Matthew D. Breyer
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Matthew D. Breyer's Degrees
- PhD Biomedical Sciences Johns Hopkins University
- Doctorate Medicine Harvard University
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(Suggest an Edit or Addition)Matthew D. Breyer's Published Works
Published Works
- Prostanoid receptors: subtypes and signaling. (2001) (1016)
- Cyclooxygenase-2 is associated with the macula densa of rat kidney and increases with salt restriction. (1994) (903)
- Mouse models of diabetic nephropathy. (2009) (853)
- Thiazolidinediones expand body fluid volume through PPARγ stimulation of ENaC-mediated renal salt absorption (2005) (607)
- Mesangial cell, glomerular and renal vascular responses to endothelin in the rat kidney. Elucidation of signal transduction pathways. (1989) (424)
- Salt–sensitive hypertension and reduced fertility in mice lacking the prostaglandin EP2 receptor (1999) (398)
- Serial determination of glomerular filtration rate in conscious mice using FITC-inulin clearance. (2004) (323)
- Endothelial nitric oxide synthase deficiency produces accelerated nephropathy in diabetic mice. (2006) (322)
- Physiological regulation of cyclooxygenase-2 in the kidney. (2001) (296)
- Peroxisome proliferator-activated receptors (PPARs): novel therapeutic targets in renal disease. (2001) (292)
- Prostaglandin E receptors and the kidney. (2000) (291)
- Opposite effects of cyclooxygenase-1 and -2 activity on the pressor response to angiotensin II. (2002) (275)
- Sirt1 activation protects the mouse renal medulla from oxidative injury. (2010) (274)
- Characterization of susceptibility of inbred mouse strains to diabetic nephropathy. (2005) (273)
- Alterations in the regulation of androgen-sensitive Cyp 4a monooxygenases cause hypertension (2001) (247)
- Physiological regulation of prostaglandins in the kidney. (2008) (241)
- G protein-coupled prostanoid receptors and the kidney. (2001) (231)
- Failure of ductus arteriosus closure and remodeling in neonatal mice deficient in cyclooxygenase-1 and cyclooxygenase-2. (2001) (222)
- Cyclooxygenase-2-selective inhibitors impair glomerulogenesis and renal cortical development. (2000) (202)
- Long-term treatment of glucagon-like peptide-1 analog exendin-4 ameliorates diabetic nephropathy through improving metabolic anomalies in db/db mice. (2007) (196)
- Conditional Knockout of Macrophage PPARγ Increases Atherosclerosis in C57BL/6 and Low-Density Lipoprotein Receptor–Deficient Mice (2005) (190)
- Utility of endogenous creatinine clearance as a measure of renal function in mice. (2004) (184)
- PKHD1 protein encoded by the gene for autosomal recessive polycystic kidney disease associates with basal bodies and primary cilia in renal epithelial cells. (2004) (178)
- Deficiency of endothelial nitric-oxide synthase confers susceptibility to diabetic nephropathy in nephropathy-resistant inbred mice. (2007) (175)
- The next generation of therapeutics for chronic kidney disease (2016) (175)
- Expression of peroxisome proliferator-activated receptors in urinary tract of rabbits and humans. (1997) (174)
- Expression of Peroxisome Proferator-Activated Receptor γ (PPARγ) in Human Transitional Bladder Cancer and its Role in Inducing Cell Death (1999) (170)
- PPARα agonist fenofibrate improves diabetic nephropathy in db/db mice. Commentary (2006) (168)
- Reduction of renal superoxide dismutase in progressive diabetic nephropathy. (2009) (161)
- Cloning, expression, and regulation of rabbit cyclooxygenase-2 in renal medullary interstitial cells. (1997) (161)
- Functional and molecular aspects of renal prostaglandin receptors. (1996) (154)
- Enhanced expression of cyclooxygenase-2 in high grade human transitional cell bladder carcinomas. (2000) (150)
- Key enzymes for renal prostaglandin synthesis: site-specific expression in rodent kidney (rat, mouse). (2003) (147)
- Dehydration activates an NF-kappaB-driven, COX2-dependent survival mechanism in renal medullary interstitial cells. (2000) (147)
- Luminal NaCl delivery regulates basolateral PGE2 release from macula densa cells. (2003) (143)
- Physiologic and pathophysiologic roles of lipid mediators in the kidney. (2007) (143)
- Salt-sensitive hypertension is associated with dysfunctional Cyp4a10 gene and kidney epithelial sodium channel. (2006) (142)
- Prostaglandin E2 inhibits renal collecting duct Na+ absorption by activating the EP1 receptor. (1998) (138)
- Circulating αKlotho influences phosphate handling by controlling FGF23 production. (2012) (138)
- Cyclooxygenase 2 and the kidney (2001) (133)
- Accelerated diabetic nephropathy in mice lacking the peroxisome proliferator-activated receptor alpha. (2006) (133)
- Prostaglandin E2-EP4 Receptor Promotes Endothelial Cell Migration via ERK Activation and Angiogenesis in Vivo* (2007) (129)
- Hormonal signaling and regulation of salt and water transport in the collecting duct. (1994) (128)
- Prostaglandin E2 inhibits sodium transport in rabbit cortical collecting duct by increasing intracellular calcium. (1991) (127)
- PGE2 inhibits AVP-induced water flow in cortical collecting ducts by protein kinase C activation. (1990) (125)
- Lithium treatment inhibits renal GSK-3 activity and promotes cyclooxygenase 2-dependent polyuria. (2005) (123)
- Evidence that separate PGE2 receptors modulate water and sodium transport in rabbit cortical collecting duct. (1993) (123)
- Differential expression of the intermediate filament protein nestin during renal development and its localization in adult podocytes. (2006) (118)
- Alterations in lipoxygenase and cyclooxygenase-2 catalytic activity and mRNA expression in prostate carcinoma. (2001) (116)
- Upregulation of type I collagen by TGF-β in mesangial cells is blocked by PPARγ activation (2002) (110)
- Differential localization of prostaglandin E receptor subtypes in human kidney. (1996) (107)
- Mouse models of diabetic nephropathy. (2005) (107)
- Peroxisome Proliferator-activated Receptor δ Activation Promotes Cell Survival following Hypertonic Stress* (2002) (105)
- Prostaglandin receptors: their role in regulating renal function. (2000) (104)
- Antihypertensive effects of selective prostaglandin E2 receptor subtype 1 targeting. (2007) (104)
- Regulation of renal function by prostaglandin E receptors. (1998) (103)
- Selective targeting of cyclooxygenase-2 reveals its role in renal medullary interstitial cell survival. (1999) (100)
- Macrophage EP4 deficiency increases apoptosis and suppresses early atherosclerosis. (2008) (96)
- Molecular Cloning, Enzymatic Characterization, Developmental Expression, and Cellular Localization of a Mouse Cytochrome P450 Highly Expressed in Kidney* (1999) (96)
- Prostaglandin E2-Mediated Attenuation of Mesocortical Dopaminergic Pathway Is Critical for Susceptibility to Repeated Social Defeat Stress in Mice (2012) (96)
- Hypertonic Stress Activates Glycogen Synthase Kinase 3β-mediated Apoptosis of Renal Medullary Interstitial Cells, Suppressing an NFκB-driven Cyclooxygenase-2-dependent Survival Pathway* (2003) (93)
- Alternative splicing generates multiple isoforms of a rabbit prostaglandin E2 receptor. (1994) (93)
- Cyclooxygenase-2 expression is associated with the renal macula densa of patients with Bartter-like syndrome. (2000) (92)
- PPARalpha agonist fenofibrate improves diabetic nephropathy in db/db mice. (2006) (91)
- Characterization of murine vasopressor and vasodepressor prostaglandin E(2) receptors. (2000) (91)
- Membrane-associated PGE synthase-1 (mPGES-1) is coexpressed with both COX-1 and COX-2 in the kidney. (2004) (87)
- Differentiation of Cyclooxygenase 1- and 2–Derived Prostanoids in Mouse Kidney and Aorta (2006) (87)
- Cytochrome P450 CYP2J9, a New Mouse Arachidonic Acid ω-1 Hydroxylase Predominantly Expressed in Brain* (2001) (86)
- Generation of a conditional allele of the mouse prostaglandin EP4 receptor (2004) (84)
- Expression of peroxisome proliferator-activated receptor gamma (PPARgamma) in human transitional bladder cancer and its role in inducing cell death. (1999) (82)
- In situ hybridization and localization of mRNA for the rabbit prostaglandin EP3 receptor. (1993) (81)
- Urogenital distribution of a mouse membrane-associated prostaglandin E(2) synthase. (2001) (78)
- Segmental distribution of epidermal growth factor binding sites in rabbit nephron. (1990) (78)
- Expression of peroxisome proliferator-activated receptors in urinary tract of rabbits and humans. (1997) (77)
- Overexpression of cyclooxygenase-2 predisposes to podocyte injury. (2007) (76)
- Luminal prostaglandin E receptors regulate salt and water transport in rabbit cortical collecting duct. (1995) (76)
- Markers of early progressive renal decline in type 2 diabetes suggest different implications for etiological studies and prognostic tests development. (2018) (75)
- 5,6-EET inhibits ion transport in collecting duct by stimulating endogenous prostaglandin synthesis. (1995) (71)
- Epidermal growth factor inhibits the hydroosmotic effect of vasopressin in the isolated perfused rabbit cortical collecting tubule. (1988) (69)
- COX2 Activity Promotes Organic Osmolyte Accumulation and Adaptation of Renal Medullary Interstitial Cells to Hypertonic Stress* (2003) (68)
- Update on cyclooxygenase-2 inhibitors. (2006) (68)
- Cloning and expression of the rabbit prostaglandin EP4 receptor. (1996) (67)
- Peroxisome proliferator-activated receptor-γ activity is associated with renal microvasculature (2001) (66)
- Expression and Molecular Pharmacology of the Mouse CRTH2 Receptor (2003) (66)
- The Role of PPARs in the Transcriptional Control of Cellular Processes. (2002) (65)
- Glycogen synthase kinase 3 inhibition improves insulin-stimulated glucose metabolism but not hypertension in high-fat-fed C57BL/6J mice (2007) (64)
- A prospective study of multiple protein biomarkers to predict progression in diabetic chronic kidney disease. (2014) (64)
- Peroxisome Proliferator–Activated Receptor α/γ Dual Agonist Tesaglitazar Attenuates Diabetic Nephropathy in db/db Mice (2007) (63)
- Cytochrome P450 metabolites of arachidonic acid are potent inhibitors of vasopressin action on rabbit cortical collecting duct. (1989) (61)
- A maladaptive role for EP4 receptors in podocytes. (2010) (60)
- Markers of glycemic control in the mouse: comparisons of 6-h- and overnight-fasted blood glucoses to Hb A1c. (2008) (58)
- Diabetic nephropathy: of mice and men. (2005) (58)
- Upregulation of type I collagen by TGF-beta in mesangial cells is blocked by PPARgamma activation. (2002) (57)
- Phorbol myristate acetate, dioctanoylglycerol, and phosphatidic acid inhibit the hydroosmotic effect of vasopressin on rabbit cortical collecting tubule. (1987) (56)
- Cellular mechanisms of prostaglandin E2 and vasopressin interactions in the collecting duct. (1990) (55)
- Endothelin-1 receptor antagonist: effects on endothelin- and cyclosporine-treated mesangial cells. (1992) (54)
- Liver X receptor-α mediates cholesterol efflux in glomerular mesangial cells (2004) (54)
- Liver X receptor agonist TO-901317 upregulates SCD1 expression in renal proximal straight tubule. (2006) (53)
- Contribution of prostaglandin EP(2) receptors to renal microvascular reactivity in mice. (2002) (52)
- Axial heterogeneity of vasopressin-receptor subtypes along the human and mouse collecting duct. (2007) (52)
- Prostaglandin-dependent modulation of dopaminergic neurotransmission elicits inflammation-induced aversion in mice. (2016) (51)
- Differential, inducible gene targeting in renal epithelia, vascular endothelium, and viscera of Mx1Cre mice. (2003) (50)
- Inactivation of the E-Prostanoid 3 Receptor Attenuates the Angiotensin II Pressor Response via Decreasing Arterial Contractility (2012) (48)
- Glomerular injury is exacerbated in diabetic integrin α1-null mice (2006) (48)
- Apoptosis of the thick ascending limb results in acute kidney injury. (2008) (45)
- Single amino acid substitution in aquaporin 11 causes renal failure. (2008) (45)
- Expression of the prostaglandin F receptor (FP) gene along the mouse genitourinary tract. (2003) (44)
- Better nephrology for mice--and man. (2010) (44)
- Roles of lipid mediators in kidney injury. (2007) (43)
- Developing Treatments for Chronic Kidney Disease in the 21st Century. (2016) (42)
- Role of cytochrome P-450 epoxygenase metabolites in EGF signaling in renal proximal tubule. (1995) (42)
- Anti sense DNA down-regulates proteins kinase C-epsilon and enhances vasopressin-stimulated Na+ absorption in rabbit cortical collecting duct. (1995) (42)
- Structure‐Function Analyses of Eicosanoid Receptors: Physiologic and Therapeutic Implications (2000) (42)
- Urine concentrating defect in prostaglandin EP1-deficient mice. (2007) (41)
- Regulation of rabbit medullary collecting duct cell pH by basolateral Na+/H+ and Cl-/base exchange. (1989) (40)
- Cyclooxygenase-2 selective inhibitors and the kidney. (2001) (40)
- Feedback inhibition of cyclic adenosine monophosphate-stimulated Na+ transport in the rabbit cortical collecting duct via Na(+)-dependent basolateral Ca++ entry. (1991) (40)
- EP1−/− Mice Have Enhanced Osteoblast Differentiation and Accelerated Fracture Repair (2010) (39)
- Volume and agonist-induced regulation of myosin light-chain phosphorylation in glomerular mesangial cells. (1993) (38)
- Effects of trifluoperazine, ouabain, and ethacrynic acid on intestinal calcium transport. (1983) (38)
- PGE2 regulates cAMP production in cultured rabbit CCD cells: evidence for dual inhibitory mechanisms. (1992) (38)
- Regulation of water and salt transport in collecting duct through calcium-dependent signaling mechanisms. (1991) (38)
- Cyclooxygenase-1 Deficiency in Bone Marrow Cells Increases Early Atherosclerosis in Apolipoprotein E– and Low-Density Lipoprotein Receptor–Null Mice (2005) (37)
- Cyclooxygenase-2–Dependent Prostacyclin Formation Is Regulated by Low Density Lipoprotein Cholesterol In Vitro (2002) (37)
- Improved clinical trial enrollment criterion to identify patients with diabetes at risk of end-stage renal disease. (2017) (36)
- Peroxisome proliferator activated receptor alpha/gamma dual agonist tesaglitazar attenuates diabetic nephropathy in db/db mice. (2007) (35)
- Peroxisome proliferator-activated receptor-gamma activity is associated with renal microvasculature. (2001) (34)
- Expression of nestin in the podocytes of normal and diseased human kidneys. (2007) (33)
- cAMP-dependent protein kinase mediates hydrosmotic effect of vasopressin in collecting duct. (1992) (33)
- Glomerular injury is exacerbated in diabetic integrin alpha1-null mice. (2006) (33)
- Mineralocorticoid regulation of cyclooxygenase-2 expression in rat renal medulla. (2002) (32)
- Aberrant bispecific antibody pharmacokinetics linked to liver sinusoidal endothelium clearance mechanism in cynomolgus monkeys (2016) (32)
- Characterization of a Rabbit Kidney Prostaglandin F2α Receptor Exhibiting Gi-restricted Signaling That Inhibits Water Absorption in the Collecting Duct* (2005) (31)
- Functional characterization of alpha- and beta-intercalated cell types in rabbit cortical collecting duct. (1991) (30)
- SOD1, but not SOD3, deficiency accelerates diabetic renal injury in C57BL/6-Ins2(Akita) diabetic mice. (2012) (30)
- Generation and functional confirmation of a conditional null PPARγ allele in mice (2002) (30)
- Epithelial COX-2 Expression Is Not Regulated By Nitric Oxide in Rodent Renal Cortex (2002) (29)
- Liver X receptor-alpha mediates cholesterol efflux in glomerular mesangial cells. (2004) (29)
- Effect of selective cyclooxygenase-2 (COX-2) inhibitor treatment on glucose-stimulated insulin secretion in C57BL/6 mice. (2007) (29)
- Importance of the extracellular domain for prostaglandin EP(2) receptor function. (1999) (29)
- Overcoming Barriers in Kidney Health-Forging a Platform for Innovation. (2016) (27)
- Phorbol ester and A23187 have additive but mechanistically separate effects on vasopressin action in rabbit collecting tubule. (1988) (27)
- Defective expression of Tamm-Horsfall protein/uromodulin in COX-2-deficient mice increases their susceptibility to urinary tract infections. (2005) (27)
- Prostaglandin E-prostanoid-3 receptor activation of cyclic AMP response element-mediated gene transcription. (1999) (27)
- Functional and molecular aspects of prostaglandin E receptors in the cortical collecting duct. (1995) (27)
- Regulation of net bicarbonate transport in rabbit cortical collecting tubule by peritubular pH, carbon dioxide tension, and bicarbonate concentration. (1986) (26)
- Cloning and expression of the rabbit prostaglandin EP2 receptor (2002) (26)
- Expression of mouse membrane-associated prostaglandin E2 synthase-2 (mPGES-2) along the urogenital tract. (2006) (26)
- Mouse EP3 α, β, and γ Receptor Variants Reduce Tumor Cell Proliferation and Tumorigenesis in Vivo* (2008) (26)
- Molecular cloning and characterization of mouse CYP2J6, an unstable cytochrome P450 isoform. (2002) (25)
- Measurement of glomerular filtration rate in conscious mice. (2009) (25)
- Mapping the single-cell transcriptomic response of murine diabetic kidney disease to therapies. (2022) (25)
- Targeting VE-PTP phosphatase protects the kidney from diabetic injury (2019) (25)
- Dose-dependent heterogenous actions of vasopressin in rabbit cortical collecting ducts. (1989) (24)
- Diphtheria Immunity in Massachusetts—A Study of Three Urban Patient Populations (1984) (24)
- Cardiovascular effects of selective COX-2 inhibition: is there a class effect? The International COX-2 Study Group. (2006) (23)
- Prostaglandin E 2 inhibits renal collecting duct Na + absorption by activating the EP 1 receptor (1998) (22)
- A sensitized screen of N-ethyl-N-nitrosourea-mutagenized mice identifies dominant mutants predisposed to diabetic nephropathy. (2007) (21)
- Increased severity of renal impairment in nephritic mice lacking the EP1 receptor. (2006) (21)
- Cytosolic acidification stimulates a calcium influx that activates Na(+)-H+ exchange in LLC-PK1. (1991) (21)
- Generation of a Tenascin-C-CreER2 Knockin Mouse Line for Conditional DNA Recombination in Renal Medullary Interstitial Cells (2013) (20)
- Enhanced pressor response to acute Ang II infusion in mice lacking membrane-associated prostaglandin E2 synthase-1 (2010) (19)
- Peroxisome Proliferator-Activated Receptor-Alpha Deficiency Protects Aged Mice from Insulin Resistance Induced by High-Fat Diet (2007) (19)
- Effects of global or targeted deletion of the EP4 receptor on the response of osteoblasts to prostaglandin in vitro and on bone histomorphometry in aged mice. (2009) (18)
- Hypertension and cyclooxygenase-2 inhibitors: target: the renal medulla. (2004) (18)
- Increased dietary sodium induces COX2 expression by activating NFκB in renal medullary interstitial cells (2014) (17)
- Genomic structure and genitourinary expression of mouse cytosolic prostaglandin E2 synthase gene (2003) (17)
- Progressive Renal Disease Established by Renin-Coding Adeno-Associated Virus-Driven Hypertension in Diverse Diabetic Models. (2017) (17)
- Role of TGF-alpha in the progression of diabetic kidney disease. (2017) (17)
- Meningorectal fistula as a cause of polymicrobial anaerobic meningitis. (1982) (16)
- Muscarinic receptor activation inhibits AVP-induced water flow in rabbit cortical collecting ducts. (1991) (15)
- COX2 selective NSAIDs and renal function: gain without pain? (1999) (15)
- Inflammatory modulation and wound repair. (2003) (15)
- ATP-inhibitable Cl- channel in apical membranes of cultured rabbit cortical collecting duct cells. (1993) (14)
- Effect of deletion of the prostaglandin EP4 receptor on stimulation of calcium release from cultured mouse calvariae: impaired responsiveness in heterozygotes. (2005) (14)
- Estimated glomerular filtration rate progression in UK primary care patients with type 2 diabetes and diabetic kidney disease: a retrospective cohort study (2015) (13)
- Prostaglandin Receptors in the Kidney: A New Route for Intervention? (1998) (13)
- Cyclooxygenase-2 selective inhibitors and the kidney (2001) (13)
- ANIMAL MODELS OF DIABETIC COMPLICATIONS CONSORTIUM (U01 DK61018) (2004) (13)
- Novel avenues for drug discovery in diabetic kidney disease (2018) (13)
- Bradykinin B2 type receptor activation regulates fluid and electrolyte transport in the rabbit kidney (2005) (12)
- Expression of Mediators of Renal Injury in the Remnant Kidney of ROP Mice Is Attenuated by Cyclooxygenase-2 Inhibition (2005) (12)
- Profibrotic Circulating Proteins and Risk of Early Progressive Renal Decline in Patients With Type 2 Diabetes With and Without Albuminuria (2020) (12)
- Diabetic nephropathy: leveraging mouse genetics (2006) (12)
- Generation and Activity of a Humanized Monoclonal Antibody That Selectively Neutralizes the Epidermal Growth Factor Receptor Ligands Transforming Growth Factor-α and Epiregulin (2014) (12)
- Drug discovery for diabetic nephropathy: trying the leap from mouse to man. (2012) (11)
- Triple signal transduction model for the mechanism of PGE2 actions in rabbit cortical collecting duct. (1991) (11)
- Mechanisms and regulation of renal H+ and HCO3- transport. (1987) (11)
- Stacking the deck for drug discovery in diabetic nephropathy: in search of an animal model. (2008) (11)
- A Novel Aldosterone Antagonist Limits Renal Injury in 5/6 Nephrectomy (2017) (11)
- Improving productivity of modern-day drug discovery (2014) (11)
- From bench to patient: model systems in drug discovery (2015) (10)
- Viral transduction of renin rapidly establishes persistent hypertension in diverse murine strains. (2015) (10)
- Arachidonic Acid Metabolites and the Kidney (2011) (10)
- Targeted gene disruption of the prostaglandin E2 EP2 receptor. (2002) (9)
- Diabetic nephropathy: a national dialogue. (2013) (9)
- Characterization of diabetic nephropathy in a transgenic model of hypoinsulinemic diabetes. (2006) (8)
- Induction of rabbit cyclooxygenase 2 in the anterior uvea following glaucoma filtration surgery. (1997) (8)
- Insight into the genetics of diabetic nephropathy through the study of mice (2008) (8)
- Nonselective Cyclooxygenase Inhibition Retards Cyst Progression in a Murine Model of Autosomal Dominant Polycystic Kidney Disease (2019) (8)
- Phosphatidates inhibit vasopressin-induced water transport via protein kinase C activation. (1989) (7)
- Genetics of diabetic nephropathy: lessons from mice. (2007) (7)
- Generation of a conditional allele for the mouse endothelial nitric oxide synthase gene (2012) (7)
- Prostanoid receptors and the urogenital tract. (2003) (7)
- Genomic structure and genitourinary expression of mouse cytosolic prostaglandin E(2) synthase gene. (2003) (6)
- Mechanism and regulation of proton transport in the outer medullary collecting duct. (1991) (6)
- Evidence for basolateral membrane Ca2+/H+ exchange in outer medullary collecting duct. (1993) (5)
- Pathological and Transcriptome Changes in the ReninAAV db/db uNx Model of Advanced Diabetic Kidney Disease Exhibit Features of Human Disease (2018) (5)
- Expression of a novel sodium-hydrogen exchanger in the gastrointestinal tract and kidney (1995) (5)
- Examining diabetic nephropathy through the lens of mouse genetics (2007) (5)
- Diabetic nephropathy: introduction. (2007) (5)
- Renal Medullary Interstitial Cells (2007) (5)
- Getting to the heart of COX-2 inhibition. (2005) (5)
- Osteopontin in diabetic nephropathy: signpost or road? (2010) (5)
- Effect of vasopressin on intracellular Na+ concentration in cortical collecting duct. (1996) (4)
- Progress in progression? (2010) (4)
- Translating experimental diabetic nephropathy studies from mice to men. (2011) (3)
- Characterization of the Proton‐Secreting Cell of the Rabbit Medullary Collecting Duct (1989) (3)
- Targeted gene disruption of the prostaglandin E2 EP2 receptor (1999) (3)
- Markers of Glycemic Control in the Mouse: Comparisons of Six- (2008) (3)
- prostaglandin EP3 receptor (1993) (3)
- Diabetic nephropathy: big and bad. (2005) (3)
- Intrarenal distribution of rabbit PKC zeta. (1997) (3)
- The Use of Genomics To Drive Kidney Disease Drug Discovery and Development. (2020) (3)
- Faculty Opinions recommendation of Recruitment of podocytes from glomerular parietal epithelial cells. (2009) (2)
- Structure and localization of the rabbit prostaglandin EP3 receptor. (1997) (1)
- Abstract 5439: Metabolomic study of EGFR drug resistance mechanisms (2014) (1)
- Eicosanoids and Renal Function (2013) (1)
- Cyclooxygenase-2 contributes to diabetic nephropathy through glomerular EP4 receptor. (2022) (1)
- Cloning and expression of the rabbit prostaglandin EP 2 receptor (2015) (1)
- Molecular Stratification of Chronic Kidney Disease (2021) (1)
- Generation and Activity of a Humanized Monoclonal Antibody that Selectively Neutralizes the Epidermal Growth Factor Receptor Ligands TGF-alpha and Epiregulin (2014) (1)
- Glycogen Synthase Kinase 3 Inhibition Improves Insulin Stimulated Glucose Metabolismin High Fat Fed C57/BL6J Mice (2007) (1)
- Beyond cyclooxygenase. (2002) (1)
- Type II cAMP-dependent protein kinase regulates electrogenic ion transport in rabbit collecting duct. (1999) (1)
- Erratum. Profibrotic Circulating Proteins and Risk of Early Progressive Renal Decline in Patients With Type 2 Diabetes With and Without Albuminuria. Diabetes Care 2020;43:2760–2767 (2020) (1)
- Faculty Opinions recommendation of In patients with type 1 diabetes and new-onset microalbuminuria the development of advanced chronic kidney disease may not require progression to proteinuria. (2010) (0)
- Induction of ABCA1 Expression by Liver X Receptor (LXR) agonist in Renal Glomerular Mesangial Cells (2006) (0)
- Sirtuin‐1‐dependent COX2 Induction is an Essential Survival Mechanism in Renal Medullary Interstitial Cells against Oxidative Stress (2009) (0)
- The Role of Prostaglandin EP1 and FP Receptors in the Regulation of Blood Pressure (2006) (0)
- Faculty Opinions recommendation of Activated signal transduction kinases frequently occupy target genes. (2006) (0)
- Faculty Opinions recommendation of Association of trypanolytic ApoL1 variants with kidney disease in African Americans. (2010) (0)
- FP266GROWTH DIFFERENTIATION FACTOR 15 IS A NOVEL BIOMARKER FOR PREDICTION OF RENAL OUTCOMES IN CHRONIC KIDNEY DISEASE (2015) (0)
- Faculty Opinions recommendation of A ligand-independent VEGFR2 signaling pathway limits angiogenic responses in diabetes. (2014) (0)
- Peroxisome proliferator-activated receptor γ (PPARγ) activity is associated with the renal microvasculature (2001) (0)
- Liver X receptor (LXR) agonist TO‐901317 restores renal fatty acid synthase (FAS) expression in db/db mice (2007) (0)
- Faculty Opinions recommendation of Blood pressure influences end-stage renal disease of Cd151 knockout mice. (2012) (0)
- Review for "Improving Residual Risk of Renal and Cardiovascular Outcomes in Diabetic Kidney Disease: Review of Pathophysiology, Mechanisms and Evidence from Recent Trials" (2021) (0)
- Abstract MP16: ReninAAV Uninephrectomized db/db Mice as a Novel Diabetic Kidney Diesease Model for Testing New Therapeutics on Top of RAS Inhibition (2015) (0)
- Cyclooxygenase-2 regulates renal medullary blood flow and urinary sodium excretion (2001) (0)
- DMM023036 1171..1174 (2015) (0)
- Increased dietary sodium induces COX2 expression by activating NFκB in renal medullary interstitial cells (2013) (0)
- Faculty Opinions recommendation of Evidence for hormonal control of heart regenerative capacity during endothermy acquisition. (2019) (0)
- in urinary tract of rabbits and humans Expression of peroxisome proliferator-activated receptors (2016) (0)
- Faculty Opinions recommendation of The natriuretic peptide/guanylyl cyclase--a system functions as a stress-responsive regulator of angiogenesis in mice. (2009) (0)
- Profibrotic circulating proteins and risk of early progressive renal decline in Type 2 Diabetes patients with and without albuminuria (2020) (0)
- Selective targeting of cyclooxygenase-2 reveals its role in renal medullary interstitial cell survival. (1999) (0)
- Abstract 1866: Stable isotope resolved metabolomics of colorectal cancer cells treated with inhibitor of monocarboxylate transporter-1. (2013) (0)
- Faculty Opinions recommendation of Cyclooxygenases, microsomal prostaglandin E synthase-1, and cardiovascular function. (2006) (0)
- Faculty Opinions recommendation of Prolactin alters blood pressure by modulating the activity of endothelial nitric oxide synthase. (2016) (0)
- Tackling AKI. (2023) (0)
- Mitochondrial and NAD+ metabolism predict recovery from acute kidney injury in a diverse mouse population (2023) (0)
- expression in rat renal medulla Mineralocorticoid regulation of cyclooxygenase-2 (2016) (0)
- Regulation of Potassium Excretion in FP Knockout Mice (2007) (0)
- Does Malfunction of Arachidonic Acid Epoxygenase Explain Salt-Sensitive Hypertension?: Salt-Sensitive Hypertension Is Associated with Dysfunctional Cyp4a10 Gene and Kidney Epithelial Sodium Channel. J Clin Invest 116: 1696-1702, 2006. (2006) (0)
- Faculty Opinions recommendation of Mature induced-pluripotent-stem-cell-derived human podocytes reconstitute kidney glomerular-capillary-wall function on a chip. (2017) (0)
- Faculty Opinions recommendation of Impaired basolateral sorting of pro-EGF causes isolated recessive renal hypomagnesemia. (2007) (0)
- 1654PNSCLC patient immune cell profiling and response of tumor antigen specific CD8 T cells to checkpoint receptor antagonists (2017) (0)
- Type II cAMP-dependent protein kinase regulates electrogenic ion transport in rabbit collecting duct. (1999) (0)
- Chapter 22 – Diabetic Nephropathy (2008) (0)
- Faculty Opinions recommendation of Interaction between Epithelial Sodium Channel γ-Subunit and Claudin-8 Modulates Paracellular Sodium Permeability in Renal Collecting Duct. (2020) (0)
- fibrates are used in this setting, renal function should be Drs. Broeders and Abramowicz made the clinically im- closely monitored. portant point that administration of fibrates to patients (2001) (0)
- High Sodium Diet Activated NFκB Signaling Plays an Important Role in Renal Medullary COX2 Induction (2009) (0)
- invited review Prostaglandin E receptors and the kidney (2000) (0)
- A Novel Aldosterone Antagonist Limits Renal Injury in 5/6 Nephrectomy (2017) (0)
- mice Mx1Cre vascular endothelium, and viscera of Differential, inducible gene targeting in renal epithelia, (2016) (0)
- Clinical Trials in Diabetic Kidney Disease: Opportunities and Obstacles (2015) (0)
- Faculty Opinions recommendation of CD4+CD25+ regulatory T cells attenuate cisplatin-induced nephrotoxicity in mice. (2010) (0)
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What Schools Are Affiliated With Matthew D. Breyer?
Matthew D. Breyer is affiliated with the following schools: