Masayuki Yamamoto
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Researcher ORCID ID = 0000-0002-9073-9436
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Philosophy Biology
Masayuki Yamamoto's Degrees
- PhD Biochemistry University of Tokyo
- Doctorate Medicine University of Tokyo
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(Suggest an Edit or Addition)Masayuki Yamamoto's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements. (1997) (3591)
- Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain. (1999) (3144)
- Homeostatic Levels of p62 Control Cytoplasmic Inclusion Body Formation in Autophagy-Deficient Mice (2007) (2045)
- Oxidative Stress Sensor Keap1 Functions as an Adaptor for Cul3-Based E3 Ligase To Regulate Proteasomal Degradation of Nrf2 (2004) (1881)
- The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1 (2010) (1870)
- Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants (2002) (1801)
- A promoter-level mammalian expression atlas (2014) (1664)
- Nrf2-Keap1 defines a physiologically important stress response mechanism. (2004) (1556)
- Molecular mechanisms of the Keap1–Nrf2 pathway in stress response and cancer evolution (2011) (1237)
- Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray. (2002) (1178)
- Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice (2001) (1133)
- Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming. (2012) (1089)
- Keap1-dependent Proteasomal Degradation of Transcription Factor Nrf2 Contributes to the Negative Regulation of Antioxidant Response Element-driven Gene Expression* (2003) (1012)
- Molecular mechanisms activating the Nrf2-Keap1 pathway of antioxidant gene regulation. (2005) (1001)
- Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription (2016) (1001)
- Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice. (2004) (959)
- Protection against electrophile and oxidant stress by induction of the phase 2 response: Fate of cysteines of the Keap1 sensor modified by inducers (2004) (939)
- Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis. (2006) (919)
- Phosphorylation of p62 activates the Keap1-Nrf2 pathway during selective autophagy. (2013) (797)
- Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation (2003) (793)
- Molecular mechanism activating Nrf2-Keap1 pathway in regulation of adaptive response to electrophiles. (2004) (789)
- The KEAP1-NRF2 System: a Thiol-Based Sensor-Effector Apparatus for Maintaining Redox Homeostasis. (2018) (789)
- Oxidative and Electrophilic Stresses Activate Nrf2 through Inhibition of Ubiquitination Activity of Keap1 (2006) (788)
- Keap1 regulates both cytoplasmic‐nuclear shuttling and degradation of Nrf2 in response to electrophiles (2003) (774)
- Nrf2-Keap1 regulation of cellular defense mechanisms against electrophiles and reactive oxygen species. (2006) (768)
- High sensitivity of Nrf2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated drug metabolizing enzymes and antioxidant genes. (2001) (716)
- Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy (2008) (674)
- Molecular basis of the Keap1-Nrf2 system. (2015) (672)
- Role of NRF2 in protection against hyperoxic lung injury in mice. (2002) (668)
- The Cap'n'Collar basic leucine zipper transcription factor Nrf2 (NF-E2 p45-related factor 2) controls both constitutive and inducible expression of intestinal detoxification and glutathione biosynthetic enzymes. (2001) (667)
- Structural basis for defects of Keap1 activity provoked by its point mutations in lung cancer. (2006) (659)
- Reactive cysteine persulfides and S-polythiolation regulate oxidative stress and redox signaling (2014) (625)
- Keap1 Recruits Neh2 through Binding to ETGE and DLG Motifs: Characterization of the Two-Site Molecular Recognition Model (2006) (617)
- Bach proteins belong to a novel family of BTB-basic leucine zipper transcription factors that interact with MafK and regulate transcription through the NF-E2 site (1996) (612)
- Disruption of Nrf2 enhances susceptibility to severe airway inflammation and asthma in mice (2005) (586)
- Hemoprotein Bach1 regulates enhancer availability of heme oxygenase‐1 gene (2002) (575)
- Activity and tissue-specific expression of the transcription factor NF-E1 multigene family. (1990) (574)
- Loss of Keap1 function activates Nrf2 and provides advantages for lung cancer cell growth. (2008) (566)
- The Antioxidant Defense System Keap1-Nrf2 Comprises a Multiple Sensing Mechanism for Responding to a Wide Range of Chemical Compounds (2008) (566)
- Toward clinical application of the Keap1-Nrf2 pathway. (2013) (555)
- Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells (2011) (527)
- Enhanced Expression of the Transcription Factor Nrf2 by Cancer Chemopreventive Agents: Role of Antioxidant Response Element-Like Sequences in the nrf2 Promoter (2002) (527)
- Scaffolding of Keap1 to the actin cytoskeleton controls the function of Nrf2 as key regulator of cytoprotective phase 2 genes (2004) (499)
- Modulation of Gene Expression by Cancer Chemopreventive Dithiolethiones through the Keap1-Nrf2 Pathway (2003) (481)
- Physiological Significance of Reactive Cysteine Residues of Keap1 in Determining Nrf2 Activity (2008) (473)
- Identification of a novel Nrf2-regulated antioxidant response element (ARE) in the mouse NAD(P)H:quinone oxidoreductase 1 gene: reassessment of the ARE consensus sequence. (2003) (471)
- Dimerization of Substrate Adaptors Can Facilitate Cullin-mediated Ubiquitylation of Proteins by a “Tethering” Mechanism (2006) (458)
- Antioxidants Enhance Mammalian Proteasome Expression through the Keap1-Nrf2 Signaling Pathway (2003) (456)
- Discovery of the negative regulator of Nrf2, Keap1: a historical overview. (2010) (451)
- Electrophile Response Element-mediated Induction of the Cystine/Glutamate Exchange Transporter Gene Expression* (2002) (450)
- MafA Is a Key Regulator of Glucose-Stimulated Insulin Secretion (2005) (449)
- Genetic alteration of Keap1 confers constitutive Nrf2 activation and resistance to chemotherapy in gallbladder cancer. (2008) (445)
- Two-site substrate recognition model for the Keap1-Nrf2 system: a hinge and latch mechanism (2006) (445)
- Integration and diversity of the regulatory network composed of Maf and CNC families of transcription factors. (2002) (439)
- The Transcription Factor Nrf2 Is a Therapeutic Target against Brain Inflammation1 (2008) (430)
- Regulation of transcription by dimerization of erythroid factor NF-E2 p45 with small Maf proteins (1994) (419)
- Fumarates Promote Cytoprotection of Central Nervous System Cells against Oxidative Stress via the Nuclear Factor (Erythroid-Derived 2)-Like 2 Pathway (2012) (410)
- Cloning and characterization of a novel erythroid cell-derived CNC family transcription factor heterodimerizing with the small Maf family proteins (1995) (402)
- Loss of the Nrf2 transcription factor causes a marked reduction in constitutive and inducible expression of the glutathione S-transferase Gsta1, Gsta2, Gstm1, Gstm2, Gstm3 and Gstm4 genes in the livers of male and female mice. (2002) (402)
- GATA1 Function, a Paradigm for Transcription Factors in Hematopoiesis (2005) (401)
- Role of Nrf2 in the Regulation of CD36 and Stress Protein Expression in Murine Macrophages: Activation by Oxidatively Modified LDL and 4-Hydroxynonenal (2004) (392)
- Keap1 degradation by autophagy for the maintenance of redox homeostasis (2012) (383)
- Nrf2 Enhances Cell Proliferation and Resistance to Anticancer Drugs in Human Lung Cancer (2009) (373)
- Hepatocyte-specific deletion of the keap1 gene activates Nrf2 and confers potent resistance against acute drug toxicity. (2006) (365)
- Redox-regulated Turnover of Nrf2 Is Determined by at Least Two Separate Protein Domains, the Redox-sensitive Neh2 Degron and the Redox-insensitive Neh6 Degron* (2004) (363)
- Different Electrostatic Potentials Define ETGE and DLG Motifs as Hinge and Latch in Oxidative Stress Response (2007) (363)
- Carnosic acid, a catechol‐type electrophilic compound, protects neurons both in vitro and in vivo through activation of the Keap1/Nrf2 pathway via S‐alkylation of targeted cysteines on Keap1 (2008) (355)
- Transcription Factor Nrf2 Regulates Inflammation by Mediating the Effect of 15-Deoxy-Δ12,14-Prostaglandin J2 (2004) (352)
- Role of Nrf2 signaling in regulation of antioxidants and phase 2 enzymes in cardiac fibroblasts: Protection against reactive oxygen and nitrogen species‐induced cell injury (2005) (351)
- Nrf2-deficient female mice develop lupus-like autoimmune nephritis. (2001) (348)
- The transcription factor NRF2 protects against pulmonary fibrosis (2004) (344)
- Functional polymorphisms in the transcription factor NRF2 in humans increase the risk of acute lung injury (2007) (343)
- Nrf2 Is Essential for the Chemopreventive Efficacy of Oltipraz against Urinary Bladder Carcinogenesis (2004) (342)
- Nrf2 impacts cellular bioenergetics by controlling substrate availability for mitochondrial respiration (2013) (341)
- Targeting Nrf2 with the triterpenoid CDDO- imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice (2009) (340)
- The Keap1–Nrf2 system in cancers: stress response and anabolic metabolism (2012) (335)
- Rare variant discovery by deep whole-genome sequencing of 1,070 Japanese individuals (2015) (334)
- The Nrf2 transcription factor contributes both to the basal expression of glutathione S-transferases in mouse liver and to their induction by the chemopreventive synthetic antioxidants, butylated hydroxyanisole and ethoxyquin. (2000) (332)
- Nrf2-dependent protection from LPS induced inflammatory response and mortality by CDDO-Imidazolide. (2006) (328)
- Regulatory mechanisms of cellular response to oxidative stress. (1999) (327)
- Nrf2‐deficient mice are highly susceptible to cigarette smoke‐induced emphysema (2005) (325)
- Murine and human T-lymphocyte GATA-3 factors mediate transcription through a cis-regulatory element within the human T-cell receptor delta gene enhancer (1991) (318)
- Identification of the interactive interface and phylogenic conservation of the Nrf2‐Keap1 system (2002) (315)
- Genome-wide association study identifies 112 new loci for body mass index in the Japanese population (2017) (314)
- The Molecular Mechanisms Regulating the KEAP1-NRF2 Pathway (2020) (314)
- Oxidative and electrophilic stress induces multidrug resistance–associated protein transporters via the nuclear factor‐E2–related factor‐2 transcriptional pathway (2007) (312)
- Nrf2–MafG heterodimers contribute globally to antioxidant and metabolic networks (2012) (312)
- Nrf2 regulates microglial dynamics and neuroinflammation in experimental Parkinson's disease (2010) (310)
- The KEAP1–NRF2 System in Cancer (2017) (304)
- Erythroid transcription factor GATA-1 is abundantly transcribed in mouse testis (1993) (300)
- Small Maf proteins serve as transcriptional cofactors for keratinocyte differentiation in the Keap1-Nrf2 regulatory pathway. (2004) (300)
- NRF2 Modulates Aryl Hydrocarbon Receptor Signaling: Influence on Adipogenesis (2007) (299)
- Dysfunction of fibroblasts of extrarenal origin underlies renal fibrosis and renal anemia in mice. (2011) (299)
- Nrf1 and Nrf2 Play Distinct Roles in Activation of Antioxidant Response Element-dependent Genes* (2008) (288)
- The world according to Maf. (1997) (278)
- Pharmacodynamic characterization of chemopreventive triterpenoids as exceptionally potent inducers of Nrf2-regulated genes (2006) (273)
- Transcription factor NFE2L2/NRF2 is a regulator of macroautophagy genes (2016) (272)
- Transcription factor Nrf2 is required for the constitutive and inducible expression of multidrug resistance-associated protein 1 in mouse embryo fibroblasts. (2003) (270)
- The transcriptional programme of antibody class switching involves the repressor Bach2 (2004) (268)
- Stress-sensing mechanisms and the physiological roles of the Keap1–Nrf2 system during cellular stress (2017) (263)
- Neurogenin3 delineates the earliest stages of spermatogenesis in the mouse testis. (2004) (261)
- Nrf2 is essential for cholesterol crystal‐induced inflammasome activation and exacerbation of atherosclerosis (2011) (259)
- A Sulforaphane Analogue That Potently Activates the Nrf2-dependent Detoxification Pathway* (2002) (259)
- The Keap1-Nrf2 System Prevents Onset of Diabetes Mellitus (2013) (255)
- Genetic versus chemoprotective activation of Nrf2 signaling: overlapping yet distinct gene expression profiles between Keap1 knockout and triterpenoid-treated mice. (2009) (253)
- Role of phase 2 enzyme induction in chemoprotection by dithiolethiones. (2001) (251)
- Developmental stage- and spermatogenic cycle-specific expression of transcription factor GATA-1 in mouse Sertoli cells. (1994) (248)
- Role of Nrf2 in prevention of high-fat diet-induced obesity by synthetic triterpenoid CDDO-imidazolide. (2009) (246)
- Transcription factor Nrf2 is protective during ischemic and nephrotoxic acute kidney injury in mice. (2009) (246)
- Gene expression profiling of NRF2-mediated protection against oxidative injury. (2005) (245)
- Regulation of Lens Fiber Cell Differentiation by Transcription Factor c-Maf* (1999) (241)
- Genetic Evidence that Small Maf Proteins Are Essential for the Activation of Antioxidant Response Element-Dependent Genes (2005) (238)
- Intrinsic Function of the Aryl Hydrocarbon (Dioxin) Receptor as a Key Factor in Female Reproduction (2005) (238)
- The transcription factor FoxH1 (FAST) mediates Nodal signaling during anterior-posterior patterning and node formation in the mouse. (2001) (235)
- Mouse Spermatogenic Stem Cells Continually Interconvert between Equipotent Singly Isolated and Syncytial States (2014) (234)
- Hydrogen sulfide anion regulates redox signaling via electrophile sulfhydration. (2012) (234)
- p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming (2016) (234)
- Role of Transcription Factor Nrf2 in the Induction of Hepatic Phase 2 and Antioxidative Enzymes in vivo by the Cancer Chemoprotective Agent, 3H-1, 2-Dithiole-3-thione (2001) (234)
- HLF/HIF‐2α is a key factor in retinopathy of prematurity in association with erythropoietin (2003) (232)
- Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation. (2012) (232)
- A cross-population atlas of genetic associations for 220 human phenotypes (2021) (229)
- Transcription Factor Nrf2 Plays a Pivotal Role in Protection against Elastase-Induced Pulmonary Inflammation and Emphysema1 (2005) (229)
- Expression of vascular permeability factor/vascular endothelial growth factor in human hepatocellular carcinoma. (1996) (227)
- Validation of the multiple sensor mechanism of the Keap1-Nrf2 system. (2012) (226)
- Nrf2 Protects Against Maladaptive Cardiac Responses to Hemodynamic Stress (2009) (225)
- Unique function of the Nrf2-Keap1 pathway in the inducible expression of antioxidant and detoxifying enzymes. (2004) (224)
- A Comprehensive Genomic Analysis Reveals the Genetic Landscape of Mitochondrial Respiratory Chain Complex Deficiencies (2016) (221)
- Nuclear factor erythroid 2-related factor 2 protects against beta amyloid (2008) (220)
- Differential Responses of the Nrf2-Keap1 System to Laminar and Oscillatory Shear Stresses in Endothelial Cells* (2005) (220)
- Nrf2 mediates cancer protection but not prolongevity induced by caloric restriction (2008) (217)
- Glutathione peroxidase 2, the major cigarette smoke-inducible isoform of GPX in lungs, is regulated by Nrf2. (2006) (216)
- The rise of antioxidant signaling--the evolution and hormetic actions of Nrf2. (2010) (213)
- Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor (1995) (213)
- The circadian clock regulates rhythmic activation of the NRF2/glutathione-mediated antioxidant defense pathway to modulate pulmonary fibrosis (2014) (210)
- Nrf2 prevents initiation but accelerates progression through the Kras signaling pathway during lung carcinogenesis. (2013) (210)
- Evolutionary conserved N-terminal domain of Nrf2 is essential for the Keap1-mediated degradation of the protein by proteasome. (2005) (206)
- Essential and Instructive Roles of GATA Factors in Eosinophil Development (2002) (206)
- Transcription factor Nrf2 is essential for induction of NAD(P)H:quinone oxidoreductase 1, glutathione S-transferases, and glutamate cysteine ligase by broccoli seeds and isothiocyanates. (2004) (204)
- Important Role of Endogenous Erythropoietin System in Recruitment of Endothelial Progenitor Cells in Hypoxia-Induced Pulmonary Hypertension in Mice (2006) (204)
- Krüppel-like factor 5 is essential for blastocyst development and the normal self-renewal of mouse ESCs. (2008) (203)
- Protein S-guanylation by the biological signal 8-nitroguanosine 3',5'-cyclic monophosphate. (2007) (203)
- Erythroid-specific expression of the erythropoietin receptor rescued its null mutant mice from lethality. (2002) (201)
- Keap1 is a forked-stem dimer structure with two large spheres enclosing the intervening, double glycine repeat, and C-terminal domains (2010) (200)
- Frequent mutations in the GATA-1 gene in the transient myeloproliferative disorder of Down syndrome. (2003) (199)
- Regulation of Notch1 Signaling by Nrf2: Implications for Tissue Regeneration (2010) (198)
- Role of Nrf2 in protection against intracerebral hemorrhage injury in mice. (2007) (195)
- Identification of Bach2 as a B‐cell‐specific partner for small Maf proteins that negatively regulate the immunoglobulin heavy chain gene 3′ enhancer (1998) (195)
- Roles of Hematopoietic Transcription Factors GATA-1 and GATA-2 in the Development of Red Blood Cell Lineage (2002) (194)
- Hyperglycemia induces oxidative and nitrosative stress and increases renal functional impairment in Nrf2‐deficient mice (2008) (194)
- Genetic Analysis of Cytoprotective Functions Supported by Graded Expression of Keap1 (2010) (193)
- NRF2 mutation confers malignant potential and resistance to chemoradiation therapy in advanced esophageal squamous cancer. (2011) (192)
- Repression via the GATA box is essential for tissue-specific erythropoietin gene expression. (2008) (191)
- MafB Is Essential for Renal Development and F4/80 Expression in Macrophages (2006) (191)
- Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases (2020) (191)
- Increased colonic inflammatory injury and formation of aberrant crypt foci in Nrf2‐deficient mice upon dextran sulfate treatment (2007) (189)
- Characterizations of Three Major Cysteine Sensors of Keap1 in Stress Response (2015) (189)
- Arrest in Primitive Erythroid Cell Development Caused by Promoter-specific Disruption of the GATA-1 Gene* (1997) (189)
- The aryl hydrocarbon receptor AhR links atopic dermatitis and air pollution via induction of the neurotrophic factor artemin (2016) (186)
- Activation of hepatic Nrf2 in vivo by acetaminophen in CD‐1 mice (2004) (185)
- Transcription factor Nrf2 regulates inflammation by mediating the effect of 15-deoxy-Delta(12,14)-prostaglandin j(2). (2004) (184)
- Interactive effects of nrf2 genotype and oltipraz on benzo[a]pyrene-DNA adducts and tumor yield in mice. (2003) (183)
- Establishment and characterization of an erythropoietin-dependent subline, UT-7/Epo, derived from human leukemia cell line, UT-7. (1993) (181)
- Accumulation of p62/SQSTM1 is associated with poor prognosis in patients with lung adenocarcinoma (2012) (179)
- The Flavanol (−)-Epicatechin Prevents Stroke Damage through the Nrf2/HO1 Pathway (2010) (176)
- Nrf2-deficiency creates a responsive microenvironment for metastasis to the lung. (2010) (175)
- GATA-1 transcription is controlled by distinct regulatory mechanisms during primitive and definitive erythropoiesis. (1997) (175)
- Electrophilic Nitro-fatty Acids Activate NRF2 by a KEAP1 Cysteine 151-independent Mechanism* (2011) (175)
- Kinetic, Thermodynamic, and Structural Characterizations of the Association between Nrf2-DLGex Degron and Keap1 (2013) (174)
- BRG1 Interacts with Nrf2 To Selectively Mediate HO-1 Induction in Response to Oxidative Stress (2006) (174)
- A remote GATA2 hematopoietic enhancer drives leukemogenesis in inv(3)(q21;q26) by activating EVI1 expression. (2014) (170)
- BRL 49653 blocks the lipolytic actions of tumor necrosis factor-alpha: a potential new insulin-sensitizing mechanism for thiazolidinediones. (1998) (170)
- DNA methyltransferase 3a regulates osteoclast differentiation by coupling to an S-adenosylmethionine–producing metabolic pathway (2015) (169)
- The Keap1-Nrf2 system and diabetes mellitus. (2015) (168)
- Ubiquitin accumulation in autophagy-deficient mice is dependent on the Nrf2-mediated stress response pathway: a potential role for protein aggregation in autophagic substrate selection (2010) (168)
- Nrf2 Protects Pancreatic β-Cells From Oxidative and Nitrosative Stress in Diabetic Model Mice (2014) (164)
- Nuclear factor-eythroid 2-related factor 2 prevents alcohol-induced fulminant liver injury. (2008) (164)
- Roles of Nrf2 in activation of antioxidant enzyme genes via antioxidant responsive elements. (2002) (164)
- Antiviral activity of Nrf2 in a murine model of respiratory syncytial virus disease. (2009) (161)
- Transcription factor Nrf2 mediates an adaptive response to sulforaphane that protects fibroblasts in vitro against the cytotoxic effects of electrophiles, peroxides and redox-cycling agents. (2009) (160)
- Shear stress stabilizes NF-E2-related factor 2 and induces antioxidant genes in endothelial cells: role of reactive oxygen/nitrogen species. (2007) (160)
- Disruption of Nrf2 Impairs the Resolution of Hyperoxia-Induced Acute Lung Injury and Inflammation in Mice1 (2009) (158)
- Constitutive Expression of Aryl Hydrocarbon Receptor in Keratinocytes Causes Inflammatory Skin Lesions (2005) (158)
- Distinct response to dioxin in an arylhydrocarbon receptor (AHR)-humanized mouse (2003) (157)
- Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology (2022) (157)
- Ultraviolet A irradiation induces NF-E2-related factor 2 activation in dermal fibroblasts: protective role in UVA-induced apoptosis. (2005) (155)
- A Novel Type of E3 Ligase for the Ufm1 Conjugation System* (2009) (154)
- Small Maf proteins (MafF, MafG, MafK): History, structure and function. (2016) (153)
- FANTOM5 CAGE profiles of human and mouse samples (2017) (153)
- Increased Nrf2 activation in livers from Keap1-knockdown mice increases expression of cytoprotective genes that detoxify electrophiles more than those that detoxify reactive oxygen species. (2009) (151)
- Molecular mechanisms for the regulation of Nrf2-mediated cell proliferation in non-small-cell lung cancers (2012) (150)
- Proteomic analysis of Nrf2 deficient transgenic mice reveals cellular defence and lipid metabolism as primary Nrf2-dependent pathways in the liver (2010) (150)
- Mitochondrial SKN-1/Nrf mediates a conserved starvation response. (2012) (150)
- Nrf2 protects against pulmonary fibrosis by regulating the lung oxidant level and Th1/Th2 balance (2010) (147)
- Conditional Gata2 inactivation results in HSC loss and lymphatic mispatterning. (2012) (146)
- Targeting Nrf2-mediated gene transcription by extremely potent synthetic triterpenoids attenuate dopaminergic neurotoxicity in the MPTP mouse model of Parkinson's disease. (2013) (145)
- Positive or Negative MARE-Dependent Transcriptional Regulation Is Determined by the Abundance of Small Maf Proteins (2000) (145)
- Expression of delta-aminolevulinate synthase in avian cells: separate genes encode erythroid-specific and nonspecific isozymes. (1989) (144)
- Genetic or pharmacologic amplification of nrf2 signaling inhibits acute inflammatory liver injury in mice. (2008) (144)
- Metabolism and Tissue Distribution of Sulforaphane in Nrf2 Knockout and Wild-Type Mice (2011) (143)
- GATA2 is required for the generation of V2 interneurons. (2000) (142)
- Adipose Deficiency of Nrf2 in ob/ob Mice Results in Severe Metabolic Syndrome (2013) (142)
- Nrf2 regulates ferroportin 1-mediated iron efflux and counteracts lipopolysaccharide-induced ferroportin 1 mRNA suppression in macrophages. (2011) (141)
- Plasticity of renal erythropoietin-producing cells governs fibrosis. (2013) (141)
- Molecular Mechanism of Cellular Oxidative Stress Sensing by Keap1. (2019) (139)
- Ebselen, a seleno-organic antioxidant, as an electrophile. (2006) (139)
- Disruption of the Transcription Factor Nrf2 Promotes Pro-Oxidative Dendritic Cells That Stimulate Th2-Like Immunoresponsiveness upon Activation by Ambient Particulate Matter1 (2008) (138)
- Identification of polymorphisms in the promoter region of the human NRF2 gene. (2004) (133)
- Negative regulation of the erythropoietin gene expression by the GATA transcription factors. (1997) (133)
- NRF2 deficiency replicates transcriptomic changes in Alzheimer's patients and worsens APP and TAU pathology (2017) (133)
- The mouse GATA-2 gene is expressed in the para-aortic splanchnopleura and aorta-gonads and mesonephros region. (1999) (132)
- Nrf2 Regulates Antioxidant Gene Expression Evoked by Oxidized Phospholipids in Endothelial Cells and Murine Arteries In Vivo (2008) (129)
- Gut microbiome-derived phenyl sulfate contributes to albuminuria in diabetic kidney disease (2019) (129)
- Genetic disruption of the Nrf2 compromises cell-cycle progression by impairing GSH-induced redox signaling (2008) (129)
- Regulation of mouse mast cell protease 6 gene expression by transcription factor encoded by the mi locus. (1996) (129)
- The power of genetic diversity in genome-wide association studies of lipids (2021) (129)
- Role of transcription factor Nrf2 in the induction of hepatic phase 2 and antioxidative enzymes in vivo by the cancer chemoprotective agent, 3H-1, 2-dimethiole-3-thione. (2001) (128)
- Transcription factor Nrf2 hyperactivation in early-phase renal ischemia-reperfusion injury prevents tubular damage progression. (2017) (127)
- The Critical Role of Nitric Oxide Signaling, via Protein S-Guanylation and Nitrated Cyclic GMP, in the Antioxidant Adaptive Response* (2010) (126)
- Negative regulation of the Nrf1 transcription factor by its N-terminal domain is independent of Keap1: Nrf1, but not Nrf2, is targeted to the endoplasmic reticulum. (2006) (126)
- Wilms' tumor 1-associating protein regulates G2/M transition through stabilization of cyclin A2 mRNA (2006) (126)
- KEAP1-NRF2 complex in ischemia-induced hepatocellular damage of mouse liver transplants. (2013) (125)
- Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population (2019) (124)
- Nrf2-dependent sulfiredoxin-1 expression protects against cigarette smoke-induced oxidative stress in lungs. (2009) (124)
- Erythropoietin Synthesis in Renal Myofibroblasts Is Restored by Activation of Hypoxia Signaling. (2016) (123)
- Targeting the KEAP1-NRF2 System to Prevent Kidney Disease Progression (2017) (123)
- Cytoprotective role of Nrf2/Keap1 system in methylmercury toxicity. (2007) (123)
- Subcellular localization and cytoplasmic complex status of endogenous Keap1 (2007) (122)
- CD36 participates in a signaling pathway that regulates ROS formation in murine VSMCs. (2010) (121)
- Identification and characterization of 2 types of erythroid progenitors that express GATA-1 at distinct levels. (2003) (119)
- A Combinatorial Code for Gene Expression Generated by Transcription Factor Bach2 and MAZR (MAZ-Related Factor) through the BTB/POZ Domain (2000) (119)
- Human GATA-3 trans-activation, DNA-binding, and nuclear localization activities are organized into distinct structural domains (1994) (118)
- Genetic dissection of the Nrf2-dependent redox signaling-regulated transcriptional programs of cell proliferation and cytoprotection. (2007) (118)
- Hes repressors are essential regulators of hematopoietic stem cell development downstream of Notch signaling (2013) (117)
- Deletion of nuclear factor-E2-related factor-2 leads to rapid onset and progression of nutritional steatohepatitis in mice. (2010) (117)
- Nrf2 regulates the sensitivity of death receptor signals by affecting intracellular glutathione levels (2003) (116)
- Genipin, a metabolite derived from the herbal medicine Inchin-ko-to, and suppression of Fas-induced lethal liver apoptosis in mice. (2000) (116)
- Critical role of Nrf2 in oxidative stress‐induced retinal ganglion cell death (2011) (114)
- Role of 15-deoxy delta(12,14) prostaglandin J2 and Nrf2 pathways in protection against acute lung injury. (2005) (114)
- A Combination of HNF-4 and Foxo1 Is Required for Reciprocal Transcriptional Regulation of Glucokinase and Glucose-6-phosphatase Genes in Response to Fasting and Feeding* (2008) (114)
- Induction of cancer chemopreventive enzymes by coffee is mediated by transcription factor Nrf2. Evidence that the coffee-specific diterpenes cafestol and kahweol confer protection against acrolein. (2008) (113)
- Identification of six new genetic loci associated with atrial fibrillation in the Japanese population (2017) (113)
- Enhanced erythropoiesis mediated by activation of the renin‐angiotensin system via angiotensin II type 1a receptor (2005) (113)
- A Novel Class of Prolyl Hydroxylase Inhibitors Induces Angiogenesis and Exerts Organ Protection Against Ischemia (2007) (113)
- The Ufm1-activating enzyme Uba5 is indispensable for erythroid differentiation in mice (2011) (112)
- Expression and domain-specific function of GATA-2 during differentiation of the hematopoietic precursor cells in midgestation mouse embryos. (2003) (112)
- Nuclear factor erythroid-derived factor 2-related factor 2 regulates transcription of CCAAT/enhancer-binding protein β during adipogenesis. (2012) (112)
- Combinatorial Gata2 and Sca1 expression defines hematopoietic stem cells in the bone marrow niche (2006) (111)
- An embryonic/fetal β‐type globin gene repressor contains a nuclear receptor TR2/TR4 heterodimer (2002) (110)
- A Gata2 intronic enhancer confers its pan-endothelia-specific regulation (2007) (110)
- A potential mechanism for the impairment of nitric oxide formation caused by prolonged oral exposure to arsenate in rabbits. (2003) (108)
- Primitive erythropoiesis from mesodermal precursors expressing VE-cadherin, PECAM-1, Tie2, endoglin, and CD34 in the mouse embryo. (2006) (108)
- Notch-Nrf2 Axis: Regulation of Nrf2 Gene Expression and Cytoprotection by Notch Signaling (2013) (107)
- Nrf2 Regulates Neurogenesis and Protects Neural Progenitor Cells Against Aβ Toxicity (2014) (107)
- Pi class glutathione S-transferase genes are regulated by Nrf 2 through an evolutionarily conserved regulatory element in zebrafish. (2005) (106)
- Nrf2 Transcriptionally Activates the mafG Gene through an Antioxidant Response Element* (2005) (106)
- Global downstream pathway analysis reveals a dependence of oncogenic NF-E2-related factor 2 mutation on the mTOR growth signaling pathway. (2010) (106)
- iJGVD: an integrative Japanese genome variation database based on whole-genome sequencing (2015) (105)
- Abnormal Heart Development and Lung Remodeling in Mice Lacking the Hypoxia-Inducible Factor-Related Basic Helix-Loop-Helix PAS Protein NEPAS (2007) (105)
- Gata3 participates in a complex transcriptional feedback network to regulate sympathoadrenal differentiation (2006) (105)
- Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries (2021) (105)
- Genetic and pharmacologic evidence links oxidative stress to ventilator-induced lung injury in mice. (2007) (105)
- Japonica array: improved genotype imputation by designing a population-specific SNP array with 1070 Japanese individuals (2015) (104)
- Embryonic and fetal β‐globin gene repression by the orphan nuclear receptors, TR2 and TR4 (2007) (104)
- Human small Maf proteins form heterodimers with CNC family transcription factors and recognize the NF-E2 motif (1997) (104)
- Nuclear Factor E2-Related Factor 2-Dependent Myocardiac Cytoprotection Against Oxidative and Electrophilic Stress (2008) (103)
- Negative feedback regulation of lipopolysaccharide-induced inducible nitric oxide synthase gene expression by heme oxygenase-1 induction in macrophages. (2008) (103)
- Establishment and characterization of the thrombopoietin-dependent megakaryocytic cell line, UT-7/TPO. (1996) (103)
- Regulatory Nexus of Synthesis and Degradation Deciphers Cellular Nrf2 Expression Levels (2013) (102)
- Differential roles of GATA‐1 and GATA‐2 in growth and differentiation of mast cells (1998) (102)
- GATA1-related leukaemias (2008) (102)
- Impaired megakaryopoiesis and behavioral defects in mafG-null mutant mice. (1998) (100)
- Levels of vascular endothelial growth factor are elevated in patients with obstructive sleep apnea--hypopnea syndrome. (2001) (98)
- Proteasome Dysfunction Activates Autophagy and the Keap1-Nrf2 Pathway* (2014) (98)
- Halofuginone enhances the chemo‐sensitivity of cancer cells by suppressing NRF2 accumulation (2017) (97)
- Characterizing rare and low-frequency height-associated variants in the Japanese population (2019) (97)
- Ursodeoxycholic acid stimulates Nrf2-mediated hepatocellular transport, detoxification, and antioxidative stress systems in mice. (2008) (97)
- 3.5KJPNv2: an allele frequency panel of 3552 Japanese individuals including the X chromosome (2019) (97)
- Expression of costimulatory molecules B7‐1 (CD80) and B7‐2 (CD86) on human hepatocellular carcinoma (1997) (96)
- Essential Role of Synoviolin in Embryogenesis* (2005) (96)
- Deficiency in Nrf2-GSH signaling impairs type II cell growth and enhances sensitivity to oxidants. (2007) (95)
- Isolation and Characterization of Renal Erythropoietin-Producing Cells from Genetically Produced Anemia Mice (2011) (95)
- Activation of Maf/AP-1 Repressor Bach2 by Oxidative Stress Promotes Apoptosis and Its Interaction with Promyelocytic Leukemia Nuclear Bodies* (2002) (93)
- Disrupted erythropoietin signaling promotes obesity and alters hypothalamus proopiomelanocortin production (2011) (92)
- Ablation of Gata1 in adult mice results in aplastic crisis, revealing its essential role in steady-state and stress erythropoiesis. (2008) (91)
- The NHB1 (N-terminal homology box 1) sequence in transcription factor Nrf1 is required to anchor it to the endoplasmic reticulum and also to enable its asparagine-glycosylation. (2007) (90)
- NF-E2 domination over Nrf2 promotes ROS accumulation and megakaryocytic maturation. (2010) (89)
- Role of Nrf2 and p62/ZIP in the neurite outgrowth by carnosic acid in PC12h cells. (2010) (89)
- Antioxidants and Phase 2 Enzymes in Macrophages: Regulation by Nrf2 Signaling and Protection Against Oxidative and Electrophilic Stress (2008) (88)
- Isothiocyanates Reduce Mercury Accumulation via an Nrf2-Dependent Mechanism during Exposure of Mice to Methylmercury (2011) (88)
- Targeted deletion of nrf2 impairs lung development and oxidant injury in neonatal mice. (2012) (88)
- Identification and initial characterization of a fourth leader exon and promoter of the human IGF-II gene. (1990) (88)
- Amelioration of inflammation and tissue damage in sickle cell model mice by Nrf2 activation (2015) (88)
- The herbal medicine Inchin‐ko‐to inhibits liver cell apoptosis induced by transforming growth factor β1 (1996) (88)
- Effects of Aryl Hydrocarbon Receptor Signaling on the Modulation of Th1/Th2 Balance1 (2005) (88)
- The Tohoku Medical Megabank Project: Design and Mission. (2016) (87)
- Nrf2 Improves Leptin and Insulin Resistance Provoked by Hypothalamic Oxidative Stress. (2017) (87)
- The absence of macrophage Nrf2 promotes early atherogenesis. (2013) (86)
- Loss of Keap 1 Function Activates Nrf 2 and Provides Advantages for Lung Cancer Cell Growth (2008) (86)
- Overexpression of c-Maf contributes to T-cell lymphoma in both mice and human. (2006) (86)
- Interleukin-6 and Tumor Necrosis Factor-α in Patients with Obstructive Sleep Apnea-Hypopnea Syndrome (2004) (86)
- Dual Regulation of the Transcriptional Activity of Nrf1 by β-TrCP- and Hrd1-Dependent Degradation Mechanisms (2011) (86)
- Central nervous system‐specific deletion of transcription factor Nrf1 causes progressive motor neuronal dysfunction (2011) (85)
- Nrf2 Neh5 domain is differentially utilized in the transactivation of cytoprotective genes. (2007) (85)
- Nrf2-Mediated Regulation of Skeletal Muscle Glycogen Metabolism (2016) (85)
- EPR imaging of reducing activity in Nrf2 transcriptional factor-deficient mice. (2003) (84)
- Characterization of the pufferfish Otx2 cis-regulators reveals evolutionarily conserved genetic mechanisms for vertebrate head specification (2004) (83)
- Targeted Deletion of Nrf2 Reduces Urethane-Induced Lung Tumor Development in Mice (2011) (82)
- jMorp: Japanese Multi Omics Reference Panel (2017) (82)
- Nrf2 Enhances Cholangiocyte Expansion in Pten-Deficient Livers (2013) (81)
- Transcription factor Nrf2 maintains the basal expression of Mdm2: An implication of the regulation of p53 signaling by Nrf2. (2011) (81)
- Predictive base substitution rules that determine the binding and transcriptional specificity of Maf recognition elements (2006) (81)
- Leukemogenesis Caused by Incapacitated GATA-1 Function (2004) (81)
- Renal erythropoietin-producing cells in health and disease (2015) (80)
- A crucial role of Nrf2 in in vivo defense against oxidative damage by an environmental pollutant, pentachlorophenol. (2006) (80)
- Erythroleukemia differentiation. Distinctive responses of the erythroid-specific and the nonspecific delta-aminolevulinate synthase mRNA. (1991) (80)
- GATA factor switching during erythroid differentiation (2010) (79)
- Nrf2 regulates the alternative first exons of CD36 in macrophages through specific antioxidant response elements. (2008) (79)
- Keap1/Nrf2 pathway activation leads to a repressed hepatic gluconeogenic and lipogenic program in mice on a high-fat diet. (2016) (79)
- KEAP1 inhibition is neuroprotective and suppresses the development of epilepsy (2018) (79)
- Molecular Evolution of Keap1 (2008) (79)
- Forced GATA-1 expression in the murine myeloid cell line M1: induction of c-Mpl expression and megakaryocytic/erythroid differentiation. (1998) (79)
- Role of Nrf2 in Host Defense against Influenza Virus in Cigarette Smoke-Exposed Mice (2011) (79)
- Enhanced spontaneous and benzo(a)pyrene-induced mutations in the lung of Nrf2-deficient gpt delta mice. (2007) (78)
- Myeloid Lineage–Specific Deletion of Antioxidant System Enhances Tumor Metastasis (2014) (78)
- GATA Motifs Regulate Early Hematopoietic Lineage-Specific Expression of the Gata2 Gene (2005) (78)
- Deletion of the Selenocysteine tRNA Gene in Macrophages and Liver Results in Compensatory Gene Induction of Cytoprotective Enzymes by Nrf2*♦ (2008) (78)
- Nrf2 counteracts cholestatic liver injury via stimulation of hepatic defense systems. (2009) (77)
- Intestinal flora induces the expression of Cyp3a in the mouse liver (2009) (77)
- Environmental pollutants and the immune response (2020) (77)
- Structural Basis of Alternative DNA Recognition by Maf Transcription Factors (2009) (77)
- Hemogenic and nonhemogenic endothelium can be distinguished by the activity of fetal liver kinase (Flk)-1 promoter/enhancer during mouse embryogenesis. (2003) (77)
- Up-regulation of p27(kip1) contributes to Nrf2-mediated protection against angiotensin II-induced cardiac hypertrophy. (2011) (76)
- Hypoxia-inducible Transcription Factor-2α in Endothelial Cells Regulates Tumor Neovascularization through Activation of Ephrin A1* (2008) (76)
- Heme regulates B-cell differentiation, antibody class switch, and heme oxygenase-1 expression in B cells as a ligand of Bach2. (2011) (76)
- Nrf2 and p53 cooperatively protect against BBN-induced urinary bladder carcinogenesis. (2007) (76)
- Molecular Determinants of NOTCH4 Transcription in Vascular Endothelium (2005) (76)
- Nitro‐fatty acids and cyclopentenone prostaglandins share strategies to activate the Keap1‐Nrf2 system: a study using green fluorescent protein transgenic zebrafish (2011) (75)
- Roles Nrf2 Plays in Myeloid Cells and Related Disorders (2013) (75)
- NRF2 Is a Key Target for Prevention of Noise-Induced Hearing Loss by Reducing Oxidative Damage of Cochlea (2015) (75)
- NF-E2-Related Factor 1 (Nrf1) Serves as a Novel Regulator of Hepatic Lipid Metabolism through Regulation of the Lipin1 and PGC-1β Genes (2012) (75)
- Attenuation of UVB-induced sunburn reaction and oxidative DNA damage with no alterations in UVB-induced skin carcinogenesis in Nrf2 gene-deficient mice. (2008) (75)
- Induction of erythroid-specific gene expression in lymphoid cells. (1993) (74)
- NF‐E2‐related factor 2 regulates the stress response to UVA‐1‐oxidized phospholipids in skin cells (2010) (74)
- Oral administration of K-11706 inhibits GATA binding activity, enhances hypoxia-inducible factor 1 binding activity, and restores indicators in an in vivo mouse model of anemia of chronic disease. (2004) (74)
- Acceleration of UVB‐induced photoageing in nrf2 gene‐deficient mice (2011) (74)
- Transgene Insertion in Proximity to thec-myb Gene Disrupts Erythroid-Megakaryocytic Lineage Bifurcation (2006) (73)
- Activation of Nrf2 and accumulation of ubiquitinated A170 by arsenic in osteoblasts. (2003) (73)
- Runx1 is involved in primitive erythropoiesis in the mouse. (2008) (73)
- Antioxidant signaling via Nrf2 counteracts lipopolysaccharide-mediated inflammatory responses in foam cell macrophages. (2011) (73)
- NRF2 Intensifies Host Defense Systems to Prevent Lung Carcinogenesis, but After Tumor Initiation Accelerates Malignant Cell Growth. (2016) (73)
- Cohort Profile: Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study (TMM BirThree Cohort Study): rationale, progress and perspective (2019) (73)
- Genetic Evidence of an Evolutionarily Conserved Role for Nrf2 in the Protection against Oxidative Stress (2012) (73)
- GATA-2/estrogen receptor chimera regulates cytokine-dependent growth of hematopoietic cells through accumulation of p21(WAF1) and p27(Kip1) proteins. (2002) (72)
- Functional Analysis of Basic Transcription Element Binding Protein by Gene Targeting Technology (2003) (72)
- Nrf2 inhibits hepatic iron accumulation and counteracts oxidative stress-induced liver injury in nutritional steatohepatitis (2012) (71)
- Deletion of Nrf2 leads to rapid progression of steatohepatitis in mice fed atherogenic plus high-fat diet (2013) (71)
- Disruption of Nrf2 enhances susceptibility to airway inflammatory responses induced by low-dose diesel exhaust particles in mice. (2008) (71)
- Cloning and expression of human B cell-specific transcription factor BACH2 mapped to chromosome 6q15 (2000) (70)
- The Nrf3 Transcription Factor Is a Membrane-bound Glycoprotein Targeted to the Endoplasmic Reticulum through Its N-terminal Homology Box 1 Sequence* (2009) (70)
- A Constitutively Active Arylhydrocarbon Receptor Induces Growth Inhibition of Jurkat T Cells through Changes in the Expression of Genes Related to Apoptosis and Cell Cycle Arrest* (2004) (70)
- MAFG is a transcriptional repressor of bile acid synthesis and metabolism. (2015) (68)
- Solution structure of the DNA-binding domain of MafG (2002) (68)
- GATA factor switching from GATA2 to GATA1 contributes to erythroid differentiation (2013) (68)
- A simple method for amino acid selective isotope labeling of recombinant proteins in E. coli (2008) (68)
- Identification of somatic genetic alterations in ovarian clear cell carcinoma with next generation sequencing (2018) (67)
- Identification of human GATA-2 gene distal IS exon and its expression in hematopoietic stem cell fractions. (2000) (67)
- Fetal Globin Gene Repressors as Drug Targets for Molecular Therapies To Treat the β-Globinopathies (2014) (67)
- Direct Binding of pRb/E2F-2 to GATA-1 Regulates Maturation and Terminal Cell Division during Erythropoiesis (2009) (67)
- Mechanisms of transcription in eosinophils: GATA-1, but not GATA-2, transactivates the promoter of the eosinophil granule major basic protein gene. (1998) (67)
- Absolute Amounts and Status of the Nrf2-Keap1-Cul3 Complex within Cells (2016) (66)
- A GATA‐specific inhibitor (K‐7174) rescues anemia induced by IL‐1β, TNF‐α, or l‐NMMA (2003) (66)
- Acute erythropoietin cardioprotection is mediated by endothelial response (2011) (66)
- A functional role of Stat3 in in vivo megakaryopoiesis. (2002) (66)
- The KEAP1–NRF2 System as a Molecular Target of Cancer Treatment (2020) (66)
- Comparison of citrus coumarins on carcinogen-detoxifying enzymes in Nrf2 knockout mice. (2009) (66)
- Evidence for the transcriptional inhibition by heme of the synthesis of delta-aminolevulinate synthase in rat liver. (1982) (65)
- A mouse model of adult-onset anaemia due to erythropoietin deficiency (2013) (64)
- Innate Immunity against Bacterial Infection following Hyperoxia Exposure Is Impaired in NRF2-Deficient Mice1 (2009) (64)
- Gene expression regulation and domain function of hematopoietic GATA factors. (2005) (64)
- Constitutively Active Aryl Hydrocarbon Receptor Expressed Specifically in T-Lineage Cells Causes Thymus Involution and Suppresses the Immunization-Induced Increase in Splenocytes1 (2005) (64)
- Transcription Factor Nrf1 Negatively Regulates the Cystine/Glutamate Transporter and Lipid-Metabolizing Enzymes (2014) (64)
- Aggressive mammary carcinoma progression in Nrf2 knockout mice treated with 7,12-dimethylbenz[a]anthracene (2010) (64)
- Nrf2 Suppresses Oxidative Stress and Inflammation in App Knock-In Alzheimer’s Disease Model Mice (2020) (63)
- The triterpenoid CDDO-imidazolide confers potent protection against hyperoxic acute lung injury in mice. (2009) (63)
- Protective role of Nrf2 in age-related hearing loss and gentamicin ototoxicity. (2011) (62)
- Conditional expression of the ubiquitous transcription factor MafK induces erythroleukemia cell differentiation. (1995) (62)
- Rapid turnover of GATA‐2 via ubiquitin‐proteasome protein degradation pathway (2005) (62)
- Roles of Keap1–Nrf2 System in Upper Aerodigestive Tract Carcinogenesis (2012) (62)
- 12/15-Lipoxygenase-mediated enzymatic lipid oxidation regulates DC maturation and function. (2015) (62)
- Evaluation of MafG interaction with Maf recognition element arrays by surface plasmon resonance imaging technique (2004) (62)
- Tissue-Restricted Expression of Nrf2 and Its Target Genes in Zebrafish with Gene-Specific Variations in the Induction Profiles (2011) (61)
- A minigene containing four discrete cis elements recapitulates GATA‐1 gene expression in vivo (2002) (61)
- Systemic Activation of NRF2 Alleviates Lethal Autoimmune Inflammation in Scurfy Mice (2017) (61)
- Graded Levels of GATA-1 Expression Modulate Survival, Proliferation, and Differentiation of Erythroid Progenitors* (2005) (60)
- Increased susceptibility to hepatocarcinogenicity of Nrf2‐deficient mice exposed to 2‐amino‐3‐methylimidazo[4,5‐f]quinoline (2007) (60)
- Loss of a Rho-regulated actin nucleator, mDia2, impairs cytokinesis during mouse fetal erythropoiesis. (2013) (60)
- Multiple, Distant Gata2 Enhancers Specify Temporally and Tissue-Specific Patterning in the Developing Urogenital System (2004) (59)
- Nrf2 deficiency causes tooth decolourization due to iron transport disorder in enamel organ (2004) (59)
- Interethnic analyses of blood pressure loci in populations of East Asian and European descent (2018) (59)
- Expression of the aflatoxin B1-8,9-epoxide-metabolizing murine glutathione S-transferase A3 subunit is regulated by the Nrf2 transcription factor through an antioxidant response element. (2003) (59)
- A regulatory network governing Gata1 and Gata2 gene transcription orchestrates erythroid lineage differentiation (2014) (58)
- Notch signaling is necessary for GATA3 function in the initiation of T cell development (2008) (58)
- Nrf2 deficiency impairs the barrier function of mouse oesophageal epithelium (2013) (57)
- Deficiency in the transcription factor NRF2 worsens inflammatory parameters in a mouse model with combined tauopathy and amyloidopathy (2018) (57)
- Metabolic stress response implicated in diabetic retinopathy: The role of calpain, and the therapeutic impact of calpain inhibitor (2012) (57)
- Unique and Overlapping Transcriptional Roles of Arylhydrocarbon Receptor Nuclear Translocator (Arnt) and Arnt2 in Xenobiotic and Hypoxic Responses* (2006) (57)
- Keap1/Nrf2 system regulates neuronal survival as revealed through study of keap1 gene-knockout mice. (2009) (57)
- NRF2 immunolocalization in human breast cancer patients as a prognostic factor. (2014) (56)
- Characterization of GATA‐1+ hemangioblastic cells in the mouse embryo (2006) (56)
- Lansoprazole, a Proton Pump Inhibitor, Mediates Anti-Inflammatory Effect in Gastric Mucosal Cells through the Induction of Heme Oxygenase-1 via Activation of NF-E2-Related Factor 2 and Oxidation of Kelch-Like ECH-Associating Protein 1 (2009) (56)
- Nrf2 and selenoproteins are essential for maintaining oxidative homeostasis in erythrocytes and protecting against hemolytic anemia. (2011) (56)
- Nrf2 controls bone marrow stromal cell susceptibility to oxidative and electrophilic stress. (2006) (56)
- An Overview of the Advantages of KEAP1-NRF2 System Activation During Inflammatory Disease Treatment. (2017) (56)
- Embryonic Lethality and Fetal Liver Apoptosis in Mice Lacking All Three Small Maf Proteins (2011) (55)
- Redox cycling of 9,10-phenanthraquinone to cause oxidative stress is terminated through its monoglucuronide conjugation in human pulmonary epithelial A549 cells. (2008) (55)
- Persistent activation of Nrf 2 through p 62 in hepatocellular carcinoma cells (2011) (55)
- CNC-bZIP protein Nrf1-dependent regulation of glucose-stimulated insulin secretion. (2015) (55)
- Redox-Sensitive Transcription Factor Nrf2 Regulates Vascular Smooth Muscle Cell Migration and Neointimal Hyperplasia (2013) (55)
- Low-Dose Irradiation Promotes Persistent Oxidative Stress and Decreases Self-Renewal in Hematopoietic Stem Cells. (2017) (55)
- Inhibitory interaction of c-Myb and GATA-1 via transcriptional co-activator CBP (2000) (55)
- Transgenic expression of BACH1 transcription factor results in megakaryocytic impairment. (2005) (55)
- jMorp updates in 2020: large enhancement of multi-omics data resources on the general Japanese population (2020) (55)
- Conserved structure, regulatory elements, and transcriptional regulation from the GATA-1 gene testis promoter. (1997) (54)
- Sequential activation of genes for heme pathway enzymes during erythroid differentiation of mouse Friend virus-transformed erythroleukemia cells. (1991) (54)
- Molecular basis distinguishing the DNA binding profile of Nrf2-Maf heterodimer from that of Maf homodimer. (2015) (54)
- Upstream and downstream of erythroid transcription factor GATA‐1 (1997) (54)
- Differential Modulation of Keratin Expression by Sulforaphane Occurs via Nrf2-dependent and -independent Pathways in Skin Epithelia (2010) (54)
- The Mediator Subunit MED16 Transduces NRF2-Activating Signals into Antioxidant Gene Expression (2015) (54)
- Nrf2 inactivation enhances placental angiogenesis in a preeclampsia mouse model and improves maternal and fetal outcomes (2017) (54)
- Study Profile of the Tohoku Medical Megabank Community-Based Cohort Study (2020) (54)
- Loss of DNA binding ability of the transcription factor encoded by the mutant mi locus. (1994) (53)
- Molecular basis for the disruption of Keap1–Nrf2 interaction via Hinge & Latch mechanism (2021) (53)
- Nrf2 induces fibroblast growth factor 21 in diabetic mice (2014) (53)
- Nrf2 status affects tumor growth, HDAC3 gene promoter associations, and the response to sulforaphane in the colon (2015) (53)
- Role of Nrf2 in retinal vascular development and the vaso-obliterative phase of oxygen-induced retinopathy. (2007) (53)
- Pyridoxine refractory X-linked sideroblastic anemia caused by a point mutation in the erythroid 5-aminolevulinate synthase gene. (1997) (53)
- Expression of erythroid‐specific genes in acute megakaryoblastic leukaemia and transient myeloproliferative disorder in Down's syndrome (1995) (53)
- MafG Sumoylation Is Required for Active Transcriptional Repression (2006) (53)
- Abundant expression of transcription factor GATA-2 in proliferating but not in differentiated mast cells in tissues of mice: demonstration by in situ hybridization. (1996) (52)
- Hyperactivation of Nrf2 in early tubular development induces nephrogenic diabetes insipidus (2017) (52)
- Specific Contribution of the Erythropoietin Gene 3′ Enhancer to Hepatic Erythropoiesis after Late Embryonic Stages (2011) (52)
- Keap1 knockdown increases markers of metabolic syndrome after long-term high fat diet feeding. (2013) (51)
- The TR2 and TR4 orphan nuclear receptors repress Gata1 transcription. (2007) (51)
- Cytochrome P450 2A5 constitutive expression and induction by heavy metals is dependent on redox-sensitive transcription factor Nrf2 in liver. (2010) (51)
- Small Maf Compound Mutants Display Central Nervous System Neuronal Degeneration, Aberrant Transcription, and Bach Protein Mislocalization Coincident with Myoclonus and Abnormal Startle Response (2003) (51)
- Transgenic rescue of GATA-1-deficient mice with GATA-1 lacking a FOG-1 association site phenocopies patients with X-linked thrombocytopenia. (2004) (51)
- Nrf2 regulates NGF mRNA induction by carnosic acid in T98G glioblastoma cells and normal human astrocytes. (2011) (50)
- Increased susceptibility of Nrf2-null mice to 1-bromopropane-induced hepatotoxicity. (2010) (50)
- Temporal and spatial changes in GATA transcription factor expression are coincident with development of the chicken optic tectum. (1994) (50)
- Inducibility of cytochrome P450 1A1 and chemical carcinogenesis by benzo[a]pyrene in AhR repressor-deficient mice. (2008) (50)
- Activation of the NRF2 pathway and its impact on the prognosis of anaplastic glioma patients. (2015) (50)
- Translational inhibition by heme of the synthesis of hepatic delta-aminolevulinate synthase in a cell-free system. (1983) (50)
- The nuclear factor erythroid 2-related factor 2 activator oltipraz attenuates chronic hypoxia-induced cardiopulmonary alterations in mice. (2013) (50)
- Nrf2 in bone marrow-derived cells positively contributes to the advanced stage of atherosclerotic plaque formation. (2012) (50)
- MafT, a new member of the small Maf protein family in zebrafish. (2004) (50)
- Select heterozygous Keap1 mutations have a dominant-negative effect on wild-type Keap1 in vivo. (2011) (49)
- Unique cistrome defined as CsMBE is strictly required for Nrf2-sMaf heterodimer function in cytoprotection. (2016) (49)
- Transforming Growth Factor-β Induces Transcription Factors MafK and Bach1 to Suppress Expression of the Heme Oxygenase-1 Gene* (2013) (49)
- Differential Contribution of the Gata1 Gene Hematopoietic Enhancer to Erythroid Differentiation (2008) (49)
- Aberrant iron accumulation and oxidized status of erythroid-specific delta-aminolevulinate synthase (ALAS2)-deficient definitive erythroblasts. (2003) (49)
- Initial response and cellular protection through the Keap1/Nrf2 system during the exposure of primary mouse hepatocytes to 1,2-naphthoquinone. (2011) (48)
- Compound mouse mutants of bZIP transcription factors Mafg and Mafk reveal a regulatory network of non-crystallin genes associated with cataract (2015) (48)
- C151 in KEAP1 is the main cysteine sensor for the cyanoenone class of NRF2 activators, irrespective of molecular size or shape (2018) (48)
- Hypoxia Signaling Cascade for Erythropoietin Production in Hepatocytes (2015) (47)
- Nrf2 enhances myocardial clearance of toxic ubiquitinated proteins. (2014) (47)
- Genome-wide identification of inter-individually variable DNA methylation sites improves the efficacy of epigenetic association studies (2017) (47)
- Genome-wide meta-analysis in Japanese populations identifies novel variants at the TMC6–TMC8 and SIX3–SIX2 loci associated with HbA1c (2017) (47)
- Identification of Nrf 2-regulated Genes Induced by the Chemopreventive Agent Sulforaphane by Oligonucleotide Microarray 1 (2002) (47)
- Gene expression of detoxifying enzymes in AhR and Nrf2 compound null mutant mouse. (2003) (47)
- Establishment of Protocols for Global Metabolomics by LC-MS for Biomarker Discovery (2016) (47)
- Differential effects of GATA-1 on proliferation and differentiation of erythroid lineage cells. (2006) (46)
- Nrf2 deficiency in myeloid cells is not sufficient to protect mice from high-fat diet-induced adipose tissue inflammation and insulin resistance. (2012) (46)
- Generation of a New Model Rat: Nrf2 Knockout Rats Are Sensitive to Aflatoxin B1 Toxicity. (2016) (46)
- GATA-1 blocks IL-6-induced macrophage differentiation and apoptosis through the sustained expression of cyclin D1 and bcl-2 in a murine myeloid cell line M1. (2000) (45)
- Nrf2/Keap1 system regulates vascular smooth muscle cell apoptosis for vascular homeostasis: role in neointimal formation after vascular injury (2016) (45)
- Inter-Individual Differences in the Oral Bacteriome Are Greater than Intra-Day Fluctuations in Individuals (2015) (45)
- Roles of renal erythropoietin-producing (REP) cells in the maintenance of systemic oxygen homeostasis (2015) (45)
- Suppressive effect of the herbal medicine Oren-gedoku-to on cyclooxygenase-2 activity and azoxymethane-induced aberrant crypt foci development in rats. (2000) (45)
- A human temperature-sensitive p53 mutant p53Val-138: modulation of the cell cycle, viability and expression of p53-responsive genes. (1995) (45)
- Inducible disruption of autophagy in the lung causes airway hyper-responsiveness. (2011) (45)
- Isolation of recombinant cDNAs encoding chicken erythroid delta-aminolevulinate synthase. (1985) (45)
- Self-Association of Gata1 Enhances Transcriptional Activity In Vivo in Zebra Fish Embryos (2003) (44)
- Increased dosage of Runx1/AML1 acts as a positive modulator of myeloid leukemogenesis in BXH2 mice (2005) (44)
- Degradation of Keap1 activates BH3-only proteins Bim and PUMA during hepatocyte lipoapoptosis (2014) (44)
- Roles of the KEAP1‐NRF2 system in mammalian skin exposed to UV radiation (2018) (44)
- Deficient heme and globin synthesis in embryonic stem cells lacking the erythroid-specific delta-aminolevulinate synthase gene. (1998) (43)
- Inhibition of thymocyte apoptosis by berberine. (1997) (43)
- α‐Fetoprotein impairs activation of natural killer cells by inhibiting the function of dendritic cells (2011) (43)
- Effects of long-term psychological stress on sexual behavior and brain catecholamine levels. (1996) (42)
- Nrf2 promotes mutant K-ras/p53-driven pancreatic carcinogenesis (2017) (42)
- Keap1‐Nrf2 system regulates cell fate determination of hematopoietic stem cells (2014) (42)
- Functional links between SQSTM1 and ALS2 in the pathogenesis of ALS: cumulative impact on the protection against mutant SOD1-mediated motor dysfunction in mice. (2016) (42)
- Dual-color luciferase mouse directly demonstrates coupled expression of two clock genes. (2010) (41)
- Regulation of hypoxia‐inducible gene expression after HIF activation (2017) (41)
- The subcellular localization and activity of cortactin is regulated by acetylation and interaction with Keap1 (2015) (41)
- Association of Keap1 and Nrf2 Genetic Mutations and Polymorphisms With Endometrioid Endometrial Adenocarcinoma Survival (2011) (41)
- The role of the Nrf2-mediated defense system in corneal epithelial wound healing. (2013) (40)
- Regulation of synthesis and intracellular translocation of delta-aminolevulinate synthase by heme and its relation to the heme saturation of tryptophan pyrrolase in rat liver. (1981) (40)
- Interleukin-6 and tumor necrosis factor-alpha in patients with obstructive sleep apnea-hypopnea syndrome. (2004) (40)
- A Homeostatic Shift Facilitates Endoplasmic Reticulum Proteostasis through Transcriptional Integration of Proteostatic Stress Response Pathways (2016) (40)
- Endogenous erythropoietin signaling facilitates skeletal muscle repair and recovery following pharmacologically induced damage (2012) (40)
- Disruption of the Hbs1l-Myb Locus Causes Hereditary Persistence of Fetal Hemoglobin in a Mouse Model (2013) (40)
- Transcription factor NF‐E2‐related factor 1 impairs glucose metabolism in mice (2014) (40)
- The Transcription Factor Nrf 2 Is a Therapeutic Target against Brain Inflammation 1 (2008) (39)
- Modulation of lung local immune responses by oral administration of a herbal medicine Sho-saiko-to. (2000) (39)
- Overview of redox regulation by Keap1–Nrf2 system in toxicology and cancer (2016) (39)
- Carcinogenesis and transcriptional regulation through Maf recognition elements (2007) (39)
- Isocitrate dehydrogenase mutation is frequently observed in giant cell tumor of bone (2014) (39)
- Biallelic GALM pathogenic variants cause a novel type of galactosemia (2018) (39)
- Cis-element architecture of Nrf2–sMaf heterodimer binding sites and its relation to diseases (2019) (39)
- GATA2 regulates dendritic cell differentiation. (2015) (38)
- Erythropoietin production in neuroepithelial and neural crest cells during primitive erythropoiesis (2013) (38)
- Nrf2 deficiency leads to behavioral, neurochemical and transcriptional changes in mice (2013) (38)
- Analysis of the role of Nrf2 in the expression of liver proteins in mice using two-dimensional gel-based proteomics. (2012) (38)
- 2‐oxoglutarate downregulates expression of vascular endothelial growth factor and erythropoietin through decreasing hypoxia‐inducible factor‐1α and inhibits angiogenesis (2006) (38)
- Genetic Predisposition to Ischemic Stroke (2017) (38)
- Genome analyses for the Tohoku Medical Megabank Project towards establishment of personalized healthcare (2018) (37)
- Ablation of the Transcription Factor Nrf2 Promotes Ischemia-Induced Neovascularization by Enhancing the Inflammatory Response (2010) (37)
- Reduced BMP4 abundance in Gata2 hypomorphic mutant mice result in uropathies resembling human CAKUT (2008) (37)
- O-GlcNAcylation Signal Mediates Proteasome Inhibitor Resistance in Cancer Cells by Stabilizing NRF1 (2018) (37)
- Transgenic overexpression of GATA-3 in T lymphocytes improves autoimmune glomerulonephritis in mice with a BXSB/MpJ-Yaa genetic background. (2003) (37)
- The Human Prepro-orexin Gene Regulatory Region That Activates Gene Expression in the Lateral Region and Represses It in the Medial Regions of the Hypothalamus* (2002) (36)
- NRF2 Activation Impairs Quiescence and Bone Marrow Reconstitution Capacity of Hematopoietic Stem Cells (2017) (36)
- Use of gene-manipulated mice in the study of erythropoietin gene expression. (2007) (36)
- Suppression of erythropoietin gene expression by cadmium depends on inhibition of HIF-1, not stimulation of GATA-2 (2003) (36)
- Genetic Predisposition to Ischemic Stroke A Polygenic Risk Score (2017) (36)
- Hepatocyte-specific deletion of heme oxygenase-1 disrupts redox homeostasis in basal and oxidative environments. (2008) (36)
- Differential roles for Nrf2 and AP-1 in upregulation of HO-1 expression by arsenite in murine embryonic fibroblasts (2008) (36)
- A GATA-specific inhibitor (K-7174) rescues anemia induced by IL-1beta, TNF-alpha, or L-NMMA. (2003) (36)
- GATA Transcription Factors Inhibit Cytokine-dependent Growth and Survival of a Hematopoietic Cell Line through the Inhibition of STAT3 Activity* (2005) (35)
- GATA2 Regulates Body Water Homeostasis through Maintaining Aquaporin 2 Expression in Renal Collecting Ducts (2014) (35)
- GATA-1 is required for expression of Fc{epsilon}RI on mast cells: analysis of mast cells derived from GATA-1 knockdown mouse bone marrow. (2005) (35)
- Nrf2 activation attenuates genetic endoplasmic reticulum stress induced by a mutation in the phosphomannomutase 2 gene in zebrafish (2018) (35)
- Highly Potent Activation of Nrf2 by Topical Tricyclic Bis(Cyano Enone): Implications for Protection against UV Radiation during Thiopurine Therapy (2012) (35)
- 1-Cyano-2,3-epithiopropane is a novel plant-derived chemopreventive agent which induces cytoprotective genes that afford resistance against the genotoxic alpha,beta-unsaturated aldehyde acrolein. (2009) (35)
- NRF2 mitigates acute alcohol-induced hepatic and pancreatic injury in mice. (2018) (35)
- An efficient quantitation method of next-generation sequencing libraries by using MiSeq sequencer. (2014) (35)
- Nrf2 is closely related to allergic airway inflammatory responses induced by low-dose diesel exhaust particles in mice. (2010) (34)
- LSD1/KDM1A promotes hematopoietic commitment of hemangioblasts through downregulation of Etv2 (2015) (34)
- Selective Induction of the Tumor Marker Glutathione S-Transferase P1 by Proteasome Inhibitors*[boxs] (2005) (34)
- Phenethyl Isothiocyanate, a Dual Activator of Transcription Factors NRF2 and HSF1 (2018) (34)
- Exacerbated Airway Toxicity of Environmental Oxidant Ozone in Mice Deficient in Nrf2 (2013) (34)
- Biologic significance of GATA-1 activities in Ras-mediated megakaryocytic differentiation of hematopoietic cell lines (2000) (34)
- Partial contribution of the Keap1-Nrf2 system to cadmium-mediated metallothionein expression in vascular endothelial cells. (2016) (33)
- Omics research project on prospective cohort studies from the Tohoku Medical Megabank Project (2018) (33)
- Security controls in an integrated Biobank to protect privacy in data sharing: rationale and study design (2017) (33)
- Effect of growth factors on ex vivo bone marrow cell expansion using three-dimensional matrix support. (2002) (33)
- Rottlerin synergistically enhances imatinib-induced apoptosis of BCR/ABL-expressing cells through its mitochondrial uncoupling effect independent of protein kinase C-δ (2007) (33)
- The Flavanol (−)-Epicatechin Prevents Stroke Damage through the Nrf2/HO1 Pathway (2014) (33)
- Keap1 inhibition attenuates glomerulosclerosis. (2014) (33)
- Nuclear Factor Erythroid 2–Related Factor 2 Regulates Toll-Like Receptor 4 Innate Responses in Mouse Liver Ischemia-Reperfusion Injury Through Akt-Forkhead box Protein O1 Signaling Network (2014) (33)
- GATA2 is critical for the maintenance of cellular identity in differentiated mast cells derived from mouse bone marrow. (2015) (33)
- Synthesis of Keap1-phosphorylated p62 and Keap1-Nrf2 protein-protein interaction inhibitors and their inhibitory activity. (2016) (33)
- Human erythropoietic protoporphyria: identification of a mutation at the splice donor site of intron 7 causing exon 7 skipping of the ferrochelatase gene. (1993) (33)
- Erythropoietin contributes to slow oxidative muscle fiber specification via PGC-1α and AMPK activation. (2013) (33)
- GATA2 regulates differentiation of bone marrow-derived mesenchymal stem cells (2014) (33)
- Molecular mechanism of transcriptional repression of AhR repressor involving ANKRA2, HDAC4, and HDAC5. (2007) (33)
- Infiltration of M1, but not M2, macrophages is impaired after unilateral ureter obstruction in Nrf2-deficient mice (2017) (33)
- Transcript Profiling Identifies Dynamic Gene Expression Patterns and an Important Role for Nrf2/Keap1 Pathway in the Developing Mouse Esophagus (2012) (32)
- Luminal alkalinization attenuates proteinuria-induced oxidative damage in proximal tubular cells. (2011) (32)
- Genetic Analysis of Hierarchical Regulation for Gata1 and NF-E2 p45 Gene Expression in Megakaryopoiesis (2010) (32)
- The role of the erythroid-specific delta-aminolevulinate synthase gene expression in erythroid heme synthesis. (1995) (32)
- Induction of hyperproliferative fetal megakaryopoiesis by an N‐terminally truncated GATA1 mutant (2009) (32)
- Transgenic rescue of erythroid 5‐aminolevulinate synthase‐deficient mice results in the formation of ring sideroblasts and siderocytes (2006) (32)
- NF-E2 p45 Is Important for Establishing Normal Function of Platelets (2013) (32)
- Dynamic regulation of Gata factor levels is more important than their identity (2007) (31)
- Biobank Establishment and Sample Management in the Tohoku Medical Megabank Project. (2019) (31)
- Runx1 is involved in the fusion of the primary and the secondary palatal shelves. (2009) (31)
- Nrf2-mediated Induction of Cytoprotective Enzymes by 15-Deoxy-Δ12,14-Prostaglandin J2 Is Attenuated by Alkenal/one Oxidoreductase* (2006) (31)
- XXIV World Allergy Congress 2015 (2016) (31)
- The Gata1 5' region harbors distinct cis-regulatory modules that direct gene activation in erythroid cells and gene inactivation in HSCs. (2013) (31)
- Genetic inactivation of Nrf2 prevents clonal expansion of initiated cells in a nutritional model of rat hepatocarcinogenesis. (2018) (31)
- Evaluation of reported pathogenic variants and their frequencies in a Japanese population based on a whole-genome reference panel of 2049 individuals (2018) (30)
- Histidine Decarboxylase Expression in Mouse Mast Cell Line P815 Is Induced by Mouse Peritoneal Cavity Incubation* (1996) (30)
- N(G)-monomethyl-L-arginine inhibits erythropoietin gene expression by stimulating GATA-2. (2000) (30)
- Impairment of erythroid and megakaryocytic differentiation by a Leukemia‐Associated and t(9;9)‐derived fusion gene product, SET/TAF‐Iβ‐CAN/Nup214 (2008) (30)
- The Transcription Factor Bach2 Is Phosphorylated at Multiple Sites in Murine B Cells but a Single Site Prevents Its Nuclear Localization* (2015) (30)
- Adipocyte-specific deficiency of Nfe2l1 disrupts plasticity of white adipose tissues and metabolic homeostasis in mice. (2018) (30)
- Activation of nuclear factor E2‐related factor 2 in hereditary tyrosinemia type 1 and its role in survival and tumor development (2008) (29)
- Transcriptional regulation by GATA1 and GATA2 during erythropoiesis (2011) (29)
- Purification and structure of rat erythroid-specific delta-aminolevulinate synthase. (1993) (29)
- Nuclear Factor Erythroid 2-Related Factor 2 Drives Podocyte-Specific Expression of Peroxisome Proliferator-Activated Receptor γ Essential for Resistance to Crescentic GN. (2016) (29)
- GATA-1 Self-association Controls Erythroid Development in Vivo* (2007) (29)
- Critical role of Myc activation in mouse hepatocarcinogenesis induced by the activation of AKT and RAS pathways (2017) (29)
- GATA‐1 testis activation region is essential for Sertoli cell‐specific expression of GATA‐1 gene in transgenic mouse (2003) (29)
- N- and C-terminal Transactivation Domains of GATA1 Protein Coordinate Hematopoietic Program* (2012) (29)
- Regulation of YB-1 gene expression by GATA transcription factors. (2003) (29)
- Enhancer remodeling promotes tumor-initiating activity in NRF2-activated non-small cell lung cancers (2020) (29)
- NG-monomethyl-l-arginine inhibits erythropoietin gene expression by stimulating GATA-2 (2000) (28)
- Functional Characterization of 21 Allelic Variants of Dihydropyrimidine Dehydrogenase Identified in 1070 Japanese Individuals (2018) (28)
- Regulation of GATA1 gene expression. (2007) (28)
- Possible involvement of oxidative stress in 5-fluorouracil-mediated myelosuppression in mice. (2011) (28)
- GATA-related hematologic disorders. (2016) (28)
- Novel serpinopathy in rat kidney and pancreas induced by overexpression of megsin. (2005) (28)
- Two chronic myelogenous leultaemia cell lines which represent different stages of erythroid differentiation (1993) (28)
- Loss of Nrf2 in mice evokes a congenital intrahepatic shunt that alters hepatic oxygen and protein expression gradients and toxicity. (2014) (28)
- The novel Nrf2 inducer TFM‐735 ameliorates experimental autoimmune encephalomyelitis in mice (2017) (28)
- Neither MafA/L‐Maf nor MafB is essential for lens development in mice (2009) (28)
- Microenvironmental Activation of Nrf2 Restricts the Progression of Nrf2-Activated Malignant Tumors (2020) (28)
- Expression of c-erbB-2 in human esophageal carcinoma cells: overexpression correlated with gene amplification or with GATA-3 transcription factor expression. (1993) (27)
- Molecular Basis Distinguishing the DNA Binding Profile of Nrf2-Maf Heterodimer from That of Maf Homodimer* (2007) (27)
- Induction of murine intestinal and hepatic peroxiredoxin MSP23 by dietary butylated hydroxyanisole. (2000) (27)
- Biologic significance of GATA-1 activities in Ras-mediated megakaryocytic differentiation of hematopoietic cell lines. (2000) (27)
- GATA Suppresses Erythropoietin Gene Expression through GATA Site in Mouse Erythropoietin Gene Promoter (2002) (27)
- A Possible Role of Nrf2 in Prevention of Renal Oxidative Damage by Ferric Nitrilotriacetate (2008) (27)
- A novel mutation of the erythroid‐specific δ‐aminolaevulinate synthase gene in a patient with X‐linked sideroblastic anaemia (1999) (27)
- NF‐E2‐related factor 2 promotes compensatory liver hypertrophy after portal vein branch ligation in mice (2014) (27)
- Identification of Celastramycin as a Novel Therapeutic Agent for Pulmonary Arterial Hypertension-High-throughput Screening of 5,562 Compounds. (2019) (27)
- Regulation of adipocyte differentiation of bone marrow stromal cells by transcription factor GATA-2. (2007) (27)
- Palmitate deranges erythropoietin production via transcription factor ATF4 activation of unfolded protein response. (2018) (27)
- Regulation of GATA Factor Expression Is Distinct between Erythroid and Mast Cell Lineages (2012) (26)
- An immunochemical study of δ-aminolevulinate synthase and δ-aminolevulinate dehydratase in liver and erythroid cells of rat☆ (1986) (26)
- Nrf2 deficiency improves autoimmune nephritis caused by the fas mutation lpr. (2004) (26)
- Transcription Factor GATA1 Is Dispensable for Mast Cell Differentiation in Adult Mice (2014) (26)
- PGC-1 Coactivator Activity Is Required for Murine Erythropoiesis (2014) (26)
- NFE2-Related Transcription Factor 2 Coordinates Antioxidant Defense with Thyroglobulin Production and Iodination in the Thyroid Gland. (2018) (26)
- In vivo gene transfer and expression in rat stomach by submucosal injection of plasmid DNA. (1996) (26)
- Macrophages Switch Their Phenotype by Regulating Maf Expression during Different Phases of Inflammation (2018) (26)
- GATA2 haploinsufficiency accelerates EVI1-driven leukemogenesis. (2017) (26)
- Transethnic meta-analysis of genome-wide association studies identifies three new loci and characterizes population-specific differences for coronary artery disease (2019) (26)
- Tissue Prx I in the protection against Fe-NTA and the reduction of nitroxyl radicals. (2006) (25)
- Adjustment of Cell-Type Composition Minimizes Systematic Bias in Blood DNA Methylation Profiles Derived by DNA Collection Protocols (2016) (25)
- Bardoxolone methyl analog attenuates proteinuria-induced tubular damage by modulating mitochondrial function (2019) (25)
- Sulforaphane enriched transcriptome of lung mitochondrial energy metabolism and provided pulmonary injury protection via Nrf2 in mice (2019) (25)
- Erythropoietin-dependent induction of hemoglobin synthesis in a cytokine-dependent cell line M-TAT. (1994) (25)
- Whole-Body In Vivo Monitoring of Inflammatory Diseases Exploiting Human Interleukin 6-Luciferase Transgenic Mice (2015) (25)
- Cell-cycle-dependent oscillation of GATA2 expression in hematopoietic cells. (2006) (25)
- Construction and integration of three de novo Japanese human genome assemblies toward a population-specific reference (2019) (24)
- Hyperactivation of Nrf2 leads to hypoplasia of bone in vivo (2018) (24)
- Isolation and characterization of zebrafish NFE2. (2002) (24)
- Nrf2 deficiency promotes the progression from acute tubular damage to chronic renal fibrosis following unilateral ureteral obstruction (2017) (24)
- Dynamic regulation of Gata factor levels is more important than their identity. (2007) (24)
- Nrf2 contributes to the weight gain of mice during space travel (2020) (24)
- Transcription Factor Nrf 2 Plays a Pivotal Role in Protection against Elastase-Induced Pulmonary Inflammation and Emphysema 1 (2005) (24)
- Structural insights into the similar modes of Nrf2 transcription factor recognition by the cytoplasmic repressor Keap1 (2008) (23)
- Nrf2 Suppresses Allergic Lung Inflammation by Attenuating the Type 2 Innate Lymphoid Cell Response (2019) (23)
- Genetic analysis of Japanese primary open-angle glaucoma patients and clinical characterization of risk alleles near CDKN2B-AS1, SIX6 and GAS7 (2017) (23)
- Indispensable function for embryogenesis, expression and regulation of the nonspecific form of the 5‐aminolevulinate synthase gene in mouse (2010) (23)
- Eczema and Asthma Symptoms among Schoolchildren in Coastal and Inland Areas after the 2011 Great East Japan Earthquake: The ToMMo Child Health Study. (2015) (23)
- Nrf2 represses the onset of type 1 diabetes in non-obese diabetic mice. (2019) (23)
- Real-time monitoring of stress erythropoiesis in vivo using Gata1 and beta-globin LCR luciferase transgenic mice. (2006) (23)
- Naturally occurring oncogenic GATA1 mutants with internal deletions in transient abnormal myelopoiesis in Down syndrome. (2013) (22)
- Erythropoietin gene expression by hydrogen peroxide. (1996) (22)
- Impacts of NRF2 activation in non–small‐cell lung cancer cell lines on extracellular metabolites (2019) (22)
- Environmental Electrophile-Mediated Toxicity in Mice Lacking Nrf2, CSE, or Both (2019) (22)
- Discovery of benzo[g]indoles as a novel class of non-covalent Keap1-Nrf2 protein-protein interaction inhibitor. (2017) (22)
- Risk of chronic kidney disease in non-obese individuals with clustering of metabolic factors: a longitudinal study. (2015) (22)
- The structural origin of metabolic quantitative diversity (2016) (22)
- Iron attenuates erythropoietin production by decreasing hypoxia-inducible transcription factor 2α concentrations in renal interstitial fibroblasts. (2018) (22)
- Expression of GATA transcription factors in myelogenous and lymphoblastic leukemia cells. (1997) (22)
- A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism (2020) (22)
- Suppression of AhR signaling pathway is associated with the down-regulation of UDP-glucuronosyltransferases during BBN-induced urinary bladder carcinogenesis in mice. (2010) (22)
- Identification of a novel transcription unit in the human insulin-like growth factor-II gene. (1991) (22)
- Alcohol dehydrogenase 3 contributes to the protection of liver from nonalcoholic steatohepatitis (2015) (21)
- Nrf2 transactivator-independent GSTP1-1 expression in "GSTP1-1 positive" single cells inducible in female mouse liver by DEN: a preneoplastic character of possible initiated cells. (2002) (21)
- An integrative approach to analyze microarray datasets for prioritization of genes relevant to lens biology and disease (2015) (21)
- Reducing Inflammatory Cytokine Production from Renal Collecting Duct Cells by Inhibiting GATA2 Ameliorates Acute Kidney Injury (2017) (21)
- Quantitative analysis of UV photolesions suggests that cyclobutane pyrimidine dimers produced in mouse skin by UVB are more mutagenic than those produced by UVC. (2018) (21)
- GATA4 immunolocalization in breast carcinoma as a potent prognostic predictor (2014) (20)
- Pathogenic mutations identified by a multimodality approach in 117 Japanese Fanconi anemia patients (2019) (20)
- Nrf2 degron‐fused reporter system: a new tool for specific evaluation of Nrf2 inducers (2011) (20)
- Tumors sweeten macrophages with acids (2018) (20)
- Inhibitors of the protein–protein interaction between phosphorylated p62 and Keap1 attenuate chemoresistance in a human hepatocellular carcinoma cell line (2020) (20)
- Keap1 regulates the constitutive expression of GST A1 during differentiation of Caco-2 cells. (2008) (20)
- 5-Aminolevulinate synthase expression and hemoglobin synthesis in a human myelogenous leukemia cell line. (1997) (20)
- Transcription factor regulation of hematopoietic lineage cells. (1991) (20)
- Identification of a Functional Antioxidant Response Element within the Eighth Intron of the Human ABCC3 Gene (2015) (20)
- Differential regulation of coproporphyrinogen oxidase gene between erythroid and nonerythroid cells. (1998) (20)
- Functional characterization of the two alternative promoters of human p45 NF-E2 gene. (2000) (20)
- Possible involvement of nuclear factor erythroid 2-related factor 2 in the gene expression of Cyp2b10 and Cyp2a5 (2014) (20)
- Structure and expression of the gene encoding rat nonspecific form delta-aminolevulinate synthase. (1993) (19)
- An immortalized cell line derived from renal erythropoietin-producing (REP) cells demonstrates their potential to transform into myofibroblasts (2019) (19)
- Differential Regulation of Coproporphyrinogen Oxidase Gene Between Erythroid and Nonerythroid Cells (1998) (19)
- Abundant expression of erythroid transcription factor P45 NF-E2 mRNA in human peripheral granurocytes. (1996) (19)
- R411C mutation of the ALAS2 gene encodes a pyridoxine‐responsive enzyme with low activity (1998) (19)
- Small Maf deficiency recapitulates the liver phenotypes of Nrf1‐ and Nrf2‐deficient mice (2016) (19)
- Sulforaphane ameliorates steroid insensitivity through an Nrf2‐dependent pathway in cigarette smoke‐exposed asthmatic mice (2018) (19)
- Transcription Factor MAFF (MAF Basic Leucine Zipper Transcription Factor F) Regulates an Atherosclerosis Relevant Network Connecting Inflammation and Cholesterol Metabolism (2021) (19)
- Identification of genetic alterations in extramammary Paget disease using whole exome analysis. (2019) (19)
- GATA-4 Incompletely Substitutes for GATA-1 in Promoting Both Primitive and Definitive Erythropoiesis in Vivo* (2006) (19)
- Role of Nrf2 in inflammatory response in lung of mice exposed to zinc oxide nanoparticles (2019) (19)
- Establishment of Integrated Biobank for Precision Medicine and Personalized Healthcare: The Tohoku Medical Megabank Project (2019) (19)
- The Distal Sequence Element of the Selenocysteine tRNA Gene Is a Tissue-Dependent Enhancer Essential for Mouse Embryogenesis (2005) (19)
- Carbocisteine reduces virus-induced pulmonary inflammation in mice exposed to cigarette smoke. (2014) (19)
- Leukemia‐related transcription factor TEL/ETV6 expands erythroid precursors and stimulates hemoglobin synthesis (2009) (18)
- Mature erythrocyte membrane homeostasis is compromised by loss of the GATA1-FOG1 interaction. (2012) (18)
- O-Glycan-Altered Extracellular Vesicles: A Specific Serum Marker Elevated in Pancreatic Cancer (2020) (18)
- The promoter of mouse transcription repressor bach1 is regulated by Sp1 and trans-activated by Bach1. (2001) (18)
- Suppression of SLC11A2 expression is essential to maintain duodenal integrity during dietary iron overload. (2010) (18)
- A novel type of E 3-ligase for the Ufm 1-conjugation system (2009) (18)
- Cloning of a coproporphyrinogen oxidase promoter regulatory element binding protein. (2000) (18)
- Characterization of a Functional ZBP-89 Binding Site That Mediates Gata1 Gene Expression during Hematopoietic Development* (2009) (18)
- Renal Anemia Model Mouse Established by Transgenic Rescue with an Erythropoietin Gene Lacking Kidney-Specific Regulatory Elements (2016) (18)
- Nrf2 deficiency aggravates the increase in osteoclastogenesis and bone loss induced by inorganic arsenic (2019) (18)
- Concurrent transcriptional deregulation of AML1/RUNX1 and GATA factors by the AML1-TRPS1 chimeric gene in t(8;21)(q24;q22) acute myeloid leukemia. (2007) (17)
- Contribution of GATA1 dysfunction to multi‐step leukemogenesis (2012) (17)
- Elimination of Pasteurella pneumotropica from a contaminated mouse colony by oral administration of Enrofloxacin. (2002) (17)
- In vivo promoter analysis on refeeding response of hepatic sterol regulatory element-binding protein-1c expression. (2007) (17)
- L-arginine rescues decreased erythropoietin gene expression by stimulating GATA-2 with L-NMMA. (2002) (17)
- UG4 Enhancer-Driven GATA-2 and Bone Morphogenetic Protein 4 Complementation Remedies the CAKUT Phenotype in Gata2 Hypomorphic Mutant Mice (2012) (17)
- Remarkable induction of UV-signature mutations at the 3'-cytosine of dipyrimidine sites except at 5'-TCG-3' in the UVB-exposed skin epidermis of xeroderma pigmentosum variant model mice. (2014) (17)
- Direct and Specific Functional Evaluation of the Nrf2 and MafG Heterodimer by Introducing a Tethered Dimer into Small Maf-Deficient Cells (2019) (17)
- Loss of the Gata1 Gene IE Exon Leads to Variant Transcript Expression and the Production of a GATA1 Protein Lacking the N-terminal Domain* (2009) (17)
- Defining the Functional Boundaries of the Gata2 Locus by Rescue with a Linked Bacterial Artificial Chromosome Transgene* (2008) (17)
- Molecular Determinants for Small Maf Protein Control of Platelet Production (2010) (16)
- Geldanamycin-Derived HSP90 Inhibitors Are Synthetic Lethal with NRF2 (2020) (16)
- Simultaneous K-ras activation and Keap1 deletion cause atrophy of pancreatic parenchyma. (2018) (16)
- Expression of constitutively-active aryl hydrocarbon receptor in T-cells enhances the down-regulation of CD62L, but does not alter expression of CD25 or suppress the allogeneic CTL response (2009) (16)
- Cell-cycle-dependent regulation of erythropoietin receptor gene. (1997) (16)
- Influence of chronic kidney disease on hospitalization, chronic dialysis, and mortality in Japanese men: a longitudinal analysis (2017) (16)
- Purification, crystallization and preliminary X-ray diffraction analysis of the Kelch-like motif region of mouse Keap1. (2005) (16)
- Constitutive activation of nuclear factor‐E2‐related factor 2 induces biotransformation enzyme and transporter expression in livers of mice with hepatocyte‐specific deletion of Kelch‐like ECH‐associated protein 1 (2011) (16)
- Conductive Adhesive Film Expands the Utility of Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging. (2019) (16)
- Inflammation and airway hyperresponsiveness after chlorine exposure are prolonged by Nrf2 deficiency in mice (2017) (16)
- A Histologic Categorization of Aqueous Outflow Routes in Familial Open-Angle Glaucoma and Associations With Mutations in the MYOC Gene in Japanese Patients. (2017) (15)
- Novel regulation of δ-aminolevulinate synthase in the rat harderian gland (1997) (15)
- Ribosome binding protein GCN1 regulates the cell cycle and cell proliferation and is essential for the embryonic development of mice (2020) (15)
- Inhibition of δ-aminolevulinic acid dehydratase by trichloroethylene (1984) (15)
- Structure and regulation of the chicken erythroid δ-aminolevulinate synthase gene (1994) (15)
- NRF2-Dependent Bioactivation of Mitomycin C as a Novel Strategy To Target KEAP1-NRF2 Pathway Activation in Human Cancer (2020) (15)
- GATA1 Binding Kinetics on Conformation-Specific Binding Sites Elicit Differential Transcriptional Regulation (2016) (15)
- Mouse Tryptase Gene Expression is Coordinately Regulated by GATA1 and GATA2 in Bone Marrow-Derived Mast Cells (2019) (15)
- Oral Azathioprine Leads to Higher Incorporation of 6-Thioguanine in DNA of Skin than Liver: The Protective Role of the Keap1/Nrf2/ARE Pathway (2011) (15)
- Hyperactivation of Nrf 2 in early tubular development induces nephrogenic diabetes insipidus (2017) (15)
- Nrf2 activation in myeloid cells and endothelial cells differentially mitigates sickle cell disease pathology in mice. (2019) (15)
- Extract of the mushroom Mycoleptodonoides aitchisonii induces a series of anti-oxidative and phase II detoxifying enzymes through activation of the transcription factor Nrf2 (2011) (15)
- Improved metabolomic data-based prediction of depressive symptoms using nonlinear machine learning with feature selection (2020) (15)
- Metabolomic Analysis of Mouse Brain after a Transient Middle Cerebral Artery Occlusion by Mass Spectrometry Imaging (2018) (15)
- Body mass index and colorectal cancer risk: A Mendelian randomization study (2021) (15)
- Protocol and Research Perspectives of the ToMMo Child Health Study after the 2011 Great East Japan Earthquake. (2015) (15)
- Transgenic over‐expression of GATA‐1 mutant lacking N‐finger domain causes hemolytic syndrome in mouse erythroid cells (2004) (14)
- GATA2‐dependent and region‐specific regulation of Gata2 transcription in the mouse midbrain (2009) (14)
- Nrf2 is activated by disruption of mitochondrial thiol homeostasis but not by enhanced mitochondrial superoxide production (2020) (14)
- Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy ( Proceedings of the National Academy of Sciences of the United States of America (2008) 105, 36, (13568-13573) DOI: 10.1073/pnas.0806268105) (2009) (13)
- Quantitative and qualitative impairments in GATA2 and myeloid neoplasms (2019) (13)
- Structure and regulation of the chicken GATA-3 gene. (1995) (13)
- Severity of eczema and mental health problems in Japanese schoolchildren: The ToMMo Child Health Study. (2018) (13)
- Effects of deficiency of Kelch‐like ECH‐associated protein 1 on skeletal organization: a mechanism for diminished nuclear factor of activated T cells cytoplasmic 1 during osteoclastogenesis (2017) (13)
- Nrf2 in toxicology and pharmacology: the good, the bad and the ugly? (2010) (13)
- Does k-11706 enhance performance and why? (2007) (13)
- An in vivo screening system to identify tumorigenic genes (2017) (12)
- Renal interstitial fibroblasts coproduce erythropoietin and renin under anaemic conditions (2020) (12)
- Nrf 2 protects against pulmonary fibrosis by regulating the lung oxidant level and Th 1 / Th 2 balance (2010) (12)
- Aryl Hydrocarbon Receptor Directly Regulates Artemin Gene Expression (2019) (12)
- In Vivo Spectrum of UVC‐induced Mutation in Mouse Skin Epidermis May Reflect the Cytosine Deamination Propensity of Cyclobutane Pyrimidine Dimers (2015) (12)
- Nuclear factor E2-related factor 2 (NRF2) deficiency accelerates fast fibre type transition in soleus muscle during space flight (2021) (12)
- Genome-wide analysis of polymorphism × sodium interaction effect on blood pressure identifies a novel 3′-BCL11B gene desert locus (2018) (12)
- Heme and heme biosynthesis intermediates induce heme oxygenase-1 and cytochrome P450 2A5, enzymes with putative sequential roles in heme and bilirubin metabolism: different requirement for transcription factor nuclear factor erythroid- derived 2-like 2. (2012) (12)
- Validation of multiple single nucleotide variation calls by additional exome analysis with a semiconductor sequencer to supplement data of whole-genome sequencing of a human population (2014) (12)
- Does Nrf2 gene transfer facilitate recovery after contusion spinal cord injury? (2014) (12)
- Involvement of the transcriptional factor GATA-1 in regulation of expression of coproporphyrinogen oxidase in mouse erythroleukemia cells. (1997) (12)
- Wavelength‐ and Tissue‐dependent Variations in the Mutagenicity of Cyclobutane Pyrimidine Dimers in Mouse Skin (2019) (12)
- Differential gene expression profiling between wild-type and ALAS2-null erythroblasts: identification of novel heme-regulated genes. (2006) (12)
- Metabolomic changes in the mouse retina after optic nerve injury (2018) (11)
- Functional characterization of 40 CYP2B6 allelic variants by assessing efavirenz 8‐hydroxylation (2018) (11)
- In Vivo Regulation of Erythropoiesis by Chemically Inducible Dimerization of the Erythropoietin Receptor Intracellular Domain (2015) (11)
- Chicken histone H3.3B cDNA sequence confirms unusual 3' UTR structure. (1987) (11)
- Effects of post-renal anemia treatment with the HIF-PHD inhibitor molidustat on adenine-induced renal anemia and kidney disease in mice. (2020) (11)
- Derepression of the DNA Methylation Machinery of the Gata1 Gene Triggers the Differentiation Cue for Erythropoiesis (2017) (11)
- Construction of JRG (Japanese reference genome) with single-molecule real-time sequencing (2019) (11)
- The Transcription Factor MAFF Regulates an Atherosclerosis Relevant Network Connecting Inflammation and Cholesterol Metabolism. (2021) (11)
- Efficient transient rescue of hematopoietic mutant phenotypes in zebrafish using Tol2‐mediated transgenesis (2010) (11)
- Metabolic basis of neuronal vulnerability to ischemia; an in vivo untargeted metabolomics approach (2020) (11)
- Nrf2 Activation Sensitizes K-Ras Mutant Pancreatic Cancer Cells to Glutaminase Inhibition (2021) (11)
- Regional genetic differences among Japanese populations and performance of genotype imputation using whole-genome reference panel of the Tohoku Medical Megabank Project (2018) (11)
- GATA2 hypomorphism induces chronic myelomonocytic leukemia in mice (2019) (10)
- Gata3 Hypomorphic Mutant Mice Rescued with a Yeast Artificial Chromosome Transgene Suffer a Glomerular Mesangial Cell Defect (2016) (10)
- Progenitor Stage-Specific Activity of a cis-Acting Double GATA Motif for Gata1 Gene Expression (2014) (10)
- Constitutive activation of the aryl hydrocarbon receptor in T-lineage cells induces thymus involution independently of the Fas/Fas ligand signaling pathway. (2006) (10)
- Verification of the in vivo activity of three distinct cis‐acting elements within the Gata1 gene promoter‐proximal enhancer in mice (2013) (10)
- Genome-wide association meta-analysis and Mendelian randomization analysis confirm the influence of ALDH2 on sleep durationin the Japanese population. (2019) (10)
- Syndecan 4 Mediates Nrf2-dependent Expansion of Bronchiolar Progenitors That Protect Against Lung Inflammation (2015) (10)
- A large cross-ancestry meta-analysis of genome-wide association studies identifies 69 novel risk loci for primary open-angle glaucoma and includes a genetic link with Alzheimer’s disease (2020) (10)
- 3.5KJPNv2, An allele frequency panel of 3,552 Japanese Individuals (2019) (10)
- Trans-ethnic Mendelian-randomization study reveals causal relationships between cardiometabolic factors and chronic kidney disease (2020) (10)
- Keap1 deletion accelerates mutant K-ras/p53-driven cholangiocarcinoma. (2020) (10)
- EVI1 and GATA2 misexpression induced by inv(3)(q21q26) contribute to megakaryocyte-lineage skewing and leukemogenesis. (2020) (10)
- A core region of the mafK gene IN promoter directs neurone‐specific transcription in vivo (1998) (10)
- Maternal Baseline Characteristics and Perinatal Outcomes: The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study (2020) (10)
- Production of IL-17A at Innate Immune Phase Leads to Decreased Th1 Immune Response and Attenuated Host Defense against Infection with Cryptococcus deneoformans (2020) (10)
- Identification and Validation of Combination Plasma Biomarker of Afamin, Fibronectin and Sex Hormone-Binding Globulin to Predict Pre-eclampsia. (2021) (10)
- Dysfunction of Nrf2 decreases KBrO3-induced oxidative DNA damage in Ogg1-null mice. (2007) (10)
- An insulin-like growth factor II-producing histiocytoma associated with hypoglycemia: analysis of the peptide, its gene expression, and glucose transporter isoforms. (1992) (10)
- Nrf2 Antioxidative System is Involved in Cytochrome P450 Gene Expression and Activity: A Delay in Pentobarbital Metabolism in Nrf2-Deficient Mice (2020) (9)
- GATA transcription factors negatively regulate erythropoietin gene expression. (1996) (9)
- Outlier detection for questionnaire data in biobanks. (2019) (9)
- Construction of full-length Japanese reference panel of class I HLA genes with single-molecule, real-time sequencing (2018) (9)
- Constitutively active aryl hydrocarbon receptor expressed in T cells increases immunization-induced IFN-gamma production in mice but does not suppress T(h)2-cytokine production or antibody production. (2009) (9)
- The anemia of the newborn induces erythropoietin expression in the developing mouse retina. (2010) (9)
- Exome sequencing deciphers a germline MET mutation in familial epidermal growth factor receptor‐mutant lung cancer (2017) (9)
- Intracellular S1P Levels Dictate Fate of Different Regions of the Hippocampus following Transient Global Cerebral Ischemia (2018) (9)
- Maternity Log study: a longitudinal lifelog monitoring and multiomics analysis for the early prediction of complicated pregnancy (2019) (9)
- One-year trajectories of postpartum depressive symptoms and associated psychosocial factors: findings from the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. (2021) (9)
- The isoquinoline PRL-295 increases the thermostability of Keap1 and disrupts its interaction with Nrf2 (2021) (9)
- Preconditioning the immature lung with enhanced Nrf2 activity protects against oxidant-induced hypoalveolarization in mice (2020) (9)
- Efficacy estimation of erythropoiesis-stimulating agents using erythropoietin-deficient anemic mice (2016) (9)
- Cellular Nrf2 Levels Determine Cell Fate during Chemical Carcinogenesis in Esophageal Epithelium (2020) (9)
- Identification of critical genetic variants associated with metabolic phenotypes of the Japanese population (2020) (8)
- Distinct Regulations of HO-1 Gene Expression for Stress Response and Substrate Induction (2021) (8)
- Erratum: Small Maf proteins heterodimerize with fos and may act as competitive repressors of the NF-E2 transcription factor (Molecular and Cellular Biology (1995) 15:5 (2188)) (1995) (8)
- Regulatory Role of the COX-2 Pathway in the Nrf2-Mediated Anti-Inflammatory Response (2005) (8)
- Molecular defect in human erythropoietic protoporphyria with fatal liver failure (1993) (8)
- Nrf2 Regulates the Risk of a Diesel Exhaust Inhalation-Induced Immune Response during Bleomycin Lung Injury and Fibrosis in Mice (2017) (8)
- Machine learning for effectively avoiding overfitting is a crucial strategy for the genetic prediction of polygenic psychiatric phenotypes (2020) (8)
- Lipopolysaccharide-induced expansion of histidine decarboxylase-expressing Ly6G+ myeloid cells identified by exploiting histidine decarboxylase BAC-GFP transgenic mice (2019) (8)
- A genotype imputation method for de-identified haplotype reference information by using recurrent neural network (2020) (8)
- A Gata3 3′ Distal Otic Vesicle Enhancer Directs Inner Ear-Specific Gata3 Expression (2018) (8)
- GATA1 and GATA2 Function in Hematopoietic Differentiation (2010) (8)
- Development and application of a rapid and sensitive genotyping method for pharmacogene variants using the single-stranded tag hybridization chromatographic printed-array strip (STH-PAS). (2018) (8)
- Genetic evidence of PEBP2β-independent activation of Runx1 in the murine embryo (2008) (8)
- Hypertensive disorders of pregnancy, obesity, and hypertension in later life by age group: a cross-sectional analysis (2020) (8)
- Monitoring of minimal residual disease in early T‐cell precursor acute lymphoblastic leukaemia by next‐generation sequencing (2017) (8)
- Japonica Array NEO with increased genome-wide coverage and abundant disease risk SNPs (2020) (7)
- Nrf2 expression in pancreatic stellate cells promotes progression of cancer. (2021) (7)
- Large scale genome-wide association study in a Japanese population identified 45 novel susceptibility loci for 22 diseases (2019) (7)
- The role of nuclear factor E2-Related factor 2 and uncoupling protein 2 in glutathione metabolism: Evidence from an in vivo gene knockout study. (2016) (7)
- Association of single nucleotide polymorphisms in the NRF2 promoter with vascular stiffness with aging (2020) (7)
- Spiral ganglion cell degeneration‐induced deafness as a consequence of reduced GATA factor activity (2019) (7)
- Selective isotope labeling of recombinant proteins in Escherichia coli. (2012) (7)
- A low-frequency IL4R locus variant in Japanese patients with intravenous immunoglobulin therapy-unresponsive Kawasaki disease (2019) (6)
- Nrf2 Activation Ameliorates Hepatotoxicity Induced by a Heme Synthesis Inhibitor (2018) (6)
- A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids (2021) (6)
- Protracted rosiglitazone treatment exacerbates inflammation in white adipose tissues of adipocyte-specific Nfe2l1 knockout mice. (2020) (6)
- Novel candidates of pathogenic variants of the BRCA1 and BRCA2 genes from a dataset of 3,552 Japanese whole genomes (3.5KJPNv2) (2021) (6)
- An erythroid to myeloid cell fate conversion is elicited by LSD1 inactivation. (2021) (6)
- GATA 2 is critical for the maintenance of cellular identity in differentiated mast cells derived from mouse bone marrow (2015) (6)
- Stem cells of GATA1-related leukemia undergo pernicious changes after 5-fluorouracil treatment. (2009) (6)
- Generation and Molecular Characterization of Human Ring Sideroblasts: a Key Role of Ferrous Iron in Terminal Erythroid Differentiation and Ring Sideroblast Formation (2018) (6)
- The Human GATA1 Gene Retains a 5′ Insulator That Maintains Chromosomal Architecture and GATA1 Expression Levels in Splenic Erythroblasts (2015) (6)
- Genetic ablation of Nrf2 exacerbates neurotoxic effects of acrylamide in mice. (2021) (6)
- Erratum: GATA motifs regulate early hematopoietic lineage-specific expression of the Gata2 gene (Molecular and Cellular Biology (2005) 25, 16 (7005-7020)) (2005) (6)
- The return of individual genomic results to research participants: design and pilot study of Tohoku Medical Megabank Project (2021) (6)
- Isolation and characterization of zebrafish NFE 2 (2002) (5)
- Nrf2 Lowers the Risk of Lung Injury via Modulating the Airway Innate Immune Response Induced by Diesel Exhaust in Mice (2020) (5)
- GATA2 and PU.1 Collaborate To Activate the Expression of the Mouse Ms4a2 Gene, Encoding FcεRIβ, through Distinct Mechanisms (2019) (5)
- Novel regulation of delta-aminolevulinate synthase in the rat harderian gland. (1997) (5)
- Osteoclasts adapt to physioxia perturbation through DNA demethylation (2021) (5)
- Oral Microbiome Analysis in Prospective Genome Cohort Studies of the Tohoku Medical Megabank Project (2021) (5)
- Two effects of GATA2 enhancer repositioning by 3q chromosomal rearrangements (2019) (5)
- Genome-wide association study identifies new loci for albuminuria in the Japanese population (2020) (5)
- Estimating carrier frequencies of newborn screening disorders using a whole-genome reference panel of 3552 Japanese individuals (2019) (5)
- Dimethyl Fumarate Suppresses Inflammation In Vitro Via Both Nrf2-Dependent and Nrf2-Independent Pathways (P02.108) (2012) (5)
- Discovery of an NRF1‐specific inducer from a large‐scale chemical library using a direct NRF1‐protein monitoring system (2015) (5)
- A training and education program for genome medical research coordinators in the genome cohort study of the Tohoku Medical Megabank Organization (2019) (5)
- New insights into nuclear factor erythroid 2-related factors in toxicology and pharmacology. (2019) (5)
- Nerve growth factor-regulated properties of sensory neurones in Oct-2 null mutant mice. (1995) (5)
- Hematological aspects of a novel 9‐aminoanthracycline, amrubicin (2003) (5)
- Author Correction: Nrf2 contributes to the weight gain of mice during space travel (2020) (4)
- Infiltration of M 1 , but not M 2 , macrophages is impaired after unilateral ureter obstruction in Nrf 2-deficient mice (2017) (4)
- Possible Roles of Proinflammatory Signaling in Keratinocytes Through Aryl Hydrocarbon Receptor Ligands for the Development of Squamous Cell Carcinoma (2020) (4)
- Nrf2 plays a critical role in the metabolic response during and after spaceflight (2021) (4)
- Hypoxia-sensitive reporter system for high-throughput screening. (2015) (4)
- Structure and chromosome mapping of the human small maf genes MAFG and MAFK (1998) (4)
- Machine learning approaches to predict gestational age in normal and complicated pregnancies via urinary metabolomics analysis (2021) (4)
- Erratum: Glutathione peroxidase 2, the major cigarette smoke-inducible isoform of GPX in lungs, is regulated by Nrf2 (American Journal of Respiratory Cell and Molecular Biology (2006) 35 (639-650)) (2007) (4)
- Nrf2-mediated protection against angiotensin II-induced cardiac hypertrophy (2011) (4)
- Structure and regulation of vertebrate δ‐aminolevulinate synthases (1994) (4)
- Nrf2 deficiency deteriorates diabetic kidney disease in Akita model mice (2022) (4)
- Hematopoietic stem and progenitor cell activation during chronic dermatitis provoked by constitutively active aryl-hydrocarbon receptor driven by Keratin 14 promoter. (2014) (4)
- Wide-Targeted Metabolome Analysis Identifies Potential Biomarkers for Prognosis Prediction of Epithelial Ovarian Cancer (2021) (4)
- Genetic loci for lung function in Japanese adults with adjustment for exhaled nitric oxide levels as airway inflammation indicator (2021) (4)
- Induction of erythropoietin gene expression in epithelial cells by chemicals identified in GATA inhibitor screenings (2017) (4)
- Establishment of erythroleukemic GAK14 cells and characterization of GATA1 N‐terminal domain (2013) (4)
- Differential induction responses of δ‐aminolevulinate synthase mRNAs during erythroid differentiation: Use of nonradioactive in situ hybridization (1992) (4)
- NRF2-Mediated Gene Regulation and Glucose Homeostasis (2016) (4)
- [Renal erythropoietin-producing cells and kidney disease]. (2014) (4)
- Identification of Dominant Transcripts in Oxidative Stress Response by a Full-Length Transcriptome Analysis (2020) (4)
- Analysis of HLA-G long-read genomic sequences in mother–offspring pairs with preeclampsia (2020) (4)
- Differential Regulation of 5-Aminolevulinate Synthase Isozymes in Vertebrates (2013) (4)
- Structural instability of IκB kinase β promotes autophagic degradation through enhancement of Keap1 binding (2018) (3)
- Erythropoietin in myoblast maintenance and muscle regeneration (2008) (3)
- Erratum: The flavanol (-)-epicatechin prevents stroke damage through the Nrf2/HO1 pathway (Journal of Cerebral Blood Flow and Metabolism (2014) 34 (735) DOI: 10.1038/jcbfm.2014.10) (2014) (3)
- Gata3 hypomorphic mutant mice rescued with a YAC transgene suffer a glomerular mesangial cell defect (2016) (3)
- Correction: Tissue-Restricted Expression of Nrf2 and Its Target Genes in Zebrafish with Gene-Specific Variations in the Induction Profiles (2012) (3)
- dbTMM: an integrated database of large-scale cohort, genome and clinical data for the Tohoku Medical Megabank Project (2021) (3)
- Landscape of electrophilic and inflammatory stress-mediated gene regulation in human lymphoblastoid cell lines. (2020) (3)
- Defining the functionally sufficient regulatory region and liver-specific roles of the erythropoietin gene by transgene complementation. (2021) (3)
- dbTMM: an integrated database of large-scale cohort, genome and clinical data for the Tohoku Medical Megabank Project (2021) (3)
- Comparison of Kit-Based Metabolomics with Other Methodologies in a Large Cohort, towards Establishing Reference Values (2021) (3)
- The Keap1-Nrf2 pathway: From mechanism to medical applications (2020) (3)
- Halofuginone micelle nanoparticles eradicate Nrf2-activated lung adenocarcinoma without systemic toxicity. (2022) (3)
- [Structure and tissue-specific expression of erythroid type delta-aminolevulinate synthase: relation to erythroid-specific transcription factors]. (1992) (3)
- Heart Rate Information-Based Machine Learning Prediction of Emotions Among Pregnant Women (2022) (3)
- Transgenic Expression of Bach1 Transcription Factor Results in Down-Regulation of the p45 Target Genes in Megakaryocytic Lineage Cells. (2004) (3)
- Effects of in vivo deletion of GATA2 in bone marrow stromal cells. (2017) (3)
- Oxidative-stress-driven mutagenesis in the small intestine of the gpt delta mouse induced by oral administration of potassium bromate. (2020) (3)
- Role of Nrf 2 in retinal vascular development and the vaso-obliterative phase of oxygen-induced retinopathy (2016) (3)
- Combined Associations of Body Mass Index and Metabolic Health Status on Medical and Dental Care Days and Costs in Japanese Male Employees: A 4-Year Follow-Up Study (2019) (3)
- Corrigendum to “Runx1 is involved in the fusion of the primary and the secondary palatal shelves” [Dev. Biol. 326 (2009) 392–402] (2009) (3)
- Design and Progress of Oral Health Examinations in the Tohoku Medical Megabank Project. (2020) (3)
- Dietary supplementation with sulforaphane attenuates liver damage and heme overload in a sickle cell disease murine model. (2019) (3)
- CL316243 treatment mitigates the inflammation in white adipose tissues of juvenile adipocyte-specific Nfe2l1 knockout mice. (2021) (2)
- Interethnic analyses of blood pressure loci in populations of East Asian and European descent (2018) (2)
- Low birth weight and abnormal pre-pregnancy body mass index were at higher risk for hypertensive disorders of pregnancy. (2020) (2)
- Construction of full-length Japanese reference panel of class I HLA genes with single-molecule, real-time sequencing (2018) (2)
- [Molecular mechanism of adaptive response to electrophiles]. (2004) (2)
- Molecular Evolution of Keap 1 : Two Keap 1 Molecules with Distinctive IVR Structures are Conserved among Fish (2008) (2)
- , the BTB / POZ Domain and MAZR ( MAZ-Related Factor ) through Generated by Transcription Factor Bach 2 A Combinatorial Code for Gene Expression (1999) (2)
- NRF 2 TRANSACTIVATOR-INDEPENDENT GST-P1-1 POSITIVE SINGLE CELLS IN FEMALE MOUSE LIVER BY DEN: A PRENEOPLASTIC CHARACTER OF POSSIBLE INITIATED CELLS (2002) (2)
- Correction: Transcript Profiling Identifies Dynamic Gene Expression Patterns and an Important Role for Nrf2/Keap1 Pathway in the Developing Mouse Esophagus (2012) (2)
- 767: NRF2 is Essential for the Chemopreventive Efficacy of Oltipraz Against Urinary Bladder Carcinogenesis (2005) (2)
- Erratum: Differential responses of the Nrf2-Keap1 system to laminar and oscillatory shear stresses in endothelial cells (Journal of Biological Chemistry (2005) 280 (27244-27250)) (2005) (2)
- Summary Characterization of the pufferfish Otx 2 cis-regulators reveals evolutionarily conserved genetic mechanisms for vertebrate head specification (2003) (2)
- GATA Motif on the Erythropoietin Gene Promoter Is Essential for Repression of Ectopic Constitutive Erythropoietin Production. (2005) (2)
- The subcellular localization and activity of cortactin is regulated by acetylation and interaction with Keap 1 (2015) (2)
- Do β-globin, GATA-1, or EpoR regulatory domains specifically mark erythroid progenitors in transgenic reporter mice?. Authors' reply (2004) (2)
- Fractionation of mature eosinophils in GATA-reporter transgenic mice. (2010) (2)
- [Function and gene expression regulation of GATA-1 and GATA-2 transcription]. (2007) (2)
- An immunochemical study of delta-aminolevulinate synthase and delta-aminolevulinate dehydratase in liver and erythroid cells of rat. (1986) (2)
- Structure and regulation of the chicken erythroid delta-aminolevulinate synthase gene. (1994) (2)
- Amino-acid selective isotope labeling enables simultaneous overlapping signal decomposition and information extraction from NMR spectra (2020) (2)
- CNC-bZIP protein NFE2L1 regulates osteoclast differentiation in antioxidant-dependent and independent manners (2021) (2)
- Trans-ethnic Mendelian-randomization study reveals causal relationships between cardiometabolic factors and chronic kidney disease. (2021) (2)
- A Pilot Study for Return of Individual Pharmacogenomic Results to Population-Based Cohort Study Participants (2022) (2)
- Renal NG2-expressing cells have macrophage-like phenotype and facilitate renal recovery after ischemic injury. (2021) (2)
- Organic synthesis and anti-influenza A virus activity of cyclobakuchiols A, B, C, and D (2021) (2)
- Detection of novel metabolite for roxadustat doping by global metabolomics. (2018) (2)
- [Structure and function of GATA transcription factors; possible roles in cell differentiation]. (1994) (1)
- Construction and integration of three de novo Japanese human genome assemblies toward a population-specific reference (2021) (1)
- Association between glycemic traits and primary open-angle glaucoma: A Mendelian randomization study in the Japanese population. (2022) (1)
- Leukemogenesis in Down syndrome (2015) (1)
- Forced HoxB4 Sustains CD45 - c-kit + Pre-Hematopoieitc Stem Cells (HSCs) Derived from Murine Induced-Pluripotent Stem Cells, Which Develop Long-Term and Short-Term Repopulating HSCs According to GATA2 Expression Level (2014) (1)
- Abstract LB-174: Genome-wide association meta-analysis identifies novelGP2gene risk variants for pancreatic cancer in the Japanese population (2019) (1)
- Molecular basis of Keap1-Nrf2 system function (2012) (1)
- Keap 1 knockdown increases markers of metabolic syndrome after long-term fat diet feeding (2013) (1)
- mafB Deficient Mouse Results in Impaired Macrophage Differentiation. (2005) (1)
- Heterozygous variants in GATA2 contribute to DCML deficiency in mice by disrupting tandem protein binding (2022) (1)
- Effect of prenatal antioxidant sulforaphane on fetal transcriptomics in mice (2013) (1)
- Corrigendum to "Nrf2 deficiency aggravates the increase in osteoclastogenesis and bone loss induced by inorganic arsenic" [Toxicology and applied pharmacology 367 (2019) 62-70]. (2021) (1)
- Author Correction: Characterizing rare and low-frequency height-associated variants in the Japanese population (2020) (1)
- Familial Paget’s disease of bone with ocular manifestations and a novel TNFRSF11A duplication variant (72dup27) (2022) (1)
- Genome-wide Association Study of Axial Length in Population-based Cohorts in Japan (2022) (1)
- Blockade of the interaction between BMP9 and endoglin on erythroid progenitors promotes erythropoiesis in mice (2021) (1)
- Molecular Determinants for Small Maf Protein Control of Platelet Production (2012) (1)
- Estimation of the carrier frequencies and proportions of potential patients by detecting causative gene variants associated with autosomal recessive bone dysplasia using a whole-genome reference panel of Japanese individuals (2021) (1)
- Respiratory resistance among adults in a population-based cohort study in Northern Japan. (2019) (1)
- Target Gene Diversity of the Nrf1-MafG Transcription Factor Revealed by a Tethered Heterodimer (2022) (1)
- Construction of a trio-based structural variation panel utilizing activated T lymphocytes and long-read sequencing technology (2022) (1)
- Correction: Disruption of Nrf2 Impairs the Resolution of Hyperoxia-Induced Acute Lung Injury and Inflammation in Mice (2017) (1)
- 3.5KJPNv2: an allele frequency panel of 3552 Japanese individuals including the X chromosome (2019) (1)
- Esterification promotes the intracellular accumulation of roxadustat, an activator of hypoxia-inducible factors, to extend its effective duration. (2022) (1)
- A Recurrent Neural Network Based Method for Genotype Imputation on Phased Genotype Data (2019) (1)
- Long-Term Ex Vivo Maintenance Of Murine iPSC-Derived Hematopoietic Stem/Progenitor Cells By Conditional HoxB4 (2013) (1)
- Gut microbiome-derived phenyl sulfate contributes to albuminuria in diabetic kidney disease (2019) (1)
- Molecular mechanisms of Nrf2-Keap1 response against oxidative and electrophilic stresses (2006) (1)
- Pathogenic mutations identified by a multimodality approach in 117 Japanese Fanconi anemia patients (2020) (1)
- [Network regulation of Gata1 and Gata2 gene-dynamics underlies erythroid differentiation]. (2014) (1)
- Regional genetic differences among Japanese populations and performance of genotype imputation using whole-genome reference panel of the Tohoku Medical Megabank Project (2018) (1)
- The epigenetic eraser LSD1 lies at the apex of a reversible erythroid to myeloid cell fate decision (2021) (1)
- Chronicity of Immune Abnormality in Atopic Dermatitis: Interacting Surface Between Environment and Immune System (2016) (1)
- [CNC-small Maf heterodimer: Unique cis-element recognition and biological functions]. (2017) (1)
- Nrf2 is activated by disruption of mitochondrial thiol homeostasis but not by enhanced mitochondrial superoxide production. (2020) (1)
- OS 05-05 Nrf2 DEFICIENCY ALLEVIATES PERINATAL COMPLICATIONS IN PREGNANCY-ASSOCIATED HYPERTENSION MICE VIA ENHANCING PLACENTAL ANGIOGENESIS (2016) (1)
- Validation of multiple single nucleotide variation calls by additional exome analysis with a semiconductor sequencer to supplement data of whole-genome sequencing of a human population (2014) (1)
- GWAS Identified IL4R and the Major Histocompatibility Complex Region as the Associated Loci of Total Serum IgE Levels in 9,260 Japanese Individuals (2021) (1)
- Combining MRI and genetic data in the Tohoku Medical Megabank Organization cohort study for innovative Alzheimer’s disease research (2020) (1)
- Longitudinal plasma amino acid profiling with maternal genomic background throughout human pregnancy (2020) (1)
- Keap1-Nrf2 Regulatory System and Cancer (2015) (1)
- Keap1-Nrf2 System: Potential Role in Prevention of Sickle Cell Disease Organs Damages and Inflammation (2015) (1)
- GATA2 haploinsufficiency accelerates EVI-1-driven leukemogenesis in an inv(3)(q21q26) mouse model (2019) (0)
- mouse embryos differentiation of the hematopoietic precursor cells in midgestation Expression and domain-specific function of GATA-2 during (2013) (0)
- Abstract 15037: Novel Role of Kelch-like ECH-associated Protein 1/NF-E2-related Factor 2 System in Vascular Smooth Muscle Cell Apoptosis Following Vascular Injury (2014) (0)
- OS 05-05 Nrf2 DEFICIENCY ALLEVIATES PERINATAL COMPLICATIONS IN PREGNANCY-ASSOCIATED HYPERTENSION MICE VIA ENHANCING PLACENTAL ANGIOGENESIS. (2016) (0)
- , for Mast Cell Differentiation in Adult Mice Transcription Factor GATA 1 Is Dispensable (2014) (0)
- Nrf2 Deficiency Exacerbates Bronchopulmonary Dysplasia Phenotypes Induced by Hyperoxia in Developing Lung. (2009) (0)
- Discovery of Environmental Stress Response Mechanisms and Deciphering Their Essential Roles in Human Health and Diseases (2017) (0)
- Differential responses of the Nrf2-Keap1 system to laminar and oscillatory shear stresses in endothelial cells. VOLUME 280 (2005) PAGES 27244-27250 (2005) (0)
- Roles of P21(WAF1) and P27(KIP1) in GATA-2-induced growth suppression of hematopoietic cells. (2001) (0)
- Transcription factor regulation of drug metabolizing enzymes and antioxidant proteins(the symposium 1 "Molecular Mechanism of biological responses toward environmental pollutants" at the 32nd JEMS annual meeting, 2003.) (2004) (0)
- genomic coordinates of the mouse CAGE peaks (2017) (0)
- Nrf2 lowers risk for lung injury induced by diesel exhaust (2014) (0)
- Isolation and Characterization of Renal Erythropoietin-Producing Cells: Contribution of HIF3α In Vivo. (2010) (0)
- Detection of Hypoxia-Inducible Gene Manipulation. (2007) (0)
- Contribution of Gata2 haploinsufficiency to leukemia with 3q chromosomal rearrangements (2017) (0)
- Enhanced resistance to oxidative lung injury by an Nrf2‐ARE inducer in mice (2008) (0)
- embryogenesis activity of fetal liver kinase (Flk)-1 promoter/enhancer during mouse Hemogenic and non-hemogenic endothelium can be distinguished by the (2013) (0)
- B cell development is influenced by expression of Gata1 (2017) (0)
- Title Loss of a Rho-Regulated Actin Nucleator , mDia 2 , ImpairsCytokinesis during Mouse Fetal Erythropoiesis (2018) (0)
- GATA1 Mutants Lacking Rb-Binding Motif Observed in Transient Abnormal Myelopoiesis in Down Syndrome (2011) (0)
- Editor's/Publisher's Disclaimer (1998) (0)
- 2-Oxoglutarate Down-Regulates Expression of Vascular Endothelial Growth Factor and Erythropoietin through Decreasing Hypoxia Inducible Factor-1 α and Inhibits Angiogenesis. (2005) (0)
- transcription factor encoded by the mi locus Regulation of mouse mast cell protease 6 gene expression by (2011) (0)
- INDUCIBLE EXPRESSION OF ANTOXIDANT AND DETOXICATION ENZYMES AS A MECHANISM OF CANCER CHEMOPREVENTION (2000) (0)
- TBE31 activates Nrf2 via Keap1 Cys151 and suppresses inflammation (2017) (0)
- Aim and Progress of Tohoku Medical Megabank Project (2019) (0)
- Expression, purification and binding to the receptor of human insulin-like growth factor II. (1993) (0)
- Lineage commitment (WS-033) Chairpersons: Hiroshi Kawamoto, Koji Yasutomo (2010) (0)
- Gata3 hypomorphic mutant mice with YAC-transgenic partial rescue suffer glomerular mesangial cell defect (2016) (0)
- -globin LCR luciferase transgenic mice β Real-time monitoring of stress erythropoiesis in vivo using Gata1 and (2013) (0)
- Simultaneous Activation of K-ras and NRF2 Induce Pancreatic Atrophy (2017) (0)
- The synthetic triterpenoid CDDO-Im modulates pathways beyond Keap1-Nrf2 signaling at doses relevant to chemoprevention (2007) (0)
- Suppression of autophagy causes metabolic and transcriptional reprogramming (2015) (0)
- Nrf2 induction by oral administration of glucoraphanin relives tissue damage in sickle cell disease (2017) (0)
- 108 NRF2 Prevents Alcohol Induced Fulminant Liver Injury (2008) (0)
- Compound deficiency of Nrf2 and selenoproteins in hematopoietic cells leads to severe defects in erythroid and lymphoid lineage development (2010) (0)
- [Flies, fishes and frogs turn the tide of hematopoietic research]. (2005) (0)
- Crystal structure of MafG-DNA complex (2009) (0)
- and Aorta-Gonads and Mesonephros Region The Mouse GATA-2 Gene is Expressed in the Para-Aortic Splanchnopleura (2013) (0)
- RESULTS Upregulation of Nrf 2 target genes in the kidneys of mice subjected to ischemia – reperfusion Using (2009) (0)
- Protective role of NRF2 in hepatic carcinogenesis (2018) (0)
- Metabolism of 8-nitro-cGMP and regulation of electrophilic signaling by reactive sulfur species (2014) (0)
- Supplemental Information Low-Dose Irradiation Promotes Persistent Oxidative Stress and Decreases Self-Renewal in Hematopoietic Stem Cells (2017) (0)
- A stress-responsive transcriptional factor NRF2 activates hematopoietic stem cells (2015) (0)
- Investigating The Therapeutic Potential Of Nrf2 Wild-Type And Nrf2-Deficient Mesenchymal Stem Cells In Elastase Induced Pulmonary Emphysema (2011) (0)
- Disruption of Nrf2 enhances susceptibility to pulmonary fibrosis induced by bleomycin in mice (2011) (0)
- Evaluation of interactions between DNA and transcription factors by surface plasmon resonance imaging technique (2006) (0)
- PHAGOCYTES , GRANULOCYTES , AND MYELOPOIESIS GATA 2 is critical for the maintenance of cellular identity in differentiated mast cells derived from mouse bone marrow (2015) (0)
- Air pollution activates Aryl hydrocarbon receptor in murine epidermis, leading to Atopic dermatitis-like pathologies (2017) (0)
- Detection of novel metabolite for Roxadustat doping by global metabolomics. (2018) (0)
- Transcriptional regulation of megakaryopoiesis and thrombopoiesis (2012) (0)
- NRF2 activation induces cancer-related inflammation and malignancy of Kras-induced lung tumors (2017) (0)
- Nrf2 Knockout Mice that Lack Control of Drug Metabolizing and Antioxidant Enzyme Genes - Animals Highly Sensitive to Xenobiotic Toxicity (2001) (0)
- [Function, molecular structure and gene expression of insulin-like growth factors ]. (1992) (0)
- sample information of the human samples (2017) (0)
- AGAINST OXIDATIVE STRESS IN AD : INDUCTION OF THE NRF 2-ARE PATHWAY (2011) (0)
- Role of the redox-sensitive transcription factor Nrf2 in vascular smooth muscle cell migration and vascular remodeling (2012) (0)
- LSD 1 / KDM 1 A promotes hematopoietic commitment of hemangioblasts through downregulation of Etv 2 (2016) (0)
- NRF2-Deficient Mice following Hyperoxia Exposure Is Impaired in Innate Immunity against Bacterial Infection (2009) (0)
- Regulatory mechanism of neointimal formation after vascular injury by transcription factor Nrf2 via inhibiting ROS—ERK pathway (2013) (0)
- [9th symposium on bacterial toxins. 1. On the mechanism of action of toxins. B. Cellular level. 4. On the mechanism of toxic action of diphtheria toxin on Ehrlich ascites tumor cells]. (1962) (0)
- DNA Binding Diversity Achieved Through the Interaction of GATA1 N-Finger and GATA Motif Is Important for Embryonic Erythropoiesis (2012) (0)
- Publisher Correction: Enhancer remodeling promotes tumor-initiating activity in NRF2-activated non-small cell lung cancers (2021) (0)
- The KEAP1-NRF2 System for Understanding of Diseases and Drug Development (2018) (0)
- Development of Novel Inhibitors for Keap1-Nrf2 and Keap1-P62 Protein-Protein Interaction (2016) (0)
- Structural and Functional Study for Keap1-Nrf2 complex by 19F-NMR (2016) (0)
- TAL-1 and GATA-1 coupled cell proliferation and differentiation during terminal erythroid differentiation (2007) (0)
- P8-26 Oxidaive/proteolytic activation of membrane-bound glutathione S-transferase in galactosamine/lipopolysaccharide-treated rats(CIRCULATORY SYSTEM-2/ACTIVE OXYGEN)(GENERAL SESSION BY POSTER PRESENTATION)(Proceedings of the 31st Annual Meeting) (2004) (0)
- SAT-116 A CELL LINE DERIVED FROM RENAL ERYTHROPOIETIN-PRODUCING CELLS PROVES THEIR MYOFIBROBLAST-TRANSFORMATION PROPERTY (2019) (0)
- Nrf2 Inhibits Lipopolysaccharide-Induced IL-6 Secretion in RAW Macrophage Cell Line. (2009) (0)
- Deficiency Of Nrf2 Enhances Sensitivity To Naphthalene Induced Toxicity And Impairs Bronchiolar Epithelial Repair (2010) (0)
- 785 NRF2 Knockout Suppresses Pancreatic Carcinogenesis in a Mouse Model (2016) (0)
- GATA2 (GATA binding protein 2) (2018) (0)
- O68. Physiological role of Keap1 S-guanylation by 8-nitroguanosine 3′,5′-cyclic monophosphate formed in C6 glioma cells (2008) (0)
- [111th Scientific Meeting of the Japanese Society of Internal Medicine: Panel Discussion: Internal medicine creating future health care: 4. Tohoku Medical Megabank Project and future medicine]. (2014) (0)
- Dimerisation of adaptor protein Keap1 is required to correctly position Nrf2 for ubiquitylation upon the Cul3‐Rbx1 holoenzyme: the ‘fixed‐ends’ model (2007) (0)
- Abstract 316: Keap1 and Nrf2 genetic mutations and polymorphisms: Associations with clinical outcome in endometrial cancer (2011) (0)
- Compound Deficiency of Nrf2 and Selenoproteins in Hematopoietic Cells Leads to Severe Defects in Erythroid and Lymphoid Lineage Development. (2009) (0)
- Essential Role and Regulatory Mechanism of the Erythropoietin Gene in the Liver. (2005) (0)
- [HCV gene transfected animal using receptor mediated gene delivery]. (1995) (0)
- Erratum: Environmental Electrophile-Mediated Toxicity in Mice Lacking Nrf2, CSE, or Both (2020) (0)
- Abstract 49: The Transcriptional Repressor MafG Regulates Cholesterol Catabolism (2015) (0)
- The Critical Function of c-Myb and CD9 On Megakaryopoiesis. (2009) (0)
- ACTIVATION OF KEAP1-NRF2 SYSTEM MITIGATES OXIDATIVE STRESS AND NEUROINFLAMMATION IN THE ALZHEIMER'S DISEASE MODEL (2019) (0)
- The Keap1-Nrf2 system prevents oxidative damage in pancreatic β-cells and hypothalamus of Trsp-depleted mice (2015) (0)
- Mechanism for the protective effect of pyrrolidine dithiocarbamate against oxidative stress in AD: induction of the Nrf2-ARE pathway (2011) (0)
- genomic coordinates of the human CAGE peaks (2017) (0)
- expression table of the human CAGE peaks (2017) (0)
- Discovery of the KEAP1-NRF2 pathway regulating cellular response against oxidative and electrophilic stresses (2021) (0)
- Loss of p62/SQSTM1 but not Nrf2 accelerates motor neuron degeneration in SOD1 H46R transgenic mice (2015) (0)
- Impact of Nrf2 on pancreatic carcinogenesis in mice (2016) (0)
- Ubiquitin-Proteasome-Dependent Degradation of GATA-2 and Its Contribution to the UV-C-Induced Down-Regulation. (2004) (0)
- Nuclear Factor Erythroid-Derived 2-like 2 Enhances Cell Proliferation and Resistance to Anti-Cancer Cisplatin in Human Lung Cancer Cells. (2009) (0)
- Cysteine rich domain of TET2 protein as a reader of histone H3 K36 mono and di methylation (2016) (0)
- Subject Index Vol. 95, 1996 (1996) (0)
- A Biological Sensor for Protection against Oxidative Stress : Keap1-Nrf2 System (2007) (0)
- IM6 BONE MARROW RECONSTITUTION OF ERYTHROPOIESIS AND IMMUNE RESPONSE FOLLOWING γ-IRRADIATION IN THE MICE.(Immunology)(Proceedings of the Fifty-Fifth Annual Meeting of the Zoological Society of Japan) (1984) (0)
- Murine embryos bearing an inactivating targeted deletion of gata 2 in the germline die (0)
- Physiological roles of AhR in murine reproductive and immunological processes (2006) (0)
- Anemia causes hypotension and enhances renal expression of the renin gene (2017) (0)
- c-Myb Regulates CD9 Gene Expression during Megakaryopoiesis. (2007) (0)
- Activation of Nrf–2 in hereditary tyrosinemia type 1 and its role in survival and hepatocarcinogenesis (2008) (0)
- Spherocytic Hemolytic Anemia Caused by Disruption of GATA1-FOG1 Interaction. (2009) (0)
- Leukemia-Related Transcription Factor TEL Expands Erythroid Precursors. (2007) (0)
- How KEAP1 Deletion in Single Cell Mitigates Sickle Cell Pathology (2018) (0)
- Crystal Structure of Keap1 in Complex with the N-terminal region of the Nrf2 transcription factor (2013) (0)
- myeloid leukemia chimeric gene in t(8;21)(q24;q22) acute AML1-TRPS1 factors by the Concurrent transcriptional deregulation of AML1/RUNX1 and GATA (2008) (0)
- Crystal Structure of Keap1 in Complex with a small chemical compound, K67 (2016) (0)
- GATA 2 haploinsufficiency accelerates EVI 1-driven leukemogenesis Running title : GATA 2 haploinsufficiency in 3 q AML (2017) (0)
- Abstract 3486: Body mass index and colorectal cancer risk in Japanese populations: a Mendelian randomization study (2020) (0)
- GWAS of 9,260 Japanese individuals identified IL4R and the MHC region as associated loci of total serum IgE levels. (2021) (0)
- Construction of JRG (Japanese reference genome) with single-molecule real-time sequencing (2019) (0)
- Evaluation of reported pathogenic variants and their frequencies in a Japanese population based on a whole-genome reference panel of 2049 individuals (2017) (0)
- Relationship between age-related hearing loss and consumption of coffee and tea. (2023) (0)
- 1141526807 Expression of inducible microsomal prostaglandin E synthase in local endometriosis lesions (2006) (0)
- Metabolomic changes in the mouse retina after optic nerve injury (2018) (0)
- Isolation of recombinant cDNAs encoding chicken erythroid 6 aminolevulinate synthase ( antibody to 6-aminolevulinate synthase / red cell expression library ) (0)
- Cotranscription of genes for RNA polymerase subunits , 3 and I ' with genes for ribosomal proteins in Escherichia coli 1 ( transducing phages / gene cloning / rifampicin / RNA nucleotidyltransferase ) (0)
- Amino-acid selective isotope labeling enables simultaneous overlapping signal decomposition and information extraction from NMR spectra (2020) (0)
- 128. Detection of predictive makers for preeclampsia using NMR and GC–MS/MS metabolomics (2018) (0)
- Genomic landscape of chemical-induced lung tumors under Nrf2 different expression levels. (2022) (0)
- Corrigendum to "Protracted rosiglitazone treatment exacerbates inflammation in white adipose tissues of adipocyte-specific Nfe2l1 knockout mice" [Food Chem. Toxicol. 146 (2020) 111836]. (2022) (0)
- Novel candidates of pathogenic variants of the BRCA1 and BRCA2 genes in a 3,552 Japanese whole-genome sequence dataset (3.5KJPNv2) (2020) (0)
- Toxicity manifestations and sex differences due to MARTA olanzapine. (2023) (0)
- Author Correction: Characterizing rare and low-frequency height-associated variants in the Japanese population (2020) (0)
- Rose flavor compound β-damascone regulates dendritic cell-mediated immunoresponses by modulating the NRF2 pathway and ameliorates contact hypersensitivity (2022) (0)
- Cyclobutane Pyrimidine Dimers Produced with Narrowband UVB Are on Average More Mutagenic than Those with Broadband UVB in Mouse Skin (2021) (0)
- Development of long-read sequencing method for HLA-G region to elucidate the molecular mechanism of hypertensive disorders of pregnancy (2017) (0)
- Genome-wide identification of inter-individually variable DNA methylation sites improves the efficacy of epigenetic association studies (2017) (0)
- Genome-wide association study of the risk of chronic kidney disease and kidney-related traits in the Japanese population: J-Kidney-Biobank (2022) (0)
- Esterification Increases the Cell Permeability of Roxadustat, an Activator of Hypoxia-Inducible Factors, to Extend its Effective Duration (2021) (0)
- Blood lipids and the risk of colorectal cancer: Mendelian randomization analyses in the Japanese Consortium of Genetic Epidemiology studies. (2022) (0)
- Maternity-log Study : A Cohort Study towards Early Predictions of Pregnancy-related Diseases by Integrated Analysis of Healthcare and Multi-omics Data (2016) (0)
- Questionnaire Survey after Administration of Sedatives for Upper Gastrointestinal Endoscopy : With Respect to Pain Reduction (2008) (0)
- Association of Chronic Kidney Disease with Major Electrocardiographic Abnormalities and Radiographic Cardiomegaly in Japanese Male Workers (2012) (0)
- Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases (2020) (0)
- Genome-wide meta-analysis in Japanese populations identifies novel variants at the TMC6–TMC8 and SIX3–SIX2 loci associated with HbA1c (2017) (0)
- Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population (2019) (0)
- The return of individual genomic results to research participants: design and pilot study of Tohoku Medical Megabank Project (2021) (0)
- Biallelic GALM pathogenic variants cause a novel type of galactosemia (2018) (0)
- Design and Progress of Child Health Assessments at Community Support Centers in the Birth and Three-Generation Cohort Study of the Tohoku Medical Megabank Project. (2022) (0)
- Pathological variants in genes associated with disorders of sex development and central causes of hypogonadism in a whole-genome reference panel of 8380 Japanese individuals (2022) (0)
- Prevalence, Associated Factors, and Inter-Eye Differences of Refractive Errors in a Population-Based Japanese Cohort: The Tohoku Medical Megabank Eye Study. (2023) (0)
- Estimation of the carrier frequencies and proportions of potential patients by detecting causative gene variants associated with autosomal recessive bone dysplasia using a whole-genome reference panel of Japanese individuals (2021) (0)
- Identification of critical genetic variants associated with metabolic phenotypes of the Japanese population (2020) (0)
- Estimating carrier frequencies of newborn screening disorders using a whole-genome reference panel of 3552 Japanese individuals (2019) (0)
- Plasma metabolic disturbances during pregnancy and postpartum in women with depression (2022) (0)
- Correction: Biallelic GALM pathogenic variants cause a novel type of galactosemia (2020) (0)
- A training and education program for genome medical research coordinators in the genome cohort study of the Tohoku Medical Megabank Organization (2019) (0)
- Investigation of storage condition of blood sample by metabolome analysis (2017) (0)
- Multiomics and artificial intelligence enabled peripheral blood-based prediction of amnestic mild cognitive impairment. (2022) (0)
- Returning individual genomic results to population-based cohort study participants with BRCA1/2 pathogenic variants (2022) (0)
- Management of family relationship information for a three-generation cohort study (2019) (0)
- Investigating the association between glycaemic traits and colorectal cancer in the Japanese population using Mendelian randomisation (2023) (0)
- Aberrant activation of genes regulated by Maf recognition element (MARE) results in postnatal lethality in mouse (2017) (0)
- Correction to: Genome-wide association study identifies new loci for albuminuria in the Japanese population (2021) (0)
- Distributions of CHN compounds in meteorites record organic syntheses in the early solar system (2023) (0)
- Genotyping and statistical quality check of 18,000 participants in Tohoku Medical Megabank Cohort Study with Japonica-array V2. (2017) (0)
- CFH-CFHR1 hybrid genes in two cases of atypical hemolytic uremic syndrome (2023) (0)
- Genome-wide analysis of polymorphism × sodium interaction effect on blood pressure identifies a novel 3′-BCL11B gene desert locus (2018) (0)
- Japanese Multi Omics Reference Panel 2017 (jMorp2017) (2017) (0)
- ROLE OF NRF2 IN LUNG INJURY INDUCED BY DIESEL EXHAUST (2018) (0)
- Bidirectional Control of Transcription Factor GATA2 and Cyclin/Cdks in Hematopoietic Cells. (2008) (0)
- Regulation of mouse Gata1 gene expression in erythroid progenitors (2007) (0)
- Nrf2 regulation of glycogen metabolism in skeletal muscle (2015) (0)
- Enzymesand Lipid-Metabolizing Regulates the Cystine/Glutamate Transcription Factor Nrf1 Negatively (2014) (0)
- Nrf2-dependent Glutathione-regulated Transcriptional Program Controls Lung Type II Cell Proliferation and Protection against Oxidative Stress (2012) (0)
- that express GATA-1 at distinct levels Identification and characterization of 2 types of erythroid progenitors (2010) (0)
- Neonatal Hyperoxia Exposure Augments Respiratory Syncytial Virus Disease In Nrf2 Deficient Mice (2010) (0)
- assay information of the mouse qualitycontrol samples for HeliScopeCAGE (2017) (0)
- erythroid progenitors in transgenic reporter mice? -globin, GATA-1,or EpoR regulatory domains specifically mark β Do (2013) (0)
- Rescue of Erythropoietin-Deficient Mice From Anemia by Complementation with BAC Transgene. (2009) (0)
- Contents, Vol. 95, 1996 (1996) (0)
- UVA irradiation induces Nrf 2 activation in dermal fibroblasts : Protective role in UVA-induced apoptosis (2007) (0)
- Investigating The Role Of Nrf2 In Mesenchymal Stem Cell Survival And Function (2012) (0)
- Developmental regulation of Gata1 gene expression through adjacent GATA boxes and CP2-binding sites (2007) (0)
- Global Gene Expression Analysis in Developing Lungs from Nrf2 +/+ and Nrf2 -/- Neonates. (2009) (0)
- Supplementary Information for : Protein S-guanylation by the biological signal 8-nitroguanosine 3 ' , 5 '-cyclic monophosphate (2017) (0)
- G1HE-core contributes to the stage-specific expression of the Gata1 gene during erythroid development (2007) (0)
- [Pathophysiological regulation of cellular stress response by Keap1-Nrf2 system]. (2012) (0)
- Expression of 6-aminolevulinate synthase in avian cells: Separate genes encode erythroid-specific and nonspecific isozymes (erythrold-speciflc gene/heme biosynthesis) (2016) (0)
- Analyses of Heme-Regulated Genes during Erythoid Differentiation. (2007) (0)
- -aminolevulinate synthase (ALAS2)-deficient definitive erythroblasts δ Aberrant iron accumulation and oxidized status of erythroid-specific (2013) (0)
- Chapter 2 Leukemogenesis in Down syndrome (2017) (0)
- Two Distinct Transactivation Domains of GATA1 Contribute Megakaryopoiesis (2011) (0)
- The Direct Association of GATA-1 to Rb Is Necessary for Definitive Erythropoiesis. (2005) (0)
- Nrf2 Is Closely Related To Bleomycin Induced Airway Inflammation And Lung Fibrosis In Mice (2011) (0)
- [Identification of erythropoietin producing cells and erythropoietin gene regulation]. (2014) (0)
- Derepression of GATA factor-mediated repression releases erythropoietin in non-canonical erythropoietin producing cells (2015) (0)
- 4-hydroxynonenal induces nuclear translocation of the ubiquitin binding protein A170 in aortic smooth muscle cells (2002) (0)
- Translating molecular targets for chemoprevention into interventions for at-risk populations (2007) (0)
- P78. Nitric oxide-dependent sulfhydryl modification of Keap1 by 8-nitroguanosine 3′,5′-cyclic monophosphate (2008) (0)
- Functional analyses of Keap1 sensor cysteine residues by a novel mutational approach (2015) (0)
- Constitutive Expression of Aryl Hydrocarbon Receptor in Keratinocytes Causes Inflammatory Skin Lesions (2012) (0)
- Do beta-globin, GATA-1,or EpoR regulatory domains specifically mark erythroid progenitors in transgenic reporter mice? (2004) (0)
- Redox regulation in vascular endothelial and smooth muscle cells (2002) (0)
- 315 Air pollution activates Aryl hydrocarbon receptor of undifferentiated keratinocytes, leading to atopic dermatitis-like pathologies (2016) (0)
- Role of AhR in reproduction of female mice and expression of biological effects of endocrine disruptors (2004) (0)
- 125Stage-specific, gene-selective regulation of the embryonic and fetal β-type globin genes by the orphan nuclear receptors TR2 and TR4 (2007) (0)
- Transcription Factor Nrf2 in Myeloid-lineage Cells Protects Elastase-induced Emphysema (2017) (0)
- SUN-LB101 NRF2 Represses Obesity-Associated Adipose Tissue Inflammation in Mice (2020) (0)
- Crystal Structure of Keap1 in Complex with phosphorylated p62 (2013) (0)
- Induction of Hyperproliferative Fetal Megakaryopoiesis by An N-Terminally Truncated GATA1 Mutant. (2008) (0)
- Phenotypic Changes of Hematopoietic Stem Cells and Stromal Cells by Aberrant Expression of GATA−2; Possible Role for the Development of Aplastic Anemia. (2006) (0)
- GATA-2 partially rescued generation of hematopoietic cells from Jag 1 / AGM cells (2013) (0)
- Keap1-Nrf2 system for maintenance of redox homeostasis (2012) (0)
- Structural instability of IкB kinase β promotes autophagic degradation through enhancement of Keap1 binding (2018) (0)
- Transgene Insertion into the Proximity of the c-myb Gene Disrupts Erythroid-Megakaryocytic Lineage Bifurcation. (2006) (0)
- Specific Deletion of Keap1 in Endothelial Cells or/and Macrophages of SCD Mice Induces Nrf2 to Protect Tissues Against Oxidative Insults (2016) (0)
- Role of Nrf2/antioxidant response element in mammary carcinogenesis (2010) (0)
- Cover Picture: Eur. J. Immunol. 7/11 (2011) (0)
- Loss of the Gata1 Gene IE Exon Leads to Variant Transcript Expression and the Production of GATA1 Protein Lacking the N-Terminal Domain. (2009) (0)
- GATA Motifs Regulate Early Hematopoietic Lineage-Specific Expression of the Gata2 Gene (2005) (0)
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What Schools Are Affiliated With Masayuki Yamamoto?
Masayuki Yamamoto is affiliated with the following schools:
