay system for the evaluation of natural product-mediated anti-Hepatitis B virus activity. (1997) (19)
- Characterization and Acute-Phase Modulation of Canine Apolipoprotein H (β2-Glycoprotein 1) (1993) (18)
- Nucleotide sequence and expression of the human gene encoding apolipoprotein H (beta 2-glycoprotein I). (1991) (18)
- Retinoic acid enhances killing of neuroblastoma cells by Newcastle disease virus. (1993) (17)
- Detection and quantitation of human respiratory syncytial virus (RSV) using minigenome cDNA and a Sindbis virus replicon: a prototype assay for negative-strand RNA viruses. (1998) (17)
- Effect of respiratory syncytial virus infection of HeLa-cell macromolecular synthesis. (1977) (17)
- A cultured cell receptor for the small S protein of hepatitis B virus. (1987) (16)
- The Vero cell receptor for the hepatitis B virus small S protein is a sialoglycoprotein. (1988) (16)
- Nonsegmented Negative-Sense RNA Viruses Utilize N6-Methyladenosine (m6A) as a Common Strategy To Evade Host Innate Immunity (2021) (15)
- Mathematical modelling identifies the role of adaptive immunity as a key controller of respiratory syncytial virus in cotton rats (2019) (15)
- Respiratory syncytial virus infection reduces beta2-adrenergic responses in human airway smooth muscle. (2006) (14)
- Protein kinase C-alpha activity is required for respiratory syncytial virus fusion to human bronchial epithelial cells. (2004) (13)
- Characterization and acute phase modulation of canine apolipoprotein H (beta 2-glycoprotein I). (1993) (13)
- Virion functions of RNA+ temperature-sensitive mutants of Newcastle disease virus (1982) (13)
- Caspase-4/11 exacerbates disease severity in SARS–CoV-2 infection by promoting inflammation and immunothrombosis (2021) (13)
- Structure and Function of RSV Surface Glycoproteins (2014) (13)
- Respiratory Syncytial Virus Vaccines: Are We Making Progress? (2019) (13)
- Mapping the anatomy of respiratory syncytial virus infection of the upper airways in chinchillas (Chinchilla lanigera). (2010) (12)
- Preventing Cleavage of the Respiratory Syncytial Virus Attachment Protein in Vero Cells Rescues the Infectivity of Progeny Virus for Primary Human Airway Cultures (2015) (11)
- The larger attachment glycoprotein of respiratory syncytial virus produced in primary human bronchial epithelial cultures reduces infectivity for cell lines (2021) (11)
- A Methyltransferase-Defective Vesicular Stomatitis Virus-Based SARS-CoV-2 Vaccine Candidate Provides Complete Protection against SARS-CoV-2 Infection in Hamsters (2021) (10)
- Five Residues in the Apical Loop of the Respiratory Syncytial Virus Fusion Protein F2 Subunit Are Critical for Its Fusion Activity (2018) (10)
- Metabolic requirements for the maturation of respiratory syncytial virus. (1980) (10)
- A viral-vectored RSV vaccine induces long-lived humoral immunity in cotton rats. (2018) (10)
- Efficient method for site-directed mutagenesis in large plasmids without subcloning (2017) (10)
- RNA synthesis by Newcastle disease virus temperature-sensitive mutants in two RNA-negative complementation groups (1982) (9)
- In vitro 3D culture lung model from expanded primary cystic fibrosis human airway cells. (2020) (9)
- Respiratory Syncytial Virus (RSV)–Specific Antibodies in Pregnant Women and Subsequent Risk of RSV Hospitalization in Young Infants (2021) (8)
- Discovery of Sisunatovir (RV521), an Inhibitor of Respiratory Syncytial Virus Fusion. (2021) (8)
- Temperature-sensitive mutants of Newcastle disease virus altered in HN glycoprotein size, stability, or antigenic maturity. (1988) (7)
- Interferon-induced transmembrane protein 3 (IFITM3) limits lethality of SARS-CoV-2 in mice (2021) (7)
- Viral RNA N6-methyladenosine modification modulates both innate and adaptive immune responses of human respiratory syncytial virus (2021) (7)
- Evolution of Vaccinia Virus-Specific CD8+ Cytotoxic T-Lymphocyte Responses in Primary Vaccinees and Revaccinees (2004) (7)
- CX3CR1 Is a Receptor for Human Respiratory Syncytial Virus in Cotton Rats (2021) (7)
- SARS-CoV-2 prefusion spike protein stabilized by six rather than two prolines is more potent for inducing antibodies that neutralize viral variants of concern (2022) (7)
- Thermostabilities of Virion Activities of Newcastle Disease Virus: Evidence that the Temperature-Sensitive Mutants in Complementation Groups B, BC, and C Have Altered HN Proteins (1983) (7)
- Vesicular Stomatitis Virus and DNA Vaccines Expressing Zika Virus Nonstructural Protein 1 Induce Substantial but Not Sterilizing Protection against Zika Virus Infection (2020) (6)
- Post-viral atopic airway disease: pathogenesis and potential avenues for intervention (2018) (6)
- Characteristics of a persistent respiratory syncytial virus infection in HeLa cells. (1981) (5)
- Interstitial Lung Disease in a Child with Antisynthetase Syndrome (2013) (5)
- Kinetics of virus-induced hemolysis measured for single erythrocytes. (1990) (5)
- The psychoactive substance of cannabis Δ9-tetrahydrocannabinol (THC) negatively regulates CFTR in airway cells. (2018) (5)
- Detection of antibodies in late Lyme disease. (1990) (5)
- Physiology and function of the vero cell receptor for the hepatitis B virus small S protein. (1990) (5)
- Stable Attenuation of Human Respiratory Syncytial Virus for Live Vaccines by Deletion and Insertion of Amino Acids in the Hinge Region between the mRNA Capping and Methyltransferase Domains of the Large Polymerase Protein (2020) (4)
- Live Attenuated Vaccine with a Stabilized Mutation and Gene Deletion for Prevention of Respiratory Syncytial Virus Disease in Young Children. (2019) (4)
- A ts mutant of newcastle disease virus that is defective in Fo cleavage and in antibody binding under nonpermissive conditions (1985) (4)
- 489 Respiratory syncytial virus-induced release of RANTES and MIP-1α by bronchial epithelial and peripheral mononuclear cells (1996) (4)
- A highly efficacious live attenuated mumps virus–based SARS-CoV-2 vaccine candidate expressing a six-proline stabilized prefusion spike (2022) (4)
- Immunogenicity and inflammatory properties of respiratory syncytial virus attachment G protein in cotton rats (2021) (3)
- Advanced Live Attenuated Vaccines for the Prevention of Respiratory Syncytial Virus Infections in Young Children. (2019) (3)
- Importance of Virus Characteristics in Respiratory Syncytial Virus-Induced Disease. (2019) (3)
- Mucosal Delivery of Recombinant Vesicular Stomatitis Virus Vectors Expressing Envelope Proteins of Respiratory Syncytial Virus Induces Protective Immunity in Cotton Rats (2021) (3)
- Type-III Interferons, Viral Loads, Age, and Disease Severity in Young Children with Respiratory Syncytial Virus Infection. (2022) (3)
- Next-generation RSV vaccines avoid flipping out (2022) (2)
- The hepatitis B virus receptor: Book'em, Dano? (1994) (2)
- 5-methylcytosine (m5C) RNA modification controls the innate immune response to virus infection by regulating type I interferons (2022) (2)
- Mathematical Modeling Identifies the Role of Adaptive Immunity as a Key Controller of Respiratory Syncytial Virus (RSV) Titer in Cotton Rats (2018) (1)
- Atopic Neutrophils Prevent Postviral Airway Disease (2021) (1)
- Intracellular maturation of the Newcastle disease virus fusion protein is affected by strain differences in the predicted amphipathic alpha-helix adjacent to the fusion domain. (1995) (1)
- A Novel Live Attenuated Respiratory Syncytial Virus Vaccine Candidate with Mutations in the L Protein SAM Binding Site and the G Protein Cleavage Site Is Protective in Cotton Rats and a Rhesus Macaque (2020) (1)
- Severe Acute Respiratory Syndrome Coronavirus 2 RNAemia and Clinical Outcomes in Children With Coronavirus Disease 2019 (2021) (1)
- Interferon‐induced transmembrane protein 3 (IFITM3) limits lethality of SARS‐CoV‐2 in mice (2023) (1)
- Erratum: Differential response of dendritic cells to human metapneumovirus and respiratory syncytial virus (American Journal of Respiratory Cell and Molecular Biology (March 2006) 34 (320-329)) (2006) (1)
- Upregulation of CD32 in T Cells from Infants with Severe Respiratory Syncytial Virus Disease: A New Costimulatory Pathway? (2020) (1)
- RESPONSE DURING RESPIRATORY VIRAL INFECTION (2012) (1)
- 131. The Protective Role of Mucosal Interferons in Infants with Respiratory Syncytial Virus (RSV) Infection (2020) (1)
- MAPPING MUTANT AND WILD-TYPE M PROTEINS OF NEWCASTLE DISEASE VIRUS (NDV) BY REPEATED PARTIAL PROTEOLYSIS1 (1984) (1)
- This information is current as Release Neutrophil Degranulation and Chemokine Respiratory Syncytial Virus Stimulates (1999) (0)
- Synchronization Temperature Determines the Location of RSV Fusion During Entry in Cultured Cells (2021) (0)
- Prime-pull immunization of mice with a BcfA-adjuvanted vaccine elicits mucosal immunity and prevents SARS CoV-2 infection and pathology (2022) (0)
- Architecture and matrix assembly determinants of Bordetella pertussis biofilms on primary human airway epithelium (2023) (0)
- HumanLiverPlasmaMembranes Contain Receptors forthe Hepatitis B VirusPre-Si Region and,viaPolymerized HumanSerumAlbumin, forthePre-S2 Region (1989) (0)
- The newcastle disease virus fusion glycoprotein is a noncovalent multimer which is disrupted and loses antigenicity upon boiling (1988) (0)
- Prime-Pull Immunization of Mice with a BcfA-Adjuvanted Vaccine Elicits Sustained Mucosal Immunity That Prevents SARS-CoV-2 Infection and Pathology. (2023) (0)
- Respiratory Syncytial Virus (Pneumoviridae) (2021) (0)
- A Zika virus vaccine expressing premembrane-envelope-NS1 polyprotein (2018) (0)
- Supplementary material from "Mathematical modelling identifies the role of adaptive immunity as a key controller of respiratory syncytial virus in cotton rats" (2019) (0)
- Levalbuterol increases IL-4 and IL-5 and decreases IFN-gamma release from respiratory syncytial virus (RSV)-stimulated peripheral blood mononuclear cells (PBMCs) (2005) (0)
- Albuterol preferentially increases IL-4 over IFN-γ release from respiratory syncytial virus-stimulated peripheral blood mononuclear cells (2004) (0)
- Detection de virus a arn negatif (1999) (0)
- Short Communication Determination of the henipavirus phosphoprotein gene mRNA editing frequencies and detection of the C, V and W proteins of Nipah virus in virus- infected cells (2009) (0)
- Novel non-segmented negative-sense RNA virus-based vaccine platforms for Zika virus (2020) (0)
- Requirements for the Assembly and Release of Newcastle Disease Virus-Like Particles (2007) (0)
- 79. Mucosal Interferon (IFN) Responses in Infants with Respiratory Syncytial Virus (RSV) Infection to Inform Live Attenuated Vaccine (LAV) Development (2019) (0)
- SARS-CoV-2 RNAemia and clinical outcomes in children with COVID-19. (2021) (0)
- Replicon de virus a arn de polarite negative (2004) (0)
- CRIMEAN-CONGO HEMORRHAGIC FEVER VIRUS ENTRY INTO HOST CELLS OCCURS THROUGH THE MULTIVESICULAR BODY AND REQUIRES ESCRT REGULATORS (2015) (0)
- Robust Control for Linear Stages in Electronic Manufacturing (2007) (0)
- Nirsevimab-resistant respiratory syncytial virus strains are rare but there. (2023) (0)
- Influenza A virus modulates ACE2 expression and SARS-CoV-2 infectivity in human cardiomyocytes (2022) (0)
- B . 5 Using Selective Reaction Monitoring ( SRM ) Mass Spectrometry To Unmask Regulatory Feedback Loops Controlling Adipogenesis (2014) (0)
- Recombinant measles virus expressing prefusion spike protein stabilized by six rather than two prolines is more efficacious against SARS‐CoV‐2 infection (2023) (0)
- 1193. Mucosal Antibody Responses to Respiratory Syncytial Virus (RSV) in Infants and Young Children (2021) (0)
- High-Throughput Bioprinting of the Nasal Epithelium using Patient-derived Nasal Epithelial Cells (2023) (0)
- Human Stem Cell Models of SARS-CoV-2 Infection in the Cardiovascular System (2021) (0)
- Correction to: Human Stem Cell Models of SARS‑CoV‑2 Infection in the Cardiovascular System (2021) (0)
- Inhibition of respiratory syncytial virus replication by vector-derived small interfering RNAs against NS1 protein (2004) (0)
- Cholesterol-Rich Microdomains as Docking Platforms for Respiratory Syncytial Virus in Normal Human Bronchial Epithelial Cells (2012) (0)
- Human Stem Cell Models of SARS-CoV-2 Infection in the Cardiovascular System (2021) (0)
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Mark Peeples is affiliated with the following schools:
