Mary Jeanne Kreek | Academic Influence

Mary Jeanne Kreek's AcademicInfluence.com Rankings

Mary Jeanne Kreek

Biology

#2968

World Rank

#4612

Historical Rank

#1261

USA Rank

Neuroscience

#581

World Rank

#606

Historical Rank

#168

USA Rank

biology Degrees

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Biology

Mary Jeanne Kreek's Degrees

Doctorate Medicine Columbia University

Why Is Mary Jeanne Kreek Influential?

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According to Wikipedia, Mary Jeanne Kreek was an American neurobiologist specializing in the study and treatment of addiction. She is best known for her work with Marie Nyswander and Dr. Vincent Dole in the development of methadone therapy for heroin addiction.

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Mary Jeanne Kreek's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Single-nucleotide polymorphism in the human mu opioid receptor gene alters beta-endorphin binding and activity: possible implications for opiate addiction. (1998) (1071)
Genetic influences on impulsivity, risk taking, stress responsivity and vulnerability to drug abuse and addiction (2005) (995)
Stress, dysregulation of drug reward pathways, and the transition to drug dependence. (2007) (835)
Drug dependence: stress and dysregulation of brain reward pathways. (1998) (624)
Effective medical treatment of opiate addiction (1998) (580)
Stress-induced cocaine craving and hypothalamic-pituitary-adrenal responses are predictive of cocaine relapse outcomes. (2006) (501)
Naltrexone decreases craving and alcohol self-administration in alcohol-dependent subjects and activates the hypothalamo–pituitary–adrenocortical axis (2002) (479)
1-year retention and social function after buprenorphine-assisted relapse prevention treatment for heroin dependence in Sweden: a randomised, placebo-controlled trial (2003) (424)
Pharmacogenetics and Human Molecular Genetics of Opiate and Cocaine Addictions and Their Treatments (2005) (358)
Hypothalamic-pituitary-adrenal axis and sympatho-adreno-medullary responses during stress-induced and drug cue-induced cocaine craving states (2003) (345)
Common liability to addiction and "gateway hypothesis": theoretical, empirical and evolutionary perspective. (2012) (334)
Effects of adrenal sensitivity, stress- and cue-induced craving, and anxiety on subsequent alcohol relapse and treatment outcomes. (2011) (320)
HIV-1 Infection Among Intravenous Drug Users in Manhattan, New York City, From 1977 Through 1987 (1989) (282)
Medical safety and side effects of methadone in tolerant individuals. (1973) (235)
Narcotic blockade. (1966) (231)
Repeated cocaine administration upregulates kappa and mu, but not delta, opioid receptors. (1994) (229)
Increased Attributable Risk Related to a Functional μ-Opioid Receptor Gene Polymorphism in Association with Alcohol Dependence in Central Sweden (2005) (227)
'Binge' cocaine administration induces a sustained increase of prodynorphin mRNA in rat caudate-putamen. (1993) (224)
The single nucleotide polymorphism A118G alters functional properties of the human mu opioid receptor (2007) (213)
Rifampin-induced methadone withdrawal. (1976) (212)
Effects of extended access to high versus low cocaine doses on self-administration, cocaine-induced reinstatement and brain mRNA levels in rats (2004) (200)
Opiate addiction and cocaine addiction: underlying molecular neurobiology and genetics. (2012) (187)
Altered methadone pharmacokinetics in methadone-maintained pregnant women. (1985) (185)
Effects of the plant-derived hallucinogen salvinorin A on basal dopamine levels in the caudate putamen and in a conditioned place aversion assay in mice: agonist actions at kappa opioid receptors (2005) (184)
Natural killer cell activity and lymphocyte subsets in parenteral heroin abusers and long-term methadone maintenance patients. (1989) (173)
Frequency of recent cocaine and alcohol use affects drug craving and associated responses to stress and drug-related cues (2005) (167)
κ-opioid receptor/dynorphin system: genetic and pharmacotherapeutic implications for addiction (2012) (165)
Predictable individual differences in the initiation of cocaine self-administration by rats under extended-access conditions are dose-dependent (2001) (157)
Time course of the development of behavioral sensitization and dopamine receptor up-regulation during binge cocaine administration. (1994) (154)
Chronic cocaine alters brain mu opioid receptors (1992) (154)
Opioid receptor and peptide gene polymorphisms: potential implications for addictions. (2000) (147)
ABCB1 (MDR1) genetic variants are associated with methadone doses required for effective treatment of heroin dependence. (2008) (147)
Corticotropin-releasing factor and type 1 corticotropin-releasing factor receptor messenger RNAs in rat brain and pituitary during "binge"-pattern cocaine administration and chronic withdrawal. (1996) (142)
Increased OPRM1 DNA Methylation in Lymphocytes of Methadone-Maintained Former Heroin Addicts (2009) (141)
The Kreek-McHugh-Schluger-Kellogg scale: a new, rapid method for quantifying substance abuse and its possible applications. (2003) (140)
The genetics of the opioid system and specific drug addictions (2012) (140)
Reactivity to laboratory stress provocation predicts relapse to cocaine. (2010) (139)
Distribution of nociceptin/orphanin FQ receptor transcript in human central nervous system and immune cells (1998) (139)
Opiates, opioids and addiction. (1996) (137)
Treatment of opioid‐induced constipation with oral naloxone: A pilot study (1992) (134)
Rationale for maintenance pharmacotherapy of opiate dependence. (1992) (132)
Nalmefene Induced Elevation in Serum Prolactin in Normal Human Volunteers: Partial Kappa Opioid Agonist Activity? (2005) (131)
NALOXONE, A SPECIFIC OPIOID ANTAGONIST, REVERSES CHRONIC IDIOPATHIC CONSTIPATION (1983) (130)
Long-term methadone maintenance therapy: effects on liver function. (1972) (129)
Corrected-QT intervals as related to methadone dose and serum level in methadone maintenance treatment (MMT) patients: a cross-sectional study. (2007) (125)
HEROIN ADDICTION AND RELATED CLINICAL PROBLEMS (2002) (125)
History and current status of opioid maintenance treatments: blending conference session. (2002) (120)
Effect of the endogenous κ opioid agonist dynorphin A(1–17) on cocaine-evoked increases in striatal dopamine levels and cocaine-induced place preference in C57BL/6J mice (2004) (118)
Regulation of kappa opioid receptor mRNA in the rat brain by "binge' pattern cocaine administration and correlation with preprodynorphin mRNA. (1996) (115)
Methadone use in patients with chronic renal disease. (1980) (111)
Mu opioid receptor and orexin/hypocretin mRNA levels in the lateral hypothalamus and striatum are enhanced by morphine withdrawal. (2006) (111)
Quantitation of preproenkephalin mRNA levels in brain regions from male Fischer rats following chronic cocaine treatment using a recently developed solution hybridization assay. (1992) (111)
Phenytoin-induced methadone withdrawal. (1981) (110)
Methadone plasma level: sustained by a reservoir of drug in tissue. (1973) (108)
The plant-derived hallucinogen, salvinorin A, produces κ-opioid agonist-like discriminative effects in rhesus monkeys (2004) (108)
CYP2B6 SNPs are associated with methadone dose required for effective treatment of opioid addiction (2013) (105)
Opioid receptor imaging with positron emission tomography and [(18)F]cyclofoxy in long-term, methadone-treated former heroin addicts. (2000) (104)
Neuropathic and chronic pain stimuli downregulate central mu-opioid and dopaminergic transmission. (2010) (104)
Redefinition of the human kappa opioid receptor gene (OPRK1) structure and association of haplotypes with opiate addiction. (2004) (101)
Chronic administration of a cocaine "binge" alters basal extracellular levels in male rats: an in vivo microdialysis study. (1995) (101)
Search for genetic markers and functional variants involved in the development of opiate and cocaine addiction and treatment (2010) (101)
Cocaine, dopamine and the endogenous opioid system. (1996) (101)
Treatment of opioid-induced constipation with oral naloxone: a pilot study. (1993) (99)
μ-, δ- and κ-opioid receptor populations are differentially altered in distinct areas of postmortem brains of Alzheimer’s disease patients (2001) (97)
Nalmefene causes greater hypothalamic-pituitary-adrenal axis activation than naloxone in normal volunteers: implications for the treatment of alcoholism. (1998) (96)
Circadian rhythms and levels of beta-endorphin, ACTH, and cortisol during chronic methadone maintenance treatment in humans. (1983) (96)
Association of the OPRM1 Variant rs1799971 (A118G) with Non-Specific Liability to Substance Dependence in a Collaborative de novo Meta-Analysis of European-Ancestry Cohorts (2016) (94)
The frequency of cocaine administration impacts cocaine-induced receptor alterations (2001) (94)
Female sex steroids and cholestasis. (1987) (93)
Estrous cycle differences in cocaine-induced stereotypic and locomotor behaviors in Fischer rats (1999) (92)
Pharmacotherapy in the Treatment of Addiction: Methadone (2010) (91)
Involvement of Arginine Vasopressin and V1b Receptor in Heroin Withdrawal and Heroin Seeking Precipitated by Stress and by Heroin (2008) (91)
Genotype patterns that contribute to increased risk for or protection from developing heroin addiction (2008) (91)
Psychiatric comorbidity in methadone maintained patients. (1998) (89)
Acute tolerance to the dopamine response induced by a binge pattern of cocaine administration in male rats: an in vivo microdialysis study. (1994) (88)
Altered HPA Axis Responsivity to Metyrapone Testing in Methadone Maintained Former Heroin Addicts with Ongoing Cocaine Addiction (2001) (87)
Critical issues in the treatment of hepatitis C virus infection in methadone maintenance patients. (2008) (83)
The Nociceptin/Orphanin FQ Receptor Agonist Ro 64-6198 Reduces Alcohol Self-Administration and Prevents Relapse-Like Alcohol Drinking (2007) (82)
Chronic opioid antagonist administration upregulates mu opioid receptor binding without altering mu opioid receptor mRNA levels. (1995) (81)
Opiate and Cocaine Addictions: Challenge for Pharmacotherapies (1997) (81)
Potentially functional polymorphism in the promoter region of prodynorphin gene may be associated with protection against cocaine dependence or abuse. (2002) (80)
The medical status of methadone maintenance patients in treatment for 11-18 years. (1993) (80)
Naltrexone biotransformation and incidence of subjective side effects: a preliminary study. (1997) (78)
Chronic repeated cocaine administration increases dopamine D1 receptor-mediated signal transduction. (1996) (78)
Hypothalamic-Pituitary-Adrenocortical (HPA) Axis Response and Biotransformation of Oral Naltrexone: Preliminary Examination of Relationship to Family History of Alcoholism (2002) (78)
Breaking Barriers in the Genomics and Pharmacogenetics of Drug Addiction (2010) (78)
Gender differences in cardiovascular and corticoadrenal response to stress and drug cues in cocaine dependent individuals (2006) (77)
Chronic repeated cocaine administration alters basal and opioid‐regulated adenylyl cyclase activity (1993) (77)
Methadone disposition during the perinatal period in humans. (1979) (75)
Stereoselective disposition of methadone in man. (1979) (75)
Behavioral and Neurochemical Changes Induced by Oxycodone Differ Between Adolescent and Adult Mice (2009) (74)
Something of value: the introduction of contingency management interventions into the New York City Health and Hospital Addiction Treatment Service. (2005) (73)
Reduced hypothalamic POMC and anterior pituitary CRF1 receptor mRNA levels after acute, but not chronic, daily "binge" intragastric alcohol administration. (2000) (72)
Genes associated with addiction (2007) (71)
Hepatitis D virus and human immunodeficiency virus antibodies in parenteral drug abusers who are hepatitis B surface antigen positive. (1988) (71)
Effects of cocaine place conditioning, chronic escalating-dose “binge” pattern cocaine administration and acute withdrawal on orexin/hypocretin and preprodynorphin gene expressions in lateral hypothalamus of Fischer and Sprague–Dawley rats (2008) (70)
Ethnic diversity of DNA methylation in the OPRM1 promoter region in lymphocytes of heroin addicts (2010) (70)
A Functional Haplotype Implicated in Vulnerability to Develop Cocaine Dependence is Associated with Reduced PDYN Expression in Human Brain (2009) (69)
Effects of gender and cigarette smoking on reactivity to psychological and pharmacological stress provocation (2008) (68)
Determination of Salvinorin A in body fluids by high performance liquid chromatography-atmospheric pressure chemical ionization. (2005) (68)
Cocaine abuse sharply reduced in an effective methadone maintenance program. (1999) (67)
Analyses of methadone and other drugs in maternal and neonatal body fluids: use in evaluation of symptoms in a neonate of mother maintained on methadone. (1974) (67)
Opiate and cocaine addiction: from bench to clinic and back to the bench. (2009) (67)
Former heroin addicts with or without a history of cocaine dependence are more impulsive than controls. (2012) (66)
Pharmacotherapy of addictions (2002) (66)
Effect of the endogenous kappa opioid agonist dynorphin A(1-17) on cocaine-evoked increases in striatal dopamine levels and cocaine-induced place preference in C57BL/6J mice. (2004) (66)
QT Interval Screening in Methadone Maintenance Treatment: Report of a SAMHSA Expert Panel (2011) (66)
One-Year and Cumulative Retention as Predictors of Success in Methadone Maintenance Treatment: A Comparison of Two Clinics in the United States and Israel (2008) (65)
Nicotine addiction: insights from recent animal studies (2002) (64)
Opioid receptors: Some perspectives from early studies of their role in normal physiology, stress responsivity, and in specific addictive diseases (1996) (64)
Idiopathic cholestasis of pregnancy. (1967) (64)
Detection of single nucleotide polymorphisms of the human mu opioid receptor gene by hybridization or single nucleotide extension on custom oligonucleotide gelpad microchips: potential in studies of addiction. (2000) (64)
Association analysis of polymorphisms in serotonin 1B receptor (HTR1B) gene with heroin addiction: a comparison of molecular and statistically estimated haplotypes (2006) (63)
Prodynorphin, proenkephalin and κ opioid receptor mRNA responses to acute “binge” cocaine (1997) (63)
Increased AMPA GluR1 receptor subunit labeling on the plasma membrane of dendrites in the basolateral amygdala of rats self‐administering morphine (2005) (62)
Unconditioned Behavioral Effects of the Powerful κ-Opioid Hallucinogen Salvinorin A in Nonhuman Primates: Fast Onset and Entry into Cerebrospinal Fluid (2009) (62)
Acute “binge” cocaine increases mu-opioid receptor mRNA levels in areas of the rat mesolimbic mesocortical dopamine system (1999) (62)
Effects of cocaine self-administration on plasma corticosterone and prolactin in rats. (2000) (62)
Effects of High-Dose Methadone Maintenance on Cocaine Place Conditioning, Cocaine Self-Administration, and Mu-Opioid Receptor mRNA Expression in the Rat Brain (2006) (60)
Effects of “Binge” Pattern Cocaine on Stereotypy and Locomotor Activity in C57BL/6J and 129/J Mice (1998) (60)
Effect of the κ opioid agonist R-84760 on cocaine-induced increases in striatal dopamine levels and cocaine-induced place preference in C57BL/6J mice (2004) (60)
METABOLIC INTERACTIONS BETWEEN OPIATES AND ALCOHOL * (1981) (60)
Increased CRH mRNA levels in the rat amygdala during short-term withdrawal from chronic 'binge' cocaine. (2003) (58)
Neuroendocrine alterations in a high-dose, extended-access rat self-administration model of escalating cocaine use (2003) (58)
High Methadone Dose Significantly Reduces Cocaine Use in Methadone Maintenance Treatment (MMT) Patients (2006) (58)
Sustained Withdrawal Allows Normalization of In Vivo [11C]N-Methylspiperone Dopamine D2 Receptor Binding after Chronic Binge Cocaine: A Positron Emission Tomography Study in Rats (1998) (57)
Lethal methadone intoxications in Geneva, Switzerland, from 1994 to 1998. (2000) (57)
Corticotropin-Releasing Factor Testing Reveals a Dose-Dependent Difference in Methadone Maintained Vs Control Subjects (2003) (57)
A preliminary study of beta endorphin during chronic naltrexone maintenance treatment in ex-opiate addicts. (1986) (56)
Novel and previously reported single-nucleotide polymorphisms in the human 5-HT(1B) receptor gene: no association with cocaine or alcohol abuse or dependence. (2001) (56)
Sticky-End PCR : New Method for Subcloning (56)
Drug-induced and genetic alterations in stress-responsive systems: Implications for specific addictive diseases (2010) (55)
Neuroendocrine-Related Effects of Long-Term, ‘Binge’ Cocaine Administration: Diminished Individual Differences in Stress-Induced Corticosterone Response (1998) (54)
Alterations in hypothalamic–pituitary–adrenal axis activity and in levels of proopiomelanocortin and corticotropin-releasing hormone-receptor 1 mRNAs in the pituitary and hypothalamus of the rat during chronic ‘binge’ cocaine and withdrawal (2003) (54)
Genome-wide association study identifies genes that may contribute to risk for developing heroin addiction (2010) (54)
Acute intermittent morphine increases preprodynorphin and kappa opioid receptor mRNA levels in the rat brain. (1999) (54)
PET imaging of leptin biodistribution and metabolism in rodents and primates. (2009) (53)
Acquired immunodeficiency syndrome and infection with hepatitis viruses in individuals abusing drugs by injection. (1986) (53)
Cocaine Self-Administration in Mice Is Inversely Related to Phosphorylation at Thr34 (Protein Kinase A Site) and Ser130 (Kinase CK1 Site) of DARPP-32 (2006) (53)
Cortisol levels during chronic naltrexone maintenance treatment in ex-opiate addicts (1986) (52)
Cocaine injection and ethnicity in parenteral drug users during the early years of the human immunodeficiency virus (hiv) epidemic in new york city (1989) (52)
Sex-specific dissociations in autonomic and HPA responses to stress and cues in alcohol-dependent patients with cocaine abuse. (2009) (52)
TPH2 and TPH1: Association of Variants and Interactions with Heroin Addiction (2008) (52)
Drug Addiction and Stress‐Response Genetic Variability: Association Study in African Americans (2014) (51)
Involvement of arginine vasopressin and V1b receptor in alcohol drinking in Sardinian alcohol-preferring rats. (2011) (51)
REDUCTION OF SERUM-UNCONJUGATED-BILIRUBIN WITH PHENOBARBITONE IN ADULT CONGENITAL NON-HÆMOLYTIC UNCONJUGATED HYPERBILIRUBINÆMIA (1968) (51)
Recurrent cholestatic jaundice of pregnancy with demonstrated estrogen sensitivity. (1967) (51)
Effects of Salvinorin A, a κ-Opioid Hallucinogen, on a Neuroendocrine Biomarker Assay in Nonhuman Primates with High κ-Receptor Homology to Humans (2007) (51)
Optimizing primer–probe design for fluorescent PCR (2003) (51)
Conditioned place preference after single doses or “binge” cocaine in C57BL/6J and 129/J mice (2002) (51)
Stress-related genes and heroin addiction: A role for a functional FKBP5 haplotype (2014) (50)
Using methadone effectively: achieving goals by application of laboratory, clinical, and evaluation research and by development of innovative programs. (1991) (50)
Modulation of CRF-R1 mRNA in rat anterior pituitary by dexamethasone: Correlation with POMC mRNA (1996) (50)
Common and specific liability to addiction: approaches to association studies of opioid addiction. (2012) (50)
Region-Specific Changes in the Subcellular Distribution of AMPA Receptor GluR1 Subunit in the Rat Ventral Tegmental Area after Acute or Chronic Morphine Administration (2008) (49)
Hypothalamic-pituitary-adrenal activity and pro-opiomelanocortin mRNA levels in the hypothalamus and pituitary of the rat are differentially modulated by acute intermittent morphine with or without water restriction stress. (1999) (49)
Suppressed Prolactin Response to Dynorphin A1–13 in Methadone-Maintained Versus Control Subjects (2003) (49)
Effect of severe alcoholic liver disease on the disposition of methadone in maintenance patients. (1985) (48)
Mouse Model of the OPRM1 (A118G) Polymorphism: Differential Heroin Self-Administration Behavior Compared with Wild-Type Mice (2015) (48)
Human behavioral pharmacology, past, present, and future: symposium presented at the 50th annual meeting of the Behavioral Pharmacology Society (2010) (48)
Neurobiology of addictive behaviors and its relationship to methadone maintenance. (2000) (48)
Opioid interactions with alcohol. (1984) (47)
Oxycodone-induced conditioned place preference and sensitization of locomotor activity in adolescent and adult mice (2013) (47)
Methadone—Disulfiram Interaction During Methadone Maintenance (1980) (47)
The discriminative effects of the κ-opioid hallucinogen salvinorin A in nonhuman primates: dissociation from classic hallucinogen effects (2010) (46)
Community-dwelling cocaine-dependent men and women respond differently to social stressors versus cocaine cues (2010) (46)
Effect of chronic naltrexone and methadone administration on brain immunoreactive beta-endorphin in the rat. (1983) (46)
Extended access oxycodone self-administration and neurotransmitter receptor gene expression in the dorsal striatum of adult C57BL/6 J mice (2014) (46)
Association of polymorphisms of the cannabinoid receptor (CNR1) and fatty acid amide hydrolase (FAAH) genes with heroin addiction: impact of long repeats of CNR1 (2010) (46)
Behavioral stereotypies induced by `binge' cocaine administration are independent of drug-induced increases in corticosterone levels (1997) (45)
Tissue-specific DNA methylation of the human prodynorphin gene in post-mortem brain tissues and PBMCs (2010) (45)
Current status of opioid addiction treatment and related preclinical research (2019) (44)
Salvinorin A, a kappa-opioid receptor agonist hallucinogen: pharmacology and potential template for novel pharmacotherapeutic agents in neuropsychiatric disorders (2015) (44)
Corticotropin-releasing factor decreases vasogenic brain edema. (1996) (44)
Amygdalar vasopressin mRNA increases in acute cocaine withdrawal: Evidence for opioid receptor modulation (2005) (43)
Effects of acute “binge” cocaine on preprodynorphin, preproenkephalin, proopiomelanocortin, and corticotropin‐releasing hormone receptor mRNA levels in the striatum and hypothalamic–pituitary–adrenal axis of mu‐opioid receptor knockout mice (2002) (43)
Chronic administration of morphine is associated with a decrease in surface AMPA GluR1 receptor subunit in dopamine D1 receptor expressing neurons in the shell and non-D1 receptor expressing neurons in the core of the rat nucleus accumbens (2008) (43)
Pharmacokinetics of the plant-derived kappa-opioid hallucinogen salvinorin A in nonhuman primates. (2005) (42)
Effects of the androgenic anabolic steroid, nandrolone decanoate, on adrenocorticotropin hormone, corticosterone and proopiomelanocortin, corticotropin releasing factor (CRF) and CRF receptor1 mRNA levels in the hypothalamus, pituitary and amygdala of the rat (2000) (42)
Involvement of dynorphin and kappa opioid receptor in yohimbine‐induced reinstatement of heroin seeking in rats (2013) (42)
Variable dose naltrexone-induced hypothalamic-pituitary-adrenal stimulation in abstinent alcoholics: a preliminary study. (1999) (42)
CHRONIC USE OF OPIOIDS AND ANTIPSYCHOTIC DRUGS: SIDE EFFECTS, EFFECTS ON ENDOGENOUS OPIOIDS, AND TOXICITY * (1982) (42)
Mu-, delta- and kappa-opioid receptor populations are differentially altered in distinct areas of postmortem brains of Alzheimer's disease patients. (2001) (42)
Extreme marginalization: addiction and other mental health disorders, stigma, and imprisonment (2011) (42)
A C17T polymorphism in the mu opiate receptor is associated with quantitative measures of drug use in African American women (2012) (41)
Association of genetic variation in pharmacodynamic factors with methadone dose required for effective treatment of opioid addiction. (2013) (41)
Ovarian hormone replacement affects cocaine-induced behaviors in ovariectomized female rats (2000) (41)
Response to corticotropin-releasing hormone infusion in cocaine-dependent individuals. (2009) (41)
Repeated Administration of Opra Kappa (LY2456302), a Novel, Short-Acting, Selective KOP-r Antagonist, in Persons with and without Cocaine Dependence (2017) (40)
Hepatic extraction of long- and short-acting narcotics in the isolated perfused rabbit liver. (1978) (40)
Overlapping Dopaminergic Pathway Genetic Susceptibility to Heroin and Cocaine Addictions in African Americans (2015) (40)
Differential biotransformation of dynorphin A(1–17) and dynorphin A(1–13) peptides in human blood, ex vivo (1996) (40)
Effect of acute binge cocaine on levels of extracellular dopamine in the caudate putamen and nucleus accumbens in male C57BL/6J and 129/J mice (2001) (40)
Effect of chronic “binge cocaine” on basal levels and cocaine‐induced increases of dopamine in the caudate putamen and nucleus accumbens of C57BL/6J and 129/J mice (2003) (39)
Dose escalation and dose preference in extended-access heroin self-administration in Lewis and Fischer rats (2012) (39)
Quantitation of dopamine transporter mrna in the rat brain: Mapping, effects of “binge” cocaine administration and withdrawal (1997) (39)
Alterations of expression of inflammation/immune-related genes in the dorsal and ventral striatum of adult C57BL/6J mice following chronic oxycodone self-administration: a RNA sequencing study (2017) (39)
Methadone-maintained patients. Effect of methadone on plasma testosterone, FSH, LH, and prolactin. (1974) (39)
Mu opioid receptor knockdown in the substantia nigra/ventral tegmental area by synthetic small interfering RNA blocks the rewarding and locomotor effects of heroin (2009) (39)
Genetics of Opiate Addiction (2014) (39)
Persistent Increase in Hypothalamic Arginine Vasopressin Gene Expression During Protracted Withdrawal from Chronic Escalating-Dose Cocaine in Rodents (2011) (39)
Chronic food restriction and streptozotocin-induced diabetes differentially alter prodynorphin mRNA levels in rat brain regions. (1997) (39)
Steady-state methadone blocks cocaine seeking and cocaine-induced gene expression alterations in the rat brain (2009) (38)
Antiallodynic Effects of Loperamide and Fentanyl against Topical Capsaicin-Induced Allodynia in Unanesthetized Primates (2004) (38)
Dose preference and dose escalation in extended-access cocaine self-administration in Fischer and Lewis rats (2010) (38)
Self administration of oxycodone alters synaptic plasticity gene expression in the hippocampus differentially in male adolescent and adult mice (2015) (38)
Chromatin alterations in response to forced swimming underlie increased prodynorphin transcription (2012) (38)
Steady-dose and escalating-dose “binge” administration of cocaine alter expression of behavioral stereotypy and striatal preprodynorphin mRNA levels in rats (2005) (38)
Effect of clonidine pretreatment on naloxone-precipitated opiate withdrawal. (1996) (38)
Effects of handling and vehicle injections on adrenocorticotropic and corticosterone concentrations in Sprague-Dawley compared with Lewis rats. (2015) (38)
Methadone-maintained former heroin addicts, including those who are anti-HIV-1 seropositive, comply with and respond to hepatitis B vaccination. (1999) (38)
“Effects of the novel relatively short-acting kappa opioid receptor antagonist LY2444296 in behaviors observed after chronic extended-access cocaine self-administration in rats” (2017) (37)
Hepatic cirrhosis in young adults: association with adolescent onset of alcohol and parenteral heroin abuse. (1985) (37)
Blockade of alcohol escalation and “relapse” drinking by pharmacological FAAH inhibition in male and female C57BL/6J mice (2017) (37)
Nociceptin in vitro biotransformation in human blood (1996) (37)
Beta endorphin levels in CSF during methadone maintenance. (1987) (36)
Locomotion, stereotypy, and dopamine D1 receptors after chronic “binge” cocaine in C57BL/6J and 129/J mice (2003) (36)
Anti-neoplastic properties of human corticotropin releasing factor: involvement of the nitric oxide pathway. (1998) (36)
Beta endorphin levels during heroin, methadone, buprenorphine, and naloxone challenges: Preliminary findings (1992) (36)
Catechol‐O‐methyltransferase (COMT) gene variants: Possible association of the Val158Met variant with opiate addiction in hispanic women (2008) (36)
Steady-state methadone in rats does not change mRNA levels of corticotropin-releasing factor, its pituitary receptor or proopiomelanocortin. (1996) (36)
Dynorphin A(1–17) biotransformation in striatum of freely moving rats using microdialysis and matrix‐assisted laser desorption/ionization mass spectrometry (2003) (36)
Matrix-Assisted Laser Desorption Mass Spectrometry of Biotransformation Products of Dynorphin A in Vitro (1994) (35)
GLUCURONIDE FORMATION IN THE TRANSPORT OF TESTOSTERONE AND ANDROSTENEDIONE BY RAT INTESTINE. (1963) (35)
Effects of dynorphin A(1–13) on opiate withdrawal in humans (1998) (35)
Sex differences in responsiveness to the prescription opioid oxycodone in mice (2016) (35)
Hepatitis C Virus and Human Immunodeficiency Virus-1 Co-Infection in Former Heroin Addicts in Methadone Maintenance Treatment (2002) (35)
Tissue plasminogen activator modulates the cellular and behavioral response to cocaine (2009) (34)
Effects of Ethinylestradiol-Induced Cholestasis on Bile Flow and Biliary Excretion of Estradiol and Estradiol Glucuronide by the Rat∗ (1969) (34)
Subject‐regulated dosing alters morphine self‐administration behavior and morphine‐stimulated [35S]GTPγS binding (2003) (33)
Effect of Endogenous Cortisol Levels on Natural Killer Cell Activity in Healthy Humans (1998) (33)
GR89,696: A Potent κ-Opioid Agonist with Subtype Selectivity in Rhesus Monkeys (2001) (33)
Signaling properties of structurally diverse kappa opioid receptor ligands: towards in vitro models of in vivo responses. (2019) (33)
Methadone Medical Maintenance: An Early 21st-Century Perspective (2015) (33)
In vitro studies of the effect of methadone on natural killer cell activity. (1990) (32)
Mu‐opioid receptor A118G polymorphism in healthy volunteers affects hypothalamic–pituitary–adrenal axis adrenocorticotropic hormone stress response to metyrapone (2013) (32)
Involvement of Endocannabinoids in Alcohol "Binge" Drinking: Studies of Mice with Human Fatty Acid Amide Hydrolase Genetic Variation and After CB1 Receptor Antagonists. (2016) (32)
Biological clock: Biological clocks may modulate drug addiction (2005) (32)
Long-Term Pharmacotherapy for Opiate (Primarily Heroin) Addiction: Opioid Agonists (1996) (32)
Association of polymorphisms in the melanocortin receptor type 2 (MC2R, ACTH receptor) gene with heroin addiction (2008) (32)
Immediate withdrawal from chronic "binge" cocaine administration increases mu-opioid receptor mRNA levels in rat frontal cortex. (2005) (32)
Evolving perspectives on neurobiological research on the addictions: celebration of the 30th anniversary of NIDA (2004) (32)
Chronic escalating cocaine exposure, abstinence/withdrawal, and chronic re-exposure: Effects on striatal dopamine and opioid systems in C57BL/6J mice (2013) (32)
Haplotype block structure of the genomic region of the mu opioid receptor gene (OPRM1) (2010) (31)
Contrasting prevalence of delta hepatitis markers in parenteral drug abusers with and without AIDS. (1990) (31)
Effect of the kappa opioid agonist R-84760 on cocaine-induced increases in striatal dopamine levels and cocaine-induced place preference in C57BL/6J mice. (2004) (31)
Sex, Drugs, and Infections Among Youth: Parenterally and Sexually Transmitted Diseases in a High‐Risk Neighborhood (1997) (31)
Alcohol: A stimulant activating brain stress responsive systems with persistent neuroadaptation (2014) (31)
Downregulation of 5‐HT1A receptors in rat hypothalamus and dentate gyrus after “binge” pattern cocaine administration (1998) (30)
Stress responsivity, addiction, and a functional variant of the human mu-opioid receptor gene. (2007) (30)
Effects of E-2078, a stable dynorphin A(1–8) analog, on sedation and serum prolactin levels in rhesus monkeys (1999) (30)
Prodynorphin, proenkephalin and kappa opioid receptor mRNA responses to acute "binge" cocaine. (1997) (30)
Effects of Chronic ‘Binge’ Cocaine Administration on Plasma ACTH and Corticosterone Levels in Mice Deficient in DARPP-32 (1999) (30)
Structurally Related Kappa Opioid Receptor Agonists with Substantial Differential Signaling Bias: Neuroendocrine and Behavioral Effects in C57BL6 Mice (2018) (30)
Decreased plasma membrane targeting of NMDA‐NR1 receptor subunit in dendrites of medial nucleus tractus solitarius neurons in rats self‐administering morphine (2004) (30)
Effects of salvinorin A, a kappa-opioid hallucinogen, on a neuroendocrine biomarker assay in nonhuman primates with high kappa-receptor homology to humans. (2007) (29)
Topical Capsaicin-Induced Allodynia in Unanesthetized Primates: Pharmacological Modulation (2003) (29)
Hepatitis B serologic studies in narcotic users with chronic liver disease. (1981) (28)
Heroin-induced locomotor activity and conditioned place preference in C57BL/6J and 129P3/J mice (2008) (28)
Narcotic blockade--a medical technique for stopping heroin use by addicts. (1966) (28)
Downregulation of κ‐opioid receptors in basolateral amygdala and septum of rats withdrawn for 14 days from an escalating dose “binge” cocaine administration paradigm (2007) (28)
Oxycodone Self-Administration Induces Alterations in Expression of Integrin, Semaphorin and Ephrin Genes in the Mouse Striatum (2018) (28)
“Skinny needle” cholangiography—Results of a pilot study of a voluntary prospective method for gathering risk data on new procedures (1980) (28)
Ethanol and methadone in man: A possible drug interaction (1978) (28)
Carbon dioxide-induced anesthesia results in a rapid increase in plasma levels of vasopressin. (2009) (28)
Semisynthetic neoclerodanes as kappa opioid receptor probes. (2012) (28)
Replication of an effective opiate addiction pharmacotherapeutic treatment model : Minimal need for modification in a different country (2000) (28)
Effects of voluntary alcohol drinking on corticotropin-releasing factor and preprodynorphin mRNA levels in the central amygdala of Sardinian alcohol-preferring rats (2013) (28)
Acute ‘binge’ cocaine administration elevates dynorphin mRNA in the caudate putamen of C57BL/6J but not 129/J mice (2003) (27)
In vivo and in vitro studies of opiates and cellular immunity in narcotic addicts. (1991) (27)
Bidirectional translational research: Progress in understanding addictive diseases (2009) (27)
Portal hypertension with bleeding vaginal varices. (1967) (26)
Medical safety and side effects of methadone in tolerant individuals. (1991) (26)
Individual differences in gene expression of vasopressin, D2 receptor, POMC and orexin: Vulnerability to relapse to heroin-seeking in rats (2015) (26)
Cocaine Affects Progesterone Plasma Levels in Female Rats (2000) (26)
Elevation of guinea pig brain preprodynorphin mRNA expression and hypothalamic-pituitary-adrenal axis activity by “binge” pattern cocaine administration (2001) (26)
Self administration of oxycodone by adolescent and adult mice affects striatal neurotransmitter receptor gene expression (2014) (26)
Adolescent and Young Adult Heroin Patients (2006) (26)
Comparison of the discriminative and neuroendocrine effects of centrally penetrating κ-opioid agonists in rhesus monkeys (2002) (25)
Chronic liver disease in abusers of alcohol and parenteral drugs: a report of 204 consecutive biopsy-proven cases. (1986) (25)
Personality as a risk factor for illicit opioid use and a protective factor for illicit opioid dependence. (2014) (25)
Effects of systemically administered dynorphin A(1-17) in rhesus monkeys. (1999) (25)
Availability of reliable serum methadone determination for management of symptomatic patients. (1995) (24)
Fructose:Glucose Ratios—A Study of Sugar Self-Administration and Associated Neural and Physiological Responses in the Rat (2015) (24)
Tolerance and dependence: implications for the pharmacological treatment of addiction. (1987) (24)
Sex differences after chronic stress in the expression of opioid-, stress- and neuroplasticity-related genes in the rat hippocampus (2018) (24)
Proopiomelanocortin (POMC) expression and conditioned place aversion during protracted withdrawal from chronic intermittent escalating-dose heroin in POMC-EGFP promoter transgenic mice (2013) (24)
Strain and cocaine-induced differential opioid gene expression may predispose Lewis but not Fischer rats to escalate cocaine self-administration (2016) (24)
Effects of selective D1- or D2-like dopamine receptor antagonists with acute "binge" pattern cocaine on corticotropin-releasing hormone and proopiomelanocortin mRNA levels in the hypothalamus. (2004) (24)
Dopaminergic pathway polymorphisms and heroin addiction: further support for association of CSNK1E variants. (2014) (23)
Voluntary alcohol drinking enhances proopiomelanocortin gene expression in nucleus accumbens shell and hypothalamus of Sardinian alcohol-preferring rats. (2013) (23)
Effects of memantine alone and with acute 'binge' cocaine on hypothalamic-pituitary-adrenal activity in the rat. (1998) (23)
Reliability of sequential naloxone challenge tests. (1995) (23)
Immune function in heroin addicts and former heroin addicts in treatment: pre- and post-AIDS epidemic. (1990) (23)
Dynorphin A (1-8) analog, E-2078, crosses the blood-brain barrier in rhesus monkeys. (1997) (23)
Alcoholism and polydrug use: the need for the "basics". (1984) (22)
Biliary secretion of methadone and methadone metabolites in man. (1980) (22)
Setting Priorities for Genomic Research (2004) (22)
Effects of opiates, opioid antagonists and cocaine on the endogenous opioid system: clinical and laboratory studies. (1992) (22)
Chronic Oxycodone Self-administration Altered Reward-related Genes in the Ventral and Dorsal Striatum of C57BL/6J Mice: An RNA-seq Analysis (2018) (22)
In vitro biotransformation of dynorphin A (1-17) is similar in human and rhesus monkey blood as studied by matrix-assisted laser desorption/ionization mass spectrometry. (1996) (22)
Adolescent oxycodone self administration alters subsequent oxycodone-induced conditioned place preference and anti-nociceptive effect in C57BL/6J mice in adulthood (2016) (22)
Peripheral selectivity and apparent efficacy of dynorphins: comparison to non-peptidic κ-opioid agonists in rhesus monkeys (2004) (22)
Suppression of Hypothalamic–Pituitary–Adrenal Axis by Acute Heroin Challenge in Rats During Acute and Chronic Withdrawal from Chronic Heroin Administration (2013) (21)
Nerve growth factor beta polypeptide (NGFB) genetic variability: association with the methadone dose required for effective maintenance treatment (2011) (21)
Human spinal fluid methadone levels. (1978) (21)
Methadone-maintained patients. (1974) (21)
Behavioral Effects and Central Nervous System Levels of the Broadly Available κ-Agonist Hallucinogen Salvinorin A Are Affected by P-Glycoprotein Modulation In Vivo (2012) (21)
Impact of Pharmacological Manipulation of the κ-Opioid Receptor System on Self-grooming and Anhedonic-like Behaviors in Male Mice (2019) (21)
Synergistic blockade of alcohol escalation drinking in mice by a combination of novel kappa opioid receptor agonist Mesyl Salvinorin B and naltrexone (2017) (20)
Clock reset for alcoholism (2005) (20)
Evidence for association of two variants of the nociceptin/orphanin FQ receptor gene OPRL1 with vulnerability to develop opiate addiction in Caucasians (2010) (20)
Both dynorphin A(1-17) and [Des-Tyr1]dynorphin A(2-17) inhibit adenylyl cyclase activity in rat caudate putamen. (1996) (20)
Relationships between Endocrine Functions and Substance Abuse Syndromes (2002) (20)
Dynorphin A (1-8) analog, E-2078, is stable in human and rhesus monkey blood. (1997) (20)
Use of positron emission tomography to measure the effects of nalmefene on D1 and D2 dopamine receptors in rat brain (1997) (19)
Correlation Between High Methadone Doses and Methadone Serum Levels in Methadone Maintenance Treatment (MMT) Patients (2007) (19)
Thrombocytosis in the Offspring of Female Mice Receiving dl-Methadone 1 (1980) (19)
Apparent efficacy of κ-opioid receptor ligands on serum prolactin levels in rhesus monkeys (1999) (19)
Idiopathic cholestasis of pregnancy. The response to challenge with the synthetic estrogen, ethinyl estradiol. (1967) (19)
Quantitative medial temporal lobe brain morphology and hypothalamic-pituitary-adrenal axis function in cocaine dependence: a preliminary report. (2001) (19)
Addictions and stress: clues for cocaine pharmacotherapies. (2013) (19)
Sex Differences in the Rat Hippocampal Opioid System After Oxycodone Conditioned Place Preference (2018) (18)
Combination of Clinically Utilized Kappa-Opioid Receptor Agonist Nalfurafine With Low-Dose Naltrexone Reduces Excessive Alcohol Drinking in Male and Female Mice. (2019) (18)
Effects of Hepatitis C and HIV on Cognition in Women: Data From the Women's Interagency HIV Study (2012) (18)
Structure and expression of the guinea pig preproenkephalin gene: site-specific cleavage in the 3' untranslated region yields truncated mRNA transcripts in specific brain regions (1995) (18)
The Effects of Herkinorin, the First μ-Selective Ligand from a Salvinorin A-Derived Scaffold, in a Neuroendocrine Biomarker Assay in Nonhuman Primates (2008) (18)
EFFECTS OF CHRONIC EXOGENOUS OPIOID ADMINISTRATION ON LEVELS OF ONE ENDOGENOUS OPIOID (β-ENDORPHIN) IN MAN (1981) (18)
Association of polymorphisms of the mu opioid receptor gene with the severity of HIV infection and response to HIV treatment. (2012) (17)
Opioids, dopamine, stress, and the addictions (2007) (17)
Dopamine gene variants in opioid addiction: comparison of dependent patients, nondependent users and healthy controls. (2018) (17)
Synaptic Plasticity and Signal Transduction Gene Polymorphisms and Vulnerability to Drug Addictions in Populations of European or African Ancestry (2015) (17)
Expression of Ephrin Receptors and Ligands in Postmortem Brains of HIV-Infected Subjects With and Without Cognitive Impairment (2013) (17)
Acute withdrawal from chronic escalating-dose binge cocaine administration alters kappa opioid receptor stimulation of [ 35 S] guanosine 5′-O-[gamma-thio]triphosphate acid binding in the rat ventral tegmental area (2010) (17)
Variants of opioid system genes are associated with non-dependent opioid use and heroin dependence. (2016) (17)
Gradualism, identity, reinforcements, and change (2005) (17)
Plasma and urine levels of methadone. Comparison following four medication forms used in chronic maintenance treatment. (1973) (17)
Measuring the incentive value of escalating doses of heroin in heroin-dependent Fischer rats during acute spontaneous withdrawal (2011) (17)
kappa-Opioid receptor agonist-induced prolactin release in primates is blocked by dopamine D(2)-like receptor agonists. (2001) (16)
Estimating ancestral proportions in a multi-ethnic US sample: implications for studies of admixed populations (2012) (16)
Antibody to LAV, the putative agent of AIDS, in parenteral drug abusers and methadone-maintained patients: therapeutic, historical, and ethical aspects. (1986) (16)
GR89,696: a potent kappa-opioid agonist with subtype selectivity in rhesus monkeys. (2001) (16)
Markers for hepatitis A, B and C in methadone maintained patients: an unexpectedly high co-infection with silent hepatitis B. (2008) (16)
Opiate-ethanol interactions: implications for the biological basis and treatment of combined addictive diseases. (1988) (16)
Acute and chronic cocaine differentially alter the subcellular distribution of AMPA GluR1 subunits in region-specific neurons within the mouse ventral tegmental area (2010) (15)
The μ-opioid receptor nonsynonymous variant 118A>G is associated with prolonged abstinence from heroin without agonist treatment. (2017) (15)
Acute subjective effects of dynorphin A(1-13) infusion in normal healthy subjects. (1999) (15)
Guinea pig preprodynorphin mRNA: primary structure and regional quantitation in the brain. (1996) (14)
Clinical Update of Opioid Agonist and Partial Agonist Medications for the Maintenance Treatment of Opioid Addiction (1997) (14)
Cocaine Impairs Maternal Nest Building in Pregnant Rats (1997) (14)
Prospective Study of QTc Changes Among Former Opiate Addicts Since Admission to Methadone Maintenance Treatment: Benzodiazepine Risk (2013) (14)
Novelty-induced locomotor activity in Long–Evans rats pre- and post-chronic `binge'-pattern cocaine treatment (1997) (14)
V1b Receptor Antagonist SSR149415 and Naltrexone Synergistically Decrease Excessive Alcohol Drinking in Male and Female Mice (2018) (14)
Sex Differences in Neuroplasticity- and Stress-Related Gene Expression and Protein Levels in the Rat Hippocampus Following Oxycodone Conditioned Place Preference (2019) (14)
Involvement of Activated Brain Stress Responsive Systems in Excessive and “Relapse” Alcohol Drinking in Rodent Models: Implications for Therapeutics (2018) (14)
Goals and rationale for pharmacotherapeutic approach in treating cocaine dependence: insights from basic and clinical research. (1997) (14)
Susceptibility loci for heroin and cocaine addiction in the serotonergic and adrenergic pathways in populations of different ancestry. (2015) (14)
Specificity of antibody tests for human immunodeficiency virus in alcohol and parenteral drug abusers with chronic liver disease. (1988) (14)
Repeated Administration of Opra Kappa (LY2456302), a Novel, Short-Acting, Selective KOP-r Antagonist, in Persons with and without Cocaine Dependence (2018) (14)
The Stimulation of Albumin Synthesis by Methadone (1976) (14)
Liver function tests in non-parenteral cocaine users. (1990) (13)
Chronic ‘binge’ pattern cocaine alters the neuroendocrine profile of pregnant rats (2000) (13)
Quantification of multiple mRNA levels in rat brain regions using real time optical PCR. (2003) (13)
Modulation of cocaine-related behaviors by low doses of the potent KOR agonist nalfurafine in male C57BL6 mice (2020) (13)
Involvement of tissue plasminogen activator in stress responsivity during acute cocaine withdrawal in mice (2010) (13)
Glutamatergic and GABAergic susceptibility loci for heroin and cocaine addiction in subjects of African and European ancestry (2016) (13)
Hypothalamic CRH mRNA levels are differentially modulated by repeated 'binge' cocaine with or without D(1) dopamine receptor blockade. (2001) (13)
Hepatitis C virus serology in parenteral drug users with chronic liver disease. (1997) (12)
Reliability of salivary cortisol assessments in cocaine dependent individuals (2006) (12)
Regional mRNA expression of the endogenous opioid and dopaminergic systems in brains of C57BL/6J and 129P3/J mice: Strain and heroin effects (2011) (12)
MOLECULAR AND CELLULAR NEUROBIOLOGY AND PATHOPHYSIOLOGY OF OPIATE ADDICTION (2001) (12)
Tolerance and sensitization to chronic escalating dose heroin following extended withdrawal in Fischer rats: possible role of mu-opioid receptors (2012) (12)
Persistent increases in rat hypothalamic POMC gene expression following chronic withdrawal from chronic “binge” pattern escalating-dose, but not steady-dose, cocaine (2015) (12)
Clinical problems associated with interactions between methadone pharmacotherapy and medications used in the treatment of HIV-1-positive and AIDS patients (1995) (12)
Long-Term Pharmacotherapy for Opiate (Primarily Heroin) Addiction: Opioid Antagonists and Partial Agonists (1996) (12)
Cholestasis of Pregnancy and during Ethinyl Estradiol Administration in the Human and Rat (1969) (12)
Physiologic implications of methadone treatment. (1973) (12)
Sex differences in the effect of bupropion and naltrexone combination on alcohol drinking in mice (2019) (11)
Chronic stress differentially alters mRNA expression of opioid peptides and receptors in the dorsal hippocampus of female and male rats (2021) (11)
The Personality Assessment Inventory Drug Problems Scale: A Validity Analysis (2002) (11)
Non-medical Cannabis Self-Exposure as a Dimensional Predictor of Opioid Dependence Diagnosis: A Propensity Score Matched Analysis (2018) (11)
Effects of Kappa opioid receptor blockade by LY2444296 HCl, a selective short-acting antagonist, during chronic extended access cocaine self-administration and re-exposure in rat (2020) (11)
Effects of mesyl salvinorin B alone and in combination with naltrexone on alcohol deprivation effect in male and female mice (2018) (11)
African-specific variability in the acetylcholine muscarinic receptor M4: association with cocaine and heroin addiction. (2016) (11)
Opioid Disposition and Effects During Chronic Exposure in the Perinatal Period in Man (1982) (11)
Differential glutamate AMPA-receptor plasticity in subpopulations of VTA neurons in the presence or absence of residual cocaine: Implications for the development of addiction (2011) (11)
Primary structure of guinea pig preprodynorphin and preproenkephalin mRNAs: multiple transcription initiation sites for preprodynorphin (2004) (11)
A non-coding CRHR2 SNP rs255105, a cis-eQTL for a downstream lincRNA AC005154.6, is associated with heroin addiction (2018) (11)
The effects of naltrexone maintenance on the response to yohimbine in healthy volunteers (1999) (10)
Comparison of methods for quantitation of radioactivity in protected hybrids in RNase protection assays. (1998) (10)
Identification of substance use and dependence among patients with viral hepatitis. (2010) (10)
Apparent efficacy of kappa-opioid receptor ligands on serum prolactin levels in rhesus monkeys. (1999) (10)
Genetic variations in genes of the stress response pathway are associated with prolonged abstinence from heroin. (2018) (10)
Long-term followup studies of the medical status of adolescent former heroin addicts in chronic methadone maintenance treatment: liver disease and immune status. (1986) (10)
On Blending Practice and Research (2006) (10)
Re-evaluation of the KMSK scales, rapid dimensional measures of self-exposure to specific drugs: Gender-specific features. (2018) (10)
Simplified quantitation of urinary benzoylecgonine in cocaine addiction research and for related pharmacotherapeutic trials. (1996) (10)
Chronic immobilization stress primes the hippocampal opioid system for oxycodone‐associated learning in female but not male rats (2019) (10)
Dynorphin A(1–13) Analgesia in Opioid-Treated Patients with Chronic Pain (1999) (10)
Effects of withdrawal from chronic escalating-dose binge cocaine on conditioned place preference to cocaine and striatal preproenkephalin mRNA in C57BL/6J mice (2012) (10)
Medications for substance use disorders (SUD): emerging approaches (2017) (10)
Treatment-like steady-state methadone in rats interferes with incubation of cocaine sensitization and associated alterations in gene expression (2012) (10)
Nuclear transcriptional changes in hypothalamus of Pomc enhancer knockout mice after excessive alcohol drinking (2019) (9)
VMAT2 gene (SLC18A2) variants associated with a greater risk for developing opioid dependence. (2019) (9)
Endogenous opioid system in addiction and addiction-related behaviors (2017) (9)
Increased OPRM1 DNA Methylation in Lymphocytes of Methadone (2009) (9)
Genetic diversity and linkage disequilibrium in the chemokine receptor CCR2-CCR5 region among individuals and populations. (2013) (9)
Stable isotopes: essential tools in biological and medical research (1978) (9)
Methadone disposition following oral versus parenteral dose administration in rats during chronic treatment. (1981) (9)
Immunological approaches to clinical issues in drug abuse. (1988) (9)
High-throughput molecular haplotype analysis (allelic assignment) of single-nucleotide polymorphisms by fluorescent polymerase chain reaction. (2004) (9)
Gender-specific association of functional prodynorphin 68 bp repeats with cannabis exposure in an African American cohort (2018) (9)
Are trait impulsivity and exposure to cannabis or alcohol associated with the age of trajectory of cocaine use? A gender-specific dimensional analysis in humans with cocaine dependence diagnosis. (2020) (9)
A New Heroin Epidemic (1975) (9)
Limited effects of β-endorphin compared to loperamide or fentanyl in a neuroendocrine biomarker assay in non-human primates (2008) (9)
Effects of alcohol abuse on progression of liver disease in methadone-maintained patients. (1979) (8)
Basal total opioid peptide release in the striatum of rats with cholestasis from bile duct resection: a study by the use of in vivo microdialysis. (1997) (8)
“Binge” cocaine differentially alters preproenkephalin mRNA levels in guinea pig brain (2003) (8)
Neurocognitive and neuroinflammatory correlates of PDYN and OPRK1 mRNA expression in the anterior cingulate in postmortem brain of HIV-infected subjects (2014) (8)
Sex and chronic stress differentially alter phosphorylated mu and delta opioid receptor levels in the rat hippocampus following oxycodone conditioned place preference (2019) (8)
Opioid receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database (2019) (8)
Drug interactions with methadone in humans. (1986) (8)
Ablation of Pituitary Pro‐Opiomelanocortin (POMC) Cells Produces Alterations in Hypothalamic POMC mRNA Levels and Midbrain µ Opioid Receptor Binding in a Conditional Transgenic Mouse Model (2001) (8)
A rave at ecstasy (1997) (8)
Cocaine place conditioning increases pro-opiomelanocortin gene expression in rat hypothalamus (2012) (8)
Treating chronic hepatitis C in recovering opiate addicts: yes, we can. (2009) (8)
Neurobiology of Opiates and Opioids (2015) (8)
A window of opportunity: maximizing the effectiveness of new HCV regimens in the United States with the expansion of the Affordable Care Act. (2015) (8)
Neuroendocrine (HPA) and gastrointestinal effects of opiate antagonists: possible therapeutic application. (1990) (8)
Acute binge pattern cocaine administration induces region-specific effects in D1-r- and D2-r-expressing cells in eGFP transgenic mice (2013) (8)
Factors modifying the pharmacological effectiveness of methadone.: (471722004-001) (1983) (8)
Clinically utilized kappa-opioid receptor agonist nalfurafine combined with low-dose naltrexone prevents alcohol relapse-like drinking in male and female mice (2019) (8)
Pharmacology of Opiates (1998) (7)
Salvinorin A, a kappa-opioid receptor agonist hallucinogen: pharmacology and potential template for novel pharmacotherapeutic agents in neuropsychiatric disorders (2015) (7)
A 3’ UTR SNP rs885863, a cis-eQTL for the circadian gene VIPR2 and lincRNA 689, is associated with opioid addiction (2019) (7)
Kappa Opioid Receptor Antagonists as Potential Therapeutics for Mood and Substance Use Disorders. (2020) (7)
The Use of Levo-Alpha-Acetylmethadol (LAAM) in Methadone Patients Who Have Not Achieved Heroin Abstinence (2002) (7)
Immunological function in active heroin addicts and methadone-maintained former addicts: observations and possible mechanisms. (1990) (7)
Association of Variants of Arginine Vasopressin and Arginine Vasopressin Receptor 1A With Severe Acetaminophen Liver Injury (2017) (7)
Biological correlates of methadone maintenance pharmacotherapy. (1994) (7)
Methadone, monoamine oxidase, and depression: opioid distribution and acute effects on enzyme activity. (1983) (7)
Escalation of drug use in persons dually diagnosed with opioid and cocaine dependence: Gender comparison and dimensional predictors. (2019) (7)
Methadone Maintenance Treatment Experience in Macao – Prospective Follow-up for Initial 4.5 Years (2013) (7)
Estrogen induced cholestasis due to endogenous and exogenous hormones. (1970) (7)
Naltrexone and nalmefene attenuate cocaine place preference in male mice (2018) (7)
Polymorphisms of the Kappa Opioid Receptor and Prodynorphin Genes: HIV Risk and HIV Natural History (2013) (6)
Methadone : history , pharmacology , neurobiology , and use (2004) (6)
Effects of morphine on prolactin receptors in the rat brain (1994) (6)
Methadone Maintenance Treatment for Harm Reduction Approach to Heroin Addiction (1991) (6)
Oprm1 A112G, a single nucleotide polymorphism, alters expression of stress-responsive genes in multiple brain regions in male and female mice (2018) (6)
Neuroendocrine effects of naltrexone versus nalmefene in humans (2020) (6)
Association of variants of prodynorphin promoter 68-bp repeats in caucasians with opioid dependence diagnosis: Effect on age trajectory of heroin use (2019) (6)
Steady-state methadone effect on generalized arousal in male and female mice. (2008) (6)
Kappa opioid receptor mRNA levels in the rat brain: Effects of dopamine antagonists and cocaine (1994) (6)
Changes in methadone pharmacokinetics during pregnancy (1982) (6)
Genetic Variant in the CRH-binding Protein Gene (CRHBP) is Associated With Cessation of Cocaine Use in Methadone Maintenance Patients With Opioid Addiction. (2019) (6)
Nalfurafine modulates the reinforcing effects of oxycodone in male and female adolescent C57BL/6J mice (2020) (6)
Introduction to Addictive Disorders: Implications for Pharmacotherapies (2007) (6)
Clinical and demographic features of patients admitted to a new chemical dependency program in New York City. (1987) (5)
Design, synthesis, and preliminary evaluation of a potential synthetic opioid rescue agent (2021) (5)
Effects of route of administration on methadone disposition in the rat. (1981) (5)
Regional mRNA expression of GABAergic receptor subunits in brains of C57BL/6J and 129P3/J mice: Strain and heroin effects (2013) (5)
Population-specific genetic background for the OPRM1 variant rs1799971 (118A>G): implications for genomic medicine and functional analysis (2020) (5)
LC-MS/MS quantification of salvinorin A from biological fluids. (2013) (5)
Antidepressant Treatment Patterns in a Novel Methadone Maintenance Clinic Targeting Young Adults (2006) (5)
Mu opioid receptor mRNA levels following chronic naltrexone administration (1994) (5)
Depression during methadone withdrawal: No role for β-phenylethylamine (1984) (5)
mTORC1 pathway is involved in the kappa opioid receptor activation-induced increase in excessive alcohol drinking in mice (2020) (5)
Overview and historical perspective of four papers presented on research related to the endogenous opioid system. (2010) (5)
Profile of a short-acting κ-antagonist, LY2795050, on self-grooming behaviors, forced swim test and locomotor activity: sex comparison in mice (2021) (5)
Functions of Arginine Vasopressin and Its Receptors: Importance of Human Molecular Genetics Studies in Bidirectional Translational Research (2011) (5)
Genetic Vulnerability to Opioid Addiction. (2020) (5)
The Genetics of Impulsivity (2011) (4)
Can a rapid measure of self‐exposure to drugs of abuse provide dimensional information on depression comorbidity? (2017) (4)
Impact of bidirectional translational research on treatment of addiction (2005) (4)
Methadone and immune function. (1992) (4)
"Skinny needle" cholangiography--results of a pilot study of a voluntary prospective method for gathering risk data on new procedures. (1980) (4)
Relapse-like behavior in a mouse model of the OPRM1 (mu-opioid receptor) A118G polymorphism: Examination with intravenous oxycodone self-administration (2020) (4)
Discriminative Stimulus Properties of Opioid Ligands: Progress and Future Directions. (2016) (4)
Effect of ethnicity, gender and drug use history on achieving high rates of affirmative informed consent for genetics research: impact of sharing with a national repository (2011) (4)
Relative expression of mRNA for the somatostatin receptors in the caudate putamen of C57BL/6J and 129P3/J mice: Strain and heroin effects (2010) (4)
Variants of opioid genes and response to treatment of opioid use disorder with buprenorphine-naloxone versus extended-release naltrexone in Caucasians (2020) (4)
The effect of methadone in vitro on natural killer (NK) activity. (1989) (4)
Preclinical Studies on Nalfurafine (TRK-820), a Clinically Used KOR Agonist. (2021) (4)
OPRD1 SNPs associated with opioid addiction are cis-eQTLs for the phosphatase and actin regulator 4 gene, PHACTR4, a mediator of cytoskeletal dynamics (2021) (4)
Sex and chronic stress alter delta opioid receptor distribution within rat hippocampal CA1 pyramidal cells following behavioral challenges (2020) (4)
Murine model of OPRM1 A118G alters oxycodone self-administration and locomotor activation, but not conditioned place preference (2019) (3)
Diseases of the gallbladder and biliary passages. (1975) (3)
Title : Carbon Dioxide-Induced Anesthesia Results in a Rapid Increase in Plasma Levels of Vasopressin Short Title : CO 2-induced Increase in Plasma Vasopressin (2009) (3)
Modulation of NK activity: role of neuroendocrine status. (1990) (3)
Chronic naltrexone effect on cortisol. (1986) (3)
Keynote Address: Neurobiological Correlates of the Addictions: Findings From Basic and Treatment Research (1998) (3)
Oxycodone injections not paired with conditioned place preference have little effect on the hippocampal opioid system in female and male rats (2020) (3)
Extended access oxycodone self-administration and neurotransmitter receptor gene expression in the dorsal striatum of adult C57BL/6 J mice (2013) (3)
Regional Quantitation of Preprodynorphin mRNA in Guinea Pig Gastrointestinal Tract (1998) (3)
Nalmefene, a mu opioid receptor antagonist/kappa opioid receptor partial agonist, potentiates cocaine motivation but not intake with extended access self-administration in adult male mice (2021) (3)
Distribution of opioid peptides in brain and GI tract: age- and species-specific differences. (1990) (3)
Self-administration of oxycodone by adolescent and adult mice differentially affects hypothalamic mitochondrial metabolism gene expression (2015) (3)
NIDA's commitment to tackling drug abuse (2004) (3)
Pharmacological Treatment of Addiction: Normalization of Physiology and AIDS Risk Reduction (1995) (3)
Association of Serotonin Transporter (SERT) Polymorphisms with Opioid Dependence and Dimensional Aspects of Cocaine Use in a Caucasian Cohort of Opioid Users (2021) (3)
Kappa Opioids: Problems and Opportunities in Analgesia (2013) (3)
Analyses of polymorphisms of intron 2 of OPRK1 (kappa-opioid receptor gene) in association with opioid and cocaine dependence diagnoses in an African-American population (2021) (3)
Suppression of Hypothalamic–Pituitary–Adrenal Axis by Acute Heroin Challenge in Rats During Acute and Chronic Withdrawal from Chronic Heroin Administration (2013) (2)
Depression during methadone withdrawal: no role for beta-phenylethylamine. (1984) (2)
Further evidence for association of GAL, GALR1 and NPY1R variants with opioid dependence. (2020) (2)
METHADONE AND IMMUNE FUNCTION. REPLY (1992) (2)
Pharmacotherapy of opioid dependence: Rationale and update (1994) (2)
Opioid receptors in GtoPdb v.2021.3 (2021) (2)
Blockade of alcohol excessive and “relapse” drinking in male mice by pharmacological cryptochrome (CRY) activation (2021) (2)
MU OPIOID RECEPTOR mRNA LEVELS FOLLOWING CHRONIC ADMINISTRATION OF OPIOID LIGANDS (1995) (2)
Drugs of abuse and immunosuppression. (1994) (2)
Resurgence of abuse of amphetamine-type stimulants (1998) (2)
Clues to Understanding the Oxidation of Estradiol in Humans (2009) (2)
ESTROGEN TREATMENT ALTERS NARCOTIC DISPOSITION IN THE RAT (1980) (2)
Cocaine: Usage, Misuse, and Addiction Processes. An Overview (2016) (2)
Hepatitis C treatment, subcutaneous naltrexone implants, and methadone maintenance treatment (2007) (2)
Acute Withdrawal from Chronic Escalating-Dose Binge Cocaine Administration Alters Kappa Opioid Receptor Stimulation of [35S]GTPγS Binding in the Rat Ventral Tegmental Area (2013) (2)
Adolescent oxycodone self administration alters subsequent antinociceptive effect of oxycodone in C57BL/6J mice in adulthood (2015) (2)
100 – Endocrine Systems Interacting with Brain and Behavior: Laboratory and Clinical Studies of Heroin and Other Short-Acting Opiates versus Methadone and Other Long-Acting Opioids (2009) (2)
Human immunodeficiency virus and viral hepatitis seroepidemiology in New York City intravenous drug abusers (IVDAs). (1989) (2)
Detecting Polymorphisms in G Protein-Coupled Receptor Genes (2011) (2)
Genetics of Opioid Addiction (2013) (2)
Tolerance and sensitization to chronic escalating dose heroin following extended withdrawal in Fischer rats: possible role of mu-opioid receptors (2012) (1)
Involvement of KOP-r in cocaine withdrawal-induced conditioned place aversion in rats (2014) (1)
Quantification of preprodynorphin (DYN) mRNA in guinea pig gut using a highly sensitive solution hybridization assay (1995) (1)
22 Pharmacology of Opiates USA BORG (1)
CRF versus AVP in human stress responsivity: Initial studies (2015) (1)
Kappa and delta opioid receptor densities following chronic repeated cocaine administration (1994) (1)
Kappa Opioid Receptors and Mu Opioid Receptors as Combined Targets for Medication Development for Alcoholism (2019) (1)
Effects of drugs of abuse and treatment agents in women. (1992) (1)
Recent alcoholism treatment research: ethical issues of implementation into clinical practice (1997) (1)
Basal neuroendocrine status and cocaine craving measurements in active cocaine-dependent volunteers at admission and after 8 weeks of abstinence (2015) (1)
Distribution and polysome association of full-length and 3' truncated preproenkephalin mRNA in the guinea-pig brain. (1997) (1)
Self-Administrationof Oxycodone by Adolescent and Adult Mice Differentially Affects Hypothalamic Mitochondrial Metabolism Gene Expression (2014) (1)
Narcotic blockade. 1966. (1991) (1)
Rapid F-18 labeling of peptides using aniline catalyzed oximation with [18F]FDG (2011) (1)
Bidirectional influence of heroin and cocaine escalation in persons with dual opioid and cocaine dependence diagnoses. (2020) (1)
The stimulation of albumin sythesis by methadone. (1976) (1)
Acute Delta 9‐tetrahydrocannabinol administration differentially alters the hippocampal opioid system in adult female and male rats (2021) (1)
The BiolAD-DB System (2012) (1)
Stress-related genes and heroin addiction: A role for functional fkbp5 variants (2015) (1)
Corrigendum to “Opioid receptor and peptide gene polymorphisms: potential implications for addictions” [Eur. J. Pharmacol. 410 (2001) 249–268] (2001) (1)
Gene variants of the opioid system – Relationship to heroin self-exposure, addiction, and treatment (2015) (1)
Polymorphisms in Stress-Related Genes Are Associated with Reduced Cocaine Abuse and Longer Retention in Methadone Maintenance Treatment for Opioid Use Disorder (2020) (1)
Heroin Addiction & Related Clinical Problems - June 2007 (2007) (1)
Alcohol drinking and related behaviors in hypothalamic-specific Pomc-deficient mice (2015) (1)
Setting priorities for genomic research [2] (multiple letters) (2004) (1)
Attenuation of the hypothalamic-pituitary-adrenal response to chronic “binge” pattern cocaine administration corresponds to decreased CRH mRNA in rat hypothalamus (1994) (1)
Alterations of expression of inflammation/immune-related genes in the dorsal and ventral striatum of adult C57BL/6J mice following chronic oxycodone self-administration: a RNA sequencing study (2017) (0)
HEROIN ADDICTION AND RELATED (2005) (0)
United States and Europe : perspectives for the future treatment for opiate addiction provided by diverse medical resources using methadone, LAAM and buprenorphine (1998) (0)
Association of the OPRM1 Variant rs1799971 (A118G) with Non-Specific Liability to Substance Dependence in a Collaborative de novo Meta-Analysis of European-Ancestry Cohorts (2015) (0)
Hepatic cirrhosis inyoungadults: association with adolescent onsetofalcohol andparenteral heroin abuse (1985) (0)
Oprm1 A112G, a single nucleotide polymorphism, alters expression of stress-responsive genes in multiple brain regions in male and female mice (2018) (0)
Recurrent Cholestatic Jaundice with Demonstrated Estrogen (1967) (0)
Symposium for 20th anniversary celebration of NIDA: Update on opioid receptor cloning: Implications for research on addiction (1995) (0)
Blockade of alcohol escalation and “relapse” drinking by pharmacological FAAH inhibition in male and female C57BL/6J mice (2017) (0)
Method of treating patients suffering from chronic pain or chronic cough us patent 4769372. september 6 1988 (1988) (0)
NALOXONE IN CHRONIC CONSTIPATION (1983) (0)
Sex and chronic stress alter the distribution of glutamate receptors within rat hippocampal CA3 pyramidal cells following oxycodone conditioned place preference (2022) (0)
NDT_A_286536 659..670 (2021) (0)
Short Title: CO2-induced Increase in Plasma Vasopressin (2009) (0)
Oxytocin Co Administered With Low-Dose Naltrexone Decreased Excessive and “Relapse” Alcohol Drinking In Mice (2022) (0)
Predisposing genetic differences contribute to vulnerability to escalate cocaine intake in rats (2015) (0)
Single nucleotide polymorphisms of the human preproenkephalin gene in association with opiate addiction (2004) (0)
Bruce S. McEwen, Ph.D. (2020) (0)
Expression of Ephrin Receptors and Ligands in Postmortem Brains of HIV-Infected Subjects With and Without Cognitive Impairment (2013) (0)
[Effect of tetracycline on the daryotype of the fetus]. (1967) (0)
Dose escalation and dose preference in extended-access heroin self-administration in Lewis and Fischer rats (2011) (0)
alcohol and parenteral heroin abuse . association with adolescent onset of Hepatic cirrhosis in young adults : (2006) (0)
The Hypothalamic–Pituitary–Adrenal Axis and Related Brain Stress-Response Systems and Heroin (2016) (0)
Characterization of Pyrrolidinyl-hexahydro-pyranopiperazines as a Novel Kappa Opioid Receptor Agonist Scaffold. (2022) (0)
The genetics of the opioid system and specific drug addictions (2012) (0)
Effects of the short-acting KOP-r antagonist [D-TRP]CJ-15,208 on cocaine self-administration, locomotor activity, and food intake in male C57/BL6 mice (2014) (0)
DRUG ABUSE AND THE GENOME (1997) (0)
Markku Linnoila, MD, PhD, 1947-1998 (1998) (0)
119. Addiction, personality traits, stress, and AIDS: Possible role of specific gene variants and epigenetic changes (2008) (0)
Reversed phase thin-layer chromatography for the separation of beta-endorphin, beta-lipotropin and enkephalins. (1983) (0)
Gene expession in addictive disorders (2002) (0)
55. Increased DNA methylation in the promoter region of the μ-opioid receptor gene (ORPM1) in lymphocytes of Caucasian methadone maintained former heroin addicts (2008) (0)
Different sensitivity for oxycodone-induced conditioned place preference and sensitization of locomotor activity in adolescent and adult mice (2014) (0)
Heroin Add 7(2).indb (2005) (0)
AWindowofOpportunity:MaximizingtheEffectiveness ofNewHCVRegimensintheUnitedStatesWiththe ExpansionoftheAffordableCareAct (2015) (0)
Association of the prodynorphin gene promoter repeat polymorphism with basal prolactin level in normal human male volunteers (2014) (0)
Repeated, daily cocaine administration produces changes in basal and opioid-regulated adenylyl cyclase activity in rat caudate-putamen and nucleus accubens (1993) (0)
Addictive diseases and depression comorbidity: Age trajectory and gender comparison (2017) (0)
Partial kappa opioid receptor agonist effects in vivo in mice: Biased versus unbiased (2017) (0)
Design, synthesis, and preliminary evaluation of a potential synthetic opioid rescue agent (2021) (0)
Author response for "Chronic stress differentially alters mRNA expression of opioid peptides and receptors in the dorsal hippocampus of female and male rats" (2020) (0)
Effects of Kappa opioid receptor blockade by LY2444296 HCl, a selective short-acting antagonist, during chronic extended access cocaine self-administration and re-exposure in rat (2020) (0)
A (CA)n Repeat Polymorphism in Enkephalin Gene: Association with Opiate Addiction (2004) (0)
Chapter 35 – Addictions (2015) (0)
Back Cover: Cover Image, Volume 73, Issue 5 (2019) (0)
Liver function tests in non-parenteral cocaine users. (1990) (0)
Modulation of cocaine-related behaviors by low doses of the potent KOR agonist nalfurafine in male C57BL6 mice (2020) (0)
Neuroendocrine function and the relationship to addictions. (1996) (0)
Measuring the incentive value of escalating doses of heroin in heroin-dependent Fischer rats during acute spontaneous withdrawal (2011) (0)
“Effects of the novel relatively short-acting kappa opioid receptor antagonist LY2444296 in behaviors observed after chronic extended-access cocaine self-administration in rats” (2017) (0)
The Pharmacology of Opioids (0)
Oxycodone-induced conditioned place preference and locomotor activity in adult female C57BL/6J mice (2015) (0)
REGIONAL DISTRIBUTION OF FULL-LENGTH AND 3′ TRUNCATED PREPROENKEPHALIN mRNA IN THE GUINEA PIG BRAIN (1995) (0)
Age of onset of heaviest use of cannabis or alcohol in persons with severe opioid or cocaine use disorders. (2021) (0)
Gene variants of the dopaminergic system are associated with non-dependent heroin use and heroin dependence (2017) (0)
The Widely Available Hallucinogenic Plant Salvia divinorum and Its Main Component, Salvinorin A (2016) (0)
Use of opium antagonist for the manufacture of medicines to correct gastrointestinal disorders. (1983) (0)
460. Opioid abnormalities in alcoholism: naltrexone induced responses (2000) (0)
RNA-seq analysis: Differential transcriptome in the dorsal and ventral striatum in male C57BL/6J mice after chronic oxycodone self-administration (2017) (0)
Reversed phase thin‐layer chromatography for the separation of β‐endorphin, β‐lipotropin and enkephalins (2009) (0)
Opioids, single nucleotide polymorphisms, and addictions (1999) (0)
Gender differences in HCV viral load among methadone-maintained patients (2002) (0)
Editorial: A new "heroin epidemic"? (1975) (0)
The Laboratory of the Biology of Addictive Diseases: Four Women in Neuroscience (2019) (0)
Novel and Previously Reported Single-Nucleotide Polymorphisms in the Human 5-HT1B Receptor Gene (2018) (0)
Stereoselective disposition of R-(-)- and S-(+)-methadone in man (1978) (0)
Liver, Pancreas and Biliary Tract Identification of substance use and dependence among patients with viral hepatitis (2010) (0)
Principles of Psychiatric Genetics: Human molecular genetics of opioid addiction (2012) (0)
Exposure to HIV-1 Tat protein potentiates the rewarding effects of morphine and reinstates extinguished conditioned place preference (2015) (0)
S.10.01 Behavioural and neurochemical correlates of relapse vulnerability to cocaine and oxycodone seeking in laboratory rats (2011) (0)
4.21 – Endocrinological Effects of Drugs of Abuse (2017) (0)
Dual addiction. Pharmacological issues in the treatment of concomitant alcoholism and drug abuse. (1984) (0)
Adolescent C57BL/6J mice self-administer more oxycodone than adult mice in an extended-access paradigm (4 h) (2015) (0)
Addiction and addictive disorders (2016) (0)
Neurocognitive and neuroinflammatory correlates of PDYN and OPRK1 mRNA expression in the anterior cingulate in postmortem brain of HIV-infected subjects (2014) (0)
Estimating ancestral proportions in a multi-ethnic US sample: implications for studies of admixed populations (2012) (0)
Handling and vehicle injections impact corticosterone but not adrenocorticotropic hormone levels in Sprague-Dawley but not Lewis rats (2014) (0)
Stress and Feedback of Adrenal Steroids (1998) (0)

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