Martin Biel

Q: What Schools Are Affiliated With Martin Biel

Martin Biel is affiliated with the following schools: University of California, Berkeley, Ludwig Maximilian University of Munich, Stanford University, Technical University of Munich

Martin Biel's AcademicInfluence.com Rankings

Martin Biel

Computer Science

#8404

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#8836

Historical Rank

Computational Linguistics

#1863

World Rank

#1883

Historical Rank

Machine Learning

#3434

World Rank

#3477

Historical Rank

Artificial Intelligence

#3733

World Rank

#3788

Historical Rank

computer-science Degrees

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Computer Science

Martin Biel's Degrees

PhD Computer Science Stanford University
Masters Computer Science University of California, Berkeley
Bachelors Computer Science University of California, Berkeley

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Martin Biel's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Melanopsin and rod–cone photoreceptive systems account for all major accessory visual functions in mice (2003) (1121)
A family of hyperpolarization-activated mammalian cation channels (1998) (947)
Hyperpolarization-activated cation channels: from genes to function. (2009) (860)
Tissue Distribution of 5-Hydroxymethylcytosine and Search for Active Demethylation Intermediates (2010) (796)
Genetic Reactivation of Cone Photoreceptors Restores Visual Responses in Retinitis Pigmentosa (2010) (586)
The roles of the subunits in the function of the calcium channel. (1991) (557)
Lack of an endothelial store-operated Ca2+ current impairs agonist-dependent vasorelaxation in TRP4−/− mice (2001) (549)
Absence epilepsy and sinus dysrhythmia in mice lacking the pacemaker channel HCN2 (2003) (506)
Molecular basis for Ca2+ channel diversity. (1994) (461)
The hyperpolarization-activated channel HCN4 is required for the generation of pacemaker action potentials in the embryonic heart (2003) (444)
Cellular expression and functional characterization of four hyperpolarization-activated pacemaker channels in cardiac and neuronal tissues. (2001) (421)
Two-pore channels control Ebola virus host cell entry and are drug targets for disease treatment (2015) (402)
HCN channels: Structure, cellular regulation and physiological function (2009) (389)
Two pacemaker channels from human heart with profoundly different activation kinetics (1999) (386)
Primary structure of the beta subunit of the DHP-sensitive calcium channel from skeletal muscle. (1989) (366)
Quantification of the sixth DNA base hydroxymethylcytosine in the brain. (2010) (364)
Calcium channel beta subunit heterogeneity: functional expression of cloned cDNA from heart, aorta and brain. (1992) (351)
Selective loss of cone function in mice lacking the cyclic nucleotide-gated channel CNG3. (1999) (292)
Cardiac HCN channels: structure, function, and modulation. (2002) (266)
The two-pore channel TPCN2 mediates NAADP-dependent Ca2+-release from lysosomal stores (2009) (263)
Differential Distribution of Four Hyperpolarization-Activated Cation Channels in Mouse Brain (1999) (250)
New views on RPE65 deficiency: the rod system is the source of vision in a mouse model of Leber congenital amaurosis (2001) (242)
Primary structure and functional expression of a high voltage activated calcium channel from rabbit lung (1990) (230)
Contribution of the receptor guanylyl cyclase GC-D to chemosensory function in the olfactory epithelium (2007) (208)
Role of Subunit Heteromerization and N-Linked Glycosylation in the Formation of Functional Hyperpolarization-activated Cyclic Nucleotide-gated Channels* (2003) (192)
Another member of the cyclic nucleotide-gated channel family, expressed in testis, kidney, and heart. (1994) (187)
Exploring HCN channels as novel drug targets (2011) (182)
Restoration of cone vision in the CNGA3-/- mouse model of congenital complete lack of cone photoreceptor function. (2010) (179)
High susceptibility to fatty liver disease in two-pore channel 2-deficient mice (2014) (164)
Primary structure and functional expression of a cyclic nucleotidegated channel from rabbit aorta (1993) (161)
Identification of a Common Non-Apoptotic Cell Death Mechanism in Hereditary Retinal Degeneration (2014) (157)
Impaired Channel Targeting and Retinal Degeneration in Mice Lacking the Cyclic Nucleotide-Gated Channel Subunit CNGB1 (2005) (151)
An Olfactory Subsystem that Detects Carbon Disulfide and Mediates Food-Related Social Learning (2010) (149)
Characterization of Two-pore Channel 2 (TPCN2)-mediated Ca2+ Currents in Isolated Lysosomes* (2010) (139)
Expression of Ca2+-permeable two-pore channels rescues NAADP signalling in TPC-deficient cells (2015) (132)
Differential and age-dependent expression of hyperpolarization-activated, cyclic nucleotide-gated cation channel isoforms 1–4 suggests evolving roles in the developing rat hippocampus (2001) (131)
Molecular Cloning and Functional Characterization of a New Modulatory Cyclic Nucleotide-Gated Channel Subunit from Mouse Retina (2000) (130)
Functional characterization of the L-type Ca2+ channel Cav1.4alpha1 from mouse retina. (2004) (128)
THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Ion channels (2021) (122)
Impaired opsin targeting and cone photoreceptor migration in the retina of mice lacking the cyclic nucleotide-gated channel CNGA3. (2005) (122)
An isoform of the rod photoreceptor cyclic nucleotide-gated channel beta subunit expressed in olfactory neurons. (1998) (118)
A Novel Mechanism of Modulation of Hyperpolarization-activated Cyclic Nucleotide-gated Channels by Src Kinase*[boxs] (2005) (115)
Cyclic nucleotide-gated channels. (2009) (115)
Absence of the γ Subunit of the Skeletal Muscle Dihydropyridine Receptor Increases L-type Ca2+ Currents and Alters Channel Inactivation Properties* (2000) (113)
A small molecule restores function to TRPML1 mutant isoforms responsible for mucolipidosis type IV (2014) (112)
TET3 is recruited by REST for context-specific hydroxymethylation and induction of gene expression. (2015) (108)
Hyperpolarization-activated cation channels: a multi-gene family. (1999) (107)
Dominant-Negative Suppression of HCN Channels Markedly Reduces the Native Pacemaker Current If and Undermines Spontaneous Beating of Neonatal Cardiomyocytes (2003) (105)
Two-Pore Channel Function Is Crucial for the Migration of Invasive Cancer Cells. (2017) (104)
The Murine HCN3 Gene Encodes a Hyperpolarization-activated Cation Channel with Slow Kinetics and Unique Response to Cyclic Nucleotides* (2005) (104)
Synaptic Plasticity in CNGA3−/− Mice: Cone Bipolar Cells React on the Missing Cone Input and Form Ectopic Synapses with Rods (2006) (101)
Switching off calcium-dependent inactivation in l-type calcium channels by an autoinhibitory domain (2006) (99)
A key role for cyclic nucleotide gated (CNG) channels in cGMP-related retinitis pigmentosa. (2011) (97)
Cyclic Nucleotide-regulated Cation Channels* (2009) (94)
AAV8 Can Induce Innate and Adaptive Immune Response in the Primate Eye. (2017) (91)
International Union of Pharmacology. LI. Nomenclature and Structure-Function Relationships of Cyclic Nucleotide-Regulated Channels (2005) (91)
Tissue-specific expression of high-voltage-activated dihydropyridine-sensitive L-type calcium channels. (1991) (90)
Structure and Function of Cardiac Pacemaker Channels (1999) (90)
Vision tests in the mouse: Functional phenotyping with electroretinography. (2009) (88)
Gene therapy restores vision and delays degeneration in the CNGB1(-/-) mouse model of retinitis pigmentosa. (2012) (85)
Morphological characterization of the retina of the CNGA3(-/-)Rho(-/-) mutant mouse lacking functional cones and rods. (2004) (85)
The cDNA and deduced amino acid sequence of the γ subunit of the L‐type calcium channel from rabbit skeletal muscle (1990) (83)
Agonist-mediated switching of ion selectivity in TPC2 differentially promotes lysosomal function (2020) (83)
Grating acuity at different luminances in wild-type mice and in mice lacking rod or cone function. (2005) (81)
Three amino acids in the C‐linker are major determinants of gating in cyclic nucleotide‐gated channels (1998) (81)
KCNMA1 Encoded Cardiac BK Channels Afford Protection against Ischemia-Reperfusion Injury (2014) (79)
Loss of CNGB1 Protein Leads to Olfactory Dysfunction and Subciliary Cyclic Nucleotide-gated Channel Trapping* (2006) (79)
Sick Sinus Syndrome in HCN1-Deficient Mice (2013) (76)
Function and Dysfunction of CNG Channels: Insights from Channelopathies and Mouse Models (2007) (75)
Modulation of cardiac Ca2+ channels in Xenopus oocytes by protein kinase C (1992) (75)
Structure and function of cyclic nucleotide-gated channels. (1999) (73)
Role of TRPML and Two-Pore Channels in Endolysosomal Cation Homeostasis (2012) (71)
A Single Histidine Residue Determines the pH Sensitivity of the Pacemaker Channel HCN2* (2001) (71)
Safety and Vision Outcomes of Subretinal Gene Therapy Targeting Cone Photoreceptors in Achromatopsia (2020) (71)
HCN3 Contributes to the Ventricular Action Potential Waveform in the Murine Heart (2011) (67)
Gene therapy restores vision and delays degeneration in the CNGB1(-/-) mouse model of retinitis pigmentosa. (2014) (67)
Expression of cyclic nucleotide-gated cation channels in non-sensory tissues and cells (1994) (65)
Rods in daylight act as relay cells for cone-driven horizontal cell–mediated surround inhibition (2014) (63)
Molecular Cloning and Expression of a Modulatory Subunit of the Cyclic Nucleotide-gated Cation Channel (*) (1996) (63)
Molecular Basis for the Different Activation Kinetics of the Pacemaker Channels HCN2 and HCN4* (2003) (62)
Regulation of Hyperpolarization-activated Cyclic Nucleotide-gated (HCN) Channel Activity by cCMP* (2012) (61)
Superior Retinal Gene Transfer and Biodistribution Profile of Subretinal Versus Intravitreal Delivery of AAV8 in Nonhuman Primates. (2017) (61)
Two-Pore Channels: Catalyzers of Endolysosomal Transport and Function (2017) (60)
Investigation of the Immunogenicity of Different Types of Aggregates of a Murine Monoclonal Antibody in Mice (2015) (60)
Grueneberg Ganglion Neurons Are Finely Tuned Cold Sensors (2010) (59)
cGMP Accumulation Causes Photoreceptor Degeneration in CNG Channel Deficiency: Evidence of cGMP Cytotoxicity Independently of Enhanced CNG Channel Function (2013) (59)
Retinal gene delivery by adeno-associated virus (AAV) vectors: Strategies and applications. (2015) (58)
Mutations in the S4 domain of a pacemaker channel alter its voltage dependence (2000) (58)
Planar Patch Clamp Approach to Characterize Ionic Currents from Intact Lysosomes (2010) (57)
Humoral Immune Response After Intravitreal But Not After Subretinal AAV8 in Primates and Patients. (2018) (54)
Biocompatibility of a genetically encoded calcium indicator in a transgenic mouse model (2012) (52)
Cone Genesis Tracing by the Chrnb4-EGFP Mouse Line: Evidences of Cellular Material Fusion after Cone Precursor Transplantation (2017) (52)
Patch-clamp technique to characterize ion channels in enlarged individual endolysosomes (2017) (52)
NAADP and the two-pore channel protein 1 participate in the acrosome reaction in mammalian spermatozoa (2014) (52)
Rod and Cone Contributions to Horizontal Cell Light Responses in the Mouse Retina (2008) (50)
Selective agonist of TRPML2 reveals direct role in chemokine release from innate immune cells (2018) (49)
cAMP-dependent regulation of HCN4 controls the tonic entrainment process in sinoatrial node pacemaker cells (2020) (49)
From mucolipidosis type IV to Ebola: TRPML and two-pore channels at the crossroads of endo-lysosomal trafficking and disease. (2017) (49)
Endolysosomal Cation Channels and Cancer—A Link with Great Potential (2018) (48)
Complex Regulation of Voltage-dependent Activation and Inactivation Properties of Retinal Voltage-gated Cav1.4 L-type Ca2+ Channels by Ca2+-binding Protein 4 (CaBP4)* (2012) (47)
Cellular Zinc Levels Are Modulated by TRPML1–TMEM163 Interaction (2014) (47)
Retinal Cyclic Nucleotide-Gated Channels: From Pathophysiology to Therapy (2018) (47)
HCN channels: new roles in sinoatrial node function. (2014) (47)
Direct Inhibition of Cardiac Hyperpolarization-Activated Cyclic Nucleotide–Gated Pacemaker Channels by Clonidine (2007) (46)
Electroretinographic assessment of rod- and cone-mediated bipolar cell pathways using flicker stimuli in mice (2015) (46)
Phosducin influences sympathetic activity and prevents stress-induced hypertension in humans and mice. (2009) (45)
Endoplasmic Reticulum Stress-associated Cone Photoreceptor Degeneration in Cyclic Nucleotide-gated Channel Deficiency* (2012) (45)
HCN2 channels in local inhibitory interneurons constrain LTP in the hippocampal direct perforant path (2010) (45)
Tissue-specific expression of calcium channels. (1993) (43)
Comprehensive multilevel in vivo and in vitro analysis of heart rate fluctuations in mice by ECG telemetry and electrophysiology (2015) (43)
CNGA3: A Target of Spinal Nitric Oxide/cGMP Signaling and Modulator of Inflammatory Pain Hypersensitivity (2011) (43)
Quantifying macromolecular interactions in living cells using FRET two-hybrid assays (2016) (42)
TPC2 polymorphisms associated with a hair pigmentation phenotype in humans result in gain of channel function by independent mechanisms (2017) (41)
DNA methylation and differential gene regulation in photoreceptor cell death (2014) (40)
Cardiac calcium channels expressed in Xenopus oocytes are modulated by dephosphorylation but not by cAMP-dependent phosphorylation. (1994) (40)
Cyclic nucleotide-gated channels – mediators of NO:cGMP-regulated processes (1998) (40)
Retinitis pigmentosa: impact of different Pde6a point mutations on the disease phenotype. (2015) (39)
Photopharmacological control of bipolar cells restores visual function in blind mice (2017) (39)
Chemo- and Thermosensory Responsiveness of Grueneberg Ganglion Neurons Relies on Cyclic Guanosine Monophosphate Signaling Elements (2011) (38)
Restoring Light Sensitivity in Blind Retinae Using a Photochromic AMPA Receptor Agonist (2015) (38)
The cyclic nucleotide-gated ion channel CNGA3 contributes to coolness-induced responses of Grueneberg ganglion neurons (2010) (38)
Optimized technique for subretinal injections in mice. (2013) (37)
Characterization of neurite outgrowth and ectopic synaptogenesis in response to photoreceptor dysfunction (2013) (37)
Novel AAV capsids for intravitreal gene therapy of photoreceptor disorders (2021) (37)
Isotope-Based Analysis of Modified tRNA Nucleosides Correlates Modification Density with Translational Efficiency** (2012) (36)
cGMP/Protein Kinase G Signaling Suppresses Inositol 1,4,5-Trisphosphate Receptor Phosphorylation and Promotes Endoplasmic Reticulum Stress in Photoreceptors of Cyclic Nucleotide-gated Channel-deficient Mice* (2015) (35)
Gene therapy for achromatopsia (2017) (34)
Determination of Rod and Cone Influence to the Early and Late Dynamic of the Pupillary Light Response (2016) (34)
The two-pore channel TPC1 is required for efficient protein processing through early and recycling endosomes (2017) (33)
Quantitative Bestimmung der sechsten DNA-Base Hydroxymethylcytosin im Gehirn† (2010) (33)
Calmodulin Is a Functional Regulator of Cav1.4 L-type Ca2+ Channels* (2009) (33)
Residual photosensitivity in mice lacking both rod opsin and cone photoreceptor cyclic nucleotide gated channel 3 α subunit (2004) (32)
International Union of Pharmacology. XLII. Compendium of Voltage-Gated Ion Channels: Cyclic Nucleotide-Modulated Channels (2003) (30)
An Arginine Residue in the Pore Region Is a Key Determinant of Chloride Dependence in Cardiac Pacemaker Channels* (2005) (30)
Subretinal Injection for Gene Therapy Does Not Cause Clinically Significant Outer Nuclear Layer Thinning in Normal Primate Foveae. (2017) (30)
Gene replacement therapy for retinal CNG channelopathies (2013) (29)
The Glutamic Acid-Rich Protein Is a Gating Inhibitor of Cyclic Nucleotide-Gated Channels (2011) (29)
Small Molecules for Early Endosome-Specific Patch Clamping. (2017) (28)
Early Microglia Activation Precedes Photoreceptor Degeneration in a Mouse Model of CNGB1-Linked Retinitis Pigmentosa (2018) (28)
Induction of STAT3-related genes in fast degenerating cone photoreceptors of cpfl1 mice (2010) (25)
Odorant-evoked electrical responses in Grueneberg ganglion neurons rely on cGMP-associated signaling proteins (2013) (25)
The enhancement of HCN channel instantaneous current facilitated by slow deactivation is regulated by intracellular chloride concentration (2006) (25)
Gene therapy restores missing cone-mediated vision in the CNGA3-/- mouse model of achromatopsia. (2012) (24)
Hif1a inactivation rescues photoreceptor degeneration induced by a chronic hypoxia-like stress (2018) (24)
In vivo analysis of cone survival in mice. (2010) (24)
AAV Vectors for FRET-Based Analysis of Protein-Protein Interactions in Photoreceptor Outer Segments (2016) (24)
Mosaic synaptopathy and functional defects in Cav1.4 heterozygous mice and human carriers of CSNB2. (2017) (24)
Molecular cloning of cyclic nucleotide-gated cation channel subunits from rat pineal gland. (1997) (24)
AAV-Mediated Gene Supplementation Therapy in Achromatopsia Type 2: Preclinical Data on Therapeutic Time Window and Long-Term Effects (2017) (24)
Flavonoids increase melanin production and reduce proliferation, migration and invasion of melanoma cells by blocking endolysosomal/melanosomal TPC2 (2021) (23)
CNGA3 deficiency affects cone synaptic terminal structure and function and leads to secondary rod dysfunction and degeneration. (2012) (23)
Vitreal delivery of AAV vectored Cnga3 restores cone function in CNGA3-/-/Nrl-/- mice, an all-cone model of CNGA3 achromatopsia. (2015) (23)
Pathological α-synuclein impairs adult-born granule cell development and functional integration in the olfactory bulb (2014) (23)
Development of Methodology and Study Protocol: Safety and Efficacy of a Single Subretinal Injection of rAAV.hCNGA3 in Patients with CNGA3-Linked Achromatopsia Investigated in an Exploratory Dose-Escalation Trial. (2018) (22)
Up-regulation of Hyperpolarization-activated Cyclic Nucleotide-gated Channel 3 (HCN3) by Specific Interaction with K+ Channel Tetramerization Domain-containing Protein 3 (KCTD3)* (2013) (22)
Cyclic nucleotide-gated cation channels molecular diversity, structure, and cellular functions. (1996) (22)
Loss of cone cyclic nucleotide-gated channel leads to alterations in light response modulating system and cellular stress response pathways: a gene expression profiling study. (2013) (22)
The protein interaction networks of mucolipins and two-pore channels (2018) (22)
Gene editing and synthetically accessible inhibitors reveal role for TPC2 in HCC cell proliferation and tumor growth. (2021) (22)
Peripherin-2 couples rhodopsin to the CNG channel in outer segments of rod photoreceptors. (2014) (22)
Mosaic synaptopathy and functional defects in Cav1.4 heterozygous mice and human carriers of CSNB2. (2014) (21)
Loss of HCN1 enhances disease progression in mouse models of CNG channel-linked retinitis pigmentosa and achromatopsia. (2016) (21)
Mouse Models of NO/Natriuretic Peptide/cGMP Kinase Signaling (2004) (20)
In Vivo Analysis of Disease-Associated Point Mutations Unveils Profound Differences in mRNA Splicing of Peripherin-2 in Rod and Cone Photoreceptors (2016) (20)
Accessory heterozygous mutations in cone photoreceptor CNGA3 exacerbate CNG channel–associated retinopathy (2018) (19)
A30P α-Synuclein interferes with the stable integration of adult-born neurons into the olfactory network (2014) (19)
HCN3 ion channels: roles in sensory neuronal excitability and pain (2019) (18)
Endoplasmic reticulum (ER) Ca2+-channel activity contributes to ER stress and cone death in cyclic nucleotide-gated channel deficiency (2017) (18)
Three-year results of phase I retinal gene therapy trial for CNGA3-mutated achromatopsia: results of a non randomised controlled trial (2021) (17)
Abolishing cAMP sensitivity in HCN2 pacemaker channels induces generalized seizures. (2019) (17)
Recombinant tandem of pore-domains in a Weakly Inward rectifying K+ channel 2 (TWIK2) forms active lysosomal channels (2017) (17)
TPC1 deficiency or blockade augments systemic anaphylaxis and mast cell activity (2020) (17)
TRPML2 is an osmo/mechanosensitive cation channel in endolysosomal organelles (2020) (17)
A gene therapy for inherited blindness using dCas9-VPR–mediated transcriptional activation (2020) (17)
Altered synaptic plasticity and behavioral abnormalities in CNGA3‐deficient mice (2011) (16)
Impact of Hyperpolarization-activated, Cyclic Nucleotide-gated Cation Channel Type 2 for the Xenon-mediated Anesthetic Effect: Evidence from In Vitro and In Vivo Experiments (2015) (16)
The role of HCN channels in ventricular repolarization. (2011) (16)
Corticotropin-Releasing Hormone Receptor Type 1 (CRHR1) Clustering with MAGUKs Is Mediated via Its C-Terminal PDZ Binding Motif (2015) (14)
Gene Supplementation Rescues Rod Function and Preserves Photoreceptor and Retinal Morphology in Dogs, Leading the Way Towards Treating Human PDE6A-Retinitis Pigmentosa. (2017) (13)
The Retinitis Pigmentosa Mutation c.3444+1G>A in CNGB1 Results in Skipping of Exon 32 (2010) (13)
Disturbed Processing of Contextual Information in HCN3 Channel Deficient Mice (2018) (13)
Protein kinase A regulates inflammatory pain sensitization by modulating HCN2 channel activity in nociceptive sensory neurons (2017) (12)
Lung emphysema and impaired macrophage elastase clearance in mucolipin 3 deficient mice (2022) (12)
Antisense Oligonucleotide- and CRISPR-Cas9-Mediated Rescue of mRNA Splicing for a Deep Intronic CLRN1 Mutation (2020) (12)
MicroRNA-365 regulates human cardiac action potential duration (2022) (12)
The cGMP-Dependent Protein Kinase II Is an Inhibitory Modulator of the Hyperpolarization-Activated HCN2 Channel (2011) (11)
Molecular diversity of cyclic nucleotide-gated cation channels (1995) (10)
Gene therapy successfully delays degeneration in a mouse model of PDE6A-linked retinitis pigmentosa (RP 43). (2017) (10)
HCN1 Channels Enhance Rod System Responsivity in the Retina under Conditions of Light Exposure (2016) (10)
Peripherin-2 differentially interacts with cone opsins in outer segments of cone photoreceptors. (2016) (10)
Peripherin-2 and Rom-1 have opposing effects on rod outer segment targeting of retinitis pigmentosa-linked peripherin-2 mutants (2017) (10)
Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications (2017) (10)
Comparison of Different Liquid Chromatography-Based Purification Strategies for Adeno-Associated Virus Vectors (2021) (10)
Functional expression of cardiac and smooth muscle calcium channels (1994) (10)
Structural and functional phenotyping in the cone-specific photoreceptor function loss 1 (cpfl1) mouse mutant - a model of cone dystrophies. (2010) (9)
A gene therapy for inherited blindness using dCas9-VPR-mediated transcriptional activation. (2020) (9)
Beyond pacemaking: HCN channels in sinoatrial node function. (2021) (9)
Speeding Up the Heart? Traditional and New Perspectives on HCN4 Function (2021) (8)
TPC2 promotes choroidal angiogenesis and inflammation in a mouse model of neovascular age-related macular degeneration (2021) (7)
In vivo potency testing of subretinal rAAV5.hCNGB1 gene therapy in the Cngb1 knockout mouse model of retinitis pigmentosa. (2021) (7)
High voltage activated calcium channels: molecular composition and function. (1991) (7)
Detection of cGMP in the degenerating retina. (2013) (6)
Remote and reversible inhibition of neurons and circuits by small molecule induced potassium channel stabilization (2016) (6)
The cGMP-Dependent Protein Kinase 2 Contributes to Cone Photoreceptor Degeneration in the Cnga3-Deficient Mouse Model of Achromatopsia (2020) (6)
TPC2 rescues lysosomal storage in mucolipidosis type IV, Niemann–Pick type C1, and Batten disease (2022) (6)
rAAV8 biodistribution and shedding after subretinal injection in non-human primates (2016) (6)
Intrinsic Differential Scanning Fluorimetry for Fast and Easy Identification of AAV Serotypes. (2019) (6)
Successful delivery of rAAV8.CNGA3 in a patient with CNGA3 achromatopsia (2016) (6)
Optimized Subretinal Injection Technique for Gene Therapy Approaches. (2019) (5)
Optogenetic Control of Neural Circuits in the Mongolian Gerbil (2018) (5)
Enigmatic rhodopsin mutation creates an exceptionally strong splice acceptor site. (2019) (5)
Auditory event-related signals in mouse ERG recordings (2014) (4)
Lysosomal TRPML1 regulates mitochondrial function in hepatocellular carcinoma cells (2022) (4)
In vivo and ex vivo electrophysiological study of the mouse heart to characterize the cardiac conduction system, including atrial and ventricular vulnerability (2022) (4)
Chapter 7 – HCN Channels: From Genes to Function (2004) (4)
Paradigm shift: new concepts for HCN4 function in cardiac pacemaking (2022) (4)
Redirected nuclear glutamate dehydrogenase supplies Tet3 with α-ketoglutarate in neurons (2021) (4)
Design and Development of AAV-based Gene Supplementation Therapies for Achromatopsia and Retinitis Pigmentosa. (2018) (4)
Humoral immune response to subretinal AAV8 in non-human primates (2016) (3)
How do patients rate their subjective symptoms after CNGA3 gene therapy: First application of the instrument A3-PRO (2017) (3)
Endolysosomal cation channels point the way towards precision medicine of cancer and infectious diseases. (2022) (3)
Neuropathic and cAMP-induced pain behavior is ameliorated in mice lacking CNGB1 (2020) (3)
In Vitro Evaluation of AAV Vectors for Retinal Gene Therapy. (2019) (3)
AAV-Mediated Gene Therapy Restores Cone System Functions in cpfl5 Mouse, a Model of Human Achromatopsia With CNGA3 Mutation (2008) (2)
Physiological roles of cGMP-gated channels: lessons from mouse models and human channelopathies (2009) (2)
Systematic studies on stabilization of AAV vector formulations by lyophilization. (2022) (2)
High voltage activated calcium channels (1991) (2)
More than meets the eye: The role of microglia in healthy and diseased retina (2022) (2)
The epigenetic mark 5hmC recruits a dynamic set of readers in the retina (2014) (2)
Author response: Selective agonist of TRPML2 reveals direct role in chemokine release from innate immune cells (2018) (2)
Advancing Gene Therapy for PDE6A Retinitis Pigmentosa. (2019) (2)
Exploring Different Serotypes And Promoters In rAAV-mediated Gene Replacement Therapy Of Achromatopsia Type 2 (ACHM2) (2011) (2)
Mutations within the cGMP-binding domain of CNGA1 causing autosomal recessive retinitis pigmentosa in human and animal model (2022) (2)
Connexin 36-dependent Retinal Function in Mice with Specific Rod or Cone Photoreceptor Input (2003) (2)
Genetic Separation Of Rod And Cone-driven Activity In RPE65 Knockout Mice Identifies The Rods As The Source Of Vision In A Form Of Lebers Congenital Amaurosis (2002) (1)
Properties of Rod-Mediated Flicker Assessed in the Cnga3 Mouse Model Lacking Cone Function (2003) (1)
First Gene Supplementation Therapy for CNGA3-linked Achromatopsia (2018) (1)
Genetic deletion of the HCN3 pacemaker channel in mice (2003) (1)
Hyperhydroxymethylation in rd1 retinal degeneration (2014) (1)
Retina Superior Retinal Gene Transfer and Biodistribution Profile of Subretinal Versus Intravitreal Delivery of AAV 8 in Nonhuman Primates (2017) (1)
Gene Supplementation Therapy for CNGA3-Linked Achromatopsia (2017) (1)
Role of 5-hydroxymethylcytosine during postnatal retinal development (2013) (1)
Investigation of the Immunogenicity of Different Types of Aggregates of a Murine Monoclonal Antibody in Mice (2014) (1)
Cyclic nucleotide gated channels. (1999) (1)
Cyclic Nucleotide-Gated and Hyperpolarization-Activated Channels (2009) (1)
Morphological Alterations in the Retina of CNG3-/- / Rho-/- Double Mutant Mice (2003) (1)
High Susceptibility to Non-Alcoholic Fatty Liver Disease in Two-Pore Channel 2-Deficient Mice (2015) (1)
Chapter 185 – Cyclic Nucleotide-Regulated Cation Channels (2010) (1)
Endoplasmic Reticulum Stress-associated Cone Degeneration in Cyclic Nucleotide-gated Channel Deficiency (2012) (1)
Structure and regulation of L-type calcium channels (1992) (1)
Molecular basis of pacemaker current (2000) (1)
Three-dimensional magnetic resonance analysis of extraocular muscles demonstrates gaze-specific contractile shape changes (2012) (1)
MicroRNA-365 regulates human cardiac action potential duration (2022) (1)
Cyclic nucleotide-gated channels – mediators of NO : cGMP (1)
Hif1a inactivation rescues photoreceptor degeneration induced by a chronic hypoxia-like stress (2018) (1)
Stable and Efficient Lentiviral Gene Transfer of eGFP Under the Control of Novel Cone- and Rod-Specific Promoters (2009) (0)
Retinal Degeneration in CNG Channel Deficient Mouse Lines (2005) (0)
The cardiac L-type calcium channel: Structure and its regulation (1992) (0)
Rod Flicker ERG in Mice (2006) (0)
Digenic triallelic inheritance in cone photoreceptor cyclic nucleotide gated channel associated retinopathies (2019) (0)
Molecular structure and functional properties of cardiac pacemaker channels (2001) (0)
Ligand Binding and Gating in HCN 2 Channels (2009) (0)
A Model-Based Approach to Functional Rod-Cone Interaction in the Retina (2008) (0)
Neuronal Tet3-mediated gene expression in the retina (2015) (0)
Flicker ERG Frequency Series at the ISCEV Standard Flash Intensity in Mice (2012) (0)
Reversal of Chemoresistance in Leukemia Cells Using Synthetic Bisbenzylisoquinoline Derivatives (2018) (0)
Contents Vol. 19, 2011 (2011) (0)
Chromatic Flash Electroretinograms in Mice (2005) (0)
Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications (2017) (0)
Implantation of Combined Telemetric ECG and Blood Pressure Transmitters to Determine Spontaneous Baroreflex Sensitivity in Conscious Mice. (2021) (0)
Recovery of ERG Components in the Cngb1-/- Model of RP Following Gene Therapy (2012) (0)
Inhibition of Endoplasmic Reticulum Calcium Channels Reduces Endoplasmic Reticulum Stress and Cone Death in CNG Channel-Deficient Mice (2016) (0)
Preclinical evaluation of rAAV.CNGB1 in the Cngb1 knockout mouse model of retinitis pigmentosa (2018) (0)
Whole-body analysis of TRPML3 (MCOLN3) expression using a GFP-reporter mouse model reveals widespread expression in secretory cells and endocrine glands (2022) (0)
In vivo Analysis of Cone Specific Transgene Expression Using Lentiviral Vectors (2008) (0)
Peripherin-2 and Rom-1 Have Opposing Effects on Rod Outer Segment Targeting of Two Misfolded Peripherin-2 Mutants in Rods (2017) (0)
Characterization of Two-pore Channel 2 (TPCN2)-mediated Ca 2 (cid:1) Currents in Isolated Lysosomes (2020) (0)
Characterization of a cone-specific mouse transgenic line and subsequent cone transplantation in a mouse model of cone-rod dystrophy. (2015) (0)
Abstract 666: The G-protein Regulator Phosducin is Essential for Sympathetic Control of Blood Pressure (2007) (0)
Permeation Properties of Two Pore Channel 2 (TPCN2)-Mediated Ca2+ Currents Recorded from Single Lysosomes (2011) (0)
Preclinical evaluation of rAAV8.CNGA3 in the Cnga3 knockout mouse model of ACHM2 (2017) (0)
Molecular Bases of Neurodegenerative Disorders of the Retina (2017) (0)
Cellular Mechanisms of Cone Defects in Cyclic Nucleotide-Gated Channel Deficiency (2017) (0)
Therapeutic cross-species efficacy of vectors for human gene therapy in achromatopsia type 2 (ACHM2) (2014) (0)
Peripherin-2 and Rom-1 have opposing effects on rod outer segment targeting of retinitis pigmentosa-linked peripherin-2 mutants (2017) (0)
An endo-lysosomal Ca2+ store in cardiomyocytes controlled by OCaR proteins determines fatal tachyarrhythmias (2022) (0)
Assessment of the Absolute Excitatory Level of the Retina by Direct-Current ERG (2009) (0)
Gene augmentation therapy in a large animal model of PDE6A-Retinitis Pigmentosa results in functional and structural rescue for at least 2.5 years. (2020) (0)
cGMP Accumulation Causes Cone Degeneration in CNG Channel Deficiency (2013) (0)
Preclinical evaluation of rAAV8.PDE6A in the Pde6aD670G mutant mouse model of RP43 (2017) (0)
Two-pore channel protein 1 contributes to NAADP triggered acrosome reaction in spermatozoa (2017) (0)
Modulation of gating kinetics of hyperpolarizationactivated cyclic nucleotide-gated (HCN) channels by SRC kinase (2005) (0)
Biology, Pathobiology and Gene Therapy of CNG Channel-Related Retinopathies (2023) (0)
L-type calcium channel structure and function (1996) (0)
Retina Subretinal Injection for Gene Therapy Does Not Cause Clinically Significant Outer Nuclear Layer Thinning in Normal Primate (2017) (0)
Functional Biomarkers For Successful Molecular Therapy Of The Outer Retina In Retinal Degenerations (2013) (0)
cGMP/PKG Signaling Regulation of Endoplasmic Reticulum Calcium Channels in Cyclic Nucleotide-gated Channel-deficient Cones (2018) (0)
Tissue distribution and possible function of the subunits of the L-type calcium channels (1992) (0)
Cyclic nucleotide-regulated channels (CNG) in GtoPdb v.2021.3 (2021) (0)
Gene therapy approaches to restore retinal cGMP channel function (2015) (0)
Endolysosomal Patch Clamping (2020) (0)
Rod and Cone–Specific Components of the ERG b–wave Revealed by Paired–Flash Paradigm (2005) (0)
Evaluation of reconstitution efficiencies of rAAV-dCas9-VPR split-intein protein trans-splicing vectors in retinal cells (2018) (0)
Visual Function in CaV1.4-Deficient Mice (2012) (0)
Nucleotide-gated Channel Deficiency CyclicCone Photoreceptor Degeneration in Endoplasmic Reticulum Stress-associated Molecular Bases of Disease : (2012) (0)
Development of novel AAV variants with superior photoreceptor transduction properties (2017) (0)
Connexin 36 gap junctions are essential for cone–mediated oscillatory potentials in the mouse electroretinogram (ERG) (2004) (0)
Functional Characterization of a Retinitis Pigmentosa-Associated CNGB1 Mutation (G993V) (2008) (0)
CHAPTER 205 – Cyclic Nucleotide-Regulated Cation Channels (2003) (0)
A critical role of HCN1 in the disease progression of retinitis pigmentosa (2015) (0)
New insights into the mechanisms of retinal degeneration due to Phosphodiesterase 6 (PDE6) deficiency (2018) (0)
Quantitative description of murine OCT features based on reflectivity profiles (2014) (0)
The structure of the skeletal muscle calcium channel (1989) (0)
Electrophysiological Evaluation of Novel Blockers of If Current (2009) (0)
A Model for Rod Flicker Electroretinograms in Mice (2007) (0)
Rod Photoreceptor Light Adaptation in a Mouse Model of Achromatopsia Investigated With Paired-Flash ERGs (2002) (0)
Lung emphysema and impaired macrophage elastase clearance in mucolipin 3 deficient mice (2022) (0)
Combined mRNA and miRNA Expression Profiling of the CNGA3-/- Mouse - A Mouse Model of Cone Dystrophies (2008) (0)
cGMP-cGKII signalling contributes to cone photoreceptor degeneration in achromatopsia (2016) (0)
CRISPR/Cas9 and antisense oligonucleotides for therapy of a deep intronic CLRN1 splice mutation (2018) (0)
Recombinant tandem of pore-domains in a Weakly Inward rectifying K+ channel 2 (TWIK2) forms active lysosomal channels (2017) (0)
mRNA trans-splicing dual AAV vectors for (epi)genome editing and gene therapy (2023) (0)
Differential rescue of protein expression and localization of two adRP-linked PRPH2 mutants in rods is mediated by their specific binding characteristics (2016) (0)
Acute Phase and Long-Term Effects of Subretinal Gene Transfer in Mice (2010) (0)
mRNA Expression Profiling of the Cnga3-/- Mouse With Focus on the Dorsal-Ventral Gradient in Retinal Degeneration (2009) (0)
Impact of Photoreceptor Functionality on the Waveform of the Pupil Light Reflex in Mice (2005) (0)
Contributions of Non-Visual Sensory Signals to the Murine Flash ERG (2013) (0)
1057. Successful Gene Therapy for Retinal Degenerations by Lentiviral Gene Transfer (2004) (0)
Function and regulation of the HCN3 channel (2010) (0)
Exploration of the Mechanisms of Cone Photoreceptor Death in the Deficiency of Phosphodiesterase (2013) (0)
Cyclic nucleotide-regulated channels (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database (2019) (0)
Gene replacement therapy for retinal CNG channelopathies (2013) (0)
Inhibition of cGMP/PKG Signaling Suppresses Endoplasmic Reticulum Stress and Alters Inositol Trisphosphate Receptor Activity in CNG Channel Deficiency (2015) (0)
The two-pore channel TPC1 is required for efficient protein processing through early and recycling endosomes (2017) (0)
Gene Expression Alterations in Mouse Retina with Deficiency of Cone Cyclic Nucleotide-gated Channel Subunits CNGA3 and CNGB3 (2013) (0)
Busskamp Responses in Retinitis Pigmentosa Genetic Reactivation of Cone Photoreceptors Restores Visual (2011) (0)
Inhibition of Inositol 1,4,5-Trisphosphate Receptor Activity Reduces Endoplasmic Reticulum Stress and Cone Death in CNG Channel Deficiency (2015) (0)
Differential Disease Profiles of Two Retinitis Pigmentosa Point Mutations in Rhodopsin Correlate with the Mutant Effects on mRNA Splicing (2018) (0)
Analysis of HCN2 and HCN4 knockout mice (2003) (0)
The Structure of the Skeletal and Nonskeletal Muscle Calcium Channel (1989) (0)
Inhibition of Protein Kinase G Activity Improves Cone Survival in Cyclic Nucleotide-gated Channel Deficiency (2014) (0)
Sick Sinus Syndrome in HCN 1-Deficient Mice Running title : (2013) (0)
Gene therapy approaches to restore retinal cGMP channel function (2015) (0)
Altered hippocampal transmission in mice lacking the cone cyclic nucleotide-gated channel CNGA3 (2003) (0)
Endolysosomal two-pore channels: from genes to function (2017) (0)
Author response: Agonist-mediated switching of ion selectivity in TPC2 differentially promotes lysosomal function (2020) (0)
Characterization of neurite outgrowth and ectopic synaptogenesis in response to photoreceptor dysfunction (2012) (0)
High-Voltage Activated Ca2+ Channel (1993) (0)
Afamilyof hyperpolarization-activatedmammaliancation channels (0)

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