Matthew C. Keller
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Matthew C. Kellerpsychology Degrees
Psychology
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Evolutionary Psychology
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Psychology
Matthew C. Keller's Degrees
- PhD Psychology University of California, Santa Barbara
- Masters Psychology University of California, Santa Barbara
- Bachelors Psychology University of California, Santa Barbara
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Why Is Matthew C. Keller Influential?
(Suggest an Edit or Addition)According to Wikipedia, Matthew C. Keller is an American behavioral and psychiatric geneticist. He is the Director of the Institute for Behavioral Genetics and a professor in the Department of Psychology and Neuroscience at the University of Colorado Boulder. He is known for his criticism of the candidate gene approach and for development of approaches in quantitative genetics.
Matthew C. Keller's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Biological Insights From 108 Schizophrenia-Associated Genetic Loci (2014) (6445)
- Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs (2013) (2011)
- Genome-wide association study identifies five new schizophrenia loci (2011) (1680)
- A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects: CNV Analysis Group and the Schizophrenia Working Group of the Psychiatric Genomics Consortium (2016) (1125)
- A critical review of the first 10 years of candidate gene-by-environment interaction research in psychiatry. (2011) (990)
- Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use (2018) (914)
- Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects (2016) (736)
- Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence (2018) (705)
- Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways (2015) (676)
- Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index (2015) (666)
- Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs (2012) (599)
- Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes (2017) (517)
- Gene × Environment Interaction Studies Have Not Properly Controlled for Potential Confounders: The Problem and the (Simple) Solution (2014) (514)
- Resolving the paradox of common, harmful, heritable mental disorders: which evolutionary genetic models work best? (2006) (465)
- Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function (2018) (417)
- Endophenotypes in the genetic analyses of mental disorders. (2006) (375)
- Mapping genomic loci implicates genes and synaptic biology in schizophrenia (2022) (361)
- No Support for Historical Candidate Gene or Candidate Gene-by-Interaction Hypotheses for Major Depression Across Multiple Large Samples. (2019) (345)
- Quantification of Inbreeding Due to Distant Ancestors and Its Detection Using Dense Single Nucleotide Polymorphism Data (2011) (338)
- Large-scale genomics unveils the genetic architecture of psychiatric disorders (2014) (321)
- Association of different adverse life events with distinct patterns of depressive symptoms. (2007) (298)
- Increased sensitivity in neuroimaging analyses using robust regression (2005) (294)
- A Warm Heart and a Clear Head (2005) (293)
- Detecting autozygosity through runs of homozygosity: A comparison of three autozygosity detection algorithms (2011) (264)
- Candidate Gene–Environment Interaction Research (2015) (234)
- Widespread Evidence for Non-Additive Genetic Variation in Cloninger’s and Eysenck’s Personality Dimensions using a Twin Plus Sibling Design (2005) (226)
- Meta-analysis of genome-wide association studies of anxiety disorders (2015) (220)
- Mental Exercising Through Simple Socializing: Social Interaction Promotes General Cognitive Functioning (2008) (218)
- Joint Analysis of Psychiatric Disorders Increases Accuracy of Risk Prediction for Schizophrenia, Bipolar Disorder, and Major Depressive Disorder (2015) (206)
- The evolutionary significance of depressive symptoms: different adverse situations lead to different depressive symptom patterns. (2006) (194)
- Meta-analysis of genome-wide association studies of anxiety disorders (2016) (190)
- Comparison of methods that use whole genome data to estimate the heritability and genetic architecture of complex traits (2017) (186)
- Molecular Genetic Evidence for Genetic Overlap between General Cognitive Ability and Risk for Schizophrenia: A Report from the Cognitive Genomics Consortium (COGENT) (2013) (184)
- GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium (2017) (178)
- MAINTENANCE OF GENETIC VARIATION IN HUMAN PERSONALITY: TESTING EVOLUTIONARY MODELS BY ESTIMATING HERITABILITY DUE TO COMMON CAUSAL VARIANTS AND INVESTIGATING THE EFFECT OF DISTANT INBREEDING (2012) (173)
- No Evidence That Schizophrenia Candidate Genes Are More Associated With Schizophrenia Than Noncandidate Genes (2017) (158)
- Is low mood an adaptation? Evidence for subtypes with symptoms that match precipitants. (2005) (157)
- Not by Twins Alone: Using the Extended Family Design to Investigate Genetic Influence on Political Beliefs (2010) (155)
- Are Extended Twin Family Designs Worth the Trouble? A Comparison of the Bias, Precision, and Accuracy of Parameters Estimated in Four Twin Family Models (2010) (151)
- Examining the role of common genetic variants on alcohol, tobacco, cannabis and illicit drug dependence: genetics of vulnerability to drug dependence. (2015) (145)
- Quantifying and Addressing Parameter Indeterminacy in the Classical Twin Design (2005) (128)
- The Trivers–Willard hypothesis of parental investment: No effect in the contemporary United States (2001) (121)
- Modeling Extended Twin Family Data I: Description of the Cascade Model (2009) (118)
- Runs of Homozygosity Implicate Autozygosity as a Schizophrenia Risk Factor (2012) (117)
- Genetic correlation between amyotrophic lateral sclerosis and schizophrenia (2017) (107)
- Complement genes contribute sex-biased vulnerability in diverse illnesses (2020) (92)
- Large-scale cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets (2017) (92)
- Estimating the Extent of Parameter Bias in the Classical Twin Design: A Comparison of Parameter Estimates From Extended Twin-Family and Classical Twin Designs (2005) (92)
- Genetic factors predisposing to homosexuality may increase mating success in heterosexuals (2008) (81)
- Imprint of assortative mating on the human genome (2018) (74)
- Additive genetic variation in schizophrenia risk is shared by populations of African and European descent. (2013) (74)
- The Genetic Correlation between Height and IQ: Shared Genes or Assortative Mating? (2013) (72)
- Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways (2019) (71)
- Genome-Wide Association Study of Behavioral Disinhibition in a Selected Adolescent Sample (2015) (62)
- A Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts (2020) (60)
- Recent methods for polygenic analysis of genome-wide data implicate an important effect of common variants on cardiovascular disease risk (2011) (59)
- Within-sibship genome-wide association analyses decrease bias in estimates of direct genetic effects (2022) (59)
- Within-sibship GWAS improve estimates of direct genetic effects (2021) (58)
- New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis. (2015) (58)
- Genetic influences on the human oral microbiome (2017) (50)
- Multivariate GWAS of psychiatric disorders and their cardinal symptoms reveal two dimensions of cross-cutting genetic liabilities (2019) (44)
- Genetic Factors That Increase Male Facial Masculinity Decrease Facial Attractiveness of Female Relatives (2014) (43)
- Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs (2012) (40)
- Type I Error Rates and Parameter Bias in Multivariate Behavioral Genetic Models (2019) (40)
- Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use (2019) (33)
- A polygenic resilience score moderates the genetic risk for schizophrenia (2019) (31)
- GWAS meta-analysis (N=279,930) identifies new genes and functional links to intelligence (2017) (31)
- Not by Twins Alone: Using the Extended Twin Family Designed to Investigate the Genetic Basis of Political Beliefs (2007) (30)
- Evolutionary Perspectives on Genetic and Environmental Risk Factors for Psychiatric Disorders. (2018) (30)
- Genome-wide autozygosity is associated with lower general cognitive ability (2016) (30)
- Estimation of Parental Effects Using Polygenic Scores (2020) (29)
- Estimating the Sex-Specific Effects of Genes on Facial Attractiveness and Sexual Dimorphism (2014) (28)
- The Association of Genotype-Based Inbreeding Coefficient with a Range of Physical and Psychological Human Traits (2014) (28)
- The Evolutionary Persistence of Genes That Increase Mental Disorders Risk (2008) (28)
- Independent evidence for an association between general cognitive ability and a genetic locus for educational attainment (2015) (27)
- Flexible Mx Specification of Various Extended Twin Kinship Designs (2009) (27)
- Assortative mating biases marker-based heritability estimators (2021) (26)
- Relationships between estimated autozygosity and complex traits in the UK Biobank (2018) (26)
- Facial averageness and genetic quality: Testing heritability, genetic correlation with attractiveness, and the paternal age effect. (2016) (26)
- Complement genes contribute sex-biased vulnerability in diverse disorders (2020) (25)
- Genetic variation links creativity to psychiatric disorders (2015) (23)
- Haplotypes of common SNPs can explain missing heritability of complex diseases (2015) (23)
- Modeling Extended Twin Family Data II: Power Associated With Different Family Structures (2009) (23)
- Commentary: Fundamental problems with candidate gene-by-environment interaction studies - reflections on Moore and Thoemmes (2016). (2017) (22)
- No Reliable Association between Runs of Homozygosity and Schizophrenia in a Well-Powered Replication Study (2016) (22)
- Twin studies to GWAS: there and back again (2021) (22)
- The Nature and Nurture of High IQ (2013) (22)
- Psychophysiological endophenotypes to characterize mechanisms of known schizophrenia genetic loci (2016) (22)
- Narrow-sense heritability estimation of complex traits using identity-by-descent information (2017) (22)
- Predicting Cognitive Executive Functioning with Polygenic Risk Scores for Psychiatric Disorders (2017) (21)
- Shared additive genetic influences on DSM-IV criteria for alcohol dependence in subjects of European ancestry. (2015) (20)
- A recessive genetic model and runs of homozygosity in major depressive disorder (2014) (20)
- Evolutionary behavioral genetics (2015) (19)
- NO RELATIONSHIP BETWEEN INTELLIGENCE AND FACIAL ATTRACTIVENESS IN A LARGE, GENETICALLY INFORMATIVE SAMPLE. (2015) (18)
- Shared additive genetic variation for alcohol dependence among subjects of African and European ancestry (2019) (18)
- Genetic diversity fuels gene discovery for tobacco and alcohol use (2022) (18)
- Subtle stratification confounds estimates of heritability from rare variants (2016) (18)
- Erratum: GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium (2017) (17)
- Corrigendum: GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function (2017) (17)
- Phenotypic covariance across the entire spectrum of relatedness for 86 billion pairs of individuals (2021) (16)
- Model-based assessment of replicability for genome-wide association meta-analysis (2021) (15)
- Non‐pathological paternal isodisomy of chromosome 2 detected from a genome‐wide SNP scan (2009) (15)
- A fast and accurate method for detection of IBD shared haplotypes in genome-wide SNP data (2016) (15)
- Running head: DETECTING ANCIENT INBREEDING Quantification of inbreeding due to distant ancestors and its detection using dense SNP data (2011) (14)
- Genome-Wide Association Study of Over 427,000 Individuals Establishes Executive Functioning as a Neurocognitive Basis of Psychiatric Disorders Influenced by GABAergic Processes (2019) (13)
- GWAS of Over 427,000 Individuals Establishes GABAergic and Synaptic Molecular Pathways as Key for Cognitive Executive Functions (2019) (13)
- Imputation of behavioral candidate gene repeat variants in 486,551 publicly-available UK Biobank individuals (2019) (13)
- Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360) (2017) (12)
- Being Unpredictable (2010) (12)
- The Role of Mutations in Human Mating 1 Running head: THE ROLE OF MUTATIONS IN HUMAN MATING The Role of Mutations in Human Mating (2006) (11)
- GeneEvolve: a fast and memory efficient forward-time simulator of realistic whole-genome sequence and SNP data (2017) (11)
- Which evolutionary genetic models best explain the persistence of common, harmful, heritable mental disorders (2006) (10)
- A test of the facultative calibration/reactive heritability model of extraversion. (2015) (10)
- Using partitioned heritability methods to explore genetic architecture (2018) (9)
- Bias and Precision of Parameter Estimates from Models Using Polygenic Scores to Estimate Environmental and Genetic Parental Influences (2020) (9)
- An evolutionary framework for mental disorders: Integrating adaptationist and evolutionary genetic models (2006) (9)
- Theory and Methods in Evolutionary Behavioral Genetics (2010) (8)
- Linkage disequilibrium between single nucleotide polymorphisms and hypermutable loci (2015) (8)
- No Evidence for Social Genetic Effects or Genetic Similarity Among Friends Beyond that Due to Population Stratification: A Reappraisal of Domingue et al (2018) (2019) (8)
- Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function (2019) (7)
- The role of a priori-identified addiction and smoking gene sets in smoking behaviors (2019) (5)
- The etiology of DSM-5 alcohol use disorder: Evidence of shared and non-shared additive genetic effects. (2019) (5)
- Assessing the accuracy of perceptions of intelligence based on heritable facial features (2017) (5)
- Testing the moderation of quantitative gene by environment interactions in unrelated individuals (2017) (5)
- Genome-wide Association Study Shows That Executive Functioning Is Influenced by GABAergic Processes and Is a Neurocognitive Genetic Correlate of Psychiatric Disorders (2022) (5)
- Problems with the imprinting hypothesis of schizophrenia and autism (2008) (5)
- Genomic partitioning of inbreeding depression in humans. (2021) (5)
- Mutational load analysis of unrelated individuals (2011) (5)
- Facial Trustworthiness is Associated with Heritable Aspects of Face Shape (2017) (5)
- Evidence of Shared Genome-Wide Additive Genetic Effects on Interpersonal Trauma Exposure and Generalized Vulnerability to Drug Dependence in a Population of Substance Users. (2016) (5)
- Identifying nootropic drug targets via large-scale cognitive GWAS and transcriptomics (2020) (4)
- Genetic architecture of four smoking behaviors using partitioned SNP heritability. (2021) (4)
- Rare genetic variants explain missing heritability in smoking (2022) (4)
- M41 IDENTIFYING NOOTROPIC DRUG TARGETS VIA LARGE-SCALE COGNITIVE GWAS AND TRANSCRIPTOMICS (2019) (4)
- Identification and characterization of genetic risk shared across 24 chronic pain conditions in the UK Biobank. (2022) (4)
- Evolutionary theories of schizophrenia must ultimately explain the genes that predispose to it (2004) (4)
- Multi-Trait Analysis of GWAS and Biological Insights Into Cognition: A Response to Hill (2018) (2018) (3)
- Whole-Genome Pathway Analysis on 132,497 Individuals Identifies Novel Gene-Sets Associated with Body Mass Index (2014) (3)
- A comprehensive meta-analysis of human assortative mating in 22 complex traits 2 3 (2022) (3)
- A Warm Heart and a Clear Head: The Effects of Weather on Human Mood and Cognition (2016) (3)
- Genetic architecture of four smoking behaviors using partitioned h2SNP. (2020) (3)
- Data Related to Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use (2019) (3)
- Predicting causal genes from psychiatric genome-wide association studies using high-level etiological knowledge (2022) (2)
- Additive genetic variation in risk to schizophrenia across African American and European American populations (2012) (2)
- Gene expression imputation across multiple brain regions provides insights into schizophrenia risk (2019) (2)
- No Evidence for Social Genetic Effects or Genetic Similarity Among Friends Beyond that Due to Population Stratification: A Reappraisal of Domingue et al (2018) (2019) (2)
- The social prediction dynamic: A legacy of cognition and mixed motives (2011) (2)
- Narrow-sense heritability estimation of complex traits using identity-by-descent information (2018) (2)
- Novel approach for parallelizing pairwise comparison problems as applied to detecting segments identical by decent in whole-genome data (2020) (2)
- Declining autozygosity over time: an exploration in over 1 million individuals from three diverse cohorts (2022) (2)
- Exploring the relationships between autozygosity, educational attainment, and cognitive ability in a contemporary, trans-ancestral American sample (2021) (1)
- Genetic influences on the human oral microbiome (2017) (1)
- 15 EFFECTS OF ASSORTATIVE MATING ON ESTIMATES OF SNP HERITABILITY (2019) (1)
- Author Correction: Assortative mating biases marker-based heritability estimators (2022) (1)
- Genetic architecture of smoking: Evaluating rare variant contribution from deep whole-genome sequencing of up to 26,000 individuals (2021) (1)
- haplotypes in genome-wide SNP data " & ! " ' ! " ( ! (2016) (1)
- The estimation of environmental and genetic parental influences (2022) (1)
- Measurement Error Cannot Account for Failed Replications of Historic Candidate Gene-by-Environment Hypotheses: Response to Vrshek-Schallhorn et al. (2019) (1)
- Imputation of Behavioral Candidate Gene Repeat Polymorphisms in 486,551 Publicly-Available UK Biobank Individuals (2018) (1)
- An Evolutionary Genetic Framework for Heritable Disorders (2008) (1)
- Functioning Mental Exercising Through Simple Socializing : Social Interaction Promotes General Cognitive (2008) (1)
- Correction: The Genetic Correlation between Height and IQ: Shared Genes or Assortative Mating? (2014) (1)
- Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function (2019) (0)
- Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence (2018) (0)
- Full title: No evidence that schizophrenia candidate genes are more associated with schizophrenia than non-candidate genes (2017) (0)
- Assortative mating biases marker-based heritability estimators (2022) (0)
- 30ENVIRONMENTAL FACTORS ARE OFTEN HERITABLE: DOES THIS BIAS POLYGENIC GENE-BY-ENVIRONMENT INTERACTION ANALYSES? (2019) (0)
- Mechanisms of Psychiatric Illness (0)
- Investigating heterogeneous genetic effects contributing to smoking behaviors (2021) (0)
- Comparison of methods that use whole genome data to estimate the heritability and genetic architecture of complex traits (2018) (0)
- Correction: Maintenance of variation in human personality: testing evolutionary models by estimating heritability due to common causal variants and investigating the effect of distant inbreeding (vol 66, pg 3238, 2012) (2013) (0)
- Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function (2018) (0)
- Genome-Wide Association Study of Behavioral Disinhibition in a Selected Adolescent Sample (2015) (0)
- Age at first birth in women is genetically associated with increased risk of schizophrenia (2018) (0)
- Facial Trustworthiness is Associated with Heritable Aspects of Face Shape (2017) (0)
- GWAS meta-analysis (N=279,930) identifies new genes and functional links to general cognitive ability (2018) (0)
- Disentangling the influences of parental genetics on offspring's cognition, education, and psychopathology via genetic and phenotypic pathways. (2022) (0)
- Potential bias in genetic correlations (2022) (0)
- VKučinskas-2001-2016 (2016) (0)
- SA49 A QUANTITATIVE ANALYSIS OF DISCREPANCIES BETWEEN CANDIDATE GENE AND GENOME-WIDE STUDIES OF COMPLEX TRAITS AND RELATED ENDOPHENOTYPES (2019) (0)
- Publisher Correction: Gene expression imputation across multiple brain regions provides insights into schizophrenia risk (2019) (0)
- 25EXPLORING THE GENETIC ARCHITECTURE OF PSYCHIATRIC DISORDERS USING PARTITIONED HERITABILITY APPROACHES (2019) (0)
- NAME OF PRESENTING AUTHOR: Jared V. Balbona EMAIL ADDRESS OF PRESENTING AUTHOR: jaba5258@colorado.edu LOCATION OF PRESENTING AUTHOR: America (North) TIME ZONE OF PRESENTING AUTHOR: Mountain Daylight Time (Colorado) TYPE OF SUBMISSION: Oral paper (2020) (0)
- Correlations between human mating partners: a comprehensive meta-analysis of 22 traits and raw data analysis of 133 traits in the UK Biobank (2023) (0)
- An evolutionary investigation of depressed mood: The relationship between daily stressors and patterns of depressive symptoms. (2022) (0)
- Imprint of assortative mating on the human genome (2018) (0)
- Estimating the Sex-Specific Effects of Genes on Facial Attractiveness and Sexual Dimorphism (2013) (0)
- Nick Martin as a Mentor — A Perspective (2020) (0)
- Running Title: Find IBD Shared Haplotypes Rapidly (2016) (0)
- Predicting Cognitive Executive Functioning with Polygenic Risk Scores for Psychiatric Disorders (2016) (0)
- Imputation of behavioral candidate gene repeat variants in 486,551 publicly-available UK Biobank individuals (2019) (0)
- Genetic analysis of male and female twins does not support 'indirect benefits' account of masculine male face shape (2013) (0)
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