Martin Egli

Martin Egli's AcademicInfluence.com Rankings

Martin Egli

Chemistry

#3947

World Rank

#4998

Historical Rank

Organic Chemistry

#630

World Rank

#722

Historical Rank

chemistry Degrees

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Chemistry

Martin Egli's Degrees

PhD Chemistry University of Zurich
Masters Chemistry University of Zurich
Bachelors Chemistry University of Zurich

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Martin Egli's Published Works

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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Lone pair-aromatic interactions: to stabilize or not to stabilize. (2007) (454)
Minor groove RNA triplex in the crystal structure of a ribosomal frameshifting viral pseudoknot (1999) (217)
Recent Structural Insights into Cytochrome P450 Function. (2016) (202)
Stereoelectronic effects of deoxyribose O4' on DNA conformation. (1995) (182)
Visualizing a circadian clock protein: crystal structure of KaiC and functional insights. (2004) (180)
RNA hydration: a detailed look. (1996) (178)
A "Hydrat-Ion" Spine in a B-DNA Minor Groove (1999) (165)
Atomic-resolution crystal structures of B-DNA reveal specific influences of divalent metal ions on conformation and packing. (1999) (161)
DNA-cation interactions: quo vadis? (2002) (152)
Elucidating the Ticking of an In Vitro Circadian Clockwork (2007) (151)
Crystal structure and improved antisense properties of 2'-O-(2-methoxyethyl)-RNA (1999) (150)
Identification of key phosphorylation sites in the circadian clock protein KaiC by crystallographic and mutagenetic analyses. (2004) (146)
The Dickerson-Drew B-DNA Dodecamer Revisited-At Atomic Resolution (1998) (144)
DNA Adduct Bypass Polymerization by Sulfolobus solfataricus DNA Polymerase Dpo4 (2005) (141)
Unexpected origins of the enhanced pairing affinity of 2′-fluoro-modified RNA (2010) (140)
Unique gene-silencing and structural properties of 2'-fluoro-modified siRNAs. (2011) (140)
Crystal Structure of a Conformation-selective Casein Kinase-1 Inhibitor* (2000) (139)
Detection of alkali metal ions in DNA crystals using state-of-the-art X-ray diffraction experiments. (2001) (128)
Inter-strand C-H...O hydrogen bonds stabilizing four-stranded intercalated molecules: stereoelectronic effects of O4' in cytosine-rich DNA. (1996) (123)
Efficient and High Fidelity Incorporation of dCTP Opposite 7,8-Dihydro-8-oxodeoxyguanosine by Sulfolobus solfataricus DNA Polymerase Dpo4* (2005) (116)
The cyanobacterial circadian system: from biophysics to bioevolution. (2011) (115)
X-ray crystallographic analysis of the hydration of A- and B-form DNA at atomic resolution. (1998) (114)
The structural diversity of artificial genetic polymers (2015) (113)
Water-nucleobase "stacking": H-pi and lone pair-pi interactions in the atomic resolution crystal structure of an RNA pseudoknot. (2003) (109)
Analysis of KaiA–KaiC protein interactions in the cyano‐bacterial circadian clock using hybrid structural methods (2006) (106)
Metal ions and flexibility in a viral RNA pseudoknot at atomic resolution (2002) (104)
Crystal structures of the catalytic domain of human protein kinase associated with apoptosis and tumor suppression (2001) (98)
The low-temperature crystal structure of the pure-spermine form of Z-DNA reveals binding of a spermine molecule in the minor groove. (1993) (92)
Crystal structures of B-DNA with incorporated 2'-deoxy-2'-fluoro-arabino-furanosyl thymines: implications of conformational preorganization for duplex stability. (1998) (92)
Structure and Reactivity of Five‐ and Six‐Ring N, N‐, N, O‐, and O, O‐acetals: A lesson in allylic 1, 3‐strain (A1, 3 strain) (1992) (91)
2′-OMe-phosphorodithioate-modified siRNAs show increased loading into the RISC complex and enhanced anti-tumour activity (2014) (89)
Internal derivatization of oligonucleotides with selenium for X-ray crystallography using MAD. (2002) (88)
Structural Insights into a Circadian Oscillator (2008) (87)
Stabilizing effects of the RNA 2'-substituent: crystal structure of an oligodeoxynucleotide duplex containing 2'-O-methylated adenosines. (1994) (86)
Probing the influence of stereoelectronic effects on the biophysical properties of oligonucleotides: comprehensive analysis of the RNA affinity, nuclease resistance, and crystal structure of ten 2'-O-ribonucleic acid modifications. (2005) (85)
Consequences of Replacing the DNA 3‘-Oxygen by an Amino Group: High-Resolution Crystal Structure of a Fully Modified N3‘ → P5‘ Phosphoramidate DNA Dodecamer Duplex† (1998) (84)
Evoking picomolar binding in RNA by a single phosphorodithioate linkage (2016) (81)
An aminopyridazine-based inhibitor of a pro-apoptotic protein kinase attenuates hypoxia-ischemia induced acute brain injury. (2003) (81)
Gene silencing activity of siRNAs with a ribo-difluorotoluyl nucleotide. (2006) (80)
Sulfolobus solfataricus DNA Polymerase Dpo4 Is Partially Inhibited by “Wobble” Pairing between O6-Methylguanine and Cytosine, but Accurate Bypass Is Preferred* (2007) (80)
Structure of nogalamycin bound to a DNA hexamer. (1990) (78)
Re-Engineering RNA Molecules into Therapeutic Agents. (2019) (78)
Crystal structure of homo-DNA and nature's choice of pentose over hexose in the genetic system. (2006) (78)
Structural Aspects of Nucleic Acid Analogs and Antisense Oligonucleotides (1996) (78)
Structural model of the circadian clock KaiB–KaiC complex and mechanism for modulation of KaiC phosphorylation (2008) (78)
Structural origins of the exonuclease resistance of a zwitterionic RNA. (1999) (76)
The structure of the yrdC gene product from Escherichia coli reveals a new fold and suggests a role in RNA binding (2000) (75)
Kinetics, Structure, and Mechanism of 8-Oxo-7,8-dihydro-2′-deoxyguanosine Bypass by Human DNA Polymerase η*♦ (2014) (74)
Hydrogen Bonding of 7,8-Dihydro-8-oxodeoxyguanosine with a Charged Residue in the Little Finger Domain Determines Miscoding Events in Sulfolobus solfataricus DNA Polymerase Dpo4*♦ (2007) (74)
Conformational influence of the ribose 2'-hydroxyl group: crystal structures of DNA-RNA chimeric duplexes (1993) (73)
Structure of the pure-spermine form of Z-DNA (magnesium free) at 1-A resolution. (1991) (73)
Structure and photoinduced electron transfer in exceptionally stable synthetic DNA hairpins with stilbenediether linkers (1999) (72)
Structural and Functional Elucidation of the Mechanism Promoting Error-prone Synthesis by Human DNA Polymerase κ Opposite the 7,8-Dihydro-8-oxo-2′-deoxyguanosine Adduct* (2009) (71)
Dephosphorylation of the core clock protein KaiC in the cyanobacterial KaiABC circadian oscillator proceeds via an ATP synthase mechanism. (2012) (71)
Crystal structures of an A-form duplex with single-adenosine bulges and a conformational basis for site-specific RNA self-cleavage. (1996) (70)
Selenium-assisted nucleic acid crystallography: use of phosphoroselenoates for MAD phasing of a DNA structure. (2002) (69)
2'-Fluoro RNA shows increased Watson-Crick H-bonding strength and stacking relative to RNA: evidence from NMR and thermodynamic data. (2012) (68)
An exocyclic methylene group acts as a bioisostere of the 2'-oxygen atom in LNA. (2010) (67)
DNA recognition and bending. (1997) (67)
Lipophilic Tartaric Acid Esters as Enantioselective Ionophores (1989) (66)
Differential Stabilities and Sequence-Dependent Base Pair Opening Dynamics of Watson–Crick Base Pairs with 5-Hydroxymethylcytosine, 5-Formylcytosine, or 5-Carboxylcytosine (2015) (64)
Crystal structure of tricyclo-DNA: an unusual compensatory change of two adjacent backbone torsion angles. (2008) (63)
Drug-induced DNA repair: X-ray structure of a DNA-ditercalinium complex. (1991) (63)
Versatility of Y-family Sulfolobus solfataricus DNA Polymerase Dpo4 in Translesion Synthesis Past Bulky N2-Alkylguanine Adducts* (2009) (61)
A Protein Kinase Associated with Apoptosis and Tumor Suppression (2001) (60)
DNA-nogalamycin interactions. (1991) (60)
Nucleic acid crystallography: current progress. (2004) (59)
Crystal structure of a luteoviral RNA pseudoknot and model for a minimal ribosomal frameshifting motif. (2005) (59)
Synthesis, improved antisense activity and structural rationale for the divergent RNA affinities of 3'-fluoro hexitol nucleic acid (FHNA and Ara-FHNA) modified oligonucleotides. (2011) (57)
Crystal structure of a B-form DNA duplex containing (L)-alpha-threofuranosyl (3'-->2') nucleosides: a four-carbon sugar is easily accommodated into the backbone of DNA. (2002) (56)
Insights from crystallographic studies into the structural and pairing properties of nucleic acid analogs and chemically modified DNA and RNA oligonucleotides. (2007) (56)
Crystal structure of an Okazaki fragment at 2-A resolution. (1992) (56)
Why does TNA cross-pair more strongly with RNA than with DNA? an answer from X-ray analysis. (2003) (56)
Atomic-resolution structure of the cellulose synthase regulator cyclic diguanylic acid. (1990) (55)
Conformational influence of the ribose 2'-hydroxyl group: crystal structures of DNA-RNA chimeric duplexes. (1993) (55)
Molecular Dynamics of Hemiprotonated Intercalated Four-Stranded i-DNA: Stable Trajectories on a Nanosecond Scale (1998) (54)
Covalent incorporation of selenium into oligonucleotides for X-ray crystal structure determination via MAD: proof of principle. Multiwavelength anomalous dispersion. (2002) (53)
Structure and nuclease resistance of 2',4'-constrained 2'-O-methoxyethyl (cMOE) and 2'-O-ethyl (cEt) modified DNAs. (2012) (53)
Molecular Basis of Selectivity of Nucleoside Triphosphate Incorporation Opposite O6-Benzylguanine by Sulfolobus solfataricus DNA Polymerase Dpo4 (2007) (51)
Human Cytochrome P450 21A2, the Major Steroid 21-Hydroxylase (2015) (51)
2'-Fluoroarabino- and arabinonucleic acid show different conformations, resulting in deviating RNA affinities and processing of their heteroduplexes with RNA by RNase H. (2006) (51)
Chirality Dependent Potency Enhancement and Structural Impact of Glycol Nucleic Acid Modification on siRNA. (2017) (49)
Structures of KaiC Circadian Clock Mutant Proteins: A New Phosphorylation Site at T426 and Mechanisms of Kinase, ATPase and Phosphatase (2009) (47)
Structural Basis for Proficient Incorporation of dTTP Opposite O6-Methylguanine by Human DNA Polymerase ι* (2010) (46)
Face-to-face and edge-to-face pi-pi interactions in a synthetic DNA hairpin with a stilbenediether linker. (2003) (46)
CryoEM and molecular dynamics of the circadian KaiB-KaiC complex indicates that KaiB monomers interact with KaiC and block ATP binding clefts. (2013) (46)
Direct observation of a cytosine analogue that forms five hydrogen bonds to guanosine: guanidino G-clamp. (2002) (45)
Correlating structure and stability of DNA duplexes with incorporated 2'-O-modified RNA analogues. (1998) (45)
Crystal structure, stability and in vitro RNAi activity of oligoribonucleotides containing the ribo-difluorotoluyl nucleotide: insights into substrate requirements by the human RISC Ago2 enzyme (2007) (43)
Structural and Kinetic Basis of Steroid 17α,20-Lyase Activity in Teleost Fish Cytochrome P450 17A1 and Its Absence in Cytochrome P450 17A2* (2014) (43)
Metabolic compensation and circadian resilience in prokaryotic cyanobacteria. (2014) (43)
Crystal structures of thrombin in complex with chemically modified thrombin DNA aptamers reveal the origins of enhanced affinity (2018) (43)
Amides are excellent mimics of phosphate internucleoside linkages and are well tolerated in short interfering RNAs (2014) (42)
2'-O-[2-(guanidinium)ethyl]-modified oligonucleotides: stabilizing effect on duplex and triplex structures. (2004) (41)
Structural and Kinetic Analysis of Nucleoside Triphosphate Incorporation Opposite an Abasic Site by Human Translesion DNA Polymerase η* (2015) (40)
Structural basis of cleavage by RNase H of hybrids of arabinonucleic acids and RNA. (2000) (39)
Combined SAXS/EM Based Models of the S. elongatus Post-Translational Circadian Oscillator and its Interactions with the Output His-Kinase SasA (2011) (38)
Crystallographic Studies of Chemically Modified Nucleic Acids: A Backward Glance (2010) (38)
Redesigning nucleic acids (1998) (38)
Comparative studies of high resolution Z-DNA crystal structures. Part 1: Common hydration patterns of alternating dC-dG. (1994) (37)
4'-C-Methoxy-2'-deoxy-2'-fluoro Modified Ribonucleotides Improve Metabolic Stability and Elicit Efficient RNAi-Mediated Gene Silencing. (2017) (37)
A Comprehensive Strategy to Discover Inhibitors of the Translesion Synthesis DNA Polymerase κ (2012) (37)
X-ray crystal structure of a locked nucleic acid (LNA) duplex composed of a palindromic 10-mer DNA strand containing one LNA thymine monomer (2001) (37)
Functional implications from crystal structures of the conserved Bacillus subtilis protein Maf with and without dUTP. (2000) (36)
Intramolecular Regulation of Phosphorylation Status of the Circadian Clock Protein KaiC (2009) (35)
Crystal Structure of a Dimethylene Sulfone-Linked Ribodinucleotide Analog (1995) (35)
Calcium is a cofactor of polymerization but inhibits pyrophosphorolysis by the Sulfolobus solfataricus DNA polymerase Dpo4. (2006) (35)
Mechanism of Ribonucleotide Incorporation by Human DNA Polymerase η* (2016) (34)
Loop-loop interactions regulate KaiA-stimulated KaiC phosphorylation in the cyanobacterial KaiABC circadian clock. (2013) (33)
Syntheses of 4′-thioribonucleosides and thermodynamic stability and crystal structure of RNA oligomers with incorporated 4′-thiocytosine (2005) (32)
The steric hypothesis for DNA replication and fluorine hydrogen bonding revisited in light of structural data. (2012) (32)
Structural Basis of Duplex Thermodynamic Stability and Enhanced Nuclease Resistance of 5'-C-Methyl Pyrimidine-Modified Oligonucleotides. (2016) (32)
Crystal structure of a parallel-stranded duplex of a deoxycytidylyl-(3'-5')-deoxycytidine analog containing intranucleosidyl C(3')-C(5') ethylene bridges (1993) (31)
The crystal structure of r(CCCCGGGG) in two distinct lattices. (1995) (31)
Effects of N2,N2-dimethylguanosine on RNA structure and stability: crystal structure of an RNA duplex with tandem m2 2G:A pairs. (2008) (31)
Synthesis and Structure of 1-Deoxy-1-phenyl-beta-D-ribofuranose and Its Incorporation into Oligonucleotides. (1996) (31)
3,7-Dioxaazelaamides as Ionophores for Lithium Ion Selective Liquid Membrane Electrodes (1986) (31)
Synthesis and antisense properties of fluoro cyclohexenyl nucleic acid (F-CeNA), a nuclease stable mimic of 2'-fluoro RNA. (2012) (30)
A circadian clock nanomachine that runs without transcription or translation (2013) (30)
5-Methyltetrahydrofolate Is Bound in Intersubunit Areas of Rat Liver Folate-binding Protein Glycine N-Methyltransferase* (2006) (29)
2'-O-[2-(methylthio)ethyl]-modified oligonucleotide: an analogue of 2'-O-[2-(methoxy)-ethyl]-modified oligonucleotide with improved protein binding properties and high binding affinity to target RNA. (2002) (29)
Protein-Protein Interactions in the Cyanobacterial Circadian Clock: Structure of KaiA Dimer in Complex with C-Terminal KaiC Peptides at 2.8 Å Resolution. (2015) (28)
Structure-function relationships in miscoding by Sulfolobus solfataricus DNA polymerase Dpo4: guanine N2,N2-dimethyl substitution produces inactive and miscoding polymerase complexes. (2009) (28)
Bypass of Aflatoxin B1 Adducts by the Sulfolobus solfataricus DNA Polymerase IV (2011) (28)
Structural and Functional Analysis of Sulfolobus solfataricus Y-Family DNA Polymerase Dpo4-Catalyzed Bypass of the Malondialdehyde−Deoxyguanosine Adduct†,‡ (2009) (28)
Replication of N2,3-ethenoguanine by DNA polymerases. (2012) (28)
The Role of Backbone Oxygen Atoms in the Organization of Nucleic Acid Tertiary Structure: Zippers, Networks, Clamps, and C‐H…︁O Hydrogen Bonds (1997) (27)
Human DNA polymerase η accommodates RNA for strand extension (2017) (27)
Facile Synthesis, Geometry, and 2'-Substituent-Dependent in Vivo Activity of 5'-(E)- and 5'-(Z)-Vinylphosphonate-Modified siRNA Conjugates. (2018) (27)
Human DNA polymerase η has reverse transcriptase activity in cellular environments (2019) (27)
Roles of Residues Arg-61 and Gln-38 of Human DNA Polymerase η in Bypass of Deoxyguanosine and 7,8-Dihydro-8-oxo-2′-deoxyguanosine* (2015) (27)
RNA-Binding affinities and crystal structure of oligonucleotides containing five-atom amide-based backbone structures. (2006) (27)
Structural rationalization of a large difference in RNA affinity despite a small difference in chemistry between two 2'-O-modified nucleic acid analogues. (2004) (27)
Basis of Miscoding of the DNA Adduct N2,3-Ethenoguanine by Human Y-family DNA Polymerases* (2012) (27)
Pairing geometry of the hydrophobic thymine analogue 2,4-difluorotoluene in duplex DNA as analyzed by X-ray crystallography. (2009) (26)
Structure and Activity of Y-class DNA Polymerase DPO4 from Sulfolobus solfataricus with Templates Containing the Hydrophobic Thymine Analog 2,4-Difluorotoluene* (2007) (26)
2'-O-[2-[2-(N,N-dimethylamino)ethoxy]ethyl] modified oligonucleotides: symbiosis of charge interaction factors and stereoelectronic effects. (2003) (26)
Backbone-base inclination as a fundamental determinant of nucleic acid self- and cross-pairing (2007) (25)
Amide linkages mimic phosphates in RNA interactions with proteins and are well tolerated in the guide strand of short interfering RNAs (2017) (25)
Selenium modification of nucleic acids: preparation of oligonucleotides with incorporated 2′-SeMe-uridine for crystallographic phasing of nucleic acid structures (2007) (25)
Insights into RNA/DNA hybrid recognition and processing by RNase H from the crystal structure of a non-specific enzyme-dsDNA complex (2008) (25)
Stabilizing contributions of sulfur-modified nucleotides: crystal structure of a DNA duplex with 2′-O-[2-(methoxy)ethyl]-2-thiothymidines (2005) (25)
Structural Insights into Conformation Differences between DNA/TNA and RNA/TNA Chimeric Duplexes (2016) (25)
Functional analysis of human cytochrome P450 21A2 variants involved in congenital adrenal hyperplasia (2017) (25)
The many twists and turns of DNA: template, telomere, tool, and target. (2010) (25)
The long and winding road to the structure of homo-DNA. (2007) (24)
Structure of 11-deoxydaunomycin bound to DNA containing a phosphorothioate. (1990) (24)
Synthetic oligonucleotides as RNA mimetics: 2′-modified RNAs and N3′→P5′ phosphoramidates (2000) (24)
The Crystal Structure of r(CCCCGGGG) in Two Distinct Lattices (1996) (24)
Selenium modification of nucleic acids: preparation of phosphoroselenoate derivatives for crystallographic phasing of nucleic acid structures (2007) (23)
Structural basis for the synergy of 4′- and 2′-modifications on siRNA nuclease resistance, thermal stability and RNAi activity (2018) (23)
STUDIES OF A CHEMICALLY MODIFIED OLIGODEOXYNUCLEOTIDE CONTAINING A 5-ATOM AMIDE BACKBONE WHICH EXHIBITS IMPROVED BINDING TO RNA (2001) (23)
Conformational preorganization, hydration, and nucleic acid duplex stability. (1998) (23)
Large scale chemical synthesis, purification and crystallization of RNA-DNA chimeras. (1992) (22)
The solution conformation of a carbocyclic analog of the Dickerson-Drew dodecamer: comparison with its own X-ray structure and that of the NMR structure of the native counterpart. (1998) (22)
Crystal structure, stability and Ago2 affinity of phosphorodithioate-modified RNAs (2014) (22)
Insertion of dNTPs opposite the 1,N2-propanodeoxyguanosine adduct by Sulfolobus solfataricus P2 DNA polymerase IV. (2008) (22)
Chiral Poly(9,9′‐spirobifluorene) Crown Ethers (1985) (21)
Nature of KaiB-KaiC binding in the cyanobacterial circadian oscillator (2013) (21)
On the Macrolactonization of β‐Hydroxy Acids. Crystal structures of the pentolide and the hexolide from (R)‐3‐hydroxybutanoic acid. Molecular modeling studies of the tetrolide (1989) (21)
Synthesis, Duplex Stabilization and Structural Properties of a Fluorinated Carbocyclic LNA Analogue (2013) (19)
Intricate Protein-Protein Interactions in the Cyanobacterial Circadian Clock* (2014) (19)
X-ray crystallographic observation of "in-line" and "adjacent" conformations in a bulged self-cleaving RNA/DNA hybrid. (2001) (19)
A conformational transition in the structure of a 2'-thiomethyl-modified DNA visualized at high resolution. (2009) (19)
Research Resource: Correlating Human Cytochrome P450 21A2 Crystal Structure and Phenotypes of Mutations in Congenital Adrenal Hyperplasia. (2015) (19)
Molecular Basis of Selectivity of Nucleoside Triphosphate Incorporation Opposite O-Benzylguanine by Sulfolobus solfataricus DNA Polymerase Dpo4 STEADY-STATE AND PRE-STEADY-STATE KINETICS AND X-RAY CRYSTALLOGRAPHY OF CORRECT AND INCORRECT PAIRING*□ (2007) (19)
A Single Amide Linkage in the Passenger Strand Suppresses Its Activity and Enhances Guide Strand Targeting of siRNAs. (2018) (18)
Structural Basis for Recognition of Guanosine by a Synthetic Tricyclic Cytosine Analogue: Guanidinium G-Clamp (2003) (18)
Leukotriene biosynthesis inhibitor MK886 impedes DNA polymerase activity. (2013) (18)
Recognition of DNA adducts by edited and unedited forms of DNA glycosylase NEIL1. (2019) (18)
Structure, stability and function of 5-chlorouracil modified A:U and G:U base pairs (2012) (18)
Congener derivatives and conjugates of histamine: synthesis and tissue and receptor selectivity of the derivatives. (1987) (18)
Determining Functional Aptamer‐Protein Interaction by Biolayer Interferometry (2016) (18)
Lone Pair—Aromatic Interactions: To Stabilize or Not to Stabilize (2007) (17)
Chirale Poly(9,9′‐spirobifluoren)‐kronenether (1985) (17)
Recognition of O6-benzyl-2′-deoxyguanosine by a perimidinone-derived synthetic nucleoside: a DNA interstrand stacking interaction (2013) (16)
The conformationally constrained N-methanocarba-dT analogue adopts an unexpected C4'-exo sugar pucker in the structure of a DNA hairpin. (2012) (16)
Structural and Kinetic Basis of Steroid 17 , 20-Lyase Activity in Teleost Fish Cytochrome P 450 17 A 1 and Its Absence in Cytochrome P 450 17 A 2 * (2015) (16)
5'-C-Malonyl RNA: Small Interfering RNAs Modified with 5'-Monophosphate Bioisostere Demonstrate Gene Silencing Activity. (2016) (16)
Altering the Electrostatic Potential in the Major Groove: Thermodynamic and Structural Characterization of 7-Deaza-2′-deoxyadenosine:dT Base Pairing in DNA (2011) (16)
Chimeric siRNAs with chemically modified pentofuranose and hexopyranose nucleotides: altritol-nucleotide (ANA) containing GalNAc–siRNA conjugates: in vitro and in vivo RNAi activity and resistance to 5′-exonuclease (2020) (15)
Selective modulation of DNA polymerase activity by fixed-conformation nucleoside analogues. (2010) (15)
Inherent steroid 17α,20-lyase activity in defunct cytochrome P450 17A enzymes (2017) (15)
Label‐Free Electrophoretic Mobility Shift Assay (EMSA) for Measuring Dissociation Constants of Protein‐RNA Complexes (2018) (15)
Insights from crystal structures into the opposite effects on RNA affinity caused by the S- and R-6'-methyl backbone modifications of 3'-fluoro hexitol nucleic acid. (2012) (15)
Interplay of structure, hydration and thermal stability in formacetal modified oligonucleotides: RNA may tolerate nonionic modifications better than DNA. (2009) (15)
Diffraction Techniques in Structural Biology (2010) (14)
Enhanced Dispersion and Polarization Interactions Achieved through Dithiophosphate Group Incorporation Yield a Dramatic Binding Affinity Increase for an RNA Aptamer-Thrombin Complex. (2019) (14)
An arginine tetrad as mediator of input-dependent and input-independent ATPases in the clock protein KaiC. (2014) (14)
Metal-ion dependence of the active-site conformation of the translesion DNA polymerase Dpo4 from Sulfolobus solfataricus. (2010) (14)
Mechanisms of Insertion of dCTP and dTTP Opposite the DNA Lesion O6-Methyl-2′-deoxyguanosine by Human DNA Polymerase η* (2016) (13)
5'-Morpholino modification of the sense strand of an siRNA makes it a more effective passenger. (2019) (13)
Crystal structure of the redox-active cofactor dibromothymoquinone bound to circadian clock protein KaiA and structural basis for dibromothymoquinone's ability to prevent stimulation of KaiC phosphorylation by KaiA. (2012) (12)
Structural Aspects of the Enantioselectivity of Tartrates with α‐Amino‐alcohol Salts part. I. Crystal structures of eleven tartaric‐acid diesters (1989) (12)
Structural Basis for Error-Free Bypass of the 5-N-Methylformamidopyrimidine-dG Lesion by Human DNA Polymerase η and Sulfolobus solfataricus P2 Polymerase IV. (2015) (12)
Synthesis and Biophysical Characterization of RNAs Containing 2'-Fluorinated Northern Methanocarbacyclic Nucleotides. (2019) (12)
Impact of Chemical Adducts on Translesion Synthesis in Replicative and Bypass DNA Polymerases: From Structure to Function (2010) (12)
Synthesis, chirality-dependent conformational and biological properties of siRNAs containing 5′-(R)- and 5′-(S)-C-methyl-guanosine (2020) (11)
Structural and Kinetic Analysis of Miscoding Opposite the DNA Adduct 1,N6-Ethenodeoxyadenosine by Human Translesion DNA Polymerase η* (2016) (11)
Interactions between Functional Groups. Part III. The Structure of N,N-Dimethyl-8-nitro-1-naphthaleneamine in Seven Crystalline Environments (1986) (11)
Structural basis for the synergy of 4'- and 2'-modifications on siRNA nuclease resistance, thermal stability and RNAi activity. (2018) (10)
A bridging water anchors the tethered 5-(3-aminopropyl)-2'-deoxyuridine amine in the DNA major groove proximate to the N+2 C.G base pair: implications for formation of interstrand 5'-GNC-3' cross-links by nitrogen mustards. (2008) (10)
Chemistry and biology of artificial nucleic acids (2012) (10)
Effects of N 2 ,N 2 -dimethylguanosine on RNA structure and stability: Crystal structure of an RNA duplex with tandem m 22 G:A pairs (9)
The Dickerson-Drew B-DNA Dodecamer Revisited at Atomic Resolution J. Am. Chem. Soc. 1999, 121, 470−471]. A “Hydrat-Ion” Spine in a B-DNA Minor Groove [J. Am. Chem. Soc. 1999, 121, 3590−3595 (1999) (9)
Characterization of rare NEIL1 variants found in East Asian populations. (2019) (9)
Origins of the enhanced affinity of RNA-protein interactions triggered by RNA phosphorodithioate backbone modification. (2017) (9)
Crystal Structures of Oligodeoxyribonucleotides Containing 6'-alpha-Methyl and 6'-alpha-Hydroxy Carbocyclic Thymidines (1996) (9)
Beyond ribose and phosphate: Selected nucleic acid modifications for structure–function investigations and therapeutic applications (2021) (9)
Replication Bypass of the trans-4-Hydroxynonenal-Derived (6S,8R,11S)-1,N2-Deoxyguanosine DNA Adduct by the Sulfolobus solfataricus DNA Polymerase IV (2012) (8)
The residence time of the bound water in the hydrophobic minor groove of the carbocyclic-nucleoside analogs of Dickerson-Drew dodecamers. (1998) (8)
Lesion orientation of O4-alkylthymidine influences replication by human DNA polymerase η (2016) (8)
Structure and Function of the Ribosomal Frameshifting Pseudoknot RNA from Beet Western Yellow Virus (2003) (8)
Structural Patterns in Nucleic Acids (1994) (8)
X-ray crystal structure of a dimethylene sulfone-bridged ribonucleotide dimer in a single-stranded state (1995) (8)
Architecture and mechanism of the central gear in an ancient molecular timer (2017) (8)
Crystal Structures of Chiral Ionophores: Bis(9,9′-spirobifluorene)-26-crown-4 and -32-crown-6 (1986) (8)
Use of Antisense Vectors and Oligodeoxynucleotides in Neuro-Oncology (1998) (8)
Lattice- and Sequence-Dependent Binding of Mg2+in the Crystal Structure of a B-DNA Dodecamer (2004) (8)
siRNAs containing 2′-fluorinated Northern-methanocarbacyclic (2′-F-NMC) nucleotides: in vitro and in vivo RNAi activity and inability of mitochondrial polymerases to incorporate 2′-F-NMC NTPs (2021) (8)
Limits of RNA 2'-OH Mimicry by Fluorine: Crystal Structure of Bacillus halodurans RNase H Bound to a 2'-FRNA:DNA Hybrid. (2016) (8)
From bench to bedside: Improving the clinical safety of GalNAc–siRNA conjugates using seed-pairing destabilization (2022) (7)
In Vitro Selected Receptors Rationalized: The First 3D Structures of RNA Aptamer/Substrate Complexes (1997) (7)
Use of Chromophoric Ligands to Visually Screen Co‐Crystals of Putative Protein‐Nucleic Acid Complexes (2011) (7)
Crystallization and preliminary X-ray analysis of Escherichia coli RNase HI-dsRNA complexes. (2007) (7)
Structure-Function Relationships in Miscoding by Sulfolobus solfataricus DNA Polymerase Dpo4 (2009) (7)
Chirality matters: stereo-defined phosphorothioate linkages at the termini of small interfering RNAs improve pharmacology in vivo (2021) (7)
Visualizing a biological clockwork's cogs (2004) (7)
DNA Adduct Bypass Polymerization by Sulfolobus solfataricus Dpo4. Analysis and Crystal Structures of Multiple Base-Pair Substitution and Frameshift Products with the Adduct 1,N2-Ethenoguanine (2005) (7)
A nucleotide-analogue-induced gain of function corrects the error-prone nature of human DNA polymerase iota. (2012) (7)
Kinetic and Structural Impact of Metal Ions and Genetic Variations on Human DNA Polymerase ι* (2016) (6)
Structure and function of the translesion DNA polymerases and interactions with damaged DNA (2015) (6)
Towards the structure-based design of oligonucleotide therapeutics. (1998) (6)
Overcoming GNA/RNA base-pairing limitations using isonucleotides improves the pharmacodynamic activity of ESC+ GalNAc-siRNAs (2021) (6)
Cryo-neutron crystallographic data collection and preliminary refinement of left-handed Z-DNA d(CGCGCG). (2018) (6)
Structural Aspects of the Cyanobacterial KaiABC Circadian Clock (2009) (6)
Crystal structure of an RNA duplex containing phenyl-ribonucleotides, hydrophobic isosteres of the natural pyrimidines. (2000) (6)
Mechanism of Error‐Free Bypass of the Environmental Carcinogen N‐(2′‐Deoxyguanosin‐8‐yl)‐3‐aminobenzanthrone Adduct by Human DNA Polymerase η (2016) (6)
Incorporating a Thiophosphate Modification into a Common RNA Tetraloop Motif Causes an Unanticipated Stability Boost. (2020) (6)
A proposed complementary pairing mode between single-stranded nucleic acids and β-stranded peptides: A possible pathway for generating complex biological molecules (1995) (5)
PROTEIN-PROTEIN INTERACTIONS IN THE CYANOBACTERIAL KAIABC CIRCADIAN CLOCK (2005) (5)
Selenium-Assisted Nucleic Acid Crystallography: Use of DNA Phosphoroselenoates for MAD Phasing (2010) (5)
Covalent incorporation of selenium into oligonucleotides for X-ray crystal structure determination via MAD (2002) (5)
Water structure around a left-handed Z-DNA fragment analyzed by cryo neutron crystallography (2021) (5)
Structural and biophysical methods to analyze clock function and mechanism. (2015) (5)
Crystallization and preliminary X-ray diffraction analysis of double-helical RNA octamers. (1995) (5)
Functional analysis of human cytochrome P 450 21 A 2 variants involved in congenital adrenal hyperplasia (2017) (5)
Diffraction Techniques in Structural Biology (2010) (5)
Differential furanose selection in the active sites of archaeal DNA polymerases probed by fixed-conformation nucleotide analogues. (2012) (5)
Efficient and High Fidelity Incorporation of dCTP Opposite 7,8-Dihydro-8-oxodeoxyguanosine bySulfolobus solfataricus (2006) (5)
A hypothesis: Reciprocal information transfer between oligoribonucleotides and oligopeptides in prebiotic molecular evolution (1994) (5)
The Long and Winding Road to the Structure of Homo‐DNA (2007) (4)
Sugar Pucker and Nucleic Acid Structure (2018) (4)
A left-handed supramolecular assembly around a right-handed screw axis in the crystal structure of homo-DNA. (2007) (4)
The Enzyme‐Free Release of Nucleotides from Phosphoramidates Depends Strongly on the Amino Acid (2020) (4)
How the α-helix got its name (2022) (3)
Supramolecular Architecture through Self-Organization of Janus-Faced Homoazanucleosides. (2020) (3)
Chemistry, structure and function of approved oligonucleotide therapeutics (2023) (3)
Visualizing a Circadian Clock Protein (2004) (3)
Four-Stranded Intercalated Cytosine-Rich Molecules: Novel Insights into DNA Structure and Stability (1999) (3)
Silencing of oncogenic KRAS by mutant-selective small interfering RNA (2020) (3)
Backbone Flexibility Influences Nucleotide Incorporation by Human Translesion DNA Polymerase η opposite Intrastrand Cross-Linked DNA. (2015) (3)
Calorimetry of Nucleic Acids (2000) (3)
Ring-Opening of the γ-OH-PdG Adduct Promotes Error-Free Bypass by the Sulfolobus solfataricus DNA Polymerase Dpo4 (2013) (3)
In Situ Proteolysis for Crystallization of Membrane Bound Cytochrome P450 17A1 and 17A2 Proteins from Zebrafish (2016) (3)
Structural Aspects of the Enantioselectivity of Tartrates with α‐Amino‐alcohol Salts. Part II. Crystal structures of (1R, 2S)‐norephedrine hydrochloride and (1R, 2R)‐ norpseudoephedrine hydrochloride (1989) (3)
Chemistry and Biology of Aflatoxin-DNA Adducts (2012) (3)
"Deoxyribo nanonucleic acid"; antiparallel, parallel, and unparalleled. (2004) (3)
Mothers and Daughters: The Training of African Nurses by Missionary Nurses of the Swiss Mission in South Africa (1997) (3)
Small circular interfering RNAs (sciRNAs) as a potent therapeutic platform for gene-silencing (2021) (3)
Phosphorus SAD Phasing for Nucleic Acid Structures: Limitations and Potential (2016) (2)
Structure and nuclease resistance of 2 0 , 4 0-constrained 2 0-O-methoxyethyl ( cMOE ) and 2 0-O-ethyl ( cEt ) modified DNAs w (2012) (2)
Generating Crystallographic Models of DNA Dodecamers from Structures of RNase H:DNA Complexes. (2016) (2)
Structure and Reactivity of Five‐ and Six‐Ring N,N‐, N,O‐, and O,O‐ Acetals: A Lesson in Allylic 1,3‐Strain (A1,3 Strain). (1992) (2)
Biochemistry That Times the Day (2014) (2)
Erratum: Probing the influence of stereoelectronic effects on the biophysical properties of oligonucleotides: Comprehensive analysis of the RNA affinity, nuclease resistance, and crystal structure of ten 2′- O -ribonucleic acid modifications (Biochemistry (2005) 44: 25 (9045-9057) DOI: 10.1021/bi050 (2013) (2)
Tree Mortality may Drive Landscape Formation: Comparative Study from Ten Temperate Forests (2022) (2)
Molecular Dynamics Simulation of Homo-DNA: The Role of Crystal Packing in Duplex Conformation (2019) (2)
ReviewDNA-Cation Interactions : Quo Vadis ? (2002) (2)
Faculty Opinions recommendation of Quantitative and comprehensive decomposition of the ion atmosphere around nucleic acids. (2008) (2)
Role of a “Magic” Methyl: 2′-Deoxy-2′-α-F-2′-β-C-methyl Pyrimidine Nucleotides Modulate RNA Interference Activity through Synergy with 5′-Phosphate Mimics and Mitigation of Off-Target Effects (2022) (2)
Syntheses of 4 0 -thioribonucleosides and thermodynamic stability and crystal structure of RNA oligomers with incorporated 4 0 -thiocytosine (2005) (2)
EWALD: A macromolecular diffractometer for the second target station. (2022) (2)
RNAs Containing Carbocyclic Ribonucleotides. (2021) (2)
Enzymatic bypass and the structural basis of miscoding opposite the DNA adduct 1,N2-ethenodeoxyguanosine by human DNA translesion polymerase η (2021) (2)
2′‐O‐[2‐[2‐(N,N‐Dimethylamino)ethoxy]ethyl] Modified Oligonucleotides: Symbiosis of Charge Interaction Factors and Stereoelectronic Effects. (2003) (1)
First prediction of sequence-specific recognition of double-helix nucleic acids by proteins (2022) (1)
Hiding in plain sight: three chemically distinct α-helix types (2022) (1)
Diastereoselective Cyclization of a Glycylalanine Azomethine to an Imidazolidinone: Determination of the Product Configuration by X-Ray Analysis. (1989) (1)
(S)-cMOE-BNA decamer structure (2012) (1)
Conformation and Pairing Properties of an O6-Methyl-2'-deoxyguanosine-Directed Benzimidazole Nucleoside Analog in Duplex DNA. (2022) (1)
CRYSTAL STRUCTURE OF AN OKAZAKI FRAGMENT AT 2 ANGSTROMS RESOLUTION (1993) (1)
Sulfolobus solfataricus DNA Polymerase Dpo4 Is Partially Inhibitedby "Wobble"PairingbetweenO 6 -Methylguanine (2007) (1)
Ned Seeman and the prediction of amino acid-base pair motifs mediating sequence-specific recognition of nucleic acid duplexes by proteins. (2022) (1)
Acyclic (S)-glycol nucleic acid (S-GNA) modification of siRNAs improves the safety of RNAi therapeutics while maintaining potency (2023) (1)
Antimycotic Imidazolyl-alkenes: Synthesis and X-Ray Crystal Structure of Omoconazol. (1987) (1)
Structural Aspects of the Enantioselectivity of Tartaric Acid Esters with α-Amino Alcohol Salts. Part 1. Crystal Structures of Eleven Tartaric Acid Diesters (1989) (1)
High-resolution crystal structure of a fully modified N3'-> P5' phosphoramidate DNA dodecamer duplex (1997) (1)
Comparative analysis of inosine-substituted duplex DNA by circular dichroism and X-ray crystallography (2018) (1)
Mothers and Daughters (1997) (1)
Correction to Differential Stabilities and Sequence-Dependent Base Pair Opening Dynamics of Watson–Crick Base Pairs with 5-Hydroxymethylcytosine, 5-Formylcytosine, or 5-Carboxylcytosine (2015) (1)
Structure and Activity of Y-class DNA Polymerase DPO4 from Sulfolobus solfataricus with Templates Containing the (2007) (1)
Crystal Structure of Circadian clock protein KaiB from S.Elongatus (2013) (1)
BhRNase H - amide-RNA/DNA complex (2017) (0)
B-DNA with 7-deaza-dG modification (2008) (0)
X-ray structure of the A-decamer GCGTATACGC with a single 2'-o-butyl thymine in place of T6, Mg-form (2005) (0)
Zebra fish cytochrome P450 17A1 with Abiraterone (2014) (0)
R-Methyl Carbocyclic LNA (2010) (0)
Faculty Opinions recommendation of A simple glycol nucleic acid. (2005) (0)
Crystal structure of the phosphorylation-site mutant S431A of the KaiC circadian clock protein (2010) (0)
RNA octamer containing dT (2016) (0)
Faculty Opinions recommendation of Structural basis for differential insertion kinetics of dNMPs opposite a difluorotoluene nucleotide residue. (2012) (0)
Crystal Structure of 2'-Fluoro-RNA bearing a phosphorodithioate (2016) (0)
1.45 A STRUCTURE OF THE A-DECAMER GCGTATACGC WITH A SINGLE 2'-O-FLUOROETHYL THYMINE IN PLACE OF T6, MEDIUM NA-SALT (2001) (0)
DEATH ASSOCIATED PROTEIN KINASE CATALYTIC DOMAIN WITH BOUND INHIBITOR FRAGMENT (2004) (0)
Vinyl Carbocyclic LNA (2010) (0)
Crystal Structure Analysis of the A-DNA Decamer GCGT-2'OMeA-faT-ACGC, with Incorporated 2'-O-Methylated-Adenosine (2'OMeA) and 2'-Fluoroarabino-Thymidine (faT) (2006) (0)
SYNTHETIC DNA HAIRPIN WITH STILBENEDIETHER LINKER (2001) (0)
Structure of Prolinyl-5'-O-adenosine phosphoramidate (2021) (0)
Some functional insights from RNA crystal structures (1996) (0)
Complex structure of Sulfolobus solfataricus DPO4 and DNA duplex containing a hydrophobic thymine isostere 2,4-difluorotoluene nucleotide in the template strand (2007) (0)
The role of Arg332 in Dpo4‐catalyzed bypass of 7,8‐dihydro‐2′‐oxodeoxyguanosine (2007) (0)
The Role of Backbone Oxygen Atoms in the Organization of Nucleic Acid Tertiary Structure: Zippers, Networks, Clamps, and C‐H××. times.O Hydrogen Bonds (1997) (0)
Preface (2012) (0)
1.06 A STRUCTURE OF THE A-DECAMER GCGTATACGC WITH A SINGLE 2'-O-METHYL-3'-METHYLENEPHOSPHONATE (T23) THYMINE IN PLACE OF T6, HIGH CS-SALT (2001) (0)
Structure of beta-prolinyl 5'-O-adenosine phosphoramidate (2021) (0)
Faculty Opinions recommendation of Autonomously pairing cysteinyl-linked nucleotide analogues with a unique architecture. (2011) (0)
1.3 A STRUCTURE OF THE A-DECAMER GCGTATACGC WITH A SINGLE 2'-O-METHYL-[TRI(OXYETHYL)], MEDIUM K-SALT (2001) (0)
CRYSTAL STRUCTURE OF HUMAN DNA POLYMERASE ETA INSERTING dAMPNPP ACROSS A DNA TEMPLATE CONTAINING 1,N2-ETHENODEOXYGUANOSINE LESION (2016) (0)
Rational optimization of siRNA to ensure strand bias in the interaction with the RNA-induced silencing complex. (2023) (0)
Crystal structure of the A-DNA GCGTAT*CGC with a 2'-O-[2-[hydroxy(methyleneamino)oxy]ethyl] Thymidine (T*) (2005) (0)
BACILLUS HALODURANS RNASE H MUTANT D132N IN COMPLEX WITH 12-MER FRNA/DNA HYBRID (2016) (0)
Zebra fish cytochrome P450 17A2 with Progesterone (2014) (0)
Crystal structure of the A-DNA GCGTAT*CGC with a 2'-O-propargyl Thymidine (T*) (2005) (0)
Chapter 7 On Stacking (2010) (0)
2.4 A STRUCTURE OF A-DUPLEX WITH BULGED ADENOSINE, SPERMIDINE FORM (2001) (0)
Structure of Phenylalanyl-5'-O-adenosine phosphoramidate (2021) (0)
Structure and Activity of Bypass Synthesis by Human DNA Polymerase Kappa Opposite the 7,8-Dihydro-8-oxodeoxyguanosine Adduct (2009) (0)
An Aminopyridazine Inhibitor of Death Associated Protein Kinase Attenuates Hypoxia-Ischemia Induced Brain Damage (2010) (0)
Faculty Opinions recommendation of A fast selenium derivatization strategy for crystallization and phasing of RNA structures. (2009) (0)
Mutant Human DNA Polymerase Eta Q38A/R61A Inserting dCTP Opposite Template G (2015) (0)
Crystal Structure Analysis Of A 2-O-[2-(methoxy)ethyl]-2-thiothymidine Modified Oligodeoxynucleotide Duplex (2005) (0)
7-DEAZA-2'-DEOXYADENOSINE modification in B-FORM DNA (2011) (0)
Crystal Structure of Rat Glycine N-Methyltransferase Complexed With Folate (2006) (0)
Crystal structure of A-DNA decamer GCGTA(3ME)ACGC, with a modified 5-methyluridine (2003) (0)
Crystal structure of the A-DNA GCGTAT*CGC with a 2'-O-[2-(N,N-dimethylaminooxy)ethyl] Thymidine (T*) (2005) (0)
CRYSTAL STRUCTURE OF HUMAN DNA POLYMERASE ETA EXTENDING AN 1,N6-ETHENODEOXYADENOSINE : dA PAIR BY INSERTING dTMPNPP OPPOSITE TEMPLATE dA (2016) (0)
Crystal structure of the redox-active cofactor DBMIB bound to the full length circadian clock protein KaiA from Synechococcus elongatus (2012) (0)
Crystal Structure of inosine-substituted decamer duplex DNA (I4) (2017) (0)
Macrolactonization of β-Hydroxy Acids. Crystal Structures of the Pentolide and the Hexolide from (R)-3-Hydroxybutanoic Acid. Molecular Modeling Studies of the Tetrolide. (1990) (0)
DNA Polymerases , 3-Ethenoguanine by Human Y-family 2 N Basis of Miscoding of the DNA Adduct DNA and Chromosomes : (2012) (0)
1.5 A resolution structure of a synthetic DNA hairpin with a stilbenediether linker (2003) (0)
Ternary complex of Dpo4 bound to N2,N2-dimethyl-deoxyguanosine modified DNA with incoming dGTP (2009) (0)
(R)-cEt-BNA decamer structure (2012) (0)
Abstract 1406: Evoking potent RNAi response using novel 2′-OMe-phosphorodithioated modified siRNAs (2014) (0)
Structure of KaiA dimer in complex with C-terminal KaiC peptide at 2.8 A resolution (2015) (0)
A-DNA decamer GCGTA(UMS)ACGC with incorporated 2'-methylseleno-uridine (2002) (0)
Faculty Opinions recommendation of Rev1 employs a novel mechanism of DNA synthesis using a protein template. (2005) (0)
Crystal structure of the phosphorylation-site double mutant S431A/T432E of the KaiC circadian clock protein (2010) (0)
Biophysical Analysis of Nucleic Acids (2010) (0)
CALCIUM FORM OF THE B-DNA DODECAMER GGCGAATTCGCG (1999) (0)
Crystal structure of human polymerase eta extending an abasic site-dA pair by inserting dCTP opposite template G (2015) (0)
Faculty Opinions recommendation of Crystal structure of pseudouridine synthase RluA: indirect sequence readout through protein-induced RNA structure. (2006) (0)
Structure of perimidinone-derived synthetic nucleoside paired with guanine in DNA duplex (2013) (0)
Discovery of substrates and small molecule inhibitors for a death associated protein kinase (2001) (0)
Resource : Correlating Human Cytochrome P 450 21 A 2 Crystal Structure and Phenotypes of Mutations in Congenital Adrenal Hyperplasia (2015) (0)
Post-insertion complex of the Y-family DNA polymerase Dpo4 with M1dG containing template DNA (2009) (0)
Examining the S. elongatus KaiBC Complex by CryoEM and MDFF (2013) (0)
RNA octamer containing 2'-F, 4'-Cbeta-OMe U. (2018) (0)
Crystal Structure Analysis of the B-DNA Dodecamer CGCGAA-aU-TCGCG, with Incorporated Arabino-Uridine (aU) (2006) (0)
1.8A X-Ray structure of ternary complex of a catalytic domain of death-associated protein kinase with ATP analogue and Mn. (2002) (0)
1.05 A STRUCTURE OF THE A-DECAMER GCGTATACGC WITH A SINGLE 2'-O-METHYL-[TRI(OXYETHYL)] THYMINE IN PLACE OF T6, MEDIUM CS-SALT (2001) (0)
One Sugar Pucker Fits All: Pairing Versatility Despite Conformational Uniformity in TNA (2004) (0)
Alternatingly modified 2'Fluoro RNA octamer f/rA2U2-R32 (2011) (0)
Quadruplex Formation (2011) (0)
Synthesis and Biophysical Properties of Phosphorodiamidate Piperidino Oligomers. (2023) (0)
The Structures of Nucleic Acid Analogues and Antisense- Oligonucleotides (1996) (0)
RNA octamer containing (S)-5' methyl, 2'-F U. (2016) (0)
Ternary complex of human DNA polymerase eta inserting rCTP opposite template G (2016) (0)
Bh-RNaseH:2'-SMe-DNA complex (2015) (0)
Crystal structure of Y-family DNA polymerase Dpo4 bypassing a MeFapy-dG adduct (2015) (0)
Crystal structure of human DNA polymerase eta inserting dCMPNPP opposite a MeFapy-dG adducted DNA template (2015) (0)
Chiral Poly(9,9′-spirobifluorene) Crown Ethers. (1986) (0)
Structure and function of the translesion DNA polymerases and interactions with (2015) (0)
Interactions Between Functional Groups. Part 3. The Structure of N,N-Dimethyl-8-nitro-1-naphthaleneamine in Seven Crystalline Environments. (1986) (0)
CRYSTAL STRUCTURE OF THE COMPLEX OF DNA POLYMERASE I KLENOW FRAGMENT WITH DNA (1999) (0)
TETRAGONAL CRYSTAL FORM OF A CATALYTIC DOMAIN OF DEATH-ASSOCIATED PROTEIN KINASE (2002) (0)
Crystal structure of Ara-FHNA decamer DNA (2012) (0)
Biophysical Analysis of Nucleic Acids (2010) (0)
RNA oligonucleotide containing (R)-C5'-ME-2'F U (2016) (0)
Enantioselective Saponification of Diacetates of 2-Nitro-1,3-propanediols by Pig-Liver Esterase and Preparation of Enantiomerically Pure Derivatives of 2-Nitro-allylic Alcohols (Chiral Multiple-Coupling Reagents). (1988) (0)
Crystal structure of Y-family DNA polymerase Dpo4 extending from a MeFapy-dG:dC pair (2015) (0)
PS2 RNA: Sar and Biophysics (2018) (0)
PostInsertion complex of Human DNA Polymerase Eta bypassing an O6-Methyl-2'-deoxyguanosine : dC site (2016) (0)
RNA octamer containing glycol nucleic acid, SgnT (2017) (0)
Human DNA polymerase (cid:2) has reverse transcriptase activity in cellular environments (2019) (0)
Crystal structure of Dickerson Drew Dodecamer with 5-carboxycytosine (2015) (0)
Ned Seeman and the prediction of amino acid-basepair motifs mediating protein-nucleic acid recognition (2022) (0)
CRYSTALL STRUCTURE OF THE COMPLEX OF DNA POLYMERASE I KLENOW FRAGMENT WITH SHORT DNA FRAGMENT CARRYING 2'-0-AMINOPROPYL-RNA MODIFICATIONS 5'-D(TCG)-AP(AUC)-3' (1999) (0)
Amide linked RNA (2014) (0)
Decamer Fluoro Carbocyclic LNA (R-F-cLNA) crystal structure (2013) (0)
Sarcin-ricin loop with guanosine monothiophosphate residue. (2020) (0)
CRYSTAL STRUCTURE OF B. SUBTILIS MAF PROTEIN COMPLEXED WITH D-(UTP) (2000) (0)
Crystal structure of human polymerase eta inserting datp opposite an 8-oxog containing dna template (2014) (0)
Dodecamer structure of 5-formylcytosine containing DNA (2015) (0)
DUPLEX [5'-D(GCGTA+TACGC)]2 WITH INCORPORATED 2'-O-METHYL-[TRI(OXYETHYL)] RIBONUCLEOSIDE (1998) (0)
B-DNA DODECAMER CGCGAAT(TLC)CGCG WITH INCORPORATED [3.3.0]BICYCLO-ARABINO-THYMINE-5'-PHOSPHATE (2000) (0)
CRYSTAL STRUCTURE OF THE COMPLEX OF DNA POLYMERASE I KLENOW FRAGMENT WITH DNA TETRAMER CARRYING 2'-O-(3-AMINOPROPYL)-RNA MODIFICATION 5'-D(TT)-AP(U)-D(T)-3' (1999) (0)
Preface (2010) (0)
Dose-response activities of (A) candesartan cilexetil, (B) manoalide, and (C) MK-886 on adducted DNAs. (2012) (0)
Z-DNA joint X-ray/Neutron (2021) (0)
Structural Aspects of the Enantioselectivity of Tartrates with α-Amino Alcohol Salts. Part 2. Crystal Structures of (1R,2S)-Norephedrine Hydrochloride and (1R,2R)-Norpseudoephedrine Hydrochloride. (1989) (0)
, stability and Ago 2 a ffi nity of phosphorodithioate-modi fi ed RNAs † (2014) (0)
Crystal structures of mutant Dpo4 DNA polymerases with 8-oxoG containing DNA template-primer constructs (2007) (0)
CALCIUM FORM OF B-DNA UNDECAMER GCGAATTCGCG (1999) (0)
Non-productive complex of the Y-family DNA polymerase Dpo4 with dGTP skipping the M1dG adduct to pair with the next template cytosine (2009) (0)
A Chemical Approach to Introduce 2,6-Diaminopurine and 2-Aminoadenine Conjugates into Oligonucleotides without Need for Protecting Groups (2022) (0)
Faculty Opinions recommendation of Differential stability of 2'F-ANA*RNA and ANA*RNA hybrid duplexes: roles of structure, pseudohydrogen bonding, hydration, ion uptake and flexibility. (2010) (0)
Crystal Structures of Chiral Ionophores: Bis(9,9′-spirobifluorene)-26-crown-4 and -32-crown-6. (1986) (0)
Crystal Structure of Human DNA Polymerase Eta Inserting dATP Opposite O4-Methylhymidine (2016) (0)
RNA octamer containing 2'-F, 4'-Calpha-Me U. (2018) (0)
CRYSTAL STRUCTURE OF THE B-DNA DODECAMER 5'-D(CGCGAA(TAF)TCGCG), WHERE TAF IS 2'-DEOXY-2'-FLUORO-ARABINO-FURANOSYL THYMINE (1999) (0)
n of O 4-alkylthymidine in fl uences replication by human DNA polymerase h † (2016) (0)
Crystal structure of human polymerase eta inserting dAMPnPP opposite DNA template containing an abasic site (2015) (0)
TERNARY COMPLEX OF SULFOLOBUS SOLFATARICUS DPO4 DNA POLYMERASE, 7,8- DIHYDRO-8-OXODEOXYGUANINE MODIFIED DNA AND dCTP - MAGNESIUM FORM (2010) (0)
Quadruplex Formation (2010) (0)
Crystal Structure of inosine-substituted duplex DNA (2017) (0)
Structure and activity of human DNA polymerase kappa bypass of 8‐oxoG (2009) (0)
Crystal Structure of Full Length Circadian Clock Protein KaiC with Correct Geometry at Phosphorylation Sites (2009) (0)
Crystal Structure of Circadian Clock Protein KaiC with Phosphorylation Sites (2005) (0)
Faculty Opinions recommendation of Multicomponent assembly of proposed DNA precursors in water. (2012) (0)
CRYSTAL STRUCTURE OF AN RNA PSEUDOKNOT FROM BEET WESTERN YELLOW VIRUS INVOLVED IN RIBOSOMAL FRAMESHIFTING (1998) (0)
Back Cover: Structural Insights into Conformation Differences between DNA/TNA and RNA/TNA Chimeric Duplexes (ChemBioChem 18/2016) (2016) (0)
Bh-RNaseH:tcdA-DNA complex (2015) (0)
Binary complex of Dpo4 bound to N2,N2-dimethyl-deoxyguanosine modified DNA (2009) (0)
Structure of 3'-Fluoro Cyclohexenyl Nucleic Acid Heptamer (2012) (0)
Faculty Opinions recommendation of Reconstitution of circadian oscillation of cyanobacterial KaiC phosphorylation in vitro. (2005) (0)
Human Cytochrome P450 21A2, the Major Steroid 21-Hydroxylase STRUCTURE OF THE ENZYME (cid:2) PROGESTERONE SUBSTRATE COMPLEX AND RATE-LIMITING C–H BOND CLEAVAGE * (2020) (0)
First X-ray structure of RNA containing guanosine phosphorodithioate (2015) (0)
of selected papers in the field since 1997 in chronologi (2002) (0)
Selectivity of Nucleoside Triphosphate Incorporation Opposite 1,N2-Propanodeoxyguanosine (PdG) by the Sulfolobus solfataricus DNA Polymerase Dpo4 Polymerase (2008) (0)
Crystal structure of T. Elongatus BP-1 Clock Protein KaiC (2014) (0)
Restoration and use of the heritage for tourism. (1980) (0)
B-DODECAMER CGCGAA(TAF)TCGCG WITH INCORPORATED 2'-DEOXY-2'-FLUORO-ARABINO-FURANOSYL THYMINE (2000) (0)
DICKERSON-DREW DNA DODECAMER, NMR, MINIMIZED AVERAGE STRUCTURE (1998) (0)
Structure of RNA octamer (2020) (0)
Why Does TNACross-Pair More Strongly with RNA Than with DNA ? An Answer From X-ray Analysis (2003) (0)
Crystal Structure of Human DNA Polymerase Eta Inserting dAMPNPP Opposite O4-Ethylthymidine (2016) (0)
Sarcin-ricin loop with guanosine dithiophosphate residue. (2020) (0)
Surface runoff of phosphorus - an evaluation model (1998) (0)
Atomic Resolution Crystal Structure of a Viral RNA Pseudoknot (2002) (0)
Faculty Opinions recommendation of Large-scale phosphorylation analysis of mouse liver. (2009) (0)
Crystal structure of the A-DNA GCGTAT*CGC with a 2'-O-[2-(imidazolyl)ethyl] Thymidine (T*) (2005) (0)
Efficient and high fidelity incorporation of dCTP opposite 7,8-dihydro-8-oxodeoxyguanosine by Sulfolobus solfataricus DNA polymerase Dpo4. VOLUME 281 (2006) PAGES 2358-2372 (2008) (0)
Zebra fish cytochrome P450 17A2 with Abiraterone (2014) (0)
2'Fluoro modified RNA octamer fA2U2 (2011) (0)
pairs G : A 2 2 stability : Crystal structure of an RNA duplex with tandem m-dimethylguanosine on RNA structure and 2 , N 2 NEffects of Material Supplemental (0)
Mutant Human DNA Polymerase Eta Q38A/R61A Inserting dCTP Opposite an 8-Oxoguanine Lesion (2015) (0)
Alternatingly modified 2'Fluoro RNA octamer f/rC4G4 (2011) (0)
Remembering a giant of chemical crystallography (2021) (0)
Crystal structure of an Okazaki fragment at 2-Å resolution (2018) (0)
Crystal Structure of Circadian Clock Protein KaiC (2004) (0)
Hiding in plain sight: three chemically distinct α-helix types – ERRATUM (2022) (0)
5-MethyltetrahydrofolateIsBoundinIntersubunitAreasofRat LiverFolate-bindingProteinGlycineN-Methyltransferase * (2007) (0)
Crystal Structure of Circadian Clock Protein KaiC E318A Mutant (2012) (0)
RNA octamer containing 2'-OMe, 4'Calpha-OMe U. (2018) (0)
Sarcin-ricin loop with modified residue. (2020) (0)
Hairpin structure of a DNA dodecamer containing North-methanocarba-2'-deoxythymidine (2012) (0)
Crystal structure of RNA oligomer containing 4'-thioribose (2005) (0)
Crystal Structure Analysis of the A-DNA Decamer GCGT-2'OMeA-aU-ACGC, with Incorporated 2'-O-Methylated-Adenosine (2'OMeA) and Arabino-Uridine (aU) (2006) (0)
THE STRUCTURE OF THE YRDC GENE PRODUCT FROM E.COLI (2001) (0)
1.5A X-RAY STRUCTURE OF APO FORM OF A CATALYTIC DOMAIN OF DEATH-ASSOCIATED PROTEIN KINASE (2002) (0)
CRYSTAL STRUCTURE OF BACILLUS SUBTILIS MAF PROTEIN (2000) (0)
Functional basis of P 450 21 A 2 deficiencies 1 Functional Analysis of Human Cytochrome P 450 21 A 2 Variants Involved in Congenital Adrenal Hyperplasia (2017) (0)
1.3 A STRUCTURE OF THE A-DECAMER GCGTATACGC WITH A SINGLE 2'-O-METHYL-[TRI(OXYETHYL)] THYMINE IN PLACE OF T6, MEDIUM NA-SALT (2001) (0)
Crystal Structure of Human Cytochrome P450 21A2 Hydroxyprogesterone Complex (2015) (0)
Crystal Structure Analysis of a 2'-O-[2-(Methylthio)-ethyl]-Modified Oligodeoxynucleotide Duplex (2002) (0)
Ternary complex of human DNA polymerase eta inserting rATP opposite an 8-Oxodeoxyguanosine Lesion (2016) (0)
1.16A X-ray structure of the synthetic DNA fragment with the incorporated 2'-O-[(2-Guanidinium)ethyl]-5-methyluridine residues (2003) (0)
Biophysical Analysis of Nucleic Acids (2011) (0)
Crystal Structure of Rat Glycine N-Methyltransferase Apoprotein, Monoclinic Form (2006) (0)
Structure of R-GNA dodecamer (2017) (0)
Structure of 5-chlorouracil modified A:U base pair (2012) (0)
RNA octamer containing 2'-OMe, 4'- Cbeta-OMe U. (2018) (0)
Faculty Opinions recommendation of Hydrogen-bonding capability of a templating difluorotoluene nucleotide residue in an RB69 DNA polymerase ternary complex. (2011) (0)
Crystal structure of human dna polymerase eta in ternary complex with native dna and incoming nucleotide (dcp) (2014) (0)
Faculty Opinions recommendation of Evidence for Watson-Crick and not Hoogsteen or wobble base pairing in the selection of nucleotides for insertion opposite pyrimidines and a thymine dimer by yeast DNA pol eta. (2005) (0)
Cryo neutron crystallography demonstrates influence of RNA 2′-OH orientation on conformation, sugar pucker and water structure (2022) (0)
Transletion Polymerase Synthesis across C8-Guanine Adduct of the Environmental Carcinogen 3-Nitrobenzanthrone by Human DNA Polymerase Eta (2016) (0)
BINARY COMPLEX OF SULFOLOBUS SOLFATARICUS DPO4 DNA POLYMERASE AND 1, N2-ETHENOGUANINE MODIFIED DNA, MAGNESIUM FORM (2010) (0)
Erratum: A 'hydrat-ion' spine in a B-DNA minor groove (Journal of the American Chemical Society (1999) 121 (3590-3595)) (1999) (0)
Crystal Structure of Human DNA Polymerase Eta Inserting dTMPNPP Opposite O6-Methyl-2'-deoxyguanosine (2016) (0)
HIGHLIGHTS In Vitro Selected Receptors Rationalized : The First 3 D Structures of RNA Aptamer / Substrate Complexes * * (2003) (0)
RNA OCTAMER R(CCCP*GGGG) CONTAINING PHENYL RIBONUCLEOTIDE (2000) (0)
Crystal Structure of Human DNA Polymerase Eta Inserting dGMPNPP Opposite O4-Ethylthymidine (2016) (0)
Teranry complex of human DNA polymerase iota(26-445) inserting dCMPNPP opposite template G in the presence of Mg2+ (2016) (0)
Metabolically Stable Anomeric Linkages Containing GalNAc-siRNA Conjugates: An Interplay among ASGPR, Glycosidase, and RISC Pathways. (2023) (0)
Faculty Opinions recommendation of Coupling of a core post-translational pacemaker to a slave transcription/translation feedback loop in a circadian system. (2010) (0)
1.6 A STRUCTURE OF THE A-DECAMER GCGTATACGC WITH A SINGLE 2'-O-AMINOOXYETHYL THYMINE IN PLACE OF T6, BA-FORM (2001) (0)
Zebra Fish CYP-450 17A1 Mutant Abiraterone Complex (2017) (0)
Structure of glycinyl 5'-O-adenosine phosphoramidate (2020) (0)
Structure of O6-Benzyl-2'-deoxyguanosine opposite perimidinone-derived synthetic nucleoside in DNA duplex (2013) (0)
X-ray structure of 7-deaza-dG and Z3dU modified duplex CGCGAATXCZCG (2008) (0)
Crystal Structure of Human DNA Polymerase Eta Extending an O4-Ethylthymidine : dA Pair By Inserting dCTP Opposite dG (2016) (0)
Current Protocols in Nucleic Acid Chemistry: Preface (2010) (0)
Faculty Opinions recommendation of Structure of the parallel duplex of poly(A) RNA: evaluation of a 50 year-old prediction. (2013) (0)
Wild Type Crystal Structure of Full Length Circadian Clock Protein KaiB from Thermosynechococcus elongatus BP-1 (2008) (0)
Crystal structure of human polymerase eta extending an 8-oxog dna lesion: post insertion of 8-oxog-da pair (2014) (0)
3'-Fluoro Hexitol Nucleic Acid DNA Structure (2012) (0)
A. Sigel, H. Sigel, R. K. O. Sigel (Eds): The alkali metal ions: their role for life. Volume 16 of metal ions in life sciences (2016) (0)
Crystal Structure of Full Length Circadian Clock Protein KaiC with Phosphorylation Sites (2007) (0)
Base excision repair of the N-(2-deoxy-d-erythro-pentofuranosyl)-urea lesion by the hNEIL1 glycosylase. (2023) (0)
BINARY COMPLEX OF CASEIN KINASE-1 FROM S. POMBE WITH AN ATP COMPETITIVE INHIBITOR, IC261 (2001) (0)
3,7-Dioxaazelaamides as Ionophores for Lithium Ion Selective Liquid Membrane Electrodes. (1987) (0)
Ternary complex of Sulfolobus solfataricus Dpo4 DNA polymerase, O6- methylguanine modified DNA, and dATP. (2006) (0)
A-DNA DECAMER GCGTA(T23)TACGC WITH INCORPORATED 2'-METHOXY-3'-METHYLENEPHOSPHATE-THYMIDINE (2000) (0)
Crystal structure of R-6'-Me-3'-fluoro hexitol nucleic acid (2012) (0)
Y-family DNA polymerase Dpo4 bypassing N2-naphthyl-guanine adduct in anti orientation (2008) (0)
7 ON STACKING (2010) (0)
Crystal structure of the A-DNA GCGTAT*CGC with a 2'-O-[2-(fluoro)ethyl] Thymidine (T*) (2005) (0)
0.6 A STRUCTURE OF Z-DNA CGCGCG (2001) (0)
RNA octamer containing 2'-F-4'-OMe U. (2017) (0)
Analog of dickerson-drew DNA dodecamer with 6'-alpha-methyl carbocyclic thymidines, NMR, minimized average structure (1998) (0)
Thrombin-RNA aptamer complex (2016) (0)
Recent structural studies of KaiA and KaiB, two bacterial biological clock proteins, mark the beginning of a new phase in the analysis of circadian clock mechanisms. (2004) (0)
Faculty Opinions recommendation of Stabilization of G-quadruplex DNA and inhibition of telomerase activity by square-planar nickel(II) complexes. (2006) (0)
O6-2'-Deoxyguanosine-butylene-O6-2'-deoxyguanosine DNA Interstrand Cross-Links Are Replication-Blocking and Mutagenic DNA Lesions. (2016) (0)
Synthetic Oligonucleotides as RNA Mimetics: 2′-Modified RNAs and N3′P5′ Phosphoramidates (2001) (0)

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What Schools Are Affiliated With Martin Egli?

Martin Egli is affiliated with the following schools:

University of York
University of Oxford
ETH Zurich
Concordia University
Vanderbilt University
Massachusetts Institute of Technology
University of Basel
University of Vienna
University of Zurich