Mel B. Feany
#121,832
Most Influential Person Now
American neuropathologist
Mel B. Feany's AcademicInfluence.com Rankings
Mel B. Feanymedical Degrees
Medical
#3534
World Rank
#4007
Historical Rank
#525
USA Rank
Neurology
#324
World Rank
#415
Historical Rank
#57
USA Rank
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Medical
Mel B. Feany's Degrees
- Doctorate Medicine Harvard University
Why Is Mel B. Feany Influential?
(Suggest an Edit or Addition)According to Wikipedia, Mel B. Feany is an American neuropathologist and geneticist at Brigham and Women's Hospital who researches neurodegenerative disease. She is a co-editor of the Annual Review of Pathology: Mechanisms of Disease.
Mel B. Feany's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A Drosophila model of Parkinson's disease (2000) (1986)
- Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants (2003) (1155)
- Sirtuin 2 Inhibitors Rescue α-Synuclein-Mediated Toxicity in Models of Parkinson's Disease (2007) (881)
- Tauopathy in Drosophila: Neurodegeneration Without Neurofibrillary Tangles (2001) (876)
- Parkinson's disease: genetics and pathogenesis. (2011) (724)
- α-Synuclein phosphorylation controls neurotoxicity and inclusion formation in a Drosophila model of Parkinson disease (2005) (552)
- Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease. (2007) (526)
- Alpha-synuclein acts in the nucleus to inhibit histone acetylation and promote neurotoxicity. (2006) (487)
- Abnormal bundling and accumulation of F-actin mediates tau-induced neuronal degeneration in vivo (2007) (420)
- Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy (2015) (340)
- Tau promotes neurodegeneration through global chromatin relaxation (2014) (332)
- Alpha-synuclein phosphorylation controls neurotoxicity and inclusion formation in a Drosophila model of Parkinson disease. (2005) (320)
- Tau Promotes Neurodegeneration via DRP1 Mislocalization In Vivo (2012) (308)
- Widespread cytoskeletal pathology characterizes corticobasal degeneration. (1995) (276)
- Neurodegenerative disorders with extensive tau pathology: A comparative study and review (1996) (273)
- Neuropathologic Overlap of Progressive Supranuclear Palsy, Pick's Disease and Corticobasal Degeneration (1996) (267)
- A neuropeptide gene defined by the Drosophila memory mutant amnesiac. (1995) (263)
- Genetic modifiers of tauopathy in Drosophila. (2003) (252)
- The synaptic vesicle protein SV2 is a novel type of transmembrane transporter (1992) (251)
- TOR-Mediated Cell-Cycle Activation Causes Neurodegeneration in a Drosophila Tauopathy Model (2006) (250)
- Oxidative stress mediates tau-induced neurodegeneration in Drosophila. (2007) (246)
- Cathepsin D expression level affects alpha-synuclein processing, aggregation, and toxicity in vivo (2009) (246)
- Aggregated α-Synuclein Mediates Dopaminergic Neurotoxicity In Vivo (2007) (221)
- Tyrosine and serine phosphorylation of alpha-synuclein have opposing effects on neurotoxicity and soluble oligomer formation. (2009) (213)
- Calpain-Cleavage of α-Synuclein : Connecting Proteolytic Processing to Disease-Linked Aggregation (2007) (194)
- Tau phosphorylation sites work in concert to promote neurotoxicity in vivo. (2007) (182)
- Modelling neurodegenerative diseases in Drosophila: a fruitful approach? (2002) (174)
- Clinical correlates in an experimental model of repetitive mild brain injury (2013) (158)
- Lamin Dysfunction Mediates Neurodegeneration in Tauopathies (2016) (150)
- Why size matters – balancing mitochondrial dynamics in Alzheimer's disease (2013) (147)
- Progressive aggregation despite chaperone associations of a mutant SOD1-YFP in transgenic mice that develop ALS (2009) (147)
- α-synuclein Induces Mitochondrial Dysfunction through Spectrin and the Actin Cytoskeleton (2018) (143)
- In Vivo Imaging Reveals Dissociation between Caspase Activation and Acute Neuronal Death in Tangle-Bearing Neurons (2008) (137)
- Functional screening in Drosophila identifies Alzheimer's disease susceptibility genes and implicates Tau-mediated mechanisms. (2014) (135)
- Lysosomal Dysfunction Promotes Cleavage and Neurotoxicity of Tau In Vivo (2010) (129)
- Calpain-cleavage of alpha-synuclein: connecting proteolytic processing to disease-linked aggregation. (2007) (127)
- Gene expression changes presage neurodegeneration in a Drosophila model of Parkinson's disease. (2003) (122)
- &agr;-Synuclein S129 Phosphorylation Mutants Do Not Alter Nigrostriatal Toxicity in a Rat Model of Parkinson Disease (2009) (110)
- Disease-related phenotypes in a Drosophila model of hereditary spastic paraplegia are ameliorated by treatment with vinblastine. (2005) (104)
- From fruit fly to bedside: translating lessons from Drosophila models of neurodegenerative disease (2003) (104)
- Comparison of pathways controlling toxicity in the eye and brain in Drosophila models of human neurodegenerative diseases. (2004) (103)
- Connecting the dots between tau dysfunction and neurodegeneration. (2015) (103)
- Parkin A Multipurpose Neuroprotective Agent? (2003) (103)
- S/P and T/P phosphorylation is critical for tau neurotoxicity in Drosophila (2007) (101)
- Cathepsin D-deficient Drosophila recapitulate the key features of neuronal ceroid lipofuscinoses (2005) (87)
- Inactivation of Drosophila Huntingtin affects long-term adult functioning and the pathogenesis of a Huntington’s disease model (2009) (86)
- The Unfolded Protein Response Protects from Tau Neurotoxicity In Vivo (2010) (83)
- Functional screening of Alzheimer pathology genome-wide association signals in Drosophila. (2011) (77)
- The synaptic vesicle proteins SV2, synaptotagmin and synaptophysin are sorted to separate cellular compartments in CHO fibroblasts (1993) (77)
- Rescue of the learning defect in dunce, a Drosophila learning mutant, by an allele of rutabaga, a second learning mutant. (1990) (76)
- Parkinson's disease: Insights from non-traditional model organisms (2010) (74)
- Glial Fibrillary Tangles and JAK/STAT-Mediated Glial and Neuronal Cell Death in a Drosophila Model of Glial Tauopathy (2010) (67)
- The synaptic vesicle protein synaptotagmin promotes formation of filopodia in fibroblasts (1993) (67)
- Protein Misfolding and Oxidative Stress Promote Glial-Mediated Neurodegeneration in an Alexander Disease Model (2011) (67)
- Cytoskeletal pathology in non-Alzheimer degenerative dementia: new lesions in diffuse Lewy body disease, Pick's disease, and corticobasal degeneration. (1996) (64)
- p53 prevents neurodegeneration by regulating synaptic genes (2014) (59)
- Accelerated Accumulation of Misfolded Prion Protein and Spongiform Degeneration in a Drosophila Model of Gerstmann–Sträussler–Scheinker Syndrome (2006) (56)
- Proliferative Potential of Human Astrocytes (2005) (55)
- A genetic basis for the variable effect of smoking/nicotine on Parkinson's disease (2012) (54)
- A neuroprotective role for the DNA damage checkpoint in tauopathy (2012) (51)
- New genetic insights into Parkinson's disease. (2004) (49)
- Alexander Disease (2012) (48)
- Defective Phagocytic Corpse Processing Results in Neurodegeneration and Can Be Rescued by TORC1 Activation (2016) (47)
- Epitope expression and hyperphosphorylation of tau protein in corticobasal degeneration: differentiation from progressive supranuclear palsy (2004) (45)
- Nitric oxide mediates glial-induced neurodegeneration in Alexander disease (2015) (42)
- Polyglutamines Stop Traffic Axonal Transport as a Common Target in Neurodegenerative Diseases (2003) (37)
- Lrrk promotes tau neurotoxicity through dysregulation of actin and mitochondrial dynamics (2018) (36)
- Yeast genetics targets lipids in Parkinson's disease. (2004) (35)
- Tissue and cellular rigidity and mechanosensitive signaling activation in Alexander disease (2018) (34)
- Studying Human Neurodegenerative Diseases in Flies and Worms (2000) (30)
- An In Vivo Pharmacological Screen Identifies Cholinergic Signaling as a Therapeutic Target in Glial-Based Nervous System Disease (2016) (30)
- Spinal lipoma controversy. (1999) (28)
- A Conserved Cytoskeletal Signaling Cascade Mediates Neurotoxicity of FTDP-17 Tau Mutations In Vivo (2017) (27)
- Nortriptyline inhibits aggregation and neurotoxicity of alpha-synuclein by enhancing reconfiguration of the monomeric form (2017) (26)
- α-synuclein impairs autophagosome maturation through abnormal actin stabilization (2021) (25)
- Connecting cell-cycle activation to neurodegeneration in Drosophila. (2007) (25)
- Post‐transcriptional suppression of pathogenic prion protein expression in Drosophila neurons (2003) (23)
- Glia are critical for the neuropathology of complex I deficiency in Drosophila. (2014) (23)
- PARP Inhibitors and Parkinson's Disease (2019) (21)
- The Parkinson’s disease protein alpha-synuclein is a modulator of processing bodies and mRNA stability (2022) (21)
- Mediators of a long-term movement abnormality in a Drosophila melanogaster model of classic galactosemia (2012) (21)
- August 2000: Two cases with necrosis and hemorrhage in the putamen and white matter. (2001) (20)
- Glial α‐synuclein promotes neurodegeneration characterized by a distinct transcriptional program in vivo (2019) (19)
- ASIP Outstanding Investigator Award Lecture. New approaches to the pathology and genetics of neurodegeneration. (2010) (17)
- Neuropeptide Modulation of Learning and Memory Processes (1996) (13)
- Biotin rescues mitochondrial dysfunction and neurotoxicity in a tauopathy model (2020) (11)
- Antisense therapy in a rat model of Alexander disease reverses GFAP pathology, white matter deficits, and motor impairment (2021) (10)
- > -Synuclein S129 Phosphorylation Mutants Do Not Alter Nigrostriatal Toxicity in a Rat Model of Parkinson Disease (2009) (9)
- Comparative proteomic analysis highlights metabolic dysfunction in α-synucleinopathy (2020) (9)
- Parkinson’s disease risk genes act in glia to control neuronal α-synuclein toxicity (2021) (8)
- Elevated Oxidative Stress and DNA Damage in Cortical Neurons of Chemotherapy Patients. (2021) (4)
- Precision medicine on the fly: using Drosophila to decipher gene-environment interactions in Parkinson's disease. (2021) (4)
- Oligomerization of Lrrk controls actin severing and α-synuclein neurotoxicity in vivo (2021) (3)
- COMPARISON OF NEUROFIBRILLARY LESIONS IN PROGRESSIVE SUPRANUCLEAR PALSY, PICKʼS DISEASE, AND CORTICOBASAL DEGENERATION: 146 (1995) (2)
- Reply (2014) (2)
- α-Synuclein Promotes Neuronal Dysfunction and Death by Disrupting the Binding of Ankyrin to β-Spectrin (2023) (1)
- Case Study 1: A 55-Year-Old Woman With Progressive Cognitive, Perceptual, and Motor Impairments. (2021) (1)
- Genetic influences and neuropathological sequelae of repetitive brain injury. Reply. (2014) (1)
- EFFECTS OF METHANOL POISONING ON THE CENTRAL NERVOUS SYSTEM (1998) (1)
- Anastasis Drives Senescence and Non-Cell Autonomous Neurodegeneration in the Astrogliopathy Alexander Disease (2022) (1)
- Drosophila models of Alzheimer's disease and related disorders (2010) (1)
- Iatrogenic Neuropathology of Systemic Therapies. (2020) (1)
- New-Onset Delusions Heralding an Underlying Neurodegenerative Condition: A Case Report and Review of the Literature. (2020) (1)
- Toward More Accessible Fully Automated 3D Volumetric MRI Decision Trees for the Differential Diagnosis of Multiple System Atrophy, Related Disorders, and Age-Matched Healthy Subjects. (2022) (1)
- Defining the pathologic contribution of glia to alpha-synucleinopathies (S45.001) (2018) (0)
- Comparative proteomic analysis highlights metabolic dysfunction in α-synucleinopathy (2020) (0)
- S3-01-02 Genetic analysis of tauopathy in Drosophila (2004) (0)
- Intergrating human and fly genetics to understand Alzheimer's disease susceptibility (2013) (0)
- Case Study 3: A 58-Year-Old Woman Referred for Evaluation of Suspected Alzheimer Dementia. (2022) (0)
- Connecting cell-cycle activation to neurodegeneration in (2020) (0)
- 9. Tau causes neurodegeneration in vivo through mitochondrial disruption (2009) (0)
- Case Study 4: A 68-Year-Old Woman With Progressive Cognitive Decline and Anxiety. (2023) (0)
- Correction to: Clinical trial-ready patient cohorts for multiple system atrophy: coupling biospecimen and iPSC banking to longitudinal deep-phenotyping. (2022) (0)
- Clinical Trial-Ready Patient Cohorts for Multiple System Atrophy: Coupling Biospecimen and iPSC Banking to Longitudinal Deep-Phenotyping (2022) (0)
- Knock‐in of P301L tau homolog in Drosophila leads to neuronal loss and widespread neurodegeneration (2022) (0)
- STAT3 Drives GFAP Accumulation and Astrocyte Pathology in a Mouse Model of Alexander Disease (2023) (0)
- Development of gene‐environment interaction model in Drosophila for neurodegenerative disease: A step towards personalized medicine (2019) (0)
- Integrating genome-wide association and functional validation to understand susceptibility for Alzheimer's pathology (2011) (0)
- Circular RNAs in the human brain are tailored to neuron identity and neuropsychiatric disease (2023) (0)
- TDP‐43/TBPH enhances neurotoxicity in a Drosophila model relevant to Alzheimerˈs disease (2012) (0)
- S2-03-05: The role of actin and oxidative stress in tau-associated neurodegeneration (2008) (0)
- 10 Corticobasal degeneration versus Picks' disease: An immunocytochemical comparison (1996) (0)
- HYBRID LESIONS WITH COMBINED FEATURES OF NEUROFIBROMA AND SCHWANNOMA (1997) (0)
- Cell cycle and neurodegeneration in fly (2009) (0)
- 1-1 Inactivation of Drosophila Huntingtin affects long-term adult functioning and the pathogenesis of a Huntington ’ s disease model (2010) (0)
- Multiplex analysis in a Drosophila gene‐environment model identifies interactions among LRRK2, rotenone and α‐synuclein (2020) (0)
- Editorial Board (2013) (0)
- Tissue and cellular rigidity and mechanosensitive signaling activation in Alexander disease (2018) (0)
- Antisense therapy in a new rat model of Alexander disease reverses GFAP pathology, white matter deficits, and motor impairment (2021) (0)
- Senseless makes sense for spinocerebellar ataxia-1 (2005) (0)
- Oligomerization of Lrrk controls actin severing and α-synuclein neurotoxicity in vivo (2021) (0)
- Nicotine-mediated rescue of α-synuclein toxicity requires synaptic vesicle glycoprotein 2 (2022) (0)
- DDH214 2011..2018 (2004) (0)
- ASTROCYTIC PROLIFERATION IN REACTIVE CONDITIONS (1998) (0)
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What Schools Are Affiliated With Mel B. Feany?
Mel B. Feany is affiliated with the following schools:
