Martin D. Brand

Martin D. Brand's AcademicInfluence.com Rankings

Martin D. Brand

Biology

#4498

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#6699

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Cell Biology

#112

World Rank

#117

Historical Rank

biology Degrees

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Biology

Martin D. Brand's Degrees

PhD Cell Biology University of California, Berkeley
Masters Biochemistry Stanford University
Bachelors Biology University of California, Berkeley

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Martin D. Brand's Published Works

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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Assessing mitochondrial dysfunction in cells (2011) (1916)
Topology of Superoxide Production from Different Sites in the Mitochondrial Electron Transport Chain* (2002) (1483)
Superoxide activates mitochondrial uncoupling proteins (2002) (1327)
Mitochondrial superoxide: production, biological effects, and activation of uncoupling proteins. (2004) (991)
The sites and topology of mitochondrial superoxide production (2010) (970)
Physiological functions of the mitochondrial uncoupling proteins UCP2 and UCP3. (2005) (760)
Uncoupling to survive? The role of mitochondrial inefficiency in ageing (2000) (738)
A hierarchy of ATP-consuming processes in mammalian cells. (1995) (718)
Mitochondrial generation of superoxide and hydrogen peroxide as the source of mitochondrial redox signaling. (2016) (661)
Mitochondrial proton and electron leaks. (2010) (628)
Mice overexpressing human uncoupling protein-3 in skeletal muscle are hyperphagic and lean (2000) (611)
A signalling role for 4‐hydroxy‐2‐nonenal in regulation of mitochondrial uncoupling (2003) (582)
Mitochondrial Complex II Can Generate Reactive Oxygen Species at High Rates in Both the Forward and Reverse Reactions* (2012) (519)
Uncoupled and surviving: individual mice with high metabolism have greater mitochondrial uncoupling and live longer (2004) (509)
Prevention of mitochondrial oxidative damage as a therapeutic strategy in diabetes. (2004) (489)
Inhibitors of the Quinone-binding Site Allow Rapid Superoxide Production from Mitochondrial NADH:Ubiquinone Oxidoreductase (Complex I)* (2004) (461)
The causes and functions of mitochondrial proton leak. (1994) (457)
Superoxide production by NADH:ubiquinone oxidoreductase (complex I) depends on the pH gradient across the mitochondrial inner membrane. (2004) (439)
Sites of reactive oxygen species generation by mitochondria oxidizing different substrates☆ (2013) (431)
High Throughput Microplate Respiratory Measurements Using Minimal Quantities Of Isolated Mitochondria (2011) (416)
Superoxide Activates Mitochondrial Uncoupling Protein 2 from the Matrix Side (2002) (403)
The regulation and physiology of mitochondrial proton leak. (2011) (376)
The efficiency and plasticity of mitochondrial energy transduction. (2005) (363)
The basal proton conductance of mitochondria depends on adenine nucleotide translocase content. (2005) (360)
Contribution of mitochondrial proton leak to skeletal muscle respiration and to standard metabolic rate. (1996) (308)
Quantitative Microplate-Based Respirometry with Correction for Oxygen Diffusion (2009) (302)
Reactive oxygen species production by mitochondria. (2009) (300)
Superoxide and hydrogen peroxide production by Drosophila mitochondria. (2003) (296)
Superoxide Activates Uncoupling Proteins by Generating Carbon-centered Radicals and Initiating Lipid Peroxidation (2003) (296)
Mitochondrial matrix reactive oxygen species production is very sensitive to mild uncoupling. (2003) (280)
Bioenergetics of immune functions: fundamental and therapeutic aspects. (2000) (277)
Evolution of energy metabolism. Proton permeability of the inner membrane of liver mitochondria is greater in a mammal than in a reptile. (1991) (276)
Production of superoxide and hydrogen peroxide from specific mitochondrial sites under different bioenergetic conditions (2017) (274)
Quantifying intracellular rates of glycolytic and oxidative ATP production and consumption using extracellular flux measurements (2017) (273)
The contributions of respiration and glycolysis to extracellular acid production. (2015) (256)
Analysis of the control of respiration rate, phosphorylation rate, proton leak rate and protonmotive force in isolated mitochondria using the 'top-down' approach of metabolic control theory. (1990) (253)
The proton leak across the mitochondrial inner membrane. (1990) (252)
Low rates of hydrogen peroxide production by isolated heart mitochondria associate with long maximum lifespan in vertebrate homeotherms (2007) (250)
The 2-Oxoacid Dehydrogenase Complexes in Mitochondria Can Produce Superoxide/Hydrogen Peroxide at Much Higher Rates Than Complex I* (2014) (249)
Characteristics of mitochondrial proton leak and control of oxidative phosphorylation in the major oxygen-consuming tissues of the rat. (1994) (248)
Contribution of mitochondrial proton leak to respiration rate in working skeletal muscle and liver and to SMR. (1999) (245)
Body mass dependence of H+ leak in mitochondria and its relevance to metabolic rate (1993) (239)
UCP2 and UCP3 rise in starved rat skeletal muscle but mitochondrial proton conductance is unchanged (1999) (237)
The proton permeability of the inner membrane of liver mitochondria from ectothermic and endothermic vertebrates and from obese rats: correlations with standard metabolic rate and phospholipid fatty acid composition. (1998) (235)
Sites of Superoxide and Hydrogen Peroxide Production by Muscle Mitochondria Assessed ex Vivo under Conditions Mimicking Rest and Exercise* (2014) (235)
Mitochondrial uncoupling as a target for drug development for the treatment of obesity (2001) (230)
The on-off switches of the mitochondrial uncoupling proteins. (2010) (223)
The Physiological Significance of Mitochondrial Proton Leak in Animal Cells and Tissues (1997) (219)
Characterization of the human, mouse and rat PGC1 beta (peroxisome-proliferator-activated receptor-gamma co-activator 1 beta) gene in vitro and in vivo. (2003) (218)
The Basal Proton Conductance of Skeletal Muscle Mitochondria from Transgenic Mice Overexpressing or Lacking Uncoupling Protein-3* (2002) (217)
CONTROL OF ELECTRON FLUX THROUGH THE RESPIRATORY CHAIN IN MITOCHONDRIA AND CELLS (1987) (217)
Allometry of mitochondrial proton leak: influence of membrane surface area and fatty acid composition. (1996) (207)
A 'top-down' approach to the determination of control coefficients in metabolic control theory. (1990) (192)
Mitochondrial superoxide and aging: uncoupling-protein activity and superoxide production. (2004) (186)
Oxidative damage and phospholipid fatty acyl composition in skeletal muscle mitochondria from mice underexpressing or overexpressing uncoupling protein 3. (2002) (183)
The quantitative contributions of mitochondrial proton leak and ATP turnover reactions to the changed respiration rates of hepatocytes from rats of different thyroid status. (1993) (175)
The Role of Mitochondrially Derived ATP in Synaptic Vesicle Recycling*♦ (2015) (173)
Evidence for Two Sites of Superoxide Production by Mitochondrial NADH-Ubiquinone Oxidoreductase (Complex I)* (2011) (171)
Control of respiration and oxidative phosphorylation in isolated rat liver cells. (1990) (171)
Non-ohmic proton conductance of the mitochondrial inner membrane in hepatocytes. (1990) (170)
Mitochondrial proton leak and the uncoupling protein 1 homologues. (2001) (165)
A reduction in ATP demand and mitochondrial activity with neural differentiation of human embryonic stem cells (2011) (159)
The reactions catalysed by the mitochondrial uncoupling proteins UCP2 and UCP3. (2005) (156)
Quantitative measurement of mitochondrial membrane potential in cultured cells: calcium‐induced de‐ and hyperpolarization of neuronal mitochondria (2012) (154)
The significance and mechanism of mitochondrial proton conductance (1999) (153)
Mitochondria as ATP consumers: cellular treason in anoxia. (2000) (150)
Equivalent doses and relative drug potencies for non-genomic glucocorticoid effects: a novel glucocorticoid hierarchy. (1999) (149)
Mitochondrial uncoupling and lifespan (2010) (148)
The Mechanism of Superoxide Production by the Antimycin-inhibited Mitochondrial Q-cycle* (2011) (147)
Signaling takes a breath--new quantitative perspectives on bioenergetics and signal transduction. (2001) (145)
Altered relationship between protonmotive force and respiration rate in non-phosphorylating liver mitochondria isolated from rats of different thyroid hormone status. (1988) (145)
Proton conductance and fatty acyl composition of liver mitochondria correlates with body mass in birds. (2003) (143)
Artifactual uncoupling by uncoupling protein 3 in yeast mitochondria at the concentrations found in mouse and rat skeletal-muscle mitochondria. (2002) (140)
Superoxide Stimulates a Proton Leak in Potato Mitochondria That Is Related to the Activity of Uncoupling Protein* (2003) (139)
Suppressors of Superoxide-H2O2 Production at Site IQ of Mitochondrial Complex I Protect against Stem Cell Hyperplasia and Ischemia-Reperfusion Injury. (2016) (136)
Suppressors of superoxide production from mitochondrial complex III (2015) (135)
Production of endogenous matrix superoxide from mitochondrial complex I leads to activation of uncoupling protein 3 (2004) (131)
The regulation and turnover of mitochondrial uncoupling proteins. (2010) (131)
Native rates of superoxide production from multiple sites in isolated mitochondria measured using endogenous reporters. (2012) (128)
A Refined Analysis of Superoxide Production by Mitochondrial sn-Glycerol 3-Phosphate Dehydrogenase* (2012) (128)
The contribution of the leak of protons across the mitochondrial inner membrane to standard metabolic rate. (1990) (124)
Causes of differences in respiration rate of hepatocytes from mammals of different body mass. (1995) (123)
Mitochondrial uncouplers with an extraordinary dynamic range. (2007) (122)
The efficiency of cellular energy transduction and its implications for obesity. (2008) (121)
Uncoupling protein-3 lowers reactive oxygen species production in isolated mitochondria. (2010) (119)
Regulation analysis of energy metabolism. (1997) (117)
Top down metabolic control analysis. (1996) (117)
Degradation of an intramitochondrial protein by the cytosolic proteasome (2010) (115)
Control of the effective P/O ratio of oxidative phosphorylation in liver mitochondria and hepatocytes. (1993) (114)
A mitochondrial uncoupling artifact can be caused by expression of uncoupling protein 1 in yeast. (2001) (112)
The topology of superoxide production by complex III and glycerol 3-phosphate dehydrogenase in Drosophila mitochondria. (2005) (108)
Uncoupling protein and ATP/ADP carrier increase mitochondrial proton conductance after cold adaptation of king penguins (2004) (108)
Diphenyleneiodonium acutely inhibits reactive oxygen species production by mitochondrial complex I during reverse, but not forward electron transport. (2008) (107)
Plasticity of Oxidative Metabolism in Variable Climates: Molecular Mechanisms* (2010) (106)
The Proton Permeability of Liposomes Made from Mitochondrial Inner Membrane Phospholipids: Comparison with Isolated Mitochondria (1997) (105)
The mechanism of the increase in mitochondrial proton permeability induced by thyroid hormones. (1992) (105)
Top-down control analysis of ATP turnover, glycolysis and oxidative phosphorylation in rat hepatocytes. (1999) (105)
Re-evaluation of the H+/site ratio of mitochondrial electron transport with the oxygen pulse technique. (1976) (105)
Determining Maximum Glycolytic Capacity Using Extracellular Flux Measurements (2016) (104)
UCPs — unlikely calcium porters (2008) (102)
Physiological Levels of Mammalian Uncoupling Protein 2 Do Not Uncouple Yeast Mitochondria* (2001) (100)
Control of respiration in non-phosphorylating mitochondria is shared between the proton leak and the respiratory chain. (1988) (100)
The role of mitochondrial function and cellular bioenergetics in ageing and disease (2013) (99)
Lack of Correlation between Mitochondrial Reactive Oxygen Species Production and Life Span in Drosophila (2004) (96)
Control and kinetic analysis of ischemia-damaged heart mitochondria: which parts of the oxidative phosphorylation system are affected by ischemia? (1995) (95)
Transcript and metabolite analysis of the effects of tamoxifen in rat liver reveals inhibition of fatty acid synthesis in the presence of hepatic steatosis (2005) (95)
Sites of superoxide and hydrogen peroxide production during fatty acid oxidation in rat skeletal muscle mitochondria. (2013) (93)
Experimental discrimination between proton leak and redox slip during mitochondrial electron transport. (1994) (92)
Uncoupling protein-2 contributes significantly to high mitochondrial proton leak in INS-1E insulinoma cells and attenuates glucose-stimulated insulin secretion. (2008) (91)
Thermodynamic control of electron flux through mitochondrial cytochrome bc1 complex. (1985) (90)
Tissue-specific depression of mitochondrial proton leak and substrate oxidation in hibernating arctic ground squirrels. (2003) (90)
The effect of metabolic depression on proton leak rate in mitochondria from hibernating frogs. (2000) (89)
Inhibition of mitochondrial pyruvate transport by phenylpyruvate and α-ketoisocaproate (1974) (87)
Changes in permeability to protons and other cations at high proton motive force in rat liver mitochondria. (1986) (83)
Flight activity, mortality rates, and lipoxidative damage in Drosophila. (2006) (82)
Calcium regulation of oxidative phosphorylation in rat skeletal muscle mitochondria. (2000) (81)
Proton/electron stoichiometry of mitochondrial complex I estimated from the equilibrium thermodynamic force ratio. (1988) (80)
Factors determining the plasma-membrane potential of lymphocytes. (1982) (80)
Primary causes of decreased mitochondrial oxygen consumption during metabolic depression in snail cells. (2002) (79)
Uncoupling protein-2 attenuates glucose-stimulated insulin secretion in INS-1E insulinoma cells by lowering mitochondrial reactive oxygen species (2011) (79)
Processes contributing to metabolic depression in hepatopancreas cells from the snail Helix aspersa. (2000) (79)
Evaluation of the H+/site ratio of mitochondrial electron transport from rate measurements. (1976) (79)
On the nature of the mitochondrial proton leak. (1991) (78)
Uncoupling protein 2 from carp and zebrafish, ectothermic vertebrates. (1999) (78)
The proton permeability of liposomes made from mitochondrial inner membrane phospholipids: no effect of fatty acid composition. (1997) (78)
Energization-dependent endogenous activation of proton conductance in skeletal muscle mitochondria (2008) (77)
Measurement of proton leak and electron leak in isolated mitochondria. (2012) (77)
On the role of uncoupling protein-2 in pancreatic beta cells. (2008) (76)
Hydrogen peroxide efflux from muscle mitochondria underestimates matrix superoxide production – a correction using glutathione depletion (2010) (76)
The nature of the calcium ion efflux induced in rat liver mitochondria by the oxidation of endogenous nicotinamide nucleotides. (1980) (75)
The mechanism of stimulation of respiration by fatty acids in isolated hepatocytes. (1990) (74)
Mitochondrial Proton Leak and the Uncoupling Proteins (1999) (74)
Glucagon activates mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase in vivo by decreasing the extent of succinylation of the enzyme. (1990) (74)
Biomarkers of aging in Drosophila (2010) (74)
Measurement and Analysis of Extracellular Acid Production to Determine Glycolytic Rate (2015) (73)
Functional characterisation of UCP1 in the common carp: uncoupling activity in liver mitochondria and cold-induced expression in the brain (2007) (72)
Liposomes from mammalian liver mitochondria are more polyunsaturated and leakier to protons than those from reptiles. (1994) (71)
Stimulation of mitochondrial proton conductance by hydroxynonenal requires a high membrane potential (2008) (71)
Experimental assessment of bioenergetic differences caused by the common European mitochondrial DNA haplogroups H and T (2008) (71)
Impact of endotoxin on UCP homolog mRNA abundance, thermoregulation, and mitochondrial proton leak kinetics. (2000) (71)
Hydroxynonenal and uncoupling proteins: A model for protection against oxidative damage (2005) (70)
Were inefficient mitochondrial haplogroups selected during migrations of modern humans? A test using modular kinetic analysis of coupling in mitochondria from cybrid cell lines. (2007) (70)
Proton leak in hepatocytes and liver mitochondria from archosaurs (crocodiles) and allometric relationships for ectotherms (2002) (69)
Cellular oxygen consumption depends on body mass. (1995) (68)
Nonsteroidal antiinflammatory drugs and a selective cyclooxygenase 2 inhibitor uncouple mitochondria in intact cells. (2003) (68)
Uncoupling protein-1 (UCP1) contributes to the basal proton conductance of brown adipose tissue mitochondria (2009) (67)
The stoichiometry of the exchange catalysed by the mitochondrial calcium/sodium antiporter. (1985) (67)
Stoichiometric relationship between energy-dependent proton ejection and electron transport in mitochondria. (1976) (66)
The determination and analysis of site-specific rates of mitochondrial reactive oxygen species production. (2013) (66)
Stoichiometry of H+ ejection during respiration-dependent accumulation of Ca2+ by rat liver mitochondria. (1976) (66)
Dependence of brown adipose tissue function on CD36-mediated coenzyme Q uptake. (2015) (65)
Low complex I content explains the low hydrogen peroxide production rate of heart mitochondria from the long‐lived pigeon, Columba livia (2010) (65)
Targeting Dinitrophenol to Mitochondria: Limitations to the Development of a Self-limiting Mitochondrial Protonophore (2006) (65)
H+/ATP ratio during ATP hydrolysis by mitochondria: modification of the chemiosmotic theory. (1977) (64)
Inhibitors of ROS production by the ubiquinone-binding site of mitochondrial complex I identified by chemical screening. (2013) (64)
Thyroid-hormone control of state-3 respiration in isolated rat liver mitochondria. (1990) (63)
Respiration rate of hepatocytes varies with body mass in birds (2004) (62)
Osteoblast‐like MC3T3‐E1 Cells Prefer Glycolysis for ATP Production but Adipocyte‐like 3T3‐L1 Cells Prefer Oxidative Phosphorylation (2018) (62)
Leptin-mediated changes in hepatic mitochondrial metabolism, structure, and protein levels (2009) (62)
Early plasma-membrane-potential changes during stimulation of lymphocytes by concanavalin A. (1983) (61)
Mitochondrial and cytosolic sources of hydrogen peroxide in resting C2C12 myoblasts (2019) (61)
Stronger control of ATP/ADP by proton leak in pancreatic beta-cells than skeletal muscle mitochondria. (2006) (60)
Effects of thyroid hormones on oxidative phosphorylation. (1993) (60)
Superoxide activates a GDP-sensitive proton conductance in skeletal muscle mitochondria from king penguin (Aptenodytes patagonicus). (2003) (60)
Production of superoxide/H2O2 by dihydroorotate dehydrogenase in rat skeletal muscle mitochondria. (2014) (59)
Variable stoichiometry of proton pumping by the mitochondrial respiratory chain (1987) (57)
Sources of superoxide/H2O2 during mitochondrial proline oxidation (2014) (57)
Rapid turnover of mitochondrial uncoupling protein 3. (2010) (56)
Proton leak and control of oxidative phosphorylation in perfused, resting rat skeletal muscle. (1996) (56)
Measuring mitochondrial bioenergetics in INS-1E insulinoma cells. (2009) (55)
The contribution of ATP turnover by the Na+/K+-ATPase to the rate of respiration of hepatocytes. Effects of thyroid status and fatty acids. (1989) (55)
Uncoupling protein 3 protects aconitase against inactivation in isolated skeletal muscle mitochondria. (2005) (55)
The effect of insulin on plasma-membrane and mitochondrial-membrane potentials in isolated fat-cells. (1981) (55)
Internal regulation of ATP turnover, glycolysis and oxidative phosphorylation in rat hepatocytes. (1999) (55)
Methylprednisolone inhibits uptake of Ca2+ and Na+ ions into concanavalin A-stimulated thymocytes. (1997) (55)
Effect of 3,5-di-iodo-L-thyronine on the mitochondrial energy-transduction apparatus. (1998) (54)
Novel uncoupling proteins. (2007) (54)
Unequal charge separation by different coupling spans of the mitochondrial electron transport chain (1978) (53)
4-Hydroxy-2-nonenal and uncoupling proteins: an approach for regulation of mitochondrial ROS production (2007) (53)
Ubiquinone is not required for proton conductance by uncoupling protein 1 in yeast mitochondria. (2004) (53)
Treatment of rats with glucagon or mannoheptulose increases mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase activity and decreases succinyl-CoA content in liver. (1989) (52)
Mitochondrial proton conductance and H+/O ratio are independent of electron transport rate in isolated hepatocytes. (1995) (52)
Coenzyme Q induces GDP-sensitive proton conductance in kidney mitochondria. (2001) (50)
Walking the oxidative stress tightrope: a perspective from the naked mole-rat, the longest-living rodent. (2011) (50)
The effects of methylprednisolone on oxidative phosphorylation in Concanavalin-A-stimulated thymocytes. Top-down elasticity analysis and control analysis. (1994) (50)
Intrinsic Bioenergetic Properties and Stress Sensitivity of Dopaminergic Synaptosomes (2011) (49)
Choline transport into rat liver mitochondria. Characterization and kinetics of a specific transporter. (1992) (49)
High membrane potential promotes alkenal-induced mitochondrial uncoupling and influences adenine nucleotide translocase conformation (2008) (48)
The mechanism of the stimulation of state 4 respiration by cadmium in patato tuber (Solanum tuberosum) mitochondria (1995) (48)
The control of electron flux through cytochrome oxidase. (1986) (48)
Localisation of the sites of action of cadmium on oxidative phosphorylation in potato tuber mitochondria using top-down elasticity analysis. (1994) (47)
Effects of magnesium and nucleotides on the proton conductance of rat skeletal-muscle mitochondria. (2000) (47)
Top-down elasticity analysis and its application to energy metabolism in isolated mitochondria and intact cells (1998) (46)
The stoichiometry of charge translocation by cytochrome oxidase and the cytochrome bc1 complex of mitochondria at high membrane potential. (1988) (46)
A Model of the Proton Translocation Mechanism of Complex I* (2011) (45)
Compromised Mitochondrial Fatty Acid Synthesis in Transgenic Mice Results in Defective Protein Lipoylation and Energy Disequilibrium (2012) (45)
Proportional activation coefficients during stimulation of oxidative phosphorylation by lactate and pyruvate or by vasopressin. (1995) (45)
Fatty Acids Change the Conformation of Uncoupling Protein 1 (UCP1)* (2012) (44)
Dynamic regulation of uncoupling protein 2 content in INS-1E insulinoma cells (2008) (44)
Production of superoxide/hydrogen peroxide by the mitochondrial 2-oxoadipate dehydrogenase complex. (2016) (44)
Novel Inhibitors of Mitochondrial sn-Glycerol 3-phosphate Dehydrogenase (2014) (43)
Effect of protonmotive force on the relative proton stoichiometries of the mitochondrial proton pumps. (1991) (43)
Glutamate and aspartate transport in rat brain mitochondria. (1974) (42)
Membrane potential of mitochondria in intact lymphocytes during early mitogenic stimulation. (1984) (42)
Hypothyroidism in rats decreases mitochondrial inner membrane cation permeability (1989) (42)
Effects of the mitogen concanavalin A on pathways of thymocyte energy metabolism. (1999) (40)
Synergy of fatty acid and reactive alkenal activation of proton conductance through uncoupling protein 1 in mitochondria. (2006) (40)
Research on mitochondria and aging, 2006–2007 (2007) (40)
Plasma Membrane Potential Oscillations in Insulin Secreting Ins-1 832/13 Cells Do Not Require Glycolysis and Are Not Initiated by Fluctuations in Mitochondrial Bioenergetics* (2012) (40)
The intracellular calcium antagonist TMB-8 [8-(NN-diethylamino)octyl-3,4,5-trimethoxybenzoate] inhibits mitochondrial ATP production in rat thymocytes. (1984) (39)
Intrinsic metabolic depression in cells isolated from the hepatopancreas of estivating snails (2000) (39)
Does Any Yeast Mitochondrial Carrier Have a Native Uncoupling Protein Function? (2002) (39)
Membrane-potential-dependent changes in the stoichiometry of charge translocation by the mitochondrial electron transport chain. (1988) (38)
Superstoichiometric Ca2+ uptake supported by hydrolysis of endogenous ATP in rat liver mitochondria. (1975) (38)
AMP decreases the efficiency of skeletal-muscle mitochondria (2000) (38)
Concanavalin A causes an increase in sodium permeability and intracellular sodium content of pig lymphocytes. (1983) (38)
Hyperthyroidism stimulates mitochondrial proton leak and ATP turnover in rat hepatocytes but does not change the overall kinetics of substrate oxidation reactions. (1994) (38)
Mitochondrial proton leak kinetics and relationship with feed efficiency within a single genetic line of male broilers. (2009) (37)
Quantitative determination of the regulation of oxidative phosphorylation by cadmium in potato tuber mitochondria. (1994) (37)
The responses of rat hepatocytes to glucagon and adrenaline. Application of quantified elasticity analysis. (2001) (37)
The effect of dietary restriction on mitochondrial protein density and flight muscle mitochondrial morphology in Drosophila. (2006) (37)
Characterisation of the control of respiration in potato tuber mitochondria using the top-down approach of metabolic control analysis. (1992) (37)
Control of hepatic mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase during the foetal/neonatal transition, suckling and weaning in the rat. (1991) (36)
Riding the tiger – physiological and pathological effects of superoxide and hydrogen peroxide generated in the mitochondrial matrix (2020) (36)
Use of Top-Down Elasticity Analysis to Identify Sites of Thyroid Hormone-Induced Thermogenesis (1995) (35)
Top-down control analysis of systems with more than one common intermediate. (1995) (33)
Electroneutral efflux of Ca2+ from liver mitochondria. (1985) (33)
Dissociation of superoxide production by mitochondrial complex I from NAD(P)H redox state (2008) (33)
Effects of cadmium on the control and internal regulation of oxidative phosphorylation in potato tuber mitochondria. (1994) (32)
The use of site-specific suppressors to measure the relative contributions of different mitochondrial sites to skeletal muscle superoxide and hydrogen peroxide production (2019) (32)
Hypothyroidism in rats does not lower mitochondrial ADP/O and H+/O ratios. (1988) (31)
Special issue on dietary restriction: Dietary restriction, longevity and ageing—the current state of our knowledge and ignorance (2005) (31)
Effects of methylprednisolone on the energy metabolism of quiescent and conA-stimulated thymocytes of the rat (1993) (31)
ConA induced changes in energy metabolism of rat thymocytes (1992) (30)
Mitochondrial bioenergetics and neuronal survival modelled in primary neuronal culture and isolated nerve terminals (2015) (30)
Stimulation of the respiration rate of rat liver mitochondria by sub-micromolar concentrations of extramitochondrial Ca2+. (1987) (30)
Cold-induced alterations of phospholipid fatty acyl composition in brown adipose tissue mitochondria are independent of uncoupling protein-1. (2007) (30)
Control of oxidative phosphorylation in liver mitochondria and hepatocytes. (1993) (29)
No Consistent Bioenergetic Defects in Presynaptic Nerve Terminals Isolated from Mouse Models of Alzheimer's Disease (2012) (29)
Errors associated with metabolic control analysis. Application Of Monte-Carlo simulation of experimental data. (1998) (29)
Fluorocitrate inhibition of aconitate hydratase and the tricarboxylate carrier of rat liver mitochondria. (1973) (29)
Mechanism of activation of pyruvate dehydrogenase by mitogens in pig lymphocytes. (1983) (29)
The stoicheiometric relationships between electron transport, proton translocation and adenosine triphosphate synthesis and hydrolysis in mitochondria. (1977) (29)
Stable nuclear expression of ATP8 and ATP6 genes rescues a mtDNA Complex V null mutant (2016) (28)
A top-down control analysis in isolated rat liver mitochondria: can the 3-hydroxy-3-methylglutaryl-CoA pathway be rate-controlling for ketogenesis? (1993) (28)
Simplifying metabolic complexity. (2001) (27)
Proton translocation by the mitochondrial cytochrome b-c1 complex is inhibited by NN'-dicyclohexylcarbodi-imide. (1982) (27)
Nucleotide binding to human uncoupling protein-2 refolded from bacterial inclusion bodies. (2002) (27)
Quantitation of signal transduction (2000) (26)
Quantifying elasticity analysis: how external effectors cause changes to metabolic systems. (1999) (26)
Oxaloacetate- and acetoacetate-induced calcium efflux from mitochondria occurs by reversal of the uptake pathway. (1982) (25)
Mitochondrial uncoupling protein 2 in pancreatic β‐cells (2010) (25)
Stimulation of the electron transport chain in mitochondria isolated from rats treated with mannoheptulose or glucagon. (1990) (25)
Valinomycin can depolarize mitochondria in intact lymphocytes without increasing plasma membrane potassium fluxes (1982) (25)
AMP decreases the efficiency of skeletal-muscle mitochondria. (2000) (24)
Stimulation of respiration by mitogens in rat thymocytes is independent of mitochondrial calcium. (1988) (24)
Therapeutically targeting lymphocyte energy metabolism by high-dose glucocorticoids. (2000) (24)
The choline transporter is the major site of control of choline oxidation in isolated rat liver mitochondria (1993) (24)
Metabolic Downregulation and Inhibition of Carbohydrate Catabolism during Diapause in Embryos of Artemia franciscana (2012) (24)
Dysregulation of glucose homeostasis in nicotinamide nucleotide transhydrogenase knockout mice is independent of uncoupling protein 2 (2009) (23)
A Prototypical Small-Molecule Modulator Uncouples Mitochondria in Response to Endogenous Hydrogen Peroxide Production (2013) (23)
Expression of human uncoupling protein-3 in Drosophila insulin-producing cells increases insulin-like peptide (DILP) levels and shortens lifespan (2009) (23)
Steady-state H+/O stoichiometry of liver mitochondria. (1981) (23)
The sum of flux control coefficients in the electron-transport chain of mitochondria. (1994) (22)
Regulation of oxidative phosphorylation in plant mitochondria. (1993) (21)
Specific inhibition by synthetic analogs of pyruvate reveals that the pyruvate dehydrogenase reaction is essential for metabolism and viability of glioblastoma cells (2015) (21)
Chemical Modification of the Mitochodrial bc1 by N,N′ -Dicyclohexylcarbodiimide Inhibits Proton Translocation (1983) (21)
ConA induced changes in energy metabolism of rat thymocytes (1992) (20)
25.1. Mitochondria and Reactive Oxygen Species (2007) (20)
Measurement of the Absolute Magnitude and Time Courses of Mitochondrial Membrane Potential in Primary and Clonal Pancreatic Beta-Cells (2016) (19)
Mitochondrial Proton Conductance, Standard Metabolic Rate and Metabolic Depression (2000) (19)
Control analysis of energy metabolism in mitochondria. (1995) (19)
Effects of glucagon and Na+ on the control of extramitochondrial free Ca2+ concentration by mitochondrial from liver and heart. (1980) (19)
S1QELs suppress mitochondrial superoxide/hydrogen peroxide production from site IQ without inhibiting reverse electron flow through Complex I. (2019) (19)
Choline transport into rat liver mitochondria. (1992) (19)
Production of superoxide and hydrogen peroxide in the mitochondrial matrix is dominated by site IQ of complex I in diverse cell lines (2020) (19)
Changes in the hepatic mitochondrial respiratory system in the transition from weaning to adulthood in rats. (1998) (18)
Caged mitochondrial uncouplers that are released in response to hydrogen peroxide (2010) (18)
A HIERARCHY OF ATP-CONSUMING PROCESSES (1996) (17)
Generation of superoxide and hydrogen peroxide by side reactions of mitochondrial 2-oxoacid dehydrogenase complexes in isolation and in cells (2018) (17)
A quantitative assessment of the use of 36Cl- distribution to measure plasma membrane potential in isolated hepatocytes. (1989) (17)
Characteristics of the turnover of uncoupling protein 3 by the ubiquitin proteasome system in isolated mitochondria. (2011) (17)
Inhibition of mitochondrial pyruvate transport by phenylpyruvate and alpha-ketoisocaproate. (1974) (17)
The role of mitochondria in longevity and healthspan (2014) (16)
Comparison of Mitochondrial Reactive Oxygen Species Production of Ectothermic and Endothermic Fish Muscle (2017) (16)
Control analysis of systems with reaction blocks that 'cross-talk'. (1998) (15)
Mitochondrial ROS production (2007) (15)
Use of S1QELs and S3QELs to link mitochondrial sites of superoxide and hydrogen peroxide generation to physiological and pathological outcomes. (2019) (15)
The isolation of lymphocyte mitochondria and their regulation of extramitochondrial free Ca2+ concentration. (1982) (15)
Mechanisms of Mitochondrial Free Radical Production and their Relationship to the Aging Process (2011) (15)
Characterization of betaine efflux from rat liver mitochondria. (1993) (14)
Mitogenic stimulation transiently increases the exchangeable mitochondrial calcium pool in rat thymocytes. (1987) (13)
Relationship between membrane potential and respiration rate in isolated liver mitochondria from rats fed an energy dense diet (1996) (13)
The effect of chloroform on mitochondrial energy transduction. (1996) (13)
Structure and Function of Mitochondria in Hepatopancreas Cells from Metabolically Depressed Snails (2002) (13)
PERMEABILITY OF MITOCHONDRIA FROM RAT BRAIN AND RAT LIVER TO GABA (1974) (13)
Positive Feedback Amplifies the Response of Mitochondrial Membrane Potential to Glucose Concentration in Clonal Pancreatic Beta Cells. (2017) (13)
Approximate yield of ATP from glucose, designed by donald nicholson: Commentary (2003) (12)
Superoxide produced by mitochondrial site IQ inactivates cardiac succinate dehydrogenase and induces hepatic steatosis in Sod2 knockout mice. (2021) (12)
Cardiolipin deficiency in Barth syndrome is not associated with increased superoxide/H2O2 production in heart and skeletal muscle mitochondria (2020) (12)
The mechanism of stimulation of respiration in isolated hepatocytes from rats fed an energy dense diet (1996) (11)
Exploiting Mitochondria In Vivo as Chemical Reaction Chambers Dependent on Membrane Potential. (2016) (11)
The mechanism of Ca2+ stimulation of citrulline and N-acetylglutamate synthesis by mitochondria. (1990) (11)
Not all mitochondrial carrier proteins support permeability transition pore formation: no involvement of uncoupling protein 1 (2009) (11)
Molecular Properties of Purified Human Uncoupling Protein 2 Refolded from Bacterial Inclusion Bodies (2003) (10)
Thermodynamic limits to the stoichiometry of H+ pumping by mitochondrial cytochrome oxidase (1985) (10)
Control of acetoacetate production from exogenous palmitoyl-CoA in isolated rat liver mitochondria. (1989) (10)
Quantifying intracellular rates of glycolytic and oxidative ATP production and consumption using extracellular flux measurements (2018) (9)
Measurement of Proton Leak in Isolated Mitochondria. (2018) (9)
Sub-micromolar concentrations of extramitochondrial Ca2+ stimulate the rate of citrulline synthesis by rat liver mitochondria. (1989) (9)
Determination of the H+/site and Ca2+/site ratios of mitochondrial electron transport. (1979) (9)
Apoptosis and the laws of thermodynamics (2000) (9)
Contribution of mitochondrial proton leak to respiration rate in working skeletal muscle and liver and to SMR. (1999) (9)
Stoicheiometry of charge and proton translocation in mitochondria: steady-state measurement of charge/O and P/O ratios. (1979) (9)
Assessing mitochondrial dysfunction in cells (2011) (8)
Mechanism of the stimulation of respiration by added substrate in hepatocytes (1986) (8)
Control Analysis of DNA Microarray Expression Data (2004) (7)
Thermodynamic and steady-state-kinetic investigation of the effect of NN'-dicyclohexylcarbodi-imide on H+ translocation by the mitochondrial cytochrome bc1 complex. (1985) (7)
Mitochondrial proton leak in metabolic depression (2000) (6)
Measurement of the intramitochondrial PO ratio (1979) (6)
Analysing microarray data using modular regulation analysis (2004) (6)
Size changes of phosphodiesterase in bovine rod outer segments on illumination. (1983) (6)
Substrate dependence of the relationship between membrane potential and respiration rate in mitochondria (1986) (5)
1 EVIDENCE FOR TWO SITES OF SUPEROXIDE PRODUCTION BY MITOCHONDRIAL NADH-Q OXIDOREDUCTASE ( COMPLEX I ) * (2011) (5)
Apparent variation in mitochondrial H+/2e caused by Mg2+ (1985) (4)
Rhodopsin in the disc membrane is a monomer (1983) (4)
Plate-Based Measurement of Respiration by Isolated Mitochondria. (2018) (4)
Measuring mitochondrial uncoupling protein-2 level and activity in insulinoma cells. (2013) (4)
The H+/site ratio of mitochondrial electron transport (1976) (4)
The Whys and Hows of Calculating Total Cellular ATP Production Rate (2019) (4)
Chapter 20 – Control Analysis of Metabolic Depression (2002) (4)
S3QELs protect against diet‐induced intestinal barrier dysfunction (2021) (4)
A new steady-state method for investigating mitochondrial proton transport [proceedings]. (1979) (4)
Controlled power: how biology manages succinate-driven energy release (2021) (4)
Short sequence-paper Uncoupling protein 2 from carp and zebra¢sh, ectothermic vertebrates (1999) (3)
Light changes the membrane potential and ion balances of retinal rod disks (1985) (3)
Analyzing microgram quantities of isolated mitochondria in the XF24 Analyzer (2012) (3)
Target size analysis of rhodopsin in retinal rod disk membranes. (1984) (3)
PATHWAYS AND STOICHIOMETRY OF H + AND Ca 2+ TRANSPORT COUPLED TO ELECTRON TRANSPORT (1976) (3)
The Stoichiometric Coupling of H + Efflux During Electron Transport to H + Influx During ATP Synthesis by Mitochondria (1977) (3)
Glucagon increases mitochondrial 3-hydroxy-3-methylglutaryl-coenzyme A synthase activity in vivo by desuccinylating the enzyme (1989) (2)
Plate-Based Measurement of Superoxide and Hydrogen Peroxide Production by Isolated Mitochondria. (2018) (2)
Some properties of rat liver mitochondria with low Ca2+ content (1986) (2)
Pathways of Ca2+ efflux from liver and heart mitochondria (1985) (2)
A critical assessment of the role of creatine in brown adipose tissue thermogenesis (2023) (1)
Measurement of the intramitochondrial P/O ratio. (1979) (1)
49 - Lack of Oxidative Stress in a Mouse Neural Stem Cell Model of Huntington's Disease (2015) (1)
Regulation of Energy Metabolism in Hepatocytes (2000) (1)
The nature of betaine efflux from rat liver mitochondria. (1992) (1)
3-Hydroxy-3-methylglutaryl coenzyme A synthase activity in rat liver increases with increased ketogenesis (1987) (1)
Mannoheptulose and glucagon treatment of fed rats stimulates 3-hydroxy-3-methylglutaryl-CoA synthase activity in rat liver mitochondria by desuccinylation of the enzyme (1988) (1)
Chemical modification of the mitochondrial bc1 complex by N,N'-dicyclohexylcarbodiimide inhibits proton translocation. (1983) (1)
Mechanisms of the Effects of Hypothyroidism and Hyperthyroidism in Rats on Respiration Rate in Isolated Hepatocytes (1993) (1)
S12/6 Activity of uncoupling protein-2 in pancreatic beta cells (2008) (1)
Stimulation of 3-hydroxy-3-methylglutaryl coenzyme A synthase activity in rat liver mitochondria isolated from glucagon-treated rats (1987) (1)
Effects of sugars, fatty acids and amino acids on cytosolic and mitochondrial hydrogen peroxide release from liver cells (2022) (1)
Top Down Metabolic Control Analysis of Oxidative Phosphorylation at Different Rates in Potato Tuber Mitochondria (1993) (1)
Are the novel uncoupling proteins acutely regulated by fatty acids and nucleotides (2010) (1)
metabolism during exercise in humans Effect of endurance training on muscle TCA cycle (2015) (1)
Control analysis of gene expression (2002) (1)
can depolarize mitochondria in intact lymphocytes increasing plasma membrane potassium fluxes (1982) (1)
Tunicamycin Exposure Triggers Apopotosis by Superoxide Formation from Site IIIQo of Mitochondrial Complex III (2017) (1)
Fluorescence measurement of absolute mitochondrial membrane potential in adherent cultured cells (2010) (0)
Mitochondrial Complex II Generates Superoxide in the Forward and Reverse Directions (2011) (0)
Rat muscle mitochondria treated with dowex are GDP insensitive (2001) (0)
The isolation oflymphocyte mitochondria and their regulation of extramitochondrial free Ca 2 + concentration (2005) (0)
Mitochondria and the control of insulin secretion (2012) (0)
Abstract 215: Metabolic and mitochondrial consequences of p53 upregulation and their relation to cell fate outcomes (2016) (0)
The Control of Flux : 2 I Years On Control Analysis of energy metabolism in mitochondria (2009) (0)
Sites of Mitochondrial ROS Production during Long-Chain Fatty Acid Oxidation (2011) (0)
mitochondrial volume in skeletal muscles of old rats Greater capillary-fiber interface per fiber (2015) (0)
Mitochondrial Membrane Potential Heterogeneity in Cancer Cells is Independent of the Cell Cycle and Influences Response to Hyperpolarizing Agents (2019) (0)
Degradation of an intramitochondrial protein by the cytosolic proteasome (2010) (0)
Relationship between uncoupling proteins and mitochondrial proton leak in multiple tissues of arctic ground squirrels (2001) (0)
Control Analysis of Cellular Energy Metabolism in Intact, Adherent Cell Cultures (2018) (0)
S3.10 A role for uncoupling protein 1 in the formation of the mitochondrial permeability transition pore (2008) (0)
Microsoft Word-Goehring-ref (2012) (0)
Mechansims of energy conservation in hypoxic cold-submerged frogs. (2000) (0)
13L2Mitochondrial superoxide production under native conditions (2012) (0)
337 – Quantitative Estimation of ATP Production by Oxidative and Substrate-Level Phosphorylation Pathways Using Extracellular Flux Measurements (2015) (0)
Inhibition of Mitochondria1 Pyruvate Transport by Phenylpyruvate and α-Oxo-4-methylpentanoate (1974) (0)
THE H+/O STOICHIOMETRY OF RESPIRATION-LINKED H+ TRANSPORT IN LIVER MITOCHONDRIA (1981) (0)
S3.21 Contribution of mitochondrial carrier proteins to basal proton conductance (2008) (0)
Superoxide formation at the Q‐binding site of mitochondrial complex I does not arise from a semiquinone that has direct access to the bulk membrane QH2/Q pool (2010) (0)
Native Rates of Mitochondrial Superoxide Production: A Novel Method Utilizing Endogenous Reporters (2012) (0)
Abstract 3797: Wildtype p53 upregulation induces contrasting bioenergetic and metabolic responses in malignant and non-malignant mammary epithelial cells (2011) (0)
Nucleotide binding to purified, soluble uncoupling protein-2 (2001) (0)
A Refined Analysis of ROS Production from Mitochondrial sn-Glycerol-3-Phosphate Dehydrogenase (mGPDH) (2011) (0)
Dependence of Brown Adi pose Tissue Function on CD 36-Mediated Coenzyme Q Uptake Graphical (2015) (0)
Mitochondrial proton conductance in cold adapted king penguins: Keeping warm is a serious business. And there is more to it than fast swimming and a warm coat (2005) (0)
Functional Characterization of S1QELs (2016) (0)
Artefactual uncoupling following UCP3 expression in yeast mitochondria (2001) (0)
enzymes and lipid peroxidation in developing mice Modulations by dietary restriction on antioxidant (2015) (0)
Thermodynamic andsteady-state-kin etic investigation oftheeffect ofNN'- dicyclohexylcarbodi-imide onH+translocation bythemitochondrial cytochrome beccomplex (1985) (0)
Respiratory control in the mitochondrial bc1 complex (1985) (0)
RATE OF CALCIUM TRANSPORT BY RAT LIVER MITOCHONDRIA (1981) (0)
Development of a Kit to Measure Absolute Millivolts of Mitochondrial and Plasma Membrane Potentials in Cell Cultures (2018) (0)
Site IQ in mitochondrial complex I generates S1QEL-sensitive superoxide/hydrogen peroxide in both the reverse and forward reactions. (2022) (0)
Living at a snail's pace: the cellular basis of metabolic depression (2000) (0)
Supplementary material for 'A reduction in ATP demand and mitochondrial activity with neural differentiation of human embryonic stem cells' (2011) (0)
Extracting meaning from microarray data. (2003) (0)
Characterization and suppression of mitochondrial production of superoxide and hydrogen peroxide under near-physiological conditions (2014) (0)
Abstract 5160: Global metabolomic profiles distinguish malignant from non-malignant human mammary epithelial cell responses to endogenous p53 upregulation by MDM2 antagonism (2012) (0)
255 - Novel Insights into Mitochondrial Superoxide/H2O2 Production Rates in Vivo (2014) (0)
Experimental Discrimination between Proton Leak across the Mitochondrial Membrane and Slip in the Proton Pumps of the Electron Transport Chain (1993) (0)
Time Lapse Measurement of Mitochondrial Membrane Potential in Absolute Millivolts in Single Intact Cells (2012) (0)
CALCIUM EFFLUX FROM ISOLATED LIVER MITOCHONDRIA FOLLOWING OXIDATION OF ENDOGENOUS NUCLEOTIDES (1981) (0)
Control and kinetic which parts of the analysis of ischemia-damaged heart mitochondria: oxidative phosphorylation system are affected by ischemia? (2003) (0)
Control of energy metabolism (2000) (0)
S12.9 Dynamic regulation of UCP2 concentration in INS-1E pancreatic beta-cells (2008) (0)
Bioenergetics 2: by D. Nicholls and S. Ferguson Academic Press, 1982. £15.95 (ix + 248 pages) ISBN 0 12 518124 8 (1993) (0)
Cover Picture: A Prototypical Small-Molecule Modulator Uncouples Mitochondria in Response to Endogenous Hydrogen Peroxide Production (ChemBioChem 8/2013) (2013) (0)
An unexpected lack of difference in superoxide/H2O2 production rates in isolated heart and skeletal muscle mitochondria from a mouse model of Barth Syndrome (2020) (0)
The function of UCP1 homologues (2001) (0)
Higher Rates Than Complex I Superoxide / Hydrogen Peroxide at Much in Mitochondria Can Produce The 2-Oxoacid Dehydrogenase Complexes Bioenergetics : (2014) (0)
Successful Exogenous Expression of ATP8, a Mitochondrial Encoded Protein, From the Nucleus In Vivo (2021) (0)

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What Schools Are Affiliated With Martin D. Brand?

Martin D. Brand is affiliated with the following schools:

University of California, Berkeley
University of Manchester Institute of Science and Technology
University of Bristol
University of Wollongong
Stanford University
Johns Hopkins University
University of Cambridge

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