Matthias Hentze
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German biologist
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Why Is Matthias Hentze Influential?
(Suggest an Edit or Addition)According to Wikipedia, Matthias Werner Hentze is a German scientist. He is the director of the European Molecular Biology Laboratory , co-director of the Molecular Medicine Partnership Unit between EMBL and Heidelberg University, and Professor of Molecular Medicine at Heidelberg University.
Matthias Hentze's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Insights into RNA Biology from an Atlas of Mammalian mRNA-Binding Proteins (2012) (1706)
- Two to Tango: Regulation of Mammalian Iron Metabolism (2010) (1683)
- Balancing Acts Molecular Control of Mammalian Iron Metabolism (2004) (1663)
- A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation. (2000) (1394)
- Molecular control of vertebrate iron metabolism: mRNA-based regulatory circuits operated by iron, nitric oxide, and oxidative stress. (1996) (1281)
- Molecular mechanisms of translational control (2004) (998)
- Hepcidin Regulates Cellular Iron Efflux by Binding to Ferroportin and Inducing Its Internalization (2004) (982)
- A brave new world of RNA-binding proteins (2018) (876)
- A Perfect Message RNA Surveillance and Nonsense-Mediated Decay (1999) (840)
- Starting at the Beginning, Middle, and End: Translation Initiation in Eukaryotes (1997) (693)
- A Red Carpet for Iron Metabolism (2017) (683)
- Iron-responsive elements: regulatory RNA sequences that control mRNA levels and translation. (1988) (604)
- Nonsense-mediated decay approaches the clinic (2004) (595)
- Systemic iron homeostasis and the iron-responsive element/iron-regulatory protein (IRE/IRP) regulatory network. (2008) (563)
- mRNA Silencing in Erythroid Differentiation: hnRNP K and hnRNP E1 Regulate 15-Lipoxygenase Translation from the 3′ End (1997) (527)
- STAT3 mediates hepatic hepcidin expression and its inflammatory stimulation. (2007) (526)
- Identification of the iron-responsive element for the translational regulation of human ferritin mRNA. (1987) (467)
- A sensitive array for microRNA expression profiling (miChip) based on locked nucleic acids (LNA). (2006) (444)
- Comprehensive Identification of RNA-Binding Domains in Human Cells (2016) (424)
- Iron regulates nitric oxide synthase activity by controlling nuclear transcription (1994) (417)
- Binary specification of nonsense codons by splicing and cytoplasmic translation (1998) (412)
- The RNA-binding protein repertoire of embryonic stem cells (2013) (410)
- Previously uncharacterized isoforms of divalent metal transporter (DMT)-1: Implications for regulation and cellular function (2002) (407)
- Circular RNAs: splicing's enigma variations (2013) (398)
- Translational regulation via iron‐responsive elements by the nitric oxide/NO‐synthase pathway. (1993) (369)
- Serum ferritin is derived primarily from macrophages through a nonclassical secretory pathway. (2010) (360)
- The RNA-binding proteomes from yeast to man harbour conserved enigmRBPs (2015) (347)
- Drosophila miR2 induces pseudo-polysomes and inhibits translation initiation (2007) (337)
- Rapid responses to oxidative stress mediated by iron regulatory protein. (1995) (331)
- Phosphorylation of hUPF1 induces formation of mRNA surveillance complexes containing hSMG-5 and hSMG-7. (2003) (324)
- The role of ABCE1 in eukaryotic posttermination ribosomal recycling. (2010) (323)
- Oxidation-reduction and the molecular mechanism of a regulatory RNA-protein interaction. (1989) (321)
- Interactions between UPF1, eRFs, PABP and the exon junction complex suggest an integrated model for mammalian NMD pathways (2008) (315)
- Iron‐dependent regulation of the divalent metal ion transporter (2001) (305)
- Exon-junction complex components specify distinct routes of nonsense-mediated mRNA decay with differential cofactor requirements. (2005) (303)
- Regulatory defects in liver and intestine implicate abnormal hepcidin and Cybrd1 expression in mouse hemochromatosis (2003) (301)
- ERK phosphorylation drives cytoplasmic accumulation of hnRNP-K and inhibition of mRNA translation (2001) (296)
- Y14 and hUpf3b form an NMD-activating complex. (2003) (287)
- Binding of a cytosolic protein to the iron-responsive element of human ferritin messenger RNA. (1988) (285)
- Dual function of the messenger RNA cap structure in poly(A)-tail-promoted translation in yeast (1998) (283)
- IRP-1 binding to ferritin mRNA prevents the recruitment of the small ribosomal subunit by the cap-binding complex eIF4F. (1998) (281)
- Lipoxygenase mRNA Silencing in Erythroid Differentiation The 3′UTR Regulatory Complex Controls 60S Ribosomal Subunit Joining (2001) (277)
- 3′ end mRNA processing: molecular mechanisms and implications for health and disease (2008) (274)
- Iron-regulatory proteins limit hypoxia-inducible factor-2α expression in iron deficiency (2007) (273)
- Increased efficiency of mRNA 3′ end formation: a new genetic mechanism contributing to hereditary thrombophilia (2001) (264)
- A conserved motif in Argonaute-interacting proteins mediates functional interactions through the Argonaute PIWI domain (2007) (253)
- c-Src-Mediated Phosphorylation of hnRNP K Drives Translational Activation of Specifically Silenced mRNAs (2002) (231)
- The liver-specific microRNA miR-122 controls systemic iron homeostasis in mice. (2011) (228)
- The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest (2019) (224)
- eIF4G--A Multipurpose Ribosome Adapter? (1997) (224)
- Nitric oxide signaling to iron-regulatory protein: direct control of ferritin mRNA translation and transferrin receptor mRNA stability in transfected fibroblasts. (1995) (219)
- Altered body iron distribution and microcytosis in mice deficient in iron regulatory protein 2 (IRP2). (2005) (217)
- Bruno Acts as a Dual Repressor of oskar Translation, Promoting mRNA Oligomerization and Formation of Silencing Particles (2006) (216)
- RNA-binding proteins in Mendelian disease. (2013) (214)
- 15 Translational Control of Developmental Decisions (1996) (209)
- NMD: RNA biology meets human genetic medicine. (2010) (207)
- Photo-cross-linking and high-resolution mass spectrometry for assignment of RNA-binding sites in RNA-binding proteins (2014) (201)
- Picornavirus IRESes and the poly(A) tail jointly promote cap-independent translation in a mammalian cell-free system. (2000) (201)
- A cis-acting element is necessary and sufficient for translational regulation of human ferritin expression in response to iron. (1987) (200)
- Metabolic Enzymes Enjoying New Partnerships as RNA-Binding Proteins (2015) (190)
- Nitric oxide and oxidative stress (H2O2) control mammalian iron metabolism by different pathways (1996) (189)
- The hemochromatosis proteins HFE, TfR2, and HJV form a membrane-associated protein complex for hepcidin regulation. (2012) (184)
- Pathways for the regulation of macrophage iron metabolism by the anti-inflammatory cytokines IL-4 and IL-13. (1997) (183)
- A cytosolic protein binds to structural elements within the iron regulatory region of the transferrin receptor mRNA. (1989) (181)
- Translational control of 5-aminolevulinate synthase mRNA by iron-responsive elements in erythroid cells. (1993) (181)
- Translational regulation of mammalian and Drosophila citric acid cycle enzymes via iron-responsive elements. (1996) (181)
- Cytoplasmic regulatory functions of the KH-domain proteins hnRNPs K and E1/E2. (1998) (175)
- Translation driven by an eIF4G core domain in vivo (1999) (175)
- Iron regulatory proteins are essential for intestinal function and control key iron absorption molecules in the duodenum. (2008) (174)
- Disassembly of Exon Junction Complexes by PYM (2009) (170)
- Mechanism of translational regulation by miR-2 from sites in the 5' untranslated region or the open reading frame. (2010) (168)
- System-wide identification of RNA-binding proteins by interactome capture (2013) (167)
- The IRP1-HIF-2α axis coordinates iron and oxygen sensing with erythropoiesis and iron absorption. (2013) (167)
- Homodirectional changes in transcriptome composition and mRNA translation induced by rapamycin and heat shock (2003) (167)
- Differences in the Regulation of Iron Regulatory Protein-1 (IRP-1) by Extra- and Intracellular Oxidative Stress* (1997) (161)
- Mouse brains deficient in H‐ferritin have normal iron concentration but a protein profile of iron deficiency and increased evidence of oxidative stress (2003) (159)
- Homology between IRE-BP, a regulatory RNA-binding protein, aconitase, and isopropylmalate isomerase. (1991) (159)
- Bone morphogenetic protein (BMP)-responsive elements located in the proximal and distal hepcidin promoter are critical for its response to HJV/BMP/SMAD (2009) (157)
- From factors to mechanisms: translation and translational control in eukaryotes. (1999) (155)
- Ca2+ channel blockers reverse iron overload by a new mechanism via divalent metal transporter-1 (2007) (152)
- Proteins binding to 5' untranslated region sites: a general mechanism for translational regulation of mRNAs in human and yeast cells (1994) (151)
- Hfe acts in hepatocytes to prevent hemochromatosis. (2007) (150)
- Position is the critical determinant for function of iron-responsive elements as translational regulators (1992) (146)
- RNA-binding proteins in human genetic disease (2020) (139)
- Iron-regulatory proteins secure iron availability in cardiomyocytes to prevent heart failure (2016) (137)
- A novel inflammatory pathway mediating rapid hepcidin-independent hypoferremia. (2014) (137)
- In Planta Determination of the mRNA-Binding Proteome of Arabidopsis Etiolated Seedlings (2016) (136)
- Recombinant iron-regulatory factor functions as an iron-responsive-element-binding protein, a translational repressor and an aconitase. A functional assay for translational repression and direct demonstration of the iron switch. (1993) (136)
- A bone morphogenetic protein (BMP)-responsive element in the hepcidin promoter controls HFE2-mediated hepatic hepcidin expression and its response to IL-6 in cultured cells (2008) (136)
- Regulation of interaction of the iron-responsive element binding protein with iron-responsive RNA elements (1989) (134)
- Activation of iron regulatory protein-1 by oxidative stress in vitro. (1998) (133)
- Functions of hUpf3a and hUpf3b in nonsense-mediated mRNA decay and translation. (2006) (132)
- Unusual bipartite mode of interaction between the nonsense‐mediated decay factors, UPF1 and UPF2 (2009) (130)
- Mechanism of escape from nonsense-mediated mRNA decay of human beta-globin transcripts with nonsense mutations in the first exon. (2011) (129)
- Enzymes as RNA-binding proteins: a role for (di)nucleotide-binding domains? (1994) (128)
- miChip: an array-based method for microRNA expression profiling using locked nucleic acid capture probes (2008) (126)
- Translational Control via Protein-Regulated Upstream Open Reading Frames (2011) (126)
- The Hierarchy of Exon-Junction Complex Assembly by the Spliceosome Explains Key Features of Mammalian Nonsense-Mediated mRNA Decay (2009) (125)
- Atherosclerosis is aggravated by iron overload and ameliorated by dietary and pharmacological iron restriction. (2019) (125)
- Translational control of dosage compensation in Drosophila by Sex‐lethal: cooperative silencing via the 5′ and 3′ UTRs of msl‐2 mRNA is independent of the poly(A) tail (1999) (124)
- SMAD7 controls iron metabolism as a potent inhibitor of hepcidin expression. (2010) (124)
- Global changes of the RNA-bound proteome during the maternal-to-zygotic transition in Drosophila (2016) (123)
- Translational repression by a complex between the iron‐responsive element of ferritin mRNA and its specific cytoplasmic binding protein is position‐dependent in vivo. (1990) (123)
- Iron Regulation and the Cell Cycle (2006) (119)
- An Hfe-dependent pathway mediates hyposideremia in response to lipopolysaccharide-induced inflammation in mice (2004) (118)
- Translational regulation by mRNA/protein interactions in eukaryotic cells: Ferritin and beyond (1993) (117)
- The abundance of RNPS1, a protein component of the exon junction complex, can determine the variability in efficiency of the Nonsense Mediated Decay pathway (2007) (117)
- Iron regulatory proteins secure mitochondrial iron sufficiency and function. (2010) (117)
- Iron-Mediated Degradation of IRP2, an Unexpected Pathway Involving a 2-Oxoglutarate-Dependent Oxygenase Activity (2004) (116)
- Coordination of cellular iron metabolism by post-transcriptional gene regulation. (1992) (116)
- PABP and the poly(A) tail augment microRNA repression by facilitated miRISC binding (2012) (115)
- Human Cytoplasmic Aconitase (Iron Regulatory Protein 1) Is Converted into Its [3Fe-4S] Form by Hydrogen Peroxide in Vitro but Is Not Activated for Iron-responsive Element Binding* (1999) (113)
- microRNA-Mediated Messenger RNA Deadenylation Contributes to Translational Repression in Mammalian Cells (2009) (113)
- The iron-responsive element binding protein: a method for the affinity purification of a regulatory RNA-binding protein. (1989) (112)
- Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture (2018) (110)
- Iron regulatory protein-1 and -2: transcriptome-wide definition of binding mRNAs and shaping of the cellular proteome by iron regulatory proteins. (2011) (109)
- Modulation of the RNA-binding activity of a regulatory protein by iron in vitro: switching between enzymatic and genetic function? (1992) (109)
- Determinants and regulation of cytoplasmic mRNA stability in eukaryotic cells. (1991) (109)
- A Dual Inhibitory Mechanism Restricts msl-2 mRNA Translation for Dosage Compensation in Drosophila (2005) (105)
- New Ways of Initiating Translation in Eukaryotes? (2001) (104)
- The Drosophila splicing regulator sex-lethal directly inhibits translation of male-specific-lethal 2 mRNA. (1998) (103)
- The REM phase of gene regulation. (2010) (102)
- A model for the structure and functions of iron-responsive elements. (1988) (102)
- Integration of splicing, transport and translation to achieve mRNA quality control by the nonsense-mediated decay pathway (2002) (101)
- Iron Inactivates the RNA Polymerase NS5B and Suppresses Subgenomic Replication of Hepatitis C Virus* (2005) (101)
- The Small Non-coding Vault RNA1-1 Acts as a Riboregulator of Autophagy (2017) (101)
- The Cardiomyocyte RNA-Binding Proteome: Links to Intermediary Metabolism and Heart Disease (2016) (99)
- Sex-lethal imparts a sex-specific function to UNR by recruiting it to the msl-2 mRNA 3' UTR: translational repression for dosage compensation. (2006) (98)
- Enhancement of IRES-mediated translation of the c-myc and BiP mRNAs by the poly(A) tail is independent of intact eIF4G and PABP. (2004) (96)
- Iron Induces Anti-tumor Activity in Tumor-Associated Macrophages (2017) (96)
- Resistance of ferroportin to hepcidin binding causes exocrine pancreatic failure and fatal iron overload. (2014) (95)
- HFE downregulates iron uptake from transferrin and induces iron-regulatory protein activity in stably transfected cells. (1999) (95)
- Overexpression of the ferritin H subunit in cultured erythroid cells changes the intracellular iron distribution. (1996) (95)
- The yeast nuclear cap binding complex can interact with translation factor eIF4G and mediate translation initiation. (2000) (94)
- Abnormally spliced beta-globin mRNAs: a single point mutation generates transcripts sensitive and insensitive to nonsense-mediated mRNA decay. (2002) (93)
- Pathologies at the nexus of blood coagulation and inflammation: thrombin in hemostasis, cancer, and beyond (2013) (93)
- Translational activation of uncapped mRNAs by the central part of human eIF4G is 5' end-dependent. (1998) (92)
- Control of oskar mRNA translation by Bruno in a novel cell-free system from Drosophila ovaries. (2000) (90)
- Ferritin-Mediated Iron Sequestration Stabilizes Hypoxia-Inducible Factor-1α upon LPS Activation in the Presence of Ample Oxygen. (2015) (90)
- Eukaryotic translation initiation factor 4GI and p97 promote cellular internal ribosome entry sequence-driven translation. (2005) (89)
- The SXL-UNR corepressor complex uses a PABP-mediated mechanism to inhibit ribosome recruitment to msl-2 mRNA. (2009) (88)
- From cis-regulatory elements to complex RNPs and back. (2012) (85)
- Splicing and 3′ end formation in the definition of nonsense‐mediated decay‐competent human β‐globin mRNPs (2001) (85)
- Nonsense-mediated mRNA decay: from vacuum cleaner to Swiss army knife (2004) (84)
- Condensation of Ded1p Promotes a Translational Switch from Housekeeping to Stress Protein Production (2020) (84)
- The human intronless melanocortin 4-receptor gene is NMD insensitive. (2002) (83)
- Splicing factors stimulate polyadenylation via USEs at non‐canonical 3′ end formation signals (2007) (82)
- Using the λN Peptide to Tether Proteins to RNAs (2004) (82)
- Iron Regulatory Proteins Mediate Host Resistance to Salmonella Infection. (2015) (81)
- IRP1 Activation by Extracellular Oxidative Stress in the Perfused Rat Liver* (2001) (81)
- Drosophila miR2 primarily targets the m7GpppN cap structure for translational repression. (2009) (80)
- Iron regulatory proteins control a mucosal block to intestinal iron absorption. (2013) (79)
- Dual function of UPF3B in early and late translation termination (2017) (79)
- Insights into the design and interpretation of iCLIP experiments (2017) (78)
- The prothrombin 3'end formation signal reveals a unique architecture that is sensitive to thrombophilic gain-of-function mutations. (2004) (78)
- Physiologic systemic iron metabolism in mice deficient for duodenal Hfe. (2007) (77)
- Drosophila sex-lethal inhibits the stable association of the 40S ribosomal subunit with msl-2 mRNA. (2003) (75)
- Cloning, characterization, expression, and chromosomal localization of a human ferritin heavy-chain gene. (1986) (75)
- SIREs: searching for iron-responsive elements (2010) (74)
- FASTKD2 is an RNA-binding protein required for mitochondrial RNA processing and translation (2015) (73)
- Inactivation of Both RNA Binding and Aconitase Activities of Iron Regulatory Protein-1 by Quinone-induced Oxidative Stress* (1999) (72)
- From Transcript to Protein (1996) (70)
- miChip: a microarray platform for expression profiling of microRNAs based on locked nucleic acid (LNA) oligonucleotide capture probes. (2007) (70)
- Nuclear degradation of nonsense mutated beta-globin mRNA: a post-transcriptional mechanism to protect heterozygotes from severe clinical manifestations of beta-thalassemia? (1995) (70)
- Iron regulatory factor--the conductor of cellular iron regulation. (1993) (69)
- p38 MAPK controls prothrombin expression by regulated RNA 3' end processing. (2011) (69)
- The iron-responsive element is the single element responsible for iron-dependent translational regulation of ferritin biosynthesis. Evidence for function as the binding site for a translational repressor. (1988) (69)
- Determination of mRNA fate by different RNA polymerase II promoters. (1993) (68)
- Differential regulation of two related RNA-binding proteins, iron regulatory protein (IRP) and IRPB. (1995) (68)
- Using the lambdaN peptide to tether proteins to RNAs. (2004) (68)
- Ribosomal Pausing and Scanning Arrest as Mechanisms of Translational Regulation from Cap-Distal Iron-Responsive Elements (1999) (67)
- Iron overload in adult Hfe-deficient mice independent of changes in the steady-state expression of the duodenal iron transporters DMT1 and Ireg1/ferroportin (2003) (67)
- Relationships and distinctions in iron-regulatory networks responding to interrelated signals. (2003) (64)
- Complex translational regulation of BACE1 involves upstream AUGs and stimulatory elements within the 5′ untranslated region (2007) (64)
- Identification of RNA-binding Proteins in Macrophages by Interactome Capture* (2016) (63)
- Exon Junction Complexes Show a Distributional Bias toward Alternatively Spliced mRNAs and against mRNAs Coding for Ribosomal Proteins (2016) (62)
- Translational regulation: versatile mechanisms for metabolic and developmental control. (1995) (61)
- Iron‐sulphur clusters as genetic regulatory switches: the bifunctional iron regulatory protein‐1 (1996) (60)
- Finding the hairpin in the haystack: searching for RNA motifs. (1995) (60)
- Effect of nitric oxide on expression of transferrin receptor and ferritin and on cellular iron metabolism in K562 human erythroleukemia cells. (1995) (60)
- Unbiased RNAi screen for hepcidin regulators links hepcidin suppression to proliferative Ras/RAF and nutrient-dependent mTOR signaling. (2014) (59)
- The uORF-containing thrombopoietin mRNA escapes nonsense-mediated decay (NMD) (2006) (57)
- Iron homeostasis in the brain: complete iron regulatory protein 2 deficiency without symptomatic neurodegeneration in the mouse (2006) (56)
- Iron regulatory protein 1 sustains mitochondrial iron loading and function in frataxin deficiency. (2015) (53)
- A co‐repressor assembly nucleated by Sex‐lethal in the 3′UTR mediates translational control of Drosophila msl‐2 mRNA (2003) (52)
- Bacteriophage and spliceosomal proteins function as position-dependent cis/trans repressors of mRNA translation in vitro. (1992) (51)
- Targeted mutagenesis of the murine IRP1 and IRP2 genes reveals context-dependent RNA processing differences in vivo. (2004) (50)
- A chemiluminescence-based reporter system to monitor nonsense-mediated mRNA decay. (2006) (50)
- 5-azacytidine inhibits nonsense-mediated decay in a MYC-dependent fashion (2014) (49)
- Comprehensive Identification of RNA-Binding Proteins by RNA Interactome Capture. (2016) (49)
- A network of SMG-8, SMG-9 and SMG-1 C-terminal insertion domain regulates UPF1 substrate recruitment and phosphorylation (2015) (49)
- Probing the structure of the regulatory region of human transferrin receptor messenger RNA and its interaction with iron regulatory protein-1. (1997) (48)
- Influence of altered transcription on the translational control of human ferritin expression. (1987) (47)
- Cell-autonomous and systemic context-dependent functions of iron regulatory protein 2 in mammalian iron metabolism. (2009) (47)
- Tethered-function analysis reveals that elF4E can recruit ribosomes independent of its binding to the cap structure. (2001) (44)
- Translational repression by the human iron-regulatory factor (IRF) in Saccharomyces cerevisiae. (1993) (44)
- Generation of conditional alleles of the murine iron regulatory protein (IRP)‐1 and ‐2 genes (2005) (44)
- Nitric oxide and the post-transcriptional control of cellular iron traffic. (1994) (44)
- Molecular analysis of iron overload in beta2-microglobulin-deficient mice. (2004) (43)
- Regulated ribosomal frameshifting by an RNA-protein interaction. (1996) (43)
- Specific RNP capture with antisense LNA/DNA mixmers (2017) (42)
- A translational repression assay procedure (TRAP) for RNA-protein interactions in vivo. (1998) (42)
- An efficient factor-depleted mammalian in vitro translation system (2011) (42)
- Anti-hemojuvelin antibody corrects anemia caused by inappropriately high hepcidin levels (2016) (41)
- Complexes between the nonsense-mediated mRNA decay pathway factor human upf1 (up-frameshift protein 1) and essential nonsense-mediated mRNA decay factors in HeLa cells. (2003) (41)
- Expression of the subgenomic hepatitis C virus replicon alters iron homeostasis in Huh7 cells. (2007) (40)
- The RNA-binding protein YBX1 regulates epidermal progenitors at a posttranscriptional level (2018) (40)
- Generation of stable mRNA fragments and translation of N-truncated proteins induced by antisense oligodeoxynucleotides. (2001) (39)
- Silica-based solid-phase extraction of cross-linked nucleic acid–bound proteins (2018) (39)
- Cis-regulatory sequences and trans-acting factors in translation control (2007) (38)
- A versatile assay for RNA-binding proteins in living cells (2014) (38)
- 3′ End Processing of the Prothrombin mRNA in Thrombophilia (2006) (38)
- mRNA 3′end processing: A tale of the tail reaches the clinic (2013) (36)
- Iron Regulatory Protein-1 Protects against Mitoferrin-1-deficient Porphyria* (2014) (35)
- Systems analysis of iron metabolism: the network of iron pools and fluxes (2010) (34)
- The RNA-Binding Protein YBX3 Controls Amino Acid Levels by Regulating SLC mRNA Abundance. (2019) (31)
- Mice with hepcidin‐resistant ferroportin accumulate iron in the retina (2016) (30)
- The prothrombin 20209 C→T mutation in Jewish‐Moroccan Caucasians: molecular analysis of gain‐of‐function of 3′ end processing (2006) (30)
- Expression of epithelial cell iron‐related genes upon infection by Neisseria meningitidis (2004) (30)
- Improved binding site assignment by high-resolution mapping of RNA–protein interactions using iCLIP (2015) (29)
- Identification of RNA-binding domains of RNA-binding proteins in cultured cells on a system-wide scale with RBDmap (2017) (29)
- IRP1-independent alterations of cardiac iron metabolism in doxorubicin-treated mice (2006) (28)
- The differential expression of alternatively polyadenylated transcripts is a common stress-induced response mechanism that modulates mammalian mRNA expression in a quantitative and qualitative fashion (2016) (28)
- Systematic genomic screening and analysis of mRNA in untranslated regions and mRNA precursors: combining experimental and computational approaches (1998) (27)
- Plasticity of nuclear and cytoplasmic stress responses of RNA-binding proteins (2020) (27)
- A poly(A) tail-responsive in vitro system for cap- or IRES-driven translation from HeLa cells. (2004) (26)
- Chromosomal localization of nucleic acid-binding proteins by affinity mapping: assignment of the IRE-binding protein gene to human chromosome 9. (1989) (26)
- Translation initiation by the c-myc mRNA internal ribosome entry sequence and the poly(A) tail. (2008) (26)
- Proteomic Analysis Reveals Branch-specific Regulation of the Unfolded Protein Response by Nonsense-mediated mRNA Decay* (2016) (25)
- Construction of regulatable picornavirus IRESes as a test of current models of the mechanism of internal translation initiation. (2001) (25)
- Believe It or Not--Translation in the Nucleus (2001) (24)
- Characterization of the African Swine Fever Virus Decapping Enzyme during Infection (2017) (24)
- Internal ribosome entry sequence‐mediated translation initiation triggers nonsense‐mediated decay (2006) (23)
- The interaction of the cap-binding complex (CBC) with eIF4G is dispensable for translation in yeast. (2003) (22)
- ‘High vault-age’: non-coding RNA control of autophagy (2020) (20)
- Tethering assays to investigate nonsense-mediated mRNA decay activating proteins. (2008) (20)
- Ligand-induced Structural Alterations in Human Iron Regulatory Protein-1 Revealed by Protein Footprinting* (1999) (20)
- Global analysis of RNA-binding protein dynamics by comparative and enhanced RNA interactome capture (2020) (19)
- Nitric Oxide, Oxygen Radicals, and Iron Metabolism (2000) (16)
- Abnormal body iron distribution and erythropoiesis in a novel mouse model with inducible gain of iron regulatory protein (IRP)-1 function (2013) (16)
- The actin-binding protein profilin 2 is a novel regulator of iron homeostasis. (2017) (16)
- The Role of the 5′ Untranslated Region of Eukaryotic Messenger RNAs in Translation and Its Investigation Using Antisense Technologies (1994) (15)
- Studying translational control in Drosophila cell-free systems. (2007) (15)
- Iron-sulfur clusters and oxidant stress responses. (1996) (15)
- The Molecular Circuitry Regulating the Switch between Iron Deficiency and Overload in Mice* (2006) (15)
- NMD inhibition by 5-azacytidine augments presentation of immunogenic frameshift-derived neoepitopes (2021) (13)
- Abnormally spliced b-globin mRNAs : a single point mutation generates transcripts sensitive and insensitive to nonsense-mediated mRNA decay (2002) (13)
- Modulation of ferritin H-chain expression in Friend erythroleukemia cells: transcriptional and translational regulation by hemin. (1992) (13)
- Protein (IRE/IRP) Regulatory Network (2008) (12)
- Focus Quality Control 3 0 end mRNA processing: molecular mechanisms and implications for health and disease (2008) (12)
- In vivo role(s) of the iron regulatory proteins (IRP) 1 and 2 in aseptic local inflammation (2009) (12)
- Tolerable upper intakes for dietary iron set by the US Food and Nutrition Board. (2002) (12)
- Riboregulation of Enolase 1 activity controls glycolysis and embryonic stem cell differentiation. (2022) (11)
- Identification of target mRNAs of regulatory RNA-binding proteins using mRNP immunopurification and microarrays (2007) (10)
- RNA regulates Glycolysis and Embryonic Stem Cell Differentiation via Enolase 1 (2020) (10)
- Translational control by iron-responsive elements. (1994) (10)
- Molecular cloning and characterisation of a novel duodenal-specific gene implicated in iron absorption. (1998) (10)
- Making sense of nonsense (2013) (10)
- Automated High-Throughput RNAi Screening in Human Cells Combined with Reporter mRNA Transfection to Identify Novel Regulators of Translation (2012) (9)
- The Human RNA-Binding Proteome and Its Dynamics During Arsenite-Induced Translational Arrest (2018) (8)
- IRES unplugged (2016) (8)
- Core Cross‐Linked Polymeric Micelles for Specific Iron Delivery: Inducing Sterile Inflammation in Macrophages (2021) (8)
- Cellular citrate levels establish a regulatory link between energy metabolism and the hepatic iron hormone hepcidin (2017) (8)
- Translational control of 15-lipoxygenase and msl-2 mRNAs: single regulators or corepressor assemblies? (2001) (8)
- Fertility facts: male and female germ cell development requires translational control by CPEB. (2001) (7)
- Stimulation of IRE-BP activity of IRF by tetrahydrobiopterin and cytokine dependent induction of nitric oxide synthase. (1994) (7)
- Blasticidin S inhibits mammalian translation and enhances production of protein encoded by nonsense mRNA (2021) (7)
- Translational regulation of ferritin biosynthesis by iron: a review. (1991) (7)
- Identification of dynamic RNA-binding proteins uncovers a Cpeb4-controlled regulatory cascade during pathological cell growth of cardiomyocytes. (2021) (7)
- Is congenital secondary erythrocytosis/polycythemia caused by activating mutations within the HIF-2 alpha iron-responsive element? (2007) (6)
- The IronChip evaluation package: a package of perl modules for robust analysis of custom microarrays (2010) (6)
- A new era for the RNA world (2000) (6)
- A Genetically Encoded Diazirine Analogue for RNA–Protein Photo‐crosslinking (2019) (6)
- Vault RNA emerges as a regulator of selective autophagy (2019) (6)
- Translational repression assay procedure: a method to study RNA-protein interactions in yeast. (2000) (5)
- Targeted Disruption of the Mouse Mitoferrin (Slc25A37) Mitochondrial Solute Carrier Results in Defective Primitive and Definitive Erythropoiesis. (2006) (5)
- Iron Regulation and the Cell Cycle IDENTIFICATION OF AN IRON-RESPONSIVE ELEMENT IN THE 3 (cid:1) -UNTRANSLATED REGION OF HUMAN CELL DIVISION CYCLE 14A mRNA BY A REFINED MICROARRAY-BASED SCREENING STRATEGY (2006) (4)
- Rat duodenal IRP1 activity and iron absorption in iron deficiency and after H2O2 perfusion (2004) (4)
- Constitutional PIGA mutations cause a novel subtype of hemochromatosis in patients with neurologic dysfunction. (2021) (4)
- Unbiased RNAi screen for hepcidin regulators links hepcidin suppression to the proliferative Ras/RAF and the nutrient-dependent mTOR signaling pathways Running title: Signaling networks regulating Hepcidin expression (2013) (4)
- Low-Iron Diet and Chelation Therapy Rescue Severe Atherosclerosis Associated with High Circulating Iron Levels (2016) (3)
- The RNA-binding protein landscapes differ between mammalian organs and cultured cells (2022) (2)
- Global analysis of RNA-binding protein dynamics by comparative and enhanced RNA interactome capture (2020) (2)
- Elisa Izaurralde 1959–2018 (2018) (2)
- A Role for the Protease Falcipain 1 in Host Cell Invasion by the Human Malaria Parasite (2002) (2)
- Low Cytosolic Non-Heme Iron Levels in Erythroid Cells Prevent IRP2-Mediated Ferritin Upregulation during Differentiation. (2007) (2)
- Iron accelerates cardiovascular disease: The importance of maintaining iron balance (2016) (2)
- htseq-clip: a toolset for the preprocessing of eCLIP/iCLIP datasets (2022) (2)
- Iron-dependent BMP6 Regulation in Liver Sinusoidal Endothelial Cells Is Instructed by Hepatocyte-derived Secretory Signals (2022) (1)
- Crystal structure of the complex between human nonsense mediated decay factors UPF1 and UPF2 Orthorhombic form (2009) (1)
- Low-iron diet and chelation therapy rescue severe atherosclerosis associated with high circulating iron levels. (2017) (1)
- 889 HFE ACTS IN HEPATOCYTES TO PREVENT HEMOCHROMATOSIS (2008) (1)
- High Circulating Iron Levels Are a Risk Factor for Cardiovascular Disease: Clinical Implications for Iron-Overload Conditions (2015) (1)
- Iron Regulatory Proteins in Systemic Iron Metabolism and Erythropoiesis (2011) (1)
- NMD and Human Disease (2013) (1)
- A Dual Inhibitory Mechanism Restricts msl-2 mRNA Translation for Dosage Compensation in Drosophila (2005) (1)
- Vault RNA1-1 riboregulates the autophagic function of p62 by binding to K7/R21 that are critical for p62 oligomerisation (2022) (1)
- Crystal structure of the complex between human nonsense mediated decay factors UPF1 and UPF2 (2009) (1)
- Pharmacological inhibition of nonsense-mediated RNA decay augments HLA class I-mediated presentation of neoepitopes in MSI CRC (2020) (1)
- Mechanistic insights into RNA binding and RNA-regulated RIG-I ubiquitination by TRIM25 (2020) (1)
- Complex formation between a cytoplasmic protein and the ferritin mRNA regulates translation initiation (2004) (1)
- Post-Transcriptional Regulation of Gene Expression by Iron (1995) (1)
- Elisa Izaurralde 1959–2018 (2018) (0)
- Overcoming inhibitions. Translational Control sponsored by the Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA, September 13-17, 1989. (1990) (0)
- EMBO Molecular Medicine: Conquering new frontiers (2009) (0)
- Iron-Regulatory Protein Activity in Stably Transfected Cells HFE Downregulates Iron Uptake From Transferrin and Induces (1999) (0)
- Profilin2 is controlled by the Iron Regulatory Proteins and modulates iron homeostasis (2014) (0)
- activating mutations within the HIF-2 { alpha } iron-responsive element ? Is congenital secondary erythrocytosis / polycythemia caused (2007) (0)
- Subject Index Vol. 115, 2006 (2006) (0)
- Iron sulfur proteins as effectors and targets of post-transcriptional gene regulation: Iron regulatory protein and its targets (1994) (0)
- S277: HYPOFERREMIA CAUSED BY FERROPORTIN DOWNREGULATION IS REGULATED BY NFКB THROUGH HDAC-DEPENDENT MECHANISMS (2022) (0)
- The RNA-binding protein YBX1 regulates epidermal progenitors at a posttranscriptional level (2018) (0)
- A Closer Look at Cellular Iron Metabolism in IRP2 Deficient Erythroblasts. (2008) (0)
- New insights into the molecular mechanisms underlying the pro-atherosclerotic and vasculo-toxic effect of iron (2020) (0)
- Erratum to: Insights into the design and interpretation of iCLIP experiments (2017) (0)
- Supplemental Data Bruno Acts as a Dual Repressor of oskar Translation , Promoting mRNA Oligomerization and Silencing Particle Formation (2006) (0)
- Iron as a risk factor for atherosclerosis: Confirming the iron hypothesis in a mouse model of hemochromatosis (2014) (0)
- and translational regulation by hemin. Friend erythroleukemia cells: transcriptional Modulation of ferritin H-chain expression in (2013) (0)
- Regulation of iron metabolism in higher eukaryotes: iron–sulfur centers as genetic switches (2008) (0)
- 871 YBX1 mediated translational control of the senescence secretome in epidermal progenitors (2017) (0)
- Translational Control in Eukaryotic Cells: Principles Learned from the IRE/IRF System (1996) (0)
- The Prothrombin C>T Mutation at Position 20209 (F2 20209*T) Promotes 3′end mRNA Processing and Thus Contributes to Thrombophilia through Gain-of-Function. (2005) (0)
- Running head: TLR2/6 mediated hepcidin-independent hypoferremia (2016) (0)
- Erratum to: Insights into the design and interpretation of iCLIP experiments (2017) (0)
- S1631 UNEXPECTED DIFFERENCES IN CARDIAC IRON METABOLISM AND SURVIVAL IN HAMP-KO AND FPN(C326S) MICE (2019) (0)
- Abstract IA21: New technologies to monitor and understand RNA-binding proteins in cancer cells (2017) (0)
- Dissecting the role of systemic versus macrophage iron levels for the pathogenesis of atherosclerosis (2015) (0)
- Advisory Board and Contents (2021) (0)
- An interview with Matthias Hentze. (2012) (0)
- Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture (2018) (0)
- transcripts sensitive and insensitive to nonsense-mediated mRNA decay -globin mRNAs: a single point mutation generates β Abnormally spliced (2013) (0)
- Faculty Opinions recommendation of Evidence for a pioneer round of mRNA translation: mRNAs subject to nonsense-mediated decay in mammalian cells are bound by CBP80 and CBP20. (2001) (0)
- Review Middle, and End: Translation Initiation in Eukaryotes (1997) (0)
- Rolling out the Red Carpet : Iron Metabolism in Erythroid Cells (2017) (0)
- DEWSeq addresses the pervasive disparity of crosslink site distributions in the discovery of RNA-binding protein binding sites in eCLIP data (2022) (0)
- Improved discovery of RNA-binding protein binding sites in eCLIP data using DEWSeq (2022) (0)
- Mechanism of riboregulation of p62 protein oligomerisation by vault RNA1-1 in selective autophagy (2021) (0)
- Small noncoding RNA interactome capture reveals pervasive, carbon source–dependent tRNA engagement of yeast glycolytic enzymes (2022) (0)
- 3.8 Apoptose (2000) (0)
- From Transcript to Protein Meeting Review (1996) (0)
- The Molecular Signature of Iron Metabolism in Polycythaemia Mice. (2005) (0)
- The Physiology of Prothrombin Gene Expression Integrates RNA Polyadenylation and Splicing in a Novel Regulatable 3′ RNP-Complex. (2006) (0)
- A conditional mouse model to study murine hemochromatosis (2005) (0)
- Identification of Dynamic RNA-Binding Proteins Uncovers a Cpeb4-Controlled Regulatory Cascade During Pathological Cell Growth of Cardiomyocytes (2020) (0)
- RNA-binding proteins in human genetic disease (2020) (0)
- Post-Transcriptional Regulation of Iron Metabolism (1996) (0)
- Insights into the design and interpretation of iCLIP experiments (2017) (0)
- In Vivo Disruption Of The Hepcidin−Ferroportin Regulatory Circuitry Causes Fatal Systemic and Exocrine Pancreatic Iron Overload (2013) (0)
- Hepatocyte Iron Content Controls BMP6-Dependent Hepcidin Regulation (2018) (0)
- Iron regulatory protein-1 protects against mitoferrin-1-deficient porphyria. (2014) (0)
- Advisory Board and Contents (2020) (0)
- Ferritin-Mediated Iron Seq uestration Stabilizes Hypoxia-Inducible Factor-1 a upon LPS Activation in the Presence of Ample Oxygen Graphical (2015) (0)
- Session I BASIC ASPECTS OF IRON BIOLOGY (2014) (0)
- The RBPome of influenza A virus mRNA reveals a role for TDP-43 in viral replication (2023) (0)
- The Cardiomyocyte RNA-B inding Proteome : Links to Intermediary Metabolism and Heart Disease Graphical (2016) (0)
- Cellular citrate levels establish a regulatory link between energy metabolism and the hepatic iron hormone hepcidin (2017) (0)
- Contents Vol. 115, 2006 (2006) (0)
- Sensing of Liver Iron Content Requires Cell-Cell Communication between Hepatocytes and Liver Sinusoidal Endothelial Cells (2019) (0)
- Pathologies at the nexus of blood coagulation and inflammation: thrombin in hemostasis, cancer, and beyond (2013) (0)
- Erratum: Iron regulatory protein-1 protects against mitoferrin-1-deficient porphyria (Journal of Biological Chemistry (2014) 289 (7835-7843)) (2014) (0)
- Vault RNA1–1 riboregulates the autophagic function of p62 by binding to lysine 7 and arginine 21, both of which are critical for p62 oligomerization (2022) (0)
- The role of nonsense‐mediated decay in physiological and pathological processes (2005) (0)
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