Martin Gellert
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Martin Gellert's Degrees
- Masters Computer Science Stanford University
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(Suggest an Edit or Addition)Martin Gellert's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage (2000) (2175)
- Mobile DNA III (2002) (1287)
- Helix formation by guanylic acid. (1962) (1248)
- DNA gyrase: an enzyme that introduces superhelical turns into DNA. (1976) (1042)
- The 3' to 5' exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks. (1998) (926)
- V(D)J recombination: RAG proteins, repair factors, and regulation. (2002) (746)
- Nalidixic acid resistance: a second genetic character involved in DNA gyrase activity. (1977) (731)
- Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps (1995) (702)
- Novobiocin and coumermycin inhibit DNA supercoiling catalyzed by DNA gyrase. (1976) (640)
- Nbs1 potentiates ATP-driven DNA unwinding and endonuclease cleavage by the Mre11/Rad50 complex. (1999) (574)
- DNA Transposition by the RAG1 and RAG2 Proteins A Possible Source of Oncogenic Translocations (1998) (536)
- V(D)J recombination: a functional definition of the joining signals. (1989) (443)
- The defect in murine severe combined immune deficiency: Joining of signal sequences but not coding segments in V(D)J recombination (1988) (433)
- V(D)J recombination: Broken DNA molecules with covalently sealed (hairpin) coding ends in scid mouse thymocytes (1992) (427)
- Regulation of the genes for E. coli DNA gyrase: Homeostatic control of DNA supercoiling (1983) (420)
- Extrachromosomal DNA substrates in pre-B cells undergo inversion or deletion at immunoglobulin V-(D)-J joining signals (1987) (315)
- Ku protein stimulates DNA end joining by mammalian DNA ligases: a direct role for Ku in repair of DNA double‐strand breaks (1998) (315)
- Initiation of V(D)J recombination in a cell-free system (1995) (297)
- Direct DNA binding by Brca1 (2001) (280)
- The RAG1 and RAG2 Proteins Establish the 12/23 Rule in V(D)J Recombination (1996) (277)
- Similarities Between Initiation of V(D)J Recombination and Retroviral Integration (1996) (275)
- Stimulation of V(D)J cleavage by high mobility group proteins (1997) (244)
- DNA gyrase: subunit structure and ATPase activity of the purified enzyme. (1978) (241)
- Assembly of a 12/23 paired signal complex: a critical control point in V(D)J recombination. (1998) (231)
- A Stable RAG1–RAG2–DNA Complex That Is Active in V(D)J Cleavage (1997) (206)
- A mechanistic basis for Mre11-directed DNA joining at microhomologies. (2000) (205)
- Mechanistic aspects of DNA topoisomerases. (1986) (200)
- Recent advances in understanding V(D)J recombination. (1997) (199)
- ACTINOMYCIN BINDING TO DNA: MECHANISM AND SPECIFICITY. (1965) (196)
- DNA gyrase action involves the introduction of transient double-strand breaks into DNA. (1980) (196)
- DNA repair: from molecular mechanism to human disease. (2006) (187)
- Crystal structure of the Xrcc4 DNA repair protein and implications for end joining (2000) (186)
- DNA binding of Xrcc4 protein is associated with V(D)J recombination but not with stimulation of DNA ligase IV activity (1999) (183)
- Formation of covalent circles of lambda DNA by E. coli extracts. (1967) (182)
- Cruciform structures in palindromic DNA are favored by DNA supercoiling. (1982) (181)
- Distinct DNA sequence and structure requirements for the two steps of V(D)J recombination signal cleavage. (1996) (174)
- Genetics and function of DNA ligase in Escherichia coli. (1973) (174)
- V(D)J recombination in mouse thymocytes: Double-strand breaks near T cell receptor δ rearrangement signals (1992) (169)
- Lymphoid V(D)J recombination: nucleotide insertion at signal joints as well as coding joints. (1988) (168)
- Characterization of broken DNA molecules associated with V(D)J recombination. (1993) (165)
- Novel strand exchanges in V(D)J recombination (1988) (164)
- Developmental stage specificity of the lymphoid V(D)J recombination activity. (1987) (158)
- Formation and resolution of double-strand break intermediates in V(D)J rearrangement. (1995) (157)
- Definition of a core region of RAG-2 that is functional in V(D)J recombination. (1994) (155)
- DNA gyrase: purification and catalytic properties of a fragment of gyrase B protein. (1979) (142)
- DNA sequence of the E. coli gyrB gene: application of a new sequencing strategy. (1987) (140)
- Crystal structure of the V(D)J recombinase RAG1–RAG2 (2015) (139)
- Mechanism of mismatch recognition revealed by human MutSβ bound to unpaired DNA loops (2011) (138)
- DNA gyrase and DNA supercoiling. (1979) (133)
- Cell-free V(D)J recombination (1997) (133)
- Enzymatic joining of DNA strands: a novel reaction of diphosphopyridine nucleotide. (1967) (130)
- The DNA dependence of the ATPase activity of DNA gyrase. (1984) (127)
- Expression and V(D)J recombination activity of mutated RAG-1 proteins. (1993) (125)
- The taming of a transposon: V(D)J recombination and the immune system (2004) (125)
- Site-specific interaction of DNA gyrase with DNA. (1981) (122)
- Cloning and simplified purification of Escherichia coli DNA gyrase A and B proteins. (1984) (114)
- Interactions of CcdB with DNA Gyrase (1999) (107)
- Ordered assembly of the V(D)J synaptic complex ensures accurate recombination (2002) (107)
- Molecular analysis of V(D)J recombination. (1992) (106)
- Rejoining of DNA by the RAG1 and RAG2 proteins. (1998) (106)
- Fusions of the Escherichia coli gyrA and gyrB control regions to the galactokinase gene are inducible by coumermycin treatment (1987) (103)
- Modulation of transcription by DNA supercoiling: a deletion analysis of the Escherichia coli gyrA and gyrB promoters. (1987) (101)
- Communication between segments of DNA during site-specific recombination (1987) (97)
- Characterization of bacteriophage lambda reverse as an Escherichia coli phage carrying a unique set of host-derived recombination functions. (1974) (96)
- The mechanism of antigen receptor gene assembly (1989) (94)
- The interaction of the F plasmid killer protein, CcdB, with DNA gyrase: induction of DNA cleavage and blocking of transcription. (1997) (91)
- Repair and Recombination: How to make ends meet (1995) (91)
- DNA topoisomerase V is a relative of eukaryotic topoisomerase I from a hyperthermophilic prokaryote (1993) (90)
- Differential sensitivity of gene expression in vitro to inhibitors of DNA gyrase. (1979) (90)
- Slow cruciform transitions in palindromic DNA. (1983) (84)
- Intermediates in V(D)J recombination: A stable RAG1/2 complex sequesters cleaved RSS ends (2001) (83)
- Involement of supertwisted DNA in integrative recombination of bacteriophage lambda. (1978) (80)
- Tetramerization and DNA ligase IV interaction of the DNA double-strand break repair protein XRCC4 are mutually exclusive. (2003) (80)
- Autoubiquitylation of the V(D)J recombinase protein RAG1 (2003) (75)
- Characterization of the ATP binding site on Escherichia coli DNA gyrase. Affinity labeling of Lys-103 and Lys-110 of the B subunit by pyridoxal 5'-diphospho-5'-adenosine. (1990) (74)
- Synergistic effect of himA and gyrB mutations: evidence that him functions control expression of ilv and xyl genes (1984) (71)
- DNA ligase mutants of Escherichia coli. (1970) (70)
- RAG-1 mutations that affect the target specificity of V(D)j recombination: a possible direct role of RAG-1 in site recognition. (1995) (69)
- Structure of the DNA gyrase-DNA complex as revealed by transient electric dichroism. (1987) (68)
- RAG1/2-Mediated Resolution of Transposition Intermediates Two Pathways and Possible Consequences (2000) (67)
- Expression and V(D)J recombination activity of mutated RAG-1 proteins. (1994) (66)
- V(D)J recombination activity in lymphoid cell lines is increased by agents that elevate cAMP. (1990) (61)
- Catenation and supercoiling in the products of bacteriophage λ integrative recombination in vitro (1980) (60)
- Studies on the Contractile Proteins of Muscle. I. The ATP-Myosin B Interaction1,2 (1959) (57)
- Enzymatic joining of DNA strands, II. An enzyme-adenylate intermediate in the dpn-dependent DNA ligase reaction. (1967) (56)
- A two-subunit type I DNA topoisomerase (reverse gyrase) from an extreme hyperthermophile. (1996) (52)
- Regulation of DNA supercoiling in Escherichia coli. (1983) (52)
- Energy coupling in Escherichia coli DNA gyrase: the relationship between nucleotide binding, strand passage, and DNA supercoiling. (1996) (52)
- Autoinhibition of DNA cleavage mediated by RAG1 and RAG2 is overcome by an epigenetic signal in V(D)J recombination (2010) (51)
- Purification and characterization of DNA topoisomerase V. An enzyme from the hyperthermophilic prokaryote Methanopyrus kandleri that resembles eukaryotic topoisomerase I. (1994) (50)
- Cracking the DNA Code for V(D)J Recombination. (2018) (49)
- Initial stages of V(D)J recombination: the organization of RAG1/2 and RSS DNA in the postcleavage complex. (2009) (49)
- V-D-J rearrangements at the T cell receptor σ locus in mouse thymocytes of the αβ lineage (1995) (48)
- Structure of an activated DNA-PK and its implications for NHEJ. (2020) (47)
- A Ku bridge over broken DNA. (2001) (46)
- Effect of HIV integrase inhibitors on the RAG1/2 recombinase (2001) (44)
- The molecular weight of rabbit myosin A by light scattering. (1963) (44)
- DNA topoisomerases. (1981) (44)
- Neutron and light-scattering studies of DNA gyrase and its complex with DNA. (1990) (42)
- V(D)J recombination gets a break. (1992) (40)
- Mutations in the DNA gyrB gene that are temperature sensitive for lambda site-specific recombination, Mu growth, and plasmid maintenance (1984) (39)
- Specificity in V(D)J recombination: new lessons from biochemistry and genetics. (1997) (35)
- Effects of DNA supercoiling on the topological properties of nucleosomes. (1987) (35)
- The biochemistry and biology of DNA gyrase. (1994) (34)
- Initiation of V(D)J recombinations in a cell-free system by RAG1 and RAG2 proteins. (1996) (34)
- DNA sequence and transcription of the region upstream of the E. coli gyrB gene. (1984) (34)
- Slow interaction of 5'-adenylyl-beta,gamma-imidodiphosphate with Escherichia coli DNA gyrase. Evidence for cooperativity in nucleotide binding. (1992) (34)
- V(D)J recombination in mouse thymocytes: double-strand breaks near T cell receptor delta rearrangement signals. (1992) (33)
- Spectral analysis of the intramolecular heterogeneity of λ DNA (1967) (32)
- Mutations in the B Subunit of Escherichia coli DNA Gyrase That Affect ATP-dependent Reactions (*) (1996) (32)
- A reverse gyrase with an unusual structure. A type I DNA topoisomerase from the hyperthermophile Methanopyrus kandleri is a two-subunit protein. (1994) (31)
- ORGANIZATION OF DNA IN BACTERIOPHAGE T4. (1964) (31)
- V(D)J Recombination (2002) (31)
- DNA gyrase: site-specific interactions and transient double-strand breakage of DNA. (1981) (30)
- The Association of Insulin. I. Preliminary Investigations (1952) (30)
- Joining of DNA strands by DNA ligase of E. coli. (1968) (26)
- Requirements for DNA hairpin formation by RAG1/2 (2007) (26)
- A new view of V(D)J recombination (1996) (26)
- The binding of p-chloromercuribenzoate by myosin. (1961) (25)
- ON THE ASSIGNMENT OF n → π/*TRANSITIONS IN POLYNUCLEOTIDES (1961) (24)
- V(D)J recombination: links to transposition and double-strand break repair. (1999) (24)
- Cancer: New guardians of the genome (2000) (24)
- DNA supercoiling by DNA gyrase (2008) (23)
- The Enthalpy Change in the Hydrolysis of Creatine Phosphate (1960) (20)
- 19 DNA Gyrase and Other Type II Topoisomerases (1981) (20)
- Cutting antiparallel DNA strands in a single active site (2019) (20)
- Reverse Gyrase from Methanopyrus kandleri (1997) (19)
- Role of RAG1 autoubiquitination in V(D)J recombination (2015) (17)
- Metabolic sensor AMPK directly phosphorylates RAG1 protein and regulates V(D)J recombination (2013) (17)
- Mechanism of illegitimate recombination: Common sites for recombination and cleavage mediated by E. coli DNA gyrase (2004) (16)
- High Resolution Analysis of the Chromatin Landscape of the IgE Switch Region in Human B Cells (2011) (15)
- Autophosphorylation transforms DNA-PK from protecting to processing DNA ends. (2021) (15)
- Studies on the Contractile Proteins of Muscle. II. Polymerization Reactions in the Myosin B System1,2 (1959) (13)
- ["In the beginning the horse is sad"--a historical abstract of Borna disease]. (1995) (12)
- Inverse transposition by the RAG1 and RAG2 proteins: role reversal of donor and target DNA (2002) (12)
- Assembly Pathway and Characterization of the RAG1/2-DNA Paired and Signal-end Complexes* (2015) (12)
- Rapid generation of novel models of RAG1 deficiency by CRISPR/Cas9-induced mutagenesis in murine zygotes (2016) (12)
- Erratum: Expression and V(D)J recombination activity of mutated RAG-1 proteins (Nucleic Acids Research (1993) 21 (5644-5650)) (1994) (11)
- DNA double-strand breaks and hairpins in V(D)J recombination. (1994) (11)
- How mouse RAG recombinase avoids DNA transposition (2019) (11)
- Studies of V(D)J recombination with extrachromosomal substrates. (1988) (10)
- [Electron microscopic study of striatodental calcification (Fahr) (author's transl]. (1975) (9)
- Inner workings of RAG recombinase and its specialization for adaptive immunity. (2021) (9)
- Mechanistic studies of dna gyrase (1986) (7)
- Steps along the pathway of V (D)J recombination. (1995) (6)
- Double-Strand Breaks Associated with V(D)J Recombination at the TCRδ Locus in Murine Thymocytes (1992) (6)
- Catenation and supercoiling in the products of bacteriophage lambda integrative recombination in vitro. (1980) (6)
- Genetics and Physiology of DNA Ligase Mutants of Escherichia coli (1973) (6)
- Abnormal V(D)J recombination in murine severe combined immune deficiency: absence of coding joints and formation of alternative products. Abnormal V(D)J recombination in murine severe combined immune deficiency: absence of coding joints and formation of alternative products. (1989) (5)
- An Activation-Induced Cytidine Deaminase-Independent Mechanism of Secondary VH Gene Rearrangement in Preimmune Human B Cells1 (2008) (4)
- V-D-J rearrangements at the T cell receptor delta locus in mouse thymocytes of the alpha beta lineage. (1995) (3)
- Integrative Recombination of Bacteriophage Lambda: Genetics and Biochemistry (1978) (3)
- DNA Supercoiling as a Regulator of Bacterial Gene Expression (1987) (2)
- Double-strand breaks associated with V(D)J recombination at the TCR delta locus in murine thymocytes. (1992) (2)
- National protein and nucleic acid databases. (1994) (2)
- Spectral analysis of the intramolecular heterogeneity of lambda-DNA. (1967) (1)
- The genome project: pro and con. (1990) (1)
- Minutes of the Human Gene Therapy Subcommittee meeting, November 21-22, 1991 (1994) (1)
- V(D)J recombination: mechanism and consequences (2006) (1)
- [26] Assay of DNA ligase by covalent joining of λ DNA molecules (1971) (1)
- Two distinct long-range synaptic complexes promote different aspects of end processing prior to repair of DNA breaks by non-homologous end joining. (2023) (1)
- Evidence for Separate Functions for Two Distinct Non-Homologous End Joining Long-Range Synaptic Complexes (2022) (1)
- Incorporating Minorities in Science (1994) (0)
- Hairpin Complex, RAG1/2-hairpin 12RSS/23RSS complex in 5mM Mn2+ for 2 min at 4'C (2018) (0)
- Book Review:Progress in Biophysics and Molecular Biology. Volume 13. J. A. V. Butler, H. E. Huxley, R. E. Zirkle (1964) (0)
- Cryo-EM structure of mouse RAG1/2 HFC complex containing partial HMGB1 linker(3.9 A) (2018) (0)
- ["...that subsequently homeopathy will become nowhere as common as in veterinary medicine"--the history of veterinary homeopathy in Germany]. (1995) (0)
- Cryo-EM structure of mouse RAG1/2 STC complex (2020) (0)
- CryoEM structure of inactivated-form FATKIN domain of DNA-PK (2021) (0)
- PRE-REACTION COMPLEX, RAG1(E962Q)/2-INTACT/INTACT 12/23RSS COMPLEX IN MN2+ (2018) (0)
- How limitless antibodies are generated by V(D)J recombination (2021) (0)
- Pre-Reaction Complex, RAG1(E962Q)/2-nicked/intact 12/23RSS complex in Mn2+ (2018) (0)
- Cryo-EM structure of mouse RAG1/2 PRC complex (DNA0) (2020) (0)
- Cryo-EM structure of mouse RAG1/2 PRC complex (DNA1) (2020) (0)
- D)J recombination: a functional efinition of the joining signals (2007) (0)
- Stretch and Twist of HEAT Repeats Leads to Activation of DNA-PK Kinase (2020) (0)
- CryoEM structure of activated-form FATKIN domain of DNA-PK (2021) (0)
- Hairpin Forming Complex, RAG1/2-Nicked 12RSS/23RSS complex in Ca2+ (2018) (0)
- STUDIES ON THE ENZYMATIC JOINING OF DNA STRANDS. (1970) (0)
- Cryo-EM structure of mouse RAG1/2 HFC complex (3.17 A) (2018) (0)
- RoleofDNA gyrase subunits insynthesis ofbacteriophage 4X174 viral DNA (1981) (0)
- V ( D ) J recombination activity in lymphoid cell lines is increased by agents that elevate cAMP ( site-specific recombiation / protein kinase / antigen receptor genes ) (0)
- Cryo-EM structure of mouse RAG1/2 STC complex (without NBD domain) (2020) (0)
- CRYSTAL STRUCTURE OF HUMAN XRCC4 (2000) (0)
- EVIDENCE FOR COOPERATIVITY IN NUCLEOTIDE BINDING* (2001) (0)
- DNA topoisomerases: an overview (1986) (0)
- Mutations intheDNA gyrBGeneThatAreTemperature Sensitive forLambdaSite-Specific Recombination, Mu Growth, andPlasmid Maintenance (1984) (0)
- CryoEM structure of inactivated-form DNA-PK (Complex IV) (2021) (0)
- Studies on the mechanism and regulation of DNA gyrase (1986) (0)
- CryoEM structure of inactivated-form DNA-PK (Complex V) (2021) (0)
- Pre-Reaction Complex, RAG1(E962Q)/2-intact/nicked 12/23RSS complex in Mn2+ (2018) (0)
- The repair of double-stranded breaks in DNA and the recombination of antibody gene V(D)J segments share a common pathway involving the Ku protein, which binds DNA ends, and its associated protein kinase. (1995) (0)
- Hairpin Forming Complex, RAG1/2-Nicked 12RSS/23RSS complex in 2mM Mn2+ for 10 min at 4'C (2018) (0)
- CryoEM structure of DNA-PK catalytic subunit complexed with DNA (Complex I) (2021) (0)
- Cutting antiparallel DNA strands in a single active site (2020) (0)
- Books Rreceived (2003) (0)
- The Lymphoid V(D)J Recombination Activity: Studies of Exogenous Plasmid Substrates in Whole Cells (1989) (0)
- Hairpin Forming Complex, RAG1/2-Nicked(with Dideoxy) 12RSS/23RSS complex in Mg2+ (2018) (0)
- Organization of RAG1/2 and RSS DNA in the Post-Cleavage Complex (2010) (0)
- A Ku Bridge over Broken DNA Minireview (2001) (0)
- Crystal structure of the core RAG1/2 recombinase (2015) (0)
- Double labelled T suppressor lymphocytes in the thymus of a patient with myasthenia gravis: morphological and immunological characteristics. (1982) (0)
- Cryo-EM structure of mouse WT RAG1/2 NFC complex (DNA0) (2020) (0)
- Structure and properties of hyperthermophilic DNA topoisomerases (1994) (0)
- Cryo-EM structure of mouse RAG1/2 12RSS-NFC/23RSS-PRC complex (DNA1) (2020) (0)
- How mouse RAG recombinase avoids DNA transposition (2020) (0)
- Issue Information (2021) (0)
- Issue Information (2021) (0)
- ENERGY-REQUIRING ENZYMES THAT MODIFY THE PHYSICAL STRUCTURE OF DNA (1981) (0)
- Re-refined crystal structure of DNA-dependent protein kinase catalytic subunit complexed with Ku80 C-terminal helix (2021) (0)
- CryoEM structure of inactivated-form DNA-PK (Complex III) (2021) (0)
- Cryo-EM structure of activated-form DNA-PK (complex VI) (2021) (0)
- CryoEM structure of DNA-PK catalytic subunit complexed with DNA (Complex II) (2021) (0)
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