Masahiko Negishi

Q: What Schools Are Affiliated With Masahiko Negishi

Masahiko Negishi is affiliated with the following schools: University of California, Berkeley, University of Tokyo, Institute of Science Tokyo, Kyoto University

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Masahiko Negishi

Computer Science

#5576

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#5889

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Computational Linguistics

#812

World Rank

#825

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Machine Learning

#1534

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#1556

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Artificial Intelligence

#1766

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#1798

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Computer Science

Masahiko Negishi's Degrees

PhD Computer Science University of Tokyo
Masters Computer Science University of Tokyo
Bachelors Computer Science University of Tokyo

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Masahiko Negishi's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

The Nuclear Orphan Receptor CAR-Retinoid X Receptor Heterodimer Activates the Phenobarbital-Responsive Enhancer Module of the CYP2B Gene (1998) (742)
The Repressed Nuclear Receptor CAR Responds to Phenobarbital in Activating the Human CYP2B6 Gene* (1999) (679)
Phenobarbital-Responsive Nuclear Translocation of the Receptor CAR in Induction of the CYP2B Gene (1999) (559)
Regulation of cytochrome P450 (CYP) genes by nuclear receptors. (2000) (498)
Diverse roles of the nuclear orphan receptor CAR in regulating hepatic genes in response to phenobarbital. (2002) (473)
CAR and PXR: The xenobiotic-sensing receptors (2007) (423)
The phenobarbital response enhancer module in the human bilirubin UDP‐glucuronosyltransferase UGT1A1 gene and regulation by the nuclear receptor CAR (2001) (378)
Phenobarbital response elements of cytochrome P450 genes and nuclear receptors. (2001) (376)
Alteration of mouse cytochrome P450coh substrate specificity by mutation of a single amino-acid residue (1989) (370)
The Orphan Nuclear Receptor Constitutive Active/Androstane Receptor Is Essential for Liver Tumor Promotion by Phenobarbital in Mice (2004) (343)
Nuclear Receptors CAR and PXR Cross Talk with FOXO1 To Regulate Genes That Encode Drug-Metabolizing and Gluconeogenic Enzymes (2004) (323)
Relative Activation of Human Pregnane X Receptor versus Constitutive Androstane Receptor Defines Distinct Classes of CYP2B6 and CYP3A4 Inducers (2007) (301)
Complementary Roles of Farnesoid X Receptor, Pregnane X Receptor, and Constitutive Androstane Receptor in Protection against Bile Acid Toxicity* (2003) (295)
Structure and function of sulfotransferases. (2001) (290)
Developmental exposure to diethylstilbestrol elicits demethylation of estrogen-responsive lactoferrin gene in mouse uterus. (1997) (280)
Genetic mechanisms controlling the induction of polysubstrate monooxygenase (P-450) activities. (1981) (262)
Crystal structure of estrogen sulphotransferase (1997) (240)
A Novel Distal Enhancer Module Regulated by Pregnane X Receptor/Constitutive Androstane Receptor Is Essential for the Maximal Induction of CYP2B6 Gene Expression* (2003) (224)
Induction of Human CYP2C9 by Rifampicin, Hyperforin, and Phenobarbital Is Mediated by the Pregnane X Receptor (2004) (223)
Differential Regulation of Hepatic CYP2B6 and CYP3A4 Genes by Constitutive Androstane Receptor but Not Pregnane X Receptor (2006) (199)
Identification of a defect in the UGT1A1 gene promoter and its association with hyperbilirubinemia. (2002) (199)
Cytoplasmic Localization of Pregnane X Receptor and Ligand-dependent Nuclear Translocation in Mouse Liver* (2004) (191)
Human CYP2C8 Is Transcriptionally Regulated by the Nuclear Receptors Constitutive Androstane Receptor, Pregnane X Receptor, Glucocorticoid Receptor, and Hepatic Nuclear Factor 4α (2005) (190)
Identification of constitutive androstane receptor and glucocorticoid receptor binding sites in the CYP2C19 promoter. (2003) (186)
Cytoplasmic accumulation of the nuclear receptor CAR by a tetratricopeptide repeat protein in HepG2 cells. (2003) (186)
Regulation of CYP2B6 in primary human hepatocytes by prototypical inducers. (2004) (185)
Drug-activated nuclear receptors CAR and PXR (2003) (179)
Nuclear Pregnane X Receptor Cross-talk with FoxA2 to Mediate Drug-induced Regulation of Lipid Metabolism in Fasting Mouse Liver* (2007) (174)
Phenobarbital Indirectly Activates the Constitutive Active Androstane Receptor (CAR) by Inhibition of Epidermal Growth Factor Receptor Signaling (2013) (172)
Identification of the nuclear receptor CAR:HSP90 complex in mouse liver and recruitment of protein phosphatase 2A in response to phenobarbital (2003) (167)
Activation by diverse xenochemicals of the 51-base pair phenobarbital-responsive enhancer module in the CYP2B10 gene. (1998) (166)
The Peptide Near the C Terminus Regulates Receptor CAR Nuclear Translocation Induced by Xenochemicals in Mouse Liver (2001) (161)
Heparan/Chondroitin Sulfate Biosynthesis (2000) (160)
Regulation of human CYP2C9 by the constitutive androstane receptor: discovery of a new distal binding site. (2002) (159)
Estrogen activation of the nuclear orphan receptor CAR (constitutive active receptor) in induction of the mouse Cyp2b10 gene. (2000) (154)
The Ah locus: Correlation of intranuclear appearance of inducer-receptor complex with induction of cytochrome P1-450 mRNA (1982) (149)
Conserved structural motifs in the sulfotransferase family. (1998) (149)
Characterization of a Phenobarbital-responsive Enhancer Module in Mouse P450 Cyp2b10 Gene* (1997) (148)
CAR, driving into the future. (2004) (146)
Human Constitutive Androstane Receptor Mediates Induction of CYP2B6 Gene Expression by Phenytoin* (2004) (146)
The roles of nuclear receptors CAR and PXR in hepatic energy metabolism. (2008) (142)
Estrogen Receptor α Mediates 17α-Ethynylestradiol Causing Hepatotoxicity* (2006) (137)
Synthesis and insertion of cytochrome P-450 into endoplasmic reticulum membranes. (1980) (133)
Transcriptional Regulation of Human UGT1A1 Gene Expression: Activated Glucocorticoid Receptor Enhances constitutive Androstane Receptor/Pregnane X Receptor-Mediated UDP-Glucuronosyltransferase 1A1 Regulation with Glucocorticoid Receptor-Interacting Protein 1 (2005) (132)
Structural gene products of the Ah locus. Genetic and immunochemical evidence for two forms of mouse liver cytochrome P-450 induced by 3-methylcholanthrene. (1979) (130)
Human nuclear pregnane X receptor cross-talk with CREB to repress cAMP activation of the glucose-6-phosphatase gene. (2007) (125)
Crystal Structure of the Sulfotransferase Domain of Human Heparan Sulfate N-Deacetylase/ N-Sulfotransferase 1* (1999) (123)
Multiple forms of cytochrome P-450 and the importance of molecular biology and evolution. (1982) (122)
Dephosphorylation of Threonine 38 Is Required for Nuclear Translocation and Activation of Human Xenobiotic Receptor CAR (NR1I3)* (2009) (122)
Phenobarbital-elicited activation of nuclear receptor CAR in induction of cytochrome P450 genes. (2000) (120)
Transcriptional regulation of cytochrome p450 2B genes by nuclear receptors. (2003) (118)
The Nuclear Receptors Constitutive Androstane Receptor and Pregnane X Receptor Cross-Talk with Hepatic Nuclear Factor 4α to Synergistically Activate the Human CYP2C9 Promoter (2005) (116)
Characterization of Phenobarbital-inducible Mouse Cyp2b10 Gene Transcription in Primary Hepatocytes (*) (1996) (112)
The environmental pollutant 1,1-dichloro-2,2-bis (p-chlorophenyl)ethylene induces rat hepatic cytochrome P450 2B and 3A expression through the constitutive androstane receptor and pregnane X receptor. (2003) (110)
Crystal Structure of an α1,4-N-Acetylhexosaminyltransferase (EXTL2), a Member of the Exostosin Gene Family Involved in Heparan Sulfate Biosynthesis* (2003) (106)
The dimerization motif of cytosolic sulfotransferases (2001) (105)
Protein serine/threonine phosphatase inhibitors suppress phenobarbital-induced Cyp2b10 gene transcription in mouse primary hepatocytes. (1998) (104)
Crystal structure of SULT2A3, human hydroxysteroid sulfotransferase (2000) (104)
The Peripheral Benzodiazepine Receptor Ligand 1-(2-Chlorophenyl-methylpropyl)-3-isoquinoline-carboxamide Is a Novel Antagonist of Human Constitutive Androstane Receptor (2008) (103)
Crystal structure of human catecholamine sulfotransferase. (1999) (100)
Mutations affecting the regulation of transcription of the cytochrome P1-450 gene in the mouse Hepa-1 cell line. (1985) (100)
Mouse steroid 15 alpha-hydroxylase gene family: identification of type II P-450(15)alpha as coumarin 7-hydroxylase. (1989) (99)
The Sulfuryl Transfer Mechanism (1998) (96)
The Ah locus, a multigene family necessary for survival in a chemically adverse environment: comparison with the immune system. (1982) (96)
A DNA methylation site in the male-specific P450 (Cyp 2d-9) promoter and binding of the heteromeric transcription factor GABP (1995) (94)
Role of constitutive androstane receptor in the in vivo induction of Mrp3 and CYP2B1/2 by phenobarbital. (2002) (93)
Structural Analysis of the Sulfotransferase (3-O-Sulfotransferase Isoform 3) Involved in the Biosynthesis of an Entry Receptor for Herpes Simplex Virus 1* (2004) (92)
Purification and characterization of heterologously expressed mouse CYP2A5 and CYP2G1: role in metabolic activation of acetaminophen and 2,6-dichlorobenzonitrile in mouse olfactory mucosal microsomes. (1998) (92)
Nuclear receptor CAR as a regulatory factor for the sexually dimorphic induction of CYB2B1 gene by phenobarbital in rat livers. (2001) (91)
Glucocorticoid receptor enhancement of pregnane X receptor-mediated CYP2B6 regulation in primary human hepatocytes. (2003) (89)
Estrogen receptor alpha mediates 17alpha-ethynylestradiol causing hepatotoxicity. (2006) (88)
Nuclear receptors CAR and PXR in the regulation of hepatic metabolism (2006) (88)
Molecular characterization of a testis-specific estrogen sulfotransferase and aberrant liver expression in obese and diabetogenic C57BL/KsJ-db/db mice. (1995) (87)
The structure, function, and regulation of cytochrome P450 2A enzymes. (1997) (86)
New insights on the xenobiotic-sensing nuclear receptors in liver diseases--CAR and PXR--. (2008) (82)
Pretranslational regulation of sex-dependent testosterone hydroxylases by growth hormone in mouse liver. (1986) (82)
Extracellular Signal-Regulated Kinase Is an Endogenous Signal Retaining the Nuclear Constitutive Active/Androstane Receptor (CAR) in the Cytoplasm of Mouse Primary Hepatocytes (2007) (78)
IDENTIFICATION OF HMG-CoA REDUCTASE INHIBITORS AS ACTIVATORS FOR HUMAN, MOUSE AND RAT CONSTITUTIVE ANDROSTANE RECEPTOR (2005) (76)
Serine 202 Regulates the Nuclear Translocation of Constitutive Active/Androstane Receptor (2006) (74)
Regulatory DNA elements of phenobarbital‐responsive cytochrome P450 CYP2B genes (1998) (74)
The role of the nuclear receptor CAR as a coordinate regulator of hepatic gene expression in defense against chemical toxicity. (2003) (74)
The role of the nuclear receptor constitutive androstane receptor in the pathogenesis of non-alcoholic steatohepatitis (2006) (74)
Reciprocal regulation of sex-dependent expression of testosterone 15 alpha-hydroxylase (P-450(15 alpha)) in liver and kidney of male mice by androgen. Evidence for a single gene. (1988) (74)
Mouse decay-accelerating factor: selective and tissue-specific induction by estrogen of the gene encoding the glycosylphosphatidylinositol-anchored form. (1996) (73)
Crystal Structure of the Human Estrogen Sulfotransferase-PAPS Complex (2002) (71)
Phenobarbital Confers its Diverse Effects by Activating the Orphan Nuclear Receptor Car (2006) (70)
Crystal Structure and Mutational Analysis of Heparan Sulfate 3-O-Sulfotransferase Isoform 1* (2004) (70)
2-O-Phosphorylation of Xylose and 6-O-Sulfation of Galactose in the Protein Linkage Region of Glycosaminoglycans Influence the Glucuronyltransferase-I Activity Involved in the Linkage Region Synthesis* (2008) (69)
Sexually dimorphic DNA demethylation in the promoter of the Slp (sex-limited protein) gene in mouse liver. (1995) (69)
Cellular localization and regulation of expression of testicular estrogen sulfotransferase. (1997) (69)
Structural flexibility and functional versatility of mammalian P450 enzymes (1996) (68)
Structural gene product of the [Ah] complex. Evidence for transcriptional control of cytochrome P1-450 induction by use of a cloned DNA sequence. (1981) (68)
Structural analysis by X-ray crystallography and calorimetry of a haemagglutinin component (HA1) of the progenitor toxin from Clostridium botulinum. (2003) (68)
The structure and characterization of type I P-450(15) alpha gene as major steroid 15 alpha-hydroxylase and its comparison with type II P-450(15) alpha gene. (1989) (67)
Developmental action of estrogen receptor-alpha feminizes the growth hormone-Stat5b pathway and expression of Cyp2a4 and Cyp2d9 genes in mouse liver. (1999) (67)
Phenobarbital induction of drug/steroid-metabolizing enzymes and nuclear receptor CAR. (2003) (66)
SLC13A5 Is a Novel Transcriptional Target of the Pregnane X Receptor and Sensitizes Drug-Induced Steatosis in Human Liver (2015) (65)
Crystallographic analysis of a hydroxylated polychlorinated biphenyl (OH-PCB) bound to the catalytic estrogen binding site of human estrogen sulfotransferase. (2003) (64)
Crystal Structure of β1,3-Glucuronyltransferase I in Complex with Active Donor Substrate UDP-GlcUA* (2002) (63)
Mouse liver testosterone 15 alpha-hydroxylase (cytochrome P-450(15) alpha). Purification, regioselectivity, stereospecificity, and sex-dependent expression. (1984) (63)
Identification of Ginkgo biloba as a Novel Activator of Pregnane X Receptor (2008) (62)
Regulation of gene expression by CAR: an update (2015) (59)
A nuclear factor (NF2d9) that binds to the male-specific P450 (Cyp 2d-9) gene in mouse liver (1995) (59)
Substrate Gating Confers Steroid Specificity to Estrogen Sulfotransferase* (1999) (57)
Crystal structure‐based studies of cytosolic sulfotransferase (2001) (55)
Rip locus: regulation of female-specific isozyme (I-P-450(16 alpha) of testosterone 16 alpha-hydroxylase in mouse liver, chromosome localization, and cloning of P-450 cDNA. (1988) (55)
Mouse pulmonary cytochrome P-450 naphthalene hydroxylase: cDNA cloning, sequence, and expression in Saccharomyces cerevisiae. (1991) (55)
Discovery of estrogen sulfotransferase inhibitors from a purine library screen. (2001) (54)
A role of Lys614 in the sulfotransferase activity of human heparan sulfate N‐deacetylase/N‐sulfotransferase (1998) (54)
Promoter CpG methylation of Hox‐a10 and Hox‐a11 in mouse uterus not altered upon neonatal diethylstilbestrol exposure * (2001) (54)
Active ERK1/2 Protein Interacts with the Phosphorylated Nuclear Constitutive Active/Androstane Receptor (CAR; NR1I3), Repressing Dephosphorylation and Sequestering CAR in the Cytoplasm* (2011) (54)
Role of CYP2A5 and 2G1 in acetaminophen metabolism and toxicity in the olfactory mucosa of the Cyp1a2(-/-) mouse. (1998) (53)
Crystal Structure of Human Cholesterol Sulfotransferase (SULT2B1b) in the Presence of Pregnenolone and 3′-Phosphoadenosine 5′-Phosphate (2003) (53)
Isolation and characterization of a cloned DNA sequence associated with the murine Ah locus and a 3-methylcholanthrene-induced form of cytochrome P-450. (1981) (53)
Flame retardant BDE-47 effectively activates nuclear receptor CAR in human primary hepatocytes. (2014) (53)
Nuclear Receptor CAR Represses TNFα-Induced Cell Death by Interacting with the Anti-Apoptotic GADD45B (2010) (52)
Statin-activated nuclear receptor PXR promotes SGK2 dephosphorylation by scaffolding PP2C to induce hepatic gluconeogenesis (2015) (52)
The constitutive active/androstane receptor regulates phenytoin induction of Cyp2c29. (2004) (52)
Structural gene products of the Ah complex. Increases in large mRNA from mouse liver associated with cytochrome P1-450 induction by 3-methylcholanthrene. (1981) (51)
Pregnane X Receptor PXR Activates the GADD45β Gene, Eliciting the p38 MAPK Signal and Cell Migration* (2010) (51)
Novel CAR-mediated Mechanism for Synergistic Activation of Two Distinct Elements within the Human Cytochrome P450 2B6 Gene in HepG2 Cells* (2005) (50)
Glucosaminylglycan biosynthesis: what we can learn from the X-ray crystal structures of glycosyltransferases GlcAT1 and EXTL2. (2003) (50)
Gene family of male-specific testosterone 16 alpha-hydroxylase (C-P-450(16) alpha) in mouse liver: cDNA sequences, neonatal imprinting, and reversible regulation by androgen. (1987) (49)
Posttranscriptional regulation of coumarin 7-hydroxylase induction by xenobiotics in mouse liver: mRNA stabilization by pyrazole. (1991) (49)
Interaction of aflatoxin B1 with cytochrome P450 2A5 and its mutants: correlation with metabolic activation and toxicity. (1997) (49)
Regulation of the human UGT1A1 gene by nuclear receptors constitutive active/androstane receptor, pregnane X receptor, and glucocorticoid receptor. (2005) (49)
Engineering mouse P450coh to a novel corticosterone 15 alpha-hydroxylase and modeling steroid-binding orientation in the substrate pocket. (1993) (48)
Mechanism of induction of cytochrome p450 enzymes by the proestrogenic endocrine disruptor pesticide-methoxychlor: interactions of methoxychlor metabolites with the constitutive androstane receptor system. (2001) (48)
Mouse liver testosterone 16 alpha-hydroxylase (cytochrome P-450(16) alpha). Purification, regioselectivity, stereospecificity, and immunochemical characterization. (1984) (48)
The Human Sulfotransferase SULT1A1 Gene Is Regulated in a Synergistic Manner by Sp1 and GA Binding Protein (2004) (48)
Phenytoin Induction of the Cyp2c37 Gene Is Mediated by the Constitutive Androstane Receptor (2006) (47)
Separation of acetanilide and its hydroxylated metabolites and quantitative determination of "acetanilide 4-hydroxylase activity" by high-pressure liquid chromatography. (1979) (46)
Structural function of residue-209 in coumarin 7-hydroxylase (P450coh). Enzyme-kinetic studies and site-directed mutagenesis. (1991) (46)
PPP1R16A, The Membrane Subunit of Protein Phosphatase 1β, Signals Nuclear Translocation of the Nuclear Receptor Constitutive Active/Androstane Receptor (2008) (46)
Site-directed mutagenesis of mouse steroid 7 alpha-hydroxylase (cytochrome P-450(7) alpha): role of residue-209 in determining steroid-cytochrome P-450 interaction. (1993) (46)
Pregnane X receptor regulates drug metabolism and transport in the vasculature and protects from oxidative stress (2011) (46)
Are estrogens carcinogenic during development of the testes? (1998) (45)
Orphan nuclear receptor constitutive active/androstane receptor-mediated alterations in DNA methylation during phenobarbital promotion of liver tumorigenesis. (2007) (45)
Biosynthesis of cytochrome P-450 on membrane-bound ribosomes and its subsequent incorporation into rough and smooth microsomes in rat hepatocytes (1979) (45)
Alteration of high and low spin equilibrium by a single mutation of amino acid 209 in mouse cytochromes P450. (1991) (44)
Purification and partial characterization of hepatic microsomal cytochrome P-450s from phenobarbital- and 3-methylcholanthrene-treated rats. (1979) (44)
Effect of various cations on the acidity of p-sulfonatocalixarenes (1998) (44)
Liganded pregnane X receptor represses the human sulfotransferase SULT1E1 promoter through disrupting its chromatin structure (2011) (42)
Distribution and induction of cytochrome P-450 in rat liver nuclear envelope (1981) (41)
Differential UGT1A1 Induction by Chrysin in Primary Human Hepatocytes and HepG2 Cells (2005) (41)
Mouse glycine N-methyltransferase is sexually dimorphic and regulated by growth hormone. (1997) (41)
The Nuclear Receptor Constitutively Active/Androstane Receptor Regulates Type 1 Deiodinase and Thyroid Hormone Activity in the Regenerating Mouse Liver (2007) (40)
Gene family of male-specific testosterone 16 alpha-hydroxylase (C-P-450(16 alpha)) in mice. Organization, differential regulation, and chromosome localization. (1989) (39)
Cytochrome P4502A5 expression and inducibility by phenobarbital is modulated by cAMP in mouse primary hepatocytes. (1994) (39)
Characterization of cytochrome P2-450 (20-S) mRNA. Association with the P1-450 genomic gene and differential response to the inducers 3-methylcholanthrene and isosafrole. (1983) (38)
Primary structures of multiple forms of cytochrome P-450 isozyme 2 derived from rabbit pulmonary and hepatic cDNAs. (1988) (37)
Inter-α-trypsin Inhibitor Promotes Bronchial Epithelial Repair after Injury through Vitronectin Binding* (2009) (37)
Coordinated Regulation of Nuclear Receptor CAR by CCRP/DNAJC7, HSP70 and the Ubiquitin-Proteasome System (2014) (36)
Garlic Extract Diallyl Sulfide (DAS) Activates Nuclear Receptor CAR to Induce the Sult1e1 Gene in Mouse Liver (2011) (36)
Activation volume and energetic properties of the binding of CO to hemoproteins. (1994) (36)
Mouse steroid sulfotransferases: substrate specificity and preliminary X-ray crystallographic analysis. (1998) (36)
Structural gene products of the murine Ah complex. Differences in ontogenesis and glucosamine incorporation between liver microsomal cytochromes P1-450 and P-448 induced by polycyclic aromatic compounds. (2005) (36)
Crystal Structure of the Human Estrogen Sulfotransferase-PAPS Complex EVIDENCE FOR CATALYTIC ROLE OF Ser IN THE SULFURYL TRANSFER REACTION* (2002) (35)
Quantitation of hepatic cytochrome P1-450 mRNA with the use of a cloned DNA probe. Effects of various P-450 inducers in C57BL/6N and DBA/2N mice. (1982) (35)
Cloning and nucleotide sequence of a novel, male-predominant carboxylesterase in mouse liver. (1993) (34)
Sulfotransferase genes: Regulation by nuclear receptors in response to xeno/endo-biotics (2013) (34)
Nuclear Xenobiotic Receptor Pregnane X Receptor Locks Corepressor Silencing Mediator for Retinoid and Thyroid Hormone Receptors (SMRT) onto the CYP24A1 Promoter to Attenuate Vitamin D3 Activation (2009) (34)
Molecular characterization of the murine Coh locus: an amino acid difference at position 117 confers high and low coumarin 7-hydroxylase activity in P450coh. (1992) (33)
Structure and Function of HNK-1 Sulfotransferase (1999) (33)
Isosafrole-induced cytochrome P2-450 in DBA/2N mouse liver. Characterization and genetic control of induction. (1984) (33)
Structural flexibility and functional versatility of cytochrome P450 and rapid evolution. (1996) (33)
Sexual dimorphism of testosterone 15 alpha-hydroxylase mRNA levels in mouse liver. cDNA cloning and regulation. (1985) (33)
Molecular engineering of microsomal P450 2a-4 to a stable, water-soluble enzyme. (1995) (32)
cDNA cloning and sequence of CYP2C29 encoding P-450 MUT-2, a microsomal aldehyde oxygenase. (1994) (32)
Nuclear Receptor CAR Requires Early Growth Response 1 to Activate the Human Cytochrome P450 2B6 Gene* (2008) (32)
Regulation of Cyp2a5 transcription in mouse primary hepatocytes: roles of hepatocyte nuclear factor 4 and nuclear factor I. (2004) (31)
Dietary flavonoids activate the constitutive androstane receptor (CAR). (2010) (31)
Transcriptional regulation by HNF-4 of the steroid 15α-hydroxylase P450 (Cyp2a-4) gene in mouse liver (1997) (31)
Phenobarbital Meets Phosphorylation of Nuclear Receptors (2017) (31)
Induction of microsomal dimethylnitrosamine demethylase by pyrazole. (1982) (30)
Phosphorylated Nuclear Receptor CAR Forms a Homodimer To Repress Its Constitutive Activity for Ligand Activation (2017) (30)
Species-specific responses of constitutively active receptor (CAR)-CYP2B coupling: lack of CYP2B inducer-responsive nuclear translocation of CAR in marine teleost, scup (Stenotomus chrysops). (2002) (30)
Roles of residues 129 and 209 in the alteration by cytochrome b5 of hydroxylase activities in mouse 2A P450S. (1992) (30)
PXR cross-talks with internal and external signals in physiological and pathophysiological responses (2013) (29)
Site of biosynthesis of cytochrome P450 in hepatocytes of phenobarbital treated rats. (1976) (28)
Serum- and Glucocorticoid-Regulated Kinase 2 Determines Drug-Activated Pregnane X Receptor to Induce Gluconeogenesis in Human Liver Cells (2014) (28)
Molecular cloning and characterization of a novel nuclear protein kinase in mice. (1998) (27)
Nuclear receptor CAR (NR1I3) is essential for DDC-induced liver injury and oval cell proliferation in mouse liver (2011) (26)
The Antiapoptotic Factor Growth Arrest and DNA-Damage-Inducible 45 β Regulates the Nuclear Receptor Constitutive Active/Androstane Receptor-Mediated Transcription (2008) (26)
Structures and characterization of sex-specific mouse cytochrome P-450 genes as members within a large family. Duplication boundary and evolution. (1991) (26)
Pregnane X Receptor Represses HNF4α Gene to Induce Insulin-Like Growth Factor–Binding Protein IGFBP1 that Alters Morphology of and Migrates HepG2 Cells (2015) (25)
Activation of aflatoxin B1 by mouse CYP2A enzymes and cytotoxicity in recombinant yeast cells. (1994) (25)
Characterization of a cDNA for rat P-450g, a highly polymorphic, male-specific cytochrome in the P-450IIC subfamily. (1989) (25)
Residue threonine 350 confers steroid hormone responsiveness to the mouse nuclear orphan receptor CAR. (2002) (24)
The Chondroitin Polymerase K4CP and the Molecular Mechanism of Selective Bindings of Donor Substrates to Two Active Sites* (2008) (24)
Early growth response 1 loops the CYP2B6 promoter for synergistic activation by the distal and proximal nuclear receptors CAR and HNF4α (2009) (23)
Sexual dimorphisms in zonal gene expression in mouse liver. (2013) (23)
Overexpression of a cytochrome P-450 of the 2a family (Cyp2a-5) in chemically induced hepatomas from female mice. (1994) (23)
The Roles of Co-Chaperone CCRP/DNAJC7 in Cyp2b10 Gene Activation and Steatosis Development in Mouse Livers (2014) (23)
Heparan sulphate N-sulphotransferase activity: reaction mechanism and substrate recognition. (2003) (22)
Localization of the nuclear receptor CAR at the cell membrane of mouse liver (2005) (22)
Similarities between mouse and rat-liver microsomal cytochromes P-450 induced by 3-methylcholanthrene. Evidence from catalytic, immunologic, and recombinant DNA studies. (1982) (22)
Comparison between cobalt and pyrazole in the increased expression of coumarin 7-hydroxylase in mouse liver. (1991) (22)
Retinoic acids repress constitutive active receptor-mediated induction by 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene of the CYP2B10 gene in mouse primary hepatocytes. (2002) (21)
Serine 216 Phosphorylation of Estrogen Receptor α in Neutrophils: Migration and Infiltration into the Mouse Uterus (2013) (21)
A trans-acting locus regulates transcriptional repression of the female-specific steroid 15 alpha-hydroxylase gene in male mice. (1993) (21)
Phosphorylation of Farnesoid X Receptor at Serine 154 Links Ligand Activation With Degradation. (2016) (21)
Female-predominant expression of testosterone 16α-hydroxylase (“I”-P-45016α) and its repression in strain 129/J (1986) (20)
Thr176 regulates the activity of the mouse nuclear receptor CAR and is conserved in the NR1I subfamily members PXR and VDR. (2005) (20)
Localization of nascent NADPH-cytochrome c reductase in rat liver microsomes. (1975) (20)
Expression of CAR in SW480 and HepG2 cells during G1 is associated with cell proliferation. (2008) (20)
Nuclear receptor phosphorylation in xenobiotic signal transduction (2020) (20)
Cytochrome P1-450 structural gene in mouse, rat, and rabbit: differences in DNA methylation and developmental expression of mRNA. (1982) (20)
Structure of the mouse cytochrome P1-450 genomic gene. (1983) (19)
p38 Mitogen–Activated Protein Kinase Regulates Nuclear Receptor CAR that Activates the CYP2B6 Gene (2013) (19)
Inherent versatility of P-450 oxygenase. Conferring dehydroepiandrosterone hydroxylase activity to P-450 2a-4 by a single amino acid mutation at position 117. (1994) (19)
Direct expression of fluorescent protein-tagged nuclear receptor CAR in mouse liver. (2002) (19)
Chapter 13:Receptor-Mediated Regulation of Cytochromes P450 (2008) (19)
Role of nuclear receptor CAR in carbon tetrachloride-induced hepatotoxicity. (2005) (18)
Human SULT1A genes: cloning and activity assays of the SULT1A promoters. (2005) (18)
Presence of apo-cytochrome beta 5 in microsomes from rat liver. (1970) (17)
Interaction of the phosphorylated DNA-binding domain in nuclear receptor CAR with its ligand-binding domain regulates CAR activation (2017) (17)
Altering the regiospecificity of androstenedione hydroxylase activity in P450s 2a-4/5 by a mutation of the residue at position 481. (1995) (17)
INDUCTION OF GENES FOR METABOLISM AND TRANSPORT BY TRANS-STILBENE OXIDE IN LIVERS OF SPRAGUE-DAWLEY AND WISTAR-KYOTO RATS (2006) (17)
Searching for the minimum energy path in the sulfuryl transfer reaction catalyzed by human estrogen sulfotransferase: Role of enzyme dynamics (2006) (17)
Nuclear receptor CAR-regulated expression of the FAM84A gene during the development of mouse liver tumors. (2011) (17)
Nuclear xenobiotic receptor PXR-null mouse exhibits hypophosphatemia and represses the Na/Pi-cotransporter SLC34A2 (2010) (16)
Coordinated polypeptide synthesis and insertion of protoheme in cytochrome P-450 during development of endoplasmic reticulum membranes. (1978) (16)
Phenobarbital and Insulin Reciprocate Activation of the Nuclear Receptor Constitutive Androstane Receptor through the Insulin Receptor (2016) (16)
The roles of individual amino acids in altering substrate specificity of the P450 2a4/2a5 enzymes. (1996) (16)
Phosphorylation of serine 212 confers novel activity to human estrogen receptor α (2012) (15)
Glucose elicits serine/threonine kinase VRK1 to phosphorylate nuclear pregnane X receptor as a novel hepatic gluconeogenic signal. (2017) (15)
Functional characterization of two cytochrome P-450s within the mouse, male-specific steroid 16 alpha-hydroxylase gene family: expression in mammalian cells and chimeric proteins. (1989) (15)
Heparan sulfate biosynthesis: a theoretical study of the initial sulfation step by N-deacetylase/N-sulfotransferase. (2000) (15)
The Structural Basis for a Coordinated Reaction Catalyzed by a Bifunctional Glycosyltransferase in Chondroitin Biosynthesis* (2012) (15)
Multiple steroid-binding orientations: alteration of regiospecificity of dehydroepiandrosterone 2- and 7-hydroxylase activities of cytochrome P-450 2a-5 by mutation of residue 209. (1995) (14)
Post-transcriptional regulation of coumarin 7-hydroxylase (P450coh) induction by xenobiotics in mouse liver: mRNA stabilization by pyrazole (1991) (14)
The Nuclear Receptors Constitutive Active/Androstane Receptor and Pregnane X Receptor Activate the Cyp2c55 Gene in Mouse Liver (2010) (14)
A specific cis-acting element regulates in vitro transcription of sex-dependent mouse steroid 16 alpha-hydroxylase (C-P450(16 alpha)) gene. (1990) (14)
3'-Phosphoadenosine 5'-phosphosulfate binding site of flavonol 3-sulfotransferase studied by affinity chromatography and 31P NMR. (1999) (14)
p38 MAP Kinase Links CAR Activation and Inactivation in the Nucleus via Phosphorylation at Threonine 38 (2016) (14)
Explicit water near the catalytic I helix Thr in the predicted solution structure of CYP2A4. (2003) (13)
Alteration of the substrate specificity of mouse 2A P450s by the identity of residue-209: Steroid-binding site and orientation (1992) (13)
Reciprocal size-effect relationship of the key residues in determining regio- and stereospecificities of DHEA hydroxylase activity in P450 2a5. (1997) (13)
Photochemical Switching of Ferroelectric Liquid Crystals Using a Photoswitchable Chiral Dopant (1996) (13)
Role of CYP2B in Phenobarbital-Induced Hepatocyte Proliferation in Mice (2017) (12)
Two-step Mechanism That Determines the Donor Binding Specificity of Human UDP-N-acetylhexosaminyltransferase* (2005) (12)
Characterization of testosterone 16 alpha-hydroxylase (I-P-450(16) alpha) induced by phenobarbital in mice. (1985) (12)
Synthesis and Photochemical Switching of the Antiferroelectric Liquid Crystals Containing a Diazenediyl Group. (1996) (12)
Structural alteration of mouse P450coh by mutation of glycine-207 to proline: spin equilibrium, enzyme kinetics, and heat sensitivity. (1993) (11)
The early stage of labeling of microsomal membrane proteins in rat liver by radioactive amino acids. (1972) (11)
Cohesin protein SMC1 represses the nuclear receptor CAR-mediated synergistic activation of a human P450 gene by xenobiotics. (2006) (11)
Nuclear receptor CAR specifically activates the two-pore K+ channel Kcnk1 gene in male mouse livers, which attenuates phenobarbital-induced hepatic hyperplasia. (2013) (11)
Characterization and regulation of sex-specific mouse steroid hydroxylase genes. (1990) (11)
Nuclear receptor CAR-ERα signaling regulates the estrogen sulfotransferase gene in the liver (2020) (10)
Nuclear Receptor CAR Suppresses GADD45B-p38 MAPK Signaling to Promote Phenobarbital-induced Proliferation in Mouse Liver (2018) (10)
Role of a novel CAR-induced gene, TUBA8, in hepatocellular carcinoma cell lines. (2011) (10)
Lack of the steroid 15 alpha-hydroxylase gene (Cyp2a-4) in wild mouse strain Mus spretus: rapid evolution of the P450 gene superfamily. (1994) (10)
Estrogen receptor α phosphorylated at Ser216 confers inflammatory function to mouse microglia (2019) (9)
Two steroid 15α-hydroxylase genes and a homologous gene family in mice (1990) (9)
Expression of genes within mouse IIA and IID subfamilies: simultaneous measurement of homologous P450 mRNAs. (1991) (9)
Phenobarbital‐induced phosphorylation converts nuclear receptor RORα from a repressor to an activator of the estrogen sulfotransferase gene Sult1e1 in mouse livers (2018) (9)
Ligand induced dissociation of the AR homodimer precedes AR monomer translocation to the nucleus (2019) (9)
Expression and subcellular distribution of mouse cytochrome P1-450 mRNA as determined by molecular hybridization with cloned P1-450 DNA. (1982) (9)
Tissue-specific regulation of cytochrome P-450 dependent testosterone 15α-hydroxylase (1990) (9)
Experimental and modelling study of semi-continuous emulsion copolymerization of styrene and acrylonitrile (1985) (9)
Overexpression of the Rho‐guanine nucleotide exchange factor ECT2 inhibits nuclear translocation of nuclear receptor CAR in the mouse liver (2007) (8)
Genetic regulation of estrogen-dependent repression of female-specific testosterone 16 alpha-hydroxylase (I-P-450(16 alpha) in male mouse liver: murine Ripr locus. (1988) (8)
Sulfotransferase 4A1 Increases Its Expression in Mouse Neurons as They Mature (2018) (8)
Characterization of a cDNA for the unexpressed form of cytochrome P-450g from the (-g) rat and differentiation of its mRNA from that of the (+g) phenotype using specific oligoprobes. (1990) (8)
Estrogen Sulfotransferase (SULT1E1): Its Molecular Regulation, Polymorphisms, and Clinical Perspectives (2021) (8)
Modulation of specificity and activity in mammalian cytochrome P-450. (1991) (8)
Nuclear Receptor-Mediated Regulation of Cytochrome P450 Genes (2015) (8)
A quantum mechanical study of the transfer of biological sulfate (1999) (7)
Crystal Structure of the Human Estrogen Sulfotransferase-PAPS Complex EVIDENCE FOR CATALYTIC ROLE OF Ser (2002) (7)
A phosphorylation-deficient mutant of retinoid X receptor α at Thr 167 alters fasting response and energy metabolism in mice (2019) (7)
Genetic regulation of testosterone 15 alpha-hydroxylase (cytochrome P-450(15)alpha) in renal microsomes of female mice. (1986) (7)
Characterization of specific donor binding to alpha1,4-N-acetylhexosaminyltransferase EXTL2 using isothermal titration calorimetry. (2006) (7)
PXR Phosphorylated at Ser350 transduces a glucose signal to repress the estrogen sulfotransferase gene in human liver cells and fasting signal in mouse livers. (2020) (7)
Structure-function modeling of the interactions of N-alkyl-N-hydroxyanilines with rat hepatic aryl sulfotransferase IV. (2000) (7)
Co-Chaperone-Mediated Suppression of LPS-Induced Cardiac Toxicity Through NF&kgr;B Signaling (2017) (6)
Design, Synthesis and Physical Properties of New Liquid Crystal Materials Having a Fluoro-Substituted Tetrahydronaphthalene Structure for Active Matrix LCD (2004) (6)
CRYSTAL STRUCTURE OF BETA1,3-GLUCURONYLTRANSFERASE I IN COMPLEX WITH THE ACTIVE UDP-GLCUA DONOR (2002) (6)
Sex-dependent expression of mouse testosterone 16 alpha-hydroxylase (cytochrome P-450(16) alpha): cDNA cloning and pretranslational regulation. (1985) (6)
The nuclear receptor constitutive active/androstane receptor arrests DNA‐damaged human hepatocellular carcinoma Huh7 cells at the G2/M phase (2012) (5)
BASIC EQUATIONS FOR SIMULATION OF SEMI-CONTINUOUS OPERATION OF EMULSION POLYMERIZATION (1983) (5)
Phosphorylation of vaccinia-related kinase 1 at threonine 386 transduces glucose stress signal in human liver cells (2020) (5)
Genetic Differences in Enzymes which Metabolize Drugs, Chemical Carcinogens, and Other Environmental Pollutants (1983) (5)
Female-predominant expression of testosterone 16 alpha-hydroxylase ("I"-P-450(16)alpha) and its repression in strain 129/J. (1986) (5)
mitogen activated protein kinase regulates nuclear receptor CAR that activates the CYP 2 B 6 gene (2013) (5)
Environmental and genetic factors influencing drug metabolism and toxicity (1984) (4)
Structural gene products of the murine ah locus: immunochemical evidence for two forms of liver p-450 induced by 3-methylcholanthrene. Abstr. (1979) (4)
Glucocorticoid receptor dimerization in the cytoplasm might be essential for nuclear localization. (2021) (4)
Ser100-Phosphorylated RORα Orchestrates CAR and HNF4α to Form Active Chromatin Complex in Response to Phenobarbital to Regulate Induction of CYP2B6 (2020) (4)
Human constitutive androstane receptor represses liver cancer development and hepatoma cell proliferation by inhibiting erythropoietin signaling (2022) (4)
GR Utilizes a Co-Chaperone Cytoplasmic CAR Retention Protein to Form an N/C Interaction (2018) (3)
Sex-specific expression mechanism of hepatic estrogen inactivating enzyme and transporters in diabetic women. (2021) (3)
Androgen receptor phosphorylated at Ser815: the expression and function in the prostate and tumor-derived cells. (2021) (3)
RORα phosphorylation by casein kinase 1α as glucose signal to regulate estrogen sulfation in human liver cells (2020) (3)
Design, Synthesis and Physical Properties of New Liquid Crystal Materials for Active Matrix LCD (2) (2001) (3)
Nuclear pregnane X receptor cross-talks with CREB to repress cAMP activation of the glucose-6-phosphatase gene (2007) (3)
Crystal structure of human pregnenolone sulfotransferase (SULT2B1a) in the presence of PAP (2003) (3)
Cloning genes that encode inducible forms of P-450. (1984) (2)
STRUCTURAL GENE PRODUCTS OF THE MURINE Ah LOCUS. IMMUNOCHEMICAL CHARACTERIZATION OF TWO FORMS OF P-450 INDUCED BY POLYCYCLIC AROMATIC COMPOUNDS (1980) (2)
Cloning genes that encode drug-metabolizing enzymes: developmental pharmacology and teratology. (1983) (2)
Detection and Functional Analysis of Estrogen Receptor α Phosphorylated at Serine 216 in Mouse Neutrophils. (2016) (2)
Tissue-specific regulation of cytochrome P-450 dependent testosterone 15 alpha-hydroxylase. (1990) (2)
Mice blocking Ser347 phosphorylation of pregnane x receptor develop hepatic fasting-induced steatosis and hypertriglyceridemia. (2022) (2)
Two steroid 15 alpha-hydroxylase genes and a homologous gene family in mice. (1990) (2)
Transcriptional regulation of human UGT1A1 gene expression: Activated GR enhances CAR/PXR-mediated UGT1A1 regulation with GRIP1 (2004) (1)
CONSTITUTIVE ACTIVE RECEPTOR-MEDIATED INDUCTION BY 1 , 4-BIS [ 2-( 3 , 5-DICHLOROPYRIDYLOXY ) ] BENZENE OF THE CYP 2 B 10 GENE IN MOUSE PRIMARY HEPATOCYTES (2002) (1)
ACTIVE ERK 1 / 2 INTERACTS WITH PHOSPHORYLATED NUCLEAR RECEPTOR CAR ( NR 1 I 3 ) REPRESSING DEPHOSPHORYLATION AND SEQUESTERING IT IN THE CYTOPLASM (2011) (1)
Steroid hormone-dependent overexpression of cytochromes P450 2A in liver tumors of TGFα transgenic male mice (1997) (1)
SUN-LB134 Androgen Receptor Phosphorylated at Serine 815 in Mouse and Human Prostates (2020) (1)
Detection and Functional Analysis of Estrogen Receptor α Phosphorylated at Serine 216 in Mouse Neutrophils. (2022) (1)
Repression of phenobarbital-responsive enhancer module in the Cyp2b10 gene by estrogen receptor-related receptor ERR (2000) (1)
Design, Synthesis and Physical Properties of New Liquid Crystal Materials for Active Matrix LCD (1) (2001) (1)
Isolation and characterization of the mouse P1-450 chromosomal gene. (1982) (1)
Substrate specificities of cytochrome P-450, C-P-450(16)alpha and P-450(15)alpha, and contribution to steroid hydroxylase activities in mouse liver microsomes. (1988) (1)
Immunoprecipitation Analyses of Estrogen Receptor α Phosphorylated at Serine 216 in the Mouse Liver. (2022) (1)
The Nuclear Receptors CAR and PXR Activate the Cyp 2 c 55 Gene in Mouse Liver (2010) (1)
Differential UGT 1 A 1 Induction by Chrysin in Primary Human Hepatocytes and HepG 2 Cells (2005) (1)
Crystal Structure-Based Analysis of Human Glucuronyltransferase 1 (2001) (1)
The Structure and Characterization of Type I P-45015, Gene as Major Steroid 15a-Hydroxylase and Its Comparison with Type I1 P-4501~~ Gene” (2001) (1)
Cohesin protein SMC 1 represses the nuclear receptor CAR-mediated synergistic activation of a human P 450 gene by xenobiotics (2006) (1)
RACK1 regulates PP2A‐mediated de‐phosphorylation of threonine 38 of the human nuclear xenobiotic receptor CAR (2010) (0)
Crystal structure of human cholesterol sulfotransferase (SULT2B1b) in the presence of DHEA and PAP (2003) (0)
Microsoft Word-91204411-file00 (2010) (0)
Masahiko Negishi Sequestering CAR in the Cytoplasm andNR 1 I 3 ) , Repressing Dephosphorylation Active / Androstane Receptor ( CAR ; Phosphorylated Nuclear Constitutive Active ERK 1 / 2 Protein Interacts with the Gene Regulation (2011) (0)
crystal structure of mouse alpha-1,4-N-acetylhexosaminyltransferase (EXTL2) in complex with UDPGalNAc (2003) (0)
Phosphorylated nuclear receptors as drug-targets (2019) (0)
MOL099341 746..757 (2015) (0)
Crystal Structure of human 3-O-Sulfotransferase-3 with bound PAP and tetrasaccharide substrate (2004) (0)
CRYSTAL STRUCTURE OF HUMAN ESTROGEN SULFOTRANSFERASE IN COMPLEX WITH IN-ACTIVE COFACTOR PAP AND 3,5,3',5'-TETRACHLORO-BIPHENYL-4,4'-DIOL (2003) (0)
Nuclear receptor CAR mediates xenochemical induction of the CYP2B gene. (1998) (0)
Phenobarbital Inactivates Insulin Receptor to Elicit CAR‐dependent Decrease or –Independent Increase of Hepatic Gluconeogenesis (2015) (0)
EFFECT OF POSTNATAL EXPOSURE OF CIMETIDINE ON BLOOD TESTOSTERONE LEVEL AND HEPATIC MICROSOMAL TESTOSTERONE HYDROXYLATION ACTIVITY IN THE RAT (1984) (0)
Novel mechanism of CAR-mediated CYP2B6 induction (2004) (0)
Nuclear translocation of CAR is dependent on ubiquitination and proteasome‐mediated degradation of CAR cytoplasmic retention protein (CCRP) (2006) (0)
Nuclear xenobiotic receptor PXR locks co-repressor SMRT onto the CYP24A1 promoter to attenuate vitamin D 3 activation (2008) (0)
Preparation of Rough and Smooth Microsomes (2003) (0)
Bioactivation of aflatoxin G1 and inhibition of affatoxin B1 toxicity in yeast cells expressing mouse CYP2A enzymes (1995) (0)
Crystal structure of a hemagglutinin component (HA1) from type C Clostridium botulinum (2004) (0)
Nuclear Receptor PXR; a Novel Glucose Sensor That Regulates Hepatic Gluconeogenesis (2015) (0)
THE SULFOTRANSFERASE DOMAIN OF HUMAN HAPARIN SULFATE N-DEACETYLASE/N-SULFOTRANSFERASE (1999) (0)
The K+ Channel KCNK1: CAR‐mediated Gene Regulation of Male‐specific Induction by PB and Hepatic Hypertrophy (2011) (0)
Title : Phenobarbital and insulin reciprocate activation of the nuclear receptor CAR through the insulin receptor (2016) (0)
Mouse Liver Testosterone 15 wHydroxylase ( Cytochrome P-450 & (2001) (0)
Alteration of the substrate specificity of mouse 2A P450s by a mutation of residue-209: steroid-binding site and orientation (1992) (0)
ESTROGEN SULFOTRANSFERASE WITH INACTIVE COFACTOR PAP AND VANADATE (1999) (0)
Nuclear Receptors CAR, ERα and RORα Communicate via Phosphorylation to Differentially Regulate the SULT1E1 Gene Expression in Diabetic and Nondiabetic Human Livers (2020) (0)
Turnover of enzyme proteins in microsomal membrane. (1973) (0)
ESTROGEN SULFOTRANSFERASE WITH BOUND INACTIVE COFACTOR PAP AND 17-BETA ESTRADIOL (1998) (0)
The human sulfotransferase SULT1A1 gene is regulated in a synergistic manner by GA binding protein and Sp1 (2004) (0)
Crystal Structure of human 3-O-Sulfotransferase-3 with bound PAP (2004) (0)
Nuclear receptor CAR-mediated signals responsible for hepatocellular carcinoma (2008) (0)
Study on Electrochemical Anticorrosive Action of Pigments (1956) (0)
The constitutive androstane receptor mediates phenytoin induction of cyp2c37 (2006) (0)
Epidermal Growth Factor Receptor: The Phenobarbital Receptor that Elicits CAR Activation Signal for P450 Induction (2014) (0)
ESTROGEN SULFOTRANSFERASE WITH PAP (1998) (0)
Serum and glucocorticoid-regulated kinase 2 determines drug-activated PXR to induce gluconeogenesis in human liver cells (2013) (0)
EVIDENCE FOR TRANSCRIPTIONAL CONTROL OF CYTOCHROME PI-450 INDUCTION BY USE OF A CLONED DNA SEQUENCE* (2001) (0)
Azine derivative, process for its preparation, containing nematic liquid crystal composition and liquid crystal display device containing this (1997) (0)
Structural analysis of chondroitin polymerase from Escherichia coli K4 (2011) (0)
CRYSTAL STRUCTURE OF THE HUMAN HYDROXYSTEROID SULFOTRANSFERASE IN THE PRESENCE OF PAP (2000) (0)
Regulation of gene expression by CAR: an update (2015) (0)
Crystal structure of heparan sulfate 3-O-sulfotransferase isoform 1 in the presence of PAP (2004) (0)
p38 MAPK signaling determines CAR‐mediated activation of the CYP2B genes by xenobiotics (2012) (0)
HUMAN SULT1A3 WITH SULFATE BOUND (1999) (0)
DRUG INDUCTION OF P450 GENES: HISTORY, MECHANISM, AND IMPLICATION (2001) (0)
Characterization of a cloned dna sequence associated with the murine ah locus and a 3-methylcholanthrene-induced form of cytochrome p450. Abstr. (1981) (0)
Crystal Structure of human cholesterol sulfotransferase (SULT2B1b) in the presence of PAP and pregnenolone (2003) (0)
human beta 1,3-glucuronyltransferase I (GlcAT-I) in complex with UDP and GAL-GAL(6-SO4)-XYL(2-PO4)-O-SER (2008) (0)
Nuclear receptor CAR-ERα signaling regulates the estrogen sulfotransferase gene in the liver (2020) (0)
Estrogen receptor α phosphorylated at Ser216 confers inflammatory function to mouse microglia (2020) (0)
CRYSTAL STRUCTURE OF HUMAN ESTROGEN SULFOTRANSFERASE V269E MUTANT IN THE PRESENCE OF PAPS (2002) (0)
Gene regulation of human SULT1A sulfotransferases (2003) (0)
RXRα Phosphorylation at Threonine 167 Coordinates Energy Metabolism in Mice (2017) (0)
Nuclear Pregnane X Receptor Transduces Glucose Signal to Suppress Estrogen Sulfotransferase Gene in Human Liver Cells (2020) (0)
Crystal structure of mouse alpha-1,4-N-acetylhexosaminyltransferase (EXTL2) with UDP and GlcUAb(1-3)Galb(1-O)-naphthalenelmethanol an acceptor substrate analog (2003) (0)
Crystal structure of mouse alpha-1,4-N-acetylhexosaminyltransferase (EXTL2) (2003) (0)
Structural Biology of Sulfotransferase (2000) (0)
The Peripheral Benzodiazepine Receptor Ligand PK 11195 is a Novel Antagonist of Human Constitutive Androstane Receptor (2008) (0)
Ser815 Phosphorylation stabilizes the androgen receptor homodimer and stimulates ER-stress induced cell death. (2022) (0)

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