Mary B. Kennedy
#118,937
Most Influential Person Now
American biochemist and neuroscientist
Mary B. Kennedy's AcademicInfluence.com Rankings
Mary B. Kennedybiology Degrees
Biology
#9268
World Rank
#12453
Historical Rank
#2413
USA Rank
Neuroscience
#1573
World Rank
#1624
Historical Rank
#249
USA Rank
Biochemistry
#1745
World Rank
#1880
Historical Rank
#287
USA Rank
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Biology
Mary B. Kennedy's Degrees
- Bachelors Biochemistry University of California, Berkeley
Why Is Mary B. Kennedy Influential?
(Suggest an Edit or Addition)According to Wikipedia, Mary Bernadette Kennedy is an American biochemist and neuroscientist. She is a member of the American Academy of Arts and Sciences, and is the Allen and Lenabelle Davis Professor of Biology at the California Institute of Technology, where she has been a member of the faculty since 1981. Her research focuses on the molecular mechanisms of synaptic plasticity, the process underlying formation of memory in the central nervous system. Her lab uses biochemical and molecular biological methods to study the protein machinery within a structure called the postsynaptic density. Kennedy has published over 100 papers with over 20,000 total citations.
Mary B. Kennedy's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95. (1995) (1879)
- Progressive development of the rat osteoblast phenotype in vitro: Reciprocal relationships in expression of genes associated with osteoblast proliferation and differentiation during formation of the bone extracellular matrix (1990) (1537)
- The rat brain postsynaptic density fraction contains a homolog of the drosophila discs-large tumor suppressor protein (1992) (1169)
- Regulation of brain Type II Ca 2+ calmodulin -dependent protein kinase by autophosphorylation: A Ca2+-triggered molecular switch (1986) (790)
- Signal-processing machines at the postsynaptic density. (2000) (765)
- Regional distribution of type II Ca2+/calmodulin-dependent protein kinase in rat brain (1985) (618)
- A Synaptic Ras-GTPase Activating Protein (p135 SynGAP) Inhibited by CaM Kinase II (1998) (571)
- Biochemical and immunochemical evidence that the "major postsynaptic density protein" is a subunit of a calmodulin-dependent protein kinase. (1983) (504)
- The postsynaptic density at glutamatergic synapses (1997) (497)
- Identification of Proteins in the Postsynaptic Density Fraction by Mass Spectrometry (2000) (405)
- Purification and characterization of a calmodulin-dependent protein kinase that is highly concentrated in brain. (1983) (397)
- Interaction of ion channels and receptors with PDZ domain proteins (1997) (374)
- Spine architecture and synaptic plasticity (2005) (362)
- Identification of a Phosphorylation Site for Calcium/Calmodulindependent Protein Kinase II in the NR2B Subunit of the N-Methyl-D-aspartate Receptor* (1996) (315)
- The major tyrosine-phosphorylated protein in the postsynaptic density fraction is N-methyl-D-aspartate receptor subunit 2B. (1994) (311)
- Tetanic Stimulation Leads to Increased Accumulation of Ca2+/Calmodulin-Dependent Protein Kinase II via Dendritic Protein Synthesis in Hippocampal Neurons (1999) (310)
- Regulation of neuronal function by calcium (1989) (307)
- Integration of biochemical signalling in spines (2005) (299)
- Distinct forebrain and cerebellar isozymes of type II Ca2+/calmodulin-dependent protein kinase associate differently with the postsynaptic density fraction. (1985) (287)
- Sequences of autophosphorylation sites in neuronal type II CaM kinase that control Ca2+-independent activity (1988) (258)
- Two calcium/calmodulin-dependent protein kinases, which are highly concentrated in brain, phosphorylate protein I at distinct sites. (1981) (252)
- Visualization of the Distribution of Autophosphorylated Calcium/Calmodulin-Dependent Protein Kinase II after Tetanic Stimulation in the CA1 Area of the Hippocampus (1997) (244)
- A calcium/calmodulin-dependent protein kinase from mammalian brain that phosphorylates Synapsin I: partial purification and characterization (1983) (209)
- C-Terminal Truncation of NR2A Subunits Impairs Synaptic But Not Extrasynaptic Localization of NMDA Receptors (2000) (205)
- Densin-180 Forms a Ternary Complex with the α-Subunit of Ca2+/Calmodulin-Dependent Protein Kinase II and α-Actinin (2001) (203)
- SynGAP Regulates Spine Formation (2004) (195)
- Signal transduction molecules at the glutamatergic postsynaptic membrane 1 Published on the World Wide Web on 24 October 1997. 1 (1998) (188)
- Deduced primary structure of the beta subunit of brain type II Ca2+/calmodulin-dependent protein kinase determined by molecular cloning. (1987) (186)
- Citron Binds to PSD-95 at Glutamatergic Synapses on Inhibitory Neurons in the Hippocampus (1999) (186)
- Interactions between the NR2B Receptor and CaMKII Modulate Synaptic Plasticity and Spatial Learning (2007) (177)
- Regulation of synaptic transmission in the central nervous system: Long-term potentiation (1989) (176)
- Characterization of Densin-180, a New Brain-Specific Synaptic Protein of the O-Sialoglycoprotein Family (1996) (166)
- Activation of type II calcium/calmodulin-dependent protein kinase by Ca2+/calmodulin is inhibited by autophosphorylation of threonine within the calmodulin-binding domain. (1990) (158)
- Immunoreactivity for a calmodulin-dependent protein kinase is selectively increased in macaque striate cortex after monocular deprivation. (1986) (133)
- Regulation of the Neuron-specific Ras GTPase-activating Protein, synGAP, by Ca2+/Calmodulin-dependent Protein Kinase II* (2004) (128)
- Ca2+/calmodulin-dependent protein kinase II (CaMKII) is activated by calmodulin with two bound calciums (2006) (125)
- Mammalian septins nomenclature. (2002) (125)
- SynGAP Regulates Steady-State and Activity-Dependent Phosphorylation of Cofilin (2008) (121)
- Synaptic Signaling in Learning and Memory. (2016) (110)
- Hippocampal Neurons Predisposed to Neurofibrillary Tangle Formation Are Enriched in Type II Calcium/Calmodulin-Dependent Protein Kinase (1990) (110)
- Conserved and variable regions in the subunits of brain type II Ca2+/calmodulin-dependent protein kinase (1988) (105)
- Hippocampal Synaptic Plasticity in Mice Overexpressing an Embryonic Subunit of the NMDA Receptor (1998) (104)
- Lysophosphatidyl choline facilitates labeling of CNS projections with horseradish peroxidase (1980) (103)
- Autophosphorylation of type II Ca2+/calmodulin-dependent protein kinase in cultures of postnatal rat hippocampal slices. (1991) (102)
- The postsynaptic density (1993) (99)
- Densin-180 forms a ternary complex with the (alpha)-subunit of Ca2+/calmodulin-dependent protein kinase II and (alpha)-actinin. (2001) (94)
- Tumor cells exhibit deregulation of the cell cycle histone gene promoter factor HiNF-D. (1990) (91)
- Experimental approaches to understanding the role of protein phosphorylation in the regulation of neuronal function. (1983) (82)
- Collective nomenclature for LAP proteins (2000) (82)
- The Huntington's disease mutation impairs Huntingtin's role in the transport of NF-κB from the synapse to the nucleus. (2010) (80)
- A Dynamic Model of Interactions of Ca2+, Calmodulin, and Catalytic Subunits of Ca2+/Calmodulin-Dependent Protein Kinase II (2010) (76)
- The α subunit of type II Ca2+/calmodulin-dependent protein kinase is highly conserved in Drosophila (1991) (68)
- Phosphorylation of Synaptic GTPase-activating Protein (synGAP) by Ca2+/Calmodulin-dependent Protein Kinase II (CaMKII) and Cyclin-dependent Kinase 5 (CDK5) Alters the Ratio of Its GAP Activity toward Ras and Rap GTPases* (2014) (68)
- Deletion of Densin-180 Results in Abnormal Behaviors Associated with Mental Illness and Reduces mGluR5 and DISC1 in the Postsynaptic Density Fraction (2011) (66)
- Structure and regulation of type II calcium/calmodulin-dependent protein kinase in central nervous system neurons. (1990) (66)
- Computational reconstitution of spine calcium transients from individual proteins (2015) (58)
- A role for synGAP in regulating neuronal apoptosis (2005) (57)
- A model for regulation by SynGAP-α1 of binding of synaptic proteins to PDZ-domain 'Slots' in the postsynaptic density (2016) (57)
- Structural Modeling of Protein Interactions by Analogy: Application to PSD-95 (2006) (47)
- Multi-state Modeling of Biomolecules (2014) (43)
- Detailed state model of CaMKII activation and autophosphorylation (2008) (42)
- The biochemistry of synaptic regulation in the central nervous system. (1994) (38)
- Autophosphorylation of type II CaM kinase in hippocampal neurons: localization of phospho- and dephosphokinase with complementary phosphorylation site-specific antibodies. (1993) (36)
- Presence of both constitutive and inducible forms of heat shock protein 70 in the cerebral cortex and hippocampal synapses. (2001) (34)
- Subcellular organization of camkii in rat hippocampal pyramidal neurons (2013) (29)
- Phosphorylation of smooth muscle myosin by type II Ca2+/calmodulin-dependent protein kinase (1990) (27)
- Densin-180 Controls the Trafficking and Signaling of L-Type Voltage-Gated Cav1.2 Ca2+ Channels at Excitatory Synapses (2017) (25)
- Telling tails (2001) (24)
- Molecular and behavioral changes associated with adult hippocampus-specific SynGAP1 knockout. (2012) (23)
- Sticking together. (2000) (22)
- Phosphorylation of synaptic GTPase-activating protein (synGAP) by polo-like kinase (Plk2) alters the ratio of its GAP activity toward HRas, Rap1 and Rap2 GTPases. (2018) (15)
- Interactions between calmodulin and neurogranin govern the dynamics of CaMKII as a leaky integrator (2019) (14)
- Chapter 3 – Calcium/Calmodulin-Dependent Protein Kinases (1987) (12)
- Visualization of autophosphorylation of Ca2+ calmodulin -dependent protein kinase II in hippocampal slices (1996) (11)
- PDZ affinity chromatography: a general method for affinity purification of proteins based on PDZ domains and their ligands. (2014) (9)
- The major tyrosine-phosphorylated protein in the postsynaptic density fraction is N-methyl-D-aspartate receptor subunit 2 B ( synapse / synaptic placty / sign rduction / glutamate receptor ) (2004) (9)
- Conserved and variable regions in the subunits of brain type II Ca2+/calmodulin-dependent protein kinase. (2008) (8)
- A sex difference in the response of the rodent postsynaptic density to synGAP haploinsufficiency (2019) (8)
- bound calciums /calmodulin-dependent protein kinase II (CaMKII) is activated by calmodulin with two 2+ Ca (2006) (7)
- The Protein Biochemistry of the Postsynaptic Density in Glutamatergic Synapses Mediates Learning in Neural Networks. (2018) (7)
- A multi-state model of the CaMKII dodecamer suggests a role for calmodulin in maintenance of autophosphorylation (2019) (7)
- Identification of Functionally Significant Phosphorylation Sites on Neuronal Proteins and Preparation of Antibodies That Recognize Them (1991) (7)
- On beyond LTP (1999) (6)
- Amplification of neurotoxic HTTex1 assemblies in human neurons (2021) (5)
- The Role of the Postsynaptic Density and the SpineCytoskeleton in Synaptic Plasticity (2008) (5)
- Characterization of calcium/calmodulin-dependent protein kinase II activity in the nervous system of the lobster,Panulirus interruptus (1998) (5)
- Do Activity‐Dependent Changes in Expression of Regulatory Proteins Play a Role in the Progression of Central Nervous System Neural Degeneration? (1989) (4)
- Correction: A model for regulation by SynGAP-α1 of binding of synaptic proteins to PDZ-domain 'Slots' in the postsynaptic density (2016) (4)
- The Huntington’s disease mutation impairs Huntingtin’s role in the transport of NF-kB from the synapse to the nucleus (2010) (4)
- Is Highly Conserved in Drosophila (1991) (4)
- Liquid Phase Transition in the Postsynaptic Density? (2017) (3)
- Protein Purification Using PDZ Affinity Chromatography (2015) (3)
- On beyond LTP. Long-term potentiation. (1999) (3)
- Type II CaS /calmodulin-dependent kinase phosphorylates tau protein in the region of the mouse repeat (1987) (3)
- The Synaptic Protein Network Associated with Ionotropic Glutamate Receptors (1999) (3)
- Deduced primary structure of the 13 subunit of brain type II Ca 2 + / calmodulin-dependent protein kinase determined by molecular cloning ( protein phosphorylation / synaptic regulation ) (2)
- Degenerative and protective signaling mechanisms in the neurofibrillary pathology of Alzheimer's disease (1995) (2)
- Biochemistry and neuroscience: the twain need to meet (2017) (2)
- Scaffold Proteins in the Postsynaptic Density (2008) (2)
- Calcium/Calmodulin-Dependent Protein Kinase II (2010) (2)
- Synaptic NMDA-Receptor Signaling Complex (2010) (1)
- Ca-CaM Protein Kinase 2 (2008) (1)
- Beautiful Transfer of Information (2001) (1)
- ANATOMICAL AND FUNCTIONAL MICRODOMAINS OF CALCIUM AND CALCIUM-DEPENDENT PROTEINS IN DENDRITIC SPINES (2001) (1)
- Multi-Stage Modeling of the Kinetics of Activation of CaMKII (2011) (1)
- New functions for synaptic vesicle proteins? (1985) (1)
- Forms a Ternary Complex with the a-Subunit of Ca 2 1 / Calmodulin-Dependent Protein Kinase II and a-Actinin (2001) (1)
- Response to “Problems with LAP nomenclature” (2001) (1)
- Review for "Functional implications of camkii alternative splicing" (2020) (0)
- Lysophosphatidyl choline facilitates labeling of central nervous system projections with horseradish peroxidase Methods (1980) (0)
- Organizing signal transduction in the postsynaptic density (2014) (0)
- Twocalcium/calmodulin-dependent protein kinases, whichare highly concentrated inbrain, phosphorylate protein I atdistinct sites (1981) (0)
- Modelling Ca2+ -dependent proteins in the spine - challenges and solutions (2012) (0)
- CHAPTER 90 – Calcium/Calmodulin-Dependent Protein Kinase II (2003) (0)
- A sex difference in the composition of the rodent postsynaptic density (2019) (0)
- CaMKII: CaM-dependent PK II (vertebrates) (Type II CaM-dependent PK, multifunctional CaM- dependent PK, CaM-dependent multiprotein kinase) (1995) (0)
- CHAPTER 178 – Synaptic NMDA-Receptor Signaling Complex (2003) (0)
- Decision letter: Control of protein synthesis and memory by GluN3A-NMDA receptors through inhibition of GIT1/mTORC1 assembly (2021) (0)
- Deduced primary structure of the f Ca2+/calmodulin-dependent protein molecular cloning (protein phosphorylation/synaptic regulation) (2016) (0)
- Decision letter: Alternative splicing at neuroligin site A regulates glycan interaction and synaptogenic activity (2020) (0)
- Biochemical and i unochemical evidence that the " major postsynaptic density protein " is a subunit of a calmodulin-dependent protein kinase ( synaptic structure / brain phosphoproteins / synaptic regulation ) (1999) (0)
- In memoriam: John Lisman – commentaries on CaMKII as a memory molecule (2018) (0)
- Competition in the postsynaptic density for PDZ domains of PSD-95 (2017) (0)
- DmCaMKII: Type II CaM-dependent PK (D. melanogaster) (Multifunctional CaM-dependent PK) (1995) (0)
- Coexistence of substance P and Ca++/calmodulin dependent protein kinase II in enteric neurons (1988) (0)
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