Matthias Heinemann
#160,120
Most Influential Person Now
Professor of molecular systems biology
Matthias Heinemann's AcademicInfluence.com Rankings
Matthias Heinemannbiology Degrees
Biology
#13957
World Rank
#17582
Historical Rank
Systems Biology
#39
World Rank
#39
Historical Rank
Molecular Biology
#2581
World Rank
#2622
Historical Rank
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Biology
Matthias Heinemann's Degrees
- PhD Molecular Biology University of Groningen
- Masters Biotechnology University of Groningen
- Bachelors Biotechnology University of Groningen
Why Is Matthias Heinemann Influential?
(Suggest an Edit or Addition)According to Wikipedia, Matthias Heinemann is a professor of molecular systems biology at the University of Groningen. Heinemann leads an interdisciplinary lab of approximately 12 graduate students and post-doctoral scholars. Until 2019, he served as the chairman of the Groningen Biomolecular Sciences and Biotechnology Institute, was a board member of the Dutch Origins Center and the coordinator of EU ITN project MetaRNA. Heinemann is a member of the Faculty of 1000.
Matthias Heinemann's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A consensus yeast metabolic network reconstruction obtained from a community approach to systems biology (2008) (601)
- Definitions and guidelines for research on antibiotic persistence (2019) (575)
- The quantitative and condition-dependent Escherichia coli proteome (2015) (546)
- Multidimensional Optimality of Microbial Metabolism (2012) (394)
- Synthetic biology - putting engineering into biology (2006) (352)
- Condition-Dependent Cell Volume and Concentration of Escherichia coli to Facilitate Data Conversion for Systems Biology Modeling (2011) (310)
- Putative regulatory sites unraveled by network-embedded thermodynamic analysis of metabolome data (2006) (287)
- Getting Closer to the Whole Picture (2007) (285)
- From good old biochemical analyses to high-throughput omics measurements and back. (2011) (255)
- Bacterial adaptation through distributed sensing of metabolic fluxes (2010) (242)
- Phenotypic bistability in Escherichia coli's central carbon metabolism (2014) (219)
- Whole lifespan microscopic observation of budding yeast aging through a microfluidic dissection platform (2012) (206)
- The Cost of Virulence: Retarded Growth of Salmonella Typhimurium Cells Expressing Type III Secretion System 1 (2011) (203)
- Mass spectrometry-based metabolomics of single yeast cells (2013) (190)
- Mass spectrometry-based metabolomics: a guide for annotation, quantification and best reporting practices (2021) (186)
- Functioning of a metabolic flux sensor in Escherichia coli (2012) (186)
- Systematic assignment of thermodynamic constraints in metabolic network models (2006) (161)
- Protein biogenesis machinery is a driver of replicative aging in yeast (2015) (150)
- Bacterial persistence is an active σS stress response to metabolic flux limitation (2016) (143)
- In silico genome-scale reconstruction and validation of the Staphylococcus aureus metabolic network. (2005) (140)
- Prediction of Microbial Growth Rate versus Biomass Yield by a Metabolic Network with Kinetic Parameters (2012) (136)
- Systems biology of microbial metabolism. (2010) (128)
- Single cell metabolomics. (2011) (125)
- Optimization of a blueprint for in vitro glycolysis by metabolic real-time analysis. (2011) (123)
- Dissecting specific and global transcriptional regulation of bacterial gene expression (2013) (121)
- Mass spectrometric method for analyzing metabolites in yeast with single cell sensitivity. (2008) (119)
- Autonomous Metabolic Oscillations Robustly Gate the Early and Late Cell Cycle. (2017) (118)
- Comprehensive quantitative analysis of central carbon and amino-acid metabolism in Saccharomyces cerevisiae under multiple conditions by targeted proteomics (2011) (116)
- Temporal system-level organization of the switch from glycolytic to gluconeogenic operation in yeast (2013) (110)
- An upper limit on Gibbs energy dissipation governs cellular metabolism (2019) (94)
- Physiology of mycobacteria. (2009) (93)
- A flux-sensing mechanism could regulate the switch between respiration and fermentation. (2012) (90)
- Nutritional Systems Biology Modeling: From Molecular Mechanisms to Physiology (2009) (87)
- Reporter Metabolite Analysis of Transcriptional Profiles of a Staphylococcus aureus Strain with Normal Phenotype and Its Isogenic hemB Mutant Displaying the Small-Colony-Variant Phenotype (2006) (86)
- Exploiting cell‐free systems: Implementation and debugging of a system of biotransformations (2010) (86)
- anNET: a tool for network-embedded thermodynamic analysis of quantitative metabolome data (2008) (84)
- RNA polymerase III limits longevity downstream of TORC1 (2017) (75)
- How bacteria recognise and respond to surface contact (2019) (73)
- Metabolic heterogeneity in clonal microbial populations. (2018) (70)
- System-Level Insights into Yeast Metabolism by Thermodynamic Analysis of Elementary Flux Modes (2012) (69)
- Integrated operation of continuous chromatography and biotransformations for the generic high yield production of fine chemicals. (2006) (63)
- Differential glucose repression in common yeast strains in response to HXK2 deletion. (2010) (62)
- Publisher Correction: Definitions and guidelines for research on antibiotic persistence (2019) (53)
- Optimization of adsorptive immobilization of alcohol dehydrogenases. (2005) (43)
- Bacterial persistence from a system-level perspective. (2017) (42)
- Metabolic-flux dependent regulation of microbial physiology. (2018) (42)
- Calorie restriction does not elicit a robust extension of replicative lifespan in Saccharomyces cerevisiae (2014) (41)
- Differential scaling between G1 protein production and cell size dynamics promotes commitment to the cell division cycle in budding yeast (2019) (41)
- Living with an imperfect cell wall: compensation of femAB inactivation in Staphylococcus aureus (2007) (38)
- Construction and use of a microfluidic dissection platform for long-term imaging of cellular processes in budding yeast (2013) (38)
- An engineered Calvin-Benson-Bassham cycle for carbon dioxide fixation in Methylobacterium extorquens AM1. (2018) (37)
- Optimization of Enzymatic Gas‐Phase Reactions by Increasing the Long‐Term Stability of the Catalyst (2004) (36)
- Thermodynamic calculations for biochemical transport and reaction processes in metabolic networks. (2010) (35)
- A divide-and-conquer approach to analyze underdetermined biochemical models (2009) (35)
- Physical bioenergetics: Energy fluxes, budgets, and constraints in cells (2021) (32)
- Carbon-13 labelling strategy for studying the ATP metabolism in individual yeast cells by micro-arrays for mass spectrometry. (2011) (32)
- Quantitative characterization of the auxin-inducible degron: a guide for dynamic protein depletion in single yeast cells (2017) (32)
- A new approach for the spatially resolved qualitative analysis of the protein distribution in hydrogel beads based on confocal laser scanning microscopy (2002) (29)
- Saccharomyces cerevisiae goes through distinct metabolic phases during its replicative lifespan (2018) (26)
- Measuring glycolytic flux in single yeast cells with an orthogonal synthetic biosensor (2019) (26)
- Method for Quantitative Determination of Spatial Polymer Distribution in Alginate Beads Using Raman Spectroscopy (2005) (25)
- Dynamic single-cell NAD(P)H measurement reveals oscillatory metabolism throughout the E. coli cell division cycle (2018) (25)
- Enzymatic catalysis in gel-stabilized two-phase systems: improvement of the solvent phase (2002) (25)
- Assessment of the interaction between the flux‐signaling metabolite fructose‐1,6‐bisphosphate and the bacterial transcription factors CggR and Cra (2018) (23)
- Manipulating rod-shaped bacteria with optical tweezers (2019) (23)
- pH-optima in lipase-catalysed esterification (2005) (21)
- Characterization of the AlkS/PalkB‐expression system as an efficient tool for the production of recombinant proteins in Escherichia coli fed‐batch fermentations (2007) (21)
- Definitions and guidelines for research on antibiotic persistence (2019) (21)
- New insights in the spatially resolved dynamic pH measurement in macroscopic large absorbent particles by confocal laser scanning microscopy. (2004) (21)
- Distinct transcriptional regulation of the two Escherichia coli transhydrogenases PntAB and UdhA. (2016) (19)
- Bacillus subtilis biosensor engineered to assess meat spoilage. (2014) (18)
- Reassessing the role of the Escherichia coli CpxAR system in sensing surface contact (2018) (16)
- Experimental and Theoretical Analysis of Phase Equilibria in a Two-phase System Used for Biocatalytic Esterifications (2003) (15)
- Suitability of teicoplanin-aglycone bonded stationary phase for simulated moving bed enantioseparation of racemic amino acids employing composition-constrained eluents. (2006) (14)
- Inference of the High-Level Interaction Topology between the Metabolic and Cell-Cycle Oscillators from Single-Cell Dynamics. (2019) (13)
- Continuous high-resolution microscopic observation of replicative aging in budding yeast. (2013) (12)
- Mutations in respiratory complex I promote antibiotic persistence through alterations in intracellular acidity and protein synthesis (2022) (10)
- A synthetic RNA-based biosensor for fructose-1,6-bisphosphate that reports glycolytic flux. (2021) (9)
- Synthetic Biology: Putting Engineering into Bioengineering (2009) (7)
- Proceedings of the 16th European Symposium on Computer Aided Process Engineering and 9th International Symposium on Process Systems Engineering (2006) (7)
- A New Sugar for an Old Phage: a c-di-GMP-Dependent Polysaccharide Pathway Sensitizes Escherichia coli for Bacteriophage Infection (2021) (7)
- A synthetic RNA-based biosensor for fructose-1,6-bisphosphate that reports glycolytic flux (2020) (4)
- Unbiased metabolic flux inference through combined thermodynamic and 13C flux analysis (2020) (4)
- Transcriptional control of metabolic fluxes and computational identification of the governing principles (2010) (4)
- Implications of initial physiological conditions for bacterial adaptation to changing environments (2020) (4)
- A new sugar for an old phage: A c-di-GMP dependent polysaccharide pathway sensitizes E. coli for bacteriophage infection (2021) (3)
- Author response: Protein biogenesis machinery is a driver of replicative aging in yeast (2015) (3)
- A photo-switchable yeast isocitrate dehydrogenase to control metabolic flux through the citric acid cycle (2021) (3)
- Industrial multi-step biotransformations (2004) (3)
- The timing of Start is determined primarily by increased synthesis of the Cln3 activator rather than dilution of the Whi5 inhibitor (2022) (3)
- A CDK-independent metabolic oscillator orchestrates the budding yeast cell cycle (2017) (2)
- Temporal segregation of biosynthetic processes is responsible for metabolic oscillations during the budding yeast cell cycle (2023) (1)
- Faculty Opinions recommendation of Four key steps control glycolytic flux in mammalian cells. (2019) (1)
- Quantitative characterization of the auxin-inducible degron: a guide for dynamic protein depletion in single yeast cells (2017) (1)
- Metabolic dynamics during the cell cycle (2022) (1)
- A new approach for the production of DHAP (2005) (1)
- A robust method for generating, quantifying and testing large amounts of Escherichia coli persisters (2020) (1)
- Best practices for experimentation and reporting in 1 mass spectrometry based metabolomics 2 (2021) (0)
- University of Groningen Dynamic single-cell NAD ( P ) H measurement reveals oscillatory metabolism throughout the E . coli cell division cycle (2018) (0)
- Stochastic grey box modeling of the enzymatic biochemical reaction network of E. coli mutants (2006) (0)
- Label-free quantitative proteomics and a systematic analysis of Helicobacter pylori (2013) (0)
- Faculty of 1000 evaluation for Translational control of lipogenic enzymes in the cell cycle of synchronous, growing yeast cells. (2018) (0)
- University of Groningen Single cell metabolomics (2018) (0)
- Comparison of two sampling, quenching and extraction methods for quantitative yeasts metabolomics (2022) (0)
- Dynamic single-cell NAD(P)H measurement reveals oscillatory metabolism throughout the E. coli cell division cycle (2018) (0)
- Perspective: a stirring role for metabolism in cells (2022) (0)
- University of Groningen Prediction of Microbial Growth Rate versus Biomass Yield by a Metabolic Network with Kinetic Parameters Adadi, (2012) (0)
- How Bacteria Recognise and Respond to Surface Attachment (2019) (0)
- Faculty Opinions recommendation of TORC1 organized in inhibited domains (TOROIDs) regulate TORC1 activity. (2019) (0)
- Differential scaling between G1 protein production and cell size dynamics promotes commitment to the cell division cycle in budding yeast (2019) (0)
- Editorial overview: Systems biology for biotechnology. (2017) (0)
- Phenotype Displaying the Small-Colony-Variant Mutant hemB Phenotype and Its Isogenic Strain with Normal Staphylococcus aureus Transcriptional Profiles of a Reporter Metabolite Analysis of (2006) (0)
- Scanning electron microscopy pictures of cells adhering to Thermanox (2011) (0)
- Flux Controls Flux – a Key Challenge for Metabolic Engineering (2016) (0)
- Design of a system of biotransformations by means of stoichiometric network analysis (2005) (0)
- A Robust Method for Generating, Quantifying, and Testing Large Numbers of Escherichia coli Persisters. (2021) (0)
- Detailed survey of genome-wide expression differences between a Staphylococcus aureus mutant displaying the small colony variant phenotype and its parental strain (2006) (0)
- Faculty Opinions recommendation of Heat oscillations driven by the embryonic cell cycle reveal the energetic costs of signaling. (2019) (0)
- Model-based identification of regulation patterns controlling metabolic redundancy in central carbon metabolism (2005) (0)
- Mutations in respiratory complex I promote antibiotic persistence through alterations in intracellular acidity and protein synthesis (2022) (0)
- University of Groningen Method for Quantitative Determination of Spatial Polymer Distribution in Alginate Beads Using Raman Spectroscopy (2010) (0)
- Publisher Correction: Definitions and guidelines for research on antibiotic persistence (2019) (0)
- Model-Data Comparisons for Past Warm Climates: How Do We Know When We've Got It Right? (2007) (0)
- CDK and cAMP/PKA signalling tune the amplitude of the metabolic oscillator, thereby controlling cell cycle initiation or arrest (2017) (0)
- The Escherichia coli CpxAR system does not sense surface contact (2017) (0)
- Thermodynamic principles governing metabolic operation : inference , analysis , and prediction (2015) (0)
- An upper limit on Gibbs energy dissipation governs cellular metabolism (2019) (0)
- University of Groningen Mass Spectrometric Method for Analyzing Metabolites in Yeast with Single Cell Sensitivity Amantonico, (2008) (0)
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What Schools Are Affiliated With Matthias Heinemann?
Matthias Heinemann is affiliated with the following schools:
