Markus Stoffel
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Diabetes researcher
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Philosophy
Markus Stoffel's Degrees
- PhD Biomedical Sciences University of California, San Francisco
- Masters Biochemistry University of California, Berkeley
- Bachelors Biology University of California, Berkeley
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(Suggest an Edit or Addition)Markus Stoffel's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Combinatorial microRNA target predictions (2005) (4715)
- Silencing of microRNAs in vivo with ‘antagomirs’ (2005) (3953)
- A pancreatic islet-specific microRNA regulates insulin secretion (2004) (2061)
- Leptin activation of Stat3 in the hypothalamus of wild–type and ob/ob mice but not db/db mice (1996) (1106)
- Mutations in the hepatocyte nuclear factor-4α gene in maturity-onset diabetes of the young (MODY1) (1996) (994)
- MicroRNAs 103 and 107 regulate insulin sensitivity (2011) (904)
- Mechanisms and optimization of in vivo delivery of lipophilic siRNAs (2007) (852)
- A skin microRNA promotes differentiation by repressing ‘stemness’ (2008) (783)
- Familial hyperglycemia due to mutations in glucokinase. Definition of a subtype of diabetes mellitus. (1993) (779)
- G Protein-Coupled Inwardly Rectifying K+ Channels (GIRKs) Mediate Postsynaptic but Not Presynaptic Transmitter Actions in Hippocampal Neurons (1997) (728)
- miR-375 maintains normal pancreatic α- and β-cell mass (2009) (697)
- Nonsense mutation in the glucokinase gene causes early-onset non-insulin-dependent diabetes mellitus (1992) (617)
- Assessing the ceRNA hypothesis with quantitative measurements of miRNA and target abundance. (2014) (563)
- A Family with Severe Insulin Resistance and Diabetes Due to a Mutation in AKT2 (2004) (555)
- Specificity, duplex degradation and subcellular localization of antagomirs (2007) (457)
- Hepatocyte nuclear factor-1α is an essential regulator of bile acid and plasma cholesterol metabolism (2001) (426)
- Whole population, genome-wide mapping of hidden relatedness. (2009) (426)
- Foxa2 regulates lipid metabolism and ketogenesis in the liver during fasting and in diabetes (2004) (404)
- The maturity-onset diabetes of the young (MODY1) transcription factor HNF4alpha regulates expression of genes required for glucose transport and metabolism. (1997) (374)
- MicroRNAs: a new class of regulatory genes affecting metabolism. (2006) (371)
- Bi-directional effects of GABAB receptor agonists on the mesolimbic dopamine system (2004) (359)
- β-cell–specific deletion of the Igf1 receptor leads to hyperinsulinemia and glucose intolerance but does not alter β-cell mass (2002) (340)
- Normal cerebellar development but susceptibility to seizures in mice lacking G protein-coupled, inwardly rectifying K+ channel GIRK2. (1997) (340)
- Regulation of a transcription factor network required for differentiation and metabolism. (1998) (330)
- Insulin secretory abnormalities in subjects with hyperglycemia due to glucokinase mutations. (1994) (303)
- Obesity-induced overexpression of miR-802 impairs glucose metabolism through silencing of Hnf1b (2013) (292)
- Apolipoprotein M is required for preβ-HDL formation and cholesterol efflux to HDL and protects against atherosclerosis (2005) (281)
- Miravirsen (SPC3649) can inhibit the biogenesis of miR-122 (2013) (278)
- Impact of MicroRNA Levels, Target-Site Complementarity, and Cooperativity on Competing Endogenous RNA-Regulated Gene Expression (2016) (262)
- Insulin receptors in β-cells are critical for islet compensatory growth response to insulin resistance (2007) (256)
- Strategies to determine the biological function of microRNAs (2006) (245)
- MyomiR-133 regulates brown fat differentiation through Prdm16 (2012) (241)
- Loss of HNF-1alpha function in mice leads to abnormal expression of genes involved in pancreatic islet development and metabolism. (2001) (234)
- DGCR8-dependent microRNA biogenesis is essential for skin development (2009) (231)
- Endothelin-B receptor activation triggers an endogenous analgesic cascade at sites of peripheral injury (2003) (226)
- Human glucokinase gene: isolation, characterization, and identification of two missense mutations linked to early-onset non-insulin-dependent (type 2) diabetes mellitus. (1992) (220)
- MicroRNA-7a regulates pancreatic β cell function. (2014) (217)
- Glucokinase mutations associated with non-insulin-dependent (type 2) diabetes mellitus have decreased enzymatic activity: implications for structure/function relationships. (1993) (211)
- The microRNA-200 family regulates pancreatic beta cell survival in type 2 diabetes (2015) (209)
- Insulin regulates the activity of forkhead transcription factor Hnf-3β/Foxa-2 by Akt-mediated phosphorylation and nuclear/cytosolic localization (2003) (207)
- Contribution of GIRK2-mediated postsynaptic signaling to opiate and α2-adrenergic analgesia and analgesic sex differences (2002) (205)
- Evolution of β-Cell Dysfunction in the Male Zucker Diabetic Fatty Rat (1995) (202)
- beta-cell-specific deletion of the Igf1 receptor leads to hyperinsulinemia and glucose intolerance but does not alter beta-cell mass. (2002) (196)
- Absence of Mutations in the Human OB Gene in Obese/Diabetic Subjects (1996) (189)
- microRNAs and the regulation of glucose and lipid metabolism (2007) (187)
- Forkhead box A1 regulates prostate ductal morphogenesis and promotes epithelial cell maturation (2005) (186)
- Structure and function of ASP, the human homolog of the mouse agouti gene. (1995) (186)
- G-Protein-Gated Potassium Channels Containing Kir3.2 and Kir3.3 Subunits Mediate the Acute Inhibitory Effects of Opioids on Locus Ceruleus Neurons (2002) (184)
- Coactivation of Foxa2 through Pgc-1beta promotes liver fatty acid oxidation and triglyceride/VLDL secretion. (2006) (164)
- Effective RNAi-mediated gene silencing without interruption of the endogenous microRNA pathway (2007) (163)
- A pervasive mechanism for analgesia: Activation of GIRK2 channels (2002) (158)
- Reduced β-cell mass and altered glucose sensing impair insulin-secretory function in βIRKO mice (2004) (158)
- Genotype/phenotype relationships in HNF-4alpha/MODY1: haploinsufficiency is associated with reduced apolipoprotein (AII), apolipoprotein (CIII), lipoprotein(a), and triglyceride levels. (2000) (148)
- Common SNPs in HMGCR in Micronesians and Whites Associated With LDL-Cholesterol Levels Affect Alternative Splicing of Exon13 (2008) (140)
- Altered Insulin Secretory Responses to Glucose in Subjects with a Mutation in the MODY1 Gene on Chromosome 20 (1995) (138)
- Tmem27: a cleaved and shed plasma membrane protein that stimulates pancreatic beta cell proliferation. (2005) (136)
- Missense glucokinase mutation in maturity–onset diabetes of the young and mutation screening in late–onset diabetes (1992) (136)
- Impaired glucose homeostasis and neonatal mortality in hepatocyte nuclear factor 3alpha-deficient mice. (1999) (135)
- Pancreatic beta cell-specific transcription of the pdx-1 gene. The role of conserved upstream control regions and their hepatic nuclear factor 3beta sites. (2000) (135)
- Spinal G-Protein-Gated K+ Channels Formed by GIRK1 and GIRK2 Subunits Modulate Thermal Nociception and Contribute to Morphine Analgesia (2004) (133)
- Regulation of apolipoprotein M gene expression by MODY3 gene hepatocyte nuclear factor-1alpha: haploinsufficiency is associated with reduced serum apolipoprotein M levels. (2003) (130)
- Evolution of beta-cell dysfunction in the male Zucker diabetic fatty rat. (1995) (129)
- Role of Foxa-2 in adipocyte metabolism and differentiation. (2003) (127)
- Uptake and Function Studies of Maternal Milk-derived MicroRNAs* (2015) (123)
- Defective gamma-aminobutyric acid type B receptor-activated inwardly rectifying K+ currents in cerebellar granule cells isolated from weaver and Girk2 null mutant mice. (1997) (117)
- Genome-Wide Association Studies in an Isolated Founder Population from the Pacific Island of Kosrae (2009) (117)
- Reduced beta-cell mass and altered glucose sensing impair insulin-secretory function in betaIRKO mice. (2004) (114)
- Potassium channels as targets for ethanol: studies of G-protein-coupled inwardly rectifying potassium channel 2 (GIRK2) null mutant mice. (2001) (114)
- In vivo adenine base editing of PCSK9 in macaques reduces LDL cholesterol levels (2021) (112)
- Bace2 is a β cell-enriched protease that regulates pancreatic β cell function and mass. (2011) (112)
- Identification of Glucokinase Mutations in Subjects With Gestational Diabetes Mellitus (1993) (110)
- MicroRNAs as stress regulators in pancreatic beta cells and diabetes (2017) (103)
- miR-375 gene dosage in pancreatic β-cells: implications for regulation of β-cell mass and biomarker development (2015) (100)
- Profound defects in pancreatic β-cell function in mice with combined heterozygous mutations in Pdx-1, Hnf-1α, and Hnf-3β (2002) (94)
- Plasma levels of sphingosine-1-phosphate and apolipoprotein M in patients with monogenic disorders of HDL metabolism. (2011) (90)
- The gene for erythropoietin receptor is expressed in multipotential hematopoietic and embryonal stem cells: evidence for differentiation stage-specific regulation (1992) (86)
- Epidemiology and Factor Analysis of Obesity, Type II Diabetes, Hypertension, and Dyslipidemia (Syndrome X) on the Island of Kosrae, Federated States of Micronesia (2000) (86)
- Glucagon-induced acetylation of Foxa2 regulates hepatic lipid metabolism. (2013) (85)
- Genetic dissection of the miR-200–Zeb1 axis reveals its importance in tumor differentiation and invasion (2018) (84)
- Islet secretory defect in insulin receptor substrate 1 null mice is linked with reduced calcium signaling and expression of sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA)-2b and -3. (2004) (83)
- Linkage analysis of quantitative traits for obesity, diabetes, hypertension, and dyslipidemia on the island of Kosrae, Federated States of Micronesia. (2006) (80)
- Genome-wide association study of electrocardiographic conduction measures in an isolated founder population: Kosrae. (2009) (79)
- Decreased Cocaine Self-Administration in Kir3 Potassium Channel Subunit Knockout Mice (2003) (79)
- Molecular genetics of myeloid leukemia: identification of the commonly deleted segment of chromosome 20. (1993) (78)
- Loss of microRNA-7a2 induces hypogonadotropic hypogonadism and infertility (2017) (77)
- Systematic Proteomic Analysis Identifies β-Site Amyloid Precursor Protein Cleaving Enzyme 2 and 1 (BACE2 and BACE1) Substrates in Pancreatic β-Cells* (2013) (76)
- Molecular etiologies of mody and other early-onset forms of diabetes (2002) (76)
- MicroRNA-96 Directly Inhibits γ-Globin Expression in Human Erythropoiesis (2011) (75)
- Evaluating potential for whole-genome studies in Kosrae, an isolated population in Micronesia (2006) (74)
- Regulation of adaptive behaviour during fasting by hypothalamic Foxa2 (2009) (72)
- Human Glucagon-Like Peptide-1 Receptor Gene: Localization to Chromosome Band 6p21 by Fluorescence In Situ Hybridization and Linkage of a Highly Polymorphic Simple Tandem Repeat DNA Polymorphism to Other Markers on Chromosome 6 (1993) (71)
- GIRK2 deficient mice Evidence for hyperactivity and reduced anxiety (2001) (69)
- Foxa2 Activity Increases Plasma High Density Lipoprotein Levels by Regulating Apolipoprotein M* (2008) (67)
- Human fructose-1,6-bisphosphatase gene (FBP1): exon-intron organization, localization to chromosome bands 9q22.2-q22.3, and mutation screening in subjects with fructose-1,6-bisphosphatase deficiency. (1995) (64)
- Dissecting the transcriptional network of pancreatic islets during development and differentiation (2001) (64)
- Harnessing a Physiologic Mechanism for siRNA Delivery With Mimetic Lipoprotein Particles (2012) (62)
- MicroRNA‐194 is a target of transcription factor 1 (Tcf1, HNF1α) in adult liver and controls expression of frizzled‐6 (2012) (60)
- Functional characterization of the MODY1 gene mutations HNF4(R127W), HNF4(V255M), and HNF4(E276Q). (1999) (60)
- The multi-subunit GID/CTLH E3 ubiquitin ligase promotes cell proliferation and targets the transcription factor Hbp1 for degradation (2018) (57)
- Genetics of NIDDM in France: Studies With 19 Candidate Genes in Affected Sib Pairs (1997) (57)
- The UL16 gene of human cytomegalovirus encodes a glycoprotein that is dispensable for growth in vitro (1992) (57)
- Hyperalgesia and blunted morphine analgesia in G protein-gated potassium channel subunit knockout mice (2002) (56)
- Human somatostatin receptor genes: localization to human chromosomes 14, 17, and 22 and identification of simple tandem repeat polymorphisms. (1993) (49)
- Human KRML (MAFB): cDNA cloning, genomic structure, and evaluation as a candidate tumor suppressor gene in myeloid leukemias. (1999) (49)
- Profound defects in pancreatic beta-cell function in mice with combined heterozygous mutations in Pdx-1, Hnf-1alpha, and Hnf-3beta. (2002) (48)
- A yeast artificial chromosome-based map of the region of chromosome 20 containing the diabetes-susceptibility gene, MODY1, and a myeloid leukemia related gene. (1996) (46)
- Candidate genes involved in cardiovascular risk factors by a family-based association study on the island of Kosrae, Federated States of Micronesia. (2002) (46)
- Elevated Expression of the G-Protein-Activated Inwardly Rectifying Potassium Channel 2 (GIRK2) in Cerebellar Unipolar Brush Cells of a Down Syndrome Mouse Model (2006) (44)
- Isolation of a cDNA Clone Encoding a KATP Channel–Like Protein Expressed in Insulin-Secreting Cells, Localization of the Human Gene to Chromosome Band 21q22.1, and Linkage Studies With NIDDM (1995) (43)
- Pancreatic β Cell-specific Transcription of thepdx-1 Gene (2000) (42)
- Search for a Third Susceptibility Gene for Maturity-Onset Diabetes of the Young: Studies With Eleven Candidate Genes (1994) (42)
- Refinement of the commonly deleted segment in myeloid leukemias with a del(20q) (1998) (41)
- G-Protein-Gated Potassium (GIRK) Channels Containing the GIRK2 Subunit Are Control Hubs for Pharmacologically Induced Hypothermic Responses (2005) (41)
- Localization of human homeodomain transcription factor insulin promoter factor 1 (IPF1) to chromosome band 13q12.1. (1995) (40)
- Modulation of microRNA-375 expression alters voltage-gated Na+ channel properties and exocytosis in insulin-secreting cells (2015) (40)
- Regulation of wingless-type MMTV integration site family (WNT) signalling in pancreatic islets from wild-type and obese mice (2009) (40)
- Targeted proteomics reveals strain-specific changes in the mouse insulin and central metabolic pathways after a sustained high-fat diet (2013) (40)
- Navigating the pathway from embryonic stem cells to beta cells. (2004) (39)
- The Lin28/let-7 axis is critical for myelination in the peripheral nervous system (2015) (38)
- Fas cell surface death receptor controls hepatic lipid metabolism by regulating mitochondrial function (2017) (36)
- Bone marrow: an extra-pancreatic hideout for the elusive pancreatic stem cell? (2003) (36)
- Hyperactivity and dopamine D1 receptor activation in mice lacking girk2 channels (2002) (35)
- G Protein-Activated Inwardly Rectifying Potassium Channel (GIRK1/KGA) mRNA in Adult Rat Heart and Brain by in Situ Hybridization Histochemistry (1994) (35)
- Identification of microsatellite markers linked to the human leptin receptor gene on chromosome 1. (1996) (35)
- Increased power of mixed models facilitates association mapping of 10 loci for metabolic traits in an isolated population. (2011) (34)
- Apolipoprotein M modulates erythrocyte efflux and tubular reabsorption of sphingosine-1-phosphate (2014) (33)
- Human G-protein-coupled inwardly rectifying potassium channel (GIRK1) gene (KCNJ3): localization to chromosome 2 and identification of a simple tandem repeat polymorphism. (1994) (33)
- The RNA-binding protein vigilin regulates VLDL secretion through modulation of Apob mRNA translation (2016) (31)
- Erratum: Human glucokinase gene: Isolation, characterization, and identification of two missense mutations linked to early-onset non-insulin- dependent (type 2) diabetes mellitus (Proc. Natl. Acad. Sci. USA (August 15, 1992) 89 (7698-7702)) (1992) (31)
- Multimodal imaging of pancreatic beta cells in vivo by targeting transmembrane protein 27 (TMEM27) (2012) (31)
- Decreased glibenclamide uptake in hepatocytes of hepatocyte nuclear factor-1alpha-deficient mice: a mechanism for hypersensitivity to sulfonylurea therapy in patients with maturity-onset diabetes of the young, type 3 (MODY3). (2002) (30)
- In vivo cytidine base editing of hepatocytes without detectable off-target mutations in RNA and DNA (2021) (30)
- Nuclear Export-independent Inhibition of Foxa2 by Insulin* (2009) (29)
- The pancreatic beta cell surface proteome (2012) (29)
- The Human HNF-3 Genes: Cloning, Partial Sequence and Mutation Screening in Patients with Impaired Glucose Homeostasis (2000) (28)
- Pancreatic Islet Expression Studies and Polymorphic DNA Markers in the Genes Encoding Hepatocyte Nuclear Factor-3α, -3β, -3γ, -4γ, and -6 (1997) (27)
- No Evidence for Mutations in a Putative β-Cell ATP-Sensitive K+ Channel Subunit in MODY, NIDDM, or GDM (1995) (27)
- cDNA sequence and localization of polymorphic human cytosolic phosphoenolpyruvate carboxykinase gene (PCK1) to chromosome 20, band q13.31: PCK1 is not tightly linked to maturity-onset diabetes of the young. (1993) (26)
- Systematic haplotype analysis resolves a complex plasma plant sterol locus on the Micronesian Island of Kosrae (2009) (25)
- Low-Pass Genome-Wide Sequencing and Variant Inference Using Identity-by-Descent in an Isolated Human Population (2012) (25)
- Cloning of rat KATP-2 channel and decreased expression in pancreatic islets of male Zucker diabetic fatty rats. (1995) (24)
- Phytosterolemia on the island of Kosrae: founder effect for a novel ABCG8 mutation results in high carrier rate and increased plasma plant sterol levels. (2004) (24)
- Assignment of the gene encoding glycogen synthase (GYS) to human chromosome 19, band q13.3. (1993) (23)
- Mutations of the human glucokinase gene and diabetes mellitus (1993) (23)
- The human mitochondrial citrate transporter gene (SLC20A3) maps to chromosome band 22q11 within a region implicated in DiGeorge syndrome, velo-cardio-facial syndrome and schizophrenia (1996) (23)
- Human pancreatic Beta-cell glucokinase: cDNA sequence and localization of the polymorphic gene to chromosome 7, band p 13 (1992) (23)
- Localization of the glucagon receptor gene to human chromosome band 17q25. (1994) (22)
- Epilepsy genes: excitement traced to potassium channels (1998) (22)
- The RNA-Binding Protein A1CF Regulates Hepatic Fructose and Glycerol Metabolism via Alternative RNA Splicing. (2019) (21)
- Human hexokinase II: localization of the polymorphic gene to chromosome 2 (1993) (20)
- The Diabetes Gene JAZF1 Is Essential for the Homeostatic Control of Ribosome Biogenesis and Function in Metabolic Stress. (2020) (20)
- Pancreatic islet expression studies and polymorphic DNA markers in the genes encoding hepatocyte nuclear factor-3alpha, -3beta, -3gamma, -4gamma, and -6. (1997) (18)
- Impaired glucose homeostasis and neonatal mortality in hepatocyte nuclear factor 3 a-deficient mice ( hypoglycemia y proglucagon y neuropeptide Y y pancreatic islet cells ) (1999) (17)
- Non-linkage of the glucagon-like peptide 1 receptor gene with maturity onset diabetes of the young (1994) (16)
- Pancreatic b Cell-specific Transcription of the pdx-1 Gene THE ROLE OF CONSERVED UPSTREAM CONTROL REGIONS AND THEIR HEPATIC NUCLEAR FACTOR 3 SITES* (2000) (16)
- Tmem27 dimerization, deglycosylation, plasma membrane depletion, and the extracellular Phe-Phe motif are negative regulators of cleavage by Bace2 (2012) (15)
- European admixture on the Micronesian island of Kosrae: lessons from complete genetic information (2009) (14)
- Foxa1 is essential for development and functional integrity of the subthalamic nucleus (2016) (14)
- miR-802 Suppress Acinar-to-Ductal Reprogramming during Early Pancreatitis and Pancreatic Carcinogenesis. (2021) (13)
- miR-802 regulates Paneth cell function and enterocyte differentiation in the mouse small intestine (2021) (13)
- Microsatellite polymorphism in the human platelet glycoprotein IIIa gene (GP3A) on chromosome 17. (1992) (12)
- CDK8 Regulates Insulin Secretion and Mediates Postnatal and Stress-Induced Expression of Neuropeptides in Pancreatic β Cells. (2019) (12)
- Structural organization and mapping of the human mitochondrial glycerol phosphate dehydrogenase-encoding gene and pseudogene. (1996) (12)
- MicroRNA-7 a regulates pancreatic beta cell function (2017) (12)
- Therapeutic RNA-silencing oligonucleotides in metabolic diseases (2022) (10)
- Kin of IRRE-like Protein 2 Is a Phosphorylated Glycoprotein That Regulates Basal Insulin Secretion* (2015) (10)
- Human type I pituitary adenylate cyclase activating polypeptide receptor (ADCYAP1R): localization to chromosome band 7p14 and integration into the cytogenetic, physical, and genetic map of chromosome 7. (1994) (9)
- High‐Throughput Single‐Cell Mass Spectrometry Reveals Abnormal Lipid Metabolism in Pancreatic Ductal Adenocarcinoma (2021) (9)
- Automated Assessment of β-Cell Area and Density per Islet and Patient Using TMEM27 and BACE2 Immunofluorescence Staining in Human Pancreatic β-Cells (2014) (9)
- Defective g-aminobutyric acid type B receptor-activated inwardly rectifying K 1 currents in cerebellar granule cells isolated from weaver and Girk 2 null mutant mice (1997) (9)
- Single-Stranded Conformational Polymorphism Analysis of the Mitochondria! Glycerol Phosphate Dehydrogenase Gene in NIDDM (1997) (7)
- Apolipoprotein M and Sphingosine-1-Phosphate Receptor 1 Promote the Transendothelial Transport of High-Density Lipoprotein (2021) (7)
- SIK2 regulates insulin secretion (2014) (6)
- Candidate gene studies in pedigrees with maturity-onset diabetes of the young not linked with glucokinase (1995) (6)
- Dysregulation of the Pdx1/Ovol2/Zeb2 axis in dedifferentiated β-cells triggers the induction of genes associated with epithelial–mesenchymal transition in diabetes (2021) (6)
- MicroRNA-7a2 regulates prolactin in developing lactotrophs and prolactinoma cells. (2020) (6)
- The Long, the Short, and the Unstructured: A Unifying Model of miRNA Biogenesis. (2015) (6)
- Reply to Diet-responsive MicroRNAs Are Likely Exogenous (2015) (6)
- Regulation of transcriptional coactivator PGC-1alpha. (2004) (6)
- Mitochondrial FAD-Glycerophosphate Dehydrogenase and G-Protein—Coupled Inwardly Rectifying K+ Channel: No Evidence for Linkage in Maturity-Onset Diabetes of the Young or NIDDM (1996) (5)
- Longitudinal study shows increasing obesity and hyperglycemia in micronesia (2013) (5)
- Assignment of the gastric inhibitory polypeptide receptor gene (GIPR) to chromosome bands 19q13.2-q13.3 by fluorescence in situ hybridization. (1995) (5)
- Human insulin receptor substrate-1 gene (IRS1): chromosomal localization to 2q35-q36.1 and identification of a simple tandem repeat DNA polymorphism (1993) (4)
- The miR-200–Zeb1 axis regulates key aspects of β-cell function and survival in vivo (2021) (3)
- Selective ablation of P53 in pancreatic beta cells fails to ameliorate glucose metabolism in genetic, dietary and pharmacological models of diabetes mellitus (2022) (3)
- Grainyhead 1 acts as a drug-inducible conserved transcriptional regulator linked to insulin signaling and lifespan (2022) (3)
- The Role of the Hepatocyte Nuclear Factor Network in Glucose Homeostasis (2001) (3)
- MicroRNA-7 regulates melanocortin circuits involved in mammalian energy homeostasis (2022) (3)
- Dinucleotide repeat polymorphism at the human ribophorin II locus (RPN2) on chromosome 20q. (1992) (3)
- Low-pass Genomewide Sequencing and Variant Imputation Using Identity-by-descent in an Isolated Human Population (2011) (2)
- miR-375 gene dosage in pancreatic β-cells: implications for regulation of β-cell mass and biomarker development (2015) (2)
- Impact of MicroRNA Level s , Target-Site Complementarity , and Cooperativity on Competing Endogenous RNA-Regulated Gene Expression Graphical (2016) (2)
- Maturity-Onset Diabetes of the Young: Molecular Genetics, Clinical Manifestations and Therapy (2010) (2)
- β-cell dedifferentiation is associated with epithelial-mesenchymal transition triggered by miR-7-mediated repression of mSwi/Snf complex (2019) (1)
- Automated Assessment of b-Cell Area and Density per Islet and Patient Using TMEM 27 and BACE 2 Immunofluorescence Staining in Human Pancreatic b-Cells (2018) (1)
- Characterization of a third simple tandem repeat polymorphism in the human glucokinase gene (1993) (1)
- SF3B1 promotes tumor malignancy through splicing-independent co-activation of HIF1α (2020) (1)
- Fas cell surface death receptor controls hepatic lipid metabolism by regulating mitochondrial function (2017) (1)
- Genetic dissection of the miR-200–Zeb1 axis reveals its importance in tumor differentiation and invasion (2018) (1)
- Systematic Proteomic Analysis Identifies (cid:1) -Site Amyloid Precursor Protein Cleaving Enzyme 2 and 1 (BACE2 and BACE1) Substrates in Pancreatic (cid:1) -Cells (2020) (1)
- Phytosterolemia on the island of Kosrae Published, JLR Papers in Press, June 21, 2004. DOI 10.1194/jlr.M400006-JLR200 (2004) (0)
- Mutant SF3B1 promotes PDAC malignancy through TGF-β resistance (2022) (0)
- RO6807936 as a Novel PET Radiotracer for in Vitro and in Vivo Visualization and Quantification of BACE1 in the Rodent and Baboon Brain. (2023) (0)
- Genome-Wide Association Studies in an Isolated Founder Population from the Pacific Island of Kosrae Citation Lowe (2009) (0)
- Mass Spectrometry Reveals High Levels of Hydrogen Peroxide in Pancreatic Cancer Cells. (2023) (0)
- MicroRNA-96 Inhibits Fetal Hemoglobin Expression During Erythropoiesis (2010) (0)
- Apolipoprotein m modulates erythrocyte efflux and urinary excretion of sphingosine-1-phosphate (2014) (0)
- Distribution of BACE1 in the rodent, monkey and human brain (2012) (0)
- Islet mitogens ndash role in the maintenance of beta-cell mass (2005) (0)
- Grainyhead 1 acts as a drug-inducible conserved transcriptional regulator linked to insulin signaling and lifespan (2022) (0)
- Reduced (cid:1) -cell mass and altered glucose sensing impair insulin-secretory function in (cid:1) IRKO mice (2003) (0)
- In vivo cytidine base editing of hepatocytes without detectable off-target mutations in RNA and DNA (2021) (0)
- SF3B1 facilitates HIF1-signaling and promotes malignancy in pancreatic cancer. (2022) (0)
- Azzouzi et al. 2011 PLoS ONE (2012) (0)
- Role of the Hepatocyte Nuclear Factor Network in Maturity-Onset Diabetes of the Young (MODY) (2000) (0)
- MicroRNAs: Biological Functions and Therapeutic Opportunities.Markus Stoffel, M.D., Ph.D. (2009) (0)
- ciRS-7-miR7 regulate ischemia induced neuronal death via glutamatergic signaling (2023) (0)
- NO EVIDENCE FOR MUTATIONS IN THE BETA-CELL ATP-SENSITIVE POTASSIUM CHANNEL IN MODY, NIDDM OR GESTATIONAL DIABETES (1995) (0)
- 1 NUCLEAR EXPORT-INDEPENDENT INHIBITION OF FOXA 2 BY INSULIN (2009) (0)
- Dissecting the transcriptiona islets during development an (2016) (0)
- Insulin Resistance: Hepatic Molecular Switches Gone Wrong?: Foxa2 Regulates Lipid Metabolism and Ketogenesis in the Liver during Fasting and in Diabetes. Nature 432: 1027-1032, 2004. (2005) (0)
- Type 2 Diabetes risk alleles in Peptidyl-glycine Alpha-amidating Monooxygenase influence GLP-1 levels and response to GLP-1 Receptor Agonists (2023) (0)
- Microarray-based gene expression profiles applied to pharmaco-and toxicogenomics Determining patterns of altered gene expression will provide a rational basis for making drug development decisions in a cost-and time-efficient manner (2003) (0)
- Author response: The multi-subunit GID/CTLH E3 ubiquitin ligase promotes cell proliferation and targets the transcription factor Hbp1 for degradation (2018) (0)
- The MAPK p38δ Regulate Glucose Homeostasis by Suppressing Insulin Secretion from Pancreatic β Cells (2019) (0)
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