Masahiko Negishi
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Computer Science
Masahiko Negishi's Degrees
- PhD Computer Science University of Tokyo
- Masters Computer Science University of Tokyo
- Bachelors Computer Science University of Tokyo
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(Suggest an Edit or Addition)Masahiko Negishi's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The Nuclear Orphan Receptor CAR-Retinoid X Receptor Heterodimer Activates the Phenobarbital-Responsive Enhancer Module of the CYP2B Gene (1998) (742)
- The Repressed Nuclear Receptor CAR Responds to Phenobarbital in Activating the Human CYP2B6 Gene* (1999) (679)
- Phenobarbital-Responsive Nuclear Translocation of the Receptor CAR in Induction of the CYP2B Gene (1999) (559)
- Regulation of cytochrome P450 (CYP) genes by nuclear receptors. (2000) (498)
- Diverse roles of the nuclear orphan receptor CAR in regulating hepatic genes in response to phenobarbital. (2002) (473)
- CAR and PXR: The xenobiotic-sensing receptors (2007) (423)
- The phenobarbital response enhancer module in the human bilirubin UDP‐glucuronosyltransferase UGT1A1 gene and regulation by the nuclear receptor CAR (2001) (378)
- Phenobarbital response elements of cytochrome P450 genes and nuclear receptors. (2001) (376)
- Alteration of mouse cytochrome P450coh substrate specificity by mutation of a single amino-acid residue (1989) (370)
- The Orphan Nuclear Receptor Constitutive Active/Androstane Receptor Is Essential for Liver Tumor Promotion by Phenobarbital in Mice (2004) (343)
- Nuclear Receptors CAR and PXR Cross Talk with FOXO1 To Regulate Genes That Encode Drug-Metabolizing and Gluconeogenic Enzymes (2004) (323)
- Relative Activation of Human Pregnane X Receptor versus Constitutive Androstane Receptor Defines Distinct Classes of CYP2B6 and CYP3A4 Inducers (2007) (301)
- Complementary Roles of Farnesoid X Receptor, Pregnane X Receptor, and Constitutive Androstane Receptor in Protection against Bile Acid Toxicity* (2003) (295)
- Structure and function of sulfotransferases. (2001) (290)
- Developmental exposure to diethylstilbestrol elicits demethylation of estrogen-responsive lactoferrin gene in mouse uterus. (1997) (280)
- Genetic mechanisms controlling the induction of polysubstrate monooxygenase (P-450) activities. (1981) (262)
- Crystal structure of estrogen sulphotransferase (1997) (240)
- A Novel Distal Enhancer Module Regulated by Pregnane X Receptor/Constitutive Androstane Receptor Is Essential for the Maximal Induction of CYP2B6 Gene Expression* (2003) (224)
- Induction of Human CYP2C9 by Rifampicin, Hyperforin, and Phenobarbital Is Mediated by the Pregnane X Receptor (2004) (223)
- Differential Regulation of Hepatic CYP2B6 and CYP3A4 Genes by Constitutive Androstane Receptor but Not Pregnane X Receptor (2006) (199)
- Identification of a defect in the UGT1A1 gene promoter and its association with hyperbilirubinemia. (2002) (199)
- Cytoplasmic Localization of Pregnane X Receptor and Ligand-dependent Nuclear Translocation in Mouse Liver* (2004) (191)
- Human CYP2C8 Is Transcriptionally Regulated by the Nuclear Receptors Constitutive Androstane Receptor, Pregnane X Receptor, Glucocorticoid Receptor, and Hepatic Nuclear Factor 4α (2005) (190)
- Identification of constitutive androstane receptor and glucocorticoid receptor binding sites in the CYP2C19 promoter. (2003) (186)
- Cytoplasmic accumulation of the nuclear receptor CAR by a tetratricopeptide repeat protein in HepG2 cells. (2003) (186)
- Regulation of CYP2B6 in primary human hepatocytes by prototypical inducers. (2004) (185)
- Drug-activated nuclear receptors CAR and PXR (2003) (179)
- Nuclear Pregnane X Receptor Cross-talk with FoxA2 to Mediate Drug-induced Regulation of Lipid Metabolism in Fasting Mouse Liver* (2007) (174)
- Phenobarbital Indirectly Activates the Constitutive Active Androstane Receptor (CAR) by Inhibition of Epidermal Growth Factor Receptor Signaling (2013) (172)
- Identification of the nuclear receptor CAR:HSP90 complex in mouse liver and recruitment of protein phosphatase 2A in response to phenobarbital (2003) (167)
- Activation by diverse xenochemicals of the 51-base pair phenobarbital-responsive enhancer module in the CYP2B10 gene. (1998) (166)
- The Peptide Near the C Terminus Regulates Receptor CAR Nuclear Translocation Induced by Xenochemicals in Mouse Liver (2001) (161)
- Heparan/Chondroitin Sulfate Biosynthesis (2000) (160)
- Regulation of human CYP2C9 by the constitutive androstane receptor: discovery of a new distal binding site. (2002) (159)
- Estrogen activation of the nuclear orphan receptor CAR (constitutive active receptor) in induction of the mouse Cyp2b10 gene. (2000) (154)
- The Ah locus: Correlation of intranuclear appearance of inducer-receptor complex with induction of cytochrome P1-450 mRNA (1982) (149)
- Conserved structural motifs in the sulfotransferase family. (1998) (149)
- Characterization of a Phenobarbital-responsive Enhancer Module in Mouse P450 Cyp2b10 Gene* (1997) (148)
- CAR, driving into the future. (2004) (146)
- Human Constitutive Androstane Receptor Mediates Induction of CYP2B6 Gene Expression by Phenytoin* (2004) (146)
- The roles of nuclear receptors CAR and PXR in hepatic energy metabolism. (2008) (142)
- Estrogen Receptor α Mediates 17α-Ethynylestradiol Causing Hepatotoxicity* (2006) (137)
- Synthesis and insertion of cytochrome P-450 into endoplasmic reticulum membranes. (1980) (133)
- Transcriptional Regulation of Human UGT1A1 Gene Expression: Activated Glucocorticoid Receptor Enhances constitutive Androstane Receptor/Pregnane X Receptor-Mediated UDP-Glucuronosyltransferase 1A1 Regulation with Glucocorticoid Receptor-Interacting Protein 1 (2005) (132)
- Structural gene products of the Ah locus. Genetic and immunochemical evidence for two forms of mouse liver cytochrome P-450 induced by 3-methylcholanthrene. (1979) (130)
- Human nuclear pregnane X receptor cross-talk with CREB to repress cAMP activation of the glucose-6-phosphatase gene. (2007) (125)
- Crystal Structure of the Sulfotransferase Domain of Human Heparan Sulfate N-Deacetylase/ N-Sulfotransferase 1* (1999) (123)
- Multiple forms of cytochrome P-450 and the importance of molecular biology and evolution. (1982) (122)
- Dephosphorylation of Threonine 38 Is Required for Nuclear Translocation and Activation of Human Xenobiotic Receptor CAR (NR1I3)* (2009) (122)
- Phenobarbital-elicited activation of nuclear receptor CAR in induction of cytochrome P450 genes. (2000) (120)
- Transcriptional regulation of cytochrome p450 2B genes by nuclear receptors. (2003) (118)
- The Nuclear Receptors Constitutive Androstane Receptor and Pregnane X Receptor Cross-Talk with Hepatic Nuclear Factor 4α to Synergistically Activate the Human CYP2C9 Promoter (2005) (116)
- Characterization of Phenobarbital-inducible Mouse Cyp2b10 Gene Transcription in Primary Hepatocytes (*) (1996) (112)
- The environmental pollutant 1,1-dichloro-2,2-bis (p-chlorophenyl)ethylene induces rat hepatic cytochrome P450 2B and 3A expression through the constitutive androstane receptor and pregnane X receptor. (2003) (110)
- Crystal Structure of an α1,4-N-Acetylhexosaminyltransferase (EXTL2), a Member of the Exostosin Gene Family Involved in Heparan Sulfate Biosynthesis* (2003) (106)
- The dimerization motif of cytosolic sulfotransferases (2001) (105)
- Protein serine/threonine phosphatase inhibitors suppress phenobarbital-induced Cyp2b10 gene transcription in mouse primary hepatocytes. (1998) (104)
- Crystal structure of SULT2A3, human hydroxysteroid sulfotransferase (2000) (104)
- The Peripheral Benzodiazepine Receptor Ligand 1-(2-Chlorophenyl-methylpropyl)-3-isoquinoline-carboxamide Is a Novel Antagonist of Human Constitutive Androstane Receptor (2008) (103)
- Crystal structure of human catecholamine sulfotransferase. (1999) (100)
- Mutations affecting the regulation of transcription of the cytochrome P1-450 gene in the mouse Hepa-1 cell line. (1985) (100)
- Mouse steroid 15 alpha-hydroxylase gene family: identification of type II P-450(15)alpha as coumarin 7-hydroxylase. (1989) (99)
- The Sulfuryl Transfer Mechanism (1998) (96)
- The Ah locus, a multigene family necessary for survival in a chemically adverse environment: comparison with the immune system. (1982) (96)
- A DNA methylation site in the male-specific P450 (Cyp 2d-9) promoter and binding of the heteromeric transcription factor GABP (1995) (94)
- Role of constitutive androstane receptor in the in vivo induction of Mrp3 and CYP2B1/2 by phenobarbital. (2002) (93)
- Structural Analysis of the Sulfotransferase (3-O-Sulfotransferase Isoform 3) Involved in the Biosynthesis of an Entry Receptor for Herpes Simplex Virus 1* (2004) (92)
- Purification and characterization of heterologously expressed mouse CYP2A5 and CYP2G1: role in metabolic activation of acetaminophen and 2,6-dichlorobenzonitrile in mouse olfactory mucosal microsomes. (1998) (92)
- Nuclear receptor CAR as a regulatory factor for the sexually dimorphic induction of CYB2B1 gene by phenobarbital in rat livers. (2001) (91)
- Glucocorticoid receptor enhancement of pregnane X receptor-mediated CYP2B6 regulation in primary human hepatocytes. (2003) (89)
- Estrogen receptor alpha mediates 17alpha-ethynylestradiol causing hepatotoxicity. (2006) (88)
- Nuclear receptors CAR and PXR in the regulation of hepatic metabolism (2006) (88)
- Molecular characterization of a testis-specific estrogen sulfotransferase and aberrant liver expression in obese and diabetogenic C57BL/KsJ-db/db mice. (1995) (87)
- The structure, function, and regulation of cytochrome P450 2A enzymes. (1997) (86)
- New insights on the xenobiotic-sensing nuclear receptors in liver diseases--CAR and PXR--. (2008) (82)
- Pretranslational regulation of sex-dependent testosterone hydroxylases by growth hormone in mouse liver. (1986) (82)
- Extracellular Signal-Regulated Kinase Is an Endogenous Signal Retaining the Nuclear Constitutive Active/Androstane Receptor (CAR) in the Cytoplasm of Mouse Primary Hepatocytes (2007) (78)
- IDENTIFICATION OF HMG-CoA REDUCTASE INHIBITORS AS ACTIVATORS FOR HUMAN, MOUSE AND RAT CONSTITUTIVE ANDROSTANE RECEPTOR (2005) (76)
- Serine 202 Regulates the Nuclear Translocation of Constitutive Active/Androstane Receptor (2006) (74)
- Regulatory DNA elements of phenobarbital‐responsive cytochrome P450 CYP2B genes (1998) (74)
- The role of the nuclear receptor CAR as a coordinate regulator of hepatic gene expression in defense against chemical toxicity. (2003) (74)
- The role of the nuclear receptor constitutive androstane receptor in the pathogenesis of non-alcoholic steatohepatitis (2006) (74)
- Reciprocal regulation of sex-dependent expression of testosterone 15 alpha-hydroxylase (P-450(15 alpha)) in liver and kidney of male mice by androgen. Evidence for a single gene. (1988) (74)
- Mouse decay-accelerating factor: selective and tissue-specific induction by estrogen of the gene encoding the glycosylphosphatidylinositol-anchored form. (1996) (73)
- Crystal Structure of the Human Estrogen Sulfotransferase-PAPS Complex (2002) (71)
- Phenobarbital Confers its Diverse Effects by Activating the Orphan Nuclear Receptor Car (2006) (70)
- Crystal Structure and Mutational Analysis of Heparan Sulfate 3-O-Sulfotransferase Isoform 1* (2004) (70)
- 2-O-Phosphorylation of Xylose and 6-O-Sulfation of Galactose in the Protein Linkage Region of Glycosaminoglycans Influence the Glucuronyltransferase-I Activity Involved in the Linkage Region Synthesis* (2008) (69)
- Sexually dimorphic DNA demethylation in the promoter of the Slp (sex-limited protein) gene in mouse liver. (1995) (69)
- Cellular localization and regulation of expression of testicular estrogen sulfotransferase. (1997) (69)
- Structural flexibility and functional versatility of mammalian P450 enzymes (1996) (68)
- Structural gene product of the [Ah] complex. Evidence for transcriptional control of cytochrome P1-450 induction by use of a cloned DNA sequence. (1981) (68)
- Structural analysis by X-ray crystallography and calorimetry of a haemagglutinin component (HA1) of the progenitor toxin from Clostridium botulinum. (2003) (68)
- The structure and characterization of type I P-450(15) alpha gene as major steroid 15 alpha-hydroxylase and its comparison with type II P-450(15) alpha gene. (1989) (67)
- Developmental action of estrogen receptor-alpha feminizes the growth hormone-Stat5b pathway and expression of Cyp2a4 and Cyp2d9 genes in mouse liver. (1999) (67)
- Phenobarbital induction of drug/steroid-metabolizing enzymes and nuclear receptor CAR. (2003) (66)
- SLC13A5 Is a Novel Transcriptional Target of the Pregnane X Receptor and Sensitizes Drug-Induced Steatosis in Human Liver (2015) (65)
- Crystallographic analysis of a hydroxylated polychlorinated biphenyl (OH-PCB) bound to the catalytic estrogen binding site of human estrogen sulfotransferase. (2003) (64)
- Crystal Structure of β1,3-Glucuronyltransferase I in Complex with Active Donor Substrate UDP-GlcUA* (2002) (63)
- Mouse liver testosterone 15 alpha-hydroxylase (cytochrome P-450(15) alpha). Purification, regioselectivity, stereospecificity, and sex-dependent expression. (1984) (63)
- Identification of Ginkgo biloba as a Novel Activator of Pregnane X Receptor (2008) (62)
- Regulation of gene expression by CAR: an update (2015) (59)
- A nuclear factor (NF2d9) that binds to the male-specific P450 (Cyp 2d-9) gene in mouse liver (1995) (59)
- Substrate Gating Confers Steroid Specificity to Estrogen Sulfotransferase* (1999) (57)
- Crystal structure‐based studies of cytosolic sulfotransferase (2001) (55)
- Rip locus: regulation of female-specific isozyme (I-P-450(16 alpha) of testosterone 16 alpha-hydroxylase in mouse liver, chromosome localization, and cloning of P-450 cDNA. (1988) (55)
- Mouse pulmonary cytochrome P-450 naphthalene hydroxylase: cDNA cloning, sequence, and expression in Saccharomyces cerevisiae. (1991) (55)
- Discovery of estrogen sulfotransferase inhibitors from a purine library screen. (2001) (54)
- A role of Lys614 in the sulfotransferase activity of human heparan sulfate N‐deacetylase/N‐sulfotransferase (1998) (54)
- Promoter CpG methylation of Hox‐a10 and Hox‐a11 in mouse uterus not altered upon neonatal diethylstilbestrol exposure * (2001) (54)
- Active ERK1/2 Protein Interacts with the Phosphorylated Nuclear Constitutive Active/Androstane Receptor (CAR; NR1I3), Repressing Dephosphorylation and Sequestering CAR in the Cytoplasm* (2011) (54)
- Role of CYP2A5 and 2G1 in acetaminophen metabolism and toxicity in the olfactory mucosa of the Cyp1a2(-/-) mouse. (1998) (53)
- Crystal Structure of Human Cholesterol Sulfotransferase (SULT2B1b) in the Presence of Pregnenolone and 3′-Phosphoadenosine 5′-Phosphate (2003) (53)
- Isolation and characterization of a cloned DNA sequence associated with the murine Ah locus and a 3-methylcholanthrene-induced form of cytochrome P-450. (1981) (53)
- Flame retardant BDE-47 effectively activates nuclear receptor CAR in human primary hepatocytes. (2014) (53)
- Nuclear Receptor CAR Represses TNFα-Induced Cell Death by Interacting with the Anti-Apoptotic GADD45B (2010) (52)
- Statin-activated nuclear receptor PXR promotes SGK2 dephosphorylation by scaffolding PP2C to induce hepatic gluconeogenesis (2015) (52)
- The constitutive active/androstane receptor regulates phenytoin induction of Cyp2c29. (2004) (52)
- Structural gene products of the Ah complex. Increases in large mRNA from mouse liver associated with cytochrome P1-450 induction by 3-methylcholanthrene. (1981) (51)
- Pregnane X Receptor PXR Activates the GADD45β Gene, Eliciting the p38 MAPK Signal and Cell Migration* (2010) (51)
- Novel CAR-mediated Mechanism for Synergistic Activation of Two Distinct Elements within the Human Cytochrome P450 2B6 Gene in HepG2 Cells* (2005) (50)
- Glucosaminylglycan biosynthesis: what we can learn from the X-ray crystal structures of glycosyltransferases GlcAT1 and EXTL2. (2003) (50)
- Gene family of male-specific testosterone 16 alpha-hydroxylase (C-P-450(16) alpha) in mouse liver: cDNA sequences, neonatal imprinting, and reversible regulation by androgen. (1987) (49)
- Posttranscriptional regulation of coumarin 7-hydroxylase induction by xenobiotics in mouse liver: mRNA stabilization by pyrazole. (1991) (49)
- Interaction of aflatoxin B1 with cytochrome P450 2A5 and its mutants: correlation with metabolic activation and toxicity. (1997) (49)
- Regulation of the human UGT1A1 gene by nuclear receptors constitutive active/androstane receptor, pregnane X receptor, and glucocorticoid receptor. (2005) (49)
- Engineering mouse P450coh to a novel corticosterone 15 alpha-hydroxylase and modeling steroid-binding orientation in the substrate pocket. (1993) (48)
- Mechanism of induction of cytochrome p450 enzymes by the proestrogenic endocrine disruptor pesticide-methoxychlor: interactions of methoxychlor metabolites with the constitutive androstane receptor system. (2001) (48)
- Mouse liver testosterone 16 alpha-hydroxylase (cytochrome P-450(16) alpha). Purification, regioselectivity, stereospecificity, and immunochemical characterization. (1984) (48)
- The Human Sulfotransferase SULT1A1 Gene Is Regulated in a Synergistic Manner by Sp1 and GA Binding Protein (2004) (48)
- Phenytoin Induction of the Cyp2c37 Gene Is Mediated by the Constitutive Androstane Receptor (2006) (47)
- Separation of acetanilide and its hydroxylated metabolites and quantitative determination of "acetanilide 4-hydroxylase activity" by high-pressure liquid chromatography. (1979) (46)
- Structural function of residue-209 in coumarin 7-hydroxylase (P450coh). Enzyme-kinetic studies and site-directed mutagenesis. (1991) (46)
- PPP1R16A, The Membrane Subunit of Protein Phosphatase 1β, Signals Nuclear Translocation of the Nuclear Receptor Constitutive Active/Androstane Receptor (2008) (46)
- Site-directed mutagenesis of mouse steroid 7 alpha-hydroxylase (cytochrome P-450(7) alpha): role of residue-209 in determining steroid-cytochrome P-450 interaction. (1993) (46)
- Pregnane X receptor regulates drug metabolism and transport in the vasculature and protects from oxidative stress (2011) (46)
- Are estrogens carcinogenic during development of the testes? (1998) (45)
- Orphan nuclear receptor constitutive active/androstane receptor-mediated alterations in DNA methylation during phenobarbital promotion of liver tumorigenesis. (2007) (45)
- Biosynthesis of cytochrome P-450 on membrane-bound ribosomes and its subsequent incorporation into rough and smooth microsomes in rat hepatocytes (1979) (45)
- Alteration of high and low spin equilibrium by a single mutation of amino acid 209 in mouse cytochromes P450. (1991) (44)
- Purification and partial characterization of hepatic microsomal cytochrome P-450s from phenobarbital- and 3-methylcholanthrene-treated rats. (1979) (44)
- Effect of various cations on the acidity of p-sulfonatocalixarenes (1998) (44)
- Liganded pregnane X receptor represses the human sulfotransferase SULT1E1 promoter through disrupting its chromatin structure (2011) (42)
- Distribution and induction of cytochrome P-450 in rat liver nuclear envelope (1981) (41)
- Differential UGT1A1 Induction by Chrysin in Primary Human Hepatocytes and HepG2 Cells (2005) (41)
- Mouse glycine N-methyltransferase is sexually dimorphic and regulated by growth hormone. (1997) (41)
- The Nuclear Receptor Constitutively Active/Androstane Receptor Regulates Type 1 Deiodinase and Thyroid Hormone Activity in the Regenerating Mouse Liver (2007) (40)
- Gene family of male-specific testosterone 16 alpha-hydroxylase (C-P-450(16 alpha)) in mice. Organization, differential regulation, and chromosome localization. (1989) (39)
- Cytochrome P4502A5 expression and inducibility by phenobarbital is modulated by cAMP in mouse primary hepatocytes. (1994) (39)
- Characterization of cytochrome P2-450 (20-S) mRNA. Association with the P1-450 genomic gene and differential response to the inducers 3-methylcholanthrene and isosafrole. (1983) (38)
- Primary structures of multiple forms of cytochrome P-450 isozyme 2 derived from rabbit pulmonary and hepatic cDNAs. (1988) (37)
- Inter-α-trypsin Inhibitor Promotes Bronchial Epithelial Repair after Injury through Vitronectin Binding* (2009) (37)
- Coordinated Regulation of Nuclear Receptor CAR by CCRP/DNAJC7, HSP70 and the Ubiquitin-Proteasome System (2014) (36)
- Garlic Extract Diallyl Sulfide (DAS) Activates Nuclear Receptor CAR to Induce the Sult1e1 Gene in Mouse Liver (2011) (36)
- Activation volume and energetic properties of the binding of CO to hemoproteins. (1994) (36)
- Mouse steroid sulfotransferases: substrate specificity and preliminary X-ray crystallographic analysis. (1998) (36)
- Structural gene products of the murine Ah complex. Differences in ontogenesis and glucosamine incorporation between liver microsomal cytochromes P1-450 and P-448 induced by polycyclic aromatic compounds. (2005) (36)
- Crystal Structure of the Human Estrogen Sulfotransferase-PAPS Complex EVIDENCE FOR CATALYTIC ROLE OF Ser IN THE SULFURYL TRANSFER REACTION* (2002) (35)
- Quantitation of hepatic cytochrome P1-450 mRNA with the use of a cloned DNA probe. Effects of various P-450 inducers in C57BL/6N and DBA/2N mice. (1982) (35)
- Cloning and nucleotide sequence of a novel, male-predominant carboxylesterase in mouse liver. (1993) (34)
- Sulfotransferase genes: Regulation by nuclear receptors in response to xeno/endo-biotics (2013) (34)
- Nuclear Xenobiotic Receptor Pregnane X Receptor Locks Corepressor Silencing Mediator for Retinoid and Thyroid Hormone Receptors (SMRT) onto the CYP24A1 Promoter to Attenuate Vitamin D3 Activation (2009) (34)
- Molecular characterization of the murine Coh locus: an amino acid difference at position 117 confers high and low coumarin 7-hydroxylase activity in P450coh. (1992) (33)
- Structure and Function of HNK-1 Sulfotransferase (1999) (33)
- Isosafrole-induced cytochrome P2-450 in DBA/2N mouse liver. Characterization and genetic control of induction. (1984) (33)
- Structural flexibility and functional versatility of cytochrome P450 and rapid evolution. (1996) (33)
- Sexual dimorphism of testosterone 15 alpha-hydroxylase mRNA levels in mouse liver. cDNA cloning and regulation. (1985) (33)
- Molecular engineering of microsomal P450 2a-4 to a stable, water-soluble enzyme. (1995) (32)
- cDNA cloning and sequence of CYP2C29 encoding P-450 MUT-2, a microsomal aldehyde oxygenase. (1994) (32)
- Nuclear Receptor CAR Requires Early Growth Response 1 to Activate the Human Cytochrome P450 2B6 Gene* (2008) (32)
- Regulation of Cyp2a5 transcription in mouse primary hepatocytes: roles of hepatocyte nuclear factor 4 and nuclear factor I. (2004) (31)
- Dietary flavonoids activate the constitutive androstane receptor (CAR). (2010) (31)
- Transcriptional regulation by HNF-4 of the steroid 15α-hydroxylase P450 (Cyp2a-4) gene in mouse liver (1997) (31)
- Phenobarbital Meets Phosphorylation of Nuclear Receptors (2017) (31)
- Induction of microsomal dimethylnitrosamine demethylase by pyrazole. (1982) (30)
- Phosphorylated Nuclear Receptor CAR Forms a Homodimer To Repress Its Constitutive Activity for Ligand Activation (2017) (30)
- Species-specific responses of constitutively active receptor (CAR)-CYP2B coupling: lack of CYP2B inducer-responsive nuclear translocation of CAR in marine teleost, scup (Stenotomus chrysops). (2002) (30)
- Roles of residues 129 and 209 in the alteration by cytochrome b5 of hydroxylase activities in mouse 2A P450S. (1992) (30)
- PXR cross-talks with internal and external signals in physiological and pathophysiological responses (2013) (29)
- Site of biosynthesis of cytochrome P450 in hepatocytes of phenobarbital treated rats. (1976) (28)
- Serum- and Glucocorticoid-Regulated Kinase 2 Determines Drug-Activated Pregnane X Receptor to Induce Gluconeogenesis in Human Liver Cells (2014) (28)
- Molecular cloning and characterization of a novel nuclear protein kinase in mice. (1998) (27)
- Nuclear receptor CAR (NR1I3) is essential for DDC-induced liver injury and oval cell proliferation in mouse liver (2011) (26)
- The Antiapoptotic Factor Growth Arrest and DNA-Damage-Inducible 45 β Regulates the Nuclear Receptor Constitutive Active/Androstane Receptor-Mediated Transcription (2008) (26)
- Structures and characterization of sex-specific mouse cytochrome P-450 genes as members within a large family. Duplication boundary and evolution. (1991) (26)
- Pregnane X Receptor Represses HNF4α Gene to Induce Insulin-Like Growth Factor–Binding Protein IGFBP1 that Alters Morphology of and Migrates HepG2 Cells (2015) (25)
- Activation of aflatoxin B1 by mouse CYP2A enzymes and cytotoxicity in recombinant yeast cells. (1994) (25)
- Characterization of a cDNA for rat P-450g, a highly polymorphic, male-specific cytochrome in the P-450IIC subfamily. (1989) (25)
- Residue threonine 350 confers steroid hormone responsiveness to the mouse nuclear orphan receptor CAR. (2002) (24)
- The Chondroitin Polymerase K4CP and the Molecular Mechanism of Selective Bindings of Donor Substrates to Two Active Sites* (2008) (24)
- Early growth response 1 loops the CYP2B6 promoter for synergistic activation by the distal and proximal nuclear receptors CAR and HNF4α (2009) (23)
- Sexual dimorphisms in zonal gene expression in mouse liver. (2013) (23)
- Overexpression of a cytochrome P-450 of the 2a family (Cyp2a-5) in chemically induced hepatomas from female mice. (1994) (23)
- The Roles of Co-Chaperone CCRP/DNAJC7 in Cyp2b10 Gene Activation and Steatosis Development in Mouse Livers (2014) (23)
- Heparan sulphate N-sulphotransferase activity: reaction mechanism and substrate recognition. (2003) (22)
- Localization of the nuclear receptor CAR at the cell membrane of mouse liver (2005) (22)
- Similarities between mouse and rat-liver microsomal cytochromes P-450 induced by 3-methylcholanthrene. Evidence from catalytic, immunologic, and recombinant DNA studies. (1982) (22)
- Comparison between cobalt and pyrazole in the increased expression of coumarin 7-hydroxylase in mouse liver. (1991) (22)
- Retinoic acids repress constitutive active receptor-mediated induction by 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene of the CYP2B10 gene in mouse primary hepatocytes. (2002) (21)
- Serine 216 Phosphorylation of Estrogen Receptor α in Neutrophils: Migration and Infiltration into the Mouse Uterus (2013) (21)
- A trans-acting locus regulates transcriptional repression of the female-specific steroid 15 alpha-hydroxylase gene in male mice. (1993) (21)
- Phosphorylation of Farnesoid X Receptor at Serine 154 Links Ligand Activation With Degradation. (2016) (21)
- Female-predominant expression of testosterone 16α-hydroxylase (“I”-P-45016α) and its repression in strain 129/J (1986) (20)
- Thr176 regulates the activity of the mouse nuclear receptor CAR and is conserved in the NR1I subfamily members PXR and VDR. (2005) (20)
- Localization of nascent NADPH-cytochrome c reductase in rat liver microsomes. (1975) (20)
- Expression of CAR in SW480 and HepG2 cells during G1 is associated with cell proliferation. (2008) (20)
- Nuclear receptor phosphorylation in xenobiotic signal transduction (2020) (20)
- Cytochrome P1-450 structural gene in mouse, rat, and rabbit: differences in DNA methylation and developmental expression of mRNA. (1982) (20)
- Structure of the mouse cytochrome P1-450 genomic gene. (1983) (19)
- p38 Mitogen–Activated Protein Kinase Regulates Nuclear Receptor CAR that Activates the CYP2B6 Gene (2013) (19)
- Inherent versatility of P-450 oxygenase. Conferring dehydroepiandrosterone hydroxylase activity to P-450 2a-4 by a single amino acid mutation at position 117. (1994) (19)
- Direct expression of fluorescent protein-tagged nuclear receptor CAR in mouse liver. (2002) (19)
- Chapter 13:Receptor-Mediated Regulation of Cytochromes P450 (2008) (19)
- Role of nuclear receptor CAR in carbon tetrachloride-induced hepatotoxicity. (2005) (18)
- Human SULT1A genes: cloning and activity assays of the SULT1A promoters. (2005) (18)
- Presence of apo-cytochrome beta 5 in microsomes from rat liver. (1970) (17)
- Interaction of the phosphorylated DNA-binding domain in nuclear receptor CAR with its ligand-binding domain regulates CAR activation (2017) (17)
- Altering the regiospecificity of androstenedione hydroxylase activity in P450s 2a-4/5 by a mutation of the residue at position 481. (1995) (17)
- INDUCTION OF GENES FOR METABOLISM AND TRANSPORT BY TRANS-STILBENE OXIDE IN LIVERS OF SPRAGUE-DAWLEY AND WISTAR-KYOTO RATS (2006) (17)
- Searching for the minimum energy path in the sulfuryl transfer reaction catalyzed by human estrogen sulfotransferase: Role of enzyme dynamics (2006) (17)
- Nuclear receptor CAR-regulated expression of the FAM84A gene during the development of mouse liver tumors. (2011) (17)
- Nuclear xenobiotic receptor PXR-null mouse exhibits hypophosphatemia and represses the Na/Pi-cotransporter SLC34A2 (2010) (16)
- Coordinated polypeptide synthesis and insertion of protoheme in cytochrome P-450 during development of endoplasmic reticulum membranes. (1978) (16)
- Phenobarbital and Insulin Reciprocate Activation of the Nuclear Receptor Constitutive Androstane Receptor through the Insulin Receptor (2016) (16)
- The roles of individual amino acids in altering substrate specificity of the P450 2a4/2a5 enzymes. (1996) (16)
- Phosphorylation of serine 212 confers novel activity to human estrogen receptor α (2012) (15)
- Glucose elicits serine/threonine kinase VRK1 to phosphorylate nuclear pregnane X receptor as a novel hepatic gluconeogenic signal. (2017) (15)
- Functional characterization of two cytochrome P-450s within the mouse, male-specific steroid 16 alpha-hydroxylase gene family: expression in mammalian cells and chimeric proteins. (1989) (15)
- Heparan sulfate biosynthesis: a theoretical study of the initial sulfation step by N-deacetylase/N-sulfotransferase. (2000) (15)
- The Structural Basis for a Coordinated Reaction Catalyzed by a Bifunctional Glycosyltransferase in Chondroitin Biosynthesis* (2012) (15)
- Multiple steroid-binding orientations: alteration of regiospecificity of dehydroepiandrosterone 2- and 7-hydroxylase activities of cytochrome P-450 2a-5 by mutation of residue 209. (1995) (14)
- Post-transcriptional regulation of coumarin 7-hydroxylase (P450coh) induction by xenobiotics in mouse liver: mRNA stabilization by pyrazole (1991) (14)
- The Nuclear Receptors Constitutive Active/Androstane Receptor and Pregnane X Receptor Activate the Cyp2c55 Gene in Mouse Liver (2010) (14)
- A specific cis-acting element regulates in vitro transcription of sex-dependent mouse steroid 16 alpha-hydroxylase (C-P450(16 alpha)) gene. (1990) (14)
- 3'-Phosphoadenosine 5'-phosphosulfate binding site of flavonol 3-sulfotransferase studied by affinity chromatography and 31P NMR. (1999) (14)
- p38 MAP Kinase Links CAR Activation and Inactivation in the Nucleus via Phosphorylation at Threonine 38 (2016) (14)
- Explicit water near the catalytic I helix Thr in the predicted solution structure of CYP2A4. (2003) (13)
- Alteration of the substrate specificity of mouse 2A P450s by the identity of residue-209: Steroid-binding site and orientation (1992) (13)
- Reciprocal size-effect relationship of the key residues in determining regio- and stereospecificities of DHEA hydroxylase activity in P450 2a5. (1997) (13)
- Photochemical Switching of Ferroelectric Liquid Crystals Using a Photoswitchable Chiral Dopant (1996) (13)
- Role of CYP2B in Phenobarbital-Induced Hepatocyte Proliferation in Mice (2017) (12)
- Two-step Mechanism That Determines the Donor Binding Specificity of Human UDP-N-acetylhexosaminyltransferase* (2005) (12)
- Characterization of testosterone 16 alpha-hydroxylase (I-P-450(16) alpha) induced by phenobarbital in mice. (1985) (12)
- Synthesis and Photochemical Switching of the Antiferroelectric Liquid Crystals Containing a Diazenediyl Group. (1996) (12)
- Structural alteration of mouse P450coh by mutation of glycine-207 to proline: spin equilibrium, enzyme kinetics, and heat sensitivity. (1993) (11)
- The early stage of labeling of microsomal membrane proteins in rat liver by radioactive amino acids. (1972) (11)
- Cohesin protein SMC1 represses the nuclear receptor CAR-mediated synergistic activation of a human P450 gene by xenobiotics. (2006) (11)
- Nuclear receptor CAR specifically activates the two-pore K+ channel Kcnk1 gene in male mouse livers, which attenuates phenobarbital-induced hepatic hyperplasia. (2013) (11)
- Characterization and regulation of sex-specific mouse steroid hydroxylase genes. (1990) (11)
- Nuclear receptor CAR-ERα signaling regulates the estrogen sulfotransferase gene in the liver (2020) (10)
- Nuclear Receptor CAR Suppresses GADD45B-p38 MAPK Signaling to Promote Phenobarbital-induced Proliferation in Mouse Liver (2018) (10)
- Role of a novel CAR-induced gene, TUBA8, in hepatocellular carcinoma cell lines. (2011) (10)
- Lack of the steroid 15 alpha-hydroxylase gene (Cyp2a-4) in wild mouse strain Mus spretus: rapid evolution of the P450 gene superfamily. (1994) (10)
- Estrogen receptor α phosphorylated at Ser216 confers inflammatory function to mouse microglia (2019) (9)
- Two steroid 15α-hydroxylase genes and a homologous gene family in mice (1990) (9)
- Expression of genes within mouse IIA and IID subfamilies: simultaneous measurement of homologous P450 mRNAs. (1991) (9)
- Phenobarbital‐induced phosphorylation converts nuclear receptor RORα from a repressor to an activator of the estrogen sulfotransferase gene Sult1e1 in mouse livers (2018) (9)
- Ligand induced dissociation of the AR homodimer precedes AR monomer translocation to the nucleus (2019) (9)
- Expression and subcellular distribution of mouse cytochrome P1-450 mRNA as determined by molecular hybridization with cloned P1-450 DNA. (1982) (9)
- Tissue-specific regulation of cytochrome P-450 dependent testosterone 15α-hydroxylase (1990) (9)
- Experimental and modelling study of semi-continuous emulsion copolymerization of styrene and acrylonitrile (1985) (9)
- Overexpression of the Rho‐guanine nucleotide exchange factor ECT2 inhibits nuclear translocation of nuclear receptor CAR in the mouse liver (2007) (8)
- Genetic regulation of estrogen-dependent repression of female-specific testosterone 16 alpha-hydroxylase (I-P-450(16 alpha) in male mouse liver: murine Ripr locus. (1988) (8)
- Sulfotransferase 4A1 Increases Its Expression in Mouse Neurons as They Mature (2018) (8)
- Characterization of a cDNA for the unexpressed form of cytochrome P-450g from the (-g) rat and differentiation of its mRNA from that of the (+g) phenotype using specific oligoprobes. (1990) (8)
- Estrogen Sulfotransferase (SULT1E1): Its Molecular Regulation, Polymorphisms, and Clinical Perspectives (2021) (8)
- Modulation of specificity and activity in mammalian cytochrome P-450. (1991) (8)
- Nuclear Receptor-Mediated Regulation of Cytochrome P450 Genes (2015) (8)
- A quantum mechanical study of the transfer of biological sulfate (1999) (7)
- Crystal Structure of the Human Estrogen Sulfotransferase-PAPS Complex EVIDENCE FOR CATALYTIC ROLE OF Ser (2002) (7)
- A phosphorylation-deficient mutant of retinoid X receptor α at Thr 167 alters fasting response and energy metabolism in mice (2019) (7)
- Genetic regulation of testosterone 15 alpha-hydroxylase (cytochrome P-450(15)alpha) in renal microsomes of female mice. (1986) (7)
- Characterization of specific donor binding to alpha1,4-N-acetylhexosaminyltransferase EXTL2 using isothermal titration calorimetry. (2006) (7)
- PXR Phosphorylated at Ser350 transduces a glucose signal to repress the estrogen sulfotransferase gene in human liver cells and fasting signal in mouse livers. (2020) (7)
- Structure-function modeling of the interactions of N-alkyl-N-hydroxyanilines with rat hepatic aryl sulfotransferase IV. (2000) (7)
- Co-Chaperone-Mediated Suppression of LPS-Induced Cardiac Toxicity Through NF&kgr;B Signaling (2017) (6)
- Design, Synthesis and Physical Properties of New Liquid Crystal Materials Having a Fluoro-Substituted Tetrahydronaphthalene Structure for Active Matrix LCD (2004) (6)
- CRYSTAL STRUCTURE OF BETA1,3-GLUCURONYLTRANSFERASE I IN COMPLEX WITH THE ACTIVE UDP-GLCUA DONOR (2002) (6)
- Sex-dependent expression of mouse testosterone 16 alpha-hydroxylase (cytochrome P-450(16) alpha): cDNA cloning and pretranslational regulation. (1985) (6)
- The nuclear receptor constitutive active/androstane receptor arrests DNA‐damaged human hepatocellular carcinoma Huh7 cells at the G2/M phase (2012) (5)
- BASIC EQUATIONS FOR SIMULATION OF SEMI-CONTINUOUS OPERATION OF EMULSION POLYMERIZATION (1983) (5)
- Phosphorylation of vaccinia-related kinase 1 at threonine 386 transduces glucose stress signal in human liver cells (2020) (5)
- Genetic Differences in Enzymes which Metabolize Drugs, Chemical Carcinogens, and Other Environmental Pollutants (1983) (5)
- Female-predominant expression of testosterone 16 alpha-hydroxylase ("I"-P-450(16)alpha) and its repression in strain 129/J. (1986) (5)
- mitogen activated protein kinase regulates nuclear receptor CAR that activates the CYP 2 B 6 gene (2013) (5)
- Environmental and genetic factors influencing drug metabolism and toxicity (1984) (4)
- Structural gene products of the murine ah locus: immunochemical evidence for two forms of liver p-450 induced by 3-methylcholanthrene. Abstr. (1979) (4)
- Glucocorticoid receptor dimerization in the cytoplasm might be essential for nuclear localization. (2021) (4)
- Ser100-Phosphorylated RORα Orchestrates CAR and HNF4α to Form Active Chromatin Complex in Response to Phenobarbital to Regulate Induction of CYP2B6 (2020) (4)
- Human constitutive androstane receptor represses liver cancer development and hepatoma cell proliferation by inhibiting erythropoietin signaling (2022) (4)
- GR Utilizes a Co-Chaperone Cytoplasmic CAR Retention Protein to Form an N/C Interaction (2018) (3)
- Sex-specific expression mechanism of hepatic estrogen inactivating enzyme and transporters in diabetic women. (2021) (3)
- Androgen receptor phosphorylated at Ser815: the expression and function in the prostate and tumor-derived cells. (2021) (3)
- RORα phosphorylation by casein kinase 1α as glucose signal to regulate estrogen sulfation in human liver cells (2020) (3)
- Design, Synthesis and Physical Properties of New Liquid Crystal Materials for Active Matrix LCD (2) (2001) (3)
- Nuclear pregnane X receptor cross-talks with CREB to repress cAMP activation of the glucose-6-phosphatase gene (2007) (3)
- Crystal structure of human pregnenolone sulfotransferase (SULT2B1a) in the presence of PAP (2003) (3)
- Cloning genes that encode inducible forms of P-450. (1984) (2)
- STRUCTURAL GENE PRODUCTS OF THE MURINE Ah LOCUS. IMMUNOCHEMICAL CHARACTERIZATION OF TWO FORMS OF P-450 INDUCED BY POLYCYCLIC AROMATIC COMPOUNDS (1980) (2)
- Cloning genes that encode drug-metabolizing enzymes: developmental pharmacology and teratology. (1983) (2)
- Detection and Functional Analysis of Estrogen Receptor α Phosphorylated at Serine 216 in Mouse Neutrophils. (2016) (2)
- Tissue-specific regulation of cytochrome P-450 dependent testosterone 15 alpha-hydroxylase. (1990) (2)
- Mice blocking Ser347 phosphorylation of pregnane x receptor develop hepatic fasting-induced steatosis and hypertriglyceridemia. (2022) (2)
- Two steroid 15 alpha-hydroxylase genes and a homologous gene family in mice. (1990) (2)
- Transcriptional regulation of human UGT1A1 gene expression: Activated GR enhances CAR/PXR-mediated UGT1A1 regulation with GRIP1 (2004) (1)
- CONSTITUTIVE ACTIVE RECEPTOR-MEDIATED INDUCTION BY 1 , 4-BIS [ 2-( 3 , 5-DICHLOROPYRIDYLOXY ) ] BENZENE OF THE CYP 2 B 10 GENE IN MOUSE PRIMARY HEPATOCYTES (2002) (1)
- ACTIVE ERK 1 / 2 INTERACTS WITH PHOSPHORYLATED NUCLEAR RECEPTOR CAR ( NR 1 I 3 ) REPRESSING DEPHOSPHORYLATION AND SEQUESTERING IT IN THE CYTOPLASM (2011) (1)
- Steroid hormone-dependent overexpression of cytochromes P450 2A in liver tumors of TGFα transgenic male mice (1997) (1)
- SUN-LB134 Androgen Receptor Phosphorylated at Serine 815 in Mouse and Human Prostates (2020) (1)
- Detection and Functional Analysis of Estrogen Receptor α Phosphorylated at Serine 216 in Mouse Neutrophils. (2022) (1)
- Repression of phenobarbital-responsive enhancer module in the Cyp2b10 gene by estrogen receptor-related receptor ERR (2000) (1)
- Design, Synthesis and Physical Properties of New Liquid Crystal Materials for Active Matrix LCD (1) (2001) (1)
- Isolation and characterization of the mouse P1-450 chromosomal gene. (1982) (1)
- Substrate specificities of cytochrome P-450, C-P-450(16)alpha and P-450(15)alpha, and contribution to steroid hydroxylase activities in mouse liver microsomes. (1988) (1)
- Immunoprecipitation Analyses of Estrogen Receptor α Phosphorylated at Serine 216 in the Mouse Liver. (2022) (1)
- The Nuclear Receptors CAR and PXR Activate the Cyp 2 c 55 Gene in Mouse Liver (2010) (1)
- Differential UGT 1 A 1 Induction by Chrysin in Primary Human Hepatocytes and HepG 2 Cells (2005) (1)
- Crystal Structure-Based Analysis of Human Glucuronyltransferase 1 (2001) (1)
- The Structure and Characterization of Type I P-45015, Gene as Major Steroid 15a-Hydroxylase and Its Comparison with Type I1 P-4501~~ Gene” (2001) (1)
- Cohesin protein SMC 1 represses the nuclear receptor CAR-mediated synergistic activation of a human P 450 gene by xenobiotics (2006) (1)
- RACK1 regulates PP2A‐mediated de‐phosphorylation of threonine 38 of the human nuclear xenobiotic receptor CAR (2010) (0)
- Crystal structure of human cholesterol sulfotransferase (SULT2B1b) in the presence of DHEA and PAP (2003) (0)
- Microsoft Word-91204411-file00 (2010) (0)
- Masahiko Negishi Sequestering CAR in the Cytoplasm andNR 1 I 3 ) , Repressing Dephosphorylation Active / Androstane Receptor ( CAR ; Phosphorylated Nuclear Constitutive Active ERK 1 / 2 Protein Interacts with the Gene Regulation (2011) (0)
- crystal structure of mouse alpha-1,4-N-acetylhexosaminyltransferase (EXTL2) in complex with UDPGalNAc (2003) (0)
- Phosphorylated nuclear receptors as drug-targets (2019) (0)
- MOL099341 746..757 (2015) (0)
- Crystal Structure of human 3-O-Sulfotransferase-3 with bound PAP and tetrasaccharide substrate (2004) (0)
- CRYSTAL STRUCTURE OF HUMAN ESTROGEN SULFOTRANSFERASE IN COMPLEX WITH IN-ACTIVE COFACTOR PAP AND 3,5,3',5'-TETRACHLORO-BIPHENYL-4,4'-DIOL (2003) (0)
- Nuclear receptor CAR mediates xenochemical induction of the CYP2B gene. (1998) (0)
- Phenobarbital Inactivates Insulin Receptor to Elicit CAR‐dependent Decrease or –Independent Increase of Hepatic Gluconeogenesis (2015) (0)
- EFFECT OF POSTNATAL EXPOSURE OF CIMETIDINE ON BLOOD TESTOSTERONE LEVEL AND HEPATIC MICROSOMAL TESTOSTERONE HYDROXYLATION ACTIVITY IN THE RAT (1984) (0)
- Novel mechanism of CAR-mediated CYP2B6 induction (2004) (0)
- Nuclear translocation of CAR is dependent on ubiquitination and proteasome‐mediated degradation of CAR cytoplasmic retention protein (CCRP) (2006) (0)
- Nuclear xenobiotic receptor PXR locks co-repressor SMRT onto the CYP24A1 promoter to attenuate vitamin D 3 activation (2008) (0)
- Preparation of Rough and Smooth Microsomes (2003) (0)
- Bioactivation of aflatoxin G1 and inhibition of affatoxin B1 toxicity in yeast cells expressing mouse CYP2A enzymes (1995) (0)
- Crystal structure of a hemagglutinin component (HA1) from type C Clostridium botulinum (2004) (0)
- Nuclear Receptor PXR; a Novel Glucose Sensor That Regulates Hepatic Gluconeogenesis (2015) (0)
- THE SULFOTRANSFERASE DOMAIN OF HUMAN HAPARIN SULFATE N-DEACETYLASE/N-SULFOTRANSFERASE (1999) (0)
- The K+ Channel KCNK1: CAR‐mediated Gene Regulation of Male‐specific Induction by PB and Hepatic Hypertrophy (2011) (0)
- Title : Phenobarbital and insulin reciprocate activation of the nuclear receptor CAR through the insulin receptor (2016) (0)
- Mouse Liver Testosterone 15 wHydroxylase ( Cytochrome P-450 & (2001) (0)
- Alteration of the substrate specificity of mouse 2A P450s by a mutation of residue-209: steroid-binding site and orientation (1992) (0)
- ESTROGEN SULFOTRANSFERASE WITH INACTIVE COFACTOR PAP AND VANADATE (1999) (0)
- Nuclear Receptors CAR, ERα and RORα Communicate via Phosphorylation to Differentially Regulate the SULT1E1 Gene Expression in Diabetic and Nondiabetic Human Livers (2020) (0)
- Turnover of enzyme proteins in microsomal membrane. (1973) (0)
- ESTROGEN SULFOTRANSFERASE WITH BOUND INACTIVE COFACTOR PAP AND 17-BETA ESTRADIOL (1998) (0)
- The human sulfotransferase SULT1A1 gene is regulated in a synergistic manner by GA binding protein and Sp1 (2004) (0)
- Crystal Structure of human 3-O-Sulfotransferase-3 with bound PAP (2004) (0)
- Nuclear receptor CAR-mediated signals responsible for hepatocellular carcinoma (2008) (0)
- Study on Electrochemical Anticorrosive Action of Pigments (1956) (0)
- The constitutive androstane receptor mediates phenytoin induction of cyp2c37 (2006) (0)
- Epidermal Growth Factor Receptor: The Phenobarbital Receptor that Elicits CAR Activation Signal for P450 Induction (2014) (0)
- ESTROGEN SULFOTRANSFERASE WITH PAP (1998) (0)
- Serum and glucocorticoid-regulated kinase 2 determines drug-activated PXR to induce gluconeogenesis in human liver cells (2013) (0)
- EVIDENCE FOR TRANSCRIPTIONAL CONTROL OF CYTOCHROME PI-450 INDUCTION BY USE OF A CLONED DNA SEQUENCE* (2001) (0)
- Azine derivative, process for its preparation, containing nematic liquid crystal composition and liquid crystal display device containing this (1997) (0)
- Structural analysis of chondroitin polymerase from Escherichia coli K4 (2011) (0)
- CRYSTAL STRUCTURE OF THE HUMAN HYDROXYSTEROID SULFOTRANSFERASE IN THE PRESENCE OF PAP (2000) (0)
- Regulation of gene expression by CAR: an update (2015) (0)
- Crystal structure of heparan sulfate 3-O-sulfotransferase isoform 1 in the presence of PAP (2004) (0)
- p38 MAPK signaling determines CAR‐mediated activation of the CYP2B genes by xenobiotics (2012) (0)
- HUMAN SULT1A3 WITH SULFATE BOUND (1999) (0)
- DRUG INDUCTION OF P450 GENES: HISTORY, MECHANISM, AND IMPLICATION (2001) (0)
- Characterization of a cloned dna sequence associated with the murine ah locus and a 3-methylcholanthrene-induced form of cytochrome p450. Abstr. (1981) (0)
- Crystal Structure of human cholesterol sulfotransferase (SULT2B1b) in the presence of PAP and pregnenolone (2003) (0)
- human beta 1,3-glucuronyltransferase I (GlcAT-I) in complex with UDP and GAL-GAL(6-SO4)-XYL(2-PO4)-O-SER (2008) (0)
- Nuclear receptor CAR-ERα signaling regulates the estrogen sulfotransferase gene in the liver (2020) (0)
- Estrogen receptor α phosphorylated at Ser216 confers inflammatory function to mouse microglia (2020) (0)
- CRYSTAL STRUCTURE OF HUMAN ESTROGEN SULFOTRANSFERASE V269E MUTANT IN THE PRESENCE OF PAPS (2002) (0)
- Gene regulation of human SULT1A sulfotransferases (2003) (0)
- RXRα Phosphorylation at Threonine 167 Coordinates Energy Metabolism in Mice (2017) (0)
- Nuclear Pregnane X Receptor Transduces Glucose Signal to Suppress Estrogen Sulfotransferase Gene in Human Liver Cells (2020) (0)
- Crystal structure of mouse alpha-1,4-N-acetylhexosaminyltransferase (EXTL2) with UDP and GlcUAb(1-3)Galb(1-O)-naphthalenelmethanol an acceptor substrate analog (2003) (0)
- Crystal structure of mouse alpha-1,4-N-acetylhexosaminyltransferase (EXTL2) (2003) (0)
- Structural Biology of Sulfotransferase (2000) (0)
- The Peripheral Benzodiazepine Receptor Ligand PK 11195 is a Novel Antagonist of Human Constitutive Androstane Receptor (2008) (0)
- Ser815 Phosphorylation stabilizes the androgen receptor homodimer and stimulates ER-stress induced cell death. (2022) (0)
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What Schools Are Affiliated With Masahiko Negishi?
Masahiko Negishi is affiliated with the following schools: