Melvyn Greaves
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Melvyn Greaves's Degrees
- Masters Genetics University of Oxford
- PhD Molecular Biology Imperial College London
Why Is Melvyn Greaves Influential?
(Suggest an Edit or Addition)According to Wikipedia, Sir Melvyn Francis Greaves FMedSci, FRS is a British cancer biologist, and Professor of Cell Biology at the Institute of Cancer Research in London. He is noted for his research into childhood leukaemia and the roles of evolution in cancer, including important discoveries in the genetics and molecular biology underpinning leukaemia.
Melvyn Greaves's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Signatures of mutational processes in human cancer (2013) (7589)
- The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus (1984) (3590)
- Patterns of somatic mutation in human cancer genomes (2007) (3038)
- Genomic Classification and Prognosis in Acute Myeloid Leukemia. (2016) (2608)
- Somatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2. (2013) (1568)
- Clonal evolution in cancer (2012) (1564)
- Expression of the CD34 gene in vascular endothelial cells. (1990) (874)
- Genetic variegation of clonal architecture and propagating cells in leukaemia (2011) (815)
- Multilineage gene expression precedes commitment in the hemopoietic system. (1997) (793)
- Origins of chromosome translocations in childhood leukaemia (2003) (715)
- A one-step purification of membrane proteins using a high efficiency immunomatrix. (1982) (674)
- Ubiquitous cell-surface glycoprotein on tumor cells is proliferation-associated receptor for transferrin. (1981) (658)
- Compartmentalization of a haematopoietic growth factor (GM-CSF) by glycosaminoglycans in the bone marrow microenvironment (1987) (615)
- Chromosome translocations and covert leukemic clones are generated during normal fetal development (2002) (595)
- Lineage promiscuity in hemopoietic differentiation and leukemia. (1986) (588)
- Infection, immune responses and the aetiology of childhood leukaemia (2006) (585)
- Backtracking leukemia to birth: identification of clonotypic gene fusion sequences in neonatal blood spots. (1997) (524)
- Acute lymphoblastic leukaemia (2013) (515)
- Leukemia in twins: lessons in natural history. (2003) (502)
- Antisera to acute lymphoblastic leukemia cells. (1975) (490)
- ADULT T-CELL LYMPHOMA-LEUKAEMIA IN BLACKS FROM THE WEST INDIES (1982) (487)
- Altered adhesive interactions with marrow stroma of haematopoietic progenitor cells in chronic myeloid leukaemia (1987) (479)
- Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia (2009) (456)
- In utero rearrangements in the trithorax-related oncogene in infant leukaemias (1993) (440)
- Initiating and Cancer-Propagating Cells in TEL-AML1-Associated Childhood Leukemia (2008) (417)
- Differentiation-linked leukemogenesis in lymphocytes. (1986) (380)
- Lymphocyte activation. I. Response of T and B lymphocytes to phytomitogens. (1971) (376)
- P-24: a human leukemia-associated and lymphohemopoietic progenitor cell surface structure identified with monoclonal antibody (1981) (366)
- Ultrastructural localization of bcl-2 protein. (1992) (364)
- Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer (2014) (358)
- Identification, Enumeration, and Isolation of B and T Lymphocytes from Human Peripheral Blood (1974) (349)
- The cellular basis of immunological responses. A synthesis of some current views. (1969) (344)
- Purification of human T and B lymphocytes. (1974) (341)
- Methylenetetrahydrofolate reductase (MTHFR) polymorphisms and risk of molecularly defined subtypes of childhood acute leukemia (2001) (339)
- A novel abl protein expressed in Philadelphia chromosome positive acute lymphoblastic leukaemia positive acute lymphoblastic leukaemia (1987) (330)
- Fetal origins of the TEL-AML1 fusion gene in identical twins with leukemia. (1998) (321)
- Evolutionary determinants of cancer. (2015) (320)
- Transplacental chemical exposure and risk of infant leukemia with MLL gene fusion. (2001) (303)
- Activation of T and B lymphocytes by insoluble phytomitogens. (1972) (303)
- Speculations on the cause of childhood acute lymphoblastic leukemia. (1988) (301)
- RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia (2013) (301)
- A causal mechanism for childhood acute lymphoblastic leukaemia (2018) (292)
- Changes in cell surface antigen expression during hemopoietic differentiation. (1982) (282)
- In utero origin of t(8;21) AML1-ETO translocations in childhood acute myeloid leukemia. (2002) (279)
- Immunologically Defined Subclasses of Acute Lymphoblastic Leukaemia in Children: their Relationship to Presentation Features and Prognosis (1981) (279)
- Classifying the evolutionary and ecological features of neoplasms (2017) (276)
- Monoclonal antibodies OKT 11 and OKT 11A have pan‐T reactivity and block sheep erythrocyte “receptors” (1982) (266)
- ACUTE LYMPHOBLASTIC LEUKÆMIA IN CHILDREN: CLASSIFICATION AND PROGNOSIS (1977) (258)
- SELECTIVE TRIGGERING OF HUMAN T AND B LYMPHOCYTES IN VITRO BY POLYCLONAL MITOGENS (1974) (256)
- Protracted and variable latency of acute lymphoblastic leukemia after TEL-AML1 gene fusion in utero. (1999) (254)
- Variation in CDKN2A at 9p21.3 influences childhood acute lymphoblastic leukemia risk (2010) (253)
- Expression of cell-surface HLA-DR, HLA-ABC and glycophorin during erythroid differentiation (1981) (249)
- Patterns of gene expression and the cellular origins of human leukaemias. (1978) (241)
- Selective expression of the common acute lymphoblastic leukemia (gp 100) antigen on immature lymphoid cells and their malignant counterparts. (1983) (239)
- Phenotypic characterisation of a unique non-T, non-B acute lymphoblastic leukaemia cell line (1977) (237)
- A lack of a functional NAD(P)H:quinone oxidoreductase allele is selectively associated with pediatric leukemias that have MLL fusions. United Kingdom Childhood Cancer Study Investigators. (1999) (233)
- Terminal transferase-positive human bone marrow cells exhibit the antigenic phenotype of common acute lymphoblastic leukemia. (1979) (231)
- An infectious etiology for common acute lymphoblastic leukemia in childhood? (1993) (221)
- Analysis of the clinical and biological significance of lymphoid phenotypes in acute leukemia. (1981) (218)
- Structural features of the cell surface receptor for transferrin that is recognized by the monoclonal antibody OKT9. (1982) (216)
- Loops, Lineage, and Leukemia (1998) (215)
- Molecular genetics, natural history and the demise of childhood leukaemia. (1999) (214)
- Leukocyte antigen CD34 is expressed by a subset of cultured endothelial cells and on endothelial abluminal microprocesses in the tumor stroma. (1990) (209)
- Elicitation of Selective T and B Lymphocyte Responses by Cell Surface Binding Ligands (1972) (209)
- Receptors and Recognition (1978) (204)
- Developmentally regulated rearrangement and expression of genes encoding the T cell receptor-T3 complex (1986) (199)
- Association of the human type C retrovirus with a subset of adult T-cell cancers. (1983) (197)
- Identification of a membrane glycoprotein associated with haemopoietic progenitor cells. (1985) (195)
- The gene encoding the stem cell antigen, CD34, is conserved in mouse and expressed in haemopoietic progenitor cell lines, brain, and embryonic fibroblasts. (1991) (191)
- The stem cell antigen CD34 functions as a regulator of hemopoietic cell adhesion. (1995) (190)
- Phenotypic heterogeneity and cellular origins of T cell malignancies. (1981) (188)
- Childhood leukaemia (2002) (187)
- Acid Esterase in Human Lymphoid Cells and Leukaemic Blasts: a Marker for T Lymphocytes (1977) (184)
- T. and B. Lymphocytes: Origins, Properties and Roles in Immune Responses (1973) (182)
- CORRELATION OF TRANSFERRIN RECEPTOR EXPRESSION WITH HISTOLOGICAL CLASS AND OUTCOME IN NON-HODGKIN LYMPHOMA (1983) (181)
- Specific JAK2 mutation (JAK2R683) and multiple gene deletions in Down syndrome acute lymphoblastic leukemia. (2009) (179)
- Role of the TEL-AML1 fusion gene in the molecular pathogenesis of childhood acute lymphoblastic leukaemia (2004) (175)
- Cell surface markers for human T and B lymphocytes (1974) (174)
- Darwinian medicine: a case for cancer (2007) (172)
- CD34 expression is regulated reciprocally with adhesion molecules in vascular endothelial cells in vitro. (1993) (171)
- Expression of an antigen associated with acute lymphoblastic leukemia in human leukemia-lymphoma cell lines. (1978) (166)
- Mechanisms of clonal evolution in childhood acute lymphoblastic leukemia (2015) (164)
- Lymphocyte activation. II. discriminating stimulation of lymphocyte subpopulations by phytomitogens and heterologous antilymphocyte sera. (1972) (163)
- Activation of the beta-globin locus control region precedes commitment to the erythroid lineage. (1992) (163)
- In utero origins of childhood leukaemia. (2005) (162)
- Antiphospholipid antibodies and thrombosis (1999) (161)
- The transferrin receptor (1982) (154)
- Terminal Transferase Enzyme Assay and Immunological Membrane Markers in the Diagnosis of Leukaemia: a Multiparameter Analysis of 300 Cases (1980) (154)
- Antiphospholipid antibodies and thrombosis (1999) (153)
- The Histone Deacetylase 9 Gene Encodes Multiple Protein Isoforms* (2003) (150)
- A monoclonal antibody (WT1) for detecting leukemias of T-cell precursors (T-ALL). (1983) (148)
- Day care in infancy and risk of childhood acute lymphoblastic leukaemia: findings from UK case-control study (2005) (146)
- Blast Crisis of Chronic Myeloid Leukaemia (CML): II. CELL SURFACE MARKER ANALYSIS OF ‘LYMPHOID’AND MYELOID CASES (1976) (146)
- Variation at 10p12.2 and 10p14 influences risk of childhood B-cell acute lymphoblastic leukemia and phenotype. (2013) (144)
- Ligand-induced redistribution of lymphocyte membrane ganglioside GM1 (1975) (144)
- Cancer stem cells: back to Darwin? (2010) (139)
- Relation of “lymphoid” phenotype and response to chemotherapy incorporating vincristine‐prednisolone in the acute phase of Ph1 positive leukemia (1979) (139)
- TARGET CELL IN CHRONIC MYELOID LEUKÆMIA AND ITS RELATIONSHIP TO ACUTE LYMPHOID LEUKÆMIA (1976) (139)
- Acute lymphoblastic leukaemia associated antigen. IV. Expression on non-leukaemic 'lymphoid' cells. (1980) (139)
- The United Kingdom Childhood Cancer Study: objectives, materials and methods (2000) (138)
- TERMINAL DEOXYNUCLEOTIDYL-TRANSFERASE LEVELS AND MEMBRANE PHENOTYPES IN DIAGNOSIS OF ACUTE LEUKÆMIA (1977) (138)
- bcr rearrangement and translocation of the c-abl oncogene in Philadelphia positive acute lymphoblastic leukemia (1986) (138)
- Regulation of the myeloperoxidase enhancer binding proteins Pu1, C-EBP alpha, -beta, and -delta during granulocyte-lineage specification. (1996) (137)
- A non-T, non-B human leukemia cell line (NALM-1): establishment of the cell line and presence of leukemia-associated antigens. (1977) (136)
- Recruitment of the nuclear receptor corepressor N-CoR by the TEL moiety of the childhood leukemia-associated TEL-AML1 oncoprotein. (2000) (136)
- Childhood acute lymphoblastic leukemia and infections in the first year of life: a report from the United Kingdom Childhood Cancer Study. (2006) (133)
- Studies on antigen-binding cells. I. The origin of reactive cells. (1970) (133)
- HYPOTHYROIDISM AS A CAUSE OF ACQUIRED VON WDLLEBRAND'S DISEASE (1987) (131)
- Verification of the susceptibility loci on 7p12.2, 10q21.2, and 14q11.2 in precursor B-cell acute lymphoblastic leukemia of childhood. (2010) (129)
- Prenatal diagnosis from maternal blood: simultaneous immunophenotyping and FISH of fetal nucleated erythrocytes isolated by negative magnetic cell sorting. (1993) (128)
- Molecular genetics, natural history and the demise of childhood leukaemia. (1999) (127)
- Modeling first-hit functions of the t(12;21) TEL-AML1 translocation in mice. (2004) (126)
- Infant leukaemia biology, aetiology and treatment. (1996) (125)
- Expression of human T and B lymphocyte cell-surface markers on leukaemic cells. (1974) (122)
- The TEL-AML1 leukemia fusion gene dysregulates the TGF-beta pathway in early B lineage progenitor cells. (2009) (119)
- Origins of "late" relapse in childhood acute lymphoblastic leukemia with TEL-AML1 fusion genes. (2001) (118)
- Blocking of the Lymphocyte Receptor Site for Cell Mediated Hypersensitivity and Transplantation Reactions by Anti-light Chain Sera (1969) (118)
- Effect of Bursectomy and Thymectomy on the Responses of Chicken Peripheral Blood Lymphocytes to Phytohaemagglutinin (1968) (118)
- Molecular features of CD34: a hemopoietic progenitor cell-associated molecule. (1992) (113)
- Single-cell mutational profiling and clonal phylogeny in cancer (2013) (113)
- Lymphocyte activation. 3. Binding sites for phytomitogens on lymphocyte subpopulations. (1972) (111)
- Pre-natal origins of childhood leukemia. (2003) (110)
- Geographical distribution of acute lymphoblastic leukaemia subtypes: second report of the collaborative group study. (1993) (110)
- “Target” cells, cellular phenotypes, and lineage fidelity in human leukaemia (1982) (108)
- Clustering of childhood leukaemia in Hong Kong: association with the childhood peak and common acute lymphoblastic leukaemia and with population mixing. (1997) (108)
- Enumeration of Absolute Numbers of T and B Lymphocytes in Human Blood (1974) (107)
- Multiparameter studies in lymphoid leukemias. (1979) (105)
- Infant acute leukemias show the same biased distribution of ALL1 gene breaks as topoisomerase II related secondary acute leukemias. (1997) (105)
- ts BCR-ABL kinase activation confers increased resistance to genotoxic damage via cell cycle block. (1996) (102)
- Cancer: The Evolutionary Legacy (2000) (101)
- Functional Analysis of Murine and Human B Lymphocyte Subsets (1975) (101)
- Immunoglobulin gene organisation and expression in haemopoietic stem cell leukaemia. (1983) (100)
- Defining the oncogenic function of the TEL/AML1 (ETV6/RUNX1) fusion protein in a mouse model (2005) (100)
- Divergent molecular phenotypes of KG1 and KG1a myeloid cell lines. (1986) (98)
- Modulation of T leukaemic cell phenotype with phorbol ester (1982) (98)
- Prenatal origin of hyperdiploid acute lymphoblastic leukemia in identical twins (2003) (98)
- Clonal origins of relapse in ETV6-RUNX1 acute lymphoblastic leukemia. (2009) (98)
- Stem cell origins of leukaemia and curability. (1993) (98)
- Cell sorter analysis of leukaemia-associated antigens on human myeloid precursors (1978) (96)
- Monoclonal origin of concordant T-cell malignancy in identical twins. (1997) (96)
- “Ia‐like” antigens on human T cells (1979) (95)
- Receptor for transferrin may be a "target" structure for natural killer cells. (1983) (95)
- Membrane marker and cell separation studies in Ph1-positive leukemia. (1978) (95)
- Expression of hexosaminidase isoenzymes in childhood leukemia. (1978) (94)
- Molecular tracking of leukemogenesis in a triplet pregnancy. (2001) (93)
- A monoclonal antibody identifying a cell surface antigen shared by common acute lymphoblastic leukemias and B lineage cells. (1980) (92)
- Absence of p53 permits propagation of mutant cells following genotoxic damage (1997) (92)
- Structure and possible mechanisms of TEL-AML1 gene fusions in childhood acute lymphoblastic leukemia. (1999) (91)
- Terminal deoxynucleotidyl transferase in acute myeloid leukaemia. (1983) (90)
- Collaborative group study of the epidemiology of acute lymphoblastic leukaemia subtypes: background and first report. (1985) (90)
- Enforced expression of MLL-AF4 fusion in cord blood CD34+ cells enhances the hematopoietic repopulating cell function and clonogenic potential but is not sufficient to initiate leukemia. (2011) (90)
- Acquisition of genome-wide copy number alterations in monozygotic twins with acute lymphoblastic leukemia. (2010) (89)
- Leukemia-associated antigens in man. (1975) (88)
- Monoclonal antiglycophorin as a probe for erythroleukemias. (1983) (88)
- Acute lymphoblastic leukaemia (ALL) associated antigen—I. Expression in different haematopoietic malignancies (1978) (87)
- Processed pseudogenes acquired somatically during cancer development (2014) (87)
- Blast Crisis of Chronic Myeloid Leukaemia (CML): I. PRESENTATION SIMULATING ACUTE LYMPHOID LEUKAEMIA (ALL) (1976) (86)
- Differentiation Linked Expression of p28,33 (Ia‐like) Structures on Human Leukaemic Cells (1977) (85)
- Acute lymphoblastic leukaemia associated antigen. III ALterations in expression during treatment and in relapse. (1980) (85)
- Epstein-Barr virus binding sites on lymphocyte subpopulations and the origin of lymphoblasts in cultured lymphoid cell lines and in the blood of patients with infectious mononucleosis (1975) (85)
- Antigenic and enzymatic phenotypes of the pre-B subclass of acute lymphoblastic leukaemia. (1979) (84)
- Modeling the evolution of ETV6-RUNX1-induced B-cell precursor acute lymphoblastic leukemia in mice. (2011) (83)
- Structural and partial amino acid sequence analysis of the human hemopoietic progenitor cell antigen CD34. (1988) (83)
- A natural history for pediatric acute leukemia. (1993) (83)
- Comparison of the levels of inositol metabolites in transformed haemopoietic cells and their normal counterparts. (1993) (82)
- Candidate leukaemia-specific antigen in man (1975) (82)
- Expression of the CD 34 Gene in Vascular Endothelial Cells (2003) (81)
- Identification of preleukemic precursors of hyperdiploid acute lymphoblastic leukemia in cord blood (2004) (81)
- The hemopoietic stem cell antigen, CD34, is encoded by a gene located on chromosome 1. (1989) (79)
- "Pre-B" phenotypes in blast crisis of Ph1 positive CML: evidence for a pluripotential stem cell "target". (1979) (78)
- International Union of Immunological Societies (IUIS), report-July 1974: Identification, enumeration and isolation of B and T lymphocytes from human peripheral blood (1975) (77)
- The Aplastic Presentation of Childhood Leukaemia: a Feature of Common‐ALL (1981) (76)
- Genetic susceptibility to childhood common acute lymphoblastic leukaemia is associated with polymorphic peptide-binding pocket profiles in HLA-DPB1*0201. (2002) (76)
- Lymphocyte activation. V. Quantitation of the proliferative responses to mitogens using defined T and B cell populations. (1973) (76)
- Treatment of acute lymphoblastic leukaemia in adults (1986) (76)
- The association of a distinctive allele of NAD(P)H:quinone oxidoreductase with pediatric acute lymphoblastic leukemias with MLL fusion genes in Japan. (2005) (76)
- TEL Deletion Analysis Supports a Novel View of Relapse in Childhood Acute Lymphoblastic Leukemia (2004) (75)
- Characterisation of stroma‐dependent blast colony‐forming cells in human marrow (1987) (75)
- The cellular content of non Hodgkin lymphomas: a comprehensive analysis using monoclonal antibodies and other surface marker techniques. (1983) (74)
- Human Thy-1: Expression on the cell surface of neuronal and and glial cells (1982) (73)
- Acute lymphoblastic leukaemia associated antigen—II. Isolation and partial characterisation (1978) (73)
- Hemopoietic progenitor cell binding to the stromal microenvironment in vitro. (1990) (72)
- The inhibition of cell aggregation by a pure serum protein. (1965) (71)
- Murine pluripotential stem cells lack Ia antigen (1977) (71)
- Abelson virus-transformed haematopoietic cell lines with pre-B-cell characteristics (1979) (71)
- Interleukin 7-dependent B lymphocyte precursor cells are ultrasensitive to apoptosis (1994) (69)
- Cancer causation: the Darwinian downside of past success? (2002) (69)
- Leukaemia of platelet precursors: diverse features in four cases (1982) (69)
- Monoclonal antibodies defining markers with apparent selectivity for particular haemopoietic cell types may also detect antigens on cells of neural crest origin. (1982) (69)
- Membrane phenotyping: diagnosis, monitoring and classification of acute 'lymphoid' leukaemias. (1977) (69)
- bcr rearrangement and translocation of the c-abl oncogene in Philadelphia positive acute lymphoblastic leukemia. (1986) (68)
- Comparative analysis of membrane phenotypes in acute lymphoid leukemia and in lymphoid blast crisis of chronic myeloid leukaemia (1977) (68)
- Antibodies to membranes of endothelial cells and fibroblasts in scleroderma (1996) (68)
- The biochemical characterization of a cell surface antigen associated with acute lymphoblastic leukemia and lymphocyte precursors. (1981) (68)
- Is telomerase activity in cancer due to selection of stem cells and differentiation arrest? (1996) (67)
- Cancer stem cells as ‘units of selection’ (2012) (67)
- Antibody-dependent cellular cytotoxicity of vascular endothelium: characterization and pathogenic associations in systemic sclerosis. (1989) (67)
- Genetic and Functional Diversity of Propagating Cells in Glioblastoma (2014) (66)
- Immunoglobulin Determinants on the Surface of Antigen Binding T- and B-Lymphocytes in Mice (1971) (66)
- Leukaemia 'firsts' in cancer research and treatment (2016) (66)
- Establishment and characterization of a new leukaemic T‐cell line (Peer) with an unusual phenotype (1980) (65)
- Receptors and Recognition: Series A (1978) (65)
- ACUTE LEUKAEMIA WITH MIXED LYMPHOID AND MYELOID PHENOTYPE (1984) (65)
- NOTCH1 mutation can be an early, prenatal genetic event in T-ALL. (2008) (64)
- Microclustering of TEL‐AML1 translocation breakpoints in childhood acute lymphoblastic leukemia (2000) (64)
- Direct triggering of B lymphocytes by insolubilized antigen (1974) (64)
- A Monoclonal Antibody Detecting an Antigen Shared by Neural and Granulocytic Cells (1981) (63)
- Human T cell leukaemia virus associated lymphoproliferative disease: report of two cases in Nigeria. (1984) (63)
- Expression of human transferrin receptor is controlled by a gene on chromosome 3: Assignment using species specificity of a monoclonal antibody (1982) (63)
- Differential expression of HLA‐DR and DR‐linked determinants on human leukemias and lymphoid cells (1983) (62)
- Selective expression of the common acute lymphoblastic leukemia (gp 100) antigen on immature lymphoid cells and their malignant counterparts (1983) (62)
- Elevated von Willebrand factor antigen in systemic sclerosis: relationship to visceral disease. (1988) (62)
- Anticardiolipin antibodies in systemic sclerosis: immunological and clinical associations. (1988) (62)
- Studies on antigen-binding cells. II. Relationship to antigen-sensitive cells. (1970) (61)
- Selective stimulation of IgM synthesis in mouse B lymphocytes by pokeweed mitogen. (1972) (60)
- Single cell analysis of clonal architecture in acute myeloid leukaemia (2018) (60)
- Exploitation of monoclonal antibodies: a "who's who" of haemopoietic malignancy. (1981) (60)
- Rearrangement of immunoglobulin heavy chain genes in human T leukaemic cells shows preferential utilization of the D segment (DQ52) nearest to the J region. (1986) (60)
- The development of antiphospholipid antibodies in haemophilia is linked to infection with hepatitis C (1994) (60)
- Clonal evolution in myeloma: the impact of maintenance lenalidomide and depth of response on the genetics and sub-clonal structure of relapsed disease in uniformly treated newly diagnosed patients (2019) (59)
- Simultaneous genotypic and immunophenotypic analysis of interphase cells using dual-color fluorescence: a demonstration of lineage involvement in polycythemia vera. (1992) (59)
- Biological Effects of Anti‐Immunoglobulins (1970) (58)
- Allergy and risk of childhood leukaemia: Results from the UKCCS (2007) (58)
- A genome-wide association study identifies risk loci for childhood acute lymphoblastic leukemia at 10q26.13 and 12q23.1 (2016) (58)
- IMMUNOLOGICAL ANALYSIS OF HUMAN MICROGLIA: LACK OF MONOCYTIC AND LYMPHOID MEMBRANE DIFFERENTIATION ANTIGENS (1979) (58)
- Is the timing of exposure to infection a major determinant of acute lymphoblastic leukaemia in Hong Kong? (2002) (58)
- Expression of burkitt lymphoma‐associated antigen (defined by the monoclonal antibody 38.13) on both normal and malignant germinal‐centre B cells (1985) (57)
- Expression of the OKT monoclonal antibody defined antigenic determinants in malignancy. (1981) (57)
- The effect of phytohaemagglutinin and other lymphocyte mitogens on immunoglobulin synthesis by human peripheral blood lymphocytes in vitro. (1968) (56)
- Isolation and characterization of a human T lymphocyte-associated glycoprotein (gp40). (1984) (56)
- Darwin and evolutionary tales in leukemia. The Ham-Wasserman Lecture. (2009) (56)
- Restricted oncogenicity of BCR/ABL p190 in transgenic mice. (1992) (56)
- Was skin cancer a selective force for black pigmentation in early hominin evolution? (2014) (56)
- Developmental origins and impact of BCR-ABL1 fusion and IKZF1 deletions in monozygotic twins with Ph+ acute lymphoblastic leukemia. (2011) (56)
- ETV6-RUNX1 promotes survival of early B lineage progenitor cells via a dysregulated erythropoietin receptor. (2011) (55)
- Protracted postnatal natural histories in childhood leukemia (2004) (55)
- The presence of HLA-DR antigens on lactating human breast epithelium and milk fat globule membranes. (1980) (55)
- Immunologically silent cancer clone transmission from mother to offspring (2009) (54)
- The silent mutational landscape of infant MLL‐AF4 pro‐B acute lymphoblastic leukemia (2013) (54)
- Molecular Pathogenesis of MLL-Associated Leukemias (2005) (54)
- IMMUNOSUPPRESSIVE POTENCY AND IN-VITRO ACTIVITY OF ANTILYMPHOCYTE GLOBULIN (1969) (53)
- A human B lymphocyte specific antigen. (1973) (53)
- Rapid intraclonal switch of lineage dominance in congenital leukaemia with a MLL gene rearrangement. (1995) (51)
- Developmental timing of mutations revealed by whole-genome sequencing of twins with acute lymphoblastic leukemia (2013) (50)
- Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia (2018) (50)
- Chromosome assignment of monoclonal antibody‐defined determinants on human leukemic cells (1983) (49)
- Maturation Linked Expression of a Myeloid Cell Surface Antigen (1978) (49)
- Ethnic composition, age and sex, together with location and standard of housing as determinants of HLTV‐I infection in an urban trinidadian community (1986) (49)
- Biochemical characterisation of leukaemia-associated antigen p24 defined by the monoclonal antibody BA-2. (1982) (49)
- Intrauterine monoclonal origin of neonatal concordant acute lymphoblastic leukemia in monozygotic twins. (1995) (48)
- Effect of anti-lymphocyte serum on responses of human peripheral-blood lymphocytes to specific and non-specific stimulants in vitro. (1967) (48)
- Terminal deoxynucleotidyl-transferase levels and membrane phenotypes in diagnosis of acute leukaemia. (1977) (48)
- Lymphocyte activation. IV. The ultrastructural pattern of the response of mouse T and B cells to mitogenic stimulation in vitro. (1973) (48)
- Specificity of anti-theta sera in cytotoxicity and functional tests on T lymphocytes. (1971) (48)
- An immunotoxin with therapeutic potential in T cell leukemia: WT1-ricin A (1984) (48)
- Human T‐cell leukaemia virus (HTLV) in the United Kingdom (1984) (47)
- IS SPONTANEOUS MUTATION THE MAJOR ‘CAUSE’ OF CHILDHOOD ACUTE LYMPHOBLASTIC LEUKAEMIA? (1986) (47)
- Characterization of HLA-DR antigens on leukaemic cells. (1982) (46)
- Clonal rearrangement and expression of the T cell receptor beta gene and involvement of the breakpoint cluster region in blast crisis of CGL. (1986) (46)
- Antigen-binding thymus-derived lymphocytes. II. Nature of the immunoglobulin determinants. (1972) (45)
- Monoclonal antibody to ganglioside gq discriminates between haemopoietic cells and infiltrating neuroblastoma tumour cells in bone marrow (1981) (45)
- A Philadelphia chromosome positive human leukaemia cell line (NALM-1) with pre-B characteristics. (1979) (44)
- The Role of theMLL Gene in Infant Leukemia (2003) (44)
- The expression of immunoglobulin determinants on the surface of antigen‐binding lymphoid cells in mice. I. An analysis of light and heavy chain restrictions on individual cells (1971) (43)
- The membrane phenotype of T-prolymphocytic leukaemia. (2009) (43)
- Common genetic variation contributes significantly to the risk of childhood B-cell precursor acute lymphoblastic leukemia (2012) (42)
- Cloning of human thymic subcapsular cortex epithelial cells with T-lymphocyte binding sites and hemopoietic growth factor activity. (1987) (42)
- Stimulation of von Willebrand factor antigen release by immunoglobulin from thrombosis prone patients with systemic lupus erythematosus and the anti-phospholipid syndrome. (1993) (42)
- A Surface Antigen Marker for Human Monocytes (1975) (41)
- Immunoglobulin heavy-chain and CD3 delta-chain gene enhancers are DNase I-hypersensitive in hemopoietic progenitor cells. (1992) (41)
- Rationale for an international consortium to study inherited genetic susceptibility to childhood acute lymphoblastic leukemia (2011) (41)
- Genome-wide homozygosity signatures and childhood acute lymphoblastic leukemia risk. (2010) (40)
- Adenosine deaminase concentrations in leukaemia and lymphoma: relation to cell phenotypes. (1981) (40)
- Evolutionary trajectories of hyperdiploid ALL in monozygotic twins (2014) (39)
- Clonal origins of ETV6-RUNX1+ acute lymphoblastic leukemia: studies in monozygotic twins (2014) (39)
- Genetic stability of human embryonic stem cells: A first-step toward the development of potential hESC-based systems for modeling childhood leukemia. (2009) (39)
- Detecting small-area similarities in the epidemiology of childhood acute lymphoblastic leukemia and diabetes mellitus, type 1: a Bayesian approach. (2005) (39)
- Plasma and platelet von Willebrand factor defects in uremia. (1989) (39)
- The small oligomerization domain of gephyrin converts MLL to an oncogene. (2004) (38)
- The putative role of transforming viruses in childhood acute lymphoblastic leukemia. (2006) (38)
- International parallels in leukaemia and diabetes epidemiology. (2004) (38)
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- Structure and function of the transferrin receptor--a possible role in the recognition of natural killer cells. (1983) (1)
- Monoclonal antibodies against b lymphocyte antigens in the characterization of leukaemic cells (1981) (1)
- Response to Jablonski and Chaplin (2014) (1)
- Inhibition of rosette formation by antisera to cell surface determinants: an approach to the antigen receptor problem. (1972) (1)
- The impact of T(h)1/T(h)2 response variations on risk of developing childhood leukaemia: A pilot study. (2005) (1)
- PARADOXICAL INCREASE IN HUMAN FACTOR VIII AFTER INFUSION OF PORCINE FACTOR VIII CONCENTRATE IN A PATIENT WITH ACQUIRED VARIANT VON WILLEBRAND'S DISEASE (1987) (1)
- The Mutational Landscape of Relapse in High Risk Myeloma Is Significantly Impacted By the Depth of Response but Not Maintenance Lenalidomide (2017) (1)
- Book Review (2001) (0)
- Imaging hypoxia in endometrial cancer: How and why should it be done? (2022) (0)
- Monozygotic Twins with Childhood ALL Demonstrate Prenatal Origin of the Philadelphia Chromosome and Post-Natal Ikaros Deletion. (2009) (0)
- Molecular Cloning and Expression of CD 34: A Haemopoietic Progenitor-Associated Cell Surface Glycoprotein (1992) (0)
- Lymphocyte antigens in systemic lupus erythematosus detected by heterologous rabbit antisera. (1979) (0)
- Rearrangement ofimmunoglobulin heavychain genesinhumanT leukaemic cells showspreferential utilization oftheD segment (DQ52) nearest totheJregion (1986) (0)
- Recurrence of TEL/AML1-positive ALL - Relapse or a new disease? (2003) (0)
- Origins of Phenotypic Diversity in Lymphoid Malignancy (2015) (0)
- Single cell genetic analysis of Trisomy12-NOTCH1 mutated chronic lymphocytic leukaemia: Hidden sub-clones (2015) (0)
- Non-cycling cells from acute myeloid leukaemia patients harbor the FLT3-ITD (FMS-like tyrosine kinase 3-internal tandem duplication) mutation and exhibit in vitro insensitivity to TKI258, a potent FLT3-directed inhibitor (2010) (0)
- Book Review:Research in Immunochemistry and Immunobiology. Volume 1. J. B. G. Kwapinski (1973) (0)
- Developmental impact of leukaemia associated fusion genes on stem cell fate. (2005) (0)
- Book Review:Contemporary Topics in Molecular Immunology. G. L. Ada (1976) (0)
- Contemporary Topics in Immunobiology: Vol. 7 (1979) (0)
- Supporting with care. (1990) (0)
- MLL Translocation in a Multipotent Progenitor Causing Acute Lymphoblastic Leukaemia - Two-Step Model of the Disease. (2006) (0)
- Abstract 2318: Genetic and functional diversity of propagating cells in glioblastoma (2015) (0)
- Spontaneous remission of chronic pure red cell aplasia after failure of immunosuppressive therapy. (2008) (0)
- Book Review:Advances in Immunology. F. J. Dixon, Henry G. Kunkel (1976) (0)
- Immunoglobulin heavy-chain and CD 3 6 chain gene enhancers are DNase I-hypersensitive in hemopoietic progenitor cells ( differendation / stem cell / hematopoiesis ) (0)
- Cystic Fibrosis heterozygosity: Darwinian bet on cancer protection? – Author's Reply (2002) (0)
- Differentiation-Linked Gene Expression in Human Leukaemia (1980) (0)
- Dear Masato, all at once (2014) (0)
- Author Correction: A causal mechanism for childhood acute lymphoblastic leukaemia (2018) (0)
- Book Review:Contemporary Topics in Immunobiology. Volume 2. A. J. S. Davies, R. L. Carter (1974) (0)
- Membrane-Associated Antigens of Lymphoid Cells. II (1971) (0)
- Acquired Genetic Abnormalities in Acute Lymphoblastic Leukaemia in Patients with Down Syndrome. (2007) (0)
- Abstract 4884: Focal 22q11.22 deletions combined withIKZF1alterations are associated with worse clinical outcome in acute lymphoblastic leukemia (2017) (0)
- How to Win the Nobel Prize: An Unexpected Life in Science (review) (2005) (0)
- Nothing in cancer makes sense except… (2018) (0)
- Oligoclonal Origin Of Functionally Distinct Leukemic Stem Cells In Infant Acute Lymphoblastic Leukemia (2010) (0)
- Antigen recognition mechanisms. (1972) (0)
- The use of a HUVEC cDNA library to investigate the specificity of anti-endothelial cell antibodies in primary APS (1997) (0)
- TRANSFUSION INDUCED ATLL (1999) (0)
- Application of anti-ALL serum and other cell markers for leukaemia diagnosis and analysis of human stem cells. (1978) (0)
- Author Correction: Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia (2019) (0)
- The Impact of Maintenance Lenalidomide and Depth of Response on the Mutational Status of the Myeloma Clone from Presentation to Relapse (2017) (0)
- How Can We Thwart the Evolutionary Resilience of Cancer (2016) (0)
- Mechanisms of Clonal Evolution of Pre-Leukemic Clones in Childhood Pre-B Acute Lymphoblastic Leukemia (2014) (0)
- Book Review:Mitogens in Immunobiology. Joost J. Oppenheim, David L. Rosenstreich (1977) (0)
- ETV6-RUNX1 (TEL-AML1) Deregulates the Erythropoietin Receptor (EPOR) and Promotes Cell Survival. (2010) (0)
- The Etiology of Pediatric Leukemia (1995) (0)
- The Sub-Clonal Complexity of STIL-TAL1 T-ALL (2014) (0)
- ACUTE LYMPHOBLASTIC LEUKAEMIA: CORRELATION OF CELL ‘MEMBRANE MARKERS’ WITH CLINICAL FEATURES AND WITH PROGNOSIS (1978) (0)
- Phenotypes of Interleukin-3-Dependent Progenitor Cells (2003) (0)
- TEL-AML1 CONFERRED A SELECTIVE ADVANTAGE ON PRE-LEUKEMIC STEM CELL THROUGH TGFBETA PATHWAY ALTERATION (2008) (0)
- Genomics Cytoskeletal Regulatory Gene Expression and Migratory Properties of B-cell Progenitors Are Affected by the ETV 6 – RUNX 1 Rearrangement (2014) (0)
- Evolutionary Trajectory of Hyperdiploid ALL: Insights From Monozygotic Twins (2010) (0)
- TEL-AML1 Affects the Regulation of Cytoskeleton and Causes Alteration In Cellular Adhesive and Migratory Properties In An In Vitro Model of Pre-Leukemia. (2010) (0)
- Problems in Differentiation Pathways and Cellular Targets for Leukemogens Group Report (1985) (0)
- Exposure to Inflammatory Immune Responses As Driver of Clonal Evolution in Childhood Acute Lymphoblastic Leukemia (2015) (0)
- Genetic variation in Th1/Th2 cytokines and the risk of developing childhood leukaemia (2006) (0)
- acute lymphoblastic leukaemia + in monozygotic twins with Ph deletions IKZF1 fusion and BCR-ABL1 Developmental origins and impact of (2012) (0)
- Supplementary file 5. (2014) (0)
- Expression and Characterization of Leucocyte Antigens (1984) (0)
- early hominin evolution? Was skin cancer a selective force for black pigmentation in (2014) (0)
- Complexity of Clonal Architecture in Childhood Acute Lymphoblastic Leukaemia (2009) (0)
- Knowledge Acquisition for Expert Systems: Experience in Leukaemia Diagnosis (1985) (0)
- Activation of myeloid-specific genes in multipotential stem cells (1996) (0)
- Book Review:Immunology. An Introduction to Molecular and Cellular Principles of the Immune Responses. Herman N. Eisen (1975) (0)
- CLONAL ORIGINS OF HIGH-HYPERDIPLOID ACUTE LYMPHOBLASTIC LEUKEMIA (2015) (0)
- The use of high gradient magnetic separation for the preparation of leucocyte- and platelet-free red cell suspensions (2016) (0)
- Involvement of the D segment (DQ52) nearest to the JH region in immunoglobulin gene rearrangements of lymphoid-cell precursors. (1987) (0)
- Adhesive functions of the CD34 molecule on haemopoietic progenitor cells (1996) (0)
- Book Review:Contemporary Topics in Molecular Immunology. Volume 2. R. A. Reisfeld, W. J. Mandy (1974) (0)
- A causal mechanism for childhood acute lymphoblastic leukaemia (2018) (0)
- Distinctive Genotypes In Infants With T-Cell Acute Lymphoblastic Leukemia (T-ALL) (2013) (0)
- Anticardiolipin antibodies insystemic sclerosis: immunological andclinical associations (1988) (0)
- Author Correction: Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia (2019) (0)
- Sub-Clonal Genetic Heterogeneity in BCR-ABL1 Positive Acute Lymphoblastic Leukaemia (2011) (0)
- Phenotypic diversity of T cell leukemias. (1982) (0)
- Supplementary file 6. (2014) (0)
- Copernican cancer Laurent Schwartz Cancer: Between Glyco (2005) (0)
- Brief report Verification of the susceptibility loci on 7p12.2, 10q21.2, and 14q11.2 in precursor B-cell acute lymphoblastic leukemia of childhood (2010) (0)
- Book Review:Contemporary Topics in Immunobiology. Volume 1. M. G. Hanna, Jr. (1973) (0)
- Abstracts of Free Communications Presented at the Twenty‐First Annual General Meeting of the British Society for Haematology, Oxford, 27–29 March 1980 Murine CFU‐s and Haematopoietic Stem Cells (1980) (0)
- Janet Rowley (1925–2013) (2014) (0)
- Down syndrome acute lymphoblastic leukemia R 683 ) and multiple gene deletions in JAK 2 mutation ( JAK 2 Specific (2009) (0)
- Disease should be targeted from all angles (2000) (0)
- Defense and Recognition IIA (Cellular Aspects). International Review of Biochemistry, Volume 22.E. S. LennoxDefense and Recognition IIB (Structural Aspects). International Review of Biochemistry, Volume 23.E. S. Lennox (1980) (0)
- Book Review:Current Topics in Microbiology and Immunology. Ergebnisse der Mikrobiologie und Immunitatsforschung. W. Arber (1975) (0)
- Membrane Glycoproteins of Leukaemic Cells (1982) (0)
- Frontiers in Cancer Research (2016) (0)
- INHIBITION OF ANTIGEN-INDUCED LYMPHOCYTE TRANSFORMATION BY ANTI-IMMUNOGLOBULIN LIGHT-CHAIN SERA (1971) (0)
- CHARACTERIZATION OF BLAST CELLS BY ULTRASTRUCTURAL CYTO-CHEMISTRY AND MONOCLONAL-ANTIBODIES (1983) (0)
- Stem cells, haemopoiesis, and leukaemia. (2005) (0)
- Exploiting the molecular phenotypes of leukemic cells: diagnosis, etiology, and treatment (1992) (0)
- Cancer: Between Glycolysis and Physical Constraint, Laurent Schwartz. Springer (2004), Pp 168. £23·00., ISBN: 3-54020-496-2 (2005) (0)
- Immunology of Receptors. B. Cinader (1978) (0)
- Book Review:Principles of Immunology. Noel R. Rose, Felix Milgrom, Carel J. van Oss (1975) (0)
- ATPS-93CHEMO-NAÏVE GLIOBLASTOMA PATIENTS CONTAIN GENETICALLY HETEROGENEOUS SUB-CLONES CAPABLE OF TUMOUR PROPAGATION AND SPATIALLY HETEROGENEOUS DRUG-RESISTANT CELL POPULATIONS (2015) (0)
- Introduction: signals, receptors and repertoire in haemopoietic differentiation. (1981) (0)
- Dengli Hong Childhood Leukemia-Associated TEL-AML 1 Initiating and Cancer-Propagating Cells in (0)
- Cooperation Between Aid and the Rag1/Rag2 V(D)J Recombinase Drives Clonal Evolution of Childhood Acute Lymphoblastic Leukemia (2012) (0)
- Cloning of human thymic subcapsular cortex epithelial cells by SV40 ori-transfection. (1987) (0)
- Clonal Evolution and Sub-Clonal Architecture In Paediatric T-Cell Acute Lymphoblastic Leukaemia (T-ALL) (2013) (0)
- t-cell production of interleukin-8 (cxcl8) is enriched in recent thymic emigrants : 559 (2014) (0)
- Naked beauties (1985) (0)
- Genetics of Teenage and Young Adult Acute Lymphoblastic T-Cell Leukaemia. (2012) (0)
- Drug Discovery Today : Disease Models (2008) (0)
- Godwits and blast crises: In memory of David Galton (2007) (0)
- Immunobiology. Current Knowledge of Basic Concepts in Immunology and Their Clinical Applications.Robert A. Good , David W. Fisher (1972) (0)
- OP14GENETIC AND FUNCTIONAL DIVERSITY OF PROPAGATING CELLS IN GLIOBLASTOMA (2015) (0)
- Prenatal exposures and childhood cancer. (2006) (0)
- Letter: Antigenic correlations between brain and thymus. (1974) (0)
- Request for leukaemic samples from twins. (1995) (0)
- The Tyrosine Kinase Inhibitor TK258 Differentially Targets Proliferating Human Hematopoietic Progenitor Cells but Does Not Eliminate the Quiescent Fraction. (2007) (0)
- CB-18INTERROGATION OF SUB-CLONAL GENETIC DIVERSITY OF HUMAN GBM REVEALS GENETIC HETEROGENEITY IN TUMOUR-PROPAGATING CELLS, WHICH DISPLAY VARIABLE COMPETITIVE CAPACITY FOR TUMOUR PROPAGATION IN VIVO (2014) (0)
- Book Review:The Variation and Adaptive Expression of Antibodies. George P. Smith (1975) (0)
- Susceptibility to paediatric B-cell precursor acute lymphoblastic leukemia is associated with polymorphic HLA-DPB1 peptide-binding supertypes (2006) (0)
- Book Review:Advances in Immunology. Volume 17. F. J. Dixon, Henry G. Kunkel (1975) (0)
- Deletion Analysis Supports a Novel View of Relapse in Childhood Acute Lymphoblastic Leukemia (2004) (0)
- Book Reviews (2008) (0)
- Book Review:Antigens, Lymphoid Cells and the Immune Response. G. J. V. Nossal, G. L. Ada (1972) (0)
- 367 A darwinian eye view of cancer (2003) (0)
- Diagnostic use of an antiserum made against acute lymphoid leukemia associated antigen. (1978) (0)
- Review: Concepts of B Lymphocyte Activation: Transplantation Reviews (1976) (0)
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