Mary Kearney
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American biologist
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Mary Kearneybiology Degrees
Biology
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Genetics
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Molecular Biology
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Biology
Mary Kearney's Degrees
- Bachelors Biology University of California, Berkeley
- Masters Biotechnology Stanford University
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Why Is Mary Kearney Influential?
(Suggest an Edit or Addition)According to Wikipedia, Mary F. Kearney is an American biologist. She is a senior scientist and head of the translational research section in the HIV dynamics and replication program at the National Cancer Institute. Education Kearney completed a B.A. and M.S. in biomedical science at Hood College. Her master's thesis was titled Determining the resistance profile of conocurvone, an early-stage inhibitor of HIV-1 replication. Her advisor was Luke Pallansch. Kearney received a Ph.D. in biology from Catholic University of America in 2007 under the direction of John Coffin, Sarah Palmer, and . Her thesis was titled HIV-1 evolution in recently infect patients. She received The Benedict T. DeCicco Award for Excellence in Graduate Research in 2008.
Mary Kearney's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy (2012) (1044)
- Specific HIV integration sites are linked to clonal expansion and persistence of infected cells (2014) (671)
- Single-strand specificity of APOBEC3G accounts for minus-strand deamination of the HIV genome (2004) (617)
- Multiple, Linked Human Immunodeficiency Virus Type 1 Drug Resistance Mutations in Treatment-Experienced Patients Are Missed by Standard Genotype Analysis (2005) (502)
- Treatment intensification does not reduce residual HIV-1 viremia in patients on highly active antiretroviral therapy (2009) (443)
- The Effect of Raltegravir Intensification on Low-level Residual Viremia in HIV-Infected Patients on Antiretroviral Therapy: A Randomized Controlled Trial (2010) (307)
- Clonally expanded CD4+ T cells can produce infectious HIV-1 in vivo (2016) (283)
- Histone Deacetylase Inhibitor Romidepsin Induces HIV Expression in CD4 T Cells from Patients on Suppressive Antiretroviral Therapy at Concentrations Achieved by Clinical Dosing (2014) (256)
- HIV-1 expression within resting CD4+ T cells after multiple doses of vorinostat. (2014) (229)
- Short-course raltegravir intensification does not reduce persistent low-level viremia in patients with HIV-1 suppression during receipt of combination antiretroviral therapy. (2010) (224)
- Immediate antiviral therapy appears to restrict resting CD4+ cell HIV-1 infection without accelerating the decay of latent infection (2012) (216)
- Lack of Detectable HIV-1 Molecular Evolution during Suppressive Antiretroviral Therapy (2014) (198)
- Proviruses with identical sequences comprise a large fraction of the replication-competent HIV reservoir (2017) (189)
- Majority of CD4+ T cells from peripheral blood of HIV-1–infected individuals contain only one HIV DNA molecule (2011) (187)
- Human Immunodeficiency Virus Type 1 Population Genetics and Adaptation in Newly Infected Individuals (2008) (175)
- HIV-1 persistence following extremely early initiation of antiretroviral therapy (ART) during acute HIV-1 infection: An observational study (2017) (171)
- B-108 Specific HIV integration sites are linked to clonal expansion and persistence of infected cells (2016) (148)
- Blinded, Multicenter Comparison of Methods To Detect a Drug-Resistant Mutant of Human Immunodeficiency Virus Type 1 at Low Frequency (2006) (125)
- A robust measure of HIV-1 population turnover within chronically infected individuals. (2004) (122)
- Single-cell analysis of HIV-1 transcriptional activity reveals expression of proviruses in expanded clones during ART (2017) (120)
- Single Cell Analysis of Lymph Node Tissue from HIV-1 Infected Patients Reveals that the Majority of CD4+ T-cells Contain One HIV-1 DNA Molecule (2013) (113)
- Low frequency nonnucleoside reverse-transcriptase inhibitor-resistant variants contribute to failure of efavirenz-containing regimens in treatment- experienced patients. (2010) (111)
- Origin of Rebound Plasma HIV Includes Cells with Identical Proviruses That Are Transcriptionally Active before Stopping of Antiretroviral Therapy (2015) (110)
- HIV Populations Are Large and Accumulate High Genetic Diversity in a Nonlinear Fashion (2013) (109)
- No Effect of Raltegravir Intensification on Viral Replication Markers in the Blood of HIV-1–Infected Patients Receiving Antiretroviral Therapy (2012) (107)
- Selection and persistence of non-nucleoside reverse transcriptase inhibitor-resistant HIV-1 in patients starting and stopping non-nucleoside therapy (2006) (104)
- Analysis of 454 sequencing error rate, error sources, and artifact recombination for detection of Low-frequency drug resistance mutations in HIV-1 DNA (2013) (103)
- Estimate of effective recombination rate and average selection coefficient for HIV in chronic infection (2011) (100)
- Failure to Confirm XMRV/MLVs in the Blood of Patients with Chronic Fatigue Syndrome: A Multi-Laboratory Study (2011) (96)
- HIV-1 Continues To Replicate and Evolve in Patients with Natural Control of HIV Infection (2010) (96)
- Improved Single-Copy Assays for Quantification of Persistent HIV-1 Viremia in Patients on Suppressive Antiretroviral Therapy (2014) (93)
- Frequent polymorphism at drug resistance sites in HIV-1 protease and reverse transcriptase (2008) (91)
- Low genetic diversity may be an Achilles heel of SARS-CoV-2 (2020) (77)
- HIV-1 in lymph nodes is maintained by cellular proliferation during antiretroviral therapy. (2019) (76)
- Comparison of standard PCR/cloning to single genome sequencing for analysis of HIV-1 populations. (2010) (70)
- Combined HIV-1 sequence and integration site analysis informs viral dynamics and allows reconstruction of replicating viral ancestors (2019) (68)
- No evidence of HIV replication in children on antiretroviral therapy. (2017) (62)
- SARS-CoV-2 Viremia is Associated with COVID-19 Severity and Predicts Clinical Outcomes. (2021) (56)
- Clones of infected cells arise early in HIV-infected individuals. (2019) (54)
- HIV-1 Viremia Not Suppressible By Antiretroviral Therapy Can Originate from Large T-Cell Clones Producing Infectious Virus (2020) (54)
- Therapeutic vaccination expands and improves the function of the HIV-specific memory T-cell repertoire. (2013) (52)
- Suppression of Viremia and Evolution of Human Immunodeficiency Virus Type 1 Drug Resistance in a Macaque Model for Antiretroviral Therapy (2007) (51)
- HIV evolution and diversity in ART-treated patients (2018) (50)
- Ongoing HIV Replication During ART Reconsidered (2017) (49)
- No evidence of ongoing HIV replication or compartmentalization in tissues during combination antiretroviral therapy: Implications for HIV eradication (2019) (48)
- Multiple Sources of Contamination in Samples from Patients Reported to Have XMRV Infection (2012) (45)
- Ultrasensitive single-genome sequencing: accurate, targeted, next generation sequencing of HIV-1 RNA (2016) (43)
- Therapeutic Vaccination With Dendritic Cells Loaded With Autologous HIV Type 1-Infected Apoptotic Cells. (2016) (43)
- Patterns of Human Immunodeficiency Virus Type 1 Recombination Ex Vivo Provide Evidence for Coadaptation of Distant Sites, Resulting in Purifying Selection for Intersubtype Recombinants during Replication (2010) (41)
- Immunogenicity of AGS-004 Dendritic Cell Therapy in Patients Treated During Acute HIV Infection. (2017) (41)
- Genetic Diversity of Simian Immunodeficiency Virus Encoding HIV-1 Reverse Transcriptase Persists in Macaques despite Antiretroviral Therapy (2010) (40)
- HIV Infected T Cells Can Proliferate in vivo Without Inducing Expression of the Integrated Provirus (2019) (38)
- Ex vivo activation of CD4+ T-cells from donors on suppressive ART can lead to sustained production of infectious HIV-1 from a subset of infected cells (2017) (37)
- Acquisition of tenofovir-susceptible, emtricitabine-resistant HIV despite high adherence to daily pre-exposure prophylaxis: a case report. (2018) (36)
- Low-frequency nevirapine (NVP)-resistant HIV-1 variants are not associated with failure of antiretroviral therapy in women without prior exposure to single-dose NVP. (2014) (33)
- Limited Nucleotide Changes in the Rev Response Element (RRE) during HIV-1 Infection Alter Overall Rev-RRE Activity and Rev Multimerization (2013) (32)
- Retrovirus Integration Database (RID): a public database for retroviral insertion sites into host genomes (2016) (31)
- Effector memory differentiation increases detection of replication-competent HIV-l in resting CD4+ T cells from virally suppressed individuals (2019) (30)
- Predictors of Residual Viraemia in Patients on Long-Term Suppressive Antiretroviral Therapy (2012) (25)
- Dynamic Shifts in the HIV Proviral Landscape During Long Term Combination Antiretroviral Therapy: Implications for Persistence and Control of HIV Infections (2020) (24)
- Review: influence of ART on HIV genetics (2015) (23)
- Ultrasensitive Allele-Specific PCR Reveals Rare Preexisting Drug-Resistant Variants and a Large Replicating Virus Population in Macaques Infected with a Simian Immunodeficiency Virus Containing Human Immunodeficiency Virus Reverse Transcriptase (2012) (23)
- Well-mixed plasma and tissue viral populations in RT-SHIV-infected macaques implies a lack of viral replication in the tissues during antiretroviral therapy (2015) (21)
- RT-SHIV subpopulation dynamics in infected macaques during anti-HIV therapy (2009) (20)
- Restricted Replication of Xenotropic Murine Leukemia Virus-Related Virus in Pigtailed Macaques (2012) (20)
- Intact HIV Proviruses Persist in Children Seven to Nine Years after Initiation of Antiretroviral Therapy in the First Year of Life (2019) (19)
- Integration in oncogenes plays only a minor role in determining the in vivo distribution of HIV integration sites before or during suppressive antiretroviral therapy (2021) (18)
- Mechanistic Analysis of the Broad Antiretroviral Resistance Conferred by HIV-1 Envelope Glycoprotein Mutations (2020) (14)
- Connection subdomain mutations in HIV-1 subtype-C treatment-experienced patients enhance NRTI and NNRTI drug resistance. (2013) (14)
- False-positive HIV PCR test following ex vivo lentiviral gene transfer treatment of X-linked severe combined immunodeficiency vector. (2014) (14)
- HIV Proviral Sequence Database (PSD): A New Public Database for Near Full-Length HIV Proviral Sequences and Their Meta-Analyses. (2020) (14)
- Therapeutic implications of ongoing alveolar viral replication in COVID-19 (2021) (14)
- PAPNC, a novel method to calculate nucleotide diversity from large scale next generation sequencing data. (2014) (13)
- Linked dual-class HIV resistance mutations are associated with treatment failure. (2019) (11)
- Amplifying and quantifying HIV-1 RNA in HIV infected individuals with viral loads below the limit of detection by standard clinical assays. (2011) (10)
- Nucleic Acid, Antibody, and Virus Culture Methods to Detect Xenotropic MLV-Related Virus in Human Blood Samples (2011) (10)
- Current status of xenotropic murine leukemia virus-related retrovirus in chronic fatigue syndrome and prostate cancer: reach for a scorecard, not a prescription pad. (2010) (9)
- Review: HIV-1 phylogeny during suppressive antiretroviral therapy (2019) (9)
- Low Frequency NNRTI-Resistant Variants Contribute to Failure of Efavirenz-Containing Regimens in Treatment-Experienced Patients (2010) (8)
- Plasma SARS-CoV-2 RNA levels as a biomarker of lower respiratory tract SARS-CoV-2 infection in critically ill patients with COVID-19. (2022) (8)
- Proceedings of the Frontiers of Retrovirology Conference 2016 (2016) (7)
- Engineered Bacteriophage T4 Nanoparticle as a Potential Targeted Activator of HIV-1 Latency in CD4+ Human T-cells (2021) (6)
- Phylogenetic inference for the study of within-host HIV-1 dynamics and persistence on antiretroviral therapy. (2019) (5)
- Lower pre-ART intra-participant HIV-1 pol diversity may not be associated with virologic failure in adults (2018) (5)
- Early Emergence and Long-Term Persistence of HIV-Infected T-Cell Clones in Children (2021) (4)
- Early Emergence and Long-Term Persistence of HIV-Infected T Cell Clones in Children (2020) (4)
- Prevalence of XMRV Nucleic Acid and Antibody in HIV-1-Infected Men and in Men at Risk for HIV-1 Infection (2011) (4)
- NanoHIV: A Bioinformatics Pipeline for Producing Accurate, Near Full-Length HIV Proviral Genomes Sequenced Using the Oxford Nanopore Technology (2021) (4)
- CpG Methylation Profiles of HIV-1 Proviral DNA in Individuals on ART (2021) (4)
- Erratum: Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy (2012) (3)
- Tracking HIV-1-Infected Cell Clones Using Integration Site-Specific qPCR (2021) (3)
- Intact HIV Proviruses Persist in Children 7-9 Years after Initiation of ART in the First Year of Life (2019) (3)
- P-A10 Accumulation and persistence of deleted HIV proviruses following prolonged ART (2018) (3)
- Use of Drug-Level Testing and Single-Genome Sequencing to Unravel a Case of HIV Seroconversion on PrEP. (2020) (3)
- Predictors of Residual Viremia in Patients on Long-term Suppressive Antiretroviral Therapy (2013) (3)
- HIV-1 Persistence in Children during Suppressive ART (2021) (2)
- HIVIntact: a python-based tool for HIV-1 genome intactness inference (2021) (2)
- New Approaches to Multi-Parametric HIV-1 Genetics Using Multiple Displacement Amplification: Determining the What, How, and Where of the HIV-1 Reservoir (2021) (2)
- Short Communication: HIV-DRLink: A Tool for Reporting Linked HIV-1 Drug Resistance Mutations in Large Single-Genome Data Sets Using the Stanford HIV Database (2020) (1)
- A Pre-Vaccination Baseline of SARS-CoV-2 Genetic Surveillance and Diversity in the United States (2022) (1)
- High-throughput sequencing of integrated HIV-1 reveals novel proviral structures (2019) (1)
- Review (2019) (1)
- Blinded, multicenter comparison of methods to detect low frequency drug-resistant HIV-1 variants (2006) (1)
- Use of Drug-level Testing and Single-genome Sequencing to Unravel a Case of Human Immunodeficiency Virus Seroconversion on Pre-exposure Prophylaxis (2020) (1)
- HIV drug resistance in various body compartments (2022) (1)
- Deep Sequencing Analysis of Individual HIV-1 Proviruses Reveals Frequent Asymmetric Long Terminal Repeats (2022) (1)
- HIV-DRLink: A Tool for Reporting Linked HIV-1 Drug Resistance Mutations in Large Single-Genome Datasets Using the Stanford HIV Database. (2020) (1)
- 2020 SARS-CoV-2 diversification in the United States: Establishing a pre-vaccination baseline (2021) (1)
- OP 1.3 – 00017 The fraction of cells with unspliced HIV RNA is not associated with plasma viremia (2022) (1)
- HIVIntact: a python-based tool for HIV-1 genome intactness inference (2021) (0)
- HIV Population Dynamics (2013) (0)
- Correction: The Effect of Raltegravir Intensification on Low-level Residual Viremia in HIV-Infected Patients on Antiretroviral Therapy: A Randomized Controlled Trial (2011) (0)
- Highlights from the Tenth International Workshop on HIV Persistence during Therapy, December 13-16, 2022, Miami, Florida-USA (2023) (0)
- 1 Title : Improved Single Copy Assays for Quantification of Persistent HIV-1 Viremia in 1 Patients on Suppressive Antiretroviral Therapy 2 3 (2014) (0)
- B-109 HIV Persistence During Combination Antiretroviral Therapy (2014) (0)
- Acquisition of tenofovir-susceptible HIV despite consistently high level adherence to daily PrEP as measured by plasma, dried blood spot (DBS) and segmental hair analysis: a case report (2019) (0)
- Proceedings of the Frontiers of Retrovirology Conference 2016 (2016) (0)
- Current HIV/SIV Reservoir Assays for Preclinical and Clinical Applications: Recommendations from the Experts 2022 NIAID Workshop Summary. (2023) (0)
- Updates on two public databases for studies of HIV persistence; the Retrovirus Integration Database (RID) and HIV Proviral Sequence Database (PSD) (2019) (0)
- Baseline Natural Killer and T Cell Populations Correlation with Virologic Outcome after Regimen Simplification to Atazanavir/Ritonavir Alone (ACTG 5201) (2014) (0)
- Patterns of Human Immunodeficiency Virus Type 1 Recombination Ex Vivo Provide Evidence for Coadaptation of Distant Sites, Resulting in Purifying Selection for Intersubtype Recombinants during Replication (cid:1) † (2010) (0)
- 1 HIV Populations are Large and Accumulate High Genetic Diversity in Nonlinear (2013) (0)
- Proviral landscape in children parallels adults and enables reservoir reconstruction (2019) (0)
- Ultrasensitive single-genome sequencing: accurate, targeted, next generation sequencing of HIV-1 RNA (2016) (0)
- Long-term persistence of HIV-infected cell clones in early treated children (2019) (0)
- HIV proviruses with identical sequences arise from cell expansion and infection by a common ancestor virus (2019) (0)
- A9 A method to obtain full-length HIV proviral sequences and their sites of integration (2019) (0)
- HIV-DRLink: A tool for detecting linked HIV-1 drug resistance mutations in next generation sequencing data (2019) (0)
- A-105 NO EVIDENCE FOR HIV REPLICATION IN LYMPH NODES DURING ART (2018) (0)
- A12 Modeling residual HIV replication and the emergence of drug resistance on ART (2019) (0)
- Integration in or Near Oncogenes Plays Only a Minor Role in Determining the in Vivo Distribution of HIV Integration Sites Before or During Suppressive Antiretroviral Therapy (2020) (0)
- Ultradeep analysis of pretherapy HIV predicts large and genetically complex reservoirs during antiretroviral therapy (2019) (0)
- Well-mixed plasma and tissue viral populations in RT-SHIV-infected macaques implies a lack of viral replication in the tissues during antiretroviral therapy (2015) (0)
- HIV viremia is the product of a small fraction of infected cells (2017) (0)
- Analysis of 454 sequencing error rate, error sources, and artifact recombination for detection of Low-frequency drug resistance mutations in HIV-1 DNA (2013) (0)
- PP 7.13 – 00090 Early evolution of HIV-1 from transmitted founders during acute infection (2022) (0)
- Retrovirus Integration Database (RID): a public database for retroviral insertion sites into host genomes (2016) (0)
- Ex vivo response to RMD in multiple longitudinal samples from the same donors. (2014) (0)
- HIV-1 in Lymph Nodes is Maintained by Cellular Proliferation During Antiretroviral 1 Therapy 2 3 (2019) (0)
- HIV evolution and diversity in ART-treated patients (2018) (0)
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