Mary C. Dinauer
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Philosophy Biology
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(Suggest an Edit or Addition)Mary C. Dinauer's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Mouse model of X–linked chronic granulomatous disease, an inherited defect in phagocyte superoxide production (1995) (918)
- Functional analysis of Nox4 reveals unique characteristics compared to other NADPH oxidases. (2006) (744)
- Deficiency of the hematopoietic cell-specific Rho family GTPase Rac2 is characterized by abnormalities in neutrophil function and host defense. (1999) (613)
- Salmonella pathogenicity island 2-dependent evasion of the phagocyte NADPH oxidase. (2000) (598)
- Phenotype of mice and macrophages deficient in both phagocyte oxidase and inducible nitric oxide synthase. (1999) (560)
- Activation of antibacterial autophagy by NADPH oxidases (2009) (525)
- A new genetic subgroup of chronic granulomatous disease with autosomal recessive mutations in p40 phox and selective defects in neutrophil NADPH oxidase activity. (2009) (394)
- Absence of Respiratory Burst in X-linked Chronic Granulomatous Disease Mice Leads to Abnormalities in Both Host Defense and Inflammatory Response to Aspergillus fumigatus (1997) (391)
- Periplasmic superoxide dismutase protects Salmonella from products of phagocyte NADPH-oxidase and nitric oxide synthase. (1997) (385)
- Dominant negative mutation of the hematopoietic-specific Rho GTPase, Rac2, is associated with a human phagocyte immunodeficiency. (2000) (369)
- The glycoprotein encoded by the X-linked chronic granulomatous disease locus is a component of the neutrophil cytochrome b complex (1987) (364)
- Ischemic stroke injury is reduced in mice lacking a functional NADPH oxidase. (1997) (359)
- Human neutrophil cytochrome b light chain (p22-phox). Gene structure, chromosomal location, and mutations in cytochrome-negative autosomal recessive chronic granulomatous disease. (1990) (338)
- Rac1 Deletion in Mouse Neutrophils Has Selective Effects on Neutrophil Functions1 (2003) (331)
- O2 sensing is preserved in mice lacking the gp91 phox subunit of NADPH oxidase. (1999) (286)
- Primary structure and unique expression of the 22-kilodalton light chain of human neutrophil cytochrome b. (1988) (285)
- Endothelial NADPH oxidase as the source of oxidants in lungs exposed to ischemia or high K+. (1998) (282)
- Germline CYBB mutations that selectively affect macrophages in kindreds with X-linked predisposition to tuberculous mycobacterial disease (2011) (236)
- Association of a Ras-related protein with cytochrome b of human neutrophils (1989) (225)
- Gene targeting of X chromosome-linked chronic granulomatous disease locus in a human myeloid leukemia cell line and rescue by expression of recombinant gp91phox. (1993) (222)
- Gp91(phox) is the heme binding subunit of the superoxide-generating NADPH oxidase. (1998) (218)
- Rac2 Is an Essential Regulator of Neutrophil Nicotinamide Adenine Dinucleotide Phosphate Oxidase Activation in Response to Specific Signaling Pathways1 (2001) (218)
- Autophagy proteins control goblet cell function by potentiating reactive oxygen species production (2013) (213)
- Partial Correction of the Phagocyte Defect in Patients with X-Linked Chronic Granulomatous Disease by Subcutaneous Interferon Gamma (1988) (202)
- NADPH oxidase is an O2 sensor in airway chemoreceptors: evidence from K+ current modulation in wild-type and oxidase-deficient mice. (2000) (196)
- Comparison of the roles of reactive oxygen and nitrogen intermediates in the host response to Mycobacterium tuberculosis using transgenic mice. (1997) (193)
- Library subtraction of in vitro cDNA libraries to identify differentially expressed genes in scrapie infection. (1990) (187)
- Mutations of the ELA2 gene found in patients with severe congenital neutropenia induce the unfolded protein response and cellular apoptosis. (2006) (186)
- NADPH-oxidase and a hydrogen peroxide-sensitive K+ channel may function as an oxygen sensor complex in airway chemoreceptors and small cell lung carcinoma cell lines. (1996) (180)
- X-Linked chronic granulomatous disease: mutations in the CYBB gene encoding the gp91-phox component of respiratory-burst oxidase. (1998) (179)
- Impaired superoxide production due to a deficiency in phagocyte NADPH oxidase fails to inhibit atherosclerosis in mice. (2000) (179)
- Processing and Maturation of Flavocytochromeb 558 Include Incorporation of Heme as a Prerequisite for Heterodimer Assembly* (2000) (172)
- Rac2 is critical for neutrophil primary granule exocytosis. (2004) (171)
- Chemoattractant-Stimulated Rac Activation in Wild-Type and Rac2-Deficient Murine Neutrophils: Preferential Activation of Rac2 and Rac2 Gene Dosage Effect on Neutrophil Functions1 (2002) (166)
- Absence of both the 91kD and 22kD subunits of human neutrophil cytochrome b in two genetic forms of chronic granulomatous disease. (1989) (164)
- Biosynthesis of the phagocyte NADPH oxidase cytochrome b558. Role of heme incorporation and heterodimer formation in maturation and stability of gp91phox and p22phox subunits. (1997) (161)
- Gene therapy of chronic granulomatous disease: the engraftment dilemma. (2011) (157)
- Regulation of neutrophil function by Rac GTPases (2003) (155)
- Regulation of the NADPH Oxidase and Associated Ion Fluxes During Phagocytosis (2013) (153)
- Role of NADPH Oxidase in the Mechanism of Lung Neutrophil Sequestration and Microvessel Injury Induced by Gram-Negative Sepsis: Studies in p47phox−/− and gp91phox−/− Mice1 (2002) (153)
- Mechanisms of NSAID-induced gastrointestinal injury defined using mutant mice. (2000) (152)
- The phosphoinositide-binding protein p40phox activates the NADPH oxidase during FcγIIA receptor–induced phagocytosis (2006) (152)
- Lupus-associated causal mutation in neutrophil cytosolic factor 2 (NCF2) brings unique insights to the structure and function of NADPH oxidase (2011) (147)
- A missense mutation in the neutrophil cytochrome b heavy chain in cytochrome-positive X-linked chronic granulomatous disease. (1989) (140)
- Relative contributions of myeloperoxidase and NADPH-oxidase to the early host defense against pulmonary infections with Candida albicans and Aspergillus fumigatus. (2002) (139)
- Rac2-Deficient Murine Macrophages Have Selective Defects in Superoxide Production and Phagocytosis of Opsonized Particles1 (2004) (134)
- Retroviral-mediated gene transfer of gp91phox into bone marrow cells rescues defect in host defense against Aspergillus fumigatus in murine X-linked chronic granulomatous disease. (1997) (131)
- Creation of a genetic system for analysis of the phagocyte respiratory burst: high-level reconstitution of the NADPH oxidase in a nonhematopoietic system. (2002) (128)
- Rac Activation Induces NADPH Oxidase Activity in Transgenic COS phox Cells, and the Level of Superoxide Production Is Exchange Factor-dependent* (2002) (124)
- Chronic granulomatous disease presenting in a 69-year-old man. (1991) (115)
- Glucose 6-Phosphate Dehydrogenase Is Required forSalmonella typhimurium Virulence and Resistance to Reactive Oxygen and Nitrogen Intermediates (1999) (110)
- Heme-ligating histidines in flavocytochrome b(558): identification of specific histidines in gp91(phox). (2001) (110)
- Cyclic 3',5'-AMP relay in Dictyostelium discoideum III. The relationship of cAMP synthesis and secretion during the cAMP signaling response (1980) (109)
- Cyclic 3', 5'-AMP relay dictyostelium discoideum. V. Adaptation of the cAMP signaling response during cAMP stimulation (1980) (108)
- Interferon-γ production by neutrophils during bacterial pneumonia in mice. (2011) (105)
- Mutational Analysis Reveals Distinct Features of the Nox4-p22phox Complex* (2008) (103)
- Fc gamma R-stimulated activation of the NADPH oxidase: phosphoinositide-binding protein p40phox regulates NADPH oxidase activity after enzyme assembly on the phagosome. (2008) (103)
- Cyclic 3', 5'-AMP relay in dictyostelium discoideum. IV. Recovery of the cAMP signaling response after adaptation to cAMP (1980) (99)
- Critical role of myeloperoxidase and nicotinamide adenine dinucleotide phosphate-oxidase in high-burden systemic infection of mice with Candida albicans. (2002) (99)
- Point mutation in the cytoplasmic domain of the neutrophil p22-phox cytochrome b subunit is associated with a nonfunctional NADPH oxidase and chronic granulomatous disease. (1991) (98)
- Molecular genetics of chronic granulomatous disease. (1988) (94)
- Antagonistic Cross-talk between Rac and Cdc42 GTPases Regulates Generation of Reactive Oxygen Species* (2004) (90)
- Neutrophil caveolin-1 expression contributes to mechanism of lung inflammation and injury. (2008) (89)
- Chronic granulomatous disease and other disorders of phagocyte function. (2005) (89)
- Cupric Yersiniabactin Is a Virulence-Associated Superoxide Dismutase Mimic (2013) (89)
- Mice lacking reduced nicotinamide adenine dinucleotide phosphate oxidase activity show increased susceptibility to early infection with Listeria monocytogenes. (1997) (87)
- The Hemopoietic Rho/Rac Guanine Nucleotide Exchange Factor Vav1 Regulates N-Formyl-Methionyl-Leucyl-Phenylalanine-Activated Neutrophil Functions 1 (2003) (85)
- Disorders of neutrophil function: an overview. (2007) (84)
- Rap1a Null Mice Have Altered Myeloid Cell Functions Suggesting Distinct Roles for the Closely Related Rap1a and 1b Proteins1 (2007) (84)
- Impaired Phagocytosis of Apoptotic Cells by Macrophages in Chronic Granulomatous Disease Is Reversed by IFN-γ in a Nitric Oxide-Dependent Manner (2010) (84)
- Somatic mutations and clonal hematopoiesis in congenital neutropenia. (2018) (83)
- Location of the Epitope for 7D5, a Monoclonal Antibody Raised against Human Flavocytochrome b558, to the Extracellular Peptide Portion of Primate gp91phox (2001) (82)
- Macrophage NADPH Oxidase Flavocytochrome b Localizes to the Plasma Membrane and Rab11-Positive Recycling Endosomes1 (2009) (81)
- Critical roles for p22phox in the structural maturation and subcellular targeting of Nox3. (2007) (80)
- Biosynthesis of flavocytochrome b558 . gp91(phox) is synthesized as a 65-kDa precursor (p65) in the endoplasmic reticulum. (1999) (79)
- Homeostatic Control of Innate Lung Inflammation by Vici Syndrome Gene Epg5 and Additional Autophagy Genes Promotes Influenza Pathogenesis. (2016) (79)
- Long-term correction of phagocyte NADPH oxidase activity by retroviral-mediated gene transfer in murine X-linked chronic granulomatous disease. (1999) (78)
- Phage display epitope mapping of human neutrophil flavocytochrome b558. Identification of two juxtaposed extracellular domains. (2001) (78)
- Inherited Neutrophil Disorders: Molecular Basis and New Therapies. (2000) (76)
- Partial correction of the phagocyte defect in patients with X-linked chronic granulomatous disease by subcutaneous interferon gamma. (1989) (73)
- Inherited p40phox deficiency differs from classic chronic granulomatous disease (2018) (72)
- Variable correction of host defense following gene transfer and bone marrow transplantation in murine X-linked chronic granulomatous disease. (2001) (71)
- p21-activated kinase (Pak) regulates NADPH oxidase activation in human neutrophils. (2005) (70)
- The gp91 phox Component of NADPH Oxidase Is Not the Voltage-gated Proton Channel in Phagocytes, but It Helps* (2001) (70)
- Genetic and cellular evidence of vascular inflammation in neurofibromin-deficient mice and humans. (2010) (69)
- Deletion Mutagenesis of p22phox Subunit of Flavocytochrome b558 (2006) (68)
- Antibody targeting KIT as pretransplantation conditioning in immunocompetent mice. (2010) (68)
- Preservation of complement-induced lung injury in mice with deficiency of NADPH oxidase. (1996) (68)
- Rac GTPase Isoform-specific Regulation of NADPH Oxidase and Chemotaxis in Murine Neutrophils in Vivo (2005) (68)
- Rac2 Regulates Neutrophil Chemotaxis, Superoxide Production, and Myeloid Colony Formation through Multiple Distinct Effector Pathways1 (2005) (66)
- The Rac Effector p67phox Regulates Phagocyte NADPH Oxidase by Stimulating Vav1 Guanine Nucleotide Exchange Activity (2006) (66)
- Primary Immune Deficiency Treatment Consortium (PIDTC) report. (2014) (64)
- Site-Specific Inhibitors of NADPH Oxidase Activity and Structural Probes of Flavocytochrome b: Characterization of Six Monoclonal Antibodies to the p22phox Subunit1 (2004) (64)
- Aspergillus fumigatus Copper Export Machinery and Reactive Oxygen Intermediate Defense Counter Host Copper-Mediated Oxidative Antimicrobial Offense. (2017) (62)
- p40phox: the last NADPH oxidase subunit. (2005) (61)
- Chronic granulomatous disease. (1992) (60)
- Are reactive oxygen species involved in the pathogenesis of murine cerebral malaria? (1999) (59)
- Mechanisms of interferon-γ production by neutrophils and its function during Streptococcus pneumoniae pneumonia. (2015) (59)
- A Critical Role of Protein Kinase Cδ Activation Loop Phosphorylation in Formyl-Methionyl-Leucyl-Phenylalanine-Induced Phosphorylation of p47phox and Rapid Activation of Nicotinamide Adenine Dinucleotide Phosphate Oxidase1 (2007) (59)
- Phagocyte-Derived Reactive Oxygen Species Do Not Influence the Progression of Murine Blood-Stage Malaria Infections (2005) (57)
- Neutrophil swarming delays the growth of clusters of pathogenic fungi (2020) (55)
- Restoration of phagocyte function by interferon-gamma in X-linked chronic granulomatous disease occurs at the level of a progenitor cell. (1990) (55)
- Phospholipase D2 (PLD2) is a guanine nucleotide exchange factor (GEF) for the GTPase Rac2 (2011) (54)
- High-level reconstitution of respiratory burst activity in a human X-linked chronic granulomatous disease (X-CGD) cell line and correction of murine X-CGD bone marrow cells by retroviral-mediated gene transfer of human gp91phox. (1996) (54)
- Restitution of superoxide generation in autosomal cytochrome-negative chronic granulomatous disease (A22(0) CGD)-derived B lymphocyte cell lines by transfection with p22phax cDNA (1993) (52)
- Correction of respiratory burst activity in X-linked chronic granulomatous cells to therapeutically relevant levels after gene transfer into bone marrow CD34+ cells. (1998) (51)
- Mutagenesis of an Arginine- and Lysine-rich Domain in the gp91 phox Subunit of the Phagocyte NADPH-oxidase Flavocytochromeb 558 * (1999) (50)
- The intracellular oxidation of 2',7'-dichlorofluorescin in murine T lymphocytes. (2001) (50)
- Absence of Proton Channels in COS-7 Cells Expressing Functional NADPH Oxidase Components (2002) (50)
- Reconstitution of Chemotactic Peptide-Induced Nicotinamide Adenine Dinucleotide Phosphate (Reduced) Oxidase Activation in Transgenic COS-phox Cells1 (2004) (48)
- The respiratory burst oxidase and the molecular genetics of chronic granulomatous disease. (1993) (48)
- An efferocytosis-induced, IL-4-dependent macrophage-iNKT cell circuit suppresses sterile inflammation and is defective in murine CGD. (2013) (48)
- The role of nicotinamide adenine dinucleotide phosphate oxidase-derived reactive oxygen species in the acquisition of metastatic ability of tumor cells. (2006) (48)
- Splice site mutations are a common cause of X-linked chronic granulomatous disease (1992) (46)
- Impaired NADPH oxidase activity in Rac2‐deficient murine neutrophils does not result from defective translocation of p47phox and p67phox and can be rescued by exogenous arachidonic acid (2006) (45)
- Primary immune deficiencies with defects in neutrophil function. (2016) (45)
- Gene therapy for chronic granulomatous disease (2004) (44)
- Variegation of retroviral vector gene expression in myeloid cells (2000) (44)
- p47phox Phox Homology Domain Regulates Plasma Membrane but Not Phagosome Neutrophil NADPH Oxidase Activation* (2010) (43)
- Rap1a null mice have altered myeloid cell functions suggesting distinct roles for the closely related Rap1a and 1b proteins (2008) (42)
- Functional analysis of NADPH oxidase in granulocytic cells expressing a delta488-497 gp91(phox) deletion mutant. (1999) (42)
- NADPH oxidase activation regulates apoptotic neutrophil clearance by murine macrophages. (2018) (42)
- Lethality of endotoxin in mice genetically deficient in the respiratory burst oxidase, inducible nitric oxide synthase, or both. (1999) (41)
- Cloning of murine gp91phox cDNA and functional expression in a human X-linked chronic granulomatous disease cell line. (1996) (41)
- Aspergillus fumigatus Copper Export Machinery and Reactive Oxygen Intermediate Defense Counter Host Copper-Mediated Oxidative Antimicrobial Offense. (2017) (41)
- Retrovirus-mediated reconstitution of respiratory burst activity in X-linked chronic granulomatous disease cells. (1994) (40)
- Cutting Edge: NADPH Oxidase Modulates MHC Class II Antigen Presentation by B Cells (2012) (40)
- Characterization of a Mutation in the Phox Homology Domain of the NADPH Oxidase Component p40phox Identifies A Mechanism for Negative Regulation of Superoxide Production* (2007) (39)
- A fluorescently tagged C-terminal fragment of p47phox detects NADPH oxidase dynamics during phagocytosis. (2009) (39)
- Phosphorylation of p22phox on Threonine 147 Enhances NADPH Oxidase Activity by Promoting p47phox Binding* (2009) (38)
- Gene therapy for chronic granulomatous disease. (2000) (37)
- Inflammatory consequences of inherited disorders affecting neutrophil function. (2019) (36)
- Identifying viral integration sites using SeqMap 2.0 (2011) (36)
- NADPH oxidase controls neutrophilic response to sterile inflammation in mice by regulating the IL-1α/G-CSF axis. (2015) (33)
- Suppressed hindlimb perfusion in Rac2-/- and Nox2-/- mice does not result from impaired collateral growth. (2009) (33)
- Disorders of neutrophil function: an overview. (2014) (33)
- Mutagenesis of p22 phox Histidine 94 (2002) (33)
- Haploinsufficiency of NADPH Oxidase Subunit Neutrophil Cytosolic Factor 2 Is Sufficient to Accelerate Full‐Blown Lupus in NZM 2328 Mice (2017) (33)
- Enhanced cutaneous inflammatory reactions to Aspergillus fumigatus in a murine model of chronic granulomatous disease. (2002) (33)
- SDF-1/CXCL12 enhances in vitro replating capacity of murine and human multipotential and macrophage progenitor cells. (2007) (32)
- Cloning of murine gp91phox cDNA and functional expression in a human X-linked chronic granulomatous disease cell line (1996) (32)
- Probing the Role of the Carboxyl Terminus of the gp91 phox Subunit of Neutrophil Flavocytochromeb 558 using Site-directed Mutagenesis* (1998) (30)
- Chronic granulomatous disease. Molecular genetics. (1988) (29)
- Lentivirus‐mediated gene transfer of gp91phox corrects chronic granulomatous disease (CGD) phenotype in human X‐CGD cells (2000) (28)
- The Dual Effect of Rac2 on Phospholipase D2 Regulation That Explains both the Onset and Termination of Chemotaxis (2011) (27)
- Aberrant Regulation of Hematopoiesis by T Cells in BAZF-Deficient Mice (2007) (27)
- Activation of neutrophil respiratory burst by fungal particles requires phosphatidylinositol 3-phosphate binding to p40(phox) in humans but not in mice. (2012) (27)
- Evidence for Two CRIB Domains in Phospholipase D2 (PLD2) That the Enzyme Uses to Specifically Bind to the Small GTPase Rac2* (2011) (26)
- Donor chimerism and stem cell function in a murine congenic transplantation model after low-dose radiation conditioning: effects of a retroviral-mediated gene transfer protocol and implications for gene therapy. (2002) (26)
- NADPH oxidase controls pulmonary neutrophil infiltration in the response to fungal cell walls by limiting LTB4. (2020) (24)
- From bench to bedside: preclinical evaluation of a self-inactivating gammaretroviral vector for the gene therapy of X-linked chronic granulomatous disease. (2013) (24)
- Gene Therapy for Chronic Granulomatous Disease (2003) (24)
- In vivo role of myeloperoxidase for the host defense. (2004) (22)
- Immunodeficiency and bone marrow failure with mosaic and germline TLR8 gain-of-function. (2020) (22)
- Myeloid Conditioning with c-kit-Targeted CAR-T Cells Enables Donor Stem Cell Engraftment. (2018) (22)
- Characterization of P-Rex1 for its role in fMet-Leu-Phe-induced superoxide production in reconstituted COS(phox) cells. (2010) (21)
- Long-term high-level reconstitution of NADPH oxidase activity in murine X-linked chronic granulomatous disease using a bicistronic vector expressing gp91phox and a Delta LNGFR cell surface marker. (2003) (20)
- Biosynthesis of the Phagocyte NADPH Oxidase Cytochrome b 558 ROLE OF HEME INCORPORATION AND HETERODIMER FORMATION IN MATURATION AND STABILITY OF gp 91 (1997) (20)
- A murine model of antimetabolite-based, submyeloablative conditioning for bone marrow transplantation: biologic insights and potential applications. (2004) (19)
- Splice site mutations are a common cause of X-linked chronic granulomatous disease. (1992) (19)
- PI(3)P‐p40phox binding regulates NADPH oxidase activation in mouse macrophages and magnitude of inflammatory responses in vivo (2017) (18)
- Newly diagnosed chronic granulomatous disease in a 53-year-old woman with Crohn disease. (2005) (17)
- Phage Display Epitope Mapping of Human Neutrophil Flavocytochromeb 558 (2001) (17)
- Biosynthesis of the Phagocyte NADPH Oxidase Cytochromeb 558 (1997) (16)
- Granulocyte Colony‐Stimulating Factor Prior to Nonmyeloablative Irradiation Decreases Murine Host Hematopoietic Stem Cell Function and Increases Engraftment of Donor Marrow Cells (2007) (14)
- Retroviral-mediated gene transfer and nonmyeloablative conditioning: studies in a murine X-linked chronic granulomatous disease model. (2002) (14)
- Stable long-term gene correction with low-dose radiation conditioning in murine X-linked chronic granulomatous disease. (2004) (13)
- Automated analysis of viral integration sites in gene therapy research using the SeqMap web resource (2008) (13)
- Neutrophil Functions-Formyl-Methionyl-Leucyl-Phenylalanine-Act N Nucleotide Exchange Factor Vav 1 Regulates The Hemopoietic Rho / Rac Guanine (2003) (13)
- The role of Rac2 in regulating neutrophil production in the bone marrow and circulating neutrophil counts. (2008) (12)
- Retroviral vector integration in post-transplant hematopoiesis in mice conditioned with either submyeloablative or ablative irradiation (2009) (12)
- Chronic granulomatous disease and glutathione peroxidase deficiency, revisited. (1994) (12)
- Gene correction reduces cutaneous inflammation and granuloma formation in murine X-linked chronic granulomatous disease. (2005) (12)
- A sustained type I IFN-neutrophil-IL-18 axis drives pathology during mucosal viral infection (2020) (11)
- Mitochondrial transmembrane potential is diminished in phorbol myristate acetate-stimulated peritoneal resident macrophages isolated from wild-type mice, but not in those from gp91-phox-deficient mice (2004) (11)
- Rac2 Concentrations in Umbilical Cord Neutrophils (2006) (11)
- Interferon-? and chronic granulomatous disease (1991) (11)
- Identification and functional characterization of the murine Rac2 gene promoter. (1999) (11)
- Hematologically important mutations: X-linked chronic granulomatous disease (fourth update). (2021) (10)
- Two CGD Families with a Hypomorphic Mutation in the Activation Domain of p67phox. (2014) (10)
- PHILADELPHIA CHROMOSOME BY TRANSLOCATION (1973) (9)
- Targeted inhibition of the small GTPase protects against ischemia/reperfusion liver injury in mice. (2001) (8)
- Point mutation in the cytoplasmic domain of the neutrophil p 22-phox cytochrome b subunit is associated with a nonfunctional NADPH oxidase and chronic granulomatous disease ( respiratory burst / superoxide / phagocyte / polymerase chain reaction ) (7)
- Monoclonal antibody CL5 recognizes the amino terminal domain of human phagocyte flavocytochrome b558 large subunit, gp91phox (2005) (6)
- LysMD3 is a type II membrane protein without an in vivo role in the response to a range of pathogens (2018) (6)
- Inherited Neutrophil Disorders (2000) (6)
- Neutrophil Defects and Diagnosis Disorders of Neutrophil Function: An Overview. (2020) (6)
- Neutrophil DREAM promotes neutrophil recruitment in vascular inflammation (2021) (6)
- Heme-ligating Histidines in Flavocytochromeb 558 (2001) (6)
- Heme-ligating Histidines in Flavocytochrome b558 IDENTIFICATION OF SPECIFIC HISTIDINES IN gp91* (2001) (6)
- X-Linked Chronic Granulomatous Disease (2010) (5)
- Critical roles for p 22 phox in the structural maturation and subcellular targeting of Nox 3 (2007) (5)
- The C‐terminal flavin domain of gp91phox bound to plasma membranes of granulocyte‐like X‐CGD PLB‐985 cells is sufficient to anchor cytosolic oxidase components and support NADPH oxidase‐associated diaphorase activity independent of cytosolic phospholipase A2 regulation (2006) (5)
- Biosynthesis of Flavocytochrome b 558 (1999) (5)
- Interferon-gamma and chronic granulomatous disease. (1991) (4)
- Enhanced Expression of CXCR4 Facilitates C-Kit-Targeted CAR-T Cell Trafficking to Bone Marrow and Enables Donor Stem Cell Engraftment (2018) (4)
- Absence of Both the 9 lkD and 22 kD Subunits of Human Neutrophil Cytochrome b in Two Genetic Forms of Chronic Granulomatous Disease (2005) (4)
- Insights into the NOX NADPH Oxidases Using Heterologous Whole Cell Assays. (2019) (4)
- Macrophage NOX2 NADPH oxidase maintains alveolar homeostasis in mice. (2022) (4)
- NADPH Oxidase Limits Collaborative Pattern-Recognition Receptor Signaling to Regulate Neutrophil Cytokine Production in Response to Fungal Pathogen-Associated Molecular Patterns (2021) (4)
- Phagocytosis of Opsonized Particles Selective Defects in Superoxide Production Rac 2-Deficient Murine Macrophages Have (2004) (4)
- Leukocyte function and nonmalignant leukocyte disorders (1993) (3)
- Vav1 inhibits RANKL-induced osteoclast differentiation and bone resorption (2019) (3)
- P-21 activated kinase (Pak) regulates NADPH oxidase activation in human neutrophils Pak regulates phagocyte NADPH oxidase (2005) (3)
- Evidence for the involvement of the NADPH oxidase enzyme complex in the optimal accumulation of Platelet-activating factor in the human cell line PLB-985. (2001) (3)
- [Expression and activity of polymorphisms in the 67-kDa protein of the NADPH oxidase system]. (2004) (3)
- Role for p40 phox in Fcγ-Receptor-Induced NADPH Oxidase Activation. (2004) (3)
- Chapter 50 – Disorders of Phagocyte Function (2017) (2)
- Activation in Transgenic COS-phox Cells Dinucleotide Phosphate ( Reduced ) Oxidase Peptide-Induced Nicotinamide Adenine Reconstitution of Chemotactic (2004) (2)
- Donor chimerism and gene correction with low dose irradiation and retroviral-mediated gene transfer (Rmgt) In murine x-linked chronic granulomatous disease (X-cgd) (2000) (2)
- The Phosphoinositide-Binding Protein p40phox Regulates NADPH Oxidase Activation Rather Than Assembly during FcγIIA Receptor-Induced Phagocytosis. (2006) (2)
- NADPH oxidase 2 limits amplification of IL-1β–G-CSF axis and an immature neutrophil subset in murine lung inflammation (2022) (2)
- The size of the guanosine triphosphate pool active in the synthesis of stable RNA by stage 6 oocytes of Xenopus laevis. (1976) (2)
- CHARACTERIZATION OF A MUTATION IN THE PX DOMAIN OF THE NADPH OXIDASE COMPONENT p 40 PHOX IDENTIFIES A MECHANISM FOR NEGATIVE REGULATION OF SUPEROXIDE PRODUCTION * (2007) (2)
- Gene therapy for chronic granulomatous disease and leukocyte adhesion deficiency (2001) (2)
- PHAGOCYTES , GRANULOCYTES , AND MYELOPOIESIS An efferocytosis-induced , IL-4 – dependent macrophage-iNKT cell circuit suppresses sterile in fl ammation and is defective in murine CGD (2013) (1)
- Derivation of extra-embryonic and intra-embryonic macrophage lineages from human pluripotent stem cells. (2022) (1)
- Pathways Formation through Multiple Distinct Effector Superoxide Production , and Myeloid Colony Rac 2 Regulates Neutrophil Chemotaxis (2005) (1)
- Efferocytosis induces macrophages to produce IL-4 and activate invariant NKT cells to suppress inflammation (117.17) (2012) (1)
- Neutrophil and Macrophage NADPH Oxidase 2 Differentially Control Responses to Inflammation and to Aspergillus fumigatus in Mice (2022) (1)
- cytochrome b in two genetic forms of chronic granulomatous disease Absence of both the 91kD and 22kD subunits of human neutrophil (2011) (1)
- Analysis of a p67 phox Δ401 Mutant Identified in Chronic Granulomatous Disease: Deletion of C-Terminal SH3 Binding Site for p47 phox Still Supports NADPH Oxidase Activity in Cosphox Cells. (2004) (1)
- Use of paired dose 5-fluorouracil as a conditioning regimen for marrow transplantation in a syngeneic mouse model. w (2000) (1)
- Development and Evaluation of Quality Metrics for Bioinformatics Analysis of Viral Insertion Site Data Generated Using High Throughput Sequencing (2014) (1)
- activity after enzyme assembly on the phagosome phosphoinositide-binding protein p40phox regulates NADPH oxidase R-stimulated activation of the NADPH oxidase: γ Fc (2013) (1)
- Granulocytic Precursors from Patients with ELA2-Mutant Severe Congenital Neutropenia Display a Transcriptional Profile Consistent with Activation of the Unfolded Protein Response. (2007) (0)
- gene transfer of human gp91phox correction of murine X-CGD bone marrow cells by retroviral-mediated linked chronic granulomatous disease (X-CGD) cell line and High-level reconstitution of respiratory burst activity in a human X- (2011) (0)
- Biased Engraftment of Retrovirus-Transduced Marrow in Murine X-CGD Following Submyeloablative Conditioning. (2006) (0)
- Neutrophil chemotaxis: a tail of 2 GTPases (2006) (0)
- p47 phox PX domain regulates plasma membrane but not phagosome neutrophil NADPH oxidase activation (2010) (0)
- Arachidonic Acid Rescues Defects on PMA-Elicited NADPH Oxidase Activity in Rac2-Deficient Neutrophils. (2004) (0)
- granulomatous disease Splice site mutations are a common cause of X-linked chronic (2011) (0)
- neutrophils P-21 activated kinase (Pak) regulates NADPH oxidase activation in human (2013) (0)
- X-linked Chronic Granulomatous Disease Presenting with Mediastinal Lipoblastoma and Adjacent Pneumonia (2021) (0)
- 39 Fluorescently Tagged Proteins to Monitor NADPH Oxidase Assembly During Phagocytosis (2006) (0)
- Laurence Alan Boxer, M.D. (1940–2017) (2017) (0)
- Transport Adequacy (1999) (0)
- Publisher Correction: Neutrophil swarming delays the growth of clusters of pathogenic fungi (2020) (0)
- activity after enzyme assembly on the phagosome regulates NADPH oxidase phox phosphoinositide-binding protein p 40 R-stimulated activation of the NADPH oxidase : (2008) (0)
- CellsMHC Class II Antigen Presentation by B Cutting Edge: NADPH Oxidase Modulates (2012) (0)
- Supplemental Figure 4-Nox2 Collaterals & Gastroc after Excision (2013) (0)
- Developing a clinically applicable protocol for gene transfer using retroviral infection on fibronectin (1997) (0)
- NADPH Oxidase Controls Neutrophil Infiltration in the Lung in Early Response to Fungal Cell Walls Via LTB4 (2019) (0)
- neutrophil NADPH oxidase activity and selective defects in phox autosomal recessive mutations in p 40 A new genetic subgroup of chronic granulomatous disease with (2009) (0)
- DEFICIENCY OF PHAGOCYTE OXIDASE CONFERS NO SURVIVAL BENEFIT IN A MOUSE MODEL OF SEPTIC SHOCK.: 80 (1998) (0)
- Granulocyte Colony-Stimulating Factor Prior to Low-Dose Total Body Irradiation as Conditioning Regimen in Hematopoietic Stem Cell Transplantation for Gene Therapy. (2004) (0)
- phox Monoclonal Antibodies to the p22 : Characterization of Six b Flavocytochrome Activity and Structural Probes of Site-Specific Inhibitors of NADPH Oxidase (2004) (0)
- Characterization of the novel molecule LysMD 3 1 LysMD 3 is a type II membrane protein without an in vivo role in the response to a range of pathogens (2018) (0)
- Role for NADPH oxidase in macrophage clearance of apoptotic cells (2011) (0)
- Gram-Negative Sepsis: Studies in p47 Microvessel Injury Induced by Lung Neutrophil Sequestration and Role of NADPH Oxidase in the Mechanism of (2002) (0)
- Specific Signaling Pathways Phosphate Oxidase Activation in Response to Nicotinamide Adenine Dinucleotide Rac 2 Is an Essential Regulator of Neutrophil (2000) (0)
- Granulomatous Disease Retroviral-Mediated Gene Transfer in Murine X-Linked Chronic Long-Term Correction of Phagocyte NADPH Oxidase Activity by (2013) (0)
- Faculty Opinions recommendation of CFTR regulates phagosome acidification in macrophages and alters bactericidal activity. (2006) (0)
- Correction: The hemopoietic Rho/Rac guanine nucleotide exchange factor Vav1 regulates N-formyl-methionyl-leucyl-phenylalanine-activated neutrophil functions (2013) (0)
- Sa.111. Chronic Granulomatous Disease (CGD) Presenting with Eosinophilia and CD3 Lymphopenia (2006) (0)
- A Novel CYBB Variant Causing X-Linked Chronic Granulomatous Disease in a Patient with Empyema (2020) (0)
- Rac2 is expressed by pulmonary endothelial cells (2007) (0)
- Polymorphonuclear Leukocytes Increase Mesothelial Cell Monolayer Permeability by Oxygen Radical Independent Mechanisms (1999) (0)
- A Novel CYBB Variant Causing X-Linked Chronic Granulomatous Disease in a Patient with Empyema (2020) (0)
- Selective Effects on Neutrophil Functions Rac1 Deletion in Mouse Neutrophils Has (2003) (0)
- NADPH Oxidase Limits Sterile Inflammation By Modulating IL-1/G-CSF-Driven Neutrophilic Inflammation (2014) (0)
- Faculty Opinions recommendation of Activation of the superoxide-producing phagocyte NADPH oxidase requires co-operation between the tandem SH3 domains of p47phox in recognition of a polyproline type II helix and an adjacent alpha-helix of p22phox. (2006) (0)
- Role of NADPH Oxidase in the Mechanism of Lung Neutrophil Sequestration and Microvessel Injury Induced by Gram-Negative Sepsis: Studies in p47 (2002) (0)
- Development of Conditioning Regimens Based on HSC-Targeted Antibody ACK2 (2014) (0)
- Editorial overview: Viral methods for gene transfer (1999) (0)
- Supplemental Figure 2-Bl6 & Rac2 Gastroc after Ligation (2013) (0)
- Oxide-Dependent Manner in a Nitric g Disease Is Reversed by IFN-Macrophages in Chronic Granulomatous Impaired Phagocytosis of Apoptotic Cells by (2010) (0)
- Faculty Opinions recommendation of Superoxide production at phagosomal cup/phagosome through beta I protein kinase C during Fc gamma R-mediated phagocytosis in microglia. (2004) (0)
- The Rho-related GTPase Rac2 is essential for regulation of neutrophil azurophilic granule release (2003) (0)
- Reconstitution of Neutrophil NADPH Oxidase Activity in Murine X-CGD Following Transplantation of Retrovirus-Transduced Marrow: Potential Impact of Submyeloablative Conditioning. (2005) (0)
- Letter: Philadelphia chromosome by translocation. (1973) (0)
- Selection for gp91phox-transduced murine hematopoietic progenitors by mutant mgmt (P140K) mediated resistance to BG and BCNU using a bicistronic retroviral vector (2000) (0)
- CELLULAR THERAPY AND HEMATOPOIETIC STEM CELL TRANSPLANTATION FOR CANCER (2010) (0)
- Rac2, is associated with a human phagocyte immunodeficiency Dominant negative mutation of the hematopoietic-specific Rho GTPase, (2011) (0)
- Faculty Opinions recommendation of HAX1 deficiency causes autosomal recessive severe congenital neutropenia (Kostmann disease). (2007) (0)
- Issue Information (2011) (0)
- Supplemental Figure 1-Models-Ligation & Excision (2013) (0)
- Neutrophil swarming delays the growth of clusters of pathogenic fungi (2020) (0)
- Supplemental Legends and Tables (2013) (0)
- Role for NADPH oxidase in macrophage clearance of apoptotic cells (54.2) (2011) (0)
- Publisher Correction: Neutrophil swarming delays the growth of clusters of pathogenic fungi (2020) (0)
- Acknowledgement to the Reviewers (2020) (0)
- Supplemental Figure 3-Bl6 & Rac2 Gastroc after Excision (2013) (0)
- NADPH oxidase flavocytochrome b localizes to Rab11‐positive recycling endosomes in macrophages (2008) (0)
- INHIBITION OF THE SMALL GTPase, RAC1, PROTECTS AGAINST POST‐ISCHEMIC LIVER INJURY BY SUPPRESSING GENERATION OF INTRACELLULAR REACTIVE OXYGEN SPECIES AND NF‐kB BINDING ACTIVITY.: Abstract# 1011 (2000) (0)
- NOX2 NADPH oxidase controls responses to infection and sterile inflammation (2018) (0)
- Neutrophil and Macrophage NADPH Oxidase 2 Differentially Control Responses to Inflammation and to Aspergillus fumigatus in Mice. (2022) (0)
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What Schools Are Affiliated With Mary C. Dinauer?
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