Maurizio Del Poeta
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Italian-born American lipid and cancer researcher
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Maurizio Del Poeta's Degrees
- PhD Microbiology University of Perugia
- Masters Microbiology University of Perugia
- Bachelors Biology University of Perugia
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Why Is Maurizio Del Poeta Influential?
(Suggest an Edit or Addition)According to Wikipedia, Maurizio Del Poeta is a Distinguished Professor in the Department of Microbiology and Immunology at the Stony Brook University Renaissance School of Medicine. His research focuses on novel anti-fungal drug discovery and lipid-mediated fungal pathogenesis.
Maurizio Del Poeta's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Calcineurin is essential for survival during membrane stress in Candida albicans (2002) (334)
- Ergosterol Biosynthesis Inhibitors Become Fungicidal when Combined with Calcineurin Inhibitors against Candida albicans, Candida glabrata, and Candida krusei (2003) (264)
- Glucosylceramide synthase is an essential regulator of pathogenicity of Cryptococcus neoformans. (2006) (203)
- Structure-In Vitro Activity Relationships of Pentamidine Analogues and Dication-Substituted Bis-Benzimidazoles as New Antifungal Agents (1998) (186)
- Role of Sphingolipids in Microbial Pathogenesis (2006) (182)
- Synergistic Antifungal Activities of Bafilomycin A1, Fluconazole, and the Pneumocandin MK-0991/Caspofungin Acetate (L-743,873) with Calcineurin Inhibitors FK506 and L-685,818 against Cryptococcus neoformans (2000) (170)
- Identification of App1 as a regulator of phagocytosis and virulence of Cryptococcus neoformans. (2003) (149)
- In vitro antifungal activity of pneumocandin L-743,872 against a variety of clinically important molds (1997) (147)
- Roles for inositol-phosphoryl ceramide synthase 1 (IPC1) in pathogenesis of C. neoformans. (2001) (141)
- Rapamycin and Less Immunosuppressive Analogs Are Toxic to Candida albicans and Cryptococcus neoformans via FKBP12-Dependent Inhibition of TOR (2001) (138)
- The immunosuppressant FK506 and its nonimmunosuppressive analog L-685,818 are toxic to Cryptococcus neoformans by inhibition of a common target protein (1997) (134)
- Depletion of Alveolar Macrophages Decreases the Dissemination of a Glucosylceramide-Deficient Mutant of Cryptococcus neoformans in Immunodeficient Mice (2007) (122)
- Immunosuppressive and Nonimmunosuppressive Cyclosporine Analogs Are Toxic to the Opportunistic Fungal Pathogen Cryptococcus neoformans via Cyclophilin-Dependent Inhibition of Calcineurin (2000) (121)
- Antifungal Activities of Antineoplastic Agents:Saccharomyces cerevisiae as a Model System To Study Drug Action (1999) (111)
- The Cryptococcal Enzyme Inositol Phosphosphingolipid-Phospholipase C Confers Resistance to the Antifungal Effects of Macrophages and Promotes Fungal Dissemination to the Central Nervous System (2006) (108)
- Identification of a New Class of Antifungals Targeting the Synthesis of Fungal Sphingolipids (2015) (105)
- Lipid signaling in pathogenic fungi. (2006) (100)
- Sphingomyelin synthases regulate production of diacylglycerol at the Golgi. (2008) (95)
- The Sphingolipid Pathway Regulates Pkc1 through the Formation of Diacylglycerol in Cryptococcus neoformans* (2004) (91)
- Topoisomerase I is essential in Cryptococcus neoformans: role In pathobiology and as an antifungal target. (1999) (90)
- Identification and characterization of the Cryptococcus neoformans phosphomannose isomerase‐encoding gene, MAN1, and its impact on pathogenicity (2001) (87)
- In Vitro Antifungal Activities of a Series of Dication-Substituted Carbazoles, Furans, and Benzimidazoles (1998) (85)
- Potential Roles of Fungal Extracellular Vesicles during Infection (2016) (83)
- Role of Phagocytosis in the Virulence of Cryptococcus neoformans (2004) (78)
- Lipid signalling in pathogenic fungi (2011) (76)
- Sphingosine‐1‐phosphate receptors and innate immunity (2018) (76)
- Plasma membrane lipids and their role in fungal virulence. (2016) (76)
- Secretion of cryptococcal phospholipase B1 (PLB1) is regulated by a glycosylphosphatidylinositol (GPI) anchor. (2005) (74)
- The Role and Mechanism of Diacylglycerol-Protein Kinase C1 Signaling in Melanogenesis by Cryptococcus neoformans* (2005) (73)
- Cryptococcus neoformans Differential Gene Expression Detected In Vitro and In Vivo with Green Fluorescent Protein (1999) (67)
- Synthesis and Biological Properties of Fungal Glucosylceramide (2014) (65)
- Sphingolipids as targets for treatment of fungal infections. (2016) (63)
- Extracellular Vesicle-Associated Transitory Cell Wall Components and Their Impact on the Interaction of Fungi with Host Cells (2016) (60)
- Methylation of glycosylated sphingolipid modulates membrane lipid topography and pathogenicity of Cryptococcus neoformans (2012) (59)
- Ten Challenges on Cryptococcus and Cryptococcosis (2012) (58)
- Comparison of In Vitro Activities of Camptothecin and Nitidine Derivatives against Fungal and Cancer Cells (1999) (58)
- The Anti-helminthic Compound Mebendazole Has Multiple Antifungal Effects against Cryptococcus neoformans (2017) (54)
- App1: An Antiphagocytic Protein That Binds to Complement Receptors 3 and 21 (2009) (53)
- Sphingolipids as Signaling and Regulatory Molecules (2010) (47)
- New insights on the development of fungal vaccines: from immunity to recent challenges (2015) (47)
- Acylhydrazones as Antifungal Agents Targeting the Synthesis of Fungal Sphingolipids (2018) (45)
- Cryptococcus neoformans Glucuronoxylomannan and Sterylglucoside Are Required for Host Protection in an Animal Vaccination Model (2019) (45)
- Transmission of fluconazole-resistant Candida albicans between patients with AIDS and oropharyngeal candidiasis documented by pulsed-field gel electrophoresis. (1995) (44)
- Raft-like membrane domains in pathogenic microorganisms. (2015) (44)
- Analysis of sphingolipids, sterols, and phospholipids in human pathogenic Cryptococcus strains[S] (2017) (43)
- Sphingolipidomics: An Important Mechanistic Tool for Studying Fungal Pathogens (2016) (42)
- The effect of sterol structure upon clathrin-mediated and clathrin-independent endocytosis (2017) (42)
- Role of sphingosine-1-phosphate (S1P) and S1P receptor 2 in the phagocytosis of Cryptococcus neoformans by alveolar macrophages. (2011) (41)
- Mathematical modeling of pathogenicity of Cryptococcus neoformans (2008) (41)
- Group IIA secreted phospholipase A2 is associated with the pathobiology leading to COVID-19 mortality. (2021) (40)
- Regulation of cytochrome c oxidase subunit 1 (COX1) expression in Cryptococcus neoformans by temperature and host environment. (2003) (40)
- Biological Roles Played by Sphingolipids in Dimorphic and Filamentous Fungi (2018) (39)
- Role of phagocytosis in the virulence of Cryptococcus neoformans. (2004) (39)
- Toward Developing a Universal Treatment for Fungal Disease Using Radioimmunotherapy Targeting Common Fungal Antigens (2012) (39)
- New potential targets for antifungal development (2000) (38)
- Pseudomonas aeruginosa Inhibits the Growth of Cryptococcus Species (2012) (38)
- The Role of Ceramide Synthases in the Pathogenicity of Cryptococcus neoformans (2018) (38)
- Prevalence and antifungal susceptibility of vaginal yeasts in outpatients attending a gynecological center in Ancona, Italy (1997) (35)
- Biosynthesis and Immunogenicity of Glucosylceramide in Cryptococcus neoformans and Other Human Pathogens (2007) (34)
- APP1 Transcription Is Regulated by Inositol-phosphorylceramide Synthase 1-Diacylglycerol Pathway and Is Controlled by ATF2 Transcription Factor in Cryptococcus neoformans* (2005) (31)
- Role of Sphingomyelin Synthase in Controlling the Antimicrobial Activity of Neutrophils against Cryptococcus neoformans (2010) (31)
- The Aspergillus fumigatus SchASCH9 kinase modulates SakAHOG1 MAP kinase activity and it is essential for virulence (2016) (30)
- Characterization of inositol phospho‐sphingolipid‐phospholipase C 1 (Isc1) in Cryptococcus neoformans reveals unique biochemical features (2011) (29)
- The Future of Antifungal Drug Therapy: Novel Compounds and Targets (2020) (29)
- Role of Sterylglucosidase 1 (Sgl1) on the pathogenicity of Cryptococcus neoformans: potential applications for vaccine development (2015) (29)
- Functional characterization of the Aspergillus nidulans glucosylceramide pathway reveals that LCB Δ8‐desaturation and C9‐methylation are relevant to filamentous growth, lipid raft localization and Psd1 defensin activity (2016) (28)
- Surface Localization of Glucosylceramide during Cryptococcus neoformans Infection Allows Targeting as a Potential Antifungal (2011) (28)
- Role of Host Sphingosine Kinase 1 in the Lung Response against Cryptococcosis (2010) (28)
- Changes in glucosylceramide structure affect virulence and membrane biophysical properties of Cryptococcus neoformans. (2017) (28)
- Inositol phosphosphingolipid phospholipase C1 regulates plasma membrane ATPase (Pma1) stability in Cryptococcus neoformans (2014) (27)
- Generational distribution of a Candida glabrata population: Resilient old cells prevail, while younger cells dominate in the vulnerable host (2017) (26)
- Glucosylceramide Administration as a Vaccination Strategy in Mouse Models of Cryptococcosis (2016) (23)
- The Granuloma Response Controlling Cryptococcosis in Mice Depends on the Sphingosine Kinase 1–Sphingosine 1-Phosphate Pathway (2015) (23)
- Lipid signaling in pathogenic fungi. (2009) (22)
- Lipid metabolism in Cryptococcus neoformans. (2006) (20)
- FTY720 reactivates cryptococcal granulomas in mice through S1P receptor 3 on macrophages. (2020) (20)
- Role of Glucose in the Expression of Cryptococcus neoformans Antiphagocytic Protein 1, App1 (2011) (20)
- Cryptococcus Neoformans Modulates Extracellular Killing by Neutrophils (2011) (18)
- Atf2 Transcription Factor Binds to the APP1 Promoter in Cryptococcus neoformans: Stimulatory Effect of Diacylglycerol (2007) (18)
- The putative flippase Apt1 is required for intracellular membrane architecture and biosynthesis of polysaccharide and lipids in Cryptococcus neoformans. (2017) (18)
- A VASt-domain protein regulates autophagy, membrane tension, and sterol homeostasis in rice blast fungus (2020) (18)
- Sphingolipids as Regulators of the Phagocytic Response to Fungal Infections (2015) (16)
- Macrophage cholesterol depletion and its effect on the phagocytosis of Cryptococcus neoformans. (2014) (16)
- Antifungal Drug Development: Targeting the Fungal Sphingolipid Pathway (2020) (16)
- Sphingolipid signaling in fungal pathogens. (2010) (16)
- Hydroxyurea treatment inhibits proliferation of Cryptococcus neoformans in mice (2012) (15)
- Metabolomics Analysis Identifies Sphingolipids as Key Signaling Moieties in Appressorium Morphogenesis and Function in Magnaporthe oryzae (2019) (15)
- Animal Models of Cryptococcus neoformans in Identifying Immune Parameters Associated With Primary Infection and Reactivation of Latent Infection (2020) (15)
- Imaging with mass spectrometry, the next frontier in sphingolipid research? A discussion on where we stand and the possibilities ahead. (2019) (14)
- Steryl Glycosides in Fungal Pathogenesis: An Understudied Immunomodulatory Adjuvant (2020) (14)
- SAR Studies on Aromatic Acylhydrazone-Based Inhibitors of Fungal Sphingolipid Synthesis as Next-Generation Antifungal Agents. (2019) (13)
- Fenbendazole controls in vitro growth, virulence potential and animal infection in the Cryptococcus model (2020) (13)
- In-vitro activity of dicationic aromatic compounds and fluconazole against Cryptococcus neoformans and Candida spp. (1999) (13)
- Unlocking the DEAD-box: a key to cryptococcal virulence? (2005) (13)
- Quantitation of cellular components in Cryptococcus neoformans for system biology analysis. (2011) (13)
- Cell Wall-Associated Virulence Factors Contribute to Increased Resilience of Old Cryptococcus neoformans Cells (2019) (13)
- Effect of pentamidine on the growth of Cryptococcus neoformans. (1994) (13)
- The AGC Kinase YpkA Regulates Sphingolipids Biosynthesis and Physically Interacts With SakA MAP Kinase in Aspergillus fumigatus (2019) (12)
- Sphingolipid biosynthetic pathway is crucial for growth, biofilm formation and membrane integrity of Scedosporium boydii. (2019) (12)
- The dynamics and role of sphingolipids in eukaryotic organisms upon thermal adaptation. (2020) (11)
- Identification of Antifungal Compounds against Multidrug-Resistant Candida auris Utilizing a High-Throughput Drug-Repurposing Screen (2021) (11)
- Pho85 and PI(4,5)P2 regulate different lipid metabolic pathways in response to cold. (2020) (10)
- Structure and inhibition of Cryptococcus neoformans sterylglucosidase to develop antifungal agents (2021) (10)
- Group IIA Secreted Phospholipase A2 Plays a Central Role in the Pathobiology of COVID-19 (2021) (10)
- Erratum for Mor et al., “Identification of a New Class of Antifungals Targeting the Synthesis of Fungal Sphingolipids” (2018) (9)
- Cryptococcus neoformans Δsgl1 Vaccination Requires Either CD4+ or CD8+ T Cells for Complete Host Protection (2021) (9)
- A novel small molecule methyltransferase is important for virulence in Candida albicans. (2013) (8)
- Turbidimetric and visual criteria for determining the in vitro activity of six antifungal agents againstCandida spp. andCryptococcus neoformans (1993) (8)
- Targeting fungal membrane homeostasis with imidazopyrazoindoles impairs azole resistance and biofilm formation (2022) (8)
- Sphingolipids as targets for microbial infections. (2006) (8)
- Transmembrane transporter expression regulated by the glucosylceramide pathway in Cryptococcus neoformans (2015) (7)
- Fungal sphingolipids: role in the regulation of virulence and potential as targets for future antifungal therapies (2020) (7)
- Three Models of Vaccination Strategies Against Cryptococcosis in Immunocompromised Hosts Using Heat-Killed Cryptococcus neoformans Δsgl1 (2022) (7)
- Fungal sphingolipids: role in the regulation of virulence and potential as targets for future antifungal therapies. (2020) (7)
- Detection of Antibody against Fungal Glucosylceramide in Immunocompromised Patients: A Potential New Diagnostic Approach for Cryptococcosis (2012) (7)
- Biochemical systems analysis of signaling pathways to understand fungal pathogenicity. (2011) (6)
- Preclinical Evaluation of Acylhydrazone SB-AF-1002 as a Novel Broad-Spectrum Antifungal Agent (2020) (6)
- The Heat Shock Transcription Factor HsfA Is Essential for Thermotolerance and Regulates Cell Wall Integrity in Aspergillus fumigatus (2021) (6)
- The presence of 3-hydroxy oxylipins in pathogenic microbes. (2012) (6)
- Screening of Chemical Libraries for New Antifungal Drugs against Aspergillus fumigatus Reveals Sphingolipids Are Involved in the Mechanism of Action of Miltefosine (2021) (6)
- The Interaction of Cryptococcus neoformans with Host MacroPhages and Neutrophils (2011) (6)
- Microdomain Protein Nce102 Is a Local Sensor of Plasma Membrane Sphingolipid Balance (2021) (5)
- Extracellular vesicles regulate yeast growth, biofilm formation, and yeast-to-hypha differentiation in Candida albicans (2021) (5)
- Qualitative and Quantitative Measurements of Sphingolipids by Mass Spectrometry (2015) (5)
- Turbidimetric and visual criteria for in vitro susceptibility testing of Cryptococcus neoformans clinical isolates (1994) (4)
- Editorial: Antifungal Pipeline: Build It Strong; Build It Better! (2022) (4)
- Extracellular Vesicles Regulate Biofilm Formation and Yeast-to-Hypha Differentiation in Candida albicans (2022) (4)
- Correction: Synthesis and Biological Properties of Fungal Glucosylceramide (2015) (4)
- Fenbendazole Controls In Vitro Growth, Virulence Potential, and Animal Infection in the Cryptococcus Model (2020) (4)
- Special Issue: Novel Antifungal Drug Discovery. (2016) (4)
- Cryptococcus and Cryptococcosis in the Twenty-First Century (2012) (4)
- Antifungal Activity of Acylhydrazone Derivatives against Sporothrix spp. (2021) (4)
- Vaccination with Live or Heat-Killed Aspergillus fumigatus ΔsglA Conidia Fully Protects Immunocompromised Mice from Invasive Aspergillosis (2022) (4)
- Exploiting Lipids to Develop Anticryptococcal Vaccines (2019) (3)
- Cholesterol and sphingomyelin are critical for Fcγ receptor-mediated phagocytosis of Cryptococcus neoformans by macrophages (2021) (3)
- Cryptococcal Meningitis Reported With Fingolimod Treatment Case Series (3)
- Secretory aspartyl proteinases induce neutrophil chemotaxis in vivo. (2016) (3)
- Expression and Characterization of Cryptococcus neoformans Recombinant App1 (2012) (3)
- Insights of roles played by septins in pathogenic fungi (2021) (3)
- Comparison of broth dilution and semisolid agar dilution for in vitro susceptibility testing of Cryptococcus neoformans. (1994) (2)
- Sphingolipids and Inositol Phosphates Regulate the Tau Protein Phosphorylation Status in Humanized Yeast (2020) (2)
- Regulation of sphingolipid synthesis by the G1/S transcription factor Swi4. (2021) (2)
- Vaccine protection by Cryptococcus neoformans Δsgl1 is mediated by γδ T cells via TLR2 signaling (2022) (2)
- Cryptococcal Meningitis Reported With Fingolimod Treatment (2022) (2)
- Special Issue: Novel Antifungal Drug Discovery (2016) (2)
- Fungal Infection of the CNS (2014) (2)
- Fungi are Not All "Fun-Guys" after All. (2010) (2)
- A Mechanism-Based Targeted Screen To Identify Epstein-Barr Virus-Directed Antiviral Agents (2020) (2)
- Lipid Metabolism in Model Fungi: The Achilles Heel of Fungal Pathogens (2016) (1)
- Pseudomonas aeruginosa Inhibits the Growth of Cryptococcus Species (2011) (1)
- Fungi are Not All “Fun-Guys” after All (2010) (1)
- Sphingolipid depletion suppresses UPR activation and promotes galactose hypersensitivity in yeast models of classic galactosemia. (2022) (1)
- Effects of Sterol Structure and Sterol Ability to form Ordered Membrane Domains upon Cellular Endocytosis (2016) (1)
- Cryptococcus–Neutrophil Interaction (2012) (0)
- RESULTS Three Genes in C . neoformans Encode Specific Acyl-CoA-Dependent Ceramide Synthases (2018) (0)
- Detection of Antibody against Fungal Glucosylceramide in Immunocompromised Patients: A Potential New Diagnostic Approach for Cryptococcosis (2011) (0)
- Transmembrane transporter expression regulated by the glucosylceramide pathway in Cryptococcus neoformans (2015) (0)
- Screening of chemical libraries for new antifungal drugs against Aspergillus fumigatus reveals the potential mechanism of action of miltefosine (2021) (0)
- Host sphingolipids and fungal infection. (2012) (0)
- Host populations, challenges, and commercialization of cryptococcal vaccines (2023) (0)
- Expression and Characterization of Cryptococcus neoformans Recombinant App1 (2011) (0)
- Cryptococcus and Cryptococcosis in the Twenty-First Century (2012) (0)
- Sterylglucosides in Fungi (2022) (0)
- Targeting Sterylglucosidase A to Treat Aspergillus fumigatus Infections (2023) (0)
- Internalization of the host alkaline pH signal in a fungal pathogen (2020) (0)
- Ten Challenges on Cryptococcus and Cryptococcosis (2011) (0)
- Mass Spectrometric Analysis of Bioactive Sphingolipids in Fungi. (2021) (0)
- Lipid Regulation in Pathogenic Fungi (2020) (0)
- Toward Developing a Universal Treatment for Fungal Disease Using Radioimmunotherapy Targeting Common Fungal Antigens (2011) (0)
- 2015 Anü fungal Drug Development Summit Speakers (2015) (0)
- Pharmacology and Cancer Biology, 2 Microbiology And (0)
- Acknowledgment to reviewers (2018) (0)
- , Alicja and Other Human Pathogens neoformans Cryptococcus Glucosylceramide in Biosynthesis and Immunogenicity of (2007) (0)
- Crystal structure of Cryptococcus neoformans sterylglucosidase 1 with hit 1 (2021) (0)
- Cryptococcus neoformans Inhibitors FK 506 and L-685 , 818 against Acetate ( L-743 , 873 ) with Calcineurin Pneumocandin MK-0991 / Caspofungin , Fluconazole , and the 1 Bafilomycin A Synergistic Antifungal Activities of (1999) (0)
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