Masahiro Hirama

Masahiro Hirama's AcademicInfluence.com Rankings

Masahiro Hirama

Chemistry

#4877

World Rank

#5971

Historical Rank

Organic Chemistry

#809

World Rank

#909

Historical Rank

chemistry Degrees

Download Badge

Chemistry

Masahiro Hirama's Degrees

PhD Chemistry Kyoto University
Masters Chemistry Kyoto University
Bachelors Chemistry Kyoto University

Why Is Masahiro Hirama Influential?

(Suggest an Edit or Addition)

(See a Problem?)

Masahiro Hirama's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Total Synthesis of Ciguatoxin CTX3C (2001) (179)
ASYMMETRIC MICHAEL ADDITION OF MALONATE ANIONS TO PROCHIRAL ACCEPTORS CATALYZED BY L-PROLINE RUBIDIUM SALT (1996) (174)
Detailed LC-MS/MS analysis of ciguatoxins revealing distinct regional and species characteristics in fish and causative alga from the Pacific. (2011) (142)
Total synthesis of 6-deoxyerythronolide B (1981) (141)
A Catalytic Enantioselective Michael Addition of a Simple Malonate to Prochiral α,β‐Unsaturated Ketoses and Aldehydes (1993) (126)
First toxin profile of ciguateric fish in Madeira Arquipelago (Europe). (2010) (115)
The Absolute Configuration of Ciguatoxin (1997) (107)
Ciguatera incidence and fish toxicity in Okinawa, Japan. (2010) (93)
Inhibition of brevetoxin binding to the voltage-gated sodium channel by gambierol and gambieric acid-A. (2003) (91)
A chiral total synthesis of compactin (1982) (90)
The 10-membered ring analogs of neocarzinostatin chromophore: design, synthesis and mode of decomposition (1989) (87)
Practical total synthesis of ciguatoxin CTX3C by improved protective group strategy. (2002) (87)
First- and second-generation total synthesis of ciguatoxin CTX3C. (2004) (86)
Asymmetric Michael addition of nitroalkanes to prochiral acceptors catalyzed by proline rubidium salts (1997) (81)
Total synthesis of merrilactone A. (2003) (79)
Asymmetric Baylis-Hillman reactions using chiral 2,3-disubstituted 1,4-diazabicyclo[2.2.2]octanes catalysts under high pressure conditions (1995) (77)
Synthesis-based approach toward direct sandwich immunoassay for ciguatoxin CTX3C. (2003) (75)
CATALYTIC ASYMMETRIC MICHAEL ADDITION OF NITROALKANE TO ENONE AND ENAL (1994) (73)
A concise synthesis of the pentacyclic framework of cortistatins. (2008) (72)
Total synthesis of ciguatoxin and 51-hydroxyCTX3C. (2006) (68)
Carbamate-mediated functionalization of unsaturated alcohols. 3. Intramolecular Michael addition of O-carbamates to .alpha.,.beta.-unsaturated esters. A new diastereoselective amination in an acyclic system (1985) (65)
Highly Enantioselective Dihydroxylation of Trans-Disubstituted and Monosubstituted Olefins (1989) (65)
Synthetic Study of Kedarcidin Chromophore: Revised Structure (1997) (65)
Synthesis and Characterization of Nine-Membered Cyclic Enediynes, Models of the C-1027 and Kedarcidin Chromophores: Equilibration with a p-Benzyne Biradical and Kinetic Stabilization (1995) (63)
Evolution of a practical total synthesis of ciguatoxin CTX3C. (2004) (61)
Total synthesis and bioactivity of an unnatural enantiomer of merrilactone a: development of an enantioselective desymmetrization strategy. (2007) (61)
Palladium catalyzed stereospecific cyclization of hydroxy epoxides. Stereocontrolled synthesis of cis- and trans-2-alkenyl-3-hydroxytetrahydropyrans (1990) (60)
Total synthesis of cortistatins A and J. (2011) (59)
Total Synthesis of Limonin. (2015) (58)
Asymmetric total synthesis of (-)-merrilactone A: use of a bulky protecting group as long-range stereocontrolling element. (2006) (56)
EFFICIENT ROUTE TO THE NINE-MEMBERED CYCLIC DIYNE SYSTEM : TUNING OF THE EXTREMELY FACILE COPE REARRANGEMENT OF 1,5-DIYNE (1994) (55)
Total syntheses of complanadines A and B. (2013) (54)
Total synthesis of TMC-95A. (2003) (53)
A Direct and Efficient α-Selective Glycosylation Protocol for the Kedarcidin Sugar, L-Mycarose: AgPF6 as a Remarkable Activator of 2-Deoxythioglycosides. (2001) (52)
Synthesis and DNA cleaving abilities of functional neocarzinostatin chromophore analogs. Base discrimination by a simple alcohol (1991) (52)
Ortho-Vinylation and Ortho-Alkenylation of Phenols (1995) (50)
Synthesis of a hybrid molecule containing neocarzinostatin chromophore analogue and minor groove binder (1993) (50)
Stereospecific total synthesis of dl-pentalenolactone (1978) (49)
A formal total synthesis of (+)-pinnatoxin A. (2004) (48)
Synthetic study of kedarcidin chromophore: atropselective construction of the ansamacrolide (1999) (48)
Two diverse modes of aromatization of a new 10-membered ring analogue of neocarzinostatin chromophore (1990) (47)
Solution structures of C-1027 apoprotein and its complex with the aromatized chromophore. (2001) (46)
Stereodivergent total synthesis of N-acetylacosamone and N-benzoylristosamine (1987) (46)
Convergent synthesis of the trans-fused 6-n-6-6 (n = 7–10) tetracyclic ether system based on a ring-closing metathesis reaction (1998) (46)
Production of monoclonal antibodies for sandwich immunoassay detection of ciguatoxin 51-hydroxyCTX3C. (2006) (46)
Convergent synthesis of the ABCDE ring system of ciguatoxin CTX3C (2002) (45)
Expeditious tandem-metathesis route to the AB-ring fragment of ciguatoxin (1999) (45)
Total synthesis of ciguatoxin CTX3C: a venture into the problems of ciguatera seafood poisoning. (2005) (45)
Enantioselective synthesis of the AB ring fragment of gambiertoxin 4B. Implication for the absolute configuration of gambiertoxin 4B and ciguatoxin (1991) (44)
Enyne[3]cumulene. Synthesis and mode of aromatization (1991) (43)
A quantitative and comparative study of the effects of a synthetic ciguatoxin CTX3C on the kinetic properties of voltage‐dependent sodium channels (2004) (43)
A concise route to two distinct E-ring structures of ciguatoxins (2007) (41)
Synthesis and absolute stereochemistry of the aminosugar moiety of antibiotic C-1027 chromophore (1993) (40)
Synthesis of chiral 2,3-disubstituted 1,4-diazabicyclo [2.2.2] octane. New ligand for the osmium-catalyzed asymmetric dihydroxylation of olefins (1992) (40)
CARBAMATE MEDIATED FUNCTIONALIZATION OF UNSATURATED ALCOHOLS. II. REGIO‐ AND STEREO‐SELECTIVE SYNTHESIS OF 1,3‐SYN AND 1,2‐ANTI AMINO ALCOHOL DERIVATIVES VIA IODOCARBAMATION (1985) (39)
Synthetic study of ciguatoxin. Absolute configuration of the C2 hydroxy group (1997) (39)
A new stereoselective synthesis of ciguatoxin right wing fragments. (2004) (39)
Efficient construction of the kedarcidin chromophore ansamacrolide. (2005) (39)
Concise Total Synthesis of (±)‐Lycodine (2010) (39)
Chemistry and antimicrobial activity of caryoynencins analogs. (1995) (39)
Total synthesis of dl-pentalenolactone (1979) (38)
Convergent synthesis of the HIJKLM ring fragment of ciguatoxin CTX3C (2002) (38)
Carbamate mediated 1,3-asymmetric induction. A stereoselective synthesis of acyclic 1,3-diol systems (1982) (38)
Synthesis and binding of simple neocarzinostatin chromophore analogues to the apoprotein (1994) (38)
Production of monoclonal antibodies for sandwich immunoassay detection of Pacific ciguatoxins. (2010) (38)
A simple synthesis of L-.gamma.-carboxyglutamate and derivatives thereof (1979) (37)
Photochemical Cycloaromatization of Non-Benzenoid Enediynes. (1999) (37)
SbF5-Promoted Addition of Aldehydes to Alkynes (1995) (37)
Synthetic Ciguatoxins Selectively Activate Nav1.8-derived Chimeric Sodium Channels Expressed in HEK293 Cells* (2009) (36)
Use of the E-vinyloxyborane derived from S-phenyl propanethioate for stereospecific aldol-type condensation. A simplified synthesis of the prelog-djerassi lactonic acid (1980) (35)
Convergent synthesis of the EFGH ring fragment of ciguatoxin CTX3C (2001) (35)
Total Synthesis of Ciguatoxin CTX3C, a Causative Toxin of Ciguatera Seafood Poisoning (2004) (35)
Effect of ciguatoxin 3C on voltage-gated Na+ and K+ currents in mouse taste cells. (2006) (34)
Concise synthesis of ciguatoxin ABC-ring fragments and surface plasmon resonance study of the interaction of their BSA conjugates with monoclonal antibodies. (2001) (33)
Asymmetric dihydroxylation of alkenes with osmium tetroxide: chiral N,N′-dialkyl-2,2′-bipyrrolidine complex (1989) (33)
Two convergent routes to the left-wing fragment of ciguatoxin CTX3C using O,S-acetals as key intermediates. (2006) (32)
Enantiospecific syntheses of trifunctional (R)-3-hydroxy esters by baker's yeast reduction (1983) (32)
Stereocontrolled synthesis of the northern part of potent proteasome inhibitor TMC-95A. (2001) (32)
Stereoselective synthesis of β-hydroxy-α-methylcarboxylic acid thiol esters via vinyloxyboranes (1979) (31)
Benzannelation alters the rate limiting step in enediyne cycloaromatization (1999) (31)
Novel Assembly of Cyclic Ethers by Coupling α-Chlorosulfides and Alcohols (2002) (31)
Stereocontrolled synthesis of the ABCDE ring moiety of ciguatoxin CTX3C (2004) (30)
Carbometalation of ketone enolates with 1-alkynes: an alkylidenation reaction of silyl enol ethers promoted by stannic chloride-tri-n-butylamine (SnCl4-Bu3N) reagent (1993) (30)
Highly Sensitive and Practical Fluorescent Sandwich ELISA for Ciguatoxins. (2018) (30)
Rhodium-catalyzed cross coupling of unactivated allenes and 1-alkynes (1994) (30)
Synthesis of disodium prephenate and disodium epiprephenate. Stereochemistry of prephenic acid and an observation on the base-catalyzed rearrangement of prephenic acid to p-hydroxyphenyllactic acid (1979) (29)
Stereoselective 6-exo radical cyclization using cis-vinyl sulfoxide: practical total synthesis of CTX3C. (2011) (29)
Chiral recognition of an anionic tetrahelicene by native cyclodextrins. Enantioselectivity dominated by location of a hydrophilic group of the guest in a cyclodextrin cavity (1999) (29)
Efficient and stereoselective installation of isoquinoline: formal total synthesis of cortistatin A (2009) (28)
Stereoselective Synthesis of (+)-Swainsonine and (-)-8,8a-Di-epi-swainsonine (1995) (28)
TMC-95A, a reversible proteasome inhibitor, induces neurite outgrowth in PC12 cells. (2004) (28)
Friedel–Crafts β‐Silylvinylations (1997) (28)
Absolute configuration of C-1027 chromophore (1996) (27)
Enantioselective synthesis of the medium ring ethers, tetrahydrooxepin, oxocane and hexahydrooxonin, of ciguatoxin. Extensive ring-expansion and chemoenzymatic desymmetrization strategy (1999) (27)
Conjugate addition of internal nucleophile to chiral vinyl sulfoxides with stereogenic center at the allylic carbon. “intramolecular” double asymmetric induction (1988) (27)
Practical entry into the HIJKLM ring segment of ciguatoxin CTX3C (2001) (27)
Development of a monoclonal antibody against the left wing of ciguatoxin CTX1B: thiol strategy and detection using a sandwich ELISA. (2012) (26)
Synthesis and Reactions of Monosilylated 1,3,5-Hexatriyne and 1,3,5,7-Octatetrayne. Total Synthesis of Caryoynencins. (1994) (26)
ALLYLGALLATION REACTION OF CARBON-CARBON TRIPLE BONDS WITH ALLYLSILANES AND GACL3 (1997) (26)
Benzannelation Effect on Enediyne Cycloaromatization: An ab Initio Molecular Orbital Study (1999) (26)
Synthesis and preliminary biological evaluation of truncated zoanthenol analogues. (2004) (25)
Ortho-Vinylation Reaction of Phenols with Ethyne. (1998) (25)
Synthesis of the fully functionalized ABCDE ring moiety of ciguatoxin. (2004) (25)
Construction of the benzylic quaternary carbon center of zoanthenol by intramolecular Mizoroki-Heck reaction of enone. (2002) (25)
Divergent synthesis of the tetracyclic ethers of 6-X-7-6 ring systems (2003) (25)
The source of the oxygen atom in the alpha-hydroxyglycine intermediate of the peptidylglycine alpha-amidating reaction. (1992) (25)
Untitled Document (2001) (24)
New acyclic apporach to 3-amino-2,3,6-trideoxy-L-hexoses: a stereocontrolled synthesis of N-benzoyl L-daunosamine (1986) (24)
Formal total synthesis of neocarzinostatin chromophore. (2006) (24)
Total synthesis of the maduropeptin chromophore aglycon. (2007) (24)
Design and synthesis of a trans-fused polycyclic ether skeleton as an α-helix mimetic scaffold (2005) (23)
Stereocontrolled construction of the hexahydrobenzofuran subunit of the avermectins and the milbemycins: the aldol strategy (1988) (23)
Biomimetic total synthesis of cyanosporaside aglycons from a single enediyne precursor through site-selective p-benzyne hydrochlorination. (2014) (23)
Oxidative triggering for aromatization of the neocarzinostatin chromophore (1990) (23)
Total synthesis of a protected aglycon of the kedarcidin chromophore. (2009) (23)
Synthesis of the C-1027 chromophore framework through atropselective macrolactonization. (2004) (23)
Investigation of the total synthesis of N1999-A2: implication of stereochemistry. (2001) (23)
Synthesis of Exo-enynes by Ruthenium-Catalyzed Cross Coupling Reaction of Hydroxy Allenes and 1-Alkynes (1995) (23)
Convergent synthesis of the ABCDE ring framework of ciguatoxin (1999) (23)
Regioselective conjugate addition of sulfonylallyl carbanions to α, β-unsaturated ketones (1981) (23)
Preparation of anti-ciguatoxin monoclonal antibodies using synthetic haptens: sandwich ELISA detection of ciguatoxins. (2014) (22)
Convergent Strategy for Synthesizing Polycyclic Ether Marine Toxins: Synthesis of the ABCDE Ring Fragment of Ciguatoxin CTX3C (2001) (22)
ortho-Vinylation reaction of anilines (1998) (22)
Simple strategy for the synthesis of the avermectin-milbemycin family. Total synthesis of milbemycin .alpha.1 (1991) (22)
Total synthesis of aspercyclides A and B via intramolecular oxidative diaryl ether formation. (2012) (22)
A concise route to the right wing of ciguatoxin (2003) (22)
Convergent Synthesis of a Trans-fused 6-7-6 Tricyclic Ether System Based on a Ring-closing Metathesis Reaction (1997) (22)
Spin trapping of 13C-labeled p-benzynes generated by Masamune-Bergman cyclization of bicyclic nine-membered enediynes. (2004) (22)
A comparative study of the effect of ciguatoxins on voltage-dependent Na+ and K+ channels in cerebellar neurons. (2011) (22)
Synthesis of optically active macrocycles consisting of helical chiral unit 1,12-dimethylbenzo[c]phenanthrene-5,8-dicarboxylate as a novel chiral building block (1996) (21)
New convenient, enantiospecific synthesis of (S,S)- and (R,R)-2,2′-bipyrrolidine derivatives (1995) (21)
Remarkable kinetic solvent isotope effect on the cycloaromatization of C-1027 chromophore, a 9-membered enediyne, and the thermochemistry (1994) (21)
The first total synthesis of N1999-A2: absolute stereochemistry and stereochemical implications into DNA cleavage. (2001) (21)
Solution structure of the antitumour antibiotic neocarzinostatin, a chromophore–protein complex (1993) (21)
Reinvestigation of the Diastereoselectivity of Kinetic Aldol Condensation of Cyclohexanone Lithium Enolate with Benzaldehyde (1988) (21)
Enantiospecific synthesis of the spiroacetal unit of avermectin b1a (1986) (20)
Phage-display selection of antibodies to the left end of CTX3C using synthetic fragments. (2004) (20)
Paramagnetic Enediyne Antibiotic C-1027: Spin Identification and Characterization of Radical Species (2000) (20)
Enantio-face control by molecular sieves in the asymmetric Diels-Alder reaction (2000) (20)
EFFICIENT SYNTHESIS OF A CARBOCYCLIC CORE MOIETY WITH THE STEREOCHEMISTRY OF THE C-1027 CHROMOPHORE (1996) (20)
The absolute configuration and total synthesis of korormicin (1999) (20)
A simple and efficient synthesis of the naphthoate moiety of neocarzinostatin chromophore (1992) (19)
CHIRAL RECOGNITION OF TETRAHELICENE DICARBOXYLIC ACID BY LINEAR DEXTRINS (1997) (19)
Design and synthesis of a conformationally restricted analogue of the EFGH-ring system of ciguatoxin (2009) (19)
Direct Formation of Reactive Alkynyltrichlorotins from 1-Alkynes, SnCl4, and Bu3N. A Mild Alkynylation Reagent of Aldehydes, Acetals, and Enones (1992) (19)
A very short route to the functionalized A-ring moiety of ciguatoxin (2000) (19)
Addressing the analytical challenges for the detection of ciguatoxins using an electrochemical biosensor. (2020) (19)
Total synthesis and structure revision of the (-)-maduropeptin chromophore. (2009) (19)
CONVERGENT SYNTHESIS OF THE IJKLM RING FRAGMENT OF CIGUATOXIN CTX3C (1999) (19)
Convenient synthesis of (S)-citronellol of high optical purity (1985) (19)
Synthetic study of the kedarcidin chromophore: Efficient construction of the aryl alkyl ether linkage (1998) (19)
Synthesis and evaluation of α-helix mimetics based on a trans-fused polycyclic ether: sequence-selective binding to aspartate pairs in α-helical peptides (2006) (19)
Oxidation of Benzyl Ether to Benzoate by Ozone (1983) (18)
A new entry into the synthesis of the strychnos indole alkaloids containing 19,20-double bond via the thio-claiser rearrangement (1982) (18)
Total synthesis of (+)-monacolin K (mevinolin) (1983) (18)
Reversal of diastereofacial selectivity in the intramolecular michael addition of -α-carbamoyloxy-α,β-unsaturated esters. Synthesis of N-benzoyl-D,L-daunosamine (1985) (18)
Total synthesis of the C-1027 chromophore core: extremely facile enediyne formation through Sml2-mediated 1,2-elimination. (2008) (18)
Differential effects of ciguatoxin and maitotoxin in primary cultures of cortical neurons. (2014) (18)
Asymmetric dihydroxylation of chiral olefins. High control of diastereofacial selection (1993) (18)
Synthetic Study of Pinnatoxin A: Intramolecular Diels-Alder Approach to the AG-ring (1999) (18)
Designed Hapten Aimed at Anti-ciguatoxin Monoclonal Antibody: Synthesis, Immunization and Discrimination of the C2 Configuration (1999) (18)
Synthesis of the bicyclo[7.3.0]dodecatrienediyne core of the C-1027 chromophore. (2004) (17)
Synthesis of the C11-C28 subunit of the avermectins (1988) (17)
Total synthesis of avermectin B1a revisited (2015) (17)
Synthesis of Chiral 2,2′-Bipyrrolidine Derivatives (1992) (17)
Enantio-Controlled Synthesis of the AB Ring Moiety of Ciguatoxin (1995) (17)
Antitumor enediyne chromoprotein C-1027: mechanistic investigation of the chromophore-mediated self-decomposition pathway. (2006) (17)
Recognition of Helicity by Native Cyclodextrins.Highly Enantioselective Complexation of Tetrahelicene Dicarboxylic Acid with β-Cyclodextrin (1998) (17)
Synthetic Study of Pinnatoxin A: Intramolecular Alkylation Approach to the G-ring (1999) (17)
Concise Synthesis of 3-O-(2-O-α-d-Glucopyranosyl-6-O-acyl-α-d-glucopyranosyl)-1,2-di-O-acyl-sn-glycerols (2000) (17)
Proton NMR studies on the chromophore binding structure in neocarzinostatin complex (1991) (17)
Use of polystyrene-supported DBU in the synthesis and alpha-selective glycosylation study of the unstable Schmidt donor of L-kedarosamine. (2004) (17)
A concise route to the C2-symmetric tricyclic skeleton of ryanodine (2009) (16)
Synthesis and chemistry of chromoprotein antitumor antibiotics: Nine-membered enediynes are equilibrated with p-benzyne type biradicals (1997) (16)
Convenient Route to Both Enantiomerically Pure Forms of trans-4,5-Dihydroxy-2-cyclopenten-1-one: Efficient Synthesis of the Neocarzinostatin Chromophore Core (2001) (16)
Synthetic Study of Zoanthamine Alkaloids: The C-ring Model Possessing Three Consecutive Quaternary Carbons (1999) (16)
Synthesis of the entire carbon framework of the kedarcidin chromophore aglycon. (2007) (16)
Convergent synthesis of the ABC-ring moiety of zoanthenol: Intramolecular Mizoroki-Heck reaction (2001) (16)
Total synthesis of disodium prephenate. (1977) (16)
Neocarzinostatin Complex: Chromophore Analogs, Binding Structure and Stabilization Mechanism. (1994) (15)
Highly Stereocontrolled Synthesis of the ABCD Ring Fragment of Ciguatoxin CTX3C (2001) (15)
Extensive Ring-Expansion Strategy for the Enantioselective Synthesis of the Medium Ring Ethers, Oxepene, Oxocane, and Oxonene, of Ciguatoxin (1996) (15)
Ten-membered neocarzinostatin chromophore analogs leading to σ,σ-biradical via a cumulene intermediate (1994) (15)
Stereoselective synthesis of zoanthenol ABC-ring by radical strategy (2013) (15)
Synthetic studies toward C-1027 chromophore: construction of a highly unsaturated macrocycle (2001) (15)
Critical Contribution of Aromatic Rings to Specific Recognition of Polyether Rings (2008) (15)
Convenient route to derivatives of the 2-deoxysugar subunits of the kedarcidin chromophore: L-mycarose and L-kedarosamine (1999) (15)
Synthetic Study of Pinnatoxin A: Stereoselective Synthesis of the BCD-ring Unit, a Novel 6,5,6-Bis-spiroketal System (1998) (15)
Alkynyldichlorogalliums are Unstable in Hydrocarbon Solvents Dimerization of Alkynyldichlorogalliums via Carbogallation (1995) (14)
Synthesis and Cycloaromatization of a Neocarzinostatin Chromophore Analogue Equipped with an Intramolecular Nucleophile (1991) (14)
Enantioselective synthesis of the fully functionalized ABC ring of zoanthenol. (2008) (14)
Chronic ciguatoxin treatment induces synaptic scaling through voltage gated sodium channels in cortical neurons. (2015) (14)
Critical importance of the nine-membered F ring of ciguatoxin for potent bioactivity: total synthesis and biological evaluation of F-ring-modified analogues. (2008) (14)
Stereocontrolled synthesis of the HIJ ring system ofciguatoxin (1997) (14)
Rapid detection of ciguatoxins in Gambierdiscus and Fukuyoa with immunosensing tools. (2020) (13)
Asymmetric Induction in the Intramolecular Conjugate Addition of g- or d-Carbamoyloxy-a,b-unsaturated Esters. A New Method for Diastereoselective Amination and Divergent Syntheases of 3-Amino-2,3,6-Trideoxyhexoses (1989) (13)
Palladium-catalyzed coupling of alkenyl iodides with ethynyl oxiranes: Synthesis of epoxy enediyne core intermediates related to neocarzinostatin chromophore (1996) (13)
Synthesis of the LMN-ring fragment of the Caribbean ciguatoxin C-CTX-1 (2007) (13)
Convergent synthesis of the ABCDE-ring fragment of the Caribbean ciguatoxin C-CTX-1 (2007) (13)
How Protein Recognizes Ladder-like Polycyclic Ethers (2008) (13)
Convergent assembly of polycyclic ethers via acyl radical addition to unactivated enol ether. (2006) (13)
Total Synthesis and Absolute Configuration of (-)-Sedacryptine (1996) (12)
Rationally Designed Synthetic Haptens to Generate Anti-Ciguatoxin Monoclonal Antibodies, and Development of a Practical Sandwich ELISA to Detect Ciguatoxins (2019) (12)
Use of monoclonal antibodies as an effective strategy for treatment of ciguatera poisoning. (2009) (12)
A new synthesis of key intermediates for the assembly of polycyclic ethers: Yb(OTf)3-promoted formation of O,S-acetals from α-fluorosulfides and alcohols (2004) (12)
Modeling study of the structure of the macromolecular antitumor antibiotic neocarzinostatin. Origin of the stabilization of the chromophore. (1991) (12)
2,6-Divinylation of phenols with ethyne (1997) (12)
Synthetic ciguatoxin CTX 3C induces a rapid imbalance in neuronal excitability. (2015) (12)
Convergent approach to the maduropeptin chromophore: aryl ether formation of (R)-3-aryl-3-hydroxypropanamide and cyclization of macrolactam (2004) (11)
Characterization of 11-dehydro-thromboxane B2 recombinant antibody obtained by phage display technology. (2003) (11)
Structural factors governing stereoselective heck reaction for the construction of the oxindole portion of TMC-95A (2006) (11)
New Synthetic Route to the Highly Strained Cores of C-1027 and Neocarzinostatin Chromophores (1998) (11)
Stereoselective synthesis of the left wing of Caribbean ciguatoxin (2011) (11)
Sensitized photooxidation of gurjunene: cleavages of the cyclopropane ring (1972) (11)
A SIMPLE DESYMMETRIZATION APPROACH TO THE SPIROXIN FRAMEWORK (2008) (10)
Stereoselective Synthesis of the LM Ring Moiety of Ciguatoxin : Reagent Control of Asymmetric Dihydroxylation (1997) (10)
Synthetic Study of Kedarcidin Chromophore: Revised Structure. (1998) (10)
Rational design of a supra C-1027: kinetically stabilized analogue of the antitumor enediyne chromoprotein. (2004) (9)
Synthetic Study of C - 1027 Chromophore: Enantioselective Synthesis of β - Tyrosine Moiety and Effective Aryl Ether Formation (1999) (9)
Design, production, and characterization of recombinant neocarzinostatin apoprotein in Escherichia coli. (2002) (9)
Diastereofacial selectivity in the intramolecular conjugate addition of a nitrogen nucleophile; stereocontrolled piperidine synthesis (1987) (9)
A convergent total synthesis of the kedarcidin chromophore: 20-years in the making (2019) (9)
Desilylation Reactions of Poly[(t-butyldimethylsilyloxy)phenylacetylene]s (1992) (9)
Competent Route to Unsymmetric Dimer Architectures: Total Syntheses of (-)-Lycodine and (-)-Complanadines A and B, and Evaluation of Their Neurite Outgrowth Activities. (2017) (9)
Evidence for Spontaneous Cycloaromatization of Nine-Membered Monocyclic Enediyne. (1998) (9)
A very concise and stereoselective synthesis of 3-substituted cis-hex-3-ene-1,5-diyne and corresponding epoxydiyne. (2001) (9)
Secure route to the epoxybicyclo[7.3.0]dodecadienediyne core of the kedarcidin chromophore. (2008) (9)
Synthetic Study of Kedarcidin Chromophore: Advanced Models and Their Chemical Behavior (1997) (9)
Chemical reactions of o-tropoquinone and its derivatives. (1979) (8)
Synthesis of the AB Ring Fragment of Ciguatoxin: Ligand Controlled Regioselective Addition of Osmium Tetroxide to Double Bonds (1992) (8)
Practical route to the left wing of CTX1B and total syntheses of CTX1B and 54-deoxyCTX1B. (2015) (8)
Isolation, characterization and molecular structure of o-tropoquinone (1978) (8)
Synthesis of trans-fused tetrahydrooxepins: stereoselective allylation of sulfur or fluoro-substituted tetrahydrooxepins. (2008) (8)
The first F-ring modified ciguatoxin analogue showing significant toxicity. (2010) (8)
α-Alkenylation of Ketones with 1-Alkynes (1995) (8)
DIRECT OBSERVATION OF ESR SPECTRA OF BICYCLIC NINE-MEMBERED ENEDIYNES AT AMBIENT TEMPERATURE ‡ (2006) (8)
Glycoglycerolipid from the Membranes of Acholeplasma laidlawii Binds to Human Immunodeficiency Virus-1 (HIV-1) and Accelerates Its Entry into Cells (2004) (8)
On the conformation of Phe78 of a chromoprotein antibiotic, neocarzinostatin. (1995) (8)
Trifunctional chiral synthons via stereocontrolled yeast reduction. Preparation of chiral pentane-1,3,5-triol derivatives. (1986) (8)
The Absolute Configuration of Ciguatoxin. (1998) (8)
1,2,3-BENZOTROPOQUINONE (1979) (8)
A Novel Route to 1,8-Dihydroxy-naphthalene-derived Natural Products. Synthesis of (±)-CJ-12,372 (2003) (8)
Transcriptomic Analysis of Ciguatoxin-Induced Changes in Gene Expression in Primary Cultures of Mice Cortical Neurons (2018) (8)
Expeditious Synthesis of Enantiomerically Pure trans-4,5-Dihydroxy-2-cyclopenten-1-one (1995) (7)
A study on mechanisms of toxic actions of ciguatoxins: existence of functional relationship between CTX3C and charged residues of voltage sensors in Nav1.4 sodium channel (2011) (7)
Internal amide-triggered cycloaromatization of maduropeptin-like nine-membered enediyne. (2008) (7)
Synthetic Study of C-1027 Chromophore. Highly Stereoselective Glycosylation. (2010) (7)
STEREOSELECTIVE HYDROGENATION OF TETRASUBSTITUTED ENONES (2004) (7)
Design and Synthesis of Neocarzinostatin Analogues (1991) (7)
On the origin of photo-lability of neocarzinostatin chromophore (1993) (7)
Synthesis of 13C-labelled, bicyclic mimetics of natural enediynes. (2002) (6)
ESR studies on DNA cleavage induced by enediyne C-1027 chromophore. (2005) (6)
Binding of glycoglycerolipid derived from membranes of Acholeplasma laidlawii PG8 and synthetic analogues to lymphoid cells. (2000) (6)
Synthesis of cyclopent-2-enones through stepwise [3 + 2] cycloaddition of simple silyl enol ethers and alk-1-ynes (1993) (6)
Catalytic Asymmetric Michael Addition of Nitroalkane to Enone and Enal. (1995) (5)
Diastereoselective deoxymercuration in cyclic system. A remarkable assistance by the neighboring carbonate group (1987) (5)
Remote C–H bond functionalization of androstane C-ring: C12-amination (2013) (5)
A New Method for Diastereoselective Amination in Acyclic System and Total Synthesis of Amino Sugars (1987) (5)
Dioxetane intermediate in the sensitized photooxidation of thujopsene (1971) (5)
Diastereoselective additions of ethynyl Grignard reagent to erythrulose derivatives (2002) (5)
STEREOSELECTIVE SYNTHESIS OF CARIBBEAN CIGUATOXIN M-RING USING [2+2] PHOTOCYCLIZATION (2010) (5)
Synthesis of the fully functionalized nine-membered diyne core of the C-1027 chromophore (2004) (5)
Reactions of neocarzinostatin chromophore analogues with molecular oxygen (1994) (5)
Chemistry and Antimicrobial Activities of 3,5,7,9-Decatetrayn-2-ol and Related Compounds (1997) (5)
Copper(II)-Catalyzed O-Arylationof Tertiary Alcohols with Arylbismuth(III) Reagents: A ConvenientSystem for Aryl Transfer (2012) (5)
Nucleophilic reactions of p-tropoquinone (1976) (5)
Concise Synthesis of the Tetracyclic Framework of Azadiradione : Tandem Radical Cyclization Route (2013) (5)
Spin-trapping Study of DNA Cleavage Induced by Enediyne C-1027 Chromophore (2002) (5)
Molecular recognition in neocarzinostatin complex: how does the apoprotein bind specifically and stabilize the chromophore? (1994) (4)
Remarkable Selectivity in Derivatization and Protection of Hydroxy Groups of 51-hydroxyCTX3C: Chemoselective Synthesis of Biotin-conjugated Ciguatoxin Derivatives (2009) (4)
Conversion of gurjunene to 10-epizierone:Stereochemistry of zierone (1972) (4)
Syntheses of cyclohepta-3,6-diene-1,2,5-trione, p-tropoquinone (1975) (4)
Recent Advances in the Synthetic Studies of Nine-membered Enediyne Antitumor Antibiotics (2010) (4)
A smartphone-controlled amperometric immunosensor for the detection of Pacific ciguatoxins in fish (2021) (4)
First-and second-generation total synthesis of ciguatoxin CTX 3 C (2004) (4)
The First Total Synthesis of Gravicycle (2012) (4)
Synthesis of the bicyclo[7.3.0]dodecadiyne core of the maduropeptin chromophore. (2008) (4)
Stereoselective Synthesis of Functionalized (Z)-Keto-enyne and its Epoxide (2000) (4)
Friedel-Crafts--Silylvinylierungen (1997) (4)
Total Synthesis of 9-Membered Enediyne Antibiotic N1999-A2 (2004) (4)
Synthesis of marine natural products containing polycyclic ethers (2002) (4)
SYNTHETIC STUDY OF NEOCARZINOSTATIN CHROMOPHORE : STEREOSELECTIVE SYNTHESIS OF N-METHYLFUCOSAMINE AND ITS ALPHA -GLYCOSIDE (1998) (4)
Synthesis of Deeply Colored Soluble Polyacetylenes from 1-Ethynylnaphthalene and 3,6-Dibutyl-9-ethynylphenanthrene (1992) (4)
Structural and energetic hot-spots for the interaction between a ladder-like polycyclic ether and the anti-ciguatoxin antibody 10C9Fab. (2011) (3)
Total Synthesis of Merrilactone A (2007) (3)
Total synthesis and related studies of large, strained, and bioactive natural products (2016) (3)
Additions and Corrections - Convenient Synthesis of (S)-Citronellol of High Optical Purity. (1985) (3)
Z-Selective Horner—Wadsworth—Emmons Reaction of Ethyl (Diarylphosphono)acetates Using Sodium Iodide and DBU. (2000) (3)
Synthesis and DNA-Cleaving Abilities of Functional Neocarzinostatin Chromophore Analogues. Base Discrimination by a Simple Alcohol. (1992) (3)
Synthesis and Chemistry of Neocarzinostatin Analogues (1994) (3)
Ortho-Vinylation Reaction of Phenols. (1996) (3)
Asymmetric Michael Addition of Malonate Anions to Prochiral Acceptors Catalyzed by L-Proline Rubidium Salt. (2010) (3)
A Simple Desymmetrization Approach to the Spiroxin Framework. (2009) (3)
Concise Synthesis of 3-O-(2-O-α-D-Glucopyranosyl-6-O-acyl-α-D-glucopyranosyl) -1,2-di-O-acyl-sn-glycerols. (2001) (3)
THIELE ACETYLATION OF p-TROPOQUINONE, AN ABNORMAL RING CONTRACTION (1977) (3)
A Novel Route to 1,8-Dihydroxynaphthalene-Derived Natural Products. Synthesis of (.+-.)-CJ-12,372. (2003) (2)
Synthetic Studies on Presporolide, a Putative Enediyne Precursor of Sporolides. (2018) (2)
Synthesis of (-)-Merrilactone A (2006) (2)
Practical Synthesis of theC-1027 Aminosugar Moiety (2010) (2)
Concise Synthesis of the Naphthoate Component of N1999-A2 (1999) (2)
The base catalyzed conversion of prephenate to p-hydroxyphenyllactic acid (1977) (2)
Synthesis and Characterization of Nine‐Membered Cyclic Enediynes, Models of C‐1027 and Kedarcidin Chromophore: Equilibration with a p‐ Benzyne Biradical and Kinetic Stabilization. (1995) (2)
Total Syntheses of Compactin (ML-236B) and Monacolin K (Mevinolin) (1983) (2)
Asymmetric Baylis‐Hillman Reactions Using Chiral 2,3‐Disubstituted 1,4‐ Diazabicyclo(2.2.2)octanes Catalysts under High Pressure Conditions. (1995) (2)
Asymmetric OsO4 Oxidation with 2, 2'-Bipyrrolidine Ligands (1990) (2)
Total Synthesis and Absolute Configuration of (-)-Sedacryptine. (1996) (2)
A SIMPLE SYNTHESIS OF L-Γ-CARBOXYGLUTAMATE AND DERIVATIVES THEREOF (1979) (2)
Synthetic Study of Pinnatoxin A: Intramolecular Alkylation Approach to the G-Ring. (1999) (2)
CARBAMATE-MEDIATED FUNCTIONALIZATION OF UNSATURATED ALCOHOLS. 3. INTRAMOLECULAR MICHAEL ADDITION OF O-CARBAMATES TO α,β-UNSATURATED ESTERS. A NEW DIASTEREOSELECTIVE AMINATION IN AN ACYCLIC SYSTEM (1985) (2)
Synthetic Study of Neocarzinostatin Chromophore: Stereoselective Synthesis of N-Methylfucosamine and Its α-Glycoside. (1998) (2)
Cycloaddition reaction of p-tropoquinone and its utilization to the synthesis of 1,2,5-benzotropoquinone (1978) (2)
Synthesis and Cycloaromatization of a Neocarzinostatin Chromophore Analogue (I) Equipped with an Intramolecular Nucleophile. (1992) (2)
Construction of the AG-ring unit of pinnatoxin A via intramolecular alkylation and Aza-Wittig reaction (2003) (2)
Simple Strategy for the Synthesis of the Avermectin-Milbemycin Family. Total Synthesis of Milbemycin α1. (1991) (2)
Synthesis of Ciguatoxin (CTX1B) (2006) (2)
Total Synthesis of TMC‐95A. (2003) (1)
Reversal of Diastereofacial Selectivity in the Intramolecular Michael Addition of δ-Carbamoyloxy-α,β-Unsaturated Esters. (1986) (1)
Synthetic Study of Ciguatoxin. Absolute Configuration of the C-2 Hydroxy Group. (1997) (1)
Enantioselective Synthesis of the Medium Ring Ethers, Tetrahydrooxepin, Oxocane and Hexahydrooxonin of Ciguatoxin. Extensive Ring‐Expansion and Chemoenzymatic Desymmetrization Strategy. (1999) (1)
Total Synthesis of Milbemycin α1 (1991) (1)
A Concise Route to the Right Wing of Ciguatoxin. (2003) (1)
Evolution of a Practical Total Synthesis of Ciguatoxin CTX3C (2005) (1)
Solvent-mediated Tuning of the Regioselectivity of Intramolecular Diaryl Ether Formation: Total Synthesis of (+)-Aspercyclide C (2014) (1)
Synthesis of Chiral 2,3‐Disubstituted 1,4‐Diazabicyclo(2.2.2)octane. New Ligand for the Osmium‐Catalyzed Asymmetric Dihydroxylation of Olefins. (1992) (1)
Ortho-Vinylation and Ortho-Alkenylation of Phenols. (1995) (1)
Design and Synthesis of a Conformationally Restricted Analogue of the EFGH-Ring System of Ciguatoxin. (2009) (1)
Concise Synthesis of the Naphthoate Component of N1999‐A2. (2010) (1)
New Acyclic Approach to 3-Amino-2,3,6-trideoxy-L-hexoses: A Stereocontrolled Synthesis of N-Benzoyl L-Daunosamine. (1986) (1)
Total Synthesis of 9-Membered Enediyne Antibiotic N1999—A2: Absolute Stereochemistry and DNA Cleavage (2004) (1)
Synthetic Study of Pinnatoxin A: Intramolecular Diels—Alder Approach to the AG-Ring. (1999) (1)
The 10-Membered Ring Analogues of Neocarzinostatin Chromophore: Design, Synthesis, and Mode of Decomposition. (1989) (1)
The First Total Synthesis of N1999‐A2: Absolute Stereochemistry and Stereochemical Implications into DNA Cleavage. (2002) (1)
Diastereoselective Deoxymercuration in an Acyclic System. A Remarkable Assistance by the Neighboring Carbonate Group. (1987) (1)
Efficient Route to the Nine-Membered Cyclic Diyne System: Tuning of the Extremely Facile Cope Rearrangement of 1,5-Diyne. (2010) (1)
Preface by Masahiro Hirama (Celebration of Professor Sho Ito) (2001) (1)
Asymmetric Induction in the Intramolecular Conjugate Addition of γ- or δ-Carbamoyloxy-α,β-Unsaturated Esters. A New Method for Diastereoselective Amination and Divergent Syntheses of 3-Amino-2,3,6-trideoxyhexoses (1989) (1)
Smartphone-based electrochemical immunosensor for ciguatoxins detection (2021) (1)
Total Synthesis of Cortistatin A and J (2013) (1)
Cell immunolocalization of ciguatoxin-like compounds in the benthic dinoflagellate Gambierdiscus australes M. Chinain & M.A. Faust by confocal microscopy. (2022) (1)
Palladium-Catalyzed Stereospecific Cyclization of Hydroxy Epoxides. Stereocontrolled Synthesis of cis- and trans-2-Alkenyl-3- hydroxytetrahydropyrans. (1991) (1)
Structure of Adduct Formed from α-Trichlorostannyl Ketone and Trichloroethynyltin a Direct Evidence for the Carbostannylation of Alkynyl Metals (1993) (1)
Total Syntheses of Dimmeric Lycopodium Alkaloid, Complanadines A and B (2019) (1)
Efficient Synthesis of a Carbocyclic Core Moiety with the Stereochemistry of the C-1027 Chromophore. (1996) (1)
Convenient Route to Both Enantiomerically Pure Forms of trans-4,5-Dihydroxy-2-cyclopenten-1-one: Efficient Synthesis of the Neocarzinostatin Chromophore Core. (2001) (1)
Synthesis and Binding of Simple Neocarzinostatin Chromophore Analogues to the Apoprotein. (1994) (1)
Synthesis of the LMN‐Ring Fragment of the Caribbean Ciguatoxin C‐CTX‐1. (2007) (0)
Synthetic Study of Kedarcidin Chromophore: Advanced Models and Their Chemical Behavior. (1997) (0)
OXIDATION OF BENZYL ETHERS TO BENZOATES BY OZONE (1984) (0)
A Concise Route to Two Distinct E‐Ring Structures of Ciguatoxins. (2007) (0)
Stereodivergent Total Synthesis of N-Acetylacosamine (I) and N-Benzoylristosamine (II). (1988) (0)
ortho‐Vinylation Reaction of Phenols with Ethyne. (1999) (0)
Asymmetric Dihydroxylation of Chiral Olefins. High Control of Diastereofacial Selection. (1993) (0)
Synthesis of a Hybrid Molecule (I) Containing Neocarzinostatin Chromophore Analogue and Minor Groove Binder. (2010) (0)
シグアトキシンの中員環エーテル,オキセペン,オキソカン及びオキソネンのエナンチオ選択的合成のための効率的環拡大戦略 (1996) (0)
Asymmetric Total Synthesis of (‐)‐Merrilactone A (I): Use of a Bulky Protecting Group as Long‐Range Stereocontrolling Element. (2006) (0)
Synthesis of the Maduropeptin Chromophore Aglycon (2008) (0)
Synthetic Study of Pinnatoxin A: Stereoselective Synthesis of the BCD-Ring Unit, a Novel 6,5,6-Bis-spiroketal System. (1998) (0)
Reinvestigation of the Diastereoselectivity of Kinetic Aldol Condensation of Cyclohexanone Lithium Enolate with Benzaldehyde. (1988) (0)
Concise Synthesis of the Tetracyclic Framework of Azadiradione: Tandem Radical Cyclization Route. (2013) (0)
Carbometalation of Ketone Enolates with 1‐Alkynes: An Alkylidenation Reaction of Silyl Enol Ethers Promoted by SnCl4‐Bu3N Reagent. (1993) (0)
Stereoselective Synthesis of the LM Ring Moiety of Ciguatoxin: Reagent Control of Asymmetric Dihydroxylation. (1998) (0)
REGIOSELECTIVE CONJUGATE ADDITION OF SULFONYLALLYL CARBANIONS TO α,β-UNSATURATED KETONES (1981) (0)
CHEMICAL REACTIONS OF O‐TROPOQUINONE AND ITS DERIVATIVES (1980) (0)
P-29 Synthetic Study of Polytheonamide A (2006) (0)
Enantiospecific Synthesis of the Spiroacetal Unit (I) of Avermectin B1a. (1987) (0)
Diastereofacial Selectivity in the Intramolecular Conjugate Addition of a Nitrogen Nucleophile. Stereocontrolled Piperidine Synthesis. (1988) (0)
Synthesis of the Bicyclic [7.3.0] Enediyne System of the Maduropeptin Chromophore: Remarkable Atropisomerism of Ansamacrolactam and Isomerization of the C4-C13 Double Bond (2004) (0)
Novel assembly of cyclic ethers by coupling alpha-chlorosulfides and alcohols. (2002) (0)
Synthesis of the Entire Carbon Framework (II) of the Kedarcidin Chromophore Aglycon. (2007) (0)
A Catalytically Enantioselective Michael Addition of a Malonate to Prochiral α,β‐Unsaturated Aldehydes and Ketones. (1993) (0)
Structure-based Analysis of Anti-ciguatoxin MAb 10C9Fab Recognition Mechanism for Poly-cyclic ethers (2008) (0)
1,2,3‐BENZOTROPOQUINONE (1980) (0)
Synthesis of the Bicyclic [7.3.0] Enediyne System of the Maduropeptin Chromophore: Remarkable Atropisomerism of Ansamacrolactam and Isomerization of the C4—C13 Double Bond. (2005) (0)
Ten-Membered Neocarzinostatin Chromophore Analogues Leading to σ, σ-Biradical via a Cumulene Intermediate. (1994) (0)
P-21 Highly Convergent Syntheses of Left Wings of Ciguatoxins (2006) (0)
Synthesis of Optically Active Macrocycles Consisting of Helical Chiral Unit 1,12‐Dimethylbenzo(c)phenanthrene‐5,8‐dicarboxylate as a Novel Chiral Building Block. (1996) (0)
Convergent Synthesis of a trans‐Fused 6‐7‐6 Tricyclic Ether System Based on a Ring‐Closing Metathesis Reaction. (1997) (0)
Direct Formation of Reactive Alkynyltrichlorotins from 1-Alkynes, SnCl4, and Bu3N. A Mild Alkynylation Reagent of Aldehydes, Acetals, and Enones. (1993) (0)
Stereocontrolled Synthesis of the HIJ Ring System of Ciguatoxin. (2010) (0)
New Synthetic Route to the Highly Strained Cores of C‐1027 and Neocarzinostatin Chromophores. (1999) (0)
Ciguatoxin preferentially activates Nav1.8 Na+ channels compared with those of Nav1.4 heterologously expressed in cell lines. (2007) (0)
43 Total Synthesis of Ciguatoxin CTX3C (2001) (0)
18 The Total Synthesis of Protected Aglycon of Kedarcidin Chromophore(Oral Presentation) (2008) (0)
A Very Short Route to the Functionalized A-Ring Moiety of Ciguatoxin. (2010) (0)
Convergent Synthesis of the IJKLM Ring Fragment of Ciguatoxin CTX3C. (2010) (0)
Diastereoselective Additions of Ethynyl Grignard Reagent to Erythrulose Derivatives. (2002) (0)
Structure-function relationships of ciguatoxin analogs studied on Nav1.2 and Nav1.8 channels (2008) (0)
SbF5‐Promoted Addition of Aldehydes to Alkynes. (1995) (0)
Enyne(3)cumulene. Synthesis and Mode of Aromatization. (1991) (0)
Synthetic Study of Zoanthamine Alkaloids: The C-Ring Model Possessing Three Consecutive Quaternary Carbons. (1999) (0)
Total Synthesis of Ciguatoxin CTX3C — A Venture into the Problems of Ciguatera Seafood Poisoning (2007) (0)
Asymmetric Michael Addition of Nitroalkanes to Prochiral Acceptors Catalyzed by Proline Rubidium Salts. (1997) (0)
Synthesis and Chemistry of Nine Membered Cyclic Enediyne Chromophores of Chromoprotein Antitumor Antibiotics (1997) (0)
Stereocontrolled Synthesis of the Northern Part (I) of Potent Proteasome Inhibitor TMC-95A. (2002) (0)
15 Generation of Anti-ciguatoxin Antibodies for Sandwich ELISA Detection of Pacific Ciguatoxins(Oral Presentation) (2011) (0)
Synthesis of Cyclopent-2-enones Through Stepwise (3 + 2) Cycloaddition of Simple Silyl Enol Ethers and Alk-1-ynes. (1994) (0)
TOTAL SYNTHESIS OF DISODIUM PREPHENATE (1978) (0)
The First F‐Ring Modified Ciguatoxin Analogue Showing Significant Toxicity. (2010) (0)
Synthesis and Absolute Stereochemistry of the Amino Sugar Moiety of Antibiotic C-1027 Chromophore (I). (1993) (0)
A Formal Total Synthesis of (+)‐Pinnatoxin A. (2005) (0)
Reactions of Neocarzinostatin Chromophore Analogues with Molecular Oxygen. (1994) (0)
クムレン中間体を経由してσ,σ-ビラジカルを発生する十員環ネオカルチノスタチン発色団類似体の合成 (1994) (0)
Recent Advances in the Synthetic Studies of Nine‐Membered Enediyne Antitumor Antibiotics (2011) (0)
75 SYNTHETIC STUDIES ON (+)-AVERMECTIN B_ : AN EXPEDITIOUS APPROACH TO THE OXAHYDRINDENE UNIT (1986) (0)
Rhodium-Catalyzed Cross Coupling of Unactivated Allenes and 1-Alkynes. (1994) (0)
The Absolute Configuration and Total Synthesis of Korormicin. (2000) (0)
P-133 Potent Neutralization of Ciguatoxin CTX3C by Monoclonal Antibodies (2006) (0)
The First Total Synthesis of Gravicycle. (2012) (0)
Chemical syntheses and biological activities of ciguatoxins and their analogs (2004) (0)
Allylgallation reaction of carboncarbon triple bonds with allylsilanes and GaCl3 (2010) (0)
Convergent Synthesis of the ABCDE Ring Framework of Ciguatoxin. (1999) (0)
Stereoselective Hydrogenation of Tetrasubstituted Enones. (1997) (0)
Synthetic Study of the Kedarcidin Chromophore: Efficient Construction of the Aryl Alkyl Ether Linkage. (1999) (0)
Total synthesis and biomimetic studies of nine-membered enediynes (2014) (0)
Asymmetric Dihydroxylation of Alkenes with Osmium Tetroxide: Chiral N,N′-Dialkyl-2,2′-bipyrrolidine Complex. (1989) (0)
2,6‐Divinylation of Phenols with Ethyne. (1997) (0)
A New Method for Diastereoselective Amination in Acyclic Systems and Total Synthesis of Amino Sugars (1987) (0)
EFFECTS OF SYNTHETIC CIGUATOXIN CTX3C AND GAMBIERONE IN NEURONAL CELLS (2018) (0)
Remarkable Selectivity in Derivatization and Protection of Hydroxy Groups of 51‐HydroxyCTX3C: Chemoselective Synthesis of Biotin‐Conjugated Ciguatoxin Derivatives. (2010) (0)
P-68 Synthetic Study of C-1027 Chromophore (2006) (0)
Stereoselective Synthesis of (+)‐Swainsonine and (‐)‐8,8a‐Di‐epi‐ swainsonine. (1995) (0)
Convergent Synthesis of the ABCDE Ring System (I) of Ciguatoxin CTX3C. (2002) (0)
Copper(II)-Catalyzed O-Arylation of Tertiary Alcohols with Arylbismuth(III) Reagents: A Convenient System for Aryl Transfer. (2012) (0)
Total Synthesis of Merrilactone A: Long-Range Stereocontrol and Asymmetric Desymmetrization (2007) (0)
PB38 SYNTHETIC STUDIES TOWARD AVERMECTIN B1a AND MILBEMYCIN α1 (1988) (0)
Convenient Route to Derivatives of the 2‐Deoxysugar Subunits of the Kedarcidin Chromophore: L‐Mycarose and L‐Kedarosamine. (1999) (0)
1P-057 Molecular recognition mechanism of an anti-ciguatoxin antibody : mutational study and small-molecule binding screen(The 46th Annual Meeting of the Biophysical Society of Japan) (2008) (0)
Stereocontrolled Construction of the Hexahydrobenzofuran Subunit of the Avermectins and the Milbemycins: The Aldol Strategy. (1988) (0)
Practical Entry into the HIJKLM Ring Segment of Ciguatoxin CTX3C. (2001) (0)
Highly Enantioselective Dihydroxylation of trans-Disubstituted and Monosubstituted Olefines. (1990) (0)
Neocarzinostatin Complex: Chromophore Analogues, Binding Structure and Stabilization Mechanism (2010) (0)
Convergent Synthesis of the EFGH Ring Fragment (I) of Ciguatoxin CTX3C. (2002) (0)
ortho‐Vinylation Reaction of Phenols (1996) (0)
Synthesis of 13C‐Labeled, Bicyclic Mimetics of Natural Enediynes. (2003) (0)
ortho-Vinylation Reaction of Anilines. (1998) (0)
Synthesis and Reactions of Monosilylated 1,3,5-Hexatriyne and 1,3,5,7- Octatetrayne. Total Synthesis of Caryoynencins. (1994) (0)
A convergent total synthesis of the kedarcidin chromophore: 20-years in the making (2019) (0)
2P047 The structural and thermodynamic analysis of the interaction between ciguatoxin and its Antibody 10C9 Fab(Proteins-structure and structure-function relationship,Poster Presentations) (2007) (0)
Evidence for Spontaneous Cycloaromatization of Nine‐Membered Monocyclic Enediyne. (1999) (0)
Conjugate Addition of Internal Nucleophile to Chiral Vinyl Sulfoxides with Stereogenic Center at the Allylic Carbon. “Intramolecular” Double Asymmetric Induction. (1988) (0)
Synthesis of exo‐Enynes by Ruthenium‐Catalyzed Cross‐Coupling Reaction of Hydroxy Allenes and 1‐Alkynes. (1996) (0)
Stereoselective Synthesis of Caribbean Ciguatoxin M‐Ring Using [2 + 2] Photocyclization. (2011) (0)
Synthetic Study of C-1027 Chromophore: Enantioselective Synthesis of β-Tyrosine Moiety and Effective Aryl Ether Formation. (1999) (0)
Expeditious Synthesis of Enantiomerically Pure trans‐4,5‐Dihydroxy‐2‐ cyclopenten‐1‐one. (1996) (0)
α‐Alkenylation of Ketones with 1‐Alkynes (1995) (0)
Chemistry and Antimicrobial Activities of 3,5,7,9-Decatetrayn-2-ol and Related Compounds. (2010) (0)
Convergent Synthesis of the ABCDE-Ring Fragment of the Caribbean Ciguatoxin C-CTX-1. (2007) (0)
Convergent Synthesis of the trans-Fused 6-n-6-6 (n = 7-10) Tetracyclic Ether System Based on a Ring-Closing Metathesis Reaction. (1998) (0)
Voltage sensors influence ciguatoxin effects on Nav1.4 Na+ channels (2006) (0)
Alkynyldichlorogalliums are Unstable in Hydrocarbon Solvents. Dimerization of Alkynyldichlorogalliums via Carbogallation. (1996) (0)
Extensive Ring‐Expansion Strategy for the Enantioselective Synthesis of the Medium Ring Ethers, Oxepene, Oxocane, and Oxonene, of Ciguatoxin. (1997) (0)
CARBAMATE-MEDIATED 1,3-ASYMMETRIC INDUCTION. A STEREOSELECTIVE SYNTHESIS OF ACYCLIC 1,3-DIOL SYSTEMS (1983) (0)
Palladium‐Catalyzed Coupling of Alkenyl Iodides with Ethynyl Oxiranes: Synthesis of Epoxy Enediyne Core Intermediates Related to Neocarzinostatin Chromophore. (1997) (0)
New Convenient, Enantiospecific Synthesis of (S,S)‐ and (R,R)‐2,2′‐ Bipyrrolidine Derivatives. (1996) (0)
ISOLATION, CHARACTERIZATION AND MOLECULAR STRUCTURE OF O‐TROPOQUINONE (1978) (0)
Erratum to “Enantio-face control by molecular sieves in the asymmetric Diels–Alder reaction” (2000) (0)
Synthesis and Chemistry of Chromoprotein Antitumor Antibiotics: Nine- Membered Enediynes are Equilibrated with p-Benzyne Type Biradicals (1997) (0)
Friedel-Crafts β-Silylvinylations. (1997) (0)

This paper list is powered by the following services:

What Schools Are Affiliated With Masahiro Hirama?

Masahiro Hirama is affiliated with the following schools:

Tohoku University
Kyoto University