Melissa S. Cline
American biologist
Melissa S. Cline's AcademicInfluence.com Rankings

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Biology
Melissa S. Cline's Degrees
- PhD Biological Sciences Stanford University
- Masters Biological Sciences Stanford University
- Bachelors Biology University of California, Santa Cruz
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Why Is Melissa S. Cline Influential?
(Suggest an Edit or Addition)According to Wikipedia, Melissa Suzanne Cline is an American biologist. She is an Associate Research Scientist at the UC Santa Cruz Genomics Institute Between June 2001 and December 2004 she was a staff scientist at Affymetrix, Inc. in Emeryville, California where she was involved in developing ANOSVA, a "statistical method to identify alternative spicing from expression data," during which she "analyzed the effects of alternative splicing on protein transmembrane and signal peptide regions". Subsequently, she moved to UC Santa Cruz, where she wrote on genome browsing. According to the Thomson Reuters report, she was one of the most highly cited scientists in the world in 2012/13.
Melissa S. Cline's Published Works
Published Works
- Integration of biological networks and gene expression data using Cytoscape (2007) (2342)
- An integrated encyclopedia of DNA elements in the human genome (2012) (2080)
- The UCSC Genome Browser database: update 2011 (2010) (1751)
- A User's Guide to the Encyclopedia of DNA Elements (ENCODE) (2011) (1467)
- A comparative encyclopedia of DNA elements in the mouse genome (2014) (1337)
- The UCSC Genome Browser database: extensions and updates 2013 (2012) (896)
- The UCSC Genome Browser database: extensions and updates 2011 (2011) (859)
- The UCSC Genome Browser database: 2014 update (2013) (698)
- Toil enables reproducible, open source, big biomedical data analyses (2017) (642)
- NetAffx: Affymetrix probesets and annotations (2003) (535)
- Nova regulates brain-specific splicing to shape the synapse (2005) (518)
- An encyclopedia of mouse DNA elements (Mouse ENCODE) (2012) (438)
- RBPmap: a web server for mapping binding sites of RNA-binding proteins (2014) (375)
- Aberrant alternative splicing and extracellular matrix gene expression in mouse models of myotonic dystrophy (2010) (317)
- ENCODE whole-genome data in the UCSC Genome Browser: update 2012 (2011) (299)
- Muscleblind-like 2-Mediated Alternative Splicing in the Developing Brain and Dysregulation in Myotonic Dystrophy (2012) (288)
- The UCSC Cancer Genomics Browser: update 2015 (2014) (283)
- Exploring TCGA Pan-Cancer Data at the UCSC Cancer Genomics Browser (2013) (249)
- Alternative splicing regulates mouse embryonic stem cell pluripotency and differentiation (2010) (222)
- Unusual Intron Conservation near Tissue-Regulated Exons Found by Splicing Microarrays (2005) (221)
- Hidden Markov models that use predicted local structure for fold recognition: Alphabets of backbone geometry (2003) (216)
- ENCODE whole-genome data in the UCSC genome browser (2011 update) (2010) (213)
- Predicting protein structure using hidden Markov models (1997) (182)
- Splicing biomarkers of disease severity in myotonic dystrophy (2013) (181)
- The UCSC Cancer Genomics Browser: update 2013 (2012) (179)
- Predicting protein structure using only sequence information (1999) (152)
- The Cancer Genomics Hub (CGHub): overcoming cancer through the power of torrential data (2014) (143)
- Quaking and PTB control overlapping splicing regulatory networks during muscle cell differentiation. (2013) (137)
- What is the value added by human intervention in protein structure prediction? (2001) (135)
- BRCA Challenge: BRCA Exchange as a global resource for variants in BRCA1 and BRCA2 (2018) (131)
- A Knowledge-Based Clustering Algorithm Driven by Gene Ontology (2004) (127)
- GOlorize: a Cytoscape plug-in for network visualization with Gene Ontology-based layout and coloring (2007) (113)
- Gene structure-based splice variant deconvolution using a microarry platform (2003) (111)
- Predicting reliable regions in protein sequence alignments (2002) (104)
- NetAffx Gene Ontology Mining Tool: a visual approach for microarray data analysis. (2004) (97)
- Using bioinformatics to predict the functional impact of SNVs (2011) (82)
- Evaluation of local structure alphabets based on residue burial (2004) (67)
- Information‐theoretic dissection of pairwise contact potentials (2002) (66)
- Exploring Biological Networks with Cytoscape Software (2008) (65)
- GA4GH: International policies and standards for data sharing across genomic research and healthcare (2021) (62)
- ANOSVA: a statistical method for detecting splice variation from expression data (2005) (57)
- Rbfox1 Downregulation and Altered Calpain 3 Splicing by FRG1 in a Mouse Model of Facioscapulohumeral Muscular Dystrophy (FSHD) (2013) (38)
- Consistency of BRCA1 and BRCA2 Variant Classifications Among Clinical Diagnostic Laboratories (2017) (34)
- The Effects of Alternative Splicing on Transmembrane Proteins in the Mouse Genome (2003) (31)
- Rapid and efficient analysis of 20,000 RNA-seq samples with Toil (2016) (27)
- Understanding genome browsing (2009) (24)
- Assessment of blind predictions of the clinical significance of BRCA1 and BRCA2 variants (2019) (19)
- International federation of genomic medicine databases using GA4GH standards (2021) (14)
- Matching phenotypes to whole genomes: Lessons learned from four iterations of the personal genome project community challenges (2017) (11)
- Affy exon tissues: exon levels in normal tissues in human, mouse and rat (2009) (11)
- Protein-based analysis of alternative splicing in the human genome (2002) (11)
- Exploring Alternative Transcript Structure in the Humangenome Using Blocks and Interpro (2003) (10)
- Integrating expression data with domain interaction networks (2008) (10)
- The GA4GH Variation Representation Specification: A computational framework for variation representation and federated identification (2021) (10)
- Abstract 5270: The UCSC Xena system for integrating and visualizing functional genomics (2016) (8)
- Data Sharing and Reproducible Clinical Genetic Testing: Successes and Challenges (2017) (8)
- The GA4GH Variation Representation Specification (VRS): a Computational Framework for the Precise Representation and Federated Identification of Molecular Variation (2021) (7)
- GPCR-GRAPA-LIB-a refined library of hidden Markov Models for annotating GPCRs (2003) (6)
- Thread 4: Data discovery, transparency and visualization (2013) (6)
- ON ALIGNMENT SHIFT AND ITS MEASURES (1998) (6)
- Protein sequence alignment reliability: prediction and measurement (2000) (5)
- NetAffx: affymetrix probeset annotations (2002) (5)
- Abstract LB-212: Treehouse Childhood Cancer Project: a resource for sharing and multiple cohort analysis of pediatric cancer genomics data (2015) (4)
- Structure-Based Comparison of Four Eukaryotic Genomes (2001) (4)
- Integrative Visual Analysis of the Effects of Alternative Splicing on Protein Domain Interaction Networks (2008) (3)
- Abstract B1-07: Using the UCSC Xena Platform to integrate, visualize, and analyze your own data in the context of large external genomic datasets (2015) (1)
- Development and application of a computable genotype model in the GA4GH Variation Representation Specification (2022) (1)
- AN EMPIRICAL STUDY OF THE BRANCH COVERAGE OF DIFFERENT FAULT CLASSES (1994) (1)
- An encyclopedia of mouse DNA elements (Mouse ENCODE) (2012) (1)
- The consequences of alternative splicing on biological pathways (2006) (1)
- during muscle cell differentiation Quaking and PTB control overlapping splicing regulatory networks Material (2013) (0)
- Toil enables reproducible, open source, big biomedical data analyses (2017) (0)
- P061: ATM and PALB2 variant curation guidelines progress update: ClinGen Hereditary Breast, Ovarian, and Pancreatic Cancer Variant Curation Expert Panel (2023) (0)
- P076: The ClinGen ENIGMA BRCA1/2 expert panel: A dynamic framework for evidence-based recommendations to improve classification criteria for variants in BRCA1/2* (2023) (0)
- The GA4GH Variation Representation Specification (VRS): a Computational Framework for the Precise Representation of Molecular Variation (2021) (0)
- Big Advocacy, Little Recognition: The Hidden Work of Black Patients in Precision Medicine (2023) (0)
- Abstract A33: Exploring pediatric cancer genomics with the UCSC Cancer Genomics Browser (2014) (0)
- Semantic Web for Data Interpretation & Integration: Lessons Learned from Scientific Publishing and the Distributed Annotation System Rdf-enanced Scientific Publications Advantages of Rdf for Data Encoding (2004) (0)
- Federated analysis of BRCA1 and BRCA2 variation in a Japanese cohort (2021) (0)
- Covariation of mutations: A computational approach for determination of function and structure from sequence (1998) (0)
- Modeling the impact of data sharing on variant classification (2021) (0)
- Variant classifications in BRCA1 and BRCA2: A systematic analysis of interlaboratory concordance (2016) (0)
- Abstract 1177: Introduction of the GA4GH Variation Representation Specification (VRS) and supporting tools for discovery and exchange of clinical genomic and cytogenomic knowledge in cancers (2022) (0)
- Erratum to: The Special Issue on “Computational Molecular Medicine”, edited by Rachel Karchin and Melissa S. Cline (2015) (0)
- Abstract PR14: Harnessing the power of big data to advance pediatric cancer care (2016) (0)
- Human genetics special issue on computational molecular medicine (2015) (0)
- A User ’ s Guide to the Encyclopedia of DNA Elements ( ENCODE ) The ENCODE Project Consortium (2011) (0)
- Human genetics special issue on computational molecular medicine (2015) (0)
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