Marvin Makinen
#34,913
Most Influential Person Now
American biochemist
Marvin Makinen's AcademicInfluence.com Rankings
Marvin Makinenbiology Degrees
Biology
#2417
World Rank
#3835
Historical Rank
#1081
USA Rank
Biochemistry
#504
World Rank
#590
Historical Rank
#175
USA Rank
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Biology
Marvin Makinen's Degrees
- PhD Biochemistry University of California, Berkeley
- Bachelors Chemistry University of California, Berkeley
Why Is Marvin Makinen Influential?
(Suggest an Edit or Addition)According to Wikipedia, Marvin William Makinen has been a member of the faculty at the University of Chicago since 1974 and is a founding member of the Human Rights Board at the university. Education Born in Chassell, Michigan, Makinen earned a B.A. at the University of Pennsylvania in 1961, an M.D. at the University of Pennsylvania School of Medicine in 1968, and a D. Phil. at the University of Oxford in 1976. He is presently professor in the department of biochemistry and molecular biology at the University of Chicago, and has served as chairman of the department from 1988 to 1993. His primary research interests in molecular biophysics and biochemistry are in mechanisms of enzymes and the structural basis of enzyme action.
Marvin Makinen's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Low‐frequency Raman spectra of lysozyme (1976) (121)
- Reactivity and cryoenzymology of enzymes in the crystalline state. (1977) (95)
- Structure of carboxymyoglobin in crystals and in solution. (1979) (91)
- Ground term splitting of high-spin cobalt(2+) ion as a probe of coordination structure. 1. Dependence of the splitting on coordination geometry (1985) (78)
- In vivo spin-label murine pharmacodynamics using low-frequency electron paramagnetic resonance imaging. (1996) (66)
- Catalytic role of the metal ion of carboxypeptidase A in ester hydrolysis. (1979) (63)
- Coordination environment of the active-site metal ion of liver alcohol dehydrogenase. (1981) (53)
- The Structural Basis of Action of Vanadyl (VO2+) Chelates in Cells. (2014) (52)
- Heme-heme orientation and electron transfer kinetic behavior of multisite oxidation-reduction enzymes. (1983) (48)
- Catalytic and structural role of the metal ion in dUTP pyrophosphatase (2003) (47)
- POLARIZED SINGLE CRYSTAL ABSORPTION SPECTRA OF CARBOXY‐ AND OXYHEMOGLOBIN (1973) (46)
- Protonation of the beta-lactam nitrogen is the trigger event in the catalytic action of class A beta-lactamases. (2000) (45)
- Mechanism of action of carboxypeptidase A in ester hydrolysis. (1976) (44)
- Structural Origins of the Insulin-mimetic Activity of Bis(acetylacetonato)oxovanadium(IV)* (2002) (43)
- Erratum: The electronic structure and coordination geometry of the oxyheme complex in myoglobin (1978) (43)
- Neutral metal-bound water is the base catalyst in liver alcohol dehydrogenase. (1983) (42)
- The vanadyl (VO2+) chelate bis(acetylacetonato)oxovanadium(IV) potentiates tyrosine phosphorylation of the insulin receptor (2005) (41)
- ENDOR-determined solvation structure of vanadyl(2+) in frozen solutions (1988) (40)
- Multi-block poloxamer surfactants suppress aggregation of denatured proteins. (2008) (38)
- Overexpression and biosynthetic deuterium enrichment of TEM-1 beta-lactamase for structural characterization by magnetic resonance methods. (2000) (37)
- Hydrolysis of esters by carboxypeptidase A requires a penta-coordinate metal ion. (1982) (37)
- Optical spectra and electronic structure of flavine mononucleotide in flavodoxin crystals. (1975) (36)
- Ground term splitting of high-spin cobalt(2+) ion as a probe of coordination structure. 2. The ligand environment of the active site metal ion of carboxypeptidase A in ester hydrolysis (1985) (36)
- Optically Detected Conformational Changes in Haemoglobin Single Crystals (1974) (35)
- High-Frequency Electron Paramagnetic Resonance Studies of VO2+ in Low-Temperature Glasses (1999) (31)
- Molecular geometry of vanadyl-adenine nucleotide complexes determined by EPR, ENDOR, and molecular modeling (1992) (30)
- Catalytic conformation of carboxypeptidase A. The structure of a true reaction intermediate stabilized at subzero temperatures. (1983) (27)
- Specificity of interaction of haptoglobin with mammalian hemoglobin. (1972) (24)
- Biological Magnetic Resonance (2002) (23)
- New vanadium-based magnetic resonance imaging probes: clinical potential for early detection of cancer (2009) (23)
- Determination of the zero-field splitting constants of high-spin metalloproteins by a continuous-wave microwave saturation technique (1982) (22)
- ENDOR-determined molecular geometries of spin-labeled fluoroanilides in frozen solution (1988) (21)
- Catalytic conformation of carboxypeptidase A. Structure of a true enzyme reaction intermediate determined by electron nuclear double resonance. (1994) (20)
- Structure and conformation of bis(acetylacetonato)oxovanadium(IV) and bis(maltolato)oxovanadium(IV) in solution determined by electron nuclear double resonance spectroscopy. (2005) (19)
- ENDOR structural characterization of a catalytically competent acylenzyme reaction intermediate of wild-type TEM-1 beta-lactamase confirms glutamate-166 as the base catalyst. (2001) (19)
- Evidence by gel filtration at subzero temperatures for the covalent reaction intermediate of carboxypeptidase A in ester hydrolysis (1982) (18)
- Circular dichroism and electron paramagnetic resonance of the haptoglobin-hemoglobin complex. (1971) (18)
- Fe-O2 bonding and oxyheme structure in myoglobin. (1978) (17)
- Structure and conformation of spin-labeled amino acids in frozen solutions determined by electron nuclear double resonance. 1. Methyl N-(2,2,5,5-tetramethyl-1-oxypyrrolinyl-3-carbonyl)-L-alanate, a molecule with a single preferred conformation (1990) (16)
- Mg2+ Is Not Catalytically Required in the Intrinsic and Kirromycin-stimulated GTPase Action of Thermus thermophilus EF-Tu* (2001) (16)
- The pH variation of steady-state kinetic parameters of site-specific Co(2+)-reconstituted liver alcohol dehydrogenase. A mechanistic probe for the assignment of metal-linked ionizations. (1991) (15)
- Structure and conformation of spin-labeled amino acids in frozen solutions determined by electron nuclear double resonance. 2. Methyl N-(2,2,5,5-tetramethyl-1-oxypyrrolinyl-3-carbonyl)-L-tryptophanate, a molecule with multiple conformations (1990) (15)
- NMR AND ENDOR CONFORMATIONAL STUDIES OF THE VANADYL GUANOSINE 5'-MONOPHOSPHATE COMPLEX IN HYDROGEN-BONDED QUARTET ASSEMBLIES (1995) (14)
- ENDOR study of Gd3+ complexes in frozen solutions (1986) (13)
- Electron microscopy of fibers and discs of hemoglobin S having sixfold symmetry. (1977) (13)
- STRUCTURE, CONFORMATION, AND PROBABLE MECHANISM OF HYDROLYSIS OF A SPIN-LABELED PENICILLIN REVEALED BY ELECTRON NUCLEAR DOUBLE RESONANCE SPECTROSCOPY (1995) (12)
- ENDOR of Spin Labels for Structure Determination: From Small Molecules to Enzyme Reaction Intermediates (2002) (12)
- FACILE SYNTHESIS OF 3-FORMYL-2,2,5,5-TETRAMETHYL-1-OXYPYRROLINE (1999) (12)
- Letter to the Editor: 1H, 13C and 15N backbone resonance assignments for TEM-1, a 28.9 kDa β-lactamase from E. coli (2004) (11)
- A Surfactant Copolymer Facilitates Functional Recovery of Heat‐Denatured Lysozyme (2005) (11)
- The effective position of the electronic point dipole of the nitroxyl group of spin labels determined by endor spectroscopy (1991) (11)
- Conformational Changes in Spin-Labeled Cephalosporin and Penicillin upon Hydrolysis Revealed by Electron Nuclear Double Resonance Spectroscopy (1997) (10)
- Structural basis and dynamics of the fiber-to-crystal transition of sickle cell hemoglobin. (1984) (10)
- The vanadyl ion: molecular structure of coordinating ligands by electron paramagnetic resonance and electron nuclear double resonance spectroscopy. (1995) (9)
- Electron microscope study of the kinetics of the fiber-to-crystal transition of sickle cell hemoglobin. (1980) (9)
- ENDOR studies of VO2+: probing protein-metal ion interactions in nephrocalcin. (2000) (9)
- ENDOR Determined Structure of a Complex of α-Chymotrypsin with a Spin-Labeled Transition-State Inhibitor Analogue (1998) (9)
- Structure at the active site of an acylenzyme of alpha-chymotrypsin and implications for the catalytic mechanism. An electron nuclear double resonance study. (1994) (9)
- Assignment of proton endor resonances of nitroxyl spin-labels in frozen solution. (1990) (8)
- Synthesis of conjugated polyene carbonyl derivatives of nitroxyl spin-labels and determination of their molecular structure and conformation by electron nuclear double resonance (1993) (8)
- Electron nuclear double resonance determined structures of enzyme reaction intermediates: structural evidence for substrate destabilization. (1998) (8)
- Synthesis of chromophoric, spin label enzyme substrates useful for cryoenzymology. (1979) (7)
- Structure and conformation of spin-labeled methyl L-phenylalanate and L-phenylalanine determined by electron nuclear double resonance spectroscopy (1991) (7)
- The vanadyl chelate bis(acetylacetonato)oxovanadium(IV) increases the fractional uptake of 2-(fluorine-18)-2-deoxy-D-glucose by cultured human breast carcinoma cells. (2013) (7)
- Structure and conformation of the nitroxyl spin‐label ethyl 3‐(2,2,5,5‐tetramethylpyrrolinyl‐1‐oxyl)‐propen‐2‐oate determined by electron nuclear double resonance: Comparison with the structure of a spin‐label substrate of carboxypeptidase A (1990) (6)
- The second derivative electronic absorption spectrum of cytochrome c oxidase in the Soret region. (1999) (6)
- Cryostat for enzymology in the subzero temperature range. (1978) (6)
- Protonation of the b -lactam nitrogen is the trigger event in the catalytic action of class A b -lactamases (2000) (6)
- Polarized single-crystal absorption spectra of cobalt2+-carboxypeptidase A (1986) (5)
- Infrared detector system for polarized single‐crystal absorption spectra with a microspectrophotometer (1985) (5)
- Kinetic characterization of the inhibition of protein tyrosine phosphatase-1B by Vanadyl (VO2+) chelates (2017) (5)
- Structure of spin-labeled methylmethanethiolsulfonate in solution and bound to TEM-1 beta-lactamase determined by electron nuclear double resonance spectroscopy. (2002) (5)
- The catalytic action of Zn2+-metalloenzymes requires a penta-coordinate metal-OH2 complex (1984) (4)
- Multiple rotamers of 3-(2,2,5,5-tetramethyl-1-oxypyrrolinyl)-2-propen-1-ol, a stereospecific substrate of liver alcohol dehydrogenase: determination of molecular structure and conformation by electron nuclear double resonance (1993) (4)
- Chromophoric spin-labeled β-lactam antibiotics for ENDOR structural characterization of reaction intermediates of class A and class C β-lactamases (2004) (4)
- Application of Angle-Selected Electron Nuclear Double Resonance to Characterize Structured Solvent in Small Molecules and Macromolecules (2005) (3)
- Structure and conformation of nitroxyl spin-label compounds in frozen solutions by electron nuclear double resonance spectroscopy (1992) (3)
- The crystal and molecular structure of 1‐naphthyl 2',3',4',6'‐tetra‐O‐acetyl‐β‐d‐glucopyranoside (1978) (3)
- A COMMENT ON THE ELECTRONIC STRUCTURE OF THE Fe-O2 GROUP IN OXYHEME (1979) (3)
- Molecular spectroscopy of high-spin Co(II). Polarized single crystal electronic absorption spectra of structurally defined tetracoordinate complexes with sulfur-donor ligands (1987) (3)
- Preliminary investigation of 48V-labeled VO(acac)2 for cancer imaging: An initial proof-of-concept study. (2022) (3)
- Interaction of the Vanadyl (VO2+) Cation with Guanosine Nucleotides and Elongation Factor Tu (1998) (2)
- Enhancement of insulin action by bis (acetylacetonato )oxovanadium (IV) occurs through uncompetitive inhibition of protein tyrosine phosphatase-1B (2007) (2)
- Kinetically specific spin-label substrates of liver alcohol dehydrogenase and of liver aldehyde dehydrogenase. (1993) (2)
- POLARIZED SINGLE CRYSTAL ABSORPTION SPECTRA OF THE REACTION PRODUCTS OF SPERM WHALE MYOGLOBIN WITH O2, OH−, AND H2O21 (1979) (1)
- Flavins and flavoproteins. Proceedings of the Third International Symposium of Flavins and Flavoproteins edited by H. Kamin (1972) (1)
- Validation of nitroxyl spin‐label force‐field parameters through molecular dynamics simulations (2001) (1)
- ENDOR-Determined Solvation Structure of VO2+ in Frozen Solutions (1988) (1)
- Chromophoric spin-labeled beta-lactam antibiotics for ENDOR structural characterization of reaction intermediates of class A and class C beta-lactamases. (2004) (1)
- Structural and spectroscopic studies of lysozyme (1976) (1)
- The influence of oxygen-17 enriched oxygen-donor ligands on the electronic spin relaxation behaviour of paramagnetic metal ions (1992) (1)
- Solvent structure and enzyme activity. (1985) (1)
- V-48 labeled VO(acac)2for hybrid PET/MR imaging of cancer (2019) (1)
- Neutral metal-boundiwater isthebasecatalyst inliver alcohol dehydrogenase (1983) (0)
- Multiple Rotamers of 3‐(2,2,5,5‐Tetramethyl‐1‐oxopyrrolinyl)‐2‐propen‐ 1‐ol, a Stereospecific Substrate of Liver Alcohol Dehydrogenase: Determination of Molecular Structure and Conformation by Electron Nuclear Double Resonance. (1993) (0)
- The Crystal and Molecular Structure of l-Naphthyl 2 ' , 3 ' , 4 ' , 6 '-Tetra-O-acctyl-flD-glucopyranoside (2001) (0)
- Structure and Conformation of Spin‐Labeled Methyl L‐Phenylalanate and L‐Phenylalanine Determined by Electron Nuclear Double Resonance Spectroscopy. (1992) (0)
- The Wallenberg Affair and the Onset of the Cold War (2017) (0)
- NEW VANADIUM-BASED MRI PROBES FOR EARLY DETECTION OF CANCER (2006) (0)
- OPTICAL DETECTION OF HEME LIGAND CONFIGURATION IN SPERM WHALE MYOGLOBIN (1978) (0)
- ELECTRON MICROSCOPY OF FIBERS AND CRYSTALS OF A DEOXYGENATED PLATINUM DERIVATIVE OF HEMOGLOBIN S (1978) (0)
- Mechanism ofaction ofcarboxypeptidase Ainester hydrolysis (acyl-enzyme intermediate/cryoenzympology/enzyme (1976) (0)
- 115 High‐Resolution MRI Relaxation of Water Protons in Proteins and Electroporated Rat Muscles (2008) (0)
- Incorporation of isotopic oxygen into the carbonyl group of esters and amides (1982) (0)
- Kinetic characterization of the inhibition of protein tyrosine phosphatase-1B by Vanadyl (VO2+) chelates (2017) (0)
- Inhibition of protein tyrosine phosphatase-1B in vitro and in vivo (2017) (0)
- Electron microscope study of the kinetics of the fiber-to-crystal transition of sickle cell hemoglobin (mutant hemoglobins/nucleation kinetics/optical diffraction/protein self-assembly/sickle cell anemia) (2016) (0)
- The Polarized Single Crystal Electronic Absorption Spectrum of Phosphorylase b (1987) (0)
- Molecular Spectroscopy of High-Spin Co(II). Polarized Single Crystal Electronic Absorption Spectra of Structurally Defined Tetracoordinate Complexes with Sulfur-Donor Ligands. (1987) (0)
- Introductory Remarks: The Molecular Dynamics of Dysfunction and Aggregation of Mutant Hemoglobins (1981) (0)
- Endor Determined Structure and Conformation of Spin-Labeled Methyl L-Phenylalanate in Frozen Solutions (1990) (0)
- Charge-Transfer States and Redox Properties of Heme Complexes in Proteins (1982) (0)
- Catalysis by Zn2+-metalloenzymes proceeds via a penta-coordinate metal-OH2 complex (1983) (0)
- Endor determines structure and conformation of ethyl 3-(2,2,5,5-tetramethylpyrrolinyl-1-oxyl)propene-oate: Comparison with the structure of a spin-label substrate of carboxypeptidase A (1989) (0)
- Neutral metal-bound water is the b alcohol dehydrogenase (electron paramagnetic resonance/oxygen-17/pH dependence of kin( (2016) (0)
- Preferential sequestration of a vanadyl chelate by cancer tissue facilitates 2-(fluorine-18)-2- deoxyglucose (FDG) uptake for positron emission tomography (PET) imaging (2015) (0)
- Synthesis of Conjugated Polyene Carbonyl Derivatives of Nitroxyl Spin‐ Labels and Determination of Their Molecular Structure and Conformation by Electron Nuclear Double Resonance. (1993) (0)
- The catalytically competent coordination environment of the active site metal ion of liver alcohol dehydrogenase (1983) (0)
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