Martin Hrabě de Angelis
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Why Is Martin Hrabě de Angelis Influential?
(Suggest an Edit or Addition)According to Wikipedia, Martin Hrabĕ de Angelis is a German geneticist and director of the Institute of Experimental Genetics at Helmholtz Zentrum München and director of the European Mouse Mutant Archive in Monterotondo, Italy. Since 2003 he has held the Chair of Experimental Genetics at Technische Universität München. He is co-founder, speaker and board member of the German Center for Diabetes Research . His research focuses on metabolism and diabetes, large-scale functional genomics/genetics and epigenetics.
Martin Hrabě de Angelis's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Notch signalling controls pancreatic cell differentiation (1999) (1195)
- Identification of Serum Metabolites Associated With Risk of Type 2 Diabetes Using a Targeted Metabolomic Approach (2013) (784)
- Genetics Meets Metabolomics: A Genome-Wide Association Study of Metabolite Profiles in Human Serum (2008) (691)
- Maintenance of somite borders in mice requires the Delta homologue Dll1 (1997) (666)
- Metabolic Footprint of Diabetes: A Multiplatform Metabolomics Study in an Epidemiological Setting (2010) (544)
- Transient and restricted expression during mouse embryogenesis of Dll1, a murine gene closely related to Drosophila Delta. (1995) (493)
- A Humanized Version of Foxp2 Affects Cortico-Basal Ganglia Circuits in Mice (2009) (465)
- Animal models of obesity and diabetes mellitus (2018) (454)
- Cyclooxygenase-2 Controls Energy Homeostasis in Mice by de Novo Recruitment of Brown Adipocytes (2010) (445)
- Aberrant methylation of tRNAs links cellular stress to neuro-developmental disorders (2014) (418)
- Ribosomal mutations cause p53-mediated dark skin and pleiotropic effects (2008) (372)
- Rapamycin extends murine lifespan but has limited effects on aging. (2013) (313)
- The mammalian gene function resource: the international knockout mouse consortium (2012) (277)
- Delta-Notch signaling controls the generation of neurons/glia from neural stem cells in a stepwise process (2003) (273)
- Modulation of the notch signaling by Mash1 and Dlx1/2 regulates sequential specification and differentiation of progenitor cell types in the subcortical telencephalon. (2002) (263)
- Mitochondrial glutathione peroxidase 4 disruption causes male infertility (2009) (260)
- Epigenetic germline inheritance of diet-induced obesity and insulin resistance (2016) (257)
- Targeted estrogen delivery reverses the metabolic syndrome (2012) (247)
- Interaction between Notch signalling and Lunatic fringe during somite boundary formation in the mouse (1999) (246)
- Beethoven, a mouse model for dominant, progressive hearing loss DFNA36 (2002) (242)
- The Notch ligand Jagged1 is required for inner ear sensory development (2001) (214)
- Expression of Delta1 and Serrate1 (Jagged1) in the mouse inner ear (1999) (204)
- Introducing the German Mouse Clinic: open access platform for standardized phenotyping (2005) (192)
- Fibroblast Growth Factor 21—Metabolic Role in Mice and Men (2017) (186)
- Neuronal 3′,3,5-Triiodothyronine (T3) Uptake and Behavioral Phenotype of Mice Deficient in Mct8, the Neuronal T3 Transporter Mutated in Allan–Herndon–Dudley Syndrome (2009) (177)
- Prevalence of sexual dimorphism in mammalian phenotypic traits (2017) (177)
- Effects of G-protein mutations on skin color (2004) (173)
- Oscillating expression of c-Hey2 in the presomitic mesoderm suggests that the segmentation clock may use combinatorial signaling through multiple interacting bHLH factors. (2000) (172)
- Post-publication sharing of data and tools (2009) (166)
- Loss of mitochondrial peptidase Clpp leads to infertility, hearing loss plus growth retardation via accumulation of CLPX, mtDNA and inflammatory factors (2013) (155)
- Effects of ENU dosage on mouse strains (2000) (152)
- Direct production of mouse disease models by embryo microinjection of TALENs and oligodeoxynucleotides (2013) (146)
- Mouse large-scale phenotyping initiatives: overview of the European Mouse Disease Clinic (EUMODIC) and of the Wellcome Trust Sanger Institute Mouse Genetics Project (2012) (140)
- Genetics of dark skin in mice. (2003) (139)
- Chemical Hybridization of Glucagon and Thyroid Hormone Optimizes Therapeutic Impact for Metabolic Disease (2016) (137)
- Neuroprotection after stroke by targeting NOX4 as a source of oxidative stress. (2013) (133)
- Large scale ENU screens in the mouse: genetics meets genomics. (1998) (126)
- Pathophysiology-based subphenotyping of individuals at elevated risk for type 2 diabetes (2020) (125)
- Towards better mouse models: enhanced genotypes, systemic phenotyping and envirotype modelling (2009) (112)
- Distinct signatures of host–microbial meta-metabolome and gut microbiome in two C57BL/6 strains under high-fat diet (2014) (105)
- Creatine improves health and survival of mice (2008) (105)
- Effects of Metformin on Metabolite Profiles and LDL Cholesterol in Patients With Type 2 Diabetes (2015) (103)
- Mouse phenotyping. (2011) (103)
- Restless Legs Syndrome-associated intronic common variant in Meis1 alters enhancer function in the developing telencephalon (2014) (102)
- Circulating Lysophosphatidylcholines Are Markers of a Metabolically Benign Nonalcoholic Fatty Liver (2013) (101)
- Node and midline defects are associated with left-right development in Delta1 mutant embryos (2003) (99)
- Generation and Characterization of dickkopf3 Mutant Mice (2006) (95)
- Erratum: Corrigendum: The European dimension for the mouse genome mutagenesis program (2004) (95)
- Mitochondrial Dysfunction and Decrease in Body Weight of a Transgenic Knock-in Mouse Model for TDP-43* (2014) (94)
- Osteopontin deficiency protects against obesity-induced hepatic steatosis and attenuates glucose production in mice (2011) (93)
- Toxicity modelling of Plk1-targeted therapies in genetically engineered mice and cultured primary mammalian cells (2011) (87)
- Androgen metabolism via 17beta-hydroxysteroid dehydrogenase type 3 in mammalian and non-mammalian vertebrates: comparison of the human and the zebrafish enzyme. (2005) (85)
- Expression of the mouse Delta1 gene during organogenesis and fetal development (1999) (84)
- EuroPhenome: a repository for high-throughput mouse phenotyping data (2009) (84)
- The dominant alopecia phenotypes Bareskin, Rex-denuded, and Reduced Coat 2 are caused by mutations in gasdermin 3. (2004) (82)
- Peri-conceptional obesogenic exposure induces sex-specific programming of disease susceptibilities in adult mouse offspring. (2014) (81)
- Epigenetic alterations in longevity regulators, reduced life span, and exacerbated aging-related pathology in old father offspring mice (2018) (79)
- DJ‐1‐deficient mice show less TH‐positive neurons in the ventral tegmental area and exhibit non‐motoric behavioural impairments (2010) (79)
- eIF6 coordinates insulin sensitivity and lipid metabolism by coupling translation to transcription (2015) (79)
- Calcium Oxalate Stone Formation in the Inner Ear as a Result of an Slc26a4 Mutation*♦ (2010) (77)
- RNA editing of Filamin A pre‐mRNA regulates vascular contraction and diastolic blood pressure (2018) (74)
- The rRNA m6A methyltransferase METTL5 is involved in pluripotency and developmental programs (2020) (74)
- Noncanonical thyroid hormone signaling mediates cardiometabolic effects in vivo (2017) (73)
- N-acyl Taurines and Acylcarnitines Cause an Imbalance in Insulin Synthesis and Secretion Provoking β Cell Dysfunction in Type 2 Diabetes. (2017) (72)
- MFAP4 Promotes Vascular Smooth Muscle Migration, Proliferation and Accelerates Neointima Formation (2016) (71)
- Every-other-day feeding extends lifespan but fails to delay many symptoms of aging in mice (2017) (70)
- The International Mouse Phenotyping Consortium (IMPC): a functional catalogue of the mammalian genome that informs conservation (2018) (68)
- Cytochrome c oxidase subunit 4 isoform 2‐knockout mice show reduced enzyme activity, airway hyporeactivity, and lung pathology (2012) (68)
- Sex-Dependent Susceptibility to Listeria monocytogenes Infection Is Mediated by Differential Interleukin-10 Production (2005) (68)
- Calcineurin Links Mitochondrial Elongation with Energy Metabolism. (2015) (66)
- Distinct regulatory elements direct Delta1 expression in the nervous system and paraxial mesoderm of transgenic mice (2000) (66)
- Pink1-deficiency in mice impairs gait, olfaction and serotonergic innervation of the olfactory bulb (2012) (65)
- Characterization of Phospholipase Cγ Enzymes with Gain-of-Function Mutations* (2009) (65)
- Type 2 diabetes alters metabolic and transcriptional signatures of glucose and amino acid metabolism during exercise and recovery (2015) (65)
- MIM-Induced Membrane Bending Promotes Dendritic Spine Initiation. (2015) (65)
- Mutation in the betaA3/A1-crystallin encoding gene Cryba1 causes a dominant cataract in the mouse. (1999) (65)
- Variations of eye size parameters among different strains of mice (2006) (64)
- Molecular Integration of Incretin and Glucocorticoid Action Reverses Immunometabolic Dysfunction and Obesity. (2017) (64)
- Identification and validation of novel ERBB2 (HER2, NEU) targets including genes involved in angiogenesis (2005) (63)
- Bacterial encapsulins as orthogonal compartments for mammalian cell engineering (2018) (63)
- High-throughput extraction and quantification method for targeted metabolomics in murine tissues (2017) (63)
- The large-scale Munich ENU-mouse-mutagenesis screen (2000) (63)
- Characterization of a mutation in the lens-specific MP70 encoding gene of the mouse leading to a dominant cataract. (2001) (63)
- Oxalate-induced chronic kidney disease with its uremic and cardiovascular complications in C57BL/6 mice. (2016) (62)
- The clinical-chemical screen in the Munich ENU Mouse Mutagenesis Project: screening for clinically relevant phenotypes (2000) (61)
- Electroretinography as a screening method for mutations causing retinal dysfunction in mice. (2004) (61)
- Clinical Chemistry Reference Intervals for C57BL/6J, C57BL/6N, and C3HeB/FeJ Mice (Mus musculus). (2016) (60)
- The German Mouse Clinic: a platform for systemic phenotype analysis of mouse models. (2009) (59)
- Identification of biomarkers for apoptosis in cancer cell lines using metabolomics: tools for individualized medicine (2013) (59)
- Identification of genetic elements in metabolism by high-throughput mouse phenotyping (2018) (58)
- Modeling disease mutations by gene targeting in one-cell mouse embryos (2012) (58)
- LitMiner and WikiGene: identifying problem-related key players of gene regulation using publication abstracts (2005) (58)
- Hyperoxaluria Requires TNF Receptors to Initiate Crystal Adhesion and Kidney Stone Disease. (2017) (58)
- Prdm5 Regulates Collagen Gene Transcription by Association with RNA Polymerase II in Developing Bone (2012) (53)
- Cardiopulmonary dysfunction in the Osteogenesis imperfecta mouse model Aga2 and human patients are caused by bone-independent mechanisms (2012) (52)
- The elevation of circulating fibroblast growth factor 23 without kidney disease does not increase cardiovascular disease risk. (2018) (52)
- Impact of IVC housing on emotionality and fear learning in male C3HeB/FeJ and C57BL/6J mice (2007) (52)
- Specificity assessment from fractionation experiments (SAFE): a novel method to evaluate microarray probe specificity based on hybridisation stringencies. (2003) (51)
- A Myo7a mutation cosegregates with stereocilia defects and low-frequency hearing impairment (2004) (51)
- "Sighted C3H" mice--a tool for analysing the influence of vision on mouse behaviour? (2008) (51)
- IFIT2 Is an Effector Protein of Type I IFN–Mediated Amplification of Lipopolysaccharide (LPS)-Induced TNF-α Secretion and LPS-Induced Endotoxin Shock (2013) (50)
- Metabolic switch during adipogenesis: From branched chain amino acid catabolism to lipid synthesis. (2016) (50)
- Genome-wide analysis of PDX1 target genes in human pancreatic progenitors (2018) (50)
- TGF-β Contributes to Impaired Exercise Response by Suppression of Mitochondrial Key Regulators in Skeletal Muscle (2016) (50)
- Assessing Cognition in Mice (2015) (49)
- Signs of the principle body axes prior to primitive streak formation in the rabbit embryo (1995) (49)
- Voluntary wheel running in mice increases the rate of neurogenesis without affecting anxiety-related behaviour in single tests (2012) (49)
- Characterization of a new, dominant V124E mutation in the mouse alphaA-crystallin-encoding gene. (2001) (48)
- A history of obesity leaves an inflammatory fingerprint in liver and adipose tissue (2017) (48)
- Peroxidasin is essential for eye development in the mouse (2014) (48)
- Visualizing corticotropin‐releasing hormone receptor type 1 expression and neuronal connectivities in the mouse using a novel multifunctional allele (2012) (48)
- Srgap3–/– mice present a neurodevelopmental disorder with schizophrenia‐related intermediate phenotypes (2012) (47)
- EMMA—mouse mutant resources for the international scientific community (2009) (46)
- Mouse Phenotype Database Integration Consortium: integration [corrected] of mouse phenome data resources. (2007) (45)
- Zebrafish 20β-Hydroxysteroid Dehydrogenase Type 2 Is Important for Glucocorticoid Catabolism in Stress Response (2013) (44)
- Large‐Scale N‐Ethyl‐N‐Nitrosourea Mutagenesis of Mice – from Phenotypes to Genes (2000) (44)
- Standards of mouse model phenotyping (2006) (44)
- Isolation and characterization of a novel gene from the DiGeorge chromosomal region that encodes for a mediator subunit. (2001) (44)
- Three novel Pax6 alleles in the mouse leading to the same small-eye phenotype caused by different consequences at target promoters. (2005) (44)
- Systematic selection of housekeeping genes for gene expression normalization in chicken embryo fibroblasts infected with Newcastle disease virus. (2011) (44)
- Metformin Effect on Nontargeted Metabolite Profiles in Patients With Type 2 Diabetes and in Multiple Murine Tissues (2016) (44)
- Neurobeachin, a Regulator of Synaptic Protein Targeting, Is Associated with Body Fat Mass and Feeding Behavior in Mice and Body-Mass Index in Humans (2012) (43)
- A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk (2017) (43)
- A paternal methyl donor-rich diet altered cognitive and neural functions in offspring mice (2017) (43)
- Aey2, a new mutation in the betaB2-crystallin-encoding gene of the mouse. (2001) (43)
- Functional compensation among HMGN variants modulates the DNase I hypersensitive sites at enhancers (2015) (43)
- Epigallocatechin gallate (EGCG) reduces the intensity of pancreatic amyloid fibrils in human islet amyloid polypeptide (hIAPP) transgenic mice (2018) (43)
- Mutation of the Na(+)-K(+)-2Cl(-) cotransporter NKCC2 in mice is associated with severe polyuria and a urea-selective concentrating defect without hyperreninemia. (2010) (41)
- Laboratory mouse housing conditions can be improved using common environmental enrichment without compromising data (2018) (41)
- Alternative oxidase‐mediated respiration prevents lethal mitochondrial cardiomyopathy (2018) (40)
- Apoe, Mbl2, and Psp plasma protein levels correlate with diabetic phenotype in NZO mice--an optimized rapid workflow for SRM-based quantification. (2013) (40)
- Interaction of the MAGUK family member Acvrinp1 and the cytoplasmic domain of the Notch ligand Delta1. (2003) (40)
- High Mobility Group N Proteins Modulate the Fidelity of the Cellular Transcriptional Profile in a Tissue- and Variant-specific Manner* (2013) (40)
- MiR‐34a deficiency accelerates medulloblastoma formation in vivo (2015) (40)
- Cholesterol metabolism promotes B‐cell positioning during immune pathogenesis of chronic obstructive pulmonary disease (2018) (40)
- Cryopreservation of mouse spermatozoa: double your mouse space. (1999) (40)
- Innovations in phenotyping of mouse models in the German Mouse Clinic (2012) (39)
- Cell-based simulation of dynamic expression patterns in the presomitic mesoderm. (2007) (38)
- Reliable recovery of inbred mouse lines using cryopreserved spermatozoa (1999) (38)
- Metformin Supports the Antidiabetic Effect of a Sodium Glucose Cotransporter 2 Inhibitor by Suppressing Endogenous Glucose Production in Diabetic Mice (2014) (38)
- Microphthalmia, parkinsonism, and enhanced nociception in Pitx3416insG mice (2010) (38)
- Angiopoietin-like protein 4 is an exercise-induced hepatokine in humans, regulated by glucagon and cAMP (2017) (38)
- Claudin-12 is not required for blood–brain barrier tight junction function (2019) (38)
- Tests for Anxiety‐Related Behavior in Mice (2015) (37)
- Screening for dysmorphological abnormalities—a powerful tool to isolate new mouse mutants (2000) (37)
- Systematic, standardized and comprehensive neurological phenotyping of inbred mice strains in the German Mouse Clinic (2006) (37)
- Morphologic and molecular characterization of two novel Krt71 (Krt2-6g) mutations: Krt71rco12 and Krt71rco13 (2006) (36)
- Discovery of a novel enzyme mediating glucocorticoid catabolism in fish: 20beta-Hydroxysteroid dehydrogenase type 2 (2012) (36)
- Clinical Chemistry and Other Laboratory Tests on Mouse Plasma or Serum (2013) (36)
- Impact of Temporal Variation on Design and Analysis of Mouse Knockout Phenotyping Studies (2014) (36)
- High fat diet-induced modifications in membrane lipid and mitochondrial-membrane protein signatures precede the development of hepatic insulin resistance in mice (2014) (35)
- Alopecia in a novel mouse model RCO3 is caused by mK6irs1 deficiency. (2003) (35)
- Meis1 coordinates a network of genes implicated in eye development and microphthalmia (2015) (34)
- The biochemical metabolite screen in the Munich ENU Mouse Mutagenesis Project: determination of amino acids and acylcarnitines by tandem mass spectrometry (2000) (34)
- Transcriptional regulation of human and murine 17beta-hydroxysteroid dehydrogenase type-7 confers its participation in cholesterol biosynthesis. (2006) (34)
- Bezafibrate Improves Insulin Sensitivity and Metabolic Flexibility in STZ-Induced Diabetic Mice (2016) (34)
- The Munich MIDY Pig Biobank – A unique resource for studying organ crosstalk in diabetes (2017) (33)
- The CALM and CALM/AF10 interactor CATS is a marker for proliferation (2008) (33)
- Diabetes models by screen for hyperglycemia in phenotype-driven ENU mouse mutagenesis projects. (2008) (33)
- Maternal whole blood cell miRNA-340 is elevated in gestational diabetes and inversely regulated by glucose and insulin (2018) (32)
- Clinical chemistry of human FcRn transgenic mice (2012) (32)
- Retinal proteome alterations in a mouse model of type 2 diabetes (2013) (30)
- Metabolic syndrome and extensive adipose tissue inflammation in morbidly obese Göttingen minipigs (2018) (30)
- V76D mutation in a conserved gD-crystallin region leads to dominant cataracts in mice (2002) (30)
- Immune modulation by Fas ligand reverse signaling: lymphocyte proliferation is attenuated by the intracellular Fas ligand domain. (2011) (30)
- Catweasel mice: A novel role for Six1 in sensory patch development and a model for branchio-oto-renal syndrome (2009) (30)
- Variation of the response to the optokinetic drum among various strains of mice. (2008) (29)
- Genes Whose Gain or Loss-Of-Function Increases Skeletal Muscle Mass in Mice: A Systematic Literature Review (2018) (29)
- Assessment of a systematic expression profiling approach in ENU-induced mouse mutant lines (2004) (29)
- New mouse models for metabolic bone diseases generated by genome-wide ENU mutagenesis (2012) (28)
- Conditional Reduction of Adult Born Doublecortin-Positive Neurons Reversibly Impairs Selective Behaviors (2015) (27)
- Bezafibrate ameliorates diabetes via reduced steatosis and improved hepatic insulin sensitivity in diabetic TallyHo mice (2017) (27)
- Comet assay as a tool to screen for mouse models with inherited radiation sensitivity (2000) (27)
- Centralized mouse repositories (2012) (27)
- Long-term proteasomal inhibition in transgenic mice by UBB+1 expression results in dysfunction of central respiration control reminiscent of brainstem neuropathology in Alzheimer patients (2012) (27)
- Comparison of particle-exposure triggered pulmonary and systemic inflammation in mice fed with three different diets (2011) (26)
- From Dynamic Expression Patterns to Boundary Formation in the Presomitic Mesoderm (2012) (26)
- Overexpressed vs mutated Kras in murine fibroblasts: a molecular phenotyping study (2009) (26)
- Nutrition and its role in epigenetic inheritance of obesity and diabetes across generations (2020) (25)
- Risk Assessment of Mouse Hepatitis Virus Infection via In Vitro Fertilization and Embryo Transfer by the Use of Zona-Intact and Laser-Microdissected Oocytes1 (2006) (25)
- New Mutation in the Mouse Xpd/Ercc2 Gene Leads to Recessive Cataracts (2015) (25)
- Meis1: effects on motor phenotypes and the sensorimotor system in mice (2017) (25)
- Exome sequencing identifies a nonsense mutation in Fam46a associated with bone abnormalities in a new mouse model for skeletal dysplasia (2016) (24)
- The chemotherapeutic agents nocodazole and amsacrine cause meiotic delay and non-disjunction in spermatocytes of mice. (2008) (24)
- Type of uromodulin mutation and allelic status influence onset and severity of uromodulin-associated kidney disease in mice. (2013) (24)
- Growth hormone receptor knockout to reduce the size of donor pigs for preclinical xenotransplantation studies (2020) (24)
- An ENU-induced mutation in AP-2α leads to middle earand ocular defects in Doarad mice (2004) (23)
- Effects of diet-matrix on volatile organic compounds in breath in diet-induced obese mice (2014) (23)
- Generation of N-ethyl-N-nitrosourea-induced mouse mutants with deviations in hematological parameters (2011) (23)
- Pathophysiology-based subphenotyping of individuals at elevated risk for type 2 diabetes (2021) (23)
- Longitudinal fundus and retinal studies with SD-OCT: a comparison of five mouse inbred strains (2013) (23)
- Knock-out of nexilin in mice leads to dilated cardiomyopathy and endomyocardial fibroelastosis (2015) (23)
- Identification of immunological relevant phenotypes in ENU mutagenized mice (2000) (22)
- A Mutation in the Enamelin Gene in a Mouse Model (2007) (22)
- Neuron-specific inactivation of Wt1 alters locomotion in mice and changes interneuron composition in the spinal cord (2018) (22)
- MausDB: An open source application for phenotype data and mouse colony management in large-scale mouse phenotyping projects (2008) (22)
- Gain-of-function mutations in a member of the Src family kinases cause autoinflammatory bone disease in mice and humans (2019) (22)
- An approach to handling and interpretation of ambiguous data in transcriptome and proteome comparisons (2008) (22)
- Blood Collection from Mice and Hematological Analyses on Mouse Blood (2013) (22)
- The Role of Eif6 in Skeletal Muscle Homeostasis Revealed by Endurance Training Co-expression Networks (2017) (22)
- New ENU-induced semidominant mutation, Ali18, causes inflammatory arthritis, dermatitis, and osteoporosis in the mouse (2006) (22)
- Male offspring born to mildly ZIKV-infected mice are at risk of developing neurocognitive disorders in adulthood (2018) (21)
- The effect of differentiation and TGFβ on mitochondrial respiration and mitochondrial enzyme abundance in cultured primary human skeletal muscle cells (2018) (21)
- Generation of N‐ethyl‐N‐nitrosourea‐induced mouse mutants with deviations in plasma enzyme activities as novel organ‐specific disease models (2009) (21)
- The transcription factor Smad-interacting protein 1 controls pain sensitivity via modulation of DRG neuron excitability (2011) (21)
- Identification of Dll1 (Delta1) target genes during mouse embryogenesis using differential expression profiling. (2005) (21)
- Hepatic Rab24 controls blood glucose homeostasis via improving mitochondrial plasticity (2019) (21)
- Crybb2 coding for βB2-crystallin affects sensorimotor gating and hippocampal function (2013) (21)
- An ENU mutagenesis-derived mouse model with a dominant Jak1 mutation resembling phenotypes of systemic autoimmune disease. (2013) (21)
- Large-scale mutational analysis for the annotation of the mouse genome. (2002) (21)
- The hepatic phosphatidylcholine transporter ABCB4 as modulator of glucose homeostasis (2012) (21)
- Ligand‐independent epidermal growth factor receptor hyperactivation increases sebaceous gland size and sebum secretion in mice (2013) (20)
- The Role of Fibroblast Growth Factor-Binding Protein 1 in Skin Carcinogenesis and Inflammation. (2018) (20)
- Micro-imaging of Brain Cancer Radiation Therapy Using Phase-contrast Computed Tomography. (2018) (20)
- MouseNet© database: digital management of a large-scale mutagenesis project (2000) (20)
- Dll1 Haploinsufficiency in Adult Mice Leads to a Complex Phenotype Affecting Metabolic and Immunological Processes (2009) (20)
- DLL1- and DLL4-Mediated Notch Signaling Is Essential for Adult Pancreatic Islet Homeostasis (2020) (20)
- EMMA--the European mouse mutant archive. (2007) (20)
- Integration of Mouse Phenome Data Resources (2008) (19)
- Identification of a Keratin 4 mutation in a chemically induced mouse mutant that models white sponge nevus. (2007) (19)
- No Amelioration of Uromodulin Maturation and Trafficking Defect by Sodium 4-Phenylbutyrate in Vivo (2014) (19)
- Screening for Bone and Cartilage Phenotypes in Mice (2008) (19)
- IMMOTILE CILIA SYNDROME: RADIAL SPOKES DEFICIENCY IN A PATIENT WITH KARTAGENER'S TRIAD (1981) (19)
- Understanding gene functions and disease mechanisms: Phenotyping pipelines in the German Mouse Clinic (2017) (19)
- High-throughput phenotypic assessment of cardiac physiology in four commonly used inbred mouse strains (2014) (19)
- A review of standardized metabolic phenotyping of animal models (2014) (19)
- Activated macrophages control human adipocyte mitochondrial bioenergetics via secreted factors (2017) (19)
- First mutation in the βA2-crystallin encoding gene is associated with small lenses and age-related cataracts. (2011) (19)
- Combination of in silico and in situ hybridisation approaches to identify potential Dll1 associated miRNAs during mouse embryogenesis. (2010) (19)
- Myoscape controls cardiac calcium cycling and contractility via regulation of L-type calcium channel surface expression (2016) (19)
- Improved efficacy of allergen-specific immunotherapy by JAK inhibition in a murine model of allergic asthma (2017) (18)
- INFRAFRONTIER: a European resource for studying the functional basis of human disease (2016) (18)
- Glucose Tolerance Tests for Systematic Screening of Glucose Homeostasis in Mice (2015) (18)
- Sphingomyelin Synthase 1 Is Essential for Male Fertility in Mice (2016) (17)
- hIAPP forms toxic oligomers in plasma. (2018) (17)
- Mesenchymal TNFR2 promotes the development of polyarthritis and comorbid heart valve stenosis. (2018) (17)
- Overexpression of the anti-apoptotic protein AVEN contributes to increased malignancy in hematopoietic neoplasms (2013) (16)
- Faim2 contributes to neuroprotection by erythropoietin in transient brain ischemia (2018) (16)
- Impact of fibroblast growth factor 21 on the secretome of human perivascular preadipocytes and adipocytes: a targeted proteomics approach (2016) (16)
- Online breath gas analysis in unrestrained mice by hs-PTR-MS (2014) (16)
- Point mutation of Ffar1 abrogates fatty acid-dependent insulin secretion, but protects against HFD-induced glucose intolerance (2017) (16)
- Machine Learning Approaches Reveal Metabolic Signatures of Incident Chronic Kidney Disease in Individuals With Prediabetes and Type 2 Diabetes (2020) (16)
- Modeling coexistence of oscillation and Delta/Notch-mediated lateral inhibition in pancreas development and neurogenesis. (2017) (15)
- Phosphorylation Control of p53 DNA-Binding Cooperativity Balances Tumorigenesis and Aging (2020) (15)
- Genes Whose Gain or Loss-of-Function Increases Endurance Performance in Mice: A Systematic Literature Review (2019) (15)
- High levels of eukaryotic Initiation Factor 6 (eIF6) are required for immune system homeostasis and for steering the glycolytic flux of TCR-stimulated CD4+ T cells in both mice and humans. (2017) (15)
- CIP2A Promotes T-Cell Activation and Immune Response to Listeria monocytogenes Infection (2016) (15)
- Hyperexcitable interneurons trigger cortical spreading depression in an Scn1a migraine model (2021) (15)
- Promotion of gastrulation by maternal growth factor in cultured rabbit blastocysts (1995) (15)
- Prdm6 Is Essential for Cardiovascular Development In Vivo (2013) (15)
- Lens density tracking in mice by Scheimpflug imaging (2013) (15)
- High-throughput discovery of genetic determinants of circadian misalignment (2020) (15)
- Novel lymphocyte-independent mechanisms to initiate inflammatory arthritis via bone marrow-derived cells of Ali18 mutant mice. (2007) (14)
- Power matters in closing the phenotyping gap (2007) (14)
- Night Shift Work Affects Urine Metabolite Profiles of Nurses with Early Chronotype (2018) (14)
- Smad‐interacting protein 1 affects acute and tonic, but not chronic pain (2014) (14)
- RNase H2 Loss in Murine Astrocytes Results in Cellular Defects Reminiscent of Nucleic Acid-Mediated Autoinflammation (2018) (14)
- Functional genome analysis indicates loss of 17beta-hydroxysteroid dehydrogenase type 2 enzyme in the zebrafish (2007) (13)
- Generation and Standardized, Systemic Phenotypic Analysis of Pou3f3L423P Mutant Mice (2016) (13)
- Diet-induced and mono-genetic obesity alter volatile organic compound signature in mice (2016) (13)
- Prediction of Glucose Tolerance without an Oral Glucose Tolerance Test (2018) (13)
- Serum Response Factor (SRF) Ablation Interferes with Acute Stress-Associated Immediate and Long-Term Coping Mechanisms (2016) (13)
- Pharmacogenetics of oral antidiabetic therapy. (2018) (13)
- Dexamethasone treatment alters insulin, leptin, and adiponectin levels in male mice as observed in DIO but does not lead to alterations of metabolic phenotypes in the offspring (2015) (13)
- A phenotype-driven ENU mutagenesis screen for the identification of dominant mutations involved in alcohol consumption (2008) (12)
- Effect of IVF and laser zona dissection on DNA methylation pattern of mouse zygotes (2009) (12)
- Preadipocytes of obese humans display gender-specific bioenergetic responses to glucose and insulin (2018) (12)
- Female mice lacking Pald1 exhibit endothelial cell apoptosis and emphysema (2017) (12)
- A comprehensive and comparative phenotypic analysis of the collaborative founder strains identifies new and known phenotypes (2020) (12)
- Obesity and Impaired Metabolic Health Increase Risk of COVID-19-Related Mortality in Young and Middle-Aged Adults to the Level Observed in Older People: The LEOSS Registry (2022) (12)
- Mouse mutant phenotyping at scale reveals novel genes controlling bone mineral density (2020) (12)
- Analysis of locomotor behavior in the German Mouse Clinic (2017) (12)
- Spectral domain - Optical coherence tomography (SD-OCT) as a monitoring tool for alterations in mouse lenses. (2019) (12)
- Great times for mouse genetics: getting ready for large-scale ENU-mutagenesis (2000) (12)
- Phenotypic and pathomorphological characteristics of a novel mutant mouse model for maturity-onset diabetes of the young type 2 (MODY 2). (2010) (11)
- Mild maternal hyperglycemia in INSC93S transgenic pigs causes impaired glucose tolerance and metabolic alterations in neonatal offspring (2019) (11)
- Cognitive impairment and autistic-like behaviour in SAPAP4-deficient mice (2019) (11)
- Increased estrogen to androgen ratio enhances immunoglobulin levels and impairs B cell function in male mice (2020) (11)
- A new Fgf10 mutation in the mouse leads to atrophy of the harderian gland and slit-eye phenotype in heterozygotes: a novel model for dry-eye disease? (2009) (11)
- Modification of the fatty acid composition of an obesogenic diet improves the maternal and placental metabolic environment in obese pregnant mice. (2017) (11)
- Dose-dependent long-term effects of a single radiation event on behaviour and glial cells (2020) (11)
- Creatine improves health and survival in mice (2007) (11)
- Crybb2 Mutations Consistently Affect Schizophrenia Endophenotypes in Mice (2018) (11)
- Abca3 haploinsufficiency is a risk factor for lung injury induced by hyperoxia or mechanical ventilation in a murine model (2013) (11)
- Gender-, strain-, and inheritance-dependent variation in aldosterone secretion in mice. (2012) (10)
- Dilution correction for dynamically influenced urinary analyte data. (2018) (10)
- Systematic phenotyping of mouse mutants (2010) (10)
- Phylogenetic relationships of the bumblebees Bombus moderatus, B. albocinctus, B. burjaeticus, B. florilegus and B. cryptarum based on mitochondrial DNA markers: a complex of closely related taxa with circumpolar distribution (Hymenoptera: Apidae: Bombus). (2010) (10)
- Aey 2 , a New Mutation in the b B 2-Crystallin – Encoding Gene of the Mouse (2001) (10)
- The BEACH protein LRBA is required for hair bundle maintenance in cochlear hair cells and for hearing (2017) (10)
- Chemical Mutagenesis in Mice (2007) (10)
- Overexpression of the mitochondrial methyltransferase TFB1M in the mouse does not impact mitoribosomal methylation status or hearing (2015) (9)
- A Vitamin E-Enriched Antioxidant Diet Interferes with the Acute Adaptation of the Liver to Physical Exercise in Mice (2018) (9)
- Fgf9Y162C Mutation Alters Information Processing and Social Memory in Mice (2017) (9)
- Molecular Phenotyping of Mouse Mutant Resources by RNA Expression Profiling (2002) (9)
- In vitro fertilization/cryopreservation. (2003) (9)
- Glucose tolerance and insulin sensitivity define adipocyte transcriptional programs in human obesity (2018) (9)
- Cited4 is a sex‐biased mediator of the antidiabetic glitazone response in adipocyte progenitors (2018) (9)
- Defective immuno- and thymoproteasome assembly causes severe immunodeficiency (2018) (9)
- Large-scale Production of Mouse Phenotypes: the Search for Animal Models for Inherited M. Diseases in Humans (2001) (9)
- Artefacts and Reliability of DNA Microarray Expression Profiling Data (2003) (9)
- Fast Synchronization of Ultradian Oscillators Controlled by Delta-Notch Signaling with Cis-Inhibition (2014) (8)
- The First Scube3 Mutant Mouse Line with Pleiotropic Phenotypic Alterations (2016) (8)
- Phenotypic characterization of mouse models for bone-related diseases in the German Mouse Clinic. (2008) (8)
- Liver lipid metabolism is altered by increased circulating estrogen to androgen ratio in male mouse. (2016) (8)
- Targeted Disruption of the Mouse Npal3 Gene Leads to Deficits in Behavior, Increased IgE Levels, and Impaired Lung Function (2009) (8)
- Large-Scale Albuminuria Screen for Nephropathy Models in Chemically Induced Mouse Mutants (2005) (8)
- Long-term experiment to study the development, interaction, and influencing factors of DEXA parameters (2013) (8)
- High-throughput extraction and quantification method for targeted metabolomics in murine tissues (2017) (8)
- Mildly compromised tetrahydrobiopterin cofactor biosynthesis due to Pts variants leads to unusual body fat distribution and abdominal obesity in mice (2016) (8)
- Standardized, systemic phenotypic analysis reveals kidney dysfunction as main alteration of Kctd1I27N mutant mice (2017) (8)
- Fibroblast growth factor induces primitive streak formation in rabbit pre-implantation embryos in vitro (1993) (8)
- Uromodulin Retention in Thick Ascending Limb of Henle's Loop Affects SCD1 in Neighboring Proximal Tubule: Renal Transcriptome Studies in Mouse Models of Uromodulin-Associated Kidney Disease (2014) (8)
- Novel small-eye allele in paired box gene 6 (Pax6) is caused by a point mutation in intron 7 and creates a new exon (2013) (7)
- Standardized, Systemic Phenotypic Analysis of Umod C93F and Umod A227T Mutant Mice (2013) (7)
- Mouse phenotype database integration consortium: Integration of mouse phenome data resources (vol 18, pg 157, 2007) (2007) (7)
- A phylogenetic framework for the North American bumblebee species of the subgenus Bombus sensu stricto (Bombus affinis, B. franklini, B. moderatus, B. occidentalis & B. terricola) based on mitochondrial DNA markers. (Hymenoptera: Apidae: Bombus). (2010) (7)
- Utilization of a mutagenesis screen to generate mouse models of hyperaldosteronism. (2011) (7)
- EUMORPHIA and the European Mouse Phenotyping Resource for Standardized Screens (EMPReSS) (2006) (7)
- Disruption of paternal circadian rhythm affects metabolic health in male offspring via nongerm cell factors (2021) (7)
- Microphakia and congenital cataract formation in a novel Lim2C51R mutant mouse (2011) (7)
- Genetic and Molecular Insights Into Genotype‐Phenotype Relationships in Osteopathia Striata With Cranial Sclerosis (OSCS) Through the Analysis of Novel Mouse Wtx Mutant Alleles (2018) (6)
- Mitochondrial function, dysfunction, and adaption in the liver during the development of diabetes. (2015) (6)
- Chorionic gonadotropin-like proteins in the obplacental giant cells of the rabbit (1994) (6)
- Corrigendum: High-throughput discovery of novel developmental phenotypes (2017) (6)
- A Polygenic Risk Score of Lipolysis-Increasing Alleles Determines Visceral Fat Mass and Proinsulin Conversion (2019) (6)
- AMPK subunits harbor largely non-overlapping genetic determinants for body fat mass, glucose- and cholesterol metabolism. (2019) (6)
- Amelogenesis Imperfecta in a New Animal Model—a Mutation in Chromosome 5 (human 4q21) (2004) (6)
- Soft windowing application to improve analysis of high-throughput phenotyping data (2019) (6)
- Generation of Mice Lacking DUF1220 Protein Domains: Effects on Fecundity and Hyperactivity (2015) (6)
- A truncating Aspm allele leads to a complex cognitive phenotype and region-specific reductions in parvalbuminergic neurons (2020) (6)
- Publisher Correction: Extensive identification of genes involved in congenital and structural heart disorders and cardiomyopathy (2022) (6)
- Large-scale production of mouse phenotypes: the search for animal models for inherited diseases in humans. (2001) (6)
- Longitudinal Frequencies of Blood Leukocyte Subpopulations Differ between NOD and NOR Mice but Do Not Predict Diabetes in NOD Mice (2016) (6)
- Enhanced oxidative stress and endocrine pancreas alterations are linked to a novel glucokinase missense mutation in ENU-derived Munich Gck D217V mutants (2012) (6)
- Increased Expressions of Matrix Metalloproteinases (MMPs) in Prostate Cancer Tissues of Men with Type 2 Diabetes (2020) (5)
- Ectopic fat accumulation in human astrocytes impairs insulin action (2020) (5)
- Dusp8 affects hippocampal size and behavior in mice and humans (2019) (5)
- Cox4i2, Ifit2, and Prdm11 Mutant Mice: Effective Selection of Genes Predisposing to an Altered Airway Inflammatory Response from a Large Compendium of Mutant Mouse Lines (2015) (5)
- Genome wide conditional mouse knockout resources (2016) (5)
- Generation of ENU-Induced Mouse Mutants with Hypocholesterolemia: Novel Tools for Dissecting Plasma Lipoprotein Homeostasis (2007) (5)
- iTAG-RNA Isolates Cell-Specific Transcriptional Responses to Environmental Stimuli and Identifies an RNA-Based Endocrine Axis. (2020) (5)
- Placental lactogen-like proteins in the rabbit placenta (1993) (5)
- A Fast, Easy, and Customizable Eight‐Color Flow Cytometric Method for Analysis of the Cellular Content of Bronchoalveolar Lavage Fluid in the Mouse (2017) (5)
- Streptozotocin-induced β-cell damage, high fat diet, and metformin administration regulate Hes3 expression in the adult mouse brain (2018) (5)
- Exercise prevents fatty liver by modifying the compensatory response of mitochondrial metabolism to excess substrate availability (2021) (5)
- The (not so) Controversial Role of DNA Methylation in Epigenetic Inheritance Across Generations (2020) (5)
- Biomedical Research Goes Viral: Dangers and Opportunities (2020) (5)
- PAX6 mutation alters circadian rhythm and β cell function in mice without affecting glucose tolerance (2020) (4)
- Genome-wide search for genes that modulate inflammatory arthritis caused by Ali18 mutation in mice (2009) (4)
- Susceptibility to diet-induced obesity at thermoneutral conditions is independent of UCP1. (2021) (4)
- Differential Effects of Insulin-Deficient Diabetes Mellitus on Visceral vs. Subcutaneous Adipose Tissue—Multi-omics Insights From the Munich MIDY Pig Model (2021) (4)
- We need more mutants: Plans for a large scale ENU mouse mutagenesis screen (1998) (4)
- Genetic characterization of a mouse line with primary aldosteronism. (2017) (4)
- TGF-β Induction of miR-143/145 Is Associated to Exercise Response by Influencing Differentiation and Insulin Signaling Molecules in Human Skeletal Muscle (2021) (4)
- CIN 85 regulates dopamine receptor endocytosis and governs behavior in mice (2010) (4)
- Hypercholesterolemia in ENU-induced mouse mutants (2004) (4)
- Mutation in the mouse histone gene Hist2h3c1 leads to degeneration of the lens vesicle and severe microphthalmia (2019) (3)
- The production of 4,182 mouse lines identifies experimental and biological variables impacting Cas9-mediated mutant mouse line production (2021) (3)
- N-ethyl-N-nitrosourea mutagenesis produced a small number of mice with altered plasma electrolyte levels (2009) (3)
- A point mutation in the Pdia6 gene results in loss of pancreatic β-cell identity causing overt diabetes (2021) (3)
- A new design for a micro-CT scanner (2009) (3)
- The German Mouse Clinic – Running an Open Access Platform (2011) (3)
- Emergency prevention of extinction of a transgenic allele in a less-fertile transgenic mouse line by crossing with an inbred or outbred mouse strain coupled with assisted reproductive technologies. (2007) (3)
- Erratum to: New mouse models for metabolic bone diseases generated by genome-wide ENU mutagenesis (2014) (3)
- Monday, 27 August 2012 (2012) (3)
- Big data in large-scale systemic mouse phenotyping (2017) (3)
- Costs of Implementing Quality in Research Practice. (2019) (3)
- Systematic Screening for Mutant Mouse Lines with Defects in Body Temperature Regulation (2012) (3)
- Animal models of obesity and diabetes (2018) (3)
- Characterization of spontaneous airspace enlargement in mice lacking microfibrillar-1 associated protein 4 2 (2015) (3)
- Effects of rilopirox on rabbit blastocysts in a protein-free in vitro culture under different culture conditions. (1994) (3)
- [Characterization of ENU-mutant mice. Animal models for human diseases using morphological and molecular methods]. (2010) (3)
- EGFR ligands exert diverging effects on male reproductive organs. (2010) (3)
- Titan Mice are Unique Short-Lived mammalian model of metabolic syndrome and aging (2020) (2)
- DISCOVERY AND FUNCTIONAL CHARACTERIZATION OF NEW GENES BY LARGE SCALE ENU MUTAGENESIS IN MICE (1999) (2)
- In Vitro Characterization Of TNSALP Mutations From Two Novel Mouse Models For Hypophosphatasia (2012) (2)
- Screen for alterations of iron related parameters in N-ethyl-N-nitrosourea-treated mice identified mutant lines with increased plasma ferritin levels (2015) (2)
- Integration of Mouse Phenome Data Resources The Mouse Phenotype Database Integration Consortium * (2007) (2)
- FGF21 inhibits adiponectin secretion in human adipocytes (2014) (2)
- Biallelic loss-of-function variants in RABGAP1 cause a novel neurodevelopmental syndrome. (2022) (2)
- Infrafrontier - Mouse models and phenotyping data for the European biomedical research community (2009) (2)
- High throughput phenotyping of left and right ventricular cardiomyopathy in calcineurin transgene mice (2015) (2)
- Characterising a homozygous two‐exon deletion in UQCRH: comparing human and mouse phenotypes (2021) (2)
- Dexamethasone treatment alters insulin, leptin, and adiponectin levels in male mice as observed in DIO but does not lead to alterations of metabolic phenotypes in the offspring (2015) (2)
- Haplotypes, median networks, and diagnostic characters as tools to elucidate the intraspecific genetic and taxonomic structure of bumblebees, with a description of Bombus cryptarum pallidocinctus new subspecies (Hymenoptera: Apidae: Bombus). (2014) (2)
- Mouse Genetics and Metabolic Mouse Phenotyping (2012) (2)
- Development and quality characterization of a novel CT system (2010) (1)
- Measuring and Interpreting Oxygen Consumption Rates in Whole Fly Head Segments. (2019) (1)
- Erratum to: High throughput phenotyping of left and right ventricular cardiomyopathy in calcineurin transgene mice (2015) (1)
- Ex-vivo assessment and non-invasive in vivo imaging of internal hemorrhages in Aga2/+ mutant mice. (2013) (1)
- PATHBIO: an international training program for precision mouse phenotyping (2020) (1)
- Bmpr1b Splice Site Mutation Leads To Optic Nerve Head Degeneration In The Mouse (2012) (1)
- Nutrition and its role in epigenetic inheritance of obesity and diabetes across generations (2020) (1)
- In vitro analysis of bone phenotypes in Col1a1 and Jagged1 mutant mice using a standardized osteoblast cell culture system (2013) (1)
- New mouse models and mechanisms for bone and cartilage disorders (2009) (1)
- X-ray multiscale 3D neuroimaging to quantify cellular aging and neurodegeneration postmortem in a model of Alzheimer’s disease (2022) (1)
- INFRAFRONTIER quality principles in systemic phenotyping (2021) (1)
- Nox4 Maintains Blood Pressure during Low Sodium Diet (2021) (1)
- Validation of Mct8/Oatp1c1 dKO mice as a model organism for the Allan-Herndon-Dudley Syndrome (2022) (1)
- Seizures, ataxia and parvalbumin-expressing interneurons respond to selenium supply in Selenop-deficient mice (2022) (1)
- Thermosensitive PLGA–PEG–PLGA Hydrogel as Depot Matrix for Allergen-Specific Immunotherapy (2022) (1)
- Online breath gas analysis in unrestrained mice by hs-PTR-MS (2013) (1)
- Mutation in Pxdn encoding peroxidasin causes small lenses and kinky tails in the mouse (2011) (1)
- Unbiased analysis of obesity related, fat depot specific changes of adipocyte volumes and numbers using light sheet fluorescence microscopy (2021) (1)
- Extensive identification of genes involved in congenital and structural heart disorders and cardiomyopathy (2022) (1)
- AMPK subunits harbor largely non-overlapping genetic determinants for body fat mass, glucose- and cholesterol metabolism. (2019) (1)
- Introduction to Mammalian Genome Special Issue: Epigenetics (2020) (1)
- Innovations in phenotyping of mouse models in the German Mouse Clinic (2012) (1)
- N471D WASH complex subunit strumpellin knock‐in mice display mild motor and cardiac abnormalities and BPTF and KLHL11 dysregulation in brain tissue (2021) (1)
- 179Importance of embryo transfers in transgenic mouse facilities (2004) (1)
- INFRAFRONTIER: a European resource for studying the functional basis of human disease (2016) (1)
- Diabetes type 2 risk gene Dusp8 is associated with altered sucrose reward behavior in mice and humans (2020) (1)
- Voluntary wheel running in mice increases the rate of neurogenesis without affecting anxiety-related behaviour in single tests (2012) (1)
- Constitutive activation of Jak1 leads to increased fibroblast growth factor 23 levels in mice (2019) (1)
- Crybb2 coding for βB2-crystallin affects sensorimotor gating and hippocampal function (2013) (1)
- First genetically characterized mouse model for age‐related cataracts is a mutation in the bA2‐crystallin encoding gene (2010) (1)
- A review of standardized metabolic phenotyping of animal models (2014) (0)
- New mouse models for metabolic bone diseases generated by genome-wide ENU mutagenesis (2012) (0)
- Long-term experiment to study the development, interaction, and influencing factors of DEXA parameters (2013) (0)
- PAX6 mutation alters circadian rhythm and β cell function in mice without affecting glucose tolerance (2020) (0)
- Identification of genetic elements in metabolism by high-throughput mouse phenotyping (2018) (0)
- Mouse large-scale phenotyping initiatives: overview of the European Mouse Disease Clinic (EUMODIC) and of the Wellcome Trust Sanger Institute Mouse Genetics Project (2012) (0)
- Author Correction: Maternal whole blood cell miRNA-340 is elevated in gestational diabetes and inversely regulated by glucose and insulin (2022) (0)
- Deletion of SERF2 in mice delays embryonic development and alters amyloid deposit structure in the brain (2023) (0)
- Every-other-day feeding extends lifespan but fails to delay many symptoms of aging in mice (2017) (0)
- Female mice lacking Pald1 exhibit endothelial cell apoptosis and emphysema (2017) (0)
- Screen for alterations of iron related parameters in N-ethyl-N-nitrosourea-treated mice identified mutant lines with increased plasma ferritin levels (2015) (0)
- Author Correction: EMPReSS: standardized phenotype screens for functional annotation of the mouse genome (2022) (0)
- Defective immuno- and thymoproteasome assembly causes severe immunodeficiency (2018) (0)
- BALB-Abcb4 mice lacking the hepatobiliary phospholipid transporter represent a potential model of hepatic osteodystrophy (2009) (0)
- 1098 MODELLING HEPATIC OSTEODYSTROPHY: BALB-ABCB4 KNOCKOUT MICE LACKING THE HEPATOBILIARY PHOSPHOLIPID TRANSPORTER DISPLAY DECREASED 25-OH-VITAMIN D3 SERUM LEVELS AND BONE MINERAL CONTENTS (2010) (0)
- The hepatic ABCB4 transporter for phosphatidylcholine as novel modulator of glucose homoestasis (2010) (0)
- Dll1-and Dll4-mediated Notch signalling in adult pancreatic beta cells is essential for the structural integrity of islets and maintenance of glucose homeostasis. (2016) (0)
- CHAPTER 4 – Mouse Genomics (2004) (0)
- Modelling hepatic osteodystrophy: BALB-Abcb4 knockout mice lacking the hepatobiliary phospholipid transporter display decreased 25-OH-vitamin D3 serum levels and bone mineral contents (2010) (0)
- Plasma proteomic profiles in prediabetes reversing to normoglycemia or progressing to diabetes in a year – a cross-sectional and prospective analysis (2023) (0)
- Impaired glucose tolerance in newborn piglets exposed to mild hyperglycemia in utero (2017) (0)
- INFRAFRONTIER quality principles in systemic phenotyping (2021) (0)
- Cholestatic ABCB4-deficient mice reveal depression/anxiety-like behavior (2013) (0)
- Epigallocatechin gallate (EGCG) reduces the intensity of pancreatic amyloid fibrils in human islet amyloid polypeptide (hIAPP) transgenic mice (2018) (0)
- Dietary digestible carbohydrates are associated with higher prevalence of asthma in humans and with aggravated lung allergic inflammation in mice (2022) (0)
- alters enhancer function in the developing telencephalon Meis 1 Restless Legs Syndrome-associated intronic common variant in Material Supplemental (2014) (0)
- Standardized, systemic phenotypic analysis reveals kidney dysfunction as main alteration of Kctd1I27N mutant mice (2017) (0)
- Male offspring born to mildly ZIKV-infected mice are at risk of developing neurocognitive disorders in adulthood (2018) (0)
- Identifying causal serum protein–cardiometabolic trait relationships using whole genome sequencing (2022) (0)
- The occurrence of tarsal injuries in male mice of C57BL/6N substrains in multiple international mouse facilities (2020) (0)
- Fgf9Y162C Mutation Alters Information Processing and Social Memory in Mice (2017) (0)
- TGFß regulates metabolism of human skeletal muscle cells by miRNAs (2018) (0)
- From Developmental Biology to Developmental Toxicology (2000) (0)
- Abstract PR16: Important bidirectional function in the Notch-Delta signaling in pancreatic carcinogenesis and metastasis (2011) (0)
- Centralized mouse repositories (2012) (0)
- The mammalian gene function resource: the international knockout mouse consortium (2012) (0)
- Analysis of the sex-specific variability of blood parameters in C3H inbred mice by using data from a long-term, high-throughput project. (2021) (0)
- Phenotypic Analysis of a New Mouse Model for Genetic Deafness: “Hush Puppy” (2003) (0)
- Correction to: The International Mouse Phenotyping Consortium (IMPC): a functional catalogue of the mammalian genome that informs conservation (2019) (0)
- a Mutation in Chromosome 5 ( human 4 q 21 ) − − Amelogenesis Imperfecta in a New Animal Model (0)
- In-vivo targeted tagging of RNA isolates cell specific transcriptional responses to environmental stimuli and identifies liver-to-adipose RNA transfer (2019) (0)
- A mouse model for human-specific changes in FOXP2, a gene important for speech and language. (2007) (0)
- Mesp2 expression without Ripply2 . (2012) (0)
- A comprehensive and comparative phenotypic analysis of the collaborative founder strains identifies new and known phenotypes (2020) (0)
- Phenotyping of Host-Pathogen Interactions in Mice (2006) (0)
- Compartmentalised expression of in epithelial somites is required for the formation of intervertebral joints-4 (2011) (0)
- Circadian locomotor activity in Meis1 knock-out mice (2017) (0)
- Mutation in the Bmpr1b gene affects optic nerve development (2010) (0)
- Mice with point mutations in Ffar1 display impaired glucose tolerance (2014) (0)
- Maternal whole blood cell miRNA-340 is elevated in gestational diabetes and inversely regulated by glucose and insulin (2018) (0)
- The INFRAFRONTIER research infrastructure and EMMA: The European mouse mutant archive. (2014) (0)
- Impact of IVC housing on emotionality and fear learning in male C 3 H and B 6 J mice (2006) (0)
- Bacterial encapsulins as orthogonal compartments for mammalian cell engineering (2018) (0)
- Growth hormone receptor-deficient pigs resemble the pathophysiology of human Laron syndrome (2018) (0)
- Systemic metabolic effects exerted by a point mutation in the RED subdomain of PAX6. (2016) (0)
- Abstract A55: Dual role of the Notch ligand Delta-1 in pancreatic carcinogenesis and metastasis. (2012) (0)
- Crybb2 Mutations Consistently Affect Schizophrenia Endophenotypes in Mice (2018) (0)
- Comprehensive phenotypic characterization of ABCB4 deficient mice reveals systemic effects of spontaneous biliary fibrosis (2009) (0)
- Distinct Morphological and Behavioural Alterations in ENU-Induced Heterozygous Trpc7K810Stop Mutant Mice (2021) (0)
- Extrahepatic manifestations of ATP-binding cassette transporter B4 (ABCB4) deficiency detected in a systematic phenomics platform (2014) (0)
- The International Mouse Phenotyping Consortium (IMPC): a functional catalogue of the mammalian genome that informs conservation (2018) (0)
- 10-28 Ali14, a Novel Gain-of-Function Mutation in Phospholipase C gamma 2, Causes Inflammatory Arthritis in the Mouse (2010) (0)
- Erratum (2009) (0)
- PATHBIO: an international training program for precision mouse phenotyping (2020) (0)
- Restless Legs Syndrome-associated intronic common-variant in Meis 1 alters enhancer function in the developing telencephalon Supplemental Material (2014) (0)
- High-throughput phenotypic assessment of cardiac physiology in four commonly used inbred mouse strains (2014) (0)
- Correction to: The International Mouse Phenotyping Consortium (IMPC): a functional catalogue of the mammalian genome that informs conservation (2019) (0)
- Animal welfare (2022) (0)
- Virtual expression patterns as simulated in silico by the proposed gene regulatory network. (2012) (0)
- Acute and long-term exercise adaptation of adipose tissue and skeletal muscle in humans: a matched transcriptomics approach after 8-week training-intervention (2023) (0)
- Abstract 298: Microfibrillar Protein 4 is an Integrin avß3/5 Ligand Involved in Vascular Remodeling (2013) (0)
- A rationale for considering heart/brain axis control in neuropsychiatric disease. (2022) (0)
- Compartmentalised expression of in epithelial somites is required for the formation of intervertebral joints-6 (2011) (0)
- P369 EXTRAHEPATIC MANIFESTATIONS OF ATP-BINDING CASSETTE TRANSPORTER B4 (ABCB4) DEFICIENCY DETECTED IN A SYSTEMATIC PHENOMICS PLATFORM (2014) (0)
- Mitogenic activity of the metabolically relevant hepatokine FGF21 in human carcinoma cells. (2016) (0)
- Role of free fatty acid signaling in islet function (2018) (0)
- Streptozotocin-induced β-cell damage, high fat diet, and metformin administration regulate Hes3 expression in the adult mouse brain (2018) (0)
- obesogenic exposure induces sex-specific programming of disease susceptibilities in adult mouse offspring (2013) (0)
- Aey17, a new small–eye phenotype caused by a mutation in Fgf10 (2004) (0)
- Identification of a New Mouse Mutation with Abnormalities of the Eye, AEY12 (2002) (0)
- Titan mice are a unique bred mammalian model to study obesity and aspects of metabolic syndrome (2020) (0)
- Emphysema susceptibility is modulated by the epigenetic regulator HMGN5 (2016) (0)
- Erratum to: New mouse models for metabolic bone diseases generated by genome-wide ENU mutagenesis (2014) (0)
- D2.3: Report on Stakeholder Meeting INFRAFRONTIER / IMPC Stakeholder Meeting: Advancing Personalised Medicine with Animal Models (2018) (0)
- SP045DETAILED MORPHOLOGICAL ANALYSES OF A NOVEL MOUSE MODEL OF SITE-SPECIFIC GLOMERULAR THROMBOTIC MICROANGIOPATHY (2015) (0)
- Splice‐site mutation in the Bmpr1b gene of the mouse causes optic nerve head dysgenesis and retinal gliosis (2016) (0)
- Contents Vol. 104, 2004 (2004) (0)
- Metabolic phenotyping of an overweight mouse line originated from ethyl-nitroso-urea (ENU) mutagenesis (2006) (0)
- LSC - 2017 - The role of the epigenetic regulator HMGN5 in COPD resulting from chronic lung injury (2017) (0)
- miRNA signatures in maternal whole blood cells of women with gestational diabetes. (2016) (0)
- FRI0059 Cardiac, pulmonary and periodontal disease as comorbidities in tnf-driven models of chronic polyarthritis (2017) (0)
- Author response for "Diabetes type 2 risk gene Dusp8 is associated with altered sucrose reward behavior in mice and humans" (2020) (0)
- The eye screen of the German Mouse Clinic (GMC) - New genetic insights into eye development and ocular disorders (2013) (0)
- Novel mouse phenotypes identified in the eye screen of the German Mouse Clinic (2015) (0)
- The plasma lipidomic signature of Abcb4–/– mice with secondary biliary fibrosis (2010) (0)
- Mutation in the Ercc2 gene of the mouse causes cataracts (2015) (0)
- Molecular and functional characterization of Aga2 — A mouse model for osteogenesis imperfecta (2009) (0)
- Chromatin dynamics via HMGN5 regulates COPD susceptibility (2020) (0)
- The negative adipogenesis regulator DLK1 is transcriptionally regulated by TIS7 (IFRD1) and translationally by its orthologue SKMc15 (IFRD2) (2019) (0)
- Mutation in the Crybb1 gene encoding beta-B1-crystallin leads to recessive cataracts in the mouse (2017) (0)
- Single housing reduces lung hemorrhages in male mice with tissue factor disulfide mutation and protects them from lethality (2013) (0)
- 417 Alum-free thermosensitive hydrogel as subcutaneous matrix for immunomodulators and allergens during specific immunotherapy (2016) (0)
- MS490 LARGE-SCALE PHENOTYPING OF EMP3-KNOCKOUT MICE AT THE GERMAN MOUSE CLINIC REVEALS A SPECIFIC ROLE OF THE GENE IN IMMUNITY (2010) (0)
- Objective hearing threshold identification from auditory brainstem response measurements using supervised and self-supervised approaches (2021) (0)
- Murine tissue factor disulfide mutation causes a bleeding phenotype with sex specific organ pathology and lethality. (2019) (0)
- Selection of housekeeping genes for gene expression 1 normalization in chicken embryo fibroblasts infected with 2 Newcastle disease virus 3 (2014) (0)
- SrGAP3/MEGAP knockout mice express schizophrenia-related endophenotypes (2011) (0)
- Correction: From Dynamic Expression Patterns to Boundary Formation in the Presomitic Mesoderm (2019) (0)
- Impaired glucose tolerance in newborn piglets exposed to mild hyperglycaemia in utero (2017) (0)
- P370 CHOLESTATIC Abcb4-DEFICIENT MICE REVEAL DEPRESSION/ANXIETY-LIKE BEHAVIOR (2014) (0)
- Deficiency in the expression of Vps13C is associated with altered retinal and lens development in mice (2017) (0)
- TIS7 and SKMc15 Regulate Adipocyte Differentiation and Intestinal Lipid Absorption (2019) (0)
- Differences in lung function among mouse inbred strains are genetically determined. (2004) (0)
- The effect of differentiation and TGFβ on mitochondrial respiration and mitochondrial enzyme abundance in cultured primary human skeletal muscle cells (2018) (0)
- Aqp5--/-- mice exhibit reduced maximal O2 consumption under cold exposure, normal pulmonary gas exchange, and impaired formation of brown adipose tissue. (2022) (0)
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