Martin Rodbell
#2,519
Most Influential Person Now
American biochemist
Martin Rodbell's AcademicInfluence.com Rankings
Martin Rodbellbiology Degrees
Biology
#123
World Rank
#226
Historical Rank
#74
USA Rank
Biochemistry
#73
World Rank
#93
Historical Rank
#45
USA Rank
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Biology
Martin Rodbell's Degrees
- PhD Biochemistry University of Washington
- Bachelors Chemistry University of Washington
Why Is Martin Rodbell Influential?
(Suggest an Edit or Addition)According to Wikipedia, Martin Rodbell was an American biochemist and molecular endocrinologist who is best known for his discovery of G-proteins. He shared the 1994 Nobel Prize in Physiology or Medicine with Alfred G. Gilman for "their discovery of G-proteins and the role of these proteins in signal transduction in cells."
Martin Rodbell's Published Works
Published Works
- METABOLISM OF ISOLATED FAT CELLS. I. EFFECTS OF HORMONES ON GLUCOSE METABOLISM AND LIPOLYSIS. (1964) (3869)
- A highly sensitive adenylate cyclase assay. (1974) (3714)
- The role of hormone receptors and GTP-regulatory proteins in membrane transduction (1980) (1575)
- The glucagon-sensitive adenyl cyclase system in plasma membranes of rat liver. V. An obligatory role of guanylnucleotides in glucagon action. (1971) (651)
- The glucagon-sensitive adenyl cyclase system in plasma membranes of rat liver. IV. Effects of guanylnucleotides on binding of 125I-glucagon. (1971) (524)
- The metabolism of isolated fat cells (1965) (511)
- The glucagon-sensitive adenyl cyclase system in plasma membranes of rat liver. I. Properties. (1971) (367)
- The glucagon-sensitive adenyl cyclase system in plasma membranes of rat liver. 3. Binding of glucagon: method of assay and specificity. (1971) (362)
- Adenyl cyclase in fat cells. 1. Properties and the effects of adrenocorticotropin and fluoride. (1969) (336)
- Advances in second messenger and phosphoprotein research (1988) (330)
- Adenyl cyclase in fat cells. II. Hormone receptors. (1969) (277)
- Metabolism of isolated fat cells. II. The similar effects of phospholipase C (Clostridium perfringens alpha toxin) and of insulin on glucose and amino acid metabolism. (1966) (222)
- Adenosine analogs inhibit adipocyte adenylate cyclase by a GTP-dependent process: basis for actions of adenosine and methylxanthines on cyclic AMP production and lipolysis. (1978) (212)
- Metabolism of isolated fat cells. V. Preparation of "ghosts" and their properties; adenyl cyclase and other enzymes. (1967) (212)
- LOCALIZATION OF LIPOPROTEIN LIPASE IN FAT CELLS OF RAT ADIPOSE TISSUE. (1964) (185)
- Evidence for interdependent action of glucagon and nucleotides on the hepatic adenylate cyclase system. (1974) (174)
- The glucagon-sensitive adenyl cyclase system in plasma membranes of rat liver. VI. Evidence for a role of membrane lipids. (1971) (174)
- The glucagon-sensitive adenyl cyclase system in plasma membranes of rat liver. II. Comparison between glucagon- and fluoride-stimulated activities. (1971) (170)
- 5'-Guanylylimidodiphosphate, a potent activator of adenylate cyclase systems in eukaryotic cells. (1974) (164)
- Metabolism of isolated fat cells. 3. The similar inhibitory action of phospholipase C (Clostridium perfringens alpha toxin) and of insulin on lipolysis stimulated by lipolytic hormones and theophylline. (1966) (159)
- Activation of adenylate cyclase in hepatic membranes involves interactions of the catalytic unit with multimeric complexes of regulatory proteins. (1979) (149)
- A persistent active state of the adenylate cyclase system produced by the combined actions of isoproterenol and guanylyl imidodiphosphate in frog erythrocyte membranes. (1975) (148)
- The role of acidic phospholipids in glucagon action on rat liver adenylate cyclase. (1973) (143)
- Stimulatory and inhibitory effects of guanyl nucleotides on fat cell adenylate cyclase. (1973) (140)
- Glucagon-Sensitive Adenyl Cylase in Plasma Membrane of Hepatic Parenchymal Cells (1969) (134)
- Adenyl cyclase in fat cells. 3. Stimulation by secretin and the effects of trypsin on the receptors for lipolytic hormones. (1969) (133)
- Adenosine receptor-mediated inhibition of rat cerebral cortical adenylate cyclase by a GTP-dependent process. (1980) (131)
- The fat cell adenylate cyclase system. Characterization and manipulation of its bimodal regulation by GTP. (1979) (128)
- Role of adenine and guanine nucleotides in the activity and response of adenylate cyclase systems to hormones: evidence for multisite transition states. (1975) (127)
- The hepatic adenylate cyclase system. I. Evidence for transition states and structural requirements for guanine nucloetide activiation. (1975) (115)
- MODULATION OF LIPOLYSIS IN ADIPOSE TISSUE BY FATTY ACID CONCENTRATION IN FAT CELL (1965) (110)
- ADP is a potent inhibitor of human platelet plasma membrane adenylate cyclase (1979) (108)
- The reaction of glucagon with its receptor: evidence for discrete regions of activity and binding in the glucagon molecule. (1971) (106)
- Evidence for distinct guanine nucleotide sites in the regulation of the glucagon receptor and of adenylate cyclase activity. (1977) (104)
- Programmable Messengers: A New Theory of Hormone Action (1985) (104)
- Structure-function relations in glucagon. Properties of highly purified Des-his1-, monoiodo-, and [Des-Asn28,Thr29](homoserine lactone27)-glucagon (1975) (100)
- Enzymatic formation of monopalmitoleyl- and monopalmitoyllecithin (lysolecithins). (1954) (99)
- Signal transduction: evolution of an idea. (1995) (95)
- GTP stimulates and inhibits adenylate cyclase in fat cell membranes through distinct regulatory processes. (1977) (94)
- The glucagon-sensitive adenylate cyclase system in plasma membranes of rat liver. VII. Hormonal stimulation: reversibility and dependence on concentration of free hormone. (1972) (93)
- The metabolism of isolated fat cells. IV. Regulation of release of protein by lipolytic hormones and insulin. (1966) (91)
- The role of the guanine nucleotide exchange reaction in the regulation of the beta-adrenergic receptor and in the actions of catecholamines and cholera toxin on adenylate cyclase in turkey erythrocyte membranes. (1980) (90)
- On the mechanism of activation of fat cell adenylate cyclase by guanine nucleotides. An explanation for the biphasic inhibitory and stimulatory effects of the nucleotides and the role of hormones. (1975) (85)
- Inactivation of glucagon by plasma membranes of rat liver. (1972) (85)
- METABOLISM OF CHYLOMICRONS AND TRIGLYCERIDE EMULSIONS BY PERFUSED RAT ADIPOSE TISSUE. (1965) (81)
- Solubilization and separation of the glucagon receptor and adenylate cyclase in guanine nucleotide-sensitive states. (1977) (75)
- Metabolism of isolated fat cells. VI. The effects of insulin, lipolytic hormones, and theophylline on glucose transport and metabolism in "ghosts". (1967) (67)
- N-terminal amino acid and lipid composition of lipoproteins from chyle and plasma. (1958) (67)
- Receptor-mediated stimulation and inhibition of adenylate cyclases: the fat cell as a model system. (1981) (65)
- The role of GTP-binding proteins in signal transduction: from the sublimely simple to the conceptually complex. (1992) (64)
- Effects of GTP on binding of (3H) glucagon to receptors in rat hepatic plasma membranes. (1977) (63)
- Characteristics of the guanine nucleotide regulatory component of adenylate cyclase in human erythrocyte membranes. (1980) (60)
- The nature of the proteins associated with dog ano human chylomicrons. (1959) (60)
- Multiple inhibitory and activating effects of nucleotides and magnesium on adrenal adenylate cyclase. (1975) (57)
- Effects of phospholipase A2 and filipin on the activation of adenylate cyclase. (1979) (55)
- Inhibition by fluoride ion of hormonal activation of fat cell adenylate cyclase. (1973) (54)
- Evidence for specific binding sites for guanine nucleotides in adipocyte and hepatocyte plasma membranes. A difference in fate of GTP and guanosine 5'-(beta, gamma-imino) triphosphate. (1975) (54)
- The hepatic adenylate cyclase system. II. Substrate binding and utilization and the effects of magnesium ion and pH. (1975) (53)
- The removal and metabolism of chylomicrons by adipose tissue in vitro. (1960) (50)
- Pertussis toxin induces structural changes in G alpha proteins independently of ADP-ribosylation. (1989) (50)
- Glucagon1-6 binds to the glucagon receptor and activates hepatic adenylate cyclase. (1979) (50)
- Isoproterenol stimulates shift of G proteins from plasma membrane to pinocytotic vesicles in rat adipocytes: a possible means of signal dissemination. (1990) (49)
- The complex regulation of receptor-coupled G-proteins. (1997) (48)
- The disaggregation theory of signal transduction revisited: further evidence that G proteins are multimeric and disaggregate to monomers when activated. (1993) (48)
- Preparation of isolated fat cells and fat cell "ghosts"; methods for assaying adenylate cyclase activity and levels of cyclic AMP. (1974) (46)
- The hepatic adenylate cyclase system. III. A mathematical model for the steady state kinetics of catalysis and nucleotide regulation. (1975) (45)
- The actions of insulin and catabolic hormones on the plasma membrane of the fat cells. (1968) (44)
- Octyl glucoside extracts GTP-binding regulatory proteins from rat brain "synaptoneurosomes" as large, polydisperse structures devoid of beta gamma complexes and sensitive to disaggregation by guanine nucleotides. (1990) (44)
- Metabolism of chylomicron proteins in the dog. (1959) (39)
- Inhibition and activation of fat cell adenylate cyclase by GTP is mediated by structures of different size. (1980) (37)
- Structure of the turkey erythrocyte adenylate cyclase system. (1981) (36)
- Heterotrimeric G proteins in synaptoneurosome membranes are crosslinked by p-phenylenedimaleimide, yielding structures comparable in size to crosslinked tubulin and F-actin. (1992) (35)
- The actions of hormones on the adenyl cyclase system. (1970) (35)
- REMOVAL AND METABOLISM OF TRIGLYCERIDES BY PERFUSED LIVER. (1964) (34)
- Effects of iodination of tyrosyl residues on the binding and action of glucagon at its receptor. (1976) (32)
- Glucagon induces disaggregation of polymer-like structures of the alpha subunit of the stimulatory G protein in liver membranes. (1991) (31)
- Cholera toxin modifies diverse GTP-modulated regulatory proteins. (1981) (30)
- Activation of hepatic adenylate cyclase by guanyl nucleotides. Modeling of the transient kinetics suggests an "excited" state of GTPase is a control component of the system. (1977) (30)
- Nobel Lecture. Signal transduction: evolution of an idea. (1995) (30)
- Adenyl Cyclase in Fat Cells THE EFFECTS OF ADRENOCORTICOTROPIN AND FLUORIDE (2002) (29)
- The role of adenine and guanine nucleotides in the activity and response of adenylate cyclase systems to hormones: evidence for multi-site transition states. (1974) (27)
- A reassessment of structure-function relationships in glucagon. Glucagon1-21 is a full agonist. (1978) (27)
- Proposed mechanism of insulin-resistant glucose transport in the isolated guinea pig adipocyte. Small intracellular pool of glucose transporters. (1983) (26)
- The Actions of Glucagon at Its Receptor: Regulation of Adenylate Cyclase (1983) (26)
- Simple model for hormone-activated adenylate cyclase systems. (1976) (24)
- Lecitin synthesis in liver. (1955) (24)
- Adenylate cyclase in polyacrylamide gel electrophoresis: solubilized but active. (1978) (24)
- The metabolism of isolated fat cells. 8. Amino acid transport in ghosts. (1969) (24)
- The characteristics of lubrol-solubilized adenylate cyclase from rat liver plasma membranes. (1978) (24)
- The structure of adenylate cyclase systems. (1981) (22)
- Independent mechanisms of adenosine activation and inhibition of the turkey erythrocyte adenylate cyclase system. (1980) (22)
- Solubilization and conversion of hepatic adenylate cyclase to a form requiring MnATP as substrate. (1979) (20)
- The metabolism of isolated fat cells. VII. Sodium-linked, energy-dependent, and ouabain-sensitive potassium accumulation in ghosts. (1969) (18)
- Regulation of hepatic adenylate cyclase by glucagon, GTP, divalent cations, and adenosine. (1976) (17)
- GTPases in Biology II (1993) (17)
- Semisynthetic glucagon derivatives for structure-function studies. (1976) (17)
- Preparation of 2-thioltryptophan-glucagon and (tryptophan-S-glucagon)2. Differences in binding to the glucagon receptor in the hepatic adenylate cyclase system. (1980) (15)
- Microsomal and cytosolic fractions of guinea pig hepatocytes contain 100-kilodalton GTP-binding proteins reactive with antisera against alpha subunits of stimulatory and inhibitory heterotrimeric GTP-binding proteins. (1990) (15)
- Letter: Insulin activity: the solid matrix. (1973) (14)
- Nobel Banquet 'Speech' (1994) (14)
- Hydroxybenzylpindolol and hydroxybenzylpropranolol: partial beta adrenergic agonists of adenylate cyclase in the rat adipocyte. (1976) (14)
- Some aspects of the metabolism of lecithin and its derivatives in liver. (1955) (14)
- [Properties of the adenyl cyclase systems in liver and adipose cells: the mode of action of hormones]. (1970) (13)
- Reversible activation of hepatic adenylate cyclase by guanyl-5'-yl-(alpha,beta-methylene)diphosphonate and guanyl-5'-yl imidodiphosphate. (1977) (13)
- CELL SURFACE RECEPTOR SITES (1972) (13)
- Selective effects of organic mercurials on the GTP-regulatory proteins of adenylate cyclase systems. (1980) (13)
- Structure-function relationships in glucagon: properties of highly purified des-His-1-, monoiodo-, and (des-Asn-28, Thr-29)(homoserine lactone-27)-glucagon. (1975) (12)
- Signal Transduction: Evolution of an Idea (Nobel Lecture) (1995) (12)
- In vitro assays of adenyl cyclase. (1971) (9)
- The problem of identifying the glucagon receptor. (1973) (9)
- Characteristics of glucagon action on the hepatic adenylate cyclase system. (1971) (9)
- Photoaffinity labeling of the glucagon receptor with a new glucagon analog. (1984) (8)
- Structure-function problems with the adenylate cyclase system. (1984) (8)
- G proteins: out of the cytoskeletal closet. (1996) (7)
- Carbachol-activated muscarinic (M1 and M3) receptors transfected into Chinese hamster ovary cells inhibit trafficking of endosomes. (1991) (7)
- Role of GTP‐binding proteins in hormone and drug action: Adenylate cyclase and other transduction processes (1987) (7)
- Preparation and properties of glucagon analogs prepared by semi-synthesis from CNBr-glucagon. (1980) (6)
- Properties of amidinated glucagons. (2005) (6)
- Activation of a guanosine triphosphate-specific protein kinase by adenosine 3':5'-monophosphate-dependent protein kinase in rat cells of the rat. (1973) (6)
- GTP-REGULATORY PROTEINS ARE INTRACELLULAR MESSENGERS: A MODEL FOR HORMONE ACTION (1985) (6)
- On the Sulphate Metabolism in the Sulphocerebrosides of the Brain. (1955) (5)
- The fat cell in mid-term: its past and future. (1970) (5)
- The Complex Structure and Regulation of Adenylate Cyclase (1983) (5)
- The coupling of hormone receptors and adenylate cyclase. (1977) (4)
- Bioinformatics: an emerging means of assessing environmental health. (1994) (4)
- G-Proteins Have Properties of Multimeric Proteins: An Explanation for the Role of GTPases in their Dynamic Behavior (1993) (4)
- Synthesis of Phospho-Peptides. O-Phospho-DL-Seryl-Glycine. (1955) (4)
- Insulin Activity: The Solid Matrix (1973) (3)
- Adenylate cyclase: actions and interactions of regulatory ligands (1977) (3)
- The Hepatic Adenylate Cyclase System (2002) (2)
- Signal Transduction in Biological Membranes (1985) (2)
- 5 – G Proteins May Exist as Polymeric Proteins: A Basis for the Disaggregation Theory of Hormone Action (1991) (1)
- Molecular mechanisms of hormone receptors. (1973) (1)
- The beginnings of an endocrinologist. (1991) (1)
- The complex structure and function of G-proteins in cellular communication. (1995) (1)
- Editorial: Bioinformatics: An Emerging Means of Assessing Environmental Health (1994) (1)
- Farewell to Somerset, Hello Chapel Hill (1985) (0)
- Letter from Martin Rodbell to Leon M. Lederman (1995) (0)
- Signal Transduction: A Twenty Year History of G-Proteins (1990) (0)
- Observations on Biosynthesis of Lecithins. (1955) (0)
- Founding Editor Editor-in-chief Regional Editors Editorial Board Springer International Contents Abe, Sa: Meiosis of Primary Spermatocytes and Early Sper- Miogenesis in the Resultant Spermatids in Newt, Cynops Pyrrhogaster in Vitro 65 Heterogeneity of Inter- Mediate Filament Expression in Vascular S (0)
- The Final Farewell or The Last Ode from Building 6 (1985) (0)
- The Role of GTP in the Coupling of Hormone Receptors and Adenylate Cyclase (1979) (0)
- Peptide Hormone Action and Membrane Receptors. (1973) (0)
- The actions of hormones on adenylate cyclase systems. (1978) (0)
- Ninth miles international symposium (2005) (0)
- [5] Cross-linking of synaptoneurosome G proteins (1996) (0)
- Purification and Chemical Properties of Enterokinase. (1955) (0)
- To My Friends: Thoughts from 'On High' (1994) (0)
- [Entry from] Desk Private: Appointments - Memoranda - Reminders - Diary (1939) (0)
- Proceedings of the International Conference on Cyclic Nucleotides, Calcium and Protein Phosphorylation (6th) Held in Bethesda, Maryland on September 2-7, 1986. Advances in Second Messenger and Phosphorprotein Research. Volume 21A. Abstracts Volume (1988) (0)
- Martin Rodbell Localization of Lipoprotein Lipase in Fat Cells of Rat Adipose Tissue (2003) (0)
- Martin Rodbell PROTEIN BY LIPOLYTIC HORMONES AND INSULIN The Metabolism of Isolated Fat Cells : IV . REGULATION OF RELEASE OF (2003) (0)
- Thoughts on the Regulation of Adenylyl Cyclase Systems by Hormone-Sensitive G-Proteins: A Tribute to Albert E. Renold (1997) (0)
- Letter from Martin Rodbell to Anil Joshi (1973) (0)
- The G lucagon-sensitive Adenyl Cyclase System in Plasma Membranes of Rat Liver (1999) (0)
- Gairdner Lecture: Introduction (1984) (0)
- III. A MATHEMATICAL MODEL FOR THE STEADY STATE KINETICS OF CATALYSIS AND NUCLEO- TIDE REGULATION (1975) (0)
- Letter from Martin Rodbell to Joseph J. Hoet (1995) (0)
- Binding of glucagon to its hepatic receptor: differences between native and iodinated glucagon (1977) (0)
- Letter from Martin Rodbell to Peter F. Hall (1979) (0)
- Letter from Martin Rodbell to Andre DeLean (1980) (0)
- Structure-function relations of the thyrotropin receptor - discussion (1982) (0)
- Structure-function relationships in adenylate cyclase systems. (1982) (0)
- A model for hormonal activation of adenylate cyclase (1974) (0)
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