Mary Collins
British immunologist
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Biology
Mary Collins 's Degrees
- Bachelors Biology University of Oxford
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(Suggest an Edit or Addition)According to Wikipedia, Mary Katharine Levinge Collins, Lady Hunt is a British Professor of virology and the director of the Queen Mary University of London Blizard Institute. She served as Provost at the Okinawa Institute of Science and Technology in Japan. Formerly, Collins taught in the Division of Infection and Immunity at University College London, and was the head of the Division of Advanced Therapies at the National Institute for Biological Standards and Control, and the Director of the Medical Research Council Centre for Medical Molecular Virology. Her research group studies the use of viruses as vectors for introducing new genes into cells, which can be useful for experimental cell biology, for clinical applications such as gene therapy, and as cancer vaccines.
Mary Collins 's Published Works
Published Works
- Engagement of the Pd-1 Immunoinhibitory Receptor by a Novel B7 Family Member Leads to Negative Regulation of Lymphocyte Activation (2000) (4505)
- Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides (2006) (2296)
- CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor. (2002) (1609)
- The B7 family of ligands and its receptors: new pathways for costimulation and inhibition of immune responses. (2002) (938)
- High-titer packaging cells producing recombinant retroviruses resistant to human serum (1995) (706)
- PD‐1:PD‐L inhibitory pathway affects both CD4+ and CD8+ T cells and is overcome by IL‐2 (2002) (678)
- IL-13, IL-4Ralpha, and Stat6 are required for the expulsion of the gastrointestinal nematode parasite Nippostrongylus brasiliensis. (1998) (662)
- IL-22 is required for Th17 cell-mediated pathology in a mouse model of psoriasis-like skin inflammation. (2008) (553)
- Engagement of Glucocorticoid-Induced TNFR Family-Related Receptor on Effector T Cells by its Ligand Mediates Resistance to Suppression by CD4+CD25+ T Cells (2004) (524)
- IL-21 limits NK cell responses and promotes antigen-specific T cell activation: a mediator of the transition from innate to adaptive immunity. (2002) (513)
- Mouse Inducible Costimulatory Molecule (ICOS) Expression Is Enhanced by CD28 Costimulation and Regulates Differentiation of CD4+ T Cells1 (2000) (495)
- An IL-17F/A Heterodimer Protein Is Produced by Mouse Th17 Cells and Induces Airway Neutrophil Recruitment (2007) (371)
- Inter-regulation of Th17 cytokines and the IL-36 cytokines in vitro and in vivo: implications in psoriasis pathogenesis. (2011) (357)
- The murine IL-13 receptor alpha 2: molecular cloning, characterization, and comparison with murine IL-13 receptor alpha 1. (1998) (345)
- The IL-21 receptor augments Th2 effector function and alternative macrophage activation. (2006) (341)
- Identification of an Interleukin 17F/17A Heterodimer in Activated Human CD4+ T Cells* (2007) (322)
- IL-21 Has a Pathogenic Role in a Lupus-Prone Mouse Model and Its Blockade with IL-21R.Fc Reduces Disease Progression (2007) (315)
- Interleukin 21 Is a T Helper (Th) Cell 2 Cytokine that Specifically Inhibits the Differentiation of Naive Th Cells into Interferon γ–producing Th1 Cells (2002) (302)
- Blockade of the interleukin-21/interleukin-21 receptor pathway ameliorates disease in animal models of rheumatoid arthritis. (2007) (298)
- Program Death-1 Engagement Upon TCR Activation Has Distinct Effects on Costimulation and Cytokine-Driven Proliferation: Attenuation of ICOS, IL-4, and IL-21, But Not CD28, IL-7, and IL-15 Responses (2003) (286)
- Utility of animal models for identification of potential therapeutics for rheumatoid arthritis (2007) (284)
- The Human IL-17F/IL-17A Heterodimeric Cytokine Signals through the IL-17RA/IL-17RC Receptor Complex (2008) (272)
- Regulation and Function of the Interleukin 13 Receptor α 2 During a T Helper Cell Type 2–dominant Immune Response (2003) (269)
- The B7 family of immune-regulatory ligands (2005) (265)
- Type C retrovirus inactivation by human complement is determined by both the viral genome and the producer cell (1994) (250)
- Sensitization of cells and retroviruses to human serum by (αl-3) galactosyltransferase (1996) (248)
- Retroviral retargeting by envelopes expressing an N-terminal binding domain (1995) (241)
- Th17 cytokines and their emerging roles in inflammation and autoimmunity (2008) (227)
- Activation of antigen-presenting cells by microbial products breaks self tolerance and induces autoimmune disease. (2004) (223)
- PD-L1 co-stimulation contributes to ligand-induced T cell receptor down-modulation on CD8+ T cells (2011) (213)
- IL-21 Induces the Apoptosis of Resting and Activated Primary B Cells1 (2003) (203)
- Expression of the bacterial nitroreductase enzyme in mammalian cells renders them selectively sensitive to killing by the prodrug CB1954. (1995) (201)
- Enhanced Interleukin (IL)-13 Responses in Mice Lacking IL-13 Receptor α 2 (2003) (191)
- IL-21 Activates Both Innate and Adaptive Immunity to Generate Potent Antitumor Responses that Require Perforin but Are Independent of IFN-γ1 (2003) (189)
- Continuous high-titer HIV-1 vector production (2003) (184)
- Prevention and treatment of factor VIII inhibitors in murine hemophilia A. (2000) (184)
- Stable gene transfer to muscle using non-integrating lentiviral vectors. (2007) (181)
- PD-1/PD-L1, but not PD-1/PD-L2, interactions regulate the severity of experimental autoimmune encephalomyelitis (2007) (173)
- Fulminant spontaneous autoimmunity of the central nervous system in mice transgenic for the myelin proteolipid protein-specific T cell receptor. (2000) (169)
- Duplication of primate and rodent B7-H3 immunoglobulin V- and C-like domains: divergent history of functional redundancy and exon loss. (2003) (165)
- IL-22 Induces an Acute-Phase Response (2010) (160)
- Feline leukemia virus subgroup B uses the same cell surface receptor as gibbon ape leukemia virus (1992) (157)
- Specific T Regulatory Cells Display Broad Suppressive Functions against Experimental Allergic Encephalomyelitis upon Activation with Cognate Antigen1 (2005) (142)
- IL-4, IL-10, IL-13, and TGF-β from an Altered Peptide Ligand-Specific Th2 Cell Clone Down-Regulate Adoptive Transfer of Experimental Autoimmune Encephalomyelitis (2000) (139)
- Insertional Gene Activation by Lentiviral and Gammaretroviral Vectors (2008) (137)
- HIV-1 Lentiviral Vector Immunogenicity Is Mediated by Toll-Like Receptor 3 (TLR3) and TLR7 (2010) (133)
- The bystander effect of the nitroreductase/CB1954 enzyme/prodrug system is due to a cell-permeable metabolite. (1997) (132)
- Targeting dendritic cell signaling to regulate the response to immunization. (2008) (130)
- Gene therapy: progress and predictions (2015) (130)
- Tumor necrosis factor alpha blockade exacerbates murine psoriasis-like disease by enhancing Th17 function and decreasing expansion of Treg cells. (2010) (127)
- Postentry Restriction to Human Immunodeficiency Virus-Based Vector Transduction in Human Monocytes (2001) (126)
- Redundant and Pathogenic Roles for IL-22 in Mycobacterial, Protozoan, and Helminth Infections (2010) (125)
- Intravenous Injection of a Lentiviral Vector Encoding NY-ESO-1 Induces an Effective CTL Response1 (2004) (123)
- IL-21 effects on human IgE production in response to IL-4 or IL-13. (2004) (119)
- Sensitization of cells and retroviruses to human serum by (alpha 1-3) galactosyltransferase. (1996) (113)
- Immunization with a lentiviral vector stimulates both CD4 and CD8 T cell responses to an ovalbumin transgene. (2006) (112)
- The JNK-interacting Protein-1 Scaffold Protein Targets MAPK Phosphatase-7 to Dephosphorylate JNK* (2003) (110)
- Tubulovesicular Structures within Vesicular Stomatitis Virus G Protein-Pseudotyped Lentiviral Vector Preparations Carry DNA and Stimulate Antiviral Responses via Toll-Like Receptor 9 (2006) (103)
- Inhibition of CTLA-4 Function by the Regulatory Subunit of Serine/Threonine Phosphatase 2A1 (2002) (99)
- Heteroclitic proliferative responses and changes in cytokine profile induced by altered peptides: implications for autoimmunity. (1998) (94)
- BTLA: a new inhibitory receptor with a B7-like ligand. (2003) (93)
- Nonintegrating Lentivector Vaccines Stimulate Prolonged T-Cell and Antibody Responses and Are Effective in Tumor Therapy (2009) (90)
- Paradoxical inhibition of T-cell function in response to CTLA-4 blockade; heterogeneity within the human T-cell population (2000) (86)
- Construction of stable packaging cell lines for clinical lentiviral vector production (2015) (86)
- Immunization with a Lentivector That Targets Tumor Antigen Expression to Dendritic Cells Induces Potent CD8+ and CD4+ T-Cell Responses (2007) (85)
- IL-21 Receptor Is Required for the Systemic Accumulation of Activated B and T Lymphocytes in MRL/MpJ-Faslpr/lpr/J Mice (2012) (84)
- IL-21R is essential for epicutaneous sensitization and allergic skin inflammation in humans and mice. (2008) (84)
- Abrogation of Ref1 Retrovirus Restriction in Human Cells (2002) (83)
- Complete sequence determination of the mouse and human CTLA4 gene loci: cross-species DNA sequence similarity beyond exon borders. (1999) (81)
- Blockade of T Cell Activation Using a Surface-Linked Single-Chain Antibody to CTLA-4 (CD152)1 (2000) (79)
- Selective functional inhibition of JAK-3 is sufficient for efficacy in collagen-induced arthritis in mice. (2010) (74)
- Mutation of amino acids within the gibbon ape leukemia virus (GALV) receptor differentially affects feline leukemia virus subgroup B, simian sarcoma-associated virus, and GALV infections (1993) (74)
- IL‐21 Modulates CD4+ CD25+ Regulatory T‐Cell Homeostasis in Experimental Autoimmune Encephalomyelitis (2007) (70)
- Effector T cell differentiation: are master regulators of effector T cells still the masters? (2015) (69)
- Selective ERK Activation Differentiates Mouse and Human Tolerogenic Dendritic Cells, Expands Antigen-Specific Regulatory T Cells, and Suppresses Experimental Inflammatory Arthritis (2011) (68)
- IL-21 Receptor Is Critical for the Development of Memory B Cell Responses (2011) (67)
- Immunomodulatory effects in mice of polyinosinic-polycytidylic acid complexed with poly-L-lysine and carboxymethylcellulose. (1985) (65)
- Retrovirus Targeting by Tropism Restriction to Melanoma Cells (1999) (64)
- Assembly and annotation of human chromosome 2q33 sequence containing the CD28, CTLA4, and ICOS gene cluster: analysis by computational, comparative, and microarray approaches. (2001) (62)
- DNA vaccines encoding retrovirus-based virus-like particles induce efficient immune responses without adjuvant. (2006) (62)
- Efficient retroviral infection of mammalian cells is blocked by inhibition of poly(ADP-ribose) polymerase activity (1996) (61)
- Cationic Liposomes Enhance the Rate of Transduction by a Recombinant Retroviral Vector In Vitro and In Vivo (1998) (59)
- Dynamic Interaction between the Dual Specificity Phosphatase MKP7 and the JNK3 Scaffold Protein β-Arrestin 2* (2005) (59)
- IL-21 and IL-21 receptor (2003) (58)
- Suppressor T cells: some answers but more questions. (1992) (57)
- Retroviral vector targeting to melanoma cells by single-chain antibody incorporation in envelope. (1998) (57)
- IL-22R, IL-10R2, and IL-22BP binding sites are topologically juxtaposed on adjacent and overlapping surfaces of IL-22. (2008) (53)
- The Murine IL-13 Receptor α2: Molecular Cloning, Characterization, and Comparison with Murine IL-13 Receptor α1 (1998) (52)
- Autoreactive T Cells Mediate NK Cell Degeneration in Autoimmune Disease1 (2006) (52)
- Lentiviral vectors transduce proliferating dendritic cell precursors leading to persistent antigen presentation and immunization. (2009) (52)
- Augmentation of NK cell activity in tissue specific sites by liposomes incorporating MTP-PE. (1985) (50)
- Gene transfer to repopulating human CD34+ cells using amphotropic-, GALV-, or RD114-pseudotyped HIV-1-based vectors from stable producer cells. (2005) (49)
- Cloning and functional characterization of the Rhizopus oryzae high affinity iron permease (rFTR1) gene. (2004) (49)
- Generation of multi-functional antigen-specific human T-cells by lentiviral TCR gene transfer (2010) (49)
- Expression of vFLIP in a Lentiviral Vaccine Vector Activates NF-κB, Matures Dendritic Cells, and Increases CD8+ T-Cell Responses (2008) (47)
- Retroviral pseudotypes produced by rescue of a Moloney murine leukemia virus vector by C-type, but not D-type, retroviruses. (1992) (46)
- T-cell receptor alpha chain plays a critical role in antigen-specific suppressor cell function. (1991) (46)
- B-cell depletion inhibits arthritis in a collagen-induced arthritis (CIA) model, but does not adversely affect humoral responses in a respiratory syncytial virus (RSV) vaccination model. (2005) (45)
- Human Immunodeficiency Virus Type 1 Vectors with Alphavirus Envelope Glycoproteins Produced from Stable Packaging Cells (2005) (44)
- Conjugation of Lentivirus to Paramagnetic Particles via Nonviral Proteins Allows Efficient Concentration and Infection of Primary Acute Myeloid Leukemia Cells (2005) (44)
- Enhanced GITR/GITRL interactions augment IL‐27 expression and induce IL‐10‐producing Tr‐1 like cells (2012) (43)
- Lentiviral vector expression of tumour antigens in dendritic cells as an immunotherapeutic strategy (2006) (42)
- IL-21 receptor expression determines the temporal phases of experimental autoimmune encephalomyelitis (2008) (42)
- Safer, Silencing-Resistant Lentiviral Vectors: Optimization of the Ubiquitous Chromatin-Opening Element through Elimination of Aberrant Splicing (2012) (41)
- A phagocytic cell line markedly improves survival of infected neutropenic mice (2005) (41)
- Murine Leukemia Virus Particle Assembly Quantitated by Fluorescence Microscopy: Role of Gag-Gag Interactions and Membrane Association (2003) (39)
- Irradiated NC adenocarcinoma cells transduced with both B7.1 and interleukin-2 induce CD4+-mediated rejection of established tumors. (1997) (38)
- Differential Expression of Inducible Costimulator-Ligand Splice Variants: Lymphoid Regulation of Mouse GL50-B and Human GL50 Molecules (2001) (38)
- Cyclosporine Increases Human Immunodeficiency Virus Type 1 Vector Transduction of Primary Mouse Cells (2006) (37)
- Immunotherapeutic potential in murine tumor models of polyinosinic-polycytidylic acid and poly-L-lysine solubilized by carboxymethylcellulose. (1985) (37)
- Lentiviral vectors targeted to MHC II are effective in immunization. (2011) (37)
- vFLIP from KSHV inhibits anoikis of primary endothelial cells (2008) (36)
- Envelope-targeted retrovirus vectors transduce melanoma xenografts but not spleen or liver. (2002) (35)
- Insertional mutagenesis by retroviral vectors: current concepts and methods of analysis. (2013) (35)
- The JNK phosphatase M3/6 is inhibited by protein-damaging stress (2001) (34)
- The combination of chemotherapy and systemic immunotherapy with soluble B7-immunoglobulin G leads to cure of murine leukemia and lymphoma and demonstration of tumor-specific memory responses. (2001) (34)
- Molecular aspects of growth factor action: Receptors and intracellular signals (1983) (34)
- The β-globin locus control region in combination with the EF1α short promoter allows enhanced lentiviral vector-mediated erythroid gene expression with conserved multilineage activity. (2012) (33)
- T cell receptor (TCR) usage determines disease susceptibility in experimental autoimmune encephalomyelitis: studies with TCR V beta 8.2 transgenic mice (1994) (32)
- The pathology and immunology of atopic dermatitis. (2011) (32)
- Therapeutic opportunities in the B7/CD28 family of ligands and receptors. (2005) (32)
- Gene therapy meets vaccine development. (2004) (31)
- Growth factors improve gene expression after lentiviral transduction in human adult and fetal hepatocytes (2007) (31)
- Efficient retroviral vector targeting of carcinoembryonic antigen-positive tumors. (2004) (30)
- Tumor cells secreting IL-13 but not IL-13Ralpha2 fusion protein have reduced tumorigenicity in vivo. (2004) (29)
- A murine cell line producing HTLV-I pseudotype virions carrying a selectable marker gene. (1991) (29)
- Ten years of progress in vaccination against cancer: the need to counteract cancer evasion by dual targeting in future therapies (2011) (28)
- Effect of the Internal Promoter on Insertional Gene Activation by Lentiviral Vectors with an Intact HIV Long Terminal Repeat (2010) (28)
- Comparable in vivo efficacy of CD28/B7, ICOS/GL50, and ICOS/GL50B costimulatory pathways in murine tumor models: IFNgamma-dependent enhancement of CTL priming, effector functions, and tumor specific memory CTL. (2003) (25)
- Immunization of Mice with Lentiviral Vectors Targeted to MHC Class II+ Cells Is Due to Preferential Transduction of Dendritic Cells In Vivo (2014) (25)
- Single-chain antibodies that target lentiviral vectors to MHC class II on antigen-presenting cells. (2009) (23)
- Immunomodulation and antitumor effects of MVE-2 in mice. (1984) (22)
- Harnessing alveolar macrophages for sustained mucosal T-cell recall confers long-term protection to mice against lethal influenza challenge without clinical disease (2013) (19)
- Targeting lentiviral vectors for cancer immunotherapy. (2011) (18)
- TRIL Is Involved in Cytokine Production in the Brain following Escherichia coli Infection (2014) (18)
- Use of Heterologous Vesiculovirus G Proteins Circumvents the Humoral Anti-envelope Immunity in Lentivector-Based In Vivo Gene Delivery (2019) (17)
- Targeted Retroviral Infection of Tumor Cells by Receptor Cooperation (2003) (17)
- Protection From Influenza by Intramuscular Gene Vector Delivery of a Broadly Neutralizing Nanobody Does Not Depend on Antibody Dependent Cellular Cytotoxicity (2020) (17)
- DNA fusion vaccine designs to induce tumor‐lytic CD8+ T‐cell attack via the immunodominant cysteine‐containing epitope of NY‐ESO 1 (2013) (16)
- Kaposi's Sarcoma-Associated Herpesvirus vFLIP and Human T Cell Lymphotropic Virus Type 1 Tax Oncogenic Proteins Activate IκB Kinase Subunit γ by Different Mechanisms Independent of the Physiological Cytokine-Induced Pathways (2011) (16)
- Expression of functional alpha beta T cell receptor gene rearrangements in suppressor T cell hybridomas correlates with antigen binding, but not with suppressor cell function. (1990) (15)
- Characterization of Antibody Interactions with the G Protein of Vesicular Stomatitis Virus Indiana Strain and Other Vesiculovirus G Proteins (2018) (13)
- Cell-surface and cytokine biomarkers in autoimmune and inflammatory diseases. (2006) (13)
- Cytosolic Phospholipase A2α Blockade Abrogates Disease during the Tissue-Damage Effector Phase of Experimental Autoimmune Encephalomyelitis by Its Action on APCs (2011) (13)
- Lentivector targeting to dendritic cells. (2008) (12)
- Optimization of a myeloid cell transfusion strategy for infected neutropenic hosts. (2007) (12)
- Vulvar Application of Lidocaine for Pain Relief in Spontaneous Vaginal Delivery (1994) (12)
- Unexpected Targets and Triggers of Autoimmunity (2014) (11)
- Gene transfer to repopulating human CD34+cells using amphotropic, GALV or RD114 pseudotyped HIV-1 based vectors from stable producer cells. (2004) (11)
- A lentiviral vector pseudotype suitable for vaccine development (2011) (11)
- T cell receptor alpha-chain defines the antigen specificity of antigen-specific suppressor factor but does not impart genetic restriction. (1995) (11)
- A FLIPR-based assay to assess potency and selectivity of inhibitors of the TEC family kinases Btk and Itk. (2007) (10)
- Tumor models to investigate the therapeutic efficiency of immunomodulators. (1984) (10)
- Lentivector Producer Cell Lines with Stably Expressed Vesiculovirus Envelopes (2018) (10)
- Characterization of a B cell helper factor(s) derived from CD5+ B cell hybridomas. (1990) (9)
- Distinct in vitro binding properties of the anti-CD20 small modular immunopharmaceutical 2LM20-4 result in profound and sustained in vivo potency in cynomolgus monkeys (2011) (9)
- Transfection of TCR alpha-chains into suppressor and T helper cell hybridomas. Production of suppressor factors with predicted antigen specificity. (1995) (9)
- Effect of the Internal Promoter on Insertional Gene Activation by Lentiviral Vectors with an Intact HIV Long Terminal Repeat (2010) (9)
- Spontaneous Heteromerization of Gammaretrovirus Envelope Proteins: a Possible Novel Mechanism of Retrovirus Restriction (2008) (8)
- In Vivo Gene Delivery to Lymph Node Stromal Cells Leads to Transgene-specific CD8+ T Cell Anergy in Mice. (2016) (8)
- Antigen Specific Suppressor Cells, Receptors, and Factors (1989) (8)
- Using a prime and pull approach, lentivector vaccines expressing Ag85A induce immunogenicity but fail to induce protection against Mycobacterium bovis bacillus Calmette–Guérin challenge in mice (2015) (8)
- Mass spectrometry analysis reveals differences in the host cell protein species found in pseudotyped lentiviral vectors (2018) (8)
- 4-1BB Ligand Activates Bystander Dendritic Cells To Enhance Immunization in Trans (2014) (8)
- Bone Formation, Growth, and Repair (2016) (7)
- Effect of treatments environment (temperature, pH, water activity (aw) on the heat resistance of yeasts (1992) (7)
- Physical attraction of Th9 cells is skin deep. (2015) (6)
- Comparison of antibody isotypes in sera and circulating immune complexes during tumor growth and metastasis of three tumor models in mice. (1984) (6)
- Lentiviral vector followed by protein immunisation breaks tolerance against the self‐antigen Her1 and results in lung cancer immunotherapy (2012) (5)
- The DTH effector response and IL-2 are unaffected by cyclosporine A in autoimmune B6D2F1 mice. (2010) (5)
- Optimization of a myeloid cell transfusion strategy for infected neutropenic hosts (2007) (5)
- Hamster cDNA homologs to the mouse immunoglobulin kappa constant and Igk-V 45.1 genes (2004) (5)
- Encephalomyelitis Experimental Autoimmune Clone DownRegulate Adoptive Transfer of Altered Peptide Ligand-Specific Th 2 Cell from an β IL-4 , IL-10 , IL-13 , and TGF-and Mary Collins (2000) (4)
- Enhancing the purification of Lentiviral vectors for clinical applications (2021) (4)
- Hamster cDNA homologs to the mouse immunoglobulin IgG2 constant and Igh-Vh10 genes (2004) (4)
- IL-22, A Th17 Cytokine, induces a systemic acute phase response (2009) (4)
- Regulating with Reg proteins: a new role in Th17 cell-mediated skin inflammation. (2012) (4)
- Escape from R-peptide deletion in a γ-retrovirus. (2011) (3)
- 53 IL-22, a TH17 and TH1 Cytokine, Regulates Local Tissue Inflammation in the Context of Autoimmune Disease (2007) (3)
- Lentiviral expression of GAD67 and CCK promoter‐driven opsins to target interneurons in vitro and in vivo (2016) (2)
- Inhibitors of Poly(ADP-Ribose) Polymerase Block the Infection of Mammalian Cells by Retroviral Vectors (1992) (2)
- Retroviral vectors for cancer gene therapy. (2000) (2)
- Sustained antigen presentation after lentiviral immunization (2008) (2)
- Tubulovesicular structures within VSV-G pseudotyped lentiviral vector preparations carry DNA and stimulate anti-viral responses via toll-like receptor 9 (2007) (2)
- Tipping the balance in autoimmune disease (2007) (2)
- A clinical-grade constitutive packaging cell line for the production of self-inactivating lentiviral vectors (2013) (2)
- Effect of heat treatment on aerobically and anaerobically grown or starved yeast cell in different pH menstrua (1992) (1)
- The role of the T cell receptor alpha chain in antigen-specific immune suppression. (1993) (1)
- CTLA4IG FAILS TO PREVENT INTESTINAL ALLOGRAFT REJECTION DUE TO AN INABILITY TO INHIBIT CD8 T CELL RESPONSES (1999) (1)
- Airway Neutrophil Recruitment Produced by Mouse Th 17 Cells and Induces An IL-17 F / A Heterodimer Protein Is Wright and (2007) (1)
- IL-21 modulates cytokine levels in murine collagen-induced arthritis and contributes to disease pathology (2007) (1)
- Complex responses to a diverse environment (2008) (1)
- Non-integrating lentiviral vectors for immunization (2007) (1)
- Suppression by CD 4 T Cells by its Ligand Mediates Resistance to TNFR Family-Related Receptor on Effector Engagement of Glucocorticoid-Induced (2004) (1)
- Airway Neutrophil Recruitment Produced by Mouse Th17 Cells and Induces An IL-17F/A Heterodimer Protein Is (2007) (1)
- Book reviewDeath defyingApoptosis and the Immune Response edited by Christopher D. Gregory, Wiley-Liss, 1995. £69.00 (416 pages) ISBN 0 477 01257 3 (1996) (1)
- F.18. Itk-deficient Mice are Resistant to Experimental Autoimmune Encephalomyelitis (EAE) (2008) (1)
- Fibrous Dysplasia: A Model Disease for the Study of cAMP in Bone (2012) (1)
- 223 IL-22R, IL-10R2 and IL-22BP binding sites are topologically juxtaposed on adjacent and overlapping surfaces of IL-22 (2008) (1)
- Therapeutic application of selective ERK activation for the treatment of inflammatory arthritis (2010) (1)
- Sa.19. Autoreactive T-Cells Mediate NK Cell Degeneration in Autoimmune Disease (2006) (1)
- Increased expression of the chemokines CXCL10 and CXCL11 are associated with the development of graft-versus-host disease (2011) (1)
- IL-22 is Required for Th17 Cell Mediated Skin Inflammation in Murine Model of Psoriasis (2008) (1)
- IL-21 Receptor Is Critical for the Heath (2010) (0)
- Role of IL‐21R in the pathogenesis of murine models of SLE (2008) (0)
- Title: CD8+CD62LhiCD25- cells induce skin inflammation in a psoriasis-like disease model and exhibit a Th1 phenotype (137.19) (2009) (0)
- Retroviral vectors are produced by resistant to lysis by human serum production cell (1995) (0)
- Comparative analysis of cellular proteins in stably and transiently produced lentiviral vectors (2013) (0)
- The novel and selective JAK3 inhibitor WYE-152038 is highly efficacious in a mouse model of rheumatoid arthritis (2009) (0)
- Activated Primary B Cells IL-21 Induces the Apoptosis of Resting and (2003) (0)
- MMP9 Plays an Essential Role in the Development of Experimental Colitis in Mice (2010) (0)
- TRIL is a novel modulator of TLR4 with enriched expression in the brain (2009) (0)
- A biomarker panel associated with acute and chronic graft-versus-host disease (2010) (0)
- DIFFERENT EFFECTS OF VARIOUS STRATEGIES FOR BLOCKING CD28/B7 INTERACTIONS ON INTESTINAL ALLOGRAFT REJECTION.: Abstract# 1165 (2000) (0)
- The role of in vivo PD-1/PD-L1 interactions in syngeneic and allogeneic antitumor responses in murine tumor models (2001) (0)
- Book Review:Biochemistry of Cellular Regulation. Volume 3: Development and Differentiation. Michael J. Clemens (1983) (0)
- Long-term expression from non-integrating lentiviral vectors in muscle (2007) (0)
- Inhibition of local and disseminated tumor growth by IL-2 (1991) (0)
- Development of a gene expression system for enhanced erythroid expression (2011) (0)
- The functional activity of human IL-17A, IL-17F and IL-17A/IL-17F cytokines is dependent on the receptors IL-17R and IL-17RC (94.31) (2007) (0)
- Sa.50. IL-21 Has a Pathogenic Role in Disease Progression in Lupus-Prone Mice (2006) (0)
- CTL Response Encoding NY-ESO-1 Induces an Effective Intravenous Injection of a Lentiviral Vector (2004) (0)
- Immunization with a Lentivector That Targets Tumor Antigen Expression to Dendritic Cells Induces Potent CD8 (cid:1) and CD4 (cid:1) T-Cell Responses (cid:1) (2007) (0)
- Methods and compositions for modulating the activity of interleukin-21 (2002) (0)
- Improved safety of Lentiviral vectors containing silencing resistant A2UCOE regulatory elements (2012) (0)
- Organisation and Expression of Human T Cell Receptor Genes (1986) (0)
- An experimental model set-up to study MHC class II targeted gene transfer in antigen-presenting-cells (2011) (0)
- IL-21R is critical for the development of memory responses (150.9) (2011) (0)
- Molecular Studies of the Human T-Cell Antigen Receptor (1985) (0)
- Unexpected Targets and Triggers of Autoimmunity (2014) (0)
- S.101. TNFa Blockade Exacerbates Disease in a Psoriasis-like Skin Inflammation Model Through Enhancing Th17 Cell Function while Suppressing CD4+Foxp3+T Cell Expansion (2009) (0)
- Methods for the treatment and prevention of fibrosis (2006) (0)
- A FLIPR-based Assay to Assess Potency of Inhibitors of the TEC Family Kinases Itk and Btk (2007) (0)
- Engineering retroviruses for gene delivery (2003) (0)
- 110 Role of IL21R in the pathogenesis of murine models of SLE (2008) (0)
- The Role of the T Cell Receptor α Chain in Antigen‐Specific Immune Suppression (1993) (0)
- P76 Lentiviral vectors co-expressing hepatitis B core and vFLIP induce potent CD8 T-cell and antibody responses in HLA-A2 transgenic mice (2010) (0)
- Glucocorticoid induced TNF Receptor Ligand (GITRL) transgenic mice develop T and B lymphocyte hyperplasia and expansion of CD4+ FOXP3+ cells (2008) (0)
- Meeting Report (1991) (0)
- Beneficial Effect of IgG Glycan Hydrolysis by EndoS in Central Nervous System Autoimmunity (P07.084) (2012) (0)
- Role of Th1, Th2 and Th17 cytokines on the expression of various inflammatory cytokines, defensive proteins and chemokines by primary human epithelial keratinocytes (148.10) (2011) (0)
- Gene transfer to repopulating human CD34+cells using amphotropic or RD114 pseudotyped HIV-1 based vectors from permanent producer cell lines (STAR) (2003) (0)
- Encephalomyelitis by Its Action on APCs Effector Phase of Experimental Autoimmune Abrogates Disease during the Tissue-Damage Blockade a 2 Cytosolic Phospholipase A (2011) (0)
- Lentiviral TCR gene transfer for adoptive immunotherapy of cancer (2008) (0)
- Sa.34. Interleukin-21 Receptor-deficient MRL-Faslpr Lupus Prone Mice Have Significantly Reduced B Cell-mediated Pathogenesis and Delayed Disease Progression (2008) (0)
- Short title: Effect of B cell depletion in CIA and RSV models (2005) (0)
- Efficient immunization by a novel lentivector re-targeted to MHC II (2009) (0)
- Lentiviral Vectors Encoding Influenza A Nucleprotein and vFLIP Induce Potent CD8 T-Cell Responses and Confer Protection Against Lethal Flu Challenge (2010) (0)
- Pro-inflammatory Th17 cytokines stimulate the expression of novel IL-1 cytokines in vitro and in vivo: Implications in psoriasis pathogenesis (2009) (0)
- Abstracts ‐ Tuesday 24th July 2001 (2001) (0)
- Modulation of the immune response by lentivector targeting of intracellular pathways (2007) (0)
- Antibodies directed against the receptor il-21 human and use thereof. (2004) (0)
- Her1 vaccine for epithelial tumors therapy: primeboosting strategy based on lentiviral-protein vaccination to potentiate the vaccine effect (2012) (0)
- Sa.140. Neutralization of Interleukin 21 Results in Suppression of Colitis in Mice Adoptively Transplanted with CD45RBHi CD4+ T-Cells (2006) (0)
- Degeneration in Autoimmune Disease Autoreactive T Cells Mediate NK Cell (2006) (0)
- Lentiviral Vectors for TCR Gene Transfer: Improved Function of TCR-Transduced T Cells After Non-Activating Cytokine-Mediated Transduction (2010) (0)
- The Interleukin 21 Pathway is Involved in the Development of Experimental Colitis in Mice (2010) (0)
- ATTENUATION OF rmlL‐12 TOXICITY AND IFN‐y PRODUCTION BY PRETREATMENT WITH RMIL‐12: 332 (1997) (0)
- Role of Th2 cytokines in adoptive transfer of EAE (1998) (0)
- IL-21R is required for the systemic accumulation of activated B and T lymphocytes in MRLlpr mice (117.9) (2011) (0)
- Non-Integrating Lentiviral Vectors for Vaccination (2009) (0)
- IL-21 Receptor Modulates Autoimmune Responses and Expression of Experimental Autoimmune Encephalomyelitis (2007) (0)
- HIV-1 vectors with alphavirus envelope glycoproteins produced from stable packaging cells (2005) (0)
- Sensitivity of Lentiviral Vectors Pseudotyped with Vesiculovirus G Proteins to Inactivation by Human Serum Complement (2017) (0)
- with IL-21R.Fc Reduces Disease Progression Lupus-Prone Mouse Model and Its Blockade IL-21 Has a Pathogenic Role in a (2017) (0)
- PS1-06 TNFα blockade exacerbates murine psoriasis-like skin inflammation by enhancing Th17 function and preventing expansion of regulatory T cells (2010) (0)
- IL-17 RA / IL-17 RC Receptor Complex Cytokine Signals through the The Human IL-17 F / IL-17 A Heterodimeric and (2008) (0)
- In vivo immunization against male antigens and GFP, with lentiviruses targeted to MHC class II positive cells (2011) (0)
- Development of safety improved lentiviral vectors containing ubiquitous chromatin opening elements (2009) (0)
- Human GL 50 Molecules Lymphoid Regulation of Mouse GL 50B and Costimulator-Ligand Splice Variants : Differential Expression of Inducible Marusic (2001) (0)
- IL‐22 directly induces keratinocyte hyperplasia, up‐regulates anti‐microbial peptide and pro‐inflammatory cytokine gene expression in mouse skin (2008) (0)
- Enhanced GITR/GITRL Interactions Augment IL-27 Production and Induce IL-10-producing Tr-1 Cells (2010) (0)
- T.124. Mutation P331S in the Fc Domain of an Anti-CD20 SMIP™ Protein Confers Impaired in vivo B Cell Depletion Activity in Lymphoid Tissues of Cynomolgus Monkeys (2009) (0)
- New Therapies in Metabolic Bone Disease: Denusomab (2014) (0)
- Retrospective: Drug Design amongst the Vines 2006 (2007) (0)
- Beneficial effects of HDAC6 inhibition on airway epithelial barrier function (2019) (0)
- Hyaluronic acid-targeted metabolism in Acute Respiratory Distress Syndrome (2022) (0)
- Regulating dendritic cell signalling to improve vaccination (2012) (0)
- Modifying antigen presenting cells (2001) (0)
- Potential sources of anti-adhesive oligosaccharides against canine gastrointestinal pathogens. (2005) (0)
- Retrospective: Connect 2005 - Part I (2005) (0)
- Lentiviral Vectors as Vaccines (2009) (0)
- Cocal Virus Envelope Protein G for Generating Stable Lentiviral Vector Packaging Cell Line (2017) (0)
- Tuesday Poster Sessions (2009) (0)
- 458. Development of Non-Integrating and Site- Specifically Integrating Lentiviral Vectors (2006) (0)
- Insertional Mutagenesis by Lentiviral Vectors (2010) (0)
- SEC purification of lentiviral vectors: comparison of RD114 pseudotypes produced by stable packaging cells and transiently produced VSV-G pseudotypes (2011) (0)
- Peptide regulatory factors: edited by T. Green et al., Edward Arnold, 1989. £9.95 (xii + 164 pages) ISBN 0 340 52452 9 (1990) (0)
- Pd-1 antibodies and their uses. (2003) (0)
- Development of non-integrating lentiviral vectors (2006) (0)
- Optimization of clarification process for viral vectors (2020) (0)
- Insertional mutagenesis by retroviral and lentiviral vectors (2008) (0)
- ICOS Receptor B 7-Like Protein That Functionally Binds to Cutting Edge : Identification of GL 50 , a Novel Miyashiro (2000) (0)
- In vitro and in vivo expression regulation of PD-1 and PD-L1 in murine tumor models (2001) (0)
- CTLA-4 (CD152) Surface-Linked Single-Chain Antibody to Blockade of T Cell Activation Using a (2000) (0)
- Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity (114.16) (2011) (0)
- Immunisation with a lentivector that targets tumour antigen expression to dendritic cells induces potent CD 8 + and CD 4 + T cell responses (2007) (0)
- Treatment of fibrosis meidante antagonism of IL-3 and receptor chains yl-3. (2000) (0)
- /J Mice lpr/lpr Lymphocytes in MRL/MpJ-Fas Accumulation of Activated B and T IL-21 Receptor Is Required for the Systemic (2012) (0)
- Targeted Activation of ERK Pathway with Lentiviral Vectors to Induce Antigen-Specific Peripheral Tolerance (2010) (0)
- Murine IL-13 Receptor Cloning , Characterization , and Comparison 2 : Molecular α The Murine IL-13 Receptor (1998) (0)
- IL-21 , But Not CD 28 , IL-7 , and IL-15 andProliferation : Attenuation of ICOS , IL-4 , Costimulation and Cytokine-Driven Activation Has Distinct Effects on Program Death-1 Engagement Upon TCR (2002) (0)
- Antibodies against IL21-receptor and their use (2004) (0)
- Inhibition of polymerase to treat viral infection (1991) (0)
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