Meritxell Huch
#88,912
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Meritxell Huchbiology Degrees
Biology
#4603
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#6843
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Developmental Biology
#89
World Rank
#95
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Biology
Meritxell Huch's Degrees
- PhD Stem Cell Biology University of Barcelona
- Bachelors Biotechnology University of Barcelona
Why Is Meritxell Huch Influential?
(Suggest an Edit or Addition)According to Wikipedia, Meritxell Huch is a stem cell biologist and director at the Max Planck Institute of Molecular Cell Biology and Genetics. Her research considers tissue regeneration and the development of tissue-specific disease models for human organs. She was awarded a European Research Council Consolidator Grant in 2023.
Meritxell Huch's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Organoid Models of Human and Mouse Ductal Pancreatic Cancer (2015) (1403)
- Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro. (2010) (1330)
- In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration (2013) (1123)
- Long-Term Culture of Genome-Stable Bipotent Stem Cells from Adult Human Liver (2015) (1022)
- Human Primary Liver Cancer -derived Organoid Cultures for disease modelling and drug screening (2017) (750)
- Tissue-specific mutation accumulation in human adult stem cells during life (2016) (645)
- Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis (2013) (553)
- In vitro expansion of human gastric epithelial stem cells and their responses to bacterial infection. (2015) (524)
- Culture and establishment of self-renewing human and mouse adult liver and pancreas 3D organoids and their genetic manipulation (2016) (445)
- Differentiated Troy + Chief Cells Act as Reserve Stem Cells to Generate All Lineages of the Stomach Epithelium (2013) (420)
- Modeling mouse and human development using organoid cultures (2015) (359)
- Genome sequencing of normal cells reveals developmental lineages and mutational processes (2014) (297)
- Controlled gene expression in primary Lgr5 organoid cultures (2011) (285)
- The hope and the hype of organoid research (2017) (255)
- Lgr5(+ve) stem/progenitor cells contribute to nephron formation during kidney development. (2012) (210)
- Disease modelling in human organoids (2019) (207)
- Diabetes Risk Gene and Wnt Effector Tcf7l2/TCF4 Controls Hepatic Response to Perinatal and Adult Metabolic Demand (2012) (202)
- Liver organoids: from basic research to therapeutic applications (2019) (163)
- Over-expression of Plk4 induces centrosome amplification, loss of primary cilia and associated tissue hyperplasia in the mouse (2015) (126)
- The balancing act of the liver: tissue regeneration versus fibrosis (2018) (123)
- Stem cells and cancer of the stomach and intestine (2010) (115)
- Expansion of Adult Human Pancreatic Tissue Yields Organoids Harboring Progenitor Cells with Endocrine Differentiation Potential (2018) (98)
- RCAN1 (DSCR1) increases neuronal susceptibility to oxidative stress: a potential pathogenic process in neurodegeneration. (2007) (95)
- Role of the putative heparan sulfate glycosaminoglycan-binding site of the adenovirus type 5 fiber shaft on liver detargeting and knob-mediated retargeting. (2006) (91)
- Structure of stem cell growth factor R-spondin 1 in complex with the ectodomain of its receptor LGR5. (2013) (84)
- Epigenetic remodelling licences adult cholangiocytes for organoid formation and liver regeneration (2019) (83)
- Transformation of intestinal stem cells into gastric stem cells on loss of transcription factor Cdx2 (2014) (82)
- Building consensus on definition and nomenclature of hepatic, pancreatic, and biliary organoids. (2021) (78)
- Mouse Model of Alagille Syndrome and Mechanisms of Jagged1 Missense Mutations (2017) (76)
- Lgr5(+) liver stem cells, hepatic organoids and regenerative medicine. (2013) (75)
- Long-Term Adult Feline Liver Organoid Cultures for Disease Modeling of Hepatic Steatosis (2017) (72)
- Disease Modeling and Gene Therapy of Copper Storage Disease in Canine Hepatic Organoids (2015) (69)
- Organoids from adult liver and pancreas: Stem cell biology and biomedical utility. (2016) (58)
- Multi-site Neurogenin3 Phosphorylation Controls Pancreatic Endocrine Differentiation (2017) (58)
- Liver regeneration and inflammation: from fundamental science to clinical applications (2021) (55)
- Long-term expansion, genomic stability and in vivo safety of adult human pancreas organoids (2020) (52)
- Generation and characterization of rat liver stem cell lines and their engraftment in a rat model of liver failure (2016) (49)
- Lgr5+ stem and progenitor cells reside at the apex of a heterogeneous embryonic hepatoblast pool (2019) (44)
- The plastic cellular states of liver cells: Are EpCAM and Lgr5 fit for purpose? (2016) (42)
- Urokinase-type plasminogen activator receptor transcriptionally controlled adenoviruses eradicate pancreatic tumors and liver metastasis in mouse models. (2009) (37)
- Defining Lineage Potential and Fate Behavior of Precursors during Pancreas Development (2018) (30)
- Long-term live imaging and multiscale analysis identify heterogeneity and core principles of epithelial organoid morphogenesis (2021) (30)
- Liver organoids reproduce alpha-1 antitrypsin deficiency-related liver disease (2019) (29)
- Universality of clone dynamics during tissue development (2018) (28)
- The plastic liver: differentiated cells, stem cells, every cell? (2014) (28)
- Sox9 marks adult organ progenitors (2010) (28)
- Application of human liver organoids as a patient-derived primary model for HBV infection and related hepatocellular carcinoma (2021) (25)
- Tat8-TK/GCV suicide gene therapy induces pancreatic tumor regression in vivo. (2005) (22)
- Human liver organoids; a patient-derived primary model for HBV Infection and Related Hepatocellular Carcinoma (2019) (21)
- Intraductal Delivery of Adenoviruses Targets Pancreatic Tumors in Transgenic Ela-myc Mice and Orthotopic Xenografts (2013) (21)
- Keratin 7 promoter selectively targets transgene expression to normal and neoplastic pancreatic ductal cells in vitro and in vivo (2009) (18)
- Cellular plasticity in the adult liver and stomach (2016) (18)
- Dynamic cell contacts between periportal mesenchyme and ductal epithelium act as a rheostat for liver cell proliferation (2021) (18)
- Targeting the CYP2B 1/cyclophosphamide suicide system to fibroblast growth factor receptors results in a potent antitumoral response in pancreatic cancer models. (2006) (17)
- Organoids (2022) (16)
- Neurogenin3 phosphorylation controls reprogramming efficiency of pancreatic ductal organoids into endocrine cells (2018) (16)
- Dual Targeting of G9a and DNA Methyltransferase‐1 for the Treatment of Experimental Cholangiocarcinoma (2020) (14)
- Definitions for adult stem cells debated (2018) (13)
- RNF43/ZNRF3 loss predisposes to hepatocellular-carcinoma by impairing liver regeneration and altering the liver lipid metabolic ground-state (2022) (12)
- Fasting improves therapeutic response in hepatocellular carcinoma through p53-dependent metabolic synergism (2022) (12)
- Chromosomal abnormalities in hepatic cysts point to novel polycystic liver disease genes (2016) (11)
- Organoids: A new in vitro model system for biomedical science and disease modelling and promising source for cell-based transplantation. (2016) (11)
- Cancer: Tumours build their niche (2017) (11)
- Regenerative biology: The versatile and plastic liver (2015) (10)
- Organoids, Where We Stand and Where We Go. (2021) (8)
- Hepatobiliary tumor organoids for personalized medicine: a multicenter view on establishment, limitations, and future directions. (2022) (7)
- Building stomach in a dish (2015) (5)
- Fasting reverses drug-resistance in hepatocellular carcinoma through p53-dependent metabolic synergism (2021) (4)
- Voices of biotech research (2021) (3)
- Loss of RNF43/ZNRF3 predisposes to Hepatocellular carcinoma by impairing liver regeneration and altering liver fat metabolism (2020) (3)
- Lgr5+ stem/progenitor cells reside at the apex of the embryonic hepatoblast pool (2018) (2)
- Metabolic Activation of Benzo[a]pyrene by Human Tissue Organoid Cultures (2022) (1)
- Author response: Application of human liver organoids as a patient-derived primary model for HBV infection and related hepatocellular carcinoma (2021) (1)
- Long-term live imaging and multiscale analysis identify heterogeneity and core principles of epithelial organoid morphogenesis (2021) (1)
- Once upon a dish: the next frontier in engineering multicellular systems. (2022) (1)
- Organoids as tools for fundamental discovery and translation—a Keystone Symposia report (2022) (1)
- Abstract B16: Using human patient-derived organoids to identify genetic dependencies in pancreatic cancer (2016) (1)
- LifeTime and improving European healthcare through cell-based interceptive medicine (2020) (1)
- Long-term live imaging of epithelial organoids and corresponding multiscale analysis reveal high heterogeneity and identify core regulatory principles (2020) (0)
- RNF43/ZNRF3 loss predisposes to hepatocellular-carcinoma by impairing liver regeneration and altering the liver lipid metabolic ground-state (2022) (0)
- "Modeling liver diseases and generating 'biobanks' of healthy and diseased cells for use in drug screening programs should be feasible in the near future." (2013) (0)
- The proportion of periportal mesenchyme to ductal epithelial cells acts as a proliferative rheostat in liver regeneration (2020) (0)
- Publisher Correction: LifeTime and improving European healthcare through cell-based interceptive medicine (2021) (0)
- Urokinase-Type Plasminogen Activator Receptor Transcriptionally Controlled Adenoviruses Eradicate Pancreatic Tumors and Liver Metastasis in Mouse Models 1 , 2 (2009) (0)
- Human Primary Liver Cancer-derived Organoid Cultures for disease modelling 1 and drug screening 2 3 4 5 (2017) (0)
- Edinburgh Research Explorer Human primary liver cancer–derived organoid cultures for disease modeling and drug screening (2017) (0)
- Bipotent Liver Progenitors Depend on Glycolysis and Mitochondrial Pyruvate Oxidation for Stem Cell Functions (2020) (0)
- Long-term expansion, genomic stability and in vivo safety of adult human pancreas organoids (2020) (0)
- Crystal structure of R-spondin 1 (Fu1Fu2) - Holmium soak (2013) (0)
- Anniversary reflections: Inspiring discoveries and the future of the field. (2022) (0)
- Crystal structure of R-spondin 1 (Fu1Fu2) - Native (2013) (0)
- Stem cell-derived organoid models: defying the Hayflick limit (2023) (0)
- Liver stem/progenitor cells and hepatic organoids to study liver biology and disease (2016) (0)
- Title : Universality of clone dynamics during tissue development (2018) (0)
- Universality of clone dynamics during tissue development (2018) (0)
- Intraductal delivery of cytotoxic adenoviruses to the pancreas induces tumor regression in mouse models of pancreatic cancer (2012) (0)
- Definitions for adult stem cells debated (2018) (0)
- Neurogenin3 phosphorylation controls reprogramming efficiency of pancreatic ductal organoids into endocrine cells (2018) (0)
- Epigenetic remodelling licences adult cholangiocytes for organoid formation and liver regeneration (2019) (0)
- P610 Wnt AND NOTCH REGULATE PROLIFERATION, MIGRATION AND DIFFERENTIATION OF HUMAN HEPATIC PROGENITOR CELLS AND CANINE LIVER ORGANOIDS (2014) (0)
- Alpha 1 Antitrypsin Deficiency molecular mechanisms in liver organoids (2019) (0)
- Structure of the ectodomain of LGR5 in complex with R-spondin-1 ( Fu1Fu2) in P22121 crystal form (2013) (0)
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What Schools Are Affiliated With Meritxell Huch?
Meritxell Huch is affiliated with the following schools:
