Mary E. Klotman | Academic Influence

Mary E. Klotman's AcademicInfluence.com Rankings

Mary E. Klotman

Philosophy

#11430

World Rank

#15737

Historical Rank

#2181

USA Rank

Logic

#8251

World Rank

#10299

Historical Rank

#1341

USA Rank

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Philosophy

Mary E. Klotman's Degrees

Bachelors Biology Duke University

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Why Is Mary E. Klotman Influential?

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According to Wikipedia, Mary Frances Earley Klotman is an American physician-scientist and academic administrator. She was elected as a member of the National Academy of Medicine in 2014 and became the editor of the Annual Review of Medicine in 2020. She has been the dean of the Duke University School of Medicine since 2017.

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Mary E. Klotman's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Mutations in the chemokine receptor gene CXCR4 are associated with WHIM syndrome, a combined immunodeficiency disease (2003) (649)
Defensins in innate antiviral immunity (2006) (459)
Nephropathy and establishment of a renal reservoir of HIV type 1 during primary infection. (2001) (322)
Renal epithelium is a previously unrecognized site of HIV-1 infection. (2000) (308)
Replication and compartmentalization of HIV-1 in kidney epithelium of patients with HIV-associated nephropathy (2002) (299)
Progressive glomerulosclerosis and enhanced renal accumulation of basement membrane components in mice transgenic for human immunodeficiency virus type 1 genes. (1992) (290)
Kinetics of expression of multiply spliced RNA in early human immunodeficiency virus type 1 infection of lymphocytes and monocytes. (1991) (211)
Highly active antiretroviral therapy and the epidemic of HIV+ end-stage renal disease. (2005) (201)
Human immunodeficiency virus (HIV)‐1 infects human hepatic stellate cells and promotes collagen I and monocyte chemoattractant protein‐1 expression: Implications for the pathogenesis of HIV/hepatitis C virus–induced liver fibrosis (2010) (200)
Protein isoforms encoded by the pX region of human T-cell leukemia/lymphotropic virus type I. (1992) (199)
Acute renal failure in hospitalized patients with HIV: risk factors and impact on in-hospital mortality (2006) (190)
Dual role of a-defensin-1 in antiHIV-1 innate immunity (2005) (189)
HIV-associated nephropathy is a late, not early, manifestation of HIV-1 infection. (1999) (183)
Chronic kidney disease in HIV infection: an urban epidemic (2007) (177)
Prophylactic intravenous amphotericin B in neutropenic autologous bone marrow transplant recipients. (1992) (174)
Nef stimulates proliferation of glomerular podocytes through activation of Src-dependent Stat3 and MAPK1,2 pathways. (2004) (167)
Single-dose safety, pharmacology, and antiviral activity of the human immunodeficiency virus (HIV) type 1 entry inhibitor PRO 542 in HIV-infected adults. (2000) (156)
Expression of alternatively spliced human T-lymphotropic virus type I pX mRNA in infected cell lines and in primary uncultured cells from patients with adult T-cell leukemia/lymphoma and healthy carriers. (1992) (149)
p53 functional impairment and high p21waf1/cip1 expression in human T-cell lymphotropic/leukemia virus type I-transformed T cells. (1996) (144)
HIV-1 Nef induces proliferation and anchorage-independent growth in podocytes. (2002) (142)
alpha-Defensin inhibits influenza virus replication by cell-mediated mechanism(s). (2007) (141)
The spectrum of kidney disease in patients with AIDS in the era of antiretroviral therapy. (2009) (125)
Phosphatidylinositol 3-Kinase Regulates Human Immunodeficiency Virus Type 1 Replication following Viral Entry in Primary CD4+ T Lymphocytes and Macrophages (2003) (120)
Candidate Sulfonated and Sulfated Topical Microbicides: Comparison of Anti-Human Immunodeficiency Virus Activities and Mechanisms of Action (2005) (119)
Dual role of alpha-defensin-1 in anti-HIV-1 innate immunity. (2005) (119)
APOL1 variants increase risk for FSGS and HIVAN but not IgA nephropathy. (2011) (118)
CAF-Mediated Human Immunodeficiency Virus (HIV) Type 1 Transcriptional Inhibition Is Distinct from α-Defensin-1 HIV Inhibition (2003) (108)
Specific inhibition of human immunodeficiency virus type 1 replication by antisense oligonucleotides: an in vitro model for treatment. (1992) (105)
Candidate Topical Microbicides Bind Herpes Simplex Virus Glycoprotein B and Prevent Viral Entry and Cell-to-Cell Spread (2004) (100)
Human immunodeficiency virus (HIV) infects human arterial smooth muscle cells in vivo and in vitro: implications for the pathogenesis of HIV-mediated vascular disease. (2008) (100)
PRO 2000 gel inhibits HIV and herpes simplex virus infection following vaginal application: a double-blind placebo-controlled trial. (2006) (95)
Successful immunization with a single injection of non-integrating lentiviral vector. (2007) (92)
HIV envelope gp120 activates human arterial smooth muscle cells (2001) (92)
HIV-1 Nef induces dedifferentiation of podocytes in vivo: a characteristic feature of HIVAN (2005) (88)
Role of ubiquitin-like protein FAT10 in epithelial apoptosis in renal disease. (2006) (88)
Cervicovaginal secretions contribute to innate resistance to herpes simplex virus infection. (2005) (87)
Neisseria gonorrhoeae-Induced Human Defensins 5 and 6 Increase HIV Infectivity: Role in Enhanced Transmission1 (2008) (85)
HIV-1 Infection Initiates an Inflammatory Cascade in Human Renal Tubular Epithelial Cells (2006) (84)
Virological synapses allow HIV-1 uptake and gene expression in renal tubular epithelial cells. (2011) (80)
Prothymosin-α inhibits HIV-1 via Toll-like receptor 4-mediated type I interferon induction (2010) (79)
Polymerase chain reaction amplification and in situ hybridization for the detection of human B-lymphotropic virus. (1988) (76)
HIV-1 extrachromosomal 2-LTR circular DNA is long-lived in human macrophages. (2005) (72)
Defensins: natural anti-HIV peptides. (2004) (70)
Pseudomonas putrefaciens bacteremia. (1989) (68)
Mandelic Acid Condensation Polymer: Novel Candidate Microbicide for Prevention of Human Immunodeficiency Virus and Herpes Simplex Virus Entry (2002) (67)
Reduction of Stat3 activity attenuates HIV-induced kidney injury. (2009) (66)
Identification of a novel cell attachment domain in the HIV-1 Tat protein and its 90-kDa cell surface binding protein. (1993) (64)
Podocan, a Novel Small Leucine-rich Repeat Protein Expressed in the Sclerotic Glomerular Lesion of Experimental HIV-associated Nephropathy* (2003) (61)
A Soluble Factor(s) Secreted from CD8+ T Lymphocytes Inhibits Human Immunodeficiency Virus Type 1 Replication through STAT1 Activation (2002) (59)
Neisseria gonorrhoeae Enhances HIV-1 Infection of Primary Resting CD4+ T Cells through TLR2 Activation (2010) (59)
Lentiviral gene transduction of kidney. (2002) (56)
HIV-1 viral protein r induces ERK and caspase-8-dependent apoptosis in renal tubular epithelial cells (2010) (55)
Detection of mouse cytomegalovirus nucleic acid in latently infected mice by in vitro enzymatic amplification. (1990) (54)
Trans-activating rev protein of the human immunodeficiency virus 1 interacts directly and specifically with its target RNA. (1990) (53)
ACIDFORM inactivates herpes simplex virus and prevents genital herpes in a mouse model: optimal candidate for microbicide combinations. (2006) (52)
Amplification of HIV-1 provirus from cerebrospinal fluid and its correlation with neurologic disease. (1990) (47)
Novel Function of Prothymosin Alpha as a Potent Inhibitor of Human Immunodeficiency Virus Type 1 Gene Expression in Primary Macrophages (2006) (46)
FAT10: a Novel Mediator of Vpr-Induced Apoptosis in Human Immunodeficiency Virus-Associated Nephropathy (2009) (45)
Development and use of SIV-based Integrase defective lentiviral vector for immunization. (2009) (45)
Growth failure and AIDS-like cachexia syndrome in HIV-1 transgenic mice. (1994) (43)
HIV-1 Vpr inhibits cytokinesis in human proximal tubule cells. (2008) (42)
Inhibition of Rev activity and human immunodeficiency virus type 1 replication by antisense oligodeoxynucleotide phosphorothioate analogs directed against the Rev-responsive element (1993) (40)
Retroviral E‐DNA: persistence and gene expression in nondividing immune cells (2006) (37)
Nef expressed from human immunodeficiency virus type 1 extrachromosomal DNA downregulates CD4 on primary CD4+ T lymphocytes: implications for integrase inhibitors. (2005) (35)
Patterns of HIV-1 mRNA expression in transgenic mice are tissue-dependent. (1994) (34)
HIV-1 infection stimulates T cell invasiveness and synthesis of the 92-kDa type IV collagenase. (1993) (34)
Increased Expression of α4β1 and α5β1 Integrins on HTLV-I-Infected Lymphocytes (1993) (34)
Superfibronectin, a Multimeric Form of Fibronectin, Increases HIV Infection of Primary CD4+ T Lymphocytes1 (2000) (33)
Gonococcal lipooligosaccharide suppresses HIV infection in human primary macrophages through induction of innate immunity. (2006) (33)
Immunization with an SIV-based IDLV Expressing HIV-1 Env 1086 Clade C Elicits Durable Humoral and Cellular Responses in Rhesus Macaques (2016) (33)
Epstein-Barr virus and the elderly host. (1989) (32)
The homophilic adhesion molecule sidekick‐1 contributes to augmented podocyte aggregation in HIV‐associated nephropathy (2007) (31)
Transduction of human antigen-presenting cells with integrase-defective lentiviral vector enables functional expansion of primed antigen-specific CD8(+) T cells. (2010) (31)
Erratum: Kinetics of expression of multiply spliced RNA in early human immunodeficiency virus type 1 infection of lymphocytes and monocytes (Proc. Natl. Acad. Sci. USA (June 1991) 88 (5011-5015)) (1992) (30)
Renal epithelial cells produce and spread HIV-1 via T-cell contact (2014) (29)
HIV-1 infection of human T lymphocytes results in enhanced alpha 5 beta 1 integrin expression (1991) (29)
Postintegration HIV-1 infection of cervical epithelial cells mediates contact-dependent productive infection of T cells. (2013) (28)
SAMMA, a mandelic acid condensation polymer, inhibits dendritic cell‐mediated HIV transmission (2007) (28)
Molecular therapy for renal diseases. (1996) (27)
CD8+ cell lines isolated from HIV-1-infected children have potent soluble HIV-1 inhibitory activity that differs from beta-chemokines. (2000) (26)
Simian immunodeficiency virus-Vpx for improving integrase defective lentiviral vector-based vaccines (2012) (25)
IDLV-HIV-1 Env vaccination in non-human primates induces affinity maturation of antigen-specific memory B cells (2018) (24)
The source of murine cytomegalovirus in mice receiving kidney allografts. (1985) (23)
Nonintegrating Lentiviral Vector-Based Vaccine Efficiently Induces Functional and Persistent CD8+ T Cell Responses in Mice (2010) (23)
The HIV-positive traveler. (2007) (23)
Rigorous pre-clinical evaluation of topical microbicides to prevent transmission of human immunodeficiency virus. (2003) (22)
In vivo gene transfer to kidney by lentiviral vector. (2002) (22)
Persulfated molecular umbrellas as anti-HIV and anti-HSV agents. (2004) (22)
HIV-1 Vpr activates the DNA damage response in renal tubule epithelial cells (2009) (22)
Novel Small Leucine-Rich Repeat Protein Podocan Is a Negative Regulator of Migration and Proliferation of Smooth Muscle Cells, Modulates Neointima Formation, and Is Expressed in Human Atheroma (2013) (22)
Career Outcomes of the Graduates of the American Board of Internal Medicine Research Pathway, 1995–2007 (2013) (21)
Identification of HIV-1 genitourinary tract compartmentalization by analyzing the env gene sequences in urine (2015) (20)
Mucosal Human Defensins 5 and 6 Antagonize the Anti-HIV Activity of Candidate Polyanion Microbicides (2010) (20)
Influence of Prothymosin‐α on HIV‐1 Target Cells (2007) (19)
A fine line between molecular umbrella transport and ionophoric activity. (2009) (18)
Dual tropism of HIV-1 envelopes derived from renal tubular epithelial cells of patients with HIV-associated nephropathy (2006) (17)
Inhibitory Effect of PRO 2000, a Candidate Microbicide, on Dendritic Cell-Mediated Human Immunodeficiency Virus Transfer (2008) (17)
Skeletal Muscle Is an Antigen Reservoir in Integrase-Defective Lentiviral Vector-Induced Long-Term Immunity (2020) (16)
Influence of prothymosin-alpha on HIV-1 target cells. (2007) (16)
Detection of Donor's HIV Strain in HIV-Positive Kidney-Transplant Recipient. (2020) (16)
High-dose combination cyclophosphamide, cisplatin, and melphalan with autologous bone marrow support (1989) (14)
Development of Topical Microbicides for Prevention of Human Immunodeficiency Virus and Herpes Simplex Virus (2003) (13)
Optimization of Mucosal Responses after Intramuscular Immunization with Integrase Defective Lentiviral Vector (2014) (11)
cDNA sequencing confirms HTLV-I expression in adult T-cell leukemia/lymphoma and different sequence variations in vivo and in vitro. (1992) (11)
Therapeutic vaccination with IDLV-SIV-Gag results in durable viremia control in chronically SHIV-infected macaques (2020) (11)
Adeno-Associated Virus Gene Transfer into Renal Cells: Potential for in vivo Gene Delivery (1998) (11)
Increased expression of alpha 4 beta 1 and alpha 5 beta 1 integrins on HTLV-I-infected lymphocytes. (1993) (11)
Polyploidy and Mitotic Cell Death Are Two Distinct HIV-1 Vpr-Driven Outcomes in Renal Tubule Epithelial Cells (2017) (11)
Proliferation of HIV-infected renal epithelial cells following virus acquisition from infected macrophages (2020) (10)
3 – Human Immunodeficiency Virus (HIV) Gene Structure and Genetic Diversity (1991) (7)
Kidney and central nervous system as reservoirs of HIV infection (2006) (7)
Prevalence and predictors of proteinuria in HIV-infected and uninfected pregnant women in Cameroon. (2011) (7)
The Differential Binding and Activity of PRO 2000 Against Diverse HIV-1 Envelopes (2009) (7)
HIV infection-induced transcriptional program in renal tubular epithelial cells activates a CXCR2-driven CD4+ T-cell chemotactic response (2016) (7)
Proliferation of HIV-infected renal epithelial cells following virus acquisition from infected macrophages. (2020) (6)
Topical microbicides: the time has come. (2006) (5)
Immunogenicity, safety, and efficacy of sequential immunizations with an SIV-based IDLV expressing CH505 Envs (2020) (5)
The imperative to invest in science has never been greater. (2014) (4)
HIV-1 diversity and compartmentalization in urine, semen, and blood (2020) (4)
HIV-1 dynamics in haemodialysis patients. (2002) (4)
Unsung Hero Robert C. Gallo (2009) (4)
Editorial comment: renal insufficiency in HIV-infected patients may not always be HIVAN. (2002) (4)
Immunogenicity, safety, and efficacy of sequential immunizations with an SIV-based IDLV expressing CH505 Envs (2020) (3)
Safety and efficiency modifications of SIV-based integrase-defective lentiviral vectors for immunization (2021) (3)
DETERMINANTS OF THE SOURCE OF CYTOMEGALOVIRUS IN MURINE RENAL ALLOGRAFT RECIPIENTS (1987) (3)
HIV-1 infection of the kidney: mechanisms and implications. (2020) (3)
Soluble Factors Mediating Innate Immune Responses to HIV Infection (2018) (3)
HIV and the Kidney: From HIV-Associated Nephropathy to Reservoir. (2019) (3)
Polarity of alpha-galactosidase A uptake by renal tubule cells. (2002) (3)
Potential role for G-protein coupled receptors in HIV-associated nephropathy. (1998) (3)
Polarity of α-galactosidase A uptake by renal tubule cells (2002) (3)
Polystyrene Sulfonate Is a Safe and Effective Candidate Topical Antimicrobial for the Prevention of Sexually Transmitted Diseases (1999) (3)
Functional Impairment and High p 21 waf 1 ' cip 1 Expression in Human T-cell LymphotropidLeukemia Virus Type I-Transformed T Cells (2002) (2)
Establishment, Persistence, and Reactivation of Latent HIV-1 Infection in Renal Epithelial Cells (2022) (2)
Kinetics of expression of multiply spliced RNA in early human immunodeficiency virus type 1 infection of lymphocytes and monocytes. (1992) (2)
Tubular-specific expression of HIV protein Vpr leads to severe tubulointerstitial damage accompanied by progressive fibrosis and cystic development. (2022) (1)
Cytomegalovirus pneumonia. (1987) (1)
AIDS and the kidney. Introduction. (1998) (1)
Persistent immunogenicity of integrase defective lentiviral vectors delivering membrane-tethered native-like HIV-1 envelope trimers (2021) (1)
Therapeutic vaccination with IDLV-SIV-Gag results in durable viremia control in chronically SHIV-infected macaques (2020) (1)
Simian immunodeficiency virus-Vpx for improving integrase defective lentiviral vector-based vaccines (2012) (1)
Murine granulocyte-macrophage colony-stimulating factor expressed from a bicistronic simian immunodeficiency virus-based integrase-defective lentiviral vector does not enhance T-cell responses in mice. (2014) (1)
IDLV-HIV-1 Env vaccination in non-human primates induces affinity maturation of antigen-specific memory B cells (2018) (0)
H-101 Potential of integrase-defective lentiviral vectors for HIV vaccine delivery (2018) (0)
CAF-Mediated Human Immunodeﬁciency Virus (HIV) Type 1 Transcriptional Inhibition Is Distinct from (cid:2) -Defensin-1 HIV Inhibition (2003) (0)
HIV-1 infection of renal epithelial cells: 30 years of evidence from transgenic animal models, human studies and in vitro experiments (2023) (0)
Viral Respiratory Tract Infections in Older Adults (2007) (0)
Respiratory Viruses and Hepatitis (2008) (0)
CORRELATION OF IMMUNE RESPONSES WITH HIV PLASMA VIREMIA. † 1074 (1996) (0)
Strong HIV-1 inhibitory activity by antisense phosphorothioate oligonucleotides targeted to HIV-1 untranslated leader sequences (1995) (0)
Primary CD4+ T Lymphocytes Fibronectin, Increases HIV Infection of Superfibronectin, a Multimeric Form of (2013) (0)
HIV-1 Infection of Human T Lymphocytes Results in Enhanced a s 01 Integrin Expression (2002) (0)
Call to arms during disruption. (2020) (0)
Chapter 24 – Renal Manifestations of HIV Infection (2003) (0)
Phenotypic Characterization of Human Immunodeficiency Virus Type I (HIV-1) Envelopes Derived from Kidney and Blood of Patients with HIVAN (2004) (0)
through TLR2 Activation T Cells + Infection of Primary Resting CD4 Enhances HIV-1 Neisseria gonorrhoeae (2010) (0)
HIV-1 PLASMA RNA LEVELS CORRELATE WITH DISEASE PROGRESSION IN INFECTED CHILDREN. † 1079 (1996) (0)
Disease of the Month Highly Active Antiretroviral Therapy and the Epidemic of HIV ! End-Stage Renal Disease (2008) (0)
Hospital-Acquired Infections (1985) (0)
Erratum: Position statement, association of American physicians the imperative to invest in science has never been greater (Journal of Clinical Investigation (2014) 124:11 (5085) DOI:10.1172/JCI79469) (2014) (0)
Zoonotic infections: an emerging threat to human health. (2009) (0)
Persistent immunogenicity of integrase defective lentiviral vectors delivering membrane-tethered native-like HIV-1 envelope trimers (2022) (0)
Book Reviews (2005) (0)
Chapter 24 – Hepatitis B- and HIV-Related Renal Diseases (2008) (0)
T Lymphocytes + Primary CD4 Fibronectin, Increases HIV Infection of Superfibronectin, a Multimeric Form of (2000) (0)
Respiratory Viruses and Disease Association (2009) (0)

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