Martine Roussel

Q: What Schools Are Affiliated With Martine Roussel

Martine Roussel is affiliated with the following schools: Aalborg University, University of Kentucky, Université Paris Cité, University of Tennessee Health Science Center, Duke University

Martine Roussel's AcademicInfluence.com Rankings

Martine Roussel

Biology

#7199

World Rank

#10081

Historical Rank

Molecular Biology

#805

World Rank

#825

Historical Rank

biology Degrees

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Biology

Martine Roussel's Degrees

PhD Molecular Biology Université Paris Cité

Why Is Martine Roussel Influential?

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According to Wikipedia, Martine F. Roussel is a molecular oncologist in the United States. She is a member of the National Academy of Sciences. Roussel works at the St. Jude Children's Research Hospital in Memphis, Tennessee.

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Martine Roussel's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization. (1998) (2175)
Tumor Suppression at the Mouse INK4a Locus Mediated by the Alternative Reading Frame Product p19 ARF (1997) (1727)
The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF 1 (1985) (1371)
Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization. (1998) (1338)
The p21Cip1 and p27Kip1 CDK ‘inhibitors’ are essential activators of cyclin D‐dependent kinases in murine fibroblasts (1999) (1235)
Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts. (1993) (1107)
Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle (1991) (1102)
Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2. (1998) (1010)
Nucleolar Arf sequesters Mdm2 and activates p53 (1999) (1000)
Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis. (1999) (859)
Identification and properties of an atypical catalytic subunit (p34PSK-J3/cdk4) for mammalian D type G1 cyclins (1992) (853)
Subgroup-specific structural variation across 1,000 medulloblastoma genomes (2012) (760)
Novel mutations target distinct subgroups of medulloblastoma (2012) (746)
Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6 (1995) (706)
E1A signaling to p53 involves the p19(ARF) tumor suppressor. (1998) (685)
Subtypes of medulloblastoma have distinct developmental origins (2010) (581)
Expression of the p16INK4a tumor suppressor versus other INK4 family members during mouse development and aging (1997) (553)
Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1). (1998) (538)
A variant Ewing's sarcoma translocation (7;22) fuses the EWS gene to the ETS gene ETV1. (1995) (483)
p53-independent functions of the p19(ARF) tumor suppressor. (2000) (402)
Three new types of viral oncogene of cellular origin specific for haematopoietic cell transformation (1979) (367)
DNA-binding and transcriptional activation properties of the EWS-FLI-1 fusion protein resulting from the t(11;22) translocation in Ewing sarcoma (1994) (366)
The INK4 family of cell cycle inhibitors in cancer (1999) (334)
Nucleolar Arf tumor suppressor inhibits ribosomal RNA processing. (2003) (300)
Cooperative Signals Governing ARF-Mdm2 Interaction and Nucleolar Localization of the Complex (2000) (297)
Transforming potential of the c-fms proto-oncogene (CSF-1 receptor) (1987) (293)
The miR-17∼92 cluster collaborates with the Sonic Hedgehog pathway in medulloblastoma (2009) (289)
Genomic organization, chromosomal localization, and independent expression of human cyclin D genes. (1992) (277)
A mouse model of the most aggressive subgroup of human medulloblastoma. (2012) (273)
DNA synthesis induced by some but not all growth factors requires Src family protein tyrosine kinases (1995) (252)
E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification. (2009) (245)
N-terminal polyubiquitination and degradation of the Arf tumor suppressor. (2004) (240)
Loss of p53 Induces Changes in the Behavior of Subventricular Zone Cells: Implication for the Genesis of Glial Tumors (2006) (232)
Apoptosis Triggered by Myc-Induced Suppression of Bcl-XL or Bcl-2 Is Bypassed during Lymphomagenesis (2001) (226)
Somatic CRISPR/Cas9-mediated tumour suppressor disruption enables versatile brain tumour modelling (2015) (225)
Stat5a/b contribute to interleukin 7-induced B-cell precursor expansion, but abl- and bcr/abl-induced transformation are independent of stat5. (2000) (221)
A point mutation in the extracellular domain of the human CSF-1 receptor (c-fms proto-oncogene product) activates its transforming potential (1988) (213)
A molecular fingerprint for medulloblastoma. (2003) (212)
Medulloblastoma Genotype Dictates Blood Brain Barrier Phenotype. (2016) (206)
Arf gene loss enhances oncogenicity and limits imatinib response in mouse models of Bcr-Abl-induced acute lymphoblastic leukemia. (2006) (203)
Synthesis of membrane-bound colony-stimulating factor 1 (CSF-1) and downmodulation of CSF-1 receptors in NIH 3T3 cells transformed by cotransfection of the human CSF-1 and c-fms (CSF-1 receptor) genes (1987) (200)
Ligand and protein kinase C downmodulate the colony-stimulating factor 1 receptor by independent mechanisms (1989) (199)
TNF Counterbalances the Emergence of M2 Tumor Macrophages. (2015) (194)
Cerebellum development and medulloblastoma. (2011) (192)
Postnatal neuronal proliferation in mice lacking Ink4d and Kip1 inhibitors of cyclin-dependent kinases. (1999) (188)
Progressive hearing loss in mice lacking the cyclin-dependent kinase inhibitor Ink4d (2003) (185)
Bax Loss Impairs Myc-Induced Apoptosis and Circumvents the Selection of p53 Mutations during Myc-Mediated Lymphomagenesis (2001) (184)
Age-Dependent In Vivo Conversion of Mouse Cochlear Pillar and Deiters' Cells to Immature Hair Cells by Atoh1 Ectopic Expression (2012) (181)
Arf tumor suppressor promoter monitors latent oncogenic signals in vivo (2003) (175)
Development and cancer of the cerebellum (2011) (169)
The tumor suppressors Ink4c and p53 collaborate independently with Patched to suppress medulloblastoma formation. (2005) (164)
Molecular heterogeneity and CXorf67 alterations in posterior fossa group A (PFA) ependymomas (2018) (162)
Induction of ARF tumor suppressor gene expression and cell cycle arrest by transcription factor DMP1. (1999) (162)
Mitogenic signaling by colony-stimulating factor 1 and ras is suppressed by the ets-2 DNA-binding domain and restored by myc overexpression (1992) (162)
Post-transcriptional down-regulation of Atoh1/Math1 by bone morphogenic proteins suppresses medulloblastoma development. (2008) (158)
Tandem linkage of human CSF-1 receptor (c-fms) and PDGF receptor genes (1988) (150)
Expression of the human c-fms proto-oncogene product (colony-stimulating factor-1 receptor) on peripheral blood mononuclear cells and choriocarcinoma cell lines. (1986) (142)
Differing contribution of thiopurine methyltransferase to mercaptopurine versus thioguanine effects in human leukemic cells. (2001) (142)
INK4d-Deficient Mice Are Fertile Despite Testicular Atrophy (2000) (137)
The product of the c-fms proto-oncogene: a glycoprotein with associated tyrosine kinase activity. (1985) (135)
A unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8 (2004) (134)
Dual control of myc expression through a single DNA binding site targeted by ets family proteins and E2F-1. (1994) (132)
Expression of INK4 inhibitors of cyclin D-dependent kinases during mouse brain development. (1997) (128)
Rescue of defective mitogenic signaling by D-type cyclins. (1995) (127)
Role of MYC in Medulloblastoma. (2013) (126)
Silencing of the miR-17~92 cluster family inhibits medulloblastoma progression. (2013) (125)
Inhibition of cell proliferation by the Mad1 transcriptional repressor (1996) (124)
Intrinsic disorder mediates the diverse regulatory functions of the Cdk inhibitor p21 (2011) (121)
Pemetrexed and gemcitabine as combination therapy for the treatment of Group3 medulloblastoma. (2014) (121)
Cell surface expression of v-fms-coded glycoproteins is required for transformation (1984) (119)
Control of Spermatogenesis in Mice by the Cyclin D-Dependent Kinase Inhibitors p18Ink4c and p19Ink4d (2001) (117)
Disruption of the ARF transcriptional activator DMP1 facilitates cell immortalization, Ras transformation, and tumorigenesis. (2000) (117)
Autocrine CSF-1R activation promotes Src-dependent disruption of mammary epithelial architecture (2004) (115)
p53-Dependent and -independent functions of the Arf tumor suppressor. (2005) (113)
The distribution of endogenous chicken retrovirus sequences in the DNA of galliform birds does not coincide with avian phylogenetic relationships (1979) (113)
A rate limiting function of cdc25A for S phase entry inversely correlates with tyrosine dephosphorylation of Cdk2 (1999) (113)
The Oncogenic Potential of the Pax3-FKHR Fusion Protein Requires the Pax3 Homeodomain Recognition Helix but Not the Pax3 Paired-Box DNA Binding Domain (1999) (109)
Arf induces p53-dependent and -independent antiproliferative genes. (2003) (108)
Targeting Metabolic Reprogramming by Influenza Infection for Therapeutic Intervention. (2017) (106)
Histone deacetylase inhibitors activate INK4d gene through Sp1 site in its promoter (2004) (105)
Differential processing of colony-stimulating factor 1 precursors encoded by two human cDNAs (1988) (104)
A point mutation at tyrosine-809 in the human colony-stimulating factor 1 receptor impairs mitogenesis without abrogating tyrosine kinase activity, association with phosphatidylinositol 3-kinase, or induction of c-fos and junB genes. (1990) (104)
Myc-mediated proliferation and lymphomagenesis, but not apoptosis, are compromised by E2f1 loss. (2003) (102)
Cyclin-dependent kinase inhibitors in the development of the central nervous system. (2001) (101)
p19Ink4d and p21Cip1 Collaborate to Maintain the Postmitotic State of Auditory Hair Cells, Their Codeletion Leading to DNA Damage and p53-Mediated Apoptosis (2007) (99)
The MN1-TEL Fusion Protein, Encoded by the Translocation (12;22)(p13;q11) in Myeloid Leukemia, Is a Transcription Factor with Transforming Activity (2000) (97)
Differential effects of p19Arf and p16Ink4a loss on senescence of murine bone marrow-derived preB cells and macrophages (2001) (97)
Oncogenic Ras induces p19ARF and growth arrest in mouse embryo fibroblasts lacking p21Cip1 and p27Kip1 without activating cyclin D-dependent kinases. (2000) (96)
A signaling to p 53 involves the p 19 ARF tumor suppressor (1998) (96)
Monoclonal antibodies to the human CSF-1 receptor (c-fms proto-oncogene product) detect epitopes on normal mononuclear phagocytes and on human myeloid leukemic blast cells. (1989) (91)
Atoh1 inhibits neuronal differentiation and collaborates with Gli1 to generate medulloblastoma-initiating cells. (2010) (90)
Transforming activity of EWS/FLI is not strictly dependent upon DNA-binding activity (1999) (89)
The RING domain of Mdm2 can inhibit cell proliferation. (2002) (88)
D-type cyclins and their cyclin-dependent kinases: G1 phase integrators of the mitogenic response. (1994) (87)
Signaling by ABL oncogenes through cyclin D1. (1995) (82)
Hemangiosarcomas, medulloblastomas, and other tumors in Ink4c/p53-null mice. (2003) (79)
Genetic alterations in mouse medulloblastomas and generation of tumors de novo from primary cerebellar granule neuron precursors. (2007) (77)
Novel mammalian cyclins (CYL genes) expressed during G1. (1991) (75)
Single-Cell Transcriptomics in Medulloblastoma Reveals Tumor-Initiating Progenitors and Oncogenic Cascades during Tumorigenesis and Relapse. (2019) (74)
N-Myc and the cyclin-dependent kinase inhibitors p18Ink4c and p27Kip1 coordinately regulate cerebellar development. (2006) (74)
Cyclin D- and E-Dependent Kinases and the p57KIP2 Inhibitor: Cooperative Interactions In Vivo (1999) (73)
Transmembrane orientation of glycoproteins encoded by the v-fms oncogene (1985) (72)
Two Tumor Suppressors, p27Kip1 and Patched-1, Collaborate to Prevent Medulloblastoma (2009) (68)
WNT3 Inhibits Cerebellar Granule Neuron Progenitor Proliferation and Medulloblastoma Formation via MAPK Activation (2013) (67)
Stat3-Dependent Induction of p19INK4D by IL-10 Contributes to Inhibition of Macrophage Proliferation1 (2000) (65)
Multilineage hematopoietic disorders induced by transplantation of bone marrow cells expressing the v-fms oncogene (1987) (63)
Identification of Small Molecule Activators of BMP Signaling (2013) (63)
A potential role for Elf-1 in terminal transferase gene regulation (1996) (60)
The Interaction of Myc with Miz1 Defines Medulloblastoma Subgroup Identity. (2016) (60)
Expression of c-Myc in Response to Colony-stimulating Factor-1 Requires Mitogen-activated Protein Kinase Kinase-1* (1999) (59)
Whole-Body Physiologically Based Pharmacokinetic Model for Nutlin-3a in Mice after Intravenous and Oral Administration (2011) (58)
Inactivation of Ezh2 Upregulates Gfi1 and Drives Aggressive Myc-Driven Group 3 Medulloblastoma. (2017) (57)
Zeb1 controls neuron differentiation and germinal zone exit by a mesenchymal-epithelial-like transition (2016) (57)
CDK2 inhibitors as candidate therapeutics for cisplatin- and noise-induced hearing loss (2018) (56)
Glycogen synthase kinase-3 b regulates cyclin D1 proteolysis and subcellular localization (1998) (56)
Key effectors of signal transduction and G1 progression. (1998) (54)
Mouse NIH 3T3 cells expressing human colony-stimulating factor 1 (CSF-1) receptors overgrow in serum-free medium containing human CSF-1 as their only growth factor. (1989) (53)
Transfer and expression of the gene encoding a human myeloid membrane antigen (gp150). (1985) (53)
Colony‐stimulating factor‐1 receptor (c‐fms) (1988) (53)
Expression of p19INK4d, CDK4, CDK6 in glioblastoma multiforme. (2000) (52)
Regulation of cell cycle entry and G1 progression by CSF‐1 (1997) (50)
Epigenetic Drivers in Pediatric Medulloblastoma (2017) (49)
MYC competes with MiT/TFE in regulating lysosomal biogenesis and autophagy through an epigenetic rheostat (2019) (48)
Differential effects of p19(Arf) and p16(Ink4a) loss on senescence of murine bone marrow-derived preB cells and macrophages. (2001) (47)
N-myc coordinates retinal growth with eye size during mouse development. (2008) (46)
Features of macrophage differentiation induced by p19INK4d, a specific inhibitor of cyclin D-dependent kinases. (1997) (45)
Inhibition of colony-stimulating factor-1 activity by monoclonal antibodies to the human CSF-1 receptor. (1989) (45)
mTORC1-Mediated Inhibition of 4EBP1 Is Essential for Hedgehog Signaling-Driven Translation and Medulloblastoma. (2017) (45)
Miz1 is required to maintain autophagic flux (2013) (44)
Structural Dissection of a Gating Mechanism Preventing Misactivation of Ubiquitin by NEDD8’s E1 (2008) (44)
Complementation of growth factor receptor-dependent mitogenic signaling by a truncated type I phosphatidylinositol 4-phosphate 5-kinase (1997) (44)
Three new types of viral oncogenes in defective avian leukemia viruses. I. Specific nucleotide sequences of cellular origin correlate with specific transformation. (1980) (43)
Signal transduction by the macrophage-colony-stimulating factor receptor (CSF-1R) (1994) (42)
The critical role that STAT3 plays in glioma-initiating cells: STAT3 addiction in glioma (2018) (41)
Macrophage colony-stimulating factor, CSF-1, and its proto-oncogene-encoded receptor. (1988) (40)
The colony-stimulating factor 1 (CSF-1) receptor (c-fms proto-oncogene product) and its ligand (1988) (39)
The carboxy-terminal catalytic domain of the GTPase-activating protein inhibits nuclear signal transduction and morphological transformation mediated by the CSF-1 receptor. (1991) (39)
Roles of p53 and p27 Kip1 in the regulation of neurogenesis in the murine adult subventricular zone (2011) (38)
c-Myc-mediated Regulation of Telomerase Activity Is Disabled in Immortalized Cells* (2001) (38)
Cell surface antigen profiling of pediatric brain tumors: B7-H3 is consistently expressed and can be targeted via local or systemic CAR T-cell delivery. (2020) (38)
Transduction of human colony-stimulating factor-1 (CSF-1) receptor into interleukin-3-dependent mouse myeloid cells induces both CSF-1-dependent and factor-independent growth (1989) (38)
The CDK Inhibitor p18Ink4c is a Tumor Suppressor in Medulloblastoma (2006) (37)
Characterization of the oncogene (erb) of avian erythroblastosis virus and its cellular progenitor (1981) (36)
Cloning and chromosomal localization of the gene encoding human cyclin D-binding Myb-like protein (hDMP1). (1999) (36)
Molecular cloning, expression, and chromosomal localization of the gene encoding a human myeloid membrane antigen (gp150). (1986) (36)
E2f1–3 Are Critical for Myeloid Development* (2010) (35)
Novel MYC-driven medulloblastoma models from multiple embryonic cerebellar cells (2017) (35)
Inhibition of Hsp90 via 17-DMAG induces apoptosis in a p53-dependent manner to prevent medulloblastoma (2009) (35)
Synthesis, post-translational processing, and autocrine transforming activity of a carboxylterminal truncated form of colony stimulating factor-1. (1987) (35)
The chimeric E2A-HLF transcription factor abrogates p53-induced apoptosis in myeloid leukemia cells. (1998) (34)
Introduction of a human colony stimulating factor-1 gene into a mouse macrophage cell line induces CSF-1 independence but not tumorigenicity. (1988) (32)
Monoclonal antibodies to mammalian D-type G1 cyclins. (1994) (32)
Cloning and expression of murine interleukin-1 receptor antagonist in macrophages stimulated by colony-stimulating factor 1. (1991) (32)
Cloning and expression of the murine Elf-1 cDNA. (1996) (32)
Ligand-induced phosphorylation of the colony-stimulating factor 1 receptor can occur through an intermolecular reaction that triggers receptor down modulation (1990) (32)
Patient-derived orthotopic xenografts of pediatric brain tumors: a St. Jude resource (2020) (31)
Regulation of CYL/cyclin D genes by colony-stimulating factor 1. (1992) (31)
Cytokines and sodium induce protein kinase A-dependent cell-surface Na,K-ATPase recruitment via dissociation of NF-kappaB/IkappaB/protein kinase A catalytic subunit complex in collecting duct principal cells. (2005) (30)
Random mutagenesis of CSF‐1 receptor (FMS) reveals multiple sites for activating mutations within the extracellular domain. (1992) (29)
Binding of carbon nanotube to BMP receptor 2 enhances cell differentiation and inhibits apoptosis via regulating bHLH transcription factors (2012) (28)
Role of the miR-17∼92 cluster family in cerebellar and medulloblastoma development (2014) (28)
Transforming activities of human CSF-1 receptors with different point mutations at codon 301 in their extracellular domains. (1990) (28)
Monoclonal antibodies to the mouse p19(Arf) tumor suppressor protein. (2004) (28)
Phenyl-Glutarimides: Alternative Cereblon Binders for the Design of PROTACs. (2021) (28)
Upregulated heme biosynthesis, an exploitable vulnerability in MYCN-driven leukemogenesis. (2017) (27)
Casein kinase 1δ is an APC/C(Cdh1) substrate that regulates cerebellar granule cell neurogenesis. (2015) (26)
ABCG2 Transporter Expression Impacts Group 3 Medulloblastoma Response to Chemotherapy. (2015) (26)
From Delta to Omicron: analysing the SARS-CoV-2 epidemic in France using variant-specific screening tests (September 1 to December 18, 2021) (2022) (22)
Identification of Potent, Selective, and Orally Bioavailable Small-Molecule GSPT1/2 Degraders from a Focused Library of Cereblon Modulators (2021) (22)
Overexpression of mouse D-type cyclins accelerates G 1 phase in (2007) (22)
Colony-stimulating factor 1-mediated regulation of a chimeric c-fms/v-fms receptor containing the v-fms-encoded tyrosine kinase domain. (1988) (22)
Differential post-transcriptional regulation of two Ink4 proteins, p18Ink4c and p19Ink4d (2008) (22)
Features of Macrophage Differentiation Induced by p19INK4d, a Specific Inhibitor of Cyclin D–Dependent Kinases (1997) (20)
A Network of Transcription Factors Operates during Early Tooth Morphogenesis (2013) (20)
Ventromorphins: A New Class of Small Molecule Activators of the Canonical BMP Signaling Pathway. (2017) (19)
Rethinking brain tumors: the fourth Mouse Models of Human Cancers Consortium nervous system tumors workshop. (2008) (19)
Modeling pediatric medulloblastoma (2019) (19)
Small-molecule screen reveals synergy of cell cycle checkpoint kinase inhibitors with DNA-damaging chemotherapies in medulloblastoma (2021) (18)
Patient-derived models recapitulate heterogeneity of molecular signatures and drug response in pediatric high-grade glioma (2021) (17)
E1A signaling to p53 involves the p19 tumor suppressor (1998) (17)
Exploiting a water network to achieve enthalpy-driven, bromodomain-selective BET inhibitors. (2018) (17)
p53-independent functions of the p19 tumor suppressor (2000) (17)
Bromodomain-Selective BET Inhibitors Are Potent Antitumor Agents against MYC-Driven Pediatric Cancer (2020) (16)
Functional expression of the human receptor for colony-stimulating factor 1 (CSF-1) in hamster fibroblasts: CSF-1 stimulates Na+/H+ exchange and DNA-synthesis in the absence of phosphoinositide breakdown. (1990) (16)
Failure of human rhombic lip differentiation underlies medulloblastoma formation (2022) (16)
A CK1α Activator Penetrates the Brain and Shows Efficacy Against Drug-resistant Metastatic Medulloblastoma (2018) (16)
Mouse medulloblastoma driven by CRISPR activation of cellular Myc (2018) (15)
Production and characterization of human monoclonal antibodies against core protein p25 and transmembrane glycoprotein gp41 of HIV-1. (1990) (15)
Stat 5 a / b contribute to interleukin 7 – induced B-cell precursor expansion , but abl-and bcr / abl-induced transformation are independent of Stat 5 (2000) (14)
Myc and Loss of p53 Cooperate to Drive Formation of Choroid Plexus Carcinoma. (2019) (13)
Preclinical studies of 5-fluoro-2′-deoxycytidine and tetrahydrouridine in pediatric brain tumors (2015) (13)
Drugging the “Undruggable” MYCN Oncogenic Transcription Factor: Overcoming Previous Obstacles to Impact Childhood Cancers (2021) (13)
Antibody-induced mitogenicity mediated by a chimeric CD2-c-fms receptor (1990) (13)
Oncogenic Potential of the c-FMS Proto-Oncogene (CSF-1 Receptor) (2003) (13)
Cross-species epigenetics identifies a critical role for VAV1 in SHH subgroup medulloblastoma maintenance (2014) (13)
Generation of Atoh1-rtTA transgenic mice: a tool for inducible gene expression in hair cells of the inner ear (2014) (11)
CNS penetration and pharmacodynamics of the CHK1 inhibitor prexasertib in a mouse Group 3 medulloblastoma model. (2020) (10)
Dicer Is Required for Normal Cerebellar Development and to Restrain Medulloblastoma Formation (2015) (10)
Medulloblastoma: advances and challenges (2011) (10)
Medulloblastoma recurrence and metastatic spread are independent of colony-stimulating factor 1 receptor signaling and macrophage survival (2021) (9)
Regulation of cell growth and differentiation by the colony-stimulating factor 1 receptor. (1991) (9)
Faculty Opinions recommendation of Declining p53 function in the aging process: a possible mechanism for the increased tumor incidence in older populations. (2007) (9)
Exome sequencing analysis of murine medulloblastoma models identifies WDR11 as a potential tumor suppressor in Group 3 tumors. (2017) (9)
Preclinical Modeling of Image-Guided Craniospinal Irradiation for Very-High-Risk Medulloblastoma. (2019) (9)
Establishing a Preclinical Multidisciplinary Board for Brain Tumors (2018) (9)
Ink4c is dispensable for tumor suppression in Myc-induced B-cell lymphomagenesis (2007) (8)
The Chimeric E2A-HLF Transcription Factor Abrogates p53-Induced Apoptosis in Myeloid Leukemia Cells (1998) (8)
senescence of murine bone marrow-derived preB cells and macrophages (2001) (8)
Hemangiosarcomas , Medulloblastomas , and Other Tumors in Ink 4 c / p 53-null Mice 1 (2003) (7)
Women in cancer research (2019) (7)
A new genetically engineered mouse model of choroid plexus carcinoma. (2018) (7)
An ABC Transporter Drives Medulloblastoma Pathogenesis by Regulating Sonic Hedgehog Signaling (2020) (6)
Faculty Opinions recommendation of Oscillatory control of factors determining multipotency and fate in mouse neural progenitors. (2014) (6)
Development and validation of a sensitive LC MS/MS method for the measurement of the checkpoint kinase 1 inhibitor prexasertib and its application in a cerebral microdialysis study (2018) (6)
p53: regular or super? (2002) (5)
Ventromorphins: A New Class of Small Molecule Activators of the Canonical BMP Signaling Pathway. (2019) (5)
Can diphtheria toxin be used for gene therapy of human immunodeficiency virus infection? (1992) (5)
Embryonic Expression and Function of the Xenopus Ink4d Cyclin D-Dependent Kinase Inhibitor (2014) (4)
The miR-17 similar to 92 cluster collaborates with the Sonic Hedgehog pathway in medulloblastoma (2009) (4)
Preclinical Models of Craniospinal Irradiation for Medulloblastoma (2020) (4)
Control of G1 Progression by Mammalian D-Type Cyclins (1994) (4)
Signal-response coupling mediated by the transduced colony-stimulating factor-1 receptor and its oncogenic fms variants in naive cells. (1990) (4)
Faculty Opinions recommendation of Mammalian cochlear supporting cells can divide and trans-differentiate into hair cells. (2006) (4)
Primary cilia control translation and the cell cycle in medulloblastoma (2022) (4)
Requirements for transformation by the fms oncogene product (CSF-1 receptor). (1986) (3)
Exome sequencing analysis of murine medulloblastoma models identifies WDR11 as a potential tumor suppressor in Group 3 tumors (2017) (3)
The Chimeric E 2 A-HLF Transcription Factor Abrogates p 53-Induced Apoptosis in Myeloid Leukemia Cells (1998) (3)
RNAs viraux des cellules infectées par un oncornavirus: I. — Caractérisation des RNAs viraux associés à des particules cytoplasmiques (1977) (3)
Molecular Characterization of Medulloblastoma Mouse Models -On the Avenue to More Elaborate Preclinical Testing Strategies (2013) (3)
The RING Domain of Mdm 2 Can Inhibit Cell Proliferation 1 (2002) (3)
Faculty of 1000 evaluation for A luminal epithelial stem cell that is a cell of origin for prostate cancer. (2009) (3)
Global Hypoactivity and Apathy (2017) (2)
Structure of APPBP1-UBA3-Ubc12N26: a unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8 (2004) (2)
Combination of Ribociclib with BET-Bromodomain and PI3K/mTOR Inhibitors for Medulloblastoma Treatment In Vitro and In Vivo (2022) (2)
d Is an APC/C Cdh1 Substrate that Regulates Cerebellar Granule Cell Neurogenesis (2015) (2)
Thrombospondin-1 mimetics are promising novel therapeutics for MYC-associated medulloblastoma (2021) (2)
Arf Induces p 53-dependent and-independent Antiproliferative Genes 1 , 2 (2003) (2)
HIV-triggered killing of booby trapped cells prevents viral spread in an HIV-infected cell population. (1992) (2)
Supplemental Data E 2-RING Expansion of the NEDD 8 Cascade Confers Specificity to Cullin Modification (2009) (2)
Faculty Opinions recommendation of Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors. (2017) (2)
New concepts in organ site research on medulloblastoma: genetics and genomics. (2010) (2)
Characterization oftheOncogene (erb) ofAvian Erythroblastosis Virus andItsCellular Progenitor (1981) (1)
Abstract 3448: Subtypes of medulloblastoma have distinct developmental origins (2011) (1)
The Oncogenic Potential of the Pax3-FKHR Fusion Protein Requires the Pax3 Homeodomain Recognition Helix but Not the Pax3 Paired-Box DNA Binding Domain (1999) (1)
THER-30. COMBINATION TOCA 511 & 5-FC SIGNIFICANTLY EXTENDS SURVIVAL IN A MURINE ORTHOTOPIC MODEL OF INTRACEREBELLAR MEDULLOBLASTOMA (2019) (1)
Phenyl‐Glutarimides: Alternative Cereblon Binders for the Design of PROTACs (2021) (1)
Faculty Opinions recommendation of Negative regulation of neural stem/progenitor cell proliferation by the Pten tumor suppressor gene in vivo. (2002) (1)
AACR Calls on Congress to Take Immediate Action Against COVID-19 and Protect Patients with Cancer During the Pandemic. (2020) (1)
MyD88 and Stat3 signaling are fundamental to tumor associated macrophage function (162.34) (2012) (1)
[TP53 and RB tumor suppressor pathways collaborate in retinoblastoma genesis]. (2007) (1)
PDTM-19. TOCA 511 & TOCA FC: PRE-CLINICAL PROOF OF CONCEPT IN MEDULLOBLASTOMA (2017) (1)
Abstract 4522: Identification of small molecule agonists/activators of BMP-2, 4, 7 signaling (2011) (1)
Abstract 6144: St. Jude Pediatric Brain Tumor Portal: Cloud-based resource for patient-derived orthotopic xenograft (PDOX) models of pediatric high-grade glioma, ependymoma, and CNS embryonal tumors (2020) (1)
IMMU-14. IMPLICATIONS FOR T-CELL IMMUNOTHERAPY: CELL SURFACE ANTIGEN AND HLA class I EXPRESSION IN PEDIATRIC BRAIN TUMORS ARE HETEROGENOUS (2019) (1)
Patient-Derived Orthotopic Xenografts and Cell Lines from Pediatric High-Grade Glioma Recapitulate the Heterogeneity of Histopathology, Molecular Signatures, and Drug Response (2020) (1)
but abl- andbcr/abl-induced transformation are independent of Stat5 induced B-cell precursor expansion, - Stat5a/b contribute to interleukin 7 (2013) (1)
Avian leukaemia viruses and haematopoietic cell differentiation. (1980) (1)
[Origin of the transforming genes in avian acute leukemia retroviruses]. (1980) (0)
Mammalian G1 cyclins in growth control (1994) (0)
Abstract 2968: Interrogating the function of histone methyltransferases in MYC-driven medulloblastoma (2022) (0)
Macrophage Proliferation IL-10 Contributes to Inhibition of byINK 4 DStat 3-Dependent Induction of p 19 (2000) (0)
INSP-09. Using genetically engineered mouse models and patient-derived orthotopic xenografts to develop new therapies for pediatric brain tumors. (2022) (0)
Faculty Opinions recommendation of Shh signaling protects Atoh1 from degradation mediated by the E3 ubiquitin ligase Huwe1 in neural precursors. (2015) (0)
Faculty Opinions recommendation of Sustained regression of tumors upon MYC inactivation requires p53 or thrombospondin-1 to reverse the angiogenic switch. (2006) (0)
Faculty Opinions recommendation of E2F4 loss suppresses tumorigenesis in Rb mutant mice. (2003) (0)
In Vivo Interactions p57 KIP2 Inhibitor: Cooperative Cyclin D- and E-Dependent Kinases and the (2013) (0)
Faculty Opinions recommendation of SMARCB1 Loss Interacts with Neuronal Differentiation State to Block Maturation and Impact Cell Stability. (2020) (0)
Faculty Opinions recommendation of Inactivation of the p53 pathway in retinoblastoma. (2006) (0)
Genetic Interaction of the BCR-ABL Oncogene and the ARF Tumor Suppressor in Ph+ Lymphoid Leukemia. (2005) (0)
Note from the Reviews Section Editorial Board (2005) (0)
Transfer andExpression oftheGeneEncoding a HumanMyeloid MembraneAntigen (gp150) (1985) (0)
Colony‐stimulating factors and cell cycle progression (1992) (0)
Faculty Opinions recommendation of p53 binds to and is required for the repression of Arf tumor suppressor by HDAC and polycomb. (2011) (0)
CB-14GENOMIC APPROACHES TO IDENTIFY CODING AND NONCODING RNA TARGETS IN MEDULLOBLASTOMA. (2014) (0)
Faculty Opinions recommendation of Feedback circuit among INK4 tumor suppressors constrains human glioblastoma development. (2008) (0)
Faculty Opinions recommendation of Small-Molecule MYC Inhibitors Suppress Tumor Growth and Enhance Immunotherapy. (2020) (0)
Abstract 2977: Myc and Miz1 in medulloblastoma (2014) (0)
Detection and characterization of circulating endothelial cells in multiple myeloma versus monoclonal gammapathy of indeterminated signifiance. (2011) (0)
Faculty Opinions recommendation of Nras loss induces metastatic conversion of Rb1-deficient neuroendocrine thyroid tumor. (2006) (0)
EXTH-73. HETEROGENEITY IN CELL SURFACE ANTIGEN AND HLA CLASS I EXPRESSION IN PEDIATRIC BRAIN TUMORS AND ITS IMPACT ON T-CELL IMMUNOTHERAPY (2020) (0)
MycandLossofp53Cooperate toDriveFormation of Choroid Plexus Carcinoma (2019) (0)
IMMU-06. T-CELL IMMUNOTHERAPY FOR PEDIATRIC BRAIN TUMORS: DIVERSITY IN CELL SURFACE ANTIGEN AND HLA EXPRESSION NECESSITATES A MULTI-PRONGED APPROACH (2020) (0)
Faculty Opinions recommendation of Definition of genetic events directing the development of distinct types of brain tumors from postnatal neural stem/progenitor cells. (2012) (0)
Identification of genes involved in medulloblastoma formation (2006) (0)
Faculty Opinions recommendation of "Super p53" mice exhibit enhanced DNA damage response, are tumor resistant and age normally. (2002) (0)
Faculty Opinions recommendation of A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy. (2002) (0)
Abstract PR005: Targeting EP300 and CBP for therapeutic benefit in pediatric solid tumors (2022) (0)
Haploinsuffiency of ornithine decarboxylase or use of a-difluoromethylornithine compromises tumorigenesis in various mouse models of cancer (2003) (0)
MBRS-02. BET BROMODOMAIN PROTEIN-KINASE INHIBITOR COMBINATIONS FOR THE TREATMENT OF MEDULLOBLASTOMA (2020) (0)
Faculty Opinions recommendation of p19(ARF) is dispensable for oncogenic stress-induced p53-mediated apoptosis and tumor suppression in vivo. (2002) (0)
Abstract IA21: Pediatric medulloblastoma: Drug screens and preclinical studies (2015) (0)
MEDU-32. ADVANCING PRECLINICAL MODELING OF HIGH RISK MEDULLOBLASTOMA BY PERFORMING CLINICALLY-RELEVANT RADIOTHERAPY ON PATIENT-DERIVED XENOGRAFTS (2017) (0)
Faculty Opinions recommendation of scRNA-seq in medulloblastoma shows cellular heterogeneity and lineage expansion support resistance to SHH inhibitor therapy. (2020) (0)
Faculty of 1000 evaluation for H3.3K27M Cooperates with Trp53 Loss and PDGFRA Gain in Mouse Embryonic Neural Progenitor Cells to Induce Invasive High-Grade Gliomas. (2018) (0)
Faculty Opinions recommendation of NK cell-mediated cytotoxicity contributes to tumor control by a cytostatic drug combination. (2019) (0)
Transforming Activity of the fms Oncogene (CSF-1 Receptor) (1987) (0)
Apoptosis in Myeloid Leukemia Cells The Chimeric E 2 A-HLF Transcription Factor Abrogates p 53-Induced (1998) (0)
Abstract 2289: Empowering point-and-click genomic analysis with large pediatric genomic reference data on St. Jude Cloud (2021) (0)
Author response: Zeb1 controls neuron differentiation and germinal zone exit by a mesenchymal-epithelial-like transition (2016) (0)
Faculty Opinions recommendation of Genomic Profiling of Childhood Tumor Patient-Derived Xenograft Models to Enable Rational Clinical Trial Design. (2020) (0)
Faculty Opinions recommendation of MLL4 Is Required to Maintain Broad H3K4me3 Peaks and Super-Enhancers at Tumor Suppressor Genes. (2018) (0)
Faculty Opinions recommendation of Endogenous human microRNAs that suppress breast cancer metastasis. (2008) (0)
Faculty Opinions recommendation of An epi-allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes in vivo. (2003) (0)
MB-32MEDULLOBLASTOMA GENOTYPE DICTATES BLOOD BRAIN BARRIER PHENOTYPE (2016) (0)
MEDB-42. GermlineElp1 deficiency promotes genomic instability and survival of granule neuron progenitors primed for SHH medulloblastoma pathogenesis (2022) (0)
Faculty Opinions recommendation of Deletions linked to TP53 loss drive cancer through p53-independent mechanisms. (2016) (0)
Molecular Cloning, Expression, and Chromosomal Localization of the Gene Encoding a Human Myeloid Membrane Antigen (gpl50) (2013) (0)
Faculty Opinions recommendation of Control of signaling-mediated clearance of apoptotic cells by the tumor suppressor p53. (2015) (0)
Author Correction: Failure of human rhombic lip differentiation underlies medulloblastoma formation (2022) (0)
David Levens Expression MYC Cellular MYCro Economics : Balancing MYC Function with Subject Collection MYC and the Pathway to Cancer MYC Degradation (2013) (0)
Faculty Opinions recommendation of A nucleolar mechanism controlling cell proliferation in stem cells and cancer cells. (2002) (0)
EPEN-07. OVEREXPRESSION AND MUTATIONS OF CXORF67 IN ‘INFANT-TYPE’ POSTERIOR FOSSA TYPE-A (PFA) EPENDYMOMAS (2018) (0)
Women in cancer research (2019) (0)
Faculty Opinions recommendation of Cdk4 and Cdk6 Couple the Cell-Cycle Machinery to Cell Growth via mTORC1. (2020) (0)
Delayed stochastic modelling of prokaryotic transcription with abortive initiation (0)
PDTM-02. TARGETING THE RB PATHWAY IN MEDULLOBLASTOMA (2019) (0)
Faculty Opinions recommendation of The Hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence. (2012) (0)
The Cold Spring Harbor Laboratory meeting on tyrosine phosphorylation and cell signaling. Cold Spring Harbor, NY, USA, May 12-16, 1999. (2000) (0)
The heme biosynthetic pathway plays a crucial role in N-MYC myeloid leukemias (2015) (0)
The Xenopus cyclin-dependent kinase inhibitor Ink4d is functionally conserved with murine p19Ink4d and is required for neural crest development (2007) (0)
Abstract PR02: Somatic CRISPR/Cas9-mediated tumor suppressor disruption enables versatile brain tumor modeling (2015) (0)
Combination of Ribociclib and Gemcitabine for the Treatment of Medulloblastoma (2022) (0)
From PROTAC to inhibitor: Structure-guided discovery of potent and orally bioavailable BET inhibitors. (2023) (0)
Cross-Species Epigenetics Identifies a Critial Role for VAV1 in the Maintenance of Sonic Hedgehog Subgroup Medulloblastomas (2014) (0)
Preclinical Modeling of Clinically Relevant Radiation Therapy for Treatment of High-Risk Medulloblastoma (2017) (0)
human chromosome 5. locus and its assignment to Molecular cloning of the c-fms (2013) (0)
Letter from Martine F. Roussel to Marshall W. Nirenberg (1996) (0)
ORIGIN OF THE ENDOGENOUS AVIAN RETROVIRUS, RAV-O (1980) (0)
Faculty Opinions recommendation of A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus. (2001) (0)
Abstract 3449: Epigenomics identifies conserved DNA methylation events associated with medulloblastoma development in humans and mice (2011) (0)
DDIS-11. A CK1a ACTIVATOR PENETRATES THE BRAIN, AND SHOWS EFFICACY AGAINST DRUG-RESISTANT METASTATIC MEDULLOBLASTOMA (2018) (0)
Mouse medulloblastoma driven by CRISPR activation of cellular Myc (2018) (0)
Abstract 314: Evaluation of effective drug combinations of sonidegib and ribociclib for treatment of Sonic hedgehog medulloblastoma using mathematical models of the cell cycle and Hedgehog pathways (2017) (0)
Molecular Cloning ofthec-fmsLocusandItsAssignment to HumanChromosome 5 (1983) (0)
Abstract 4927: Plasma and CNS pharmacokinetics of the CHK-1 inhibitor prexasertib (LY-2606368) in mice bearing orthotopic group 3 medulloblastoma (2018) (0)
Kratoch vill Cell Reports supplement (2015) (0)
Faculty Opinions recommendation of In vivo activation of the p53 pathway by small-molecule antagonists of MDM2. (2004) (0)
Abstract 3031: Characterization of gemcitabine triphosphate formation in mice to aid in the development of a translational tumor model (2020) (0)
Faculty Opinions recommendation of CHD5 is a tumor suppressor at human 1p36. (2007) (0)
Table of Contents (1990) (0)
ATP‐dependent efflux transporter ABCC4 is a positive regulator of the Sonic Hedgehog signaling pathway (2019) (0)
Differential expression pattern of the cell cycle inhibitors p19ink4d and p27kip1 by the cells of the neonatal rodent rostral migratory stream (2002) (0)
OMIC-03. TRANSLATIONAL CONTROL IN MYC AND MYCN MEDULLOBLASTOMA (2021) (0)
macrophages stimulated by colony-stimulating factor 1 Cloning and expression of murine interleukin-1 receptor antagonist in (2011) (0)
p27Kip1 enforces maintenance of quiescence in the mammalian ear and the pituitary gland (2011) (0)
A Preclinical Multidisciplinary Brain Tumor Board (2017) (0)
Faculty of 1000 evaluation for Genomic and functional approaches to understanding cancer aneuploidy. (2018) (0)
Faculty Opinions recommendation of p27 allosterically activates cyclin-dependent kinase 4 and antagonizes palbociclib inhibition. (2020) (0)
GE-40COMPARATIVE GENOMIC ANALYSES IDENTIFIES NON-SILENT MUTATIONS PRESENT IN BOTH MURINE AND HUMAN MEDULLOBLASTOMA (2014) (0)
EXTH-20. SYNGENEIC B7-H3-SPECIFIC CAR T-CELLS HAVE POTENT ANTI-BRAIN TUMOR ACTIVITY VIA LOCAL OR SYSTEMIC DELIVERY (2020) (0)
TNF Counterbalances the Emergence of M 2 Tumor Macrophages Graphical Abstract Highlights (0)
Atypical teratoid/rhabdoid tumoroids reveal subgroup-specific drug vulnerabilities. (2023) (0)
Abstract 1434: A mouse model of the most aggressive subgroup of human medulloblastoma (2012) (0)
LC-MS/MS method for quantitation of gemcitabine and its metabolite 2',2'-difluoro-2'-deoxyuridine in mouse plasma and brain tissue: Application to a preclinical pharmacokinetic study. (2021) (0)
Colony-stimulating factor 1-mediated regulation of a chimeric c-fms / v-fms receptor containing the v-fms-encoded tyrosine kinase domain ( colony-stimulating factor 1 receptor / v-fins oncogene / cell transformation ) (0)
Faculty Opinions recommendation of MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer. (2004) (0)
Abstract SY10-03: Cell of origin in pediatric medulloblastomas (2012) (0)
Targeting protein folding in N‐Myc‐driven medulloblastoma (2023) (0)
Faculty Opinions recommendation of Proliferation of functional hair cells in vivo in the absence of the retinoblastoma protein. (2005) (0)
Epigenetic Drivers in Pediatric Medulloblastoma (2017) (0)
Expertise des roulements coniques automatisée par l'analyse d'images (1997) (0)
Classification automatique des roulements coniques par reconnaissance des formes floue (1997) (0)
Origine des gènes transformants des rétrovirus aviaires des leucémies aiguës. (1980) (0)
Réduction des déchets de soins à l’hôpital : exemple des anticoagulants injectables par voie sous-cutanée (2014) (0)
Origin of transforming genes from avian retroviruses that cause acute leukaemia. (1980) (0)
Role and regulation of Cdk inhibitors in development and cancer (2009) (0)
PCM-15SOMATIC CRISPR/Cas9-MEDIATED TUMOR SUPPRESSOR DISRUPTION ENABLES VERSATILE BRAIN TUMOR MODELING (2016) (0)
STRUCTURE OF AVIAN DEFECTIVE LEUKAEMIA VIRUS GENOMES (1980) (0)
[Viral RNAs from cells infected by an oncornavirus. I. Characterization of viral RNAs associated with cytoplasmic particles]. (1977) (0)
Abstract 3444: Enforced expression of MycN and C-Myc induces different medulloblastoma subtypes (2011) (0)
Faculty Opinions recommendation of Increased gene dosage of Ink4a/Arf results in cancer resistance and normal aging. (2004) (0)
Loss of nuclear envelope phosphatase CTDNEP1 drives aggressive medulloblastoma by triggering MYC amplification and genomic instability (2021) (0)
MEDU-24. INTERROGATING THE ROLE OF EPIGENETIC REGULATORS IN MYC-DRIVEN MEDULLOBLASTOMA (2019) (0)
Loss of phosphatase CTDNEP1 potentiates aggressive medulloblastoma by triggering MYC amplification and genomic instability (2023) (0)
Nmyc Is Required For Proper Retinal Growth In Mice (2006) (0)
Abstract 5109: Somatic CRISPR/Cas9-mediated gene editing enables versatile brain tumor modeling (2018) (0)
Abstract 2749: Gemcitabine (GEM), a drug with clinical activity against pediatric solid tumors, demonstrates satisfactory CNS penetration in a preclinical murine medulloblastoma (MB) model. (2013) (0)
Faculty Opinions recommendation of Treatment of medulloblastoma with hedgehog pathway inhibitor GDC-0449. (2011) (0)

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