Martti Vaara
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Martti Vaara's Degrees
- PhD Management University of Helsinki
- Masters Economics University of Helsinki
- Bachelors Business Administration University of Helsinki
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(Suggest an Edit or Addition)Martti Vaara's Published Works
Published Works
- Molecular basis of bacterial outer membrane permeability. (1985) (2195)
- Agents that increase the permeability of the outer membrane. (1992) (1447)
- Safety of probiotics that contain lactobacilli or bifidobacteria. (2003) (547)
- Lactobacillus bacteremia during a rapid increase in probiotic use of Lactobacillus rhamnosus GG in Finland. (2002) (434)
- Sensitization of Gram-negative bacteria to antibiotics and complement by a nontoxic oligopeptide (1983) (215)
- Group of peptides that act synergistically with hydrophobic antibiotics against gram-negative enteric bacteria (1996) (185)
- Antibiotic-supersusceptible mutants of Escherichia coli and Salmonella typhimurium (1993) (177)
- Increased substitution of phosphate groups in lipopolysaccharides and lipid A of the polymyxin‐resistant pmrA mutants of Salmonella typhimurium: a 31P‐NMR study (1994) (175)
- Outer membrane permeability barrier to azithromycin, clarithromycin, and roxithromycin in gram-negative enteric bacteria (1993) (149)
- New approaches in peptide antibiotics. (2009) (126)
- Novel Polymyxin Derivatives Carrying Only Three Positive Charges Are Effective Antibacterial Agents (2008) (120)
- Outer Membrane Permeability Barrier in Escherichia coli Mutants That Are Defective in the Late Acyltransferases of Lipid A Biosynthesis (1999) (117)
- Etiological diagnosis of childhood pneumonia by use of transthoracic needle aspiration and modern microbiological methods. (2002) (108)
- Outer Membrane Permeability Barrier Disruption by Polymyxin in Polymyxin-Susceptible and -Resistant Salmonella typhimurium (1981) (106)
- Susceptibility of gram-negative bacteria to polymyxin B nonapeptide (1984) (105)
- Polymyxins and their novel derivatives. (2010) (105)
- The lipid A biosynthesis mutation lpxA2 of Escherichia coli results in drastic antibiotic supersusceptibility (1992) (104)
- A Novel Polymyxin Derivative That Lacks the Fatty Acid Tail and Carries Only Three Positive Charges Has Strong Synergism with Agents Excluded by the Intact Outer Membrane (2010) (102)
- Neonatal Candida parapsilosis outbreak with a high case fatality rate. (1995) (98)
- Carbapenemase-producing Enterobacteriaceae in Finland: the first years (2008-11). (2012) (97)
- Two Improved Methods for Obtaining Axenic Cultures of Cyanobacteria (1979) (94)
- Eight bacterial proteins, including UDP-N-acetylglucosamine acyltransferase (LpxA) and three other transferases of Escherichia coli, consist of a six-residue periodicity theme. (1992) (93)
- Potentiation of Antibiotic Activity by a Novel Cationic Peptide: Potency and Spectrum of Activity of SPR741 (2017) (92)
- New 16-plex PCR method for rapid detection of diarrheagenic Escherichia coli directly from stool samples (2009) (90)
- Streptococcus mutans Clonal Variation Revealed by Multilocus Sequence Typing (2007) (85)
- Binding of polymyxin B nonapeptide to gram-negative bacteria (1985) (82)
- Novel derivatives of polymyxins. (2013) (81)
- vanA and vanB Incorporate into an Endemic Ampicillin-Resistant Vancomycin-SensitiveEnterococcus faecium Strain: Effect on Interpretation of Clonality (1999) (81)
- Polymyxin Derivatives that Sensitize Gram-Negative Bacteria to Other Antibiotics (2019) (80)
- New Salmonella typhimurium mutants with altered outer membrane permeability (1984) (76)
- The novel hexapeptide motif found in the acyltransferases LpxA and LpxD of lipid A biosynthesis is conserved in various bacteria (1994) (67)
- A quantitative polymerase chain reaction assay for rapid detection of 9 pathogens directly from stools of travelers with diarrhea. (2013) (66)
- Polymyxins and Their Potential Next Generation as Therapeutic Antibiotics (2019) (62)
- Partitioning of hydrophobic probes into lipopolysaccharide bilayers. (1990) (59)
- Poor antibacterial effect of ropivacaine: comparison with bupivacaine. (1999) (55)
- Human kidney on a chip assessment of polymyxin antibiotic nephrotoxicity. (2018) (54)
- Salmonella typhimurium and Escherichia coli mutants with increased outer membrane permeability to hydrophobic compounds. (1989) (54)
- Levofloxacin does not decrease mortality in Staphylococcus aureus bacteraemia when added to the standard treatment: a prospective and randomized clinical trial of 381 patients (2006) (53)
- Sodium hexametaphosphate sensitizes Pseudomonas aeruginosa, several other species of Pseudomonas, and Escherichia coli to hydrophobic drugs (1989) (52)
- The outer membrane permeability-increasing action of deacylpolymyxins. (1991) (50)
- Isolation, cloning, and primary structure of a cationic 16-kDa outer membrane protein of Salmonella typhimurium. (1989) (50)
- Distribution of streptococcal inhibitor of complement variants in pharyngitis and invasive isolates in an epidemic of serotype M1 group A Streptococcus infection. (2001) (49)
- Rapid Molecular Characterization of Acinetobacter baumannii Clones with rep-PCR and Evaluation of Carbapenemase Genes by New Multiplex PCR in Hospital District of Helsinki and Uusimaa (2014) (49)
- Polyamines as constituents of the outer membranes of Escherichia coli and Salmonella typhimurium (1991) (48)
- Polymyxin B nonapeptide complexes with lipopolysaccharide (1983) (47)
- A Novel Enzyme Application for Corn Wet Milling (1988) (45)
- Effect of small cationic leukocyte peptides (defensins) on the permeability barrier of the outer membrane (1988) (45)
- Overgrowth of Enterococcus faecium in the feces of patients with hematologic malignancies. (1996) (44)
- Detection of virulence genes of Clostridium difficile by multiplex PCR (2009) (44)
- Novel polymyxin derivatives are less cytotoxic than polymyxin B to renal proximal tubular cells (2012) (43)
- Report of four cases ofYersinia pseudotuberculosis septicemia and a literature review (1995) (43)
- Costs of an outbreak of meticillin-resistant Staphylococcus aureus. (2007) (42)
- Accurate and Rapid Identification of Candida spp. Frequently Associated with Fungemia by Using PCR and the Microarray-Based Prove-it Sepsis Assay (2012) (42)
- Efficacy of a novel PCR- and microarray-based method in diagnosis of a prosthetic joint infection (2014) (42)
- Polymyxin B octapeptide and polymyxin B heptapeptide are potent outer membrane permeability-increasing agents. (1992) (41)
- Burkholderia pseudomallei infections in Finnish tourists injured by the December 2004 tsunami in Thailand. (2005) (40)
- Antimicrobial Susceptibilities of Campylobacter Strains Isolated from Finnish Subjects Infected Domestically or from Those Infected Abroad (2003) (40)
- Molecular characterization of methicillin-resistant Staphylococcus epidermidis strains from bacteraemic patients. (2008) (39)
- Interleukin 1 receptor antagonist and E-selectin concentrations: a comparison in patients with severe acute pancreatitis and severe sepsis. (1999) (38)
- rfaP mutants of Salmonella typhimurium. (1989) (37)
- First isolations of KPC-2-carrying ST258 Klebsiella pneumoniae strains in Finland, June and August 2009. (2009) (37)
- Real‐time multiplex PCR assay for detection of Yersinia pestis and Yersinia pseudotuberculosis (2009) (36)
- Pharmacokinetics of novel antimicrobial cationic peptides NAB 7061 and NAB 739 in rats following intravenous administration. (2009) (36)
- Capnocytophaga canimorsus septicemia: Fifth report of a cat-associated infection and five other cases (1995) (36)
- Mutation at the position 2058 of the 23S rRNA as a cause of macrolide resistance in Streptococcus pyogenes (2004) (35)
- Antifungal Susceptibility and Virulence Attributes of Bloodstream Isolates of Candida from Hong Kong and Finland (2011) (34)
- Persistence of a multiresistant clone of Staphylococcus epidermidis in a neonatal intensive-care unit for a four-year period. (1995) (34)
- Susceptibility of carbapenemase-producing strains of Klebsiella pneumoniae and Escherichia coli to the direct antibacterial activity of NAB739 and to the synergistic activity of NAB7061 with rifampicin and clarithromycin. (2010) (34)
- Antimicrobial activity of the novel polymyxin derivative NAB739 tested against Gram-negative pathogens. (2013) (33)
- Shiga Toxin-Producing Escherichia coli O100:H–: stx2e in Drinking Water Contaminated by Waste Water in Finland (2011) (33)
- The novel polymyxin derivative NAB739 is remarkably less cytotoxic than polymyxin B and colistin to human kidney proximal tubular cells. (2013) (33)
- The Ssc protein of enteric bacteria has significant homology to the acyltransferase Lpxa of lipid A biosynthesis, and to three acetyltransferases (1991) (32)
- Analysis of polyamines as their dabsyl derivatives by reversed-phase high-performance liquid chromatography. (1987) (32)
- Effective Inhibition of Cardiolipin‐Binding Antibodies in Gram‐Negative Infections by Bacterial Lipopolysaccharide (1988) (31)
- Structure–activity studies on novel polymyxin derivatives that carry only three positive charges (2010) (29)
- Identification and sequence analysis of the gene mutated in the conditionally lethal outer membrane permeability mutant SS‐C of Salmonella typhimurium. (1991) (29)
- First isolation of Clostridium difficile PCR ribotype 027 in Finland. (2007) (29)
- New polymyxin derivatives that display improved efficacy in animal infection models as compared to polymyxin B and colistin (2018) (29)
- Novel polymyxin derivatives are effective in treating experimental Escherichia coli peritoneal infection in mice. (2010) (29)
- Mutants carrying conditionally lethal mutations in outer membrane genes omsA and firA (ssc) are phenotypically similar, and omsA is allelic to firA (1992) (28)
- Intramucosal pH and endotoxin and cytokine release in severe acute pancreatitis. (2000) (28)
- The outer membrane permeability-increasing action of linear analogues of polymyxin B nonapeptide. (1991) (28)
- Complete sequence of the ompH gene encoding the 16-kDa cationic outer membrane protein of Salmonella typhimurium. (1990) (28)
- Increased substitution of phosphate groups in lipopolysaccharides and lipid A of polymyxin-resistant mutants of Salmonella typhimurium and Escherichia coli. (1995) (27)
- Chain length heterogeneity of lipopolysaccharide released from Salmonella typhimurium by ethylenediaminetetraacetic acid or polycations. (1986) (26)
- Chemical structure of the lipid A component of lipopolysaccharides of the genus Pectinatus. (1994) (25)
- The ompH gene of Yersinia enterocolitica: cloning, sequencing, expression, and comparison with known enterobacterial ompH sequences (1991) (25)
- A selective broth enrichment combined with real‐time nuc‐mecA‐PCR in the exclusion of MRSA (2010) (25)
- Comparison of repetitive extragenic palindromic sequence-based PCR with PCR ribotyping and pulsed-field gel electrophoresis in studying the clonality of Clostridium difficile. (2011) (23)
- Bacteria, Phages and Septicemia (2007) (23)
- The outer membrane as the penetration barrier against mupirocin in gram-negative enteric bacteria. (1992) (23)
- Clinical "pneumococcal pneumonia" due to Moraxella osloensis: case report and a review. (2001) (22)
- Lipid A--Target for Antibacterial Drugs (1996) (22)
- The lipid A biosynthesis deficiency of the Escherichia coli antibiotic-supersensitive mutant LH530 is suppressed by a novel locus, ORF195. (1997) (21)
- Comparison of risk factors and outcome in patients with Enterococcus faecalis vs Enterococcus faecium bacteraemia. (1998) (21)
- Nosocomial bloodstream infections in children: an 8-year experience at a tertiary-care hospital in Finland. (2008) (21)
- The outer membrane of lipid A-deficient Escherichia coli mutant LH530 has reduced levels of OmpF and leaks periplasmic enzymes. (1997) (20)
- Antimicrobial susceptibility of Salmonella typhimurium carrying the outer membrane permeability mutation SS-B (1990) (20)
- Bacteremia caused byBrevibacterium species in an immunocompromised patient (1995) (19)
- Does polymyxin B nonapeptide increase outer membrane permeability in antibiotic supersensitive enterobacterial mutants (1985) (18)
- Structure–activity studies on polymyxin derivatives carrying three positive charges only reveal a new class of compounds with strong antibacterial activity (2017) (18)
- Preferential synthesis of heptaacyl lipopolysaccharide by the ssc permeability mutant of Salmonella typhimurium. (1992) (18)
- Primary structure and expression of the Ssc-protein of Salmonella typhimurium. (1990) (17)
- Defective biosynthesis of the lipid A component of temperature-sensitive firA (omsA) mutant of Escherichia coli. (1993) (16)
- Susceptibility of gram-negative bacteria to the synergistic bactericidal action of serum and polymyxin B nonapeptide. (1986) (16)
- Evaluation of a commercial MRSA assay when multiple MRSA strains are causing epidemics (2009) (15)
- Polymyxin derivatives NAB739 and NAB815 are more effective than polymyxin B in murine Escherichia coli pyelonephritis (2018) (15)
- Increased resistance among Staphylococcus epidermidis isolates in a large teaching hospital over a 12-year period. (1996) (15)
- Reversible binding of Salmonella typhimurium lipopolysaccharides by immobilized protamine. (1987) (14)
- Clonality behind the increase of multidrug-resistance among non-invasive pneumococci in Southern Finland (2012) (14)
- Increase of prostate biopsy-related bacteremic complications in southern Finland, 2005–2013: a population-based analysis (2016) (14)
- Comparison of the phenotypes of the lpxA and lpxD mutants of Escherichia coli. (1995) (14)
- Effect of ionic strength on polymyxin resistance of pmrA mutants of Salmonella (1981) (12)
- Plasma endotoxin and cytokine levels in neutropenic and non-neutropenic bacteremic patients (1995) (12)
- The polymyxin derivative NAB739 is synergistic with several antibiotics against polymyxin-resistant strains of Escherichia coli, Klebsiella pneumoniae and Acinetobacter baumannii (2019) (12)
- The effect of oligolysines Lys-3, Lys-4, and Lys-5 on the outer membrane permeability of Pseudomonas aeruginosa. (1990) (11)
- Phosphate groups in lipopolysaccharides of Salmonella typhimurium rfaP mutants (1997) (11)
- Polymyxin B nonapeptide sensitizes Escherichia coli to valinomycin and A23187 ionophores (1984) (11)
- Analytical and preparative high-performance liquid chromatography of the papain-cleaved derivative of polymyxin B. (1988) (11)
- Using Chemical Probes to Assess the Feasibility of Targeting SecA for Developing Antimicrobial Agents against Gram‐Negative Bacteria (2016) (11)
- An outbreak of CTX-M-15 -producing Escherichia coli, Enterobacter cloacae, and Klebsiella in a children's hospital in Finland (2014) (10)
- Emergence of extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae during the years 2000 and 2004 in Helsinki, Finland. (2010) (10)
- Comparative activity of rifabutin and rifampicin against gram-negative bacteria that have damaged or defective outer membranes. (1993) (9)
- Outer membrane phospholipase is not the mediator in the bactericidal or outer membrane permeability-increasing action of polycations (1983) (9)
- Increased resistance amongStaphylococcus epidermidis isolates in a large teaching hospital over a 12-year period (1996) (8)
- Biological activities of lipopolysaccharides from Pectinatus cerevisiophilus (1984) (8)
- Lipopolysaccharides of three classes of supersensitive mutants of Salmonella typhimurium (1985) (8)
- Applicability of DiversiLab repetitive sequence-based PCR method in epidemiological typing of enterohemorrhagic Escherichia coli (EHEC). (2013) (7)
- Infection, anticardiolipin and thrombosis. (1987) (6)
- The nucleotide and deduced amino acid sequence of the cationic 19 kDa outer membrane protein OmpH of Yersinia pseudotuberculosis. (1991) (6)
- Outer membrane permeability of the antibiotic-supersusceptible lipid A mutants of Escherichia coli to hydrophobic steroid probes. (1999) (6)
- Isolation and characterization of Streptococcus mitis from blood of child with osteomyelitis. (2011) (6)
- Clinical isolates of Pseudomonas aeruginosa from superficial skin infections have different physiological patterns. (2013) (5)
- Plasma interleukin-8, interleukin-10, and E-selectin levels in neutropenic and non-neutropenic bacteremic patients (1997) (5)
- Bartonella quintana and Bartonella pediococcus Infection after Aortic Valve Replacement. (2008) (5)
- LPS greatly enhances the antibody response to hapten-polysaccharide conjugates, but not to hapten-protein conjugates. (1983) (4)
- Costs of outbreak of Methicillin-Resistant Staphylococcus Aureus (2007) (4)
- Low levels of cytokines and endotoxin in a fatal case of myocardial depression and septic shock due to Yersinia pseudotuberculosis. (1995) (4)
- Non-tuberculous Mycobacteria can Cause Disseminated Mycobacteriosis in Cats (2018) (4)
- Effect of Ssc protein mutations on the outer membrane permeability barrier function in Salmonella typhimurium: a study using ssc mutant alleles made by site-directed mutagenesis. (1992) (4)
- Emergence of ESBL-producing Escherichia coli and Klebsiella pneumoniae isolates during the years 2000 and 2004 in Helsinki, Finland (2009) (3)
- [Yersinia Pseudotuberculosis, a rare cause of septicemia]. (1996) (3)
- [New antibacterial agents]. (1999) (3)
- In vitro activity of antifungal azoles againstHelicobacter pylori (1992) (3)
- Evaluation of Antimicrobial Therapy of Blood Culture Positive Healthcare-Associated Infections in Children (2015) (2)
- Quantitative antimicrobial susceptibility testing of outer membrane-altered mutant bacteria by the E test. (1993) (2)
- Comparative activity of tigecycline and tetracycline on Gram-negative and Gram-positive bacteria revealed by a multicentre study in four North European countries (2011) (2)
- Do salicylates and ascorbate increase the outer membrane permeability to hydrophobic antibiotics in Pseudomonas aeruginosa? (1990) (2)
- Lipopolysaccharide and the Permeability of the Bacterial Outer Membrane (2020) (2)
- Polymyxins Targeting the Outer Membrane of Gram-negative Bacteria (2016) (2)
- Clonality behind the increase of multidrug-resistance among non-invasive pneumococci in Southern Finland (2011) (1)
- Susceptibility and virulent attributes of Candida from Hong Kong and Finland (2010) (1)
- enteric bacteria. hydrophobic antibiotics against gram-negative Group of peptides that act synergistically with (2013) (1)
- Antimicrobial Resistance in Finland - Finres 1997-2010 (2013) (1)
- Excretion of the Polymyxin Derivative NAB739 in Murine Urine (2020) (1)
- Polymyxinderivat and uses thereof (2016) (1)
- Disseminated Mycobacterium malmoense Infection in a Cat (2016) (1)
- Susceptibility ofGram-Negative Bacteria toPolymyxin B Nonapeptide (1984) (1)
- Old and Novel Polymyxins Against Serious Gram-Negative Infections (2014) (1)
- Pneumococcal serotype distribution in invasive paediatric disease in Southern Finland before the introduction of vaccine (2010) (1)
- [Listening at Tosca on the balcony. The secret of heavenly sound--a randomized, cross-sectional study]. (2003) (1)
- P-NMR characterization of lipopolysaccharide released from Salmonella typhimurium by ethylenediaminetetraacetic acid (1999) (0)
- In-vitro and in-vivo activity of novel polymyxin derivatives in combination with other antimicrobial agents against multi-drug resistant Acinetobacter baumannii (MDRAB) (2013) (0)
- 156 Increasing incidence of blood-culture positive infectious complications following transrectal prostate biopsies (2016) (0)
- [Development of antibacterial drugs]. (1991) (0)
- Polymyxin derivatives and applications thereof (2007) (0)
- Water-soluble enzymatic hydrolyzate of a cellulose derivative as well as the process for its preparation (1990) (0)
- Short Communication BACILLUS SUB TILIS TmrB PROTEIN CONFERS RESISTANCE TO TUNICAMYCIN ON ESCHERICHIA COLI (2006) (0)
- [The diseases of the future]. (1997) (0)
- [Postpartum gas gangrene]. (1993) (0)
- Distribution of streptococcal inhibitor of compelement variants in pharyngitis and invasive isolates in an epidemic of serotype M1 Group A (2001) (0)
- Polymyxin derivatives and their uses (2007) (0)
- P3.11 Epidemiology of Extended-Spectrum Beta-Lactamase (ESBL) Producing Escherichia Coli (E. coli) in Helsinki City in 2000-2004 (2006) (0)
- [Sources for antibacterial drugs are not drying up]. (1998) (0)
- Macerate procedure for cereals with a new enzyme preparation. (1988) (0)
- Performance evaluation and further development of the PCR and microarray-based Prove-it™ Sepsis assay (2009) (0)
- Hydrolyzate of cellulose derivative and production thereof (1990) (0)
- [Not Available]. (2007) (0)
- [Penicillin-resistant pneumococci are coming--are you prepared?]. (1994) (0)
- Influence of severity of illness on the effects of eritoran tetrasodium ( E 5564 ) , a TLR 4 antagonist , in patients with severe sepsis (2015) (0)
- [Evolution of pathogenic micro-organisms as a challenge for medicine]. (2009) (0)
- Corrigendum: Polymyxins and Their Potential Next Generation as Therapeutic Antibiotics (2019) (0)
- Future diagnosis of sepsis – Authors' reply (2010) (0)
- Antimikrobiellejä and antiinflammatory compounds (1996) (0)
- Research letterLipopolysaccharides of three classes of supersensitive mutants of Salmonella typhimurium (1985) (0)
- A method for dissolving and processing of corn and sorghum (1988) (0)
- [Not Available]. (2007) (0)
- Method of producing isolates and soy protein concentrates low in phytate and phytate free. (1990) (0)
- [Endocarditis caused by Gemella bacteria infection]. (2006) (0)
- A method of soaking of cereal with a new enzyme composition. (1988) (0)
- Comparison of different methicillin-resistant Staphylococcus aureus (MRSA) typing methods when poorly distinguishable isolates are causing epidemics (2011) (0)
- Polymyksiinijohdannaiset, which is a short fatty acid tail, and uses thereof (2008) (0)
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