Masao Endoh
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Medical Philosophy
Masao Endoh's Degrees
- PhD Pharmacology University of Tokyo
- Doctorate Medicine University of Tokyo
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(Suggest an Edit or Addition)Masao Endoh's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Actions of Sympathomimetic Amines on the Ca2+ Transients and Contractions of Rabbit Myocardium: Reciprocal Changes in Myofibrillar Responsiveness to Ca2+ Mediated Through α‐ and β‐Adrenoceptors (1988) (390)
- Modification of myofibrillar responsiveness to Ca++ as an inotropic mechanism. (1986) (229)
- Force-frequency relationship in intact mammalian ventricular myocardium: physiological and pathophysiological relevance. (2004) (228)
- Positive inotropic effect of amrinone in relation to cyclic nucleotide metabolism in the canine ventricular muscle. (1982) (193)
- Effects of new inotropic agents on cyclic nucleotide metabolism and calcium transients in canine ventricular muscle. (1986) (183)
- Myocardial alpha 1-adrenoceptors mediate positive inotropic effect and changes in phosphatidylinositol metabolism. Species differences in receptor distribution and the intracellular coupling process in mammalian ventricular myocardium. (1991) (141)
- Characterization of positive inotropic effect of endothelin on mammalian ventricular myocardium. (1991) (132)
- Attenuation of muscarinic cholinergic inhibition by islet-activating protein in the heart. (1985) (102)
- Cardiac-Specific Overexpression of Diacylglycerol Kinase &zgr; Prevents Gq Protein-Coupled Receptor Agonist-Induced Cardiac Hypertrophy in Transgenic Mice (2005) (89)
- Effects of levosimendan on myocardial contractility and Ca2+ transients in aequorin-loaded right-ventricular papillary muscles and indo-1-loaded single ventricular cardiomyocytes of the rabbit. (1998) (85)
- The effects of various drugs on the myocardial inotropic response. (1995) (84)
- Adenosine antagonizes the positive inotropic action mediated via β-, but not α-adrenoceptors in the rabbit papillary muscle (1980) (79)
- Endothelin: receptor subtypes, signal transduction, regulation of Ca2+ transients and contractility in rabbit ventricular myocardium. (1998) (79)
- Cardiac Ca2+ signaling and Ca2+ sensitizers. (2008) (78)
- Species‐related differences in inotropic effects of angiotensin II in mammalian ventricular muscle: receptors, subtypes and phosphoinositide hydrolysis (1995) (76)
- Mechanisms of action of novel cardiotonic agents. (2002) (75)
- Role of Na+/Ca2+ exchange in endothelin‐1‐induced increases in Ca2+ transient and contractility in rabbit ventricular myocytes: pharmacological analysis with KB‐R7943 (1999) (69)
- Signal transduction and Ca2+ signaling in intact myocardium. (2006) (68)
- Correlation of cyclic AMP and cyclic GMP levels with changes in contractile force of dog ventricular myocardium during cholinergic antagonism of positive inotropic actions of histamine, glucagon, theophylline and papaverine. (1979) (65)
- Inotropic effects of OR-1896, an active metabolite of levosimendan, on canine ventricular myocardium. (2000) (64)
- Pharmacological characteristics of the positive inotropic effect of angiotensin II in the rabbit ventricular myocardium (1993) (64)
- Effects of OR-1896, an active metabolite of levosimendan, on contractile force and aequorin light transients in intact rabbit ventricular myocardium. (2000) (62)
- Mode and mechanism of action of 3,4-dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-2(1H)- quinolinone (OPC-8212), a novel positive inotropic drug, on the dog heart. (1984) (61)
- α-Adrenoceptors in the ventricular myocardium: clonidine, naphazoline and methoxamine as partial α-agonists exerting a competitive dualism in action to phenylephrine (1976) (59)
- Mechanism of Action of Ca2+ Sensitizers—Update 2001 (2001) (56)
- Pharmacological properties of endothelin receptor subtypes mediating positive inotropic effects in rabbit heart. (1994) (53)
- alpha-Adrenoceptors mediating positive inotropic effects on the ventricular myocardium: some aspects of structure-activity relationship of sympathomimetic amines. (1976) (53)
- Effects of a Cardiotonic Quinolinone Derivative Y-20487 on the Isoproterenol-Induced Positive Inotropic Action and Cyclic AMP Accumulation in Rat Ventricular Myocardium: Comparison with Rolipram, Ro 20-1724, Milrinone, and Isobutylmethylxanthine (1992) (52)
- Modification by Islet‐Activating Protein of Direct and Indirect Inhibitory Actions of Adenosine on Rat Atrial Contraction in Relation to Cyclic Nucleotide Metabolism (1983) (51)
- CHARACTERIZATION OF ADRENOCEPTORS MEDIATING POSITIVE INOTROPIC RESPONSES IN THE VENTRICULAR MYOCARDIUM OF THE DOG (1978) (50)
- Effects of cyclopiazonic acid and ryanodine on cytosolic calcium and contraction in vascular smooth muscle (1996) (49)
- Does the positive inotropic action of a novel cardiotonic agent, MCI-154, involve mechanisms other than cyclic AMP? (1987) (47)
- Signal Transduction and Ca2+ Signaling in Contractile Regulation Induced by Crosstalk Between Endothelin-1 and Norepinephrine in Dog Ventricular Myocardium (2003) (46)
- Different Mechanisms Involved in the Positive Inotropic Effects of Benzimidazole Derivative UD‐CG 115 BS (Pimobendan) and Its Demethylated Metabolite UD‐CG 212 Cl in Canine Ventricular Myocardium (1991) (46)
- Concentration- and time-dependence of phosphoinositide hydrolysis induced by endothelin-1 in relation to the positive inotropic effect in the rabbit ventricular myocardium. (1992) (44)
- Differential effects of sulmazole (AR-L 115 BS) on contractile force and cyclic AMP levels in canine ventricular muscle: comparison with MDL 17,043. (1985) (44)
- Lack of correlation between the positive inotropic effect evoked by alpha-adrenoceptor stimulation and the levels of cyclic AMP and/or cyclic GMP in the isolated ventricle strip of the rabbit. (1978) (43)
- Regulation of Myocardial Contractility Via Adrenoceptors: Differential Mechanisms of α- and β-Adrenoceptor-Mediated Actions (1986) (43)
- Acute heart failure: inotropic agents and their clinical uses (2006) (43)
- Positive inotropic effects of phenylephrine in the isolated rabbit papillary muscle mediated both by α-and β-adrenoceptors (2004) (43)
- Changes in intracellular Ca2+ mobilization and Ca2+ sensitization as mechanisms of action of physiological interventions and inotropic agents in intact myocardial cells. (1998) (41)
- Pharmacological differentiation of synergistic contribution of L-type Ca2+ channels and Na+/H+ exchange to the positive inotropic effect of phenylephrine, endothelin-3 and angiotensin II in rabbit ventricular myocardium (1996) (40)
- Differentiation by cholinergic stimulation of positive inotropic actions mediated via alpha- and beta-adrenoceptors in the rabbit heart. (1979) (40)
- Influence of a Na+-H+ exchange inhibitor ethylisopropylamiloride, a Na+-Ca2+ exchange inhibitor KB-R7943 and their combination on the increases in contractility and Ca2+ transient induced by angiotensin II in isolated adult rabbit ventricular myocytes (1999) (39)
- The time course of the effects of β-and α-adrenoceptor stimulation by isoprenaline and methoxamine on the contractile force and cAMP level of the isolated rabbit papillary muscle (2004) (38)
- Characterization of the endothelin-1-induced regulation of L-type Ca2+ current in rabbit ventricular myocytes (1999) (37)
- Negative chronotropic and inotropic effects of endothelin isopeptides in mammalian cardiac muscle. (1997) (35)
- Muscarinic regulation of Ca2+ signaling in mammalian atrial and ventricular myocardium. (1999) (35)
- ROS generated during early reperfusion contribute to intermittent hypobaric hypoxia-afforded cardioprotection against postischemia-induced Ca(2+) overload and contractile dysfunction via the JAK2/STAT3 pathway. (2015) (35)
- Inotropic response of rabbit ventricular myocytes to endothelin-1: difference from isolated papillary muscles. (2001) (34)
- Effects of endothelin-1 on [Ca2+]i-shorteningtrajectory and Ca2+ sensitivity in rabbit single ventricular cardiomyocytes loaded with Indo-1/AM: Comparison with the effects of phenylephrine and angiotensin II (1996) (34)
- Pharmacological analysis by HOE642 and KB‐R9032 of the role of Na+/H+ exchange in the endothelin‐1‐induced Ca2+ signalling in rabbit ventricular myocytes (2000) (33)
- Effects of a new cardiotonic agent 1,2-dihydro-6-methyl-2-oxo-5-[imidazo (1,2-a) pyridin-6-yl]-3-pyridine carbonitrile hydrochloride monohydrate (E-1020) on contractile force and cyclic AMP metabolism in canine ventricular muscle. (1990) (33)
- Effects of the positive inotropic agent Org 30029 on developed force and aequorin light transients in intact canine ventricular myocardium. (1993) (32)
- Dual regulation of myofilament Ca2+ sensitivity by levosimendan in normal and acidotic conditions in aequorin‐loaded canine ventricular myocardium (2005) (31)
- Differential effects of Ro 20-1724 and isobutylmethylxanthine on the basal force of contraction and beta-adrenoceptor-mediated response in the rat ventricular myocardium. (1990) (30)
- Angiotensin II activation of a chloride current in rabbit cardiac myocytes. (1995) (30)
- Influence of aging on the contractile response to endothelin of rat thoracic aorta. (1991) (29)
- Signal transduction of myocardial α1-adrenoceptors : regulation of ion channels, intracellular calcium, and force of contraction―a review (1991) (29)
- Relationship between the increase in Ca2+ transient and contractile force induced by angiotensin II in aequorin-loaded rabbit ventricular myocardium. (1998) (29)
- Angiotensin II increases L-type Ca2+ current in gramicidin D-perforated adult rabbit ventricular myocytes: comparison with conventional patch-clamp method (2002) (28)
- Ca2+ sensitizer Org-30029 reverses acidosis- and BDM-induced contractile depression in canine myocardium. (1996) (28)
- Effects of papaverine on isolated rabbit papillary muscle. (1975) (28)
- DIFFERENTIAL RESPONSES TO CARBACHOL, SODIUM NITRO‐PRUSSIDE AND 8‐BROMO‐GUANOSINE 3‘,5’‐MONOPHOSPHATE OF CANINE ATRIAL AND VENTRICULAR MUSCLE (1981) (27)
- Increase in Myofibrillar Ca2+ Sensitivity Induced by UD-CG 212 Cl, an Active Metabolite of Pimobendan, in Canine Ventricular Myocardium (2001) (27)
- Dual inhibition of muocardial function through muscarinic and adenosine receptors in the mammalian heart (1987) (26)
- Regulation of myocardial contractility by a downstream mechanism. (1998) (26)
- Effects of OR-1896, a metabolite of levosimendan, on force of contraction and Ca2+ transients under acidotic condition in aequorin-loaded canine ventricular myocardium (2002) (25)
- (-)-Enantiomer EMD 57439 antagonizes the Ca2+ sensitizing effect of (+)-enantiomer EMD 57033 on diastolic function but not on systolic function in rabbit ventricular cardiomyocytes. (1999) (25)
- Dissociation of the positive inotropic effect of methoxamine from the hydrolysis of phosphoinositide in rabbit ventricular myocardium: a comparison with the effects of phenylephrine and the subtype of the alpha-1 adrenoceptor involved. (1994) (25)
- Further characterization of the myocardial alpha-adrenoceptors mediating positive inotropic effects in the rabbit myocardium. (1988) (24)
- Effects of a Novel Cardiotonic Agent (±)-6-[3-(3,4‐Dimethoxybenzylamino)-2‐Hydroxypropoxy]-2(1H)-Quinolinone (OPC‐18790) on Contractile Force, Cyclic AMP Level, and Aequorin Light Transients in Dog Ventricular Myocardium (1994) (24)
- Calcium compartments in vascular smooth muscle cells as detected by aequorin signal (1995) (24)
- Twitch potentiation by rest in canine ventricular muscle: effects of theophylline. (1981) (22)
- The therapeutic potential of novel cardiotonic agents (2003) (22)
- Stimulation by phenylephrine of adrenergic alpha- and beta-receptors in the isolated perfused rabbit heart (2004) (21)
- Dissociation of E-4031 from the HERG channel caused by mutations of an amino acid results in greater block at high stimulation frequency. (2003) (21)
- Acetylcholine and adenosine activate the G protein-gated muscarinic K+ channel in ferret ventricular myocytes (1995) (21)
- Myocardial α-adrenoceptors : multiplicity of subcellular coupling processes (1991) (21)
- Frequency-dependence of the positive inotropic effect of methoxamine and naphazoline mediated by α-adrenoceptors in the isolated rabbit papillary muscle (2004) (21)
- Inotropic effects of staurosporine, NA 0345 and H-7, protein kinase C inhibitors, on rabbit ventricular myocardium: selective inhibition of the positive inotropic effect mediated by alpha 1-adrenoceptors. (1993) (20)
- Differential alteration of cardiotonic effects of EMD 57033 and beta-adrenoceptor agonists in volume-overload rabbit ventricular myocytes. (2000) (19)
- Inhibition by theophylline of the early component of canine ventricular contraction. (1982) (19)
- Failure of dibutyryl and 8-bromo-cyclic GMP to mimic the antagonistic action of carbachol on the positive inotropic effects of sympathomimetic amines in the canine isolated ventricular myocardium. (1979) (19)
- A novel cardiotonic agent SCH00013 acts as a Ca++ sensitizer with no chronotropic activity in mammalian cardiac muscle. (1998) (19)
- On the mechanism of action of the beta-1 partial agonist denopamine in regulation of myocardial contractility: effects on myocardial alpha adrenoceptors and intracellular Ca++ transients. (1993) (19)
- Antiadrenergic effects of endothelin-1 on the L-type Ca2+ current in dog ventricular myocytes. (2000) (19)
- Involvement of cyclic AMP in the positive inotropic effect of OPC-8212, a new cardiotonic agent, on the canine ventricular muscle. (1984) (19)
- Accumulation of cAMP and positive inotropic effect evoked by isoproterenol under the graded inhibition of phosphodiesterase by papaverine in the isolated rabbit papillary muscle. (1975) (18)
- Differential action of a protein tyrosine kinase inhibitor, genistein, on the positive inotropic effect of endothelin‐1 and norepinephrine in canine ventricular myocardium (2005) (18)
- The time course of changes in cyclic nucleotide levels during cholinergic inhibition of positive inotropic actions of isoprenaline and theophylline in the isolated canine ventricular myocardium (1980) (18)
- Effects of vasopressin on phosphoinositide hydrolysis and myocardial contractility. (1992) (18)
- Biphasic inotropic response to endothelin-1 in the presence of various concentrations of norepinephrine in dog ventricular myocardium. (2000) (18)
- Mechanisms of endothelin‐1‐induced decrease in contractility in adult mouse ventricular myocytes (2007) (18)
- An amino acid residue whose change by mutation affects drug binding to the HERG channel (2001) (17)
- Influence of temperature on the positive inotropic effects mediated by α- and β-adrenoceptors in the isolated rabbit papillary muscle (1975) (17)
- The effects of theophylline on aequorin light transients and force in the isolated dog right ventricular myocardium. (1994) (17)
- The positive inotropic effect and the hydrolysis of phosphoinositide induced by endothelin-3 in rabbit ventricular myocardium: inhibition by a selective antagonist of ET(A) receptors, FR139317. (1996) (17)
- Species‐dependent differences in inotropic effects and phosphoinositide hydrolysis induced by endothelin‐3 in mammalian ventricular myocardium (1997) (16)
- Inhibition of cyclic AMP phosphodiesterase activity and myocardial contractility: effects of cilostamide, a novel PDE inhibitor, and methylsiobutylxanthine on rabbit and canine ventricular muscle. (1980) (16)
- Comparison of the mechanisms underlying the positive inotropic actions of dopamine, adrenaline and isoprenaline on the isolated rabbit papillary muscle (1977) (16)
- EFFECTS OF DOPAMINE ON SINUS RATE AND VENTRICULAR CONTRACTILE FORCE OF THE DOG HEART in vitro AND in vivo (1975) (16)
- Relationship between relaxation and cyclic GMP formation caused by nicorandil in canine mesenteric artery (1983) (15)
- Differential inhibitory action of phorbol-12,13-dibutyrate on the positive inotropic effect of endothelin-1 and Bay K 8644 in the isolated rabbit papillary muscle. (1991) (15)
- Pharmacological evidence for α1D‐adrenoceptors in the rabbit ventricular myocardium: analysis with BMY 7378 (1997) (15)
- Frequency dependence of cyclic AMP in mammalian myocardium (1976) (15)
- Effects of 2-nicotinamidethyl nitrate (SG-75), a new antianginal drug, on the cyclic AMP phosphodiesterase activity. (1980) (15)
- Relationship between the level of cAMP and the contractile force under stimulation of α- and β-adrenoceptors by phenylephrine in the isolated rabbit papillary muscle (1976) (15)
- Molecular and Cellular Mechanisms of Cardiovascular Regulation (1996) (15)
- Selective inhibition by phorbol 12,13-dibutyrate of the alpha 1-receptor-mediated positive inotropic effect. (1993) (14)
- Could Ca2+ sensitizers rescue patients from chronic congestive heart failure? (2007) (14)
- Cardiac alpha(1)-adrenoceptors that regulate contractile function: subtypes and subcellular signal transduction mechanisms. (1996) (13)
- Dissociation of cyclic AMP and contractile responses to isoprenaline: effects of a dihydropyridine derivative, nicardipine (YC-93), on canine ventricular muscle. (1980) (13)
- Cardiac α1-Adrenoceptors and Inotropy: Myofilament Ca2+ Sensitivity, Intracellular Ca2+ Mobilization, Signaling Pathway, and Pathophysiological Relevance. (2016) (13)
- Effects of Nicorandil and Its Interaction with Isoproterenol on Force of Contraction and Cyclic Nucleotide Levels of Canine Atrial Muscle: Comparison with Carbachol (1983) (13)
- Regulation of the intracellular Ca++ transient and Ca++-sensitivity of myofibrils via α- and β-adrenoceptors in the rabbit papillary muscle (1984) (13)
- The G-protein G(o) in mammalian cardiac muscle: localization and coupling to A1 adenosine receptors. (1995) (12)
- Methoxamine-induced inhibition of the positive inotropic effect of endothelin via alpha1-adrenoceptors in the rabbit heart. (1996) (12)
- Phorbol ester does not mimic, but antagonizes the alpha-adrenoceptor-mediated positive inotropic effect in the rabbit papillary muscle (1988) (12)
- Phorbol-12,13-dibutyrate antagonizes the alpha 1-adrenoceptor-mediated positive inotropic effect in the rabbit ventricular myocardium. (1990) (12)
- Enantiomers of dobutamine increase the force of contraction via beta adrenoceptors, but antagonize competitively the positive inotropic effect mediated by alpha-1 adrenoceptors in the rabbit ventricular myocardium. (1988) (11)
- Effect of (+)-niguldipine on myocardial α1-adrenoceptors in the rabbit (1992) (11)
- Cardiac α1-Adrenoceptors that regulate contractile function: Subtypes and subcellular signal transduction mechanismsthat regulate contractile function: Subtypes and subcellular signal transduction mechanisms (1996) (11)
- Potent inhibitory action of chlorethylclonidine on the positive inotropic effect and phosphoinositide hydrolysis mediated via myocardial alpha1-adrenoceptors in the rabbit ventricular myocardium (1991) (11)
- Effects of prostaglandin E1 on the positive inotropic actions of noradrenaline, nerve stimulation and calcium in the isolated blood-perfused papillary muscle of the dog. (1976) (11)
- Chelerythrine and genistein inhibit the endothelin-1-induced increase in myofilament Ca(2+) sensitivity in rabbit ventricular myocytes. (2001) (11)
- Myocardial α1A-adrenoceptor subtypes in rabbit: differentiation by a selective antagonist, HV723 (1993) (11)
- (+/-)-tamsulosin, an alpha 1A-adrenoceptor antagonist, inhibits the positive inotropic effect but not the accumulation of inositol phosphates in rabbit heart. (1996) (10)
- Role of alpha1A adrenoceptor subtype in production of the positive inotropic effect mediated via myocardial alpha, adrenoceptors in the rabbit papillary muscle: influence of selective alpha1A subtype antagonists WB 4101 and 5-methylurapidil (1992) (10)
- Inhibitory Action of the Phosphatase Inhibitor Cantharidin on the Endothelin‐1‐Induced and the Carbachol‐Induced Negative Inotropic Effect in the Canine Ventricular Myocardium (2003) (10)
- Effects of papaverine and its interaction with isoprenaline and carbachol on the contractile force and cyclic nucleotide levels of the canine ventricular myocardium (1979) (10)
- Investigation on SCH00013, a Novel Cardiotonic Agent with Ca++ Sensitizing Action (1999) (10)
- Decrease in Ca(2+)-sensitizing effect of UD-CG 212 Cl, a metabolite of pimobendan, under acidotic condition in canine ventricular myocardium. (2001) (10)
- Overexpression of diacylglycerol kinase zeta inhibits endothelin-1-induced decreases in Ca2+ transients and cell shortening in mouse ventricular myocytes. (2008) (10)
- Differential inhibition by the Rho kinase inhibitor Y-27632 of the increases in contractility and Ca2+ transients induced by endothelin-1 in rabbit ventricular myocytes (2005) (10)
- Differential Effects of Protein Kinase C Activators and Inhibitors on α- and β-Adrenoceptor-mediated Positive Inotropic Effect in Isolated Rabbit Papillary Muscle (1997) (9)
- Pharmacological characterization of effects of UK-1745, a novel cardiotonic agent with beta-adrenoceptor-blocking action, in aequorin-loaded canine right ventricular muscle. (1999) (9)
- Effects of 8-S-benzyl cyclic AMP on mechanical characteristics and cyclic AMP levels of the canine ventricular myocardium. (1980) (9)
- Frequency-dependent inhibition of the intracellular calcium transients by calmodulin antagonists in the aequorin-injected rabbit papillary muscle. (1989) (9)
- Does nitric oxide contribute to the negative chronotropic and inotropic effects of endothelin-1 in the heart? (1997) (9)
- Pronounced direct inhibitory action mediated by adenosine A1 receptor and pertussis toxin-sensitive G protein on the ferret ventricular contraction (1993) (9)
- Influence of stress and antidepressant treatment on 5-HT-stimulated phosphoinositide hydrolysis in rat brain. (1992) (9)
- Wortmannin inhibits the myofilament Ca2+ sensitization induced by endothelin-1. (2005) (9)
- Amrinone, Forerunner of Novel Cardiotonic Agents, Caused Paradigm Shift of Heart Failure Pharmacotherapy (2013) (9)
- Mechanisms of Novel Cardiotonic Agents Developed to Treat the Failing Heart Syndrome (1996) (9)
- Pharmacology of SCH00013: a novel Ca2+ sensitizer. (2006) (8)
- Pharmacological characteristics of adenosine-induced inhibition of dog ventricular contractility: dependence on the pre-existing level of β-adrenoceptor activation (1991) (8)
- Influence of temperature and frequency on the positive inotropic action of phenylephrine in the isolated rabbit papillary muscle. (1977) (8)
- Mechanism of cardiovascular action of trapidil. (1980) (8)
- Adrenoceptors mediating the positive inotropic effect in the canine atrial myocardium. (1981) (8)
- Effects of endothelin-1 on [Ca2+]i-shortening trajectory and Ca2+ sensitivity in rabbit single ventricular cardiomyocytes loaded with indo-1/AM: comparison with the effects of phenylephrine and angiotensin II. (1996) (8)
- Cholera toxin-induced changes in force of contraction and cyclic AMP levels in canine ventricular myocardium: inhibition by carbachol. (1984) (8)
- Modulation by aging of the coronary vascular response to endothelin-I in the rat isolated perfused heart (8)
- [Myocardial contraction and relaxation: modulation by inotropic agents]. (1990) (8)
- Inotropic Versus Chronotropic, Dromotropic, and Coronary Vasodilator Actions of DPI 201–106, a Novel Positive Inotropic Agent, in the Dog Heart (1987) (8)
- Differential inotropic effects of endothelin-1, angiotensin II, and phenylephrine induced by crosstalk with cAMP-mediated signaling process in dog ventricular myocardium. (2004) (8)
- Investigation on SCH00013, a Novel Cardiotonic Agent with Ca++ Sensitizing Action (1999) (7)
- Cross-talk between β1-adrenoceptors and ETA receptors in modulation of the slow component of delayed rectifier K+ currents (2005) (7)
- Proceedings: Beta-and-or alpha-adrenoceptors in the ventricular muscle of the rabbit? (1974) (7)
- Adenosine antagonizes the positive inotropic action mediated via beta-, but not alpha-adrenoceptors in the rabbit papillary muscle. (1980) (7)
- The Role of Phosphoinositide Hydrolysis in the Regulation of Cardiac Function via α-Adrenergic, Endothelin, and Angiotensin Receptors (1996) (7)
- Cyclic AMP metabolism in intact rat ventricular cardiac myocytes: Interaction of carbachol with isoproterenol and 3-isobutyl-1-methylxanthine (1993) (7)
- Enhancement of 5-hydroxytryptamine-stimulated phosphoinositide hydrolysis in the rat cerebral cortex by repeated immobilization stress. (1995) (7)
- A Na+ channel agonist: a potential cardiotonic agent with a novel mechanism? (2004) (7)
- Acidic pH-induced contractile dysfunction via downstream mechanism: identification of pH-sensitive domain in troponin I. (2001) (7)
- Does levosimendan act as a Ca2+ sensitizer or PDE3 inhibitor?: Commentary on Orstavik et al., Br J Pharmacol 171: 5169–5181 (2015) (6)
- Influence of temperature on the positive inotropic effects mediated by alpha-and-beta-adrenoceptors in the isolated rabbit papillary muscle. (1975) (6)
- Differential effects of isoproterenol on the canine atrial action potential in the presence of carbachol or nicorandil. (1987) (6)
- Effects of a novel cardiotonic agent, Org 9731, on force and aequorin light transients in intact ventricular myocardium of the dog: involvement of a cyclic AMP-mediated mechanism and myofibrillar responsiveness to Ca2+ ions. (1995) (6)
- Positive Inotropic Effect of &agr;1‐Adrenoceptor Stimulation in Dog Ventricular Myocardium (2001) (5)
- Relaxation of airway smooth muscle induced by potassium in the presence of Ca-antagonists. (1989) (5)
- Inhibition of the positive inotropic effect of dopamine by YM-09538 with alpha- and beta-adrenoceptor antagonistic action in the rabbit papillary muscle. (1983) (5)
- Myocardial a1-Adrenoceptors Mediate Positive Inotropic Effect and Changes in Phosphatidylinositol Metabolism (2005) (5)
- Basic and Clinical Characteristics of PDE 3 Inhibitors as Cardiotonic Agents (2007) (5)
- Differential regulation of intracellular Ca2+ signalling induced by high K+ and endothelin-1 in single smooth muscle cells of intact canine basilar artery: detection by means of confocal laser microscopy. (1999) (5)
- Pharmacology of loprinone (E-1020), a new pyridinone inodilator, as a therapeutic agent for acute heart failure (1993) (5)
- The Na+-Ca2+ exchanger contributes to beta-adrenoceptor mediated positive inotropy in mouse heart. (2002) (5)
- Investigation on SCH00013, a Novel Cardiotonic Agent with Ca++ Sensitizing Action (1999) (5)
- Tight coupling between the rate of rise of Ca2+ transient and peak twitch contraction in guinea-pig papillary muscle. (1999) (5)
- Investigation on SCH00013, a Novel Cardiotonic Agent with Ca++ Sensitizing Action (1999) (5)
- Inotropic effects of endothelin on mammalian ventricular contractility. (1991) (5)
- Effects of calcium-antagonistic coronary vasodilators, nifedipine and verapamil, on ventricular automaticity of the dog (1978) (4)
- Differential effects of theophylline on the early and late component of the dog ventricular contraction (1979) (4)
- Calcium Signaling and Pharmacology of Cardiotonic Agents (1995) (4)
- The preferential inhibition of α1- over β-adrenoceptor-mediated positive inotropic effect by organic calcium antagonists in the rabbit papillary muscle (1990) (4)
- Differential effects of Ro 20-1724 and milrinone on the force of contraction and β-adrenoceptor-mediated response in the rat ventricular myocardium (1990) (4)
- Receptor subtypes mediating the inotropic effects and Ca(2+) signaling induced by endothelin-1 through crosstalk with norepinephrine in canine ventricular myocardium. (2005) (3)
- CHAPTER 35 – Cardiac Action of Angiotensin II (2001) (3)
- alpha-Adrenoceptors in the ventricular myocardium: clonidine, naphazoline and methoxamine as partial alpha-agonists exerting a competitive dualism in action to phenylephrine. (1976) (3)
- α-adrenoceptors mediating the positive inotropic effect of phenylephrine in the right ventricular muscle of the monkey (Macaca fuscata) (1982) (3)
- The large part German medicine has played in the development of experimental pharmacology in Japan (2022) (3)
- Influence of the acute stress on agonist-stimulated phosphoinositide hydrolysis in the rat cerebral cortex. (1992) (3)
- Preponderance of β- over α-adrenoceptors in mediating the positive inotropic effect of phenylephrine in the ferret ventricular myocardium (1989) (3)
- Modulation by aging of the coronary vascular response to endothelin-1 in the rat isolated perfused heart (1993) (3)
- Modulation of Myocardial Contractility by Taurine: Absence of its Interactions with the Effects of Low [CA2+]0, Verapamil, Bay K 8644, and α - and β-Adrenoceptor Agonists in the Rabbit Papillary Muscle (1989) (3)
- Contributions Myocardial a 1-Adrenoceptors Mediate Positive Inotropic Effect and Changes in Phosphatidylinositol Metabolism Species Differences in Receptor Distribution and the Intracellular Coupling Process in Mammalian Ventricular Myocardium (2005) (2)
- Differential inhibition by TAK-044 of the inotropic effects of endothelin-1 and endothelin-3. (2004) (2)
- Ca2+ Transients, Contractility, and Inotropic Responses in Rabbit Volume-Overloaded Cardiomyocytes (2000) (2)
- Myocardial alpha 1A-adrenoceptor subtypes in rabbit: differentiation by a selective antagonist, HV723. (1993) (2)
- Stress Vulnerability Induced by Neonatal Isolation and the Disturbance Between the Phosphorylation and Dephosphorylation of CREB (2006) (2)
- Noradrenergic Function and the Dexamethasone Suppression Test in Depression (1987) (2)
- Physiological and pathophysiological modulation of calcium signaling in myocardial cells. (1991) (2)
- Pharmacological characteristics of endothelin receptors in the rabbit ventricular myocardium: The nonselective endothelin receptor antagonist PD 145065 antagonizes the positive inotropic effect of endothelin-3 but not of endothelin-1 (1996) (2)
- Subcellular mechanism of desensitization of the ATP-induced Ca2+ mobilization in human umbilical vein endothelial cells: role of intracellular Ca2+ stores. (1991) (2)
- Relationship between the level of cAMP and the contractile force under stimulation of alpha- and beta-adrenoceptors by phenylephrine in the isolated rabbit papillary muscle. (1976) (2)
- Subcellular mechanism of the positive inotropic effect of a new quinolinone derivative OPC-8490 on the dog ventricular myocardium (2005) (2)
- Role of neuronal components in the high K-induced changes in calcium transients in the aequorin-loaded ferret portal vein (1990) (2)
- COMMENTARY Could Ca 2 þ sensitizers rescue patients from chronic congestive heart failure (2007) (2)
- The preferential inhibition of alpha 1- over beta-adrenoceptor-mediated positive inotropic effect by organic calcium antagonists in the rabbit papillary muscle. (1990) (2)
- Pharmacological characteristics of inhibitory action of the selective alpha1-antagonist JTH-601 on the positive inotropic effect mediated by alpha1-adrenoceptors in isolated rabbit papillary muscle. (2000) (1)
- Localization of pheochromocytoma by measurement of plasma cyclic AMP. (1984) (1)
- Differential effects of 8-bromo-cyclic GMP on the basal contractile force and beta-adrenoceptor-mediated positive inotropic action in the canine atrium. (1983) (1)
- Effect of (+)-niguldipine on myocardial alpha 1-adrenoceptors in the rabbit. (1992) (1)
- [Intracellular Ca2+ mobilization in cardiac muscle]. (1988) (1)
- Chronic dexamethasone administration decreases noradrenaline-stimulated, but not serotonin-stimulated, phosphoinositide metabolism in the rat brain (1996) (1)
- Negative inotropic effect mediated by adenosine receptors in the ferret ventricular myocardium (1990) (1)
- Wortmannin inhibits the increase in myofilament Ca(2+) sensitivity induced by cross-talk of endothelin-1 with norepinephrine in canine ventricular myocardium. (2009) (1)
- 42 – INTERACTION BETWEEN CYCLIC AMP AND CYCLIC GMP IN THE CONTRACTILITY OF DOG VENTRICULAR MYOCARDIUM (1978) (1)
- Two Calcium Compartments in Vascular Smooth Muscle (1996) (1)
- Circulation Research Editors’ Yearly Report: 2001 (2002) (1)
- Ca^ Sensitizers and Congestive Heart Failure(The 71st Annual Scientific Meeting of the Japanese Circulation Society) (2007) (1)
- Heart Failure: Management and Prevention of Heart Failure Based on Current Understanding of Pathophysiological Mechanisms (2014) (1)
- Effects of a new 1,3-thiazole Derivative ZSY-39 on force of contraction and cyclic AMP content in canine ventricular muscle (1990) (1)
- Novel signalling cascade for cardiac hypertrophy activation by uncoupling and internalization of beta1-adrenoceptors. (2008) (1)
- Involvement of phosphoinositide metabolism in the positive inotropic effect of angiotensin II (1992) (1)
- CA2+ SIGNALING IN REGULATION OF MYOCARDIAL CONTRACTILITY : MECHANISMS FOR REGULATION OF CARDIAC PERFORMANCE AND THE ACTION OF CARDIOTONIC AGENTS (1997) (1)
- IUPHAR 2006--15th World Congress of Pharmacology. Pharmacology in the 21st Century: a bridge between the past and the new molecular frontiers. 2-7 July 2006, Beijing, China. (2006) (1)
- [Magnesium and cardiovasvular regulatory factor]. (2005) (1)
- [Characteristics of alpha-adrenoceptors in the rabbit ventricular myocardium]. (1987) (0)
- [Regulation of myocardial contractility by catecholamines]. (1989) (0)
- Effects of Ro 20-1724, a selective inhibitor of cGMP-insensitive type IV phosphodiesterase, on the contractile force and isoproterenol-induced positive inotropic effect in the isolated rabbit papillary muscle (1990) (0)
- Are there perspectives for better intropic interventions in heart failure (2002) (0)
- Preponderance of beta- over alpha-adrenoceptors in mediating the positive inotropic effect of phenylephrine in the ferret ventricular myocardium. (1989) (0)
- Endothelin-induced phosphoinositide hydrolysis and positive inotropic effect in the rabbit ventricular papillary muscle. (1991) (0)
- P-43 Inotropic effects of growth hormone-releasing peptide-2: Cross-talk with catecholamine (2002) (0)
- [Altered regulation of cardiac contraction and relaxation by Ca2+ in heart failure]. (2001) (0)
- Between Endothelin-1 and Norepinephrine in Dog Ventricular Myocardium Signaling in Contractile Regulation Induced by Crosstalk 2 + Signal Transduction (2003) (0)
- Meet Our Editorial Board Member (2018) (0)
- [Ca2+ signaling in cardiac E-C coupling and its modulation in cardiac hypertrophy and heart failure]. (1998) (0)
- SUBCELLULAR MECHANISMS UNDERLYING THE INHIBITORY ACTION OF MUSCARINIC CHOLINERGIC RECEPTOR AGONISTS ON MAMMALIAN MYOCARDIAL CONTRACTILITY IN RELATION TO CHANGES IN INTRACELLULAR CALCIUM TRANSIENTS (1991) (0)
- Mechanisms of Action (2002) (0)
- SERCA in heterogeneity of diastolic dysfunction in post-infarction heart failure with reduced ejection fraction. (2019) (0)
- Myocardial alpha-1-adrenoceptor sub-types mediating positive inotropic effect of methoxamine in rabbit ventricular muscle. (1993) (0)
- Modification by islet activating protein of adrenergic cholinergic interaction on the rate and force of isolated rat heart preparations (1981) (0)
- Mechanisms and Pharmacological Classification of Ca 2 + Sensitizers (2011) (0)
- Characteristics of cardiotonic effect of ET-1 in rabbit heart. (1993) (0)
- Cloning of a Kvβ subunit from a rabbit heart cDNA library (1998) (0)
- Different mechanisms responsible for the inhibitory action of endothelins on the chronotropic and inotropic responses to β-adrenergic stimulation. (1996) (0)
- P-42 The role of Na+/H+ exchange in the angiotesin II induced negative inotropic effect in indo-1 loaded adult mouse ventricular myocytes (2002) (0)
- Regulation of calcium transients by activation of P2-purinergic receptors in human endothelial cells in culture (1990) (0)
- Differential regulation by ET-1 of L-type Ca2+ current in rabbit and dog ventricular cardiomyocytes (1999) (0)
- Light Transients in Intact Canine Ventricular Myocardium (2005) (0)
- [Adenosine and muscarinic receptors in regulation of myocardial contractility: dual mechanism of inhibitory action]. (1987) (0)
- Regulation of force and intracellular calcium transients by cyclic AMP generated by forskolin, MDL 17,043 and isoprenaline, and its modulation by muscarinic receptor agents: a novel mechanism for accentuated antagonism (2007) (0)
- Role of GTP-binding proteins in muscarinic and adenosine receptor-mediaton inhibitory regulation of cardiac function (1987) (0)
- Absence of inhibitory action of carbachol on the positive inotropic effect of phenylephrine and methoxamine mediated via α-adrenoceptor stimulation in the isolated rabbit papillary muscle (1979) (0)
- Selective inhibition by staurosporin of the positive inotropic effect of phenylephrine mediated by ∝-adrenoceptors in the isolated rabbit papillary muscle (1990) (0)
- Kffects of vasopressin on phosphoinositide hydrolysis and force of contraction in the isolated rabbit ventricular myocardium (1992) (0)
- [Signal transduction in regulation of myocardial contractility]. (1993) (0)
- Cardiotonic Agents: Mechanisms and Characteristics of Action (2007) (0)
- Characterization of the angiotensin II - induced Cl- current in the rabbit ventricular myocytes. (1994) (0)
- Subcellular mechanism of the positive inotropic effect of a new cardiotonic agent Org 9731 on the dog ventricular myocardium. (1993) (0)
- Effects of SCH00013, a novel cardiotonic agent, on membrane currents in rabbit and dog vetricular cardiomyocytes (2000) (0)
- Influence of cyclopiazonic acid and ryanodine on the increase in force and cytosolic Ca2+ concentration induced by noradrenaline in ferret portal vein loaded with aequorin. (1994) (0)
- [Ca2+ sensitizers]. (2000) (0)
- S1-1 Frequency-dependent block of HERG mutant channels by methanesulfonanilides (2002) (0)
- Levosimendan of its Use in the Management of Acute Decompensated Heart Failure (2003) (0)
- 14th World Congress of Endoscopic Surgery and 22nd International Congress of the European Association for Endoscopic Surgery (EAES), Paris, France, 25–28 June 2014 (2015) (0)
- Cardiac effects of a new cardiotonic drug, AR-L 115 BS. (1983) (0)
- Influence of acidosis on the positive inotropic effect of OR-1896, an active metabolite levosimendan, in intact canine ventricular myocardium (2001) (0)
- IUTOX: International Congress of Toxicology-VII (Seattle, USA, July 2-6, 1995) [第7回国際毒科学会議] (1995) (0)
- The XV World congress of the International Society Heart Research (Prague, Czech Republic, July 2-7, 1995) (1995) (0)
- A unique positive inotropic agent Org 30029 acts by increase in calcium sensitivity of contractile proteins in the intact dog ventricular myocardium (1992) (0)
- [Recent advances in research on cardiovascular drug receptors]. (1993) (0)
- The 2nd International Meeting on Endothelial Control of Cardiac Performance (Antwerp, Belgium, June 28-30, 1995)[内皮性心機能調節に関する第2回国際シンポジウム] (1995) (0)
- Proceedings: Effects of isoprenaline and methoxamine on contractile force and on the cyclic 3', 5'-AMP level in the isolated rabbit papillary muscle. (1975) (0)
- Differential antagonistic action of tamsulosin on the positive inotropic effect and the acceleration of phosphoinositide (PI) hydrolysis mediated by alpha1-adrenoceptors in rabbit ventricular muscle (1995) (0)
- [Mechanism of positive inotropic action of catecholamines]. (1983) (0)
- Cyclic AMP and cyclic GMP in the mechanical responses of the mammalian ventricular myocardium to adrenoceptor and muscarinic cholinergic receptor stimulation. (1980) (0)
- Effects of papaverine on the contractile force and intracellular cyclic AMP level of the isolated canine ventricular myocardium (1978) (0)
- Short Communication Stimulation by Phenylephrine of Adrenergic Alpha- and Beta-Receptors in the Isolated Perfused Rabbit Heart (1974) (0)
- Involvement of diacylglycerol/protein kinase C pathway in endothelin-1-induced negative inotropic effect in mouse ventricular myocytes (2006) (0)
- Differential modulation induced by acidosis of eeffects of Ca2+ sensitizers in intact canine ventricular myocardium (2001) (0)
- EFFECTS ON THE VENTRICULAR MYOCARDIUM: SOME ASPECTS OF STRUCTURE-ACTIVITY RELATIONSHIP OF SYMPATHOMIMETIC (2006) (0)
- Sensitivity , Intracellular Ca 2 + Mobilization , Signaling Pathway , and Pathophysiological Relevance (2016) (0)
- [Molecular mechanism of heart conduction system]. (2002) (0)
- [Cav channels and Ca2+ antagonists: recent advances in molecular characteristics and pharmacology]. (2006) (0)
- Mechanisms of action of Ca2+ sensitizer Org 30029: effects on the contractile depression induced by acidosis and 2, 3-butanedione monoxime. (1995) (0)
- Pharmacological characteristics of adenosine-induced inhibitory action in ferret ventricular myocardium (1990) (0)
- INTRACELLULAR CALCIUM MOBILIZATION AND ITS MODULATION BY PHYSIOLOGICAL AND PATHOPHYSIOLOGICAL INTERVENTIONS IN AEQUORIN-INJECTED MYOCARDIAL CELLS (1989) (0)
- α1-Adrenergic receptor-dependent regulation of myocardial contractility (1996) (0)
- Under new management: A six-month progress report on Circulation Research. (2000) (0)
- EFFECTS OF ANTIARRHYTHMIC DRUGS ON THE CURRENTS OF XENOPUS OOCYTES EXPRESSING HERG AND KvLQT1/minK CHANNELS (2005) (0)
- Herg point mutants that affect methanesulfonanilides binding (1999) (0)
- Differential Inhibition by the Phosphatase Inhibitor Cantharidin of the Anti-adrenergic Effect of Endothelin-1 and Carbachol in the Canine Ventricular Myocardium (2004) (0)
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What Schools Are Affiliated With Masao Endoh?
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