Matthew Meyerson

Q: What Schools Are Affiliated With Matthew Meyerson

Matthew Meyerson is affiliated with the following schools: MD Anderson Cancer Center, Tufts University, University of Valencia, Stanford University, University of Siena, University of Toronto, University of North Carolina at Chapel Hill, Massachusetts General Hospital, Harvard University

Matthew Meyerson's AcademicInfluence.com Rankings

Matthew Meyerson

Biology

#3362

World Rank

#5151

Historical Rank

Pathology

#42

World Rank

#96

Historical Rank

biology Degrees

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Biology

Matthew Meyerson's Degrees

Doctorate Medicine Harvard University
PhD Genetics Harvard University

Why Is Matthew Meyerson Influential?

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According to Wikipedia, Matthew Langer Meyerson is an American pathologist and the Charles A. Dana Chair in Human Cancer Genetics at the Dana-Farber Cancer Institute. He is also director of the Center for Cancer Genomics at the Dana-Farber Cancer Institute, and the Director of Cancer Genomics at the Broad Institute of MIT and Harvard.

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Matthew Meyerson's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy (2004) (9387)
Comprehensive molecular portraits of human breast tumors (2012) (7791)
Signatures of mutational processes in human cancer (2013) (7589)
Integrated Genomic Analyses of Ovarian Carcinoma (2011) (6411)
Comprehensive molecular characterization of human colon and rectal cancer (2012) (6141)
The Cancer Cell Line Encyclopedia enables predictive modeling of anticancer drug sensitivity (2012) (6062)
Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. (2010) (5816)
Comprehensive genomic characterization defines human glioblastoma genes and core pathways (2008) (5775)
Comprehensive molecular characterization of gastric adenocarcinoma (2014) (4496)
Comprehensive molecular profiling of lung adenocarcinoma (2014) (4095)
EGFR mutation and resistance of non-small-cell lung cancer to gefitinib. (2005) (3818)
Integrated genomic characterization of endometrial carcinoma (2013) (3708)
The Somatic Genomic Landscape of Glioblastoma (2013) (3693)
Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples (2013) (3663)
The landscape of somatic copy-number alteration across human cancers (2010) (3297)
Comprehensive genomic characterization of squamous cell lung cancers (2012) (2998)
Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. (2005) (2933)
Comprehensive genomic characterization of head and neck squamous cell carcinomas (2015) (2860)
Mutational heterogeneity in cancer and the search for new cancer-associated genes (2013) (2852)
The Immune Landscape of Cancer (2018) (2766)
Mutational heterogeneity in cancer and the search for new cancer genes (2013) (2691)
Somatic mutations affect key pathways in lung adenocarcinoma (2008) (2640)
Discovery and saturation analysis of cancer genes across 21 tumor types (2014) (2530)
The Mutational Landscape of Head and Neck Squamous Cell Carcinoma (2011) (2301)
Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1 (2009) (2300)
GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers (2011) (2261)
A Landscape of Driver Mutations in Melanoma (2012) (2244)
Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas. (2015) (2211)
Genomic Classification of Cutaneous Melanoma (2015) (2143)
The Molecular Taxonomy of Primary Prostate Cancer (2015) (2116)
Integrated Genomic Characterization of Papillary Thyroid Carcinoma (2014) (2007)
hEST2, the Putative Human Telomerase Catalytic Subunit Gene, Is Up-Regulated in Tumor Cells and during Immortalization (1997) (1879)
Comprehensive molecular characterization of urothelial bladder carcinoma (2014) (1748)
The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP (2008) (1741)
Comprehensive molecular characterization of clear cell renal cell carcinoma (2013) (1724)
Oncogenic Signaling Pathways in The Cancer Genome Atlas (2018) (1646)
Fusobacterium nucleatum potentiates intestinal tumorigenesis and modulates the tumor-immune microenvironment. (2013) (1628)
Mapping the Hallmarks of Lung Adenocarcinoma with Massively Parallel Sequencing (2012) (1620)
Absolute quantification of somatic DNA alterations in human cancer (2012) (1607)
Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients (2015) (1561)
Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses (2001) (1518)
Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma (2017) (1514)
Pan-cancer patterns of somatic copy-number alteration (2013) (1501)
Genomic analysis identifies association of Fusobacterium with colorectal carcinoma. (2012) (1492)
Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma (2016) (1474)
Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma (2005) (1458)
Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer (2017) (1446)
Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses. (2001) (1413)
Initial genome sequencing and analysis of multiple myeloma (2011) (1385)
Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer (2012) (1367)
Comprehensive Characterization of Cancer Driver Genes and Mutations (2018) (1360)
Comprehensive Molecular Portraits of Invasive Lobular Breast Cancer (2015) (1332)
Evolution and Impact of Subclonal Mutations in Chronic Lymphocytic Leukemia (2012) (1297)
BIBW2992, an irreversible EGFR/HER2 inhibitor highly effective in preclinical lung cancer models (2008) (1286)
The genomic complexity of primary human prostate cancer (2010) (1195)
Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer (2012) (1151)
Sequence analysis of mutations and translocations across breast cancer subtypes (2012) (1133)
Characterizing the cancer genome in lung adenocarcinoma (2007) (1122)
Punctuated Evolution of Prostate Cancer Genomes (2013) (1105)
Advances in understanding cancer genomes through second-generation sequencing (2010) (1104)
SF3B1 and other novel cancer genes in chronic lymphocytic leukemia. (2011) (1098)
Integrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma. (2017) (1092)
Gene expression–based survival prediction in lung adenocarcinoma: a multi-site, blinded validation study (2008) (1063)
Assessing the significance of chromosomal aberrations in cancer: Methodology and application to glioma (2007) (1052)
Inhibition of telomerase limits the growth of human cancer cells (1999) (1051)
High-throughput oncogene mutation profiling in human cancer (2007) (1041)
Activation of the PD-1 pathway contributes to immune escape in EGFR-driven lung tumors. (2013) (1025)
LKB1 modulates lung cancer differentiation and metastasis (2007) (975)
Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes (2018) (974)
Recurrent BRAF mutations in Langerhans cell histiocytosis. (2010) (948)
Amplification of phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis (2011) (942)
The genetic landscape of high-risk neuroblastoma (2013) (938)
Dissecting therapeutic resistance to RAF inhibition in melanoma by tumor genomic profiling. (2011) (938)
Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma. (2016) (931)
EML4-ALK Fusion Gene and Efficacy of an ALK Kinase Inhibitor in Lung Cancer (2008) (923)
Structures of lung cancer-derived EGFR mutants and inhibitor complexes: mechanism of activation and insights into differential inhibitor sensitivity. (2007) (914)
SOX2 Is an Amplified Lineage Survival Oncogene in Lung and Esophageal Squamous Cell Carcinomas (2009) (904)
A family of human cdc2‐related protein kinases. (1992) (899)
Identification of G1 kinase activity for cdk6, a novel cyclin D partner (1994) (870)
Activating mutations in ALK provide a therapeutic target in neuroblastoma (2008) (830)
A Tumor Suppressor Complex with GAP Activity for the Rag GTPases That Signal Amino Acid Sufficiency to mTORC1 (2013) (829)
Distinct patterns of somatic genome alterations in lung adenocarcinomas and squamous cell carcinomas (2016) (826)
Distinct patterns of somatic genome alterations in lung adenocarcinomas and squamous cell carcinomas (2016) (826)
CHROMOTHRIPSIS FROM DNA DAMAGE IN MICRONUCLEI (2015) (822)
Analysis of Fusobacterium persistence and antibiotic response in colorectal cancer (2017) (779)
Dissecting the genomic complexity underlying medulloblastoma (2012) (777)
Integrated genomic and molecular characterization of cervical cancer (2017) (762)
Subgroup-specific structural variation across 1,000 medulloblastoma genomes (2012) (760)
Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets. (2015) (727)
Melanoma genome sequencing reveals frequent PREX2 mutations (2012) (695)
MEDULLOBLASTOMA EXOME SEQUENCING UNCOVERS SUBTYPE-SPECIFIC SOMATIC MUTATIONS (2012) (686)
PF00299804, an irreversible pan-ERBB inhibitor, is effective in lung cancer models with EGFR and ERBB2 mutations that are resistant to gefitinib. (2007) (677)
Landscape of genomic alterations in cervical carcinomas (2013) (676)
Pivotal role of mTOR signaling in hepatocellular carcinoma. (2008) (675)
Oncogenic Transformation by Inhibitor-Sensitive and -Resistant EGFR Mutants (2005) (656)
Subtype-specific genomic alterations define new targets for soft tissue sarcoma therapy (2010) (653)
The somatic genomic landscape of chromophobe renal cell carcinoma. (2014) (646)
Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome. (2011) (643)
CDK8 is a colorectal cancer oncogene that regulates β-catenin activity (2008) (630)
Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locus. (2004) (622)
Fusobacterium nucleatum in colorectal carcinoma tissue and patient prognosis (2015) (616)
Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells (2004) (614)
Integrative Genomic Approaches Identify IKBKE as a Breast Cancer Oncogene (2007) (613)
An integrated view of copy number and allelic alterations in the cancer genome using single nucleotide polymorphism arrays. (2004) (583)
Genomic and Functional Approaches to Understanding Cancer Aneuploidy. (2018) (578)
Comprehensive and Integrated Genomic Characterization of Adult Soft Tissue Sarcomas (2017) (577)
Focal gains of VEGFA and molecular classification of hepatocellular carcinoma. (2008) (566)
Highly parallel identification of essential genes in cancer cells (2008) (553)
Exon 19 Deletion Mutations of Epidermal Growth Factor Receptor Are Associated with Prolonged Survival in Non–Small Cell Lung Cancer Patients Treated with Gefitinib or Erlotinib (2006) (549)
High-resolution mapping of copy-number alterations with massively parallel sequencing (2009) (540)
TMPRSS2:ERG fusion-associated deletions provide insight into the heterogeneity of prostate cancer. (2006) (539)
Genetic and transcriptional evolution alters cancer cell line drug response (2018) (536)
Comprehensive genomic analysis of rhabdomyosarcoma reveals a landscape of alterations affecting a common genetic axis in fusion-positive and fusion-negative tumors. (2014) (521)
The Menin Tumor Suppressor Protein Is an Essential Oncogenic Cofactor for MLL-Associated Leukemogenesis (2005) (518)
Prognostically relevant gene signatures of high-grade serous ovarian carcinoma. (2012) (509)
Pathogenic Germline Variants in 10,389 Adult Cancers (2018) (501)
PTEN loss contributes to erlotinib resistance in EGFR-mutant lung cancer by activation of Akt and EGFR. (2009) (495)
Whole exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer (2014) (479)
High-throughput detection of actionable genomic alterations in clinical tumor samples by targeted, massively parallel sequencing. (2012) (478)
Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer. (2011) (474)
Activating Mutations of the Noonan Syndrome-Associated SHP2/PTPN11 Gene in Human Solid Tumors and Adult Acute Myelogenous Leukemia (2004) (472)
Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients (2018) (471)
Scalable whole-exome sequencing of cell-free DNA reveals high concordance with metastatic tumors (2017) (469)
Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors. (2005) (466)
Telomerase activity is restored in human cells by ectopic expression of hTERT (hEST2), the catalytic subunit of telomerase (1998) (440)
Profiling Critical Cancer Gene Mutations in Clinical Tumor Samples (2009) (439)
Whole exome sequencing identifies a recurrent NAB2-STAT6 fusion in solitary fibrous tumors (2013) (437)
Prognostic and predictive gene signature for adjuvant chemotherapy in resected non-small-cell lung cancer. (2010) (437)
Genomic Copy Number Dictates a Gene-Independent Cell Response to CRISPR/Cas9 Targeting. (2016) (436)
Commensal Microbiota Promote Lung Cancer Development via γδ T Cells (2019) (431)
Oncotator: Cancer Variant Annotation Tool (2015) (428)
Mutational signature in colorectal cancer caused by genotoxic pks+E. coli (2020) (426)
Structural, Biochemical, and Clinical Characterization of Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertion Mutations in Lung Cancer (2013) (419)
Isolation of the human cdk2 gene that encodes the cyclin A- and adenovirus E1A-associated p33 kinase (1991) (419)
Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer (2011) (412)
Suppression of Lung Adenocarcinoma Progression by Nkx2-1 (2011) (408)
Expression of TERT in early premalignant lesions and a subset of cells in normal tissues (1998) (404)
Patterns of gene expression and copy-number alterations in von-hippel lindau disease-associated and sporadic clear cell carcinoma of the kidney. (2009) (392)
Menin regulates pancreatic islet growth by promoting histone methylation and expression of genes encoding p27Kip1 and p18INK4c. (2005) (390)
Patterns of somatic structural variation in human cancer genomes (2020) (377)
Patterns of somatic structural variation in human cancer genomes (2020) (377)
Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA , IDH 1 , EGFR , and NF 1 Citation Verhaak (2010) (362)
Inhibitor-Sensitive FGFR1 Amplification in Human Non-Small Cell Lung Cancer (2011) (357)
Sensitive mutation detection in heterogeneous cancer specimens by massively parallel picoliter reactor sequencing (2006) (354)
Gefitinib Induces Apoptosis in the EGFRL858R Non–Small-Cell Lung Cancer Cell Line H3255 (2004) (353)
Lin28 Enhances Tumorigenesis and is Associated With Advanced Human Malignancies (2009) (349)
Drug-sensitive FGFR2 mutations in endometrial carcinoma (2008) (346)
Epidermal Growth Factor Receptor Activation in Glioblastoma through Novel Missense Mutations in the Extracellular Domain (2006) (345)
Homozygous deletions and chromosome amplifications in human lung carcinomas revealed by single nucleotide polymorphism array analysis. (2005) (341)
The kinesin KIF1Bbeta acts downstream from EglN3 to induce apoptosis and is a potential 1p36 tumor suppressor. (2008) (330)
Making sense of cancer genomic data. (2011) (326)
Genome coverage and sequence fidelity of phi29 polymerase-based multiple strand displacement whole genome amplification. (2004) (318)
Phase II clinical trial of chemotherapy-naive patients > or = 70 years of age treated with erlotinib for advanced non-small-cell lung cancer. (2007) (309)
Whole-genome and multisector exome sequencing of primary and post-treatment glioblastoma reveals patterns of tumor evolution (2015) (307)
Loss-of-heterozygosity analysis of small-cell lung carcinomas using single-nucleotide polymorphism arrays (2000) (307)
Institutional implementation of clinical tumor profiling on an unselected cancer population. (2016) (303)
Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion (2011) (298)
Characterization of HPV and host genome interactions in primary head and neck cancers (2014) (296)
Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma. (2016) (295)
Modeling genomic diversity and tumor dependency in malignant melanoma. (2008) (294)
Patient-derived lung cancer organoids as in vitro cancer models for therapeutic screening (2019) (289)
Integrative analysis of the melanoma transcriptome. (2010) (288)
Discovering the anticancer potential of non-oncology drugs by systematic viability profiling (2020) (287)
Missense mutations of the BRAF gene in human lung adenocarcinoma. (2002) (286)
Somatic mutation of CDKN1B in small intestine neuroendocrine tumors (2013) (282)
Targeted genomic rearrangements using CRISPR/Cas technology (2014) (280)
Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer (2018) (277)
Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions. (2009) (275)
Integrated genomic profiling of endometrial carcinoma associates aggressive tumors with indicators of PI3 kinase activation (2009) (274)
The Parafibromin Tumor Suppressor Protein Is Part of a Human Paf1 Complex (2005) (270)
Therapeutic targeting of oncogenic K-Ras by a covalent catalytic site inhibitor. (2014) (269)
PathSeq: software to identify or discover microbes by deep sequencing of human tissue (2011) (268)
Gene expression profiling reveals reproducible human lung adenocarcinoma subtypes in multiple independent patient cohorts. (2006) (267)
Functional analysis of receptor tyrosine kinase mutations in lung cancer identifies oncogenic extracellular domain mutations of ERBB2 (2012) (267)
An alternative inhibitor overcomes resistance caused by a mutation of the epidermal growth factor receptor. (2005) (266)
Identification of focally amplified lineage-specific super-enhancers in human epithelial cancers (2015) (265)
Integrated Genome-Wide DNA Copy Number and Expression Analysis Identifies Distinct Mechanisms of Primary Chemoresistance in Ovarian Carcinomas (2009) (265)
Integrated Molecular Characterization of Testicular Germ Cell Tumors (2018) (261)
Gastrointestinal adenocarcinomas of the esophagus, stomach, and colon exhibit distinct patterns of genome instability and oncogenesis. (2012) (260)
Epidermal growth factor receptor variant III mutations in lung tumorigenesis and sensitivity to tyrosine kinase inhibitors (2006) (253)
The catalytic subunit of yeast telomerase. (1997) (250)
Recurrent and functional regulatory mutations in breast cancer (2017) (249)
Mutational processes shape the landscape of TP53 mutations in human cancer (2018) (244)
Whole-exome sequencing reveals frequent genetic alterations in BAP1, NF2, CDKN2A, and CUL1 in malignant pleural mesothelioma. (2015) (243)
Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma. (2016) (241)
Signal transducer and activator of transcription 3 is required for the oncogenic effects of non-small-cell lung cancer-associated mutations of the epidermal growth factor receptor. (2006) (237)
EGFR variant heterogeneity in glioblastoma resolved through single-nucleus sequencing. (2014) (237)
The Human Tumor Atlas Network: Charting Tumor Transitions across Space and Time at Single-Cell Resolution (2020) (234)
SvABA: genome-wide detection of structural variants and indels by local assembly (2017) (226)
A Rapid and Sensitive Enzymatic Method for Epidermal Growth Factor Receptor Mutation Screening (2006) (221)
Genomic basis for RNA alterations in cancer (2020) (221)
Structural Alterations Driving Castration-Resistant Prostate Cancer Revealed by Linked-Read Genome Sequencing (2018) (221)
Analyses of non-coding somatic drivers in 2,658 cancer whole genomes (2020) (220)
Bronchial and peripheral murine lung carcinomas induced by T790M-L858R mutant EGFR respond to HKI-272 and rapamycin combination therapy. (2007) (219)
An activated ErbB3/NRG1 autocrine loop supports in vivo proliferation in ovarian cancer cells. (2010) (212)
Fusobacterium nucleatum in Colorectal Carcinoma Tissue According to Tumor Location (2016) (211)
Loss of Heterozygosity and Its Correlation with Expression Profiles in Subclasses of Invasive Breast Cancers (2004) (205)
Role of telomerase in normal and cancer cells. (2000) (202)
Comprehensive molecular characterization of mitochondrial genomes in human cancers (2017) (197)
Nkx2-1 represses a latent gastric differentiation program in lung adenocarcinoma. (2013) (196)
Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context (2018) (188)
SOX2 gene amplification and protein overexpression are associated with better outcome in squamous cell lung cancer (2011) (186)
HER2YVMA drives rapid development of adenosquamous lung tumors in mice that are sensitive to BIBW2992 and rapamycin combination therapy (2009) (185)
Recurrent Hemizygous Deletions in Cancers May Optimize Proliferative Potential (2012) (181)
Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition (2020) (180)
Inferring Loss-of-Heterozygosity from Unpaired Tumors Using High-Density Oligonucleotide SNP Arrays (2006) (177)
Response to treatment and survival of patients with non-small cell lung cancer undergoing somatic EGFR mutation testing. (2007) (176)
Interlaboratory comparability study of cancer gene expression analysis using oligonucleotide microarrays. (2005) (173)
The multifunctional protein p54nrb/PSF recruits the exonuclease XRN2 to facilitate pre-mRNA 3' processing and transcription termination. (2007) (172)
Somatic retrotransposition in human cancer revealed by whole-genome and exome sequencing (2014) (172)
Hsp90 inhibition suppresses mutant EGFR-T790M signaling and overcomes kinase inhibitor resistance. (2008) (171)
Functional Copy-Number Alterations in Cancer (2008) (170)
Epidermal growth factor-independent transformation of Ba/F3 cells with cancer-derived epidermal growth factor receptor mutants induces gefitinib-sensitive cell cycle progression. (2005) (167)
Integrative and comparative genomic analysis of lung squamous cell carcinomas in East Asian patients. (2014) (166)
BreaKmer: detection of structural variation in targeted massively parallel sequencing data using kmers (2014) (162)
Somatic alterations in the human cancer genome. (2004) (162)
Inhibitor-sensitive FGFR2 and FGFR3 mutations in lung squamous cell carcinoma. (2013) (161)
High-throughput Phenotyping of Lung Cancer Somatic Mutations. (2016) (157)
A Pan-Cancer Analysis of Transcriptome Changes Associated with Somatic Mutations in U2AF1 Reveals Commonly Altered Splicing Events (2014) (155)
Mutations in the LKB1 tumour suppressor are frequently detected in tumours from Caucasian but not Asian lung cancer patients (2008) (152)
A functional landscape of resistance to ALK inhibition in lung cancer. (2015) (151)
Nuclear factor I/B is an oncogene in small cell lung cancer. (2011) (147)
Transcriptomic Characterization of SF3B1 Mutation Reveals Its Pleiotropic Effects in Chronic Lymphocytic Leukemia. (2016) (147)
Prognostic Impact of Novel Molecular Subtypes of Small Intestinal Neuroendocrine Tumor (2015) (144)
Ganetespib (STA-9090), a Nongeldanamycin HSP90 Inhibitor, Has Potent Antitumor Activity in In Vitro and In Vivo Models of Non–Small Cell Lung Cancer (2012) (144)
Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1 (2011) (143)
Genome-wide loss of heterozygosity analysis from laser capture microdissected prostate cancer using single nucleotide polymorphic allele (SNP) arrays and a novel bioinformatics platform dChipSNP. (2003) (138)
Updated Frequency of EGFR and KRAS Mutations in NonSmall-Cell Lung Cancer in Latin America: The Latin-American Consortium for the Investigation of Lung Cancer (CLICaP) (2015) (138)
SOX2 and p63 colocalize at genetic loci in squamous cell carcinomas. (2014) (136)
Unique, dual-indexed sequencing adapters with UMIs effectively eliminate index cross-talk and significantly improve sensitivity of massively parallel sequencing (2018) (136)
The Somatic Genomic Landscape of Glioblastoma (2014) (135)
Germline cancer susceptibility gene variants, somatic second hits, and survival outcomes in patients with resected pancreatic cancer (2018) (134)
Non-small-cell lung cancer and Ba/F3 transformed cells harboring the ERBB2 G776insV_G/C mutation are sensitive to the dual-specific epidermal growth factor receptor and ERBB2 inhibitor HKI-272. (2006) (134)
Telomerase activation, cellular immortalization and cancer (2001) (134)
High-order chromatin architecture shapes the landscape of chromosomal alterations in cancer (2012) (134)
Sequence-based discovery of Bradyrhizobium enterica in cord colitis syndrome. (2013) (133)
Somatic rearrangements across cancer reveal classes of samples with distinct patterns of DNA breakage and rearrangement-induced hypermutability (2012) (132)
The tumor suppressor Cdc73 functionally associates with CPSF and CstF 3′ mRNA processing factors (2009) (129)
Allele-Specific Amplification in Cancer Revealed by SNP Array Analysis (2005) (128)
Disruption of chromatin folding domains by somatic genomic rearrangements in human cancer (2020) (128)
A structure-guided approach to creating covalent FGFR inhibitors. (2010) (127)
High-resolution single-nucleotide polymorphism array and clustering analysis of loss of heterozygosity in human lung cancer cell lines (2004) (125)
Genome-Wide Analysis of Neuroblastomas using High-Density Single Nucleotide Polymorphism Arrays (2007) (125)
Amplification of CRKL induces transformation and epidermal growth factor receptor inhibitor resistance in human non-small cell lung cancers. (2011) (122)
Exome sequencing of pleuropulmonary blastoma reveals frequent biallelic loss of TP53 and two hits in DICER1 resulting in retention of 5p-derived miRNA hairpin loop sequences (2014) (122)
ERG rearrangement is specific to prostate cancer and does not occur in any other common tumor (2010) (121)
Genetic interrogation of circulating multiple myeloma cells at single-cell resolution (2016) (121)
Identification of ADAR1 adenosine deaminase dependency in a subset of cancer cells (2018) (118)
Addendum: The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity (2018) (117)
A novel totivirus and piscine reovirus (PRV) in Atlantic salmon (Salmo salar) with cardiomyopathy syndrome (CMS) (2010) (115)
Near universal detection of alterations in CTNNB1 and Wnt pathway regulators in desmoid‐type fibromatosis by whole‐exome sequencing and genomic analysis (2015) (115)
The major lung cancer-derived mutants of ERBB2 are oncogenic and are associated with sensitivity to the irreversible EGFR/ERBB2 inhibitor HKI-272 (2007) (113)
Germline and somatic BAP1 mutations in high-grade rhabdoid meningiomas (2016) (113)
Transcriptional profiling identifies cyclin D1 as a critical downstream effector of mutant epidermal growth factor receptor signaling. (2006) (111)
Clinical significance of TTF‐1 protein expression and TTF‐1 gene amplification in lung adenocarcinoma (2009) (106)
Cancer Genomes Evolve by Pulverizing Single Chromosomes (2011) (106)
Integrative radiogenomic profiling of squamous cell lung cancer. (2013) (106)
SF 3 B 1 and Other Novel Cancer Genes in Chronic Lymphocytic Leukemia (2011) (106)
Fusobacterium nucleatum in Colorectal Cancer Relates to Immune Response Differentially by Tumor Microsatellite Instability Status (2018) (103)
Association of Alterations in Main Driver Genes With Outcomes of Patients With Resected Pancreatic Ductal Adenocarcinoma (2017) (100)
High-throughput sequence analysis of the tyrosine kinome in acute myeloid leukemia. (2007) (99)
SHP2 tyrosine phosphatase converts parafibromin/Cdc73 from a tumor suppressor to an oncogenic driver. (2011) (96)
Identifying and characterizing a novel activating mutation of the FLT3 tyrosine kinase in AML. (2004) (96)
Distinct genomic aberrations associated with ERG rearranged prostate cancer (2009) (93)
Genomic and immune profiling of pre-invasive lung adenocarcinoma (2019) (90)
Insertions and Deletions Target Lineage-Defining Genes in Human Cancers (2017) (90)
Oncogenic and sorafenib-sensitive ARAF mutations in lung adenocarcinoma. (2014) (89)
Erratum: Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles (Cell Reports (2017) 18(11) (2780–2794) (S2211124717302140) (10.1016/j.celrep.2017.02.033)) (2017) (88)
Amplification of chromosomal segment 4q12 in non-small cell lung cancer (2009) (87)
Genomic and proteomic profiling of lung cancers: lung cancer classification in the age of targeted therapy. (2005) (85)
Somatic Superenhancer Duplications and Hotspot Mutations Lead to Oncogenic Activation of the KLF5 Transcription Factor. (2017) (84)
Epidermal Growth Factor Receptor Mutation Testing in the Care of Lung Cancer Patients (2006) (84)
Activation of GATA binding protein 6 (GATA6) sustains oncogenic lineage-survival in esophageal adenocarcinoma (2012) (83)
High-order chromatin architecture determines the landscape of chromosomal alterations in cancer (2011) (82)
Allele-dependent variation in the relative cellular potency of distinct EGFR inhibitors (2007) (82)
TTF1 expression in non‐small cell lung carcinoma: association with TTF1 gene amplification and improved survival (2009) (80)
Whole Exome Sequencing Identifies TSC1/TSC2 Biallelic Loss as the Primary and Sufficient Driver Event for Renal Angiomyolipoma Development (2016) (80)
Suppression of Adaptive Responses to Targeted Cancer Therapy by Transcriptional Repression. (2017) (79)
Glioblastoma-derived epidermal growth factor receptor carboxyl-terminal deletion mutants are transforming and are sensitive to EGFR-directed therapies. (2011) (78)
Cetuximab response of lung cancer-derived EGF receptor mutants is associated with asymmetric dimerization. (2013) (77)
Detection of Somatic Structural Variants Enables Quantification and Characterization of Circulating Tumor DNA in Children With Solid Tumors. (2018) (77)
CDK 8 is a colorectal cancer oncogene that regulates b-catenin activity (2008) (77)
Predicting relapse in patients with medulloblastoma by integrating evidence from clinical and genomic features. (2011) (74)
Tumor fraction in cell-free DNA as a biomarker in prostate cancer. (2018) (74)
Clinical, genomic, and metagenomic characterization of oral tongue squamous cell carcinoma in patients who do not smoke (2015) (70)
Sensitive Detection of Minimal Residual Disease in Patients Treated for Early-Stage Breast Cancer (2020) (69)
Oncogenic RIT1 mutations in lung adenocarcinoma (2014) (68)
Molecular classification and molecular genetics of human lung cancers. (2004) (68)
Identification of cancer cytotoxic modulators of PDE3A by predictive chemogenomics (2015) (65)
Calibrating genomic and allelic coverage bias in single-cell sequencing (2015) (65)
Integrated cistromic and expression analysis of amplified NKX2-1 in lung adenocarcinoma identifies LMO3 as a functional transcriptional target. (2013) (64)
Identification of foreign gene sequences by transcript filtering against the human genome (2002) (64)
Rapid Intraoperative Molecular Characterization of Glioma. (2015) (64)
Abstract 1: Oncogenic extracellular domain mutations of ERBB2 in cancer (2012) (63)
Structure and mechanism of activity-based inhibition of the EGF-Receptor by Mig6 (2015) (61)
Comment on "The Consensus Coding Sequences of Human Breast and Colorectal Cancers" (2007) (59)
Distinct pathways regulated by menin and by MLL1 in hematopoietic stem cells and developing B cells. (2013) (58)
Erratum: Sensitive mutation detection in heterogeneous cancer specimens by massively parallel picoliter reactor sequencing (2006) (58)
Acquired Resistance to Dasatinib in Lung Cancer Cell Lines Conferred by DDR2 Gatekeeper Mutation and NF1 Loss (2013) (58)
Comparison of Prevalence and Types of Mutations in Lung Cancers Among Black and White Populations (2017) (58)
Sporadic hemangioblastomas are characterized by cryptic VHL inactivation (2014) (57)
The tumor virus landscape of AIDS-related lymphomas. (2015) (56)
Advances in Brief Gefitinib Induces Apoptosis in the EGFRL 858 R Non – Small-Cell Lung Cancer Cell Line H 3255 (2004) (55)
Genomic Activation of PPARG Reveals a Candidate Therapeutic Axis in Bladder Cancer. (2017) (55)
MET Exon 14 Mutation Encodes an Actionable Therapeutic Target in Lung Adenocarcinoma. (2017) (55)
Microbes and Inflammation in Colorectal Cancer (2013) (55)
GATK PathSeq: a customizable computational tool for the discovery and identification of microbial sequences in libraries from eukaryotic hosts (2018) (54)
Clinicopathological and genomic correlates of Programmed Cell Death Ligand 1 (PD-L1) expression in nonsquamous non-small cell lung cancer. (2020) (54)
Erratum: Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma (Cancer Cell (2016) 29(5) (723–736) (S153561081630160X) (10.1016/j.ccell.2016.04.002)) (2016) (54)
Transcriptional activators enhance polyadenylation of mRNA precursors. (2011) (53)
Mutations in the DDR 2 Kinase Gene identify a Novel therapeutic target in squamous cell lung cancer (2011) (53)
Genomic Profiling of Prostate Cancers from Men with African and European Ancestry (2020) (52)
BRAF alteration status and the histone H3F3A gene K27M mutation segregate spinal cord astrocytoma histology (2015) (51)
Pervasive generation of non-canonical subgenomic RNAs by SARS-CoV-2 (2020) (50)
Frequent HIN-1 promoter methylation and lack of expression in multiple human tumor types. (2004) (50)
Genomic Approaches to Lung Cancer (2006) (49)
Summary Statement: Novel Agents in the Treatment of Lung Cancer: Advances in Epidermal Growth Factor Receptor-Targeted Agents (2006) (49)
Erratum: The somatic genomic landscape of glioblastoma (Cell (2013) 155 (462-477)) (2014) (49)
Dynamic Epigenetic Regulation by Menin During Pancreatic Islet Tumor Formation (2014) (48)
Complete hematologic response of early T-cell progenitor acute lymphoblastic leukemia to the γ-secretase inhibitor BMS-906024: genetic and epigenetic findings in an outlier case (2015) (48)
Genetic modifiers of EGFR dependence in non-small cell lung cancer (2014) (48)
TSC1 loss synergizes with KRAS activation in lung cancer development in the mouse and confers rapamycin sensitivity (2009) (47)
Brief Report: In Search of a Candidate Pathogen for Giant Cell Arteritis: Sequencing‐Based Characterization of the Giant Cell Arteritis Microbiome (2014) (46)
Genome-scale analysis identifies paralog lethality as a vulnerability of chromosome 1p loss in cancer (2018) (45)
ROS1 rearrangements in lung cancer: a new genomic subset of lung adenocarcinoma. (2012) (44)
Clinical implementation of comprehensive strategies to characterize cancer genomes: opportunities and challenges. (2011) (44)
DNA sequencing of cancer: what have we learned? (2014) (43)
Pathogen discovery from human tissue by sequence-based computational subtraction. (2003) (42)
The Amount of Bifidobacterium Genus in Colorectal Carcinoma Tissue in Relation to Tumor Characteristics and Clinical Outcome. (2018) (42)
Major copy proportion analysis of tumor samples using SNP arrays (2008) (42)
Frequent downregulation of the transcription factor Foxa2 in lung cancer through epigenetic silencing. (2012) (41)
The Menin Tumor Suppressor Protein Is Phosphorylated in Response to DNA Damage (2011) (41)
SOS1 mutations are rare in human malignancies: Implications for Noonan syndrome patients (2008) (41)
Sex differences in oncogenic mutational processes (2019) (41)
Detection of oncogenic mutations in the EGFR gene in lung adenocarcinoma with differential sensitivity to EGFR tyrosine kinase inhibitors. (2005) (39)
HER-2/neu expression is associated with high tumor cell proliferation and aggressive phenotype in a population based patient series of endometrial carcinomas. (2008) (39)
Genomic discovery and clonal tracking in multiple myeloma by cell-free DNA sequencing (2018) (39)
Targeted therapy for squamous cell lung cancer. (2012) (39)
Copy number alterations unmasked as enhancer hijackers (2016) (38)
RAS–MAPK Reactivation Facilitates Acquired Resistance in FGFR1-Amplified Lung Cancer and Underlies a Rationale for Upfront FGFR–MEK Blockade (2018) (38)
Telomerase enzyme activation and human cell immortalization. (1998) (37)
Characterization of DDR2 Inhibitors for the Treatment of DDR2 Mutated Nonsmall Cell Lung Cancer (2015) (37)
Genetic ancestry contributes to somatic mutations in lung cancers from admixed Latin American populations (2020) (36)
Genomic aberrations in cervical adenocarcinomas in Hong Kong Chinese women (2015) (36)
"Lineage addiction" in human cancer: lessons from integrated genomics. (2005) (36)
Genotype-targeted local therapy of glioma (2018) (35)
Somatic mutations are present in all members of the AKT family in endometrial carcinoma (2009) (35)
High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations (2020) (34)
Colorectal Cancers from Distinct Ancestral Populations Show Variations in BRAF Mutation Frequency (2013) (33)
Kinase domain activation of FGFR2 yields high-grade lung adenocarcinoma sensitive to a Pan-FGFR inhibitor in a mouse model of NSCLC. (2014) (32)
Adding pathogens by genomic subtraction. (2008) (31)
Recurrent allelic deletions of chromosome arms 15q and 16q in human small cell lung carcinomas (2000) (30)
NSCLC Driven by DDR2 Mutation Is Sensitive to Dasatinib and JQ1 Combination Therapy (2015) (29)
The cyclin-dependent kinase family. (1991) (29)
EGFR gene mutations: a call for global x global views of cancer. (2005) (29)
Colon cancer-derived oncogenic EGFR G724S mutant identified by whole genome sequence analysis is dependent on asymmetric dimerization and sensitive to cetuximab (2014) (28)
Splicing modulation sensitizes chronic lymphocytic leukemia cells to venetoclax by remodeling mitochondrial apoptotic dependencies. (2018) (28)
Phosphorylation of the Menin Tumor Suppressor Protein on Serine 543 and Serine 583 (2006) (28)
Identification and Characterization of Oncogenic SOS1 Mutations in Lung Adenocarcinoma (2017) (28)
An Activated ErbB 3 / NRG 1 Autocrine Loop Supports In Vivo Proliferation in Ovarian Cancer Cells (27)
Non-oncology drugs are a source of previously unappreciated anti-cancer activity (2019) (27)
Genomic basis for RNA alterations revealed by whole-genome analyses of 27 cancer types (2017) (27)
Inhibitor-Sensitive FGFR 1 Amplification in Human Non-Small Cell Lung Cancer (2011) (26)
Malawi Polyomavirus Is a Prevalent Human Virus That Interacts with Known Tumor Suppressors (2014) (26)
Accurate estimation of homologue-specific DNA concentration-ratios in cancer samples allows long-range haplotyping (2011) (25)
A Functional Landscape of Resistance to MEK1/2 and CDK4/6 Inhibition in NRAS-Mutant Melanoma. (2019) (25)
Signatures of mutational processes in human cancer this access benefits you. Your matters (2013) (23)
DNA copy number analysis of metastatic urothelial carcinoma with comparison to primary tumors (2015) (23)
Illuminating the noncoding genome in cancer (2020) (23)
Genomic representations using concatenates of Type IIB restriction endonuclease digestion fragments. (2004) (22)
MITI minimum information guidelines for highly multiplexed tissue images (2021) (22)
In situ evidence of KRAS amplification and association with increased p21 levels in non-small cell lung carcinoma. (2009) (22)
Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples (2020) (22)
Reprogramming of the esophageal squamous carcinoma epigenome by SOX2 promotes ADAR1 dependence (2021) (22)
Metagenomic Characterization of Microbial Communities In Situ Within the Deeper Layers of the Ileum in Crohn’s Disease (2016) (22)
FGFR2 Extracellular Domain In-Frame Deletions are Therapeutically Targetable Genomic Alterations that Function as Oncogenic Drivers in Cholangiocarcinoma. (2021) (21)
Identification of an “Exceptional Responder” Cell Line to MEK1 Inhibition: Clinical Implications for MEK-Targeted Therapy (2015) (21)
VariantBam: filtering and profiling of next-generational sequencing data using region-specific rules (2016) (21)
Structure of PDE3A-SLFN12 complex reveals requirements for activation of SLFN12 RNase (2021) (21)
c-MET expression/activation, functions, and mutations in non-small cell lung cancer (2004) (21)
Multi-Omics Analysis Identifies MGA as a Negative Regulator of the MYC Pathway in Lung Adenocarcinoma (2019) (21)
Pooled Genomic Screens Identify Anti-apoptotic Genes as Targetable Mediators of Chemotherapy Resistance in Ovarian Cancer (2019) (20)
Cancer: Broken genes in solid tumours (2007) (19)
Whole-Exome Sequencing Reveals Frequent Genetic Alterations in BAP 1 , NF 2 , CDKN 2 A , and CUL 1 in Malignant Pleural Mesothelioma (2014) (19)
A 15-gene expression signature prognostic for survival and predictive for adjuvant chemotherapy benefit in JBR.10 patients (2008) (19)
Transcriptomic Characterization of SF 3 B 1 Mutation Reveals Its Pleiotropic Effects in Chronic Lymphocytic Leukemia (2016) (18)
Pan-cancer study of heterogeneous RNA aberrations (2017) (16)
Comprehensive genomic characterization of squamous cell carcinoma of the lung. (2012) (16)
C/EBPa mutations in lung cancer (2006) (15)
Author Correction: Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes (2018) (15)
Antigen identification for HLA class I– and HLA class II–restricted T cell receptors using cytokine-capturing antigen-presenting cells (2021) (14)
Emerging Concepts and Technologies for the Discovery of Microorganisms Involved in Human Disease. (2017) (14)
Recurrent hormone-binding domain truncated ESR1 amplifications in primary endometrial cancers suggest their implication in hormone independent growth (2016) (14)
SOX 2 and p 63 colocalize at genetic loci in squamous cell carcinomas (2014) (14)
Advances in Brief Activating Mutations of the Noonan Syndrome-Associated SHP 2 / PTPN 11 Gene in Human Solid Tumors and Adult Acute Myelogenous Leukemia (2004) (14)
A quantitative model for carbonyl infrared frequencies of substituted quinones (1985) (13)
High-throughput Phenotyping of Lung Cancer Somatic Mutations. (2016) (13)
in squamous cell lung cancer (2011) (13)
Corrigendum: Signatures of mutational processes in human cancer (2013) (13)
Distinct pathways affected by menin versus MLL1/MLL2 in MLL-rearranged acute myeloid leukemia. (2019) (13)
Human genetic variation and disease (2003) (12)
Hopping between differentiation states in lung adenocarcinoma. (2013) (12)
Patterns of chromosome 18 loss of heterozygosity in multifocal ileal neuroendocrine tumors (2020) (12)
Combined tumor and immune signals from genomes or transcriptomes predict outcomes of checkpoint inhibition in melanoma (2021) (12)
Inhibitor-Sensitive FGFR 2 and FGFR 3 Mutations in Lung Squamous Cell Carcinoma (2013) (12)
Optimization of PDE3A Modulators for SLFN12-Dependent Cancer Cell Killing. (2019) (12)
Kmt2a cooperates with menin to suppress tumorigenesis in mouse pancreatic islets (2016) (11)
C/EBP alpha mutations in lung cancer. (2006) (11)
Pan-ERBB kinase inhibition augments CDK4/6 inhibitor efficacy in oesophageal squamous cell carcinoma (2021) (11)
Integrated genomic correlates of response to PD-1 inhibitor nivolumab in metastatic renal cell carcinoma (mRCC). (2016) (11)
Genome-wide association study in esophageal squamous cell carcinoma. (2009) (11)
Identifying and correcting repeat-calling errors in nanopore sequencing of telomeres (2022) (11)
Molecular Characterization and Therapeutic Targeting of Colorectal Cancers Harboring Receptor Tyrosine Kinase Fusions (2021) (10)
A121: In Search of Infectious Triggers of Periodic Fever, Aphthous Stomatitis, Pharyngitis and Adenitis Syndrome (2014) (10)
Whole-genome characterization of lung adenocarcinomas lacking alterations in the RTK/RAS/RAF pathway (2021) (10)
Quantification of aneuploidy in targeted sequencing data using ASCETS (2020) (10)
Unusual cases in multiple myeloma and a dramatic response in metastatic lung cancer: case 4. Mutation of the epidermal growth factor receptor in an elderly man with advanced, gefitinib-responsive, non-small-cell lung cancer. (2016) (10)
Chromosomal Deletions and Progression of Premalignant Lesions: Less Is More (2008) (10)
Abstract 2: FGFR3 as a therapeutic target in squamous cell lung carcinoma (2012) (10)
Bradyrhizobium enterica in cord colitis syndrome. (2013) (10)
Endometrial Carcinoma Recurrence Score (ECARS) validates to identify aggressive disease and associates with markers of epithelial-mesenchymal transition and PI3K alterations. (2014) (9)
Epidermal Growth Factor – Independent Transformation of Ba / F 3 Cells with Cancer-Derived Epidermal Growth Factor Receptor Mutants Induces Gefitinib-Sensitive Cell Cycle Progression (2005) (9)
Comprehensive metagenomic analysis of blastic plasmacytoid dendritic cell neoplasm. (2020) (9)
Comprehensive Genetic Interrogation of Circulating Multiple Myeloma Cells at Single Cell Resolution (2016) (9)
Structural, biochemical, and clinical characterization of Epidermal Growth Factor Receptor (EGFR) exon 20 insertion mutations in lung cancer (Science Translational Medicine (2014) 6, (225er1)) (2014) (9)
Abstract 3933: Dissecting therapeutic resistance to RAF inhibition in melanoma by tumor genomic profiling (2011) (9)
ICGC PedBrain - dissecting the genomic complexity underlying medulloblastoma using whole-genome sequencing (2012) (8)
Autophosphorylation of the carboxyl‐terminal domain is not required for oncogenic transformation by lung‐cancer derived EGFR mutants (2018) (8)
Pugh et al. reply (2015) (8)
Telomerase as a therapeutic target in glioblastoma. (2021) (8)
Mechanistic insights into cancer cell killing through interaction of phosphodiesterase 3A and schlafen family member 12 (2020) (8)
Dissecting the clinicopathologic, genomic, and immunophenotypic correlates of KRASG12D mutated non-small cell lung cancer. (2022) (8)
Microarray approaches to gene expression analysis (2006) (7)
Erratum: Corrigendum: High-throughput oncogene mutation profiling in human cancer (2007) (7)
Erratum: Inferring loss-of-heterozygosity from unpaired tumors using high-density oligonucleotide SNP arrays (PLoS Computational Biology 2, 5, doi:10.1371/journal.pcbi.0020041) (2007) (7)
The Tangent copy-number inference pipeline for cancer genome analyses (2019) (7)
Erratum: High-throughput oncogene mutation profiling in human cancer (Nature Genetics (2007) 39, (347-351)) (2007) (7)
Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition (2020) (6)
Noncanonical junctions in subgenomic RNAs of SARS-CoV-2 lead to variant open reading frames (2020) (6)
Landscapes of childhood tumours (2018) (6)
Abstract 3302: The molecular landscape of oncogenic signaling pathways in The Cancer Genome Atlas (2018) (6)
Landscapes of childhood tumours. (2018) (6)
Identification and characterization of a novel activating mutation of the FLT3 tyrosine kinase in AML (2004) (5)
Abstract 4756: Exome sequencing of 81 neuroblastomas identifies a wide diversity of somatic mutation (2011) (5)
Abstract 3806: Progressive biallelic loss of TP53 is associated with progression of pleuropulmonary blastoma initiated by germline loss and somatic mutation of DICER1. (2013) (5)
Assessing prognosis in non-small-cell lung cancer: avenues to a more complete picture? (2004) (5)
Abstract 5455: Integrative analysis of the Cancer Cell Line Encyclopedia reveals genetic and transcriptional predictors of compound sensitivity (2011) (5)
Functional genomic analysis of CDK4 and CDK6 gene dependency across human cancer cell lines. (2022) (4)
The molecular landscape of oncogenic signaling pathways in The Cancer Genome Atlas (2018) (4)
Abstract 5060: Identification of somatic retrotransposon insertions across cancer types using RetroSeq (2012) (4)
Abstract 4286: Improved FFPE DNA extraction for next generation sequencing using adaptive focused acoustics technology (2014) (4)
Haplotype-resolved germline and somatic alterations in renal medullary carcinomas (2021) (4)
NSCLC Driven by DDR 2 Mutation Is Sensitive to Dasatinib and JQ 1 Combination Therapy (2015) (4)
Bacterial invaders drive CRC progression (2020) (3)
Comprehensive Bulk and Single Cell Transcriptomic Characterization of SF3B1 Mutation Reveals Its Pleiotropic Effects in Chronic Lymphocytic Leukemia (2015) (3)
Mutational processes shape the landscape of TP53 mutations in human cancer (2018) (3)
Abstract 3178: Can DNA from archived formalin-fixed paraffin embedded (FFPE) cancer tissues be used for somatic mutation analysis in next generation sequencing (2012) (3)
Long-read sequencing reveals complex patterns of wraparound transcription in polyomaviruses (2022) (3)
Adding pathogens by genomic subtraction (2008) (3)
Mechanistic Insights into Transmissible Cancers of Mammals. (2018) (3)
An international report on bacterial communities in esophageal squamous cell carcinoma (2021) (3)
Addendum: The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity (2018) (3)
EGFR kinase mutations in NSCLC: Unexpected structural and kinetic insights into the mechanism of the T790M resistance mutation and its inhibition by irreversible inhibitors including HKI-272 (2007) (3)
Breaking down RET breakpoints in lung adenocarcinoma. (2014) (3)
Precision medicine approach in kidney cancer: A pan renal cell carcinoma (RCC) study across three cancer genome atlas (TCGA) datasets for clinically relevant target identification. (2015) (2)
Abstract 1026: Oncogenic alterations in FGFR3 and ERBB2 lead to ligand-independent activation of PPARG in bladder cancer (2019) (2)
Characterization of Plasmacytoid Dendritic Cells, Microbial Sequences, and Identification of a Candidate Public T-Cell Clone in Kikuchi-Fujimoto Disease (2021) (2)
Tumor fraction in circulating free DNA as a biomarker of disease dynamics in metastatic prostate cancer. (2018) (2)
Gene Expression: MRNA Transcript Analysis (2003) (2)
Circulating Tumor DNA Provides a Sneak Peek into Treatment Responses in Non-Small Cell Lung Cancer. (2019) (2)
Abstract 3259: The genomic landscape of premalignant lung squamous cell carcinoma lesions (2017) (2)
SF3B1 Mutation Alters The Selection Of 3' RNA Splice Sites In Chronic Lymphocytic Leukemia (2013) (2)
Addendum: The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity (2012) (2)
Cancer Biology and Signal Transduction Acquired Resistance to Dasatinib in Lung Cancer Cell Lines Conferred by DDR 2 Gatekeeper Mutation and NF 1 Loss (2014) (2)
Genetic and transcriptional evolution alters cancer cell line drug response (2018) (2)
Abstract 1526: Integrative and comparative genomic analysis of East-Asian lung squamous cell carcinomas (2014) (2)
PD-156 The Massachusetts General Hospital/Dana-Farber Cancer Institute/Harvard Medical School Partners HealthCare Center for genetics and genomics experience with clinical testing for somatic EGFR mutations in NSCLC patients (2005) (2)
Inferring Loss-of-Heterozygosity From Tumor-only Samples Using High-Density Oligonucleotide SNP Arrays (2)
Somatic Genome Alterations in Human Lung Cancers (2014) (2)
Abstract 4868: Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations within a wide spectrum of genetic heterogeneity (2012) (2)
Abstract 993: Whole exome sequencing of CTCs as a window into metastatic cancer (2014) (2)
24 A NOVEL MOLECULAR CLASSIFICATION OF HCV-RELATED HEPATOCELLULAR CARCINOMA (HCC) BASED ON INTEGRATIVE GENOMIC ANALYSIS (2008) (2)
Whole genome sequencing reveals the independent clonal origin of multifocal ileal neuroendocrine tumors (2022) (2)
759 Diet and Risk of Colorectal Cancer According to Intratumoral Fusobacterium Nucleatum Levels (2016) (1)
A Candidate Cell-Selective Anticancer Agent (2014) (1)
Colon cancer-derived oncogenic EGFR G724S mutant identified by whole genome sequence analysis is dependent on asymmetric dimerization and sensitive to cetuximab (2014) (1)
Tumor genomic profiling of FFPE samples by massively parallel sequencing. (2011) (1)
virORF_direct - Pervasive generation of non-canonical subgenomic RNAs by SARS-CoV-2 (2020) (1)
Distinct MET alterations to induce a common phenotype and to define a MET-driven subset of papillary RCC: Results from the Cancer Genome Atlas (TCGA) Kidney Renal Papillary (KIRP) Working Group. (2015) (1)
Author Correction: Pan-cancer analysis of whole genomes (2023) (1)
Abstract 1682: Uncovering signals of somatic selection through whole exome and whole genome sequencing of lung adenocarcinoma (2012) (1)
Gene Expression: Protein Analysis (2003) (1)
Polymorphism Array Analysis Human Lung Carcinomas Revealed by Single Nucleotide Homozygous Deletions and Chromosome Amplifications in (2005) (1)
Pervasive generation of non-canonical subgenomic RNAs by SARS-CoV-2 (2020) (1)
Germline cancer susceptibility gene variants, somatic second hits, and survival outcomes in patients with resected pancreatic cancer (2018) (1)
Cancer Immunology at the Crossroads : Microbiology Microbes and In fl ammation in Colorectal Cancer (2013) (1)
Abstract 1112: Whole exome and whole genome sequence analysis of lung adenocarcinoma. (2013) (1)
Defining protein variant functions using high-complexity mutagenesis libraries and enhanced mutant detection software ASMv1.0 (2021) (1)
Whole-genome characterization of lung adenocarcinomas lacking alterations in the RTK/RAS/RAF pathway (2021) (1)
Therapeutics , Targets , and Chemical Biology Integrative Radiogenomic Pro fi ling of Squamous Cell Lung Cancer (2013) (1)
Discovery and Structure-Based Design of Potent Covalent PPARγ Inverse-Agonists BAY-4931 and BAY-0069. (2022) (1)
Abstract 5759: The landscape of copy-number changes across multiple human cancer types (2010) (1)
Crystal structures of EGFR in complex with Mig6 (2015) (1)
Abstract 4149: Transcriptomic and pathogen analysis in bladder cancer primary tumor and metastasis pairs. (2013) (1)
Abstract 4017: Dissecting the clonal hierarchy of cancer-driving genomic lesions. (2013) (1)
PD-145 Long-term survival of NSCLC patients with EGFR mutationstreated with EGFR TKIs gefitinib or erlotinib (2005) (1)
Genome-wide DNA methylation profiling of gastrointestinal neuroendocrine tumors to identify hypermethylation of mTOR, Wnt, and Notch pathways in GI NET pathogenesis (2014) (1)
Abstract 2976: Comprehensive Pan-Genomic characterization of adrenocortical carcinoma (2015) (1)
Pathogen discovery in AIDS-related lymphoma by high-throughput sequencing (2012) (1)
OMICS AND PROGNSTIC MARKERS (2013) (1)
Disruption of chromatin folding domains by somatic genomic rearrangements in human cancer (2020) (1)
Expressionof Sf3b1- K700Ein Murine B Cells Causes Pre-mRNA Splicing and Altered B Cell Differentiation and Function (2015) (1)
Abstract 3627: Validation of PPARG and RXRA as drivers of bladder cancer (2017) (1)
Analytical protocol to identify local ancestry-associated molecular features in cancer (2021) (1)
Abstract 1115: Targeted RNA sequencing improves transcript analysis in cancer samples (2015) (1)
Integrative analysis of the melanoma transcriptome Material Supplemental (2010) (1)
Tangent normalization for somatic copy-number inference in cancer genome analysis (2022) (1)
Large-Scale CLL Genome Analysis Reveals Novel Cancer Genes, Including SF3B1 (2011) (1)
Abstract 105: Integrative analysis of genomic and pharmacologic data from the Cancer Cell Line Encyclopedia (2010) (1)
Integrative Radiogenomic Profiling Identifies BRAF Mutations as Novel Radiotherapeutic Targets in Adenocarcinomas of the Lung (2014) (1)
Oncogenic ARAF as a new driver in lung adenocarcinoma. (2014) (1)
Abstract 4604: Landscape of human and viral genomic alterations in cervical carcinomas. (2013) (1)
A method for determining the responsiveness of a tumor to treatments with the epidermal growth factor receptor as a target (2005) (1)
Abstract 4872: ICGC PedBrain Tumor - Next-generation sequencing identifies novel subgroup-specific mutations and copy number aberrations in medulloblastoma (2012) (1)
Abstract 4867: Comparative analysis of RNA sequencing methods for characterization of cancer transcriptomics (2015) (1)
Abstract 1470: Preclinical activity of the first reversible, potent and selective inhibitor of EGFR exon 20 insertions (2021) (1)
Gefitinib resistance caused by a secondary mutation of the epidermal growth factor receptor (2005) (1)
Supplementary Material 10 (2014) (1)
Therapeutic targeting of extracellular FGFR2 activating deletions in intrahepatic cholangiocarcinoma. (2020) (1)
Genome-scale analysis identifies paralog lethality as a vulnerability of chromosome 1p loss in cancer (2018) (1)
Genetically-Defined Diffuse Large B-Cell Lymphoma Subsets Arise By Distinct Pathogenetic Mechanisms and Predict Outcome (2017) (1)
Analysis of germline-driven ancestry-associated gene expression in cancers (2022) (1)
Author Correction: Identification of ADAR1 adenosine deaminase dependency in a subset of cancer cells (2022) (1)
Abstract A177: Cetuximab resistance associated with dimerization‐independence of oncogenic EGFR mutants (2009) (1)
Abstract 1313: Mutually exclusive somatic mutations in WNT pathway medulloblastomas reveal a critical interaction between DDX3X and SMARCA4 (2012) (1)
Liron Bar-Peled GTPases That Signal Amino Acid Sufficiency to mTORC 1 A Tumor Suppressor Complex with GAP Activity for the Rag (2013) (1)
Publisher Correction: Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes (2018) (1)
Abstract 1574: The impact of human wild type EGFR on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies (2010) (1)
NRF2 Pathway Activation Regulates Radiation Resistance in Lung Squamous Cell Carcinoma (2012) (1)
Oncogenic ARAF as a New Driver in Lung Adenocarcinoma (2014) (1)
Abstract SY10-02: Pan-cancer study of recurrent and heterogeneous RNA aberrations and association with whole-genome variants (2017) (1)
Cdk6: Cyclin-dependent kinase-6 (vertebrates) (PLSTIIRE) (1995) (1)
Overview: Gene Structure (2003) (1)
Abstract 5129:Fusobacteriumand co-occurring microbes in primary and metastatic colorectal cancer (2018) (1)
Colon cancer-derived oncogenic EGFR G 724 S mutant (2014) (1)
Velcrin-induced selective cleavage of tRNALeu(TAA) by SLFN12 causes cancer cell death (2022) (1)
Abstract 5880: Small-molecule modulators of PDE3/SLFN12 to kill cancer cells (2018) (1)
Malignant Melanoma Modeling Genomic Diversity and Tumor Dependency in Updated (2008) (1)
Abstract SY25-03: Haploinsufficiency in cancer: When half simply isn't good enough. (2013) (0)
Abstract IA8: Genetic approaches to cancer (2012) (0)
Development of a High Throughput Platform for Measuring Radiation Response (2012) (0)
Abstract B13: FGFR2 as a therapeutic target in squamous cell lung carcinoma (2012) (0)
High-throughput oncogene mutation detection in human cancers by mass spectrometry-based genotyping (2006) (0)
Abstract 54: Cryo-EM structure of the PDE3A-SLFN12 complex reveals requirements for the activation of SLFN12 RNase and DNMDP-induced cancer cell killing (2021) (0)
Abstract 1097: FGFR2 in-frame indels: A novel targetable alteration in intrahepatic cholangiocarcinoma (2020) (0)
Molecular Profiling of Small Intestinal Neuroendocrine Tumours (SINETs) (2015) (0)
SNP array based analyses of somatic genetic and the identification of MITF as a lineage survival oncogene amplified in malignant melanoma (0)
Correction: Inferring Loss-of-Heterozygosity from Unpaired Tumors Using High-Density Oligonucleotide SNP Arrays (2007) (0)
Author Correction: Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes (2018) (0)
HER-2/neu expression is associated with increased tumor cell proliferation, loss of hormone receptors and an aggressive phenotype in a population based setting of endometrial carcinomas (2007) (0)
Abstract 5056: A glimpse into the somatic mutation landscape of melanoma through exome sequencing of 121 tumor-normal pairs (2012) (0)
Crystal structure of EGFR kinase domain G719S mutation in complex with AMP-PNP (2007) (0)
Scalable whole-exome sequencing of cell-free DNA reveals high concordance with metastatic tumors (2017) (0)
Functional Profiling of a Glioblastoma (GBM) Patient-Derived Cell Line (PDCL) Panel Identifies Cell-Intrinsic Differential Radiation Response That Correlates With TP53 Mutations (2015) (0)
Correction to: Oncogenic RIT1 mutations in lung adenocarcinoma (2022) (0)
amplification of C RKL ind uces t ra nsformation and epi dermal Growth Factor r ec eptor inh ibitor r es istance in hum an Non- s ma ll cel l lun g can cers (2011) (0)
Abstract LB-122: High-throughput tumor genomic profiling by massively parallel sequencing (2010) (0)
Genome Engineering to Generate Models of Chromosome Arm-Level Aneuploidies in Lung Cancer (2017) (0)
Genomic Evolution in a Patient With Lung Adenocarcinoma With a Germline EGFR T790M Mutation (2021) (0)
Abstract 2169: New telomeres and chromosomal arm fusions in cancer genomes revealed by long-read genome sequencing (2022) (0)
Abstract A36: Genome-scale ORF screening to identify modulators of the epithelial-to-mesenchymal transition (2017) (0)
Abstract 5020: A genome-scale ORF screen reveals an alternative splicing program that regulates mesenchymal and stem-like cell states in breast cancer (2017) (0)
Genomic landscape of high-grade T1 micropapillary bladder tumors. (2015) (0)
Abstract 1219: Deep mutational scanning of PDE3A identifies residues required for DNMDP response (2021) (0)
- Cdk5: Cyclin-dependent kinase 5 (vertebrates) (PSSALRE) (1995) (0)
Ultrasensitive detection of circulating LINE-1 ORF1p as a specific multi-cancer biomarker (2023) (0)
Publisher Correction: Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes (2018) (0)
Abstract HER2-05: HER2-05 Comprehensive genomic characterization of HER2-low breast cancer (2023) (0)
Abstract 3127: Integrated cistromic and expression analysis of amplified NKX2-1 in lung adenocarcinoma identifies LMO3 as a functional transcriptional target. (2013) (0)
target as a functional transcriptional LMO 3 lung adenocarcinoma identifies in NKX 2-1 Integrated cistromic and expression analysis of amplified Material Supplemental (2013) (0)
Abstract PD7-07: Somatic alterations in primary tumors of patients (pts) with metastatic breast cancer (MBC) may predict likelihood of brain metastasis (2023) (0)
Crystal structure of EGFR kinase domain T790M mutation in complex with AEE788 (2008) (0)
Abstract A2: Oncogenic and drug‐sensitiveERBB2mutations in glioblastoma (2009) (0)
Abstract 5895: Whole-genome characterization of lung adenocarcinomas lacking alterations in RTK/RAS/RAF/MAPK pathway (2020) (0)
Abstract 1501: Pan-cancer PathSeq analysis on TCGA data for pathogen discovery. (2013) (0)
Abstract IA-07: Genetic ancestry and lung cancer somatic mutations in patients of Latin American descent: Etiology and treatment implications (2022) (0)
CDKN1B SINET Ng.2821 (2013) (0)
Systematic Investigation of Genetic Vulnerabilities Across Cancer Cell Lines Reveals Lineage Specific Radiotherapeutic Determinants (2015) (0)
Abstract 6130: Cancer sensitivity to therapy is constrained by apoptosis regulation in cells of origin (2023) (0)
Abstract 6670: Combined signals from tumor and immune cells predict outcomes of checkpoint inhibition in melanoma (2020) (0)
High Throughput Sequencing-Based Pathogen Discovery In Multiple Myeloma (2013) (0)
Abstract PR07: Towards precision functional genomics via next-generation functional mapping of cancer variants (2015) (0)
Crystal structure of EGFR kinase domain L858R mutation in complex with AMP-PNP (2007) (0)
Abstract 3804: Rare DNA variants are enriched at the BARD1 locus and likely influence neuroblastoma susceptibility. (2013) (0)
Molecular portraits of lung cancer evolution (2023) (0)
Abstract 2131: Accurate quantitation of absolute allelic copy-numbers in primary solid tumor samples from SNP-array / WGS data reveals patterns of tumor progression (2010) (0)
IBS05.02 Functional Genomic Approaches to Identify Novel Therapeutic Targets in Lung Cancer (2019) (0)
Crystal structure of EGFR kinase domain T790M mutation (2008) (0)
Abstract 4596: An integrated genomic characterization of the target of a small molecule identifies a novel cancer dependency (2014) (0)
Abstract PR08:NF1,MET, andRIT1mutations are RAS-pathway driver events in lung adenocarcinoma (2014) (0)
Genomic basis for RNA alterations in cancer (2020) (0)
Abstract A23: An integrated platform for the functional annotation of the cancer genome (2009) (0)
Abstract PR05: Genome-scale CRISPR-Cas9 screening to identify essential genes and pathways in pancreatic cancer (2016) (0)
Abstract A003: Enhancer amplification defines lineage addiction in human lung adenocarcinoma (2022) (0)
Abstract B130: The intratumoral heterogeneity of glioblastoma suggests a pivotal role for clonal evolution. (2013) (0)
Abstract 819: Targeted sequencing to detect somatic mutations, translocations and copy-number variation in human tumors simultaneously. (2013) (0)
Abstract B2-21: Identification of somatic RNA splicing alterations in human cancers (2015) (0)
Abstract 895: Genomic characterization of premalignant lung squamous cell carcinoma lesions (2016) (0)
Abstract 2663: Preclinical profiling of BAY 2666605: The first PDE3A-SLFN12 complex inducer for cancer therapy (2022) (0)
EML4-ALK fusion gene and sensitivity to an ALK kinase inhibitor in lung cancer (2008) (0)
Abstract 4263: Identifying somatic mutation hotspots across protein family alignments (2014) (0)
Abstract 4600: Analysis of clonal evolution in cancer using whole exome sequence data reveals that subclonal driver mutations predict poor prognosis in chronic lymphocytic leukemia. (2013) (0)
Abstract 2966: Amplification and activation ofGATA6sustain oncogenic lineage-survival in esophageal adenocarcinoma (2012) (0)
Abstract B39: Genomic copy number alterations introduce a gene-independent viability bias in CRISPR-Cas9 knock-out screens of cancer cell lines (2017) (0)
Abstract SY11-02: Long-read sequencing reveals complex patterns of wraparound transcription in polyomaviruses (2022) (0)
Gene Analysis: DNA (2003) (0)
High-throughput genomic analysis of small-cell lung cancer: allelotyping using Affymetrix HuSNP arrays (2001) (0)
Abstract C139: Oncogenic ARAF mutation in a metastatic lung adenocarcinoma from a patient exhibiting sustained sorafenib response. (2013) (0)
Genome-wide copy number analysis of cell-free DNA from patients with chemotherapy-resistant metastatic triple-negative breast cancer. (2017) (0)
MA 12.06 Using Population Dynamics Mathematical Modeling to Optimize an Intermittent Dosing Regimen for Osimertinib in EGFR-Mutant NSCLC (2017) (0)
Crystal structure of EGFR kinase domain in complex with AEE788 (2007) (0)
Author Correction: Inferring structural variant cancer cell fraction (2022) (0)
Abstract PR02: Recurrent oncogenic mutations in the small GTPase RIT1 activate PI3K and MEK. (2014) (0)
Abstract 984: Alteration of the p53 pathway is associated with subclonal tumor progression in glioblastoma (2014) (0)
Abstract 3248: Genomic characterization of premalignant lung squamous cell carcinoma lesions (2018) (0)
Abstract 1139: Complete characterization of prostate cancer genomes by massively parallel sequencing (2010) (0)
Abstract A73: BCL-XL dependency in a subset of ovarian clear-cell carcinoma cell lines (2020) (0)
Abstract 957: Towards precision functional genomics via next-generation functional mapping of cancer variants (2015) (0)
Molecular origins of lung cancer - prospects for personalized prevention and therapy. Proceedings and abstracts of a meeting. January 10-14, 2010. San Diego, California, USA. (2010) (0)
Abstract 4259: The radiogenomic landscape of cancer (2014) (0)
Corrigendum: Recurrent hormone-binding domain truncated ESR1 amplifications in primary endometrial cancers suggest their implication in hormone independent growth (2016) (0)
Transcriptional and Functional Activity of Canine Hemangiosarcoma to Support Hematopoiesis Demonstrate Bone Marrow Nurse Cell Ontogeny (2021) (0)
Abstract IA7: Somatic genome alterations in human lung cancers (2012) (0)
Epidermal growth factor receptor (EGFR) mutation testing in non-small cell lung cancer (NSCLC) patients (pts). (2016) (0)
Abstract PR01:Fusobacterium nucleatumand mutational landscape of colorectal cancer in whole-exome sequencing analysis (2017) (0)
BAY 2927088: The first non-covalent, potent, and selective tyrosine kinase inhibitor targeting EGFR exon 20 insertions and C797S resistance mutations in NSCLC (2022) (0)
1314 RECURRENT MUTATIONS IN SPOP DEFINE A DISTINCT MOLECULAR CLASS OF PROSTATE CANCER (2012) (0)
Sporadic hemangioblastomas are characterized by cryptic VHL inactivation (2014) (0)
MA 06.14 Oncogenic SOS1 Mutations in Lung Adenocarcinoma (2017) (0)
Abstract LB-225: Liquid biopsies identify trunk mutations and reflect multiple tumors in a patient (2018) (0)
C7-06: Translational lung cancer genomics (2007) (0)
Telomerase inhibition is an effective therapeutic strategy in TERT promoter mutant-glioblastoma models with low tumor volume. (2023) (0)
Integrated genomic characterization of oesophageal carcinoma (2017) (0)
Patterns of structural variation define prostate cancer across disease states (2022) (0)
Abstract 3886: Comparing the mutational landscape of African American and Caucasian lung cancers (2015) (0)
Abstract A22: Identifying somatic mutation hotspots across protein family alignments. (2013) (0)
MODULATING DSRNA EDITING, SENSING, AND METABOLISM TO INCREASE TUMOR IMMUNITY AND IMPROVE THE EFFICACY OF CANCER IMMUNOTHERAPY AND/OR MODULATORS OF INTRATUMORAL INTERFERON (2018) (0)
Abstract 62: Inhibition ofMen1-deficient tumor growth by inactivation of the Rbp2 histone demethylase (2011) (0)
Abstract PR4: Integrative analysis of genomic and pharmacologic data from the Cancer Cell Line Encyclopedia (2010) (0)
TITLE: Sensitive detection of minimal residual disease in patients treated for early- 1 stage breast cancer 2 (2020) (0)
Abstract 4972: High-throughput functional profiling of dedifferentiated liposarcoma cell lines (2011) (0)
Abstract 4035: Preclinical activity of BAY 2927088 in HER2 mutant non-small cell lung cancer (2023) (0)
Abstract 46: Independent clonal origins of synchronous primary tumors in multifocal ileal neuroendocrine tumor patients (2022) (0)
Molecular Biology, Genomics, and Proteomics (2003) (0)
Abstract 3301: Breast cancer subtypes have distinct microbial and immune cytolytic transcriptomic signatures (2016) (0)
Table 1, Summary of Probe Properties from PubChem* (2014) (0)
Abstract 2135: Functional models of chromosome arm aneuploidies in lung squamous cell carcinoma (2021) (0)
Abstract C140: RIT1 mutations define a new genetic subset of lung adenocarcinoma. (2013) (0)
Correction: Functional Genomic Analysis of CDK4 and CDK6 Gene Dependency across Human Cancer Cell Lines. (2022) (0)
Author Correction: Identification of ADAR1 adenosine deaminase dependency in a subset of cancer cells (2018) (0)
Inferring Loss-of-Heterozygosity from Tumors Without Paired Normals Using High-Density SNP Arrays (2005) (0)
Oncogenic RIT1 mutations in lung adenocarcinoma this article openly available. Please share how this access benefits you. Your story matters (2014) (0)
Author Correction: Patterns of somatic structural variation in human cancer genomes (2020) (0)
Abstract PR12: High-throughput gene expression profiling as a generalizable assay for determination of mutation impact on gene function (2015) (0)
Abstract 2028: PDE3A modulation for cancer therapy (2017) (0)
Abstract 963: Characterizing acquired resistance mechanisms to targeted therapy in FGFR1-amplified lung squamous cell carcinoma. (2013) (0)
Author Correction: Patterns of somatic structural variation in human cancer genomes (2020) (0)
HEMATOPOIESIS AND STEM CELLS Distinct pathways regulated by menin and by MLL 1 in hematopoietic stem cells and developing B cells (2013) (0)
P2.03b-042 MET exon 14 Mutations Encode a Hyperactive Kinase and Therapeutic Target in Lung Adenocarcinoma (2017) (0)
The Radiogenomic Landscape of Cancer (2014) (0)
Method for determining the response of cancer to treatments directed at the epidermal growth factor receptor (2005) (0)
Abstract PR1: Integrating expression data improves mutational significance analysis of lung squamous carcinoma (2012) (0)
Abstract P5-14-06: Tumor Genomic Landscape in Older Women with Metastatic Breast Cancer (MBC) (2023) (0)
Abstract 3021: Mechanistic insight into MIG6 phosphorylation-mediated inhibitory effect on active EGFR. (2013) (0)
Somatic genomic alterations in urothelial cancer: Results of the Cancer Genome Atlas (TCGA) bladder cancer (BC) analysis. (2014) (0)
Sequence-Based Discovery of Novel Bacteria, Bradyrhizobium Enterica, in Cord Colitis Syndrome (2013) (0)
Identifying and correcting repeat-calling errors in nanopore sequencing of telomeres (2022) (0)
Corrigendum: Recurrent hormone-binding domain truncated ESR1 amplifications in primary endometrial cancers suggest their implication in hormone independent growth (2017) (0)
Crystal structure of EGFR kinase domain in complex with AMP-PNP (2007) (0)
CirculatingTumorDNAProvidesaSneakPeek into Treatment Responses in Non–Small Cell Lung Cancer (2019) (0)
From Human Genetic to Mouse Model: SF3B1 Mutation and its Impact on Chronic Lymphocytic Leukemia (2016) (0)
Author Correction: Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples (2020) (0)
Abstract 5135: Analysis of formalin-fixed paraffin-embedded (FFPE) samples. (2013) (0)
Abstract 4601: Punctuated evolution of prostate cancer genomes. (2013) (0)
Abstract 5321: BreaKmer: Detection of structural rearrangements in targeted next-generation sequencing data using kmers (2014) (0)
Proliferative Potential Recurrent Hemizygous Deletions in Cancers May Optimize (2012) (0)
Supplemental Information Transcriptomic Characterization of SF 3 B 1 Mutation Reveals Its Pleiotropic Effects in Chronic Lymphocytic Leukemia (2016) (0)
Abstract 15: Suppression of adaptive responses to targeted therapies by transcriptional inhibition (2017) (0)
Abstract 4760: Molecular classification and risk-stratification in medulloblastoma using an integrative genomic approach (2011) (0)
P3.02-086 MGA Suppresses the MYC Pathway in Lung Adenocarcinoma (2017) (0)
Abstract ED01-01: Somatic alterations in human cancer genomes. (2013) (0)
Targeted genomic rearrangements using CRISPR/Cas technology Please share how this access benefits you. Your story matters (2014) (0)
EXTH-11. TELOMERASE INHIBITION IS AN EFFECTIVE THERAPEUTIC STRATEGY IN TERT PROMOTER-MUTANT GLIOBLASTOMAS MODELS WITH LOW TUMOR BURDEN (2022) (0)
Abstract 409: Genome engineering to generate models of chromosome arm-level aneuploidies in lung carcinoma (2017) (0)
Abstract A199: Oncogenic and drug‐sensitive ERBB2 mutations in glioblastoma (2009) (0)
Correction: Profiling Critical Cancer Gene Mutations in Clinical Tumor Samples (2009) (0)
Abstract LB-146: Identification of copy number alterations in small cell lung cancer (2010) (0)
Abstract 3583: Reducing GC-bias and improving coverage distribution in Illumina sequencing using the Kapa Biosystems library construction method (2014) (0)
Abstract A44: Functional models of chromosome arm-level aneuploidies in cancer (2020) (0)
Mutants Is Associated with Asymmetric Dimerization Derived EGF Receptor − Cetuximab Response of Lung Cancer (2013) (0)
am plification of CRKL in duces t r ansformation and ep idermal Growth Factor r e ceptor in hibitor r e sistance in hu man Non- s m all ce ll lu ng ca ncers (2011) (0)
Abstract PR04: High-throughput gene expression profiling as a generalizable assay for determination of mutation impact on gene function (2015) (0)
Deciphering, simulating and editing of the cancer genome : extended abstracts for the 49th International Symposium of the Princess Takamatsu Cancer Research Fund : November 6-8, 2018 Tokyo, Japan (2019) (0)
Role o f T elomerase i n N ormal a nd C ancer C ells (2000) (0)
NRF2 Is a Novel Oncogene and Biomarker of Therapeutic Resistance in Non-Small Cell Lung Cancer : Novel Therapies/Experimental Therapies (2014) (0)
Next-Generation Sequencing for the Identification of Transplantation-Associated Pathogens (2012) (0)
NRF2 Is a Novel Oncogene and Biomarker of Therapeutic Resistance in Non-Small Cell Lung Cancer (2014) (0)
Abstract PL03-02: Somatic mutations, germline risk and ancestry in lung adenocarcinoma (2022) (0)
Abstract 669: Compound heterozygous Sf3b1-K700E mutation and Atm deletion in B cells leads to CLL in mice (2016) (0)
Author Correction: Genomic basis for RNA alterations in cancer (2023) (0)
Abstract 2151: Identification and proteogenomic characterization of novel lung adenocarcinoma subtypes with therapeutic relevance (2022) (0)
Correction: Profiling Critical Cancer Gene Mutations in Clinical Tumor Samples (2009) (0)
Abstract 3965: An algorithm to detect somatic mutations in cancer specimens using mass spectrometric genotyping (2012) (0)
Abstract 867: Velcrin-induced cleavage of tRNA-Leu-TAA by SLFN12 RNase causes cancer cell death (2022) (0)
Abstract 949: PathSeq: A comprehensive computational tool for pathogen discovery by deep sequencing of human cancer tissues (2011) (0)
Abstract ND04: BAY 2666605: The first PDE3A-SLFN12 complex inducer for cancer therapy (2022) (0)
Abstract 214: Genetic and transcriptional instability alters cell line drug response (2018) (0)
Abstract IA2: Somatic alterations in human cancer genomes (2013) (0)
Study of genetic alterations in soft tissue sarcomas by SNP arrays, expression profiling and high-throughput sequencing (2007) (0)
Abstract PL07-01: Molecular profiling of breast cancer in Mexico: Identification of novel therapeutic targets through whole genome sequencing analysis. (2012) (0)
Functional Analysis of Somatic Mutations in Lung Cancer (2015) (0)
Abstract 3002: Genome engineering approaches to generate models of chromosome arm-level cancer aneuploidy (2018) (0)
Abstract 4692: Relationships between somatic genomic alterations, tumor stage and progression-free survival in cervical cancer (2014) (0)
Haplotype-resolved germline and somatic alterations in renal medullary carcinomas (2021) (0)
Oncogenesis and Colon Exhibit Distinct Patterns of Genome Instability and Gastrointestinal Adenocarcinomas of the Esophagus, Stomach, (2012) (0)
Whole‐exome sequencing analyses of colorectal cancer with Fusobacterium nucleatum (2017) (0)
Abstract 3644: Optimization of library construction for massively parallel sequencing using low-input, FFPE-derived DNA without additional PCR amplification (2016) (0)
Abstract 197: A systemic model derivation platform for generating 3D neuroendocrine tumor cell spheroids to accelerate cancer research (2022) (0)
Abstract 4616: Exploring the role of interferon and innate immune regulators in outlier cancer cell line survival (2017) (0)
Correction: Mechanistic insights into cancer cell killing through interaction of phosphodiesterase 3A and schlafen family member 12. (2020) (0)
Somatic Genome Changes in Human Non–Small Cell Lung Cancers (2017) (0)
Abstract C136: Identification of selective cancer cytotoxic modulators of phosphodiesterase 3a by predictive chemogenomics (2015) (0)
EXTH-61. RPP25L IS A NOVEL DEPENDENCY IN GLIOBLASTOMAS WITH LOW RPP25 EXPRESSION (2022) (0)
Whole genome sequencing reveals the independent clonal origin of multifocal ileal neuroendocrine tumors (2022) (0)
Cancer Growth Factor Receptor ( EGFR ) Exon 20 Insertion Mutations in Lung Structural , Biochemical , and Clinical Characterization of Epidermal (2013) (0)
Correction to “Discovery and Structure-Based Design of Potent Covalent PPARγ Inverse-Agonists BAY-4931 and BAY-0069” (2022) (0)
Abstract 4583: An essential role for Cmtr2 in endothelial cell function and vascular development (2023) (0)
Crystal structure of EGFR kinase domain in complex with Iressa (2007) (0)
hypermutability with distinct patterns of DNA breakage and rearrangement-induced Somatic rearrangements across cancer reveal classes of samples Material Supplemental (2013) (0)
Supplementary Material 8 (2013) (0)
Abstract B06: Investigating the microbial etiology of Tanzanian esophageal squamous cell carcinoma (2020) (0)
Erratum to “Pathogen discovery from human tissue by sequence-based computational subtraction” ☆: [Genomics 81 (2003) 329–335]☆ (2003) (0)
Abstract 3890: Sequencing of 888 pediatric solid tumors informs precision oncology trial design and data sharing initiatives in pediatric cancer (2022) (0)
TP63 Fusions Drive Enhancer Rewiring, Lymphomagenesis, and Dependence on EZH2 (2022) (0)
Somatic genome alterations in triple‐negative breast cancer (2013) (0)
In search of human proteins and infectious triggers involved in periodic fever, aphthous stomatitis, pharyngitis and adenitis syndrome (2015) (0)
Pathogen discovery in AIDS-related lymphoma by high-throughput sequencing (2012) (0)
Arrays the Cancer Genome Using Single Nucleotide Polymorphism An Integrated View of Copy Number and Allelic Alterations in Updated (2004) (0)
Fusobacterium and Colorectal Cancer: Important Association or Random Coincidence? (2022) (0)
Functional profiling of a glioblastoma (GBM) patient-derived cell line (PDCL) panel to identify cell-intrinsic differential radiation response. (2016) (0)
Abstract 3315: Functional genomic profiling of lung adenocarcinoma identifies BRAF mutations as novel therapeutic targets (2015) (0)
1133OMOLECULAR PROFILING OF SMALL INTESTINAL NEUROENDOCRINE TUMOURS. (2014) (0)
The catalytic subunit of yeast telomerase ( telomeres y reverse transcriptase (1997) (0)
IS-10-1 Genomic alterations in human cancer(IS-10 Treatment of lung cancer in the 21st century : From bench to bedside, further to the OR) (2011) (0)
Author Correction: The evolutionary history of 2,658 cancers (2023) (0)
Abstract 4727: Genomic characterization of brain metastases reveals divergent evolution and metastasis specific mutations (2015) (0)
FLT3 Tyrosine Kinase in AML Identification and Characterization of a Novel Activating Mutation of the (2012) (0)
Abstract 879: SLFN12-mediated depletion of tRNA-Leu-TAA by velcrin treatment induces ribosome pausing at Leu-TTA codons and represses global translation initiation (2022) (0)
Abstract B39: Nkx2-1 down-regulation underlies lung adenocarcinoma progression towards malignancy (2009) (0)
33 Approaches to inhibit the Akt pathway (2004) (0)
THE P53 PATHWAY AND ANCESTRAL PROGENITORS ARE ASSOCIATED WITH TUMOR RECURRENCE IN GLIOBLASTOMA (2014) (0)
Abstract 3150: Characterizing the effects of somatic mutations in splice factors on the transcriptome. (2013) (0)
Cdk3: Cyclin-dependent kinase-3 (vertebrates) (1995) (0)
C6-07: Mutations in the LKB1 tumor suppressor are frequently found in tumors from Caucasian NSCLC patients (2007) (0)
Abstract 5695: Increased sensitivity for detection of oncogenic mutations present in circulating cell-free tumor DNA (2017) (0)
Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes (2018) (0)
Abstract 2620: The Cancer Cell Line Encyclopedia project: From integrative cancer genomics to personalized cancer therapy (2010) (0)
Discovery and characterization of orally bioavailable 4-chloro-6-fluoroisophthalamides as covalent PPARG inverse-agonists. (2022) (0)
Abstract 1391: SOX2-p63 interaction and genomic co-localization in squamous cell carcinomas (2014) (0)
Promoter Hypermethylation at RASSF1 is a Feature of Small Intestinal Neuroendocrine Tumors (2014) (0)
Abstract AP14: POOLED GENOMIC SCREENS IDENTIFY ANTI-APOPTOTIC GENES AS MEDIATORS OF CHEMOTHERAPY RESISTANCE IN OVARIAN CANCER (2019) (0)
Abstract 5668: Genomic correlates ofPD-L1expression are associated with response to immunotherapy in non-small cell lung cancer (2020) (0)
On behalf of the IEEE Communications Society and the IEEE GLOBECOM 2010 Executive Committee, we are pleased to welcome you to the 53rd IEEE Global Communications Conference (IEEE GLOBECOM) in beautiful Miami. (2010) (0)
Massively parallel sequencing of formalin-fixed paraffin-embedded tissues (2012) (0)
Dooley 1 Nuclear Factor I / B is an Oncogene in Small Cell Lung Cancer (2011) (0)
The Transcriptome Architecture of Polyomaviruses (2021) (0)
Unique, dual-indexed sequencing adapters with UMIs effectively eliminate index cross-talk and significantly improve sensitivity of massively parallel sequencing (2018) (0)
Translational lung cancer genomics (2007) (0)
A Functional Landscape o f Resistance to ALK Inhibition in Lung Cancer Graphical Abstract Highlights (2015) (0)
Abstract 4018: Whole exome sequencing analysis of familial Medulloblastoma. (2013) (0)
hi gh-t h roughput Detection of ac tionable Genomic al terations in cl inical t u mor s a mples by t a rgeted, Massively Parallel s e quencing (2012) (0)
Bifidobacterium Genus in Colorectal Carcinoma Tissue in relation to Tumor Characteristics and Patient Survival (2018) (0)
P2. In search of a candidate pathogen for GCA: sequencing based characterization of the GCA microbiome (2014) (0)
Delineation of inhibitor-sensitive/resistant transforming mutations by mutagenesis of EGFR (2006) (0)
Crystal structure of EGFR kinase domain T790M mutation in compex with HKI-272 (2008) (0)
The Characterization of the Interaction Between Phosphodiesterase 3A and Compound 1B, a Novel Selective Cytotoxic Agent (2014) (0)
Abstract P5-01-03: Ultrasensitive detection of minimal residual disease in patients treated for breast cancer (2020) (0)
Abstract 5752: Enhancer amplification defines lineage addiction in human lung adenocarcinoma (2023) (0)
Molecular Biology, Genomics, Proteomics, and Mouse Models of Human Cancer (2017) (0)
CBMT-21. TERT PROMOTER-MUTANT GLIOBLASTOMAS EXHIBIT DEPENDENCY ON TELOMERASE (2019) (0)
DNA copy number analysis of metastatic urothelial carcinoma with comparison to primary tumors (2015) (0)
GE-17ALTERATION OF THE p53 PATHWAY AND ANCESTRAL PROGENITORS ARE ASSOCIATED WITH TUMOR RECURRENCE IN GLIOBLASTOMA (2014) (0)
Abstract LB-136: High concordance of whole-exome sequencing of cell-free DNA and matched biopsies enables genomic discovery in metastatic cancer (2016) (0)
Selective and mechanistic pressures shaping cancer aneuploidies (2021) (0)
Abstract 562: Oncovirus detection and integration analysis from human tumor samples using targeted massively parallel sequencing (2017) (0)
Abstract 3925: Characterization of complex chromosomal aberrations in prostate cancer from whole genome sequencing (2011) (0)
Comprehensivemolecularcharacterization of human colon and rectal cancer (2012) (0)
Crystal structure of EGFR kinase domain in complex with AFN941 (2007) (0)
Bacillus Cereus: A Leukemia-Specific, Neuroinvasive Pathogen? (2014) (0)
Abstract 4560: Fusobacterium nucleatum and tumor immunity status according to microsatellite instability in colorectal cancer (2017) (0)

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