Merlin Crossley
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Australian academic
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Why Is Merlin Crossley Influential?
(Suggest an Edit or Addition)According to Wikipedia, Merlin Crossley, is an Australian molecular biologist, university teacher and administrator. In 2016, he was appointed as Deputy Vice-Chancellor at the University of New South Wales. Early life and career Crossley attended Mount View Primary School, Glen Waverley, Victoria, then was awarded an entrance scholarship to Melbourne Grammar School, where he was dux. He undertook a Bachelor of Science at the University of Melbourne, as a resident of Queen's College , then a doctorate at the University of Oxford supported by a Rhodes Scholarship at Magdalen College, Oxford. He worked at Oxford, Harvard and the University of Sydney, before moving to UNSW as Dean of Science. In recognition of his service on the Trust of the Australian Museum a new species of butterfly bobtail squid was named in his honour - Iridoteuthis merlini - Merlin's bobtail squid.
Merlin Crossley's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- FOG, a Multitype Zinc Finger Protein, Acts as a Cofactor for Transcription Factor GATA-1 in Erythroid and Megakaryocytic Differentiation (1997) (768)
- Zinc fingers are sticking together. (1998) (449)
- Sticky fingers: zinc-fingers as protein-recognition motifs. (2007) (399)
- Modification with SUMO (2003) (349)
- Krüppel-like transcription factors: a functional family. (2008) (348)
- Cloning and characterization of mCtBP2, a co‐repressor that associates with basic Krüppel‐like factor and other mammalian transcriptional regulators (1998) (327)
- Mammalian Krüppel-like transcription factors: more than just a pretty finger. (1999) (317)
- Transcriptional cofactors of the FOG family interact with GATA proteins by means of multiple zinc fingers (1999) (275)
- Isolation and characterization of the cDNA encoding BKLF/TEF-2, a major CACCC-box-binding protein in erythroid cells and selected other cells (1996) (238)
- Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin (2016) (233)
- Self-association of the erythroid transcription factor GATA-1 mediated by its zinc finger domains (1995) (204)
- X-linked thrombocytopenia caused by a novel mutation of GATA-1. (2001) (202)
- The CtBP family: enigmatic and enzymatic transcriptional co‐repressors (2001) (187)
- Controlling the size of lipid droplets: lipid and protein factors. (2012) (173)
- Targeted Disruption of the Basic Krüppel-Like Factor Gene (Klf3) Reveals a Role in Adipogenesis (2008) (171)
- Natural regulatory mutations elevate the fetal globin gene via disruption of BCL11A or ZBTB7A binding (2018) (170)
- The C-terminal zinc finger of GATA-1 or GATA-2 is sufficient to induce megakaryocytic differentiation of an early myeloid cell line (1995) (165)
- Human Krüppel-like factor 8: a CACCC-box binding protein that associates with CtBP and represses transcription. (2000) (164)
- Recovery from hemophilia B Leyden: an androgen-responsive element in the factor IX promoter. (1992) (138)
- Mutations of ZFPM2/FOG2 gene in sporadic cases of tetralogy of Fallot (2003) (136)
- Disruption of a C/EBP binding site in the factor IX promoter is associated with haemophilia B (1990) (128)
- Eos and Pegasus, Two Members of the Ikaros Family of Proteins with Distinct DNA Binding Activities* (2000) (122)
- Protein-Protein Interaction between Fli-1 and GATA-1 Mediates Synergistic Expression of Megakaryocyte-Specific Genes through Cooperative DNA Binding (2003) (121)
- Regulation of the erythroid Kruppel-like factor (EKLF) gene promoter by the erythroid transcription factor GATA-1. (1994) (121)
- Phosphorylation of the erythroid transcription factor GATA-1. (1994) (118)
- A Network of Krüppel-like Factors (Klfs) (2008) (116)
- Zinc fingers as protein recognition motifs: structural basis for the GATA-1/friend of GATA interaction. (2005) (110)
- hFOG-2, a Novel Zinc Finger Protein, Binds the Co-repressor mCtBP2 and Modulates GATA-mediated Activation* (1999) (107)
- Human KLF17 is a new member of the Sp/KLF family of transcription factors. (2006) (106)
- Key Residues Characteristic of GATA N-fingers Are Recognized By FOG* (1998) (100)
- Evi-1 Transforming and Repressor Activities Are Mediated by CtBP Co-repressor Proteins* (2001) (97)
- Erythroid Krüppel-Like Factor Directly Activates the Basic Krüppel-Like Factor Gene in Erythroid Cells (2007) (96)
- Editing the genome to introduce a beneficial naturally occurring mutation associated with increased fetal globin (2015) (96)
- Role for SUMO Modification in Facilitating Transcriptional Repression by BKLF (2005) (90)
- Protein interactions: is seeing believing? (2007) (90)
- Holding Tight: Cell Junctions and Cancer Spread. (2012) (88)
- KAI1 promoter activity is dependent on p53, junB and AP2: evidence for a possible mechanism underlying loss of KAI1 expression in cancer cells (2005) (84)
- The N-terminal Zinc Finger of the Erythroid Transcription Factor GATA-1 Binds GATC Motifs in DNA* (2001) (84)
- Multi-species, multi-transcription factor binding highlights conserved control of tissue-specific biological pathways (2014) (83)
- Specific Recognition of ZNF217 and Other Zinc Finger Proteins at a Surface Groove of C-Terminal Binding Proteins (2006) (80)
- Regulation of the β-globin locus (1993) (80)
- Basic Krüppel-like factor functions within a network of interacting haematopoietic transcription factors. (1999) (75)
- Molecular Analysis of the Interaction between the Hematopoietic Master Transcription Factors GATA-1 and PU.1* (2006) (72)
- Mechanisms Directing the Nuclear Localization of the CtBP Family Proteins (2006) (71)
- A Novel Corepressor, BCoR-L1, Represses Transcription through an Interaction with CtBP* (2007) (69)
- PU.1 and Haematopoietic Cell Fate: Dosage Matters (2011) (67)
- Wake-up Sleepy Gene: Reactivating Fetal Globin for β-Hemoglobinopathies. (2018) (67)
- A class of zinc fingers involved in protein-protein interactions biophysical characterization of CCHC fingers from fog and U-shaped. (2000) (67)
- The LIM Protein FHL3 Binds Basic Krüppel-like Factor/Krüppel-like Factor 3 and Its Co-repressor C-terminal-binding Protein 2* (2003) (66)
- Amplification of zinc finger gene 217 (ZNF217) and cancer: when good fingers go bad. (2007) (66)
- Expression of the parathyroid Ca(2+)-sensing receptor in cytotrophoblasts from human term placenta. (1998) (62)
- Engineering a protein scaffold from a PHD finger. (2003) (61)
- Activation and Repression of Interleukin-12 p40 Transcription by Erythroid Kruppel-like Factor in Macrophages* (2004) (60)
- KLF1 drives the expression of fetal hemoglobin in British HPFH. (2017) (60)
- The mammalian zinc finger transcription factor Krüppel‐like factor 3 (KLF3/BKLF) (2011) (58)
- KLF3 Regulates Muscle-Specific Gene Expression and Synergizes with Serum Response Factor on KLF Binding Sites (2010) (57)
- Role of the C-Terminal Binding Protein PXDLS Motif Binding Cleft in Protein Interactions and Transcriptional Repression (2006) (57)
- Induction of AP-2α Expression by Adenoviral Infection Involves Inactivation of the AP-2rep Transcriptional Corepressor CtBP1* (2001) (55)
- Involvement of the N-finger in the Self-association of GATA-1* (1998) (53)
- Adipokines and insulin action (2014) (52)
- The solution structure of the N-terminal zinc finger of GATA-1 reveals a specific binding face for the transcriptional co-factor FOG (1999) (52)
- Homo- and heterodimerization in transcriptional regulation. (2012) (51)
- CCHX Zinc Finger Derivatives Retain the Ability to Bind Zn(II) and Mediate Protein-DNA Interactions* (2003) (48)
- Solution structures of two CCHC zinc fingers from the FOG family protein U-shaped that mediate protein-protein interactions. (2000) (46)
- Impaired B Cell Development in the Absence of Krüppel-like Factor 3 (2011) (46)
- A mechanism for Ikaros regulation of human globin gene switching (2008) (45)
- THE ROLE OF OXALIC ACID AND BICARBONATE IN CALCIUM CYCLING BY FUNGI AND BACTERIA: SOME POSSIBLE IMPLICATIONS FOR SOIL ANIMALS (2004) (44)
- The Transactivation Domain within Cysteine/Histidine-rich Region 1 of CBP Comprises Two Novel Zinc-binding Modules* (2000) (42)
- Structural basis of simultaneous recruitment of the transcriptional regulators LMO2 and FOG1/ZFPM1 by the transcription factor GATA1 (2011) (42)
- Generation of Mice Deficient in both KLF3/BKLF and KLF8 Reveals a Genetic Interaction and a Role for These Factors in Embryonic Globin Gene Silencing (2013) (41)
- KLF1 directly activates expression of the novel fetal globin repressor ZBTB7A/LRF in erythroid cells. (2017) (40)
- The CACCC-Binding Protein KLF3/BKLF Represses a Subset of KLF1/EKLF Target Genes and Is Required for Proper Erythroid Maturation In Vivo (2012) (40)
- Chromatin modifiers in transcription and DNA repair. (2004) (38)
- Loss of Krüppel-Like Factor 3 (KLF3/BKLF) Leads to Upregulation of the Insulin-Sensitizing Factor Adipolin (FAM132A/CTRP12/C1qdc2) (2013) (38)
- New Insights into DNA Recognition by Zinc Fingers Revealed by Structural Analysis of the Oncoprotein ZNF217* (2013) (37)
- A natural regulatory mutation in the proximal promoter elevates fetal globin expression by creating a de novo GATA1 site. (2019) (37)
- Two-timing zinc finger transcription factors liaising with RNA. (2012) (36)
- A rapid method for assessing the RNA-binding potential of a protein (2012) (36)
- Identification of regulatory regions within the KAI1 promoter: a role for binding of AP1, AP2 and p53. (2003) (35)
- ZNF410 uniquely activates the NuRD component CHD4 to silence fetal hemoglobin expression (2020) (35)
- Krüppel-like factors compete for promoters and enhancers to fine-tune transcription (2017) (34)
- ENU-induced Mutation in the DNA-binding Domain of KLF3 Reveals Important Roles for KLF3 in Cardiovascular Development and Function in Mice (2013) (34)
- Pentaprobe: a comprehensive sequence for the one-step detection of DNA-binding activities. (2003) (33)
- Regions outside the DNA-binding domain are critical for proper in vivo specificity of an archetypal zinc finger transcription factor (2013) (33)
- The role of the coiled-coil motif in interactions mediated by TPD52. (2001) (32)
- Global citizen deliberation on genome editing (2020) (32)
- GATA Proteins Work Together with Friend of GATA (FOG) and C-terminal Binding Protein (CTBP) Co-regulators to Control Adipogenesis* (2010) (32)
- The Ikaros family protein Eos associates with C-terminal-binding protein corepressors. (2002) (31)
- A Classic Zinc Finger from Friend of GATA Mediates an Interaction with the Coiled-coil of Transforming Acidic Coiled-coil 3* (2004) (30)
- Programming of marginal zone B-cell fate by basic Kruppel-like factor (BKLF/KLF3). (2011) (29)
- Hemophilia B Leyden and once mysterious cis-regulatory mutations. (2014) (27)
- Transcription Factor Erythroid Krüppel-like Factor (ELKF) Is Essential for the Erythropoietin-induced Hemoglobin Production but Not for Proliferation, Viability, or Morphological Maturation* (1998) (27)
- Eosinophil function in adipose tissue is regulated by Krüppel-like factor 3 (KLF3) (2020) (26)
- A less severe form of Haemophilia B Leyden. (1990) (26)
- A CpG mutational hotspot in a ONECUT binding site accounts for the prevalent variant of hemophilia B Leyden. (2013) (25)
- Characterization of the Conserved Interaction between GATA and FOG Family Proteins* 210 (2002) (25)
- The regulation of human globin promoters by CCAAT box elements and the recruitment of NF-Y. (2017) (25)
- The Multi-zinc Finger Protein ZNF217 Contacts DNA through a Two-finger Domain* (2011) (24)
- Phosphorylation of Krüppel-like Factor 3 (KLF3/BKLF) and C-terminal Binding Protein 2 (CtBP2) by Homeodomain-interacting Protein Kinase 2 (HIPK2) Modulates KLF3 DNA Binding and Activity* (2015) (23)
- C-terminal binding protein: A metabolic sensor implicated in regulating adipogenesis. (2011) (23)
- Protein-Protein Interaction between Fli-1 and GATA-1 Mediates Synergistic Expression of Megakaryocyte-Specific Genes through Cooperative DNA Binding (2004) (23)
- Solution structure of the THAP domain from Caenorhabditis elegans C-terminal binding protein (CtBP). (2007) (23)
- A L225A substitution in the human tumour suppressor HIC1 abolishes its interaction with the corepressor CtBP (2006) (21)
- A new zinc binding fold underlines the versatility of zinc binding modules in protein evolution. (2002) (21)
- Protein–protein interactions: Analysis of a false positive GST pulldown result (2011) (21)
- Methylation of a CGATA element inhibits binding and regulation by GATA-1 (2020) (19)
- The Caenorhabditis elegans protein CTBP-1 defines a new group of THAP domain-containing CtBP corepressors. (2008) (19)
- Key challenges in bringing CRISPR-mediated somatic cell therapy into the clinic (2017) (19)
- Homeodomain-Interacting Protein Kinase (HPK-1) regulates stress responses and ageing in C. elegans (2016) (18)
- Krüppel-like Factor 3 (KLF3/BKLF) Is Required for Widespread Repression of the Inflammatory Modulator Galectin-3 (Lgals3)* (2016) (17)
- Disrupting the adult-globin promoter alleviates promoter competition and reactivates foetal-globin gene expression. (2022) (16)
- Comparative sequence analysis of mammalian factor IX promoters. (1990) (16)
- Identification of novel HPFH-like mutations by CRISPR base editing that elevate the expression of fetal hemoglobin (2022) (15)
- The C-terminal Domain of Eos Forms a High Order Complex in Solution* (2003) (15)
- DNA damage repair and transcription (2004) (15)
- Activation of γ-globin gene expression by GATA1 and NF-Y in hereditary persistence of fetal hemoglobin (2021) (13)
- Structural studies on a protein-binding zinc-finger domain of Eos reveal both similarities and differences to classical zinc fingers. (2004) (13)
- Regulation of the beta-globin locus. (1993) (13)
- Defining Eosinophil Function in Adiposity and Weight Loss (2018) (12)
- Krüppel-like factor 3 (KLF3) suppresses NF-κB–driven inflammation in mice (2020) (12)
- Repression of chimeric transcripts emanating from endogenous retrotransposons by a sequence-specific transcription factor (2014) (12)
- Differential regulation of the α-globin locus by Krüppel-like factor 3 in erythroid and non-erythroid cells (2014) (11)
- Response to Chatr-aryamontri et al.: Protein interactions: to believe or not to believe? (2008) (11)
- Structural basis for human ZBTB7A action at the fetal globin promoter (2021) (11)
- Homeodomain interacting protein kinase (HPK‐1) is required in the soma for robust germline proliferation in C. elegans (2013) (11)
- Mutations of ZFPM2/FOG2 gene in sporadic cases of tetralogy of Fallot (2003) (10)
- Directing an artificial zinc finger protein to new targets by fusion to a non-DNA-binding domain (2015) (9)
- The transcriptional repressor CTBP-1 functions in the nervous system of Caenorhabditis elegans to regulate lifespan (2014) (9)
- Assessment of the robustness of a serendipitous zinc binding fold: mutagenesis and protein grafting. (2005) (9)
- The Identification and Structure of an N-Terminal PR Domain Show that FOG1 Is a Member of the PRDM Family of Proteins (2014) (8)
- Hls5 regulated erythroid differentiation by modulating GATA-1 activity. (2008) (7)
- Hls5, a Novel Ubiquitin E3 Ligase, Modulates Levels of Sumoylated GATA-1. (2009) (7)
- SUMV-1 antagonizes the activity of synthetic multivulva genes in Caenorhabditis elegans. (2014) (6)
- Hit and Run Transcriptional Repressors Are Difficult to Catch in the Act (2019) (6)
- HIC2 controls developmental hemoglobin switching by repressing BCL11A transcription (2021) (6)
- Repression of chimeric transcripts emanating from endogenous retrotransposons by a sequence-specific transcription factor (2014) (5)
- Direct competition between DNA binding factors highlights the role of Krüppel-like Factor 1 in the erythroid/megakaryocyte switch (2017) (5)
- Co-regulator Interactions in Krüppel-like Factor Transcriptional Programs (2009) (4)
- The LRF/ZBTB7A Transcription Factor Is a BCL11A-Independent Repressor of Fetal Hemoglobin (2015) (4)
- Not the adem relations (1992) (4)
- Genome Editing of Erythroid Cell Culture Model Systems. (2018) (4)
- What is CRISPR gene editing, and how does it work? (2018) (3)
- Solution structure of the THAP domain from C. elegans C-terminal binding protein (CtBP) (2007) (3)
- Partial reprogramming of heterologous cells by defined factors to generate megakaryocyte lineage-restricted biomolecules (2018) (3)
- SOLUTION STRUCTURE OF THE N-TERMINAL ZINC FINGER OF MURINE GATA-1, NMR, 25 STRUCTURES (1999) (3)
- Specific recognition of ZNF 217 and other zinc-finger proteins at a surface 1 groove of CtBPs 2 3 (2006) (3)
- Is there a telltale RH fingerprint in zinc fingers that recognizes methylated CpG dinucleotides? (2013) (2)
- CtBP and Hematopoietic Transcriptional Regulators (2007) (2)
- Cellular Reprogramming toward the Erythroid Lineage (2011) (1)
- Transcription of the genome: don't read it all at once (2001) (1)
- Identification of a novel, erythroid BKLF promoter (2007) (1)
- Effective therapies for sickle cell disease: are we there yet? (2022) (1)
- Key challenges in bringing CRISPR-mediated somatic cell therapy into the clinic (2017) (1)
- Solution structure of the 2nd PHD domain from Mi2b with C-terminal loop replaced by corresponding loop from WSTF (2003) (1)
- (BKLF/KLF3) Programming of marginal zone B-cell fate by basic Krüppel-like factor (2012) (1)
- Eosinophil function in adipose tissue is regulated by Krüppel-like factor 3 (KLF3) (2020) (1)
- Birth of the PLuS Alliance (2019) (0)
- Basic Kruppel-like factor recruits multiple co-repressors to silence gene expression (2003) (0)
- Protocols for protein-DNA binding analysis of a zinc finger transcription factor bound to its cognate promoter (2022) (0)
- Novel insights into the role of EKLF and related factors in haemoglobin switching using EKLF null cell lines. (2003) (0)
- Solution structure of Designed Functional Finger 5 (DFF5): Designed mutant based on non-native CHANCE domain (2005) (0)
- B cell development (WS-030) Chairpersons: Daisuke Kitamura, David Gray (2010) (0)
- Non-native Solution Structure of a fragment of the CH1 domain of CBP (2002) (0)
- Solution structure of the third zinc finger domain of FOG-1 (2004) (0)
- haddock model of GATA1NF:Lmo2LIM2-Ldb1LID with FOG (2011) (0)
- Methylation of a CGATA element inhibits binding and regulation by GATA-1 (2020) (0)
- blood-2016-01-694331-1 (2016) (0)
- CTBP/BARS in ternary complex with NAD(H) and RRTGAPPAL peptide (2006) (0)
- Author response: Multi-species, multi-transcription factor binding highlights conserved control of tissue-specific biological pathways (2014) (0)
- The regulation of gene repression by BKLF (2007) (0)
- Solution structure of Minimal Mutant 1 (MM1): Multiple alanine mutant of non-native CHANCE domain (2005) (0)
- Hls5 REGULATES ERYTHROID DIFFERENTIATION BY MODULATING GATA-1 ACTIVITY Short title: Hls5 modulates GATA-1 activity (2007) (0)
- Erratum to: Repression of chimeric transcripts emanating from endogenous retrotransposons by a sequence-specific transcription factor (2016) (0)
- Solution Structure of the Third Zinc Finger from BKLF (2003) (0)
- Solution structure of Minimal Mutant 2 (MM2): Multiple alanine mutant of non-native CHANCE domain (2005) (0)
- The regulation of C-terminal Binding Protein (CtBP) by a putative chromatin modifier (2012) (0)
- SOLUTION STRUCTURE OF THE NINTH ZINC-FINGER DOMAIN OF THE U-SHAPED TRANSCRIPTION FACTOR (2000) (0)
- haddock model of GATA1NF:Lmo2LIM2-Ldb1LID (2011) (0)
- Unscrambling the genome (2003) (0)
- Erratum to: Repression of chimeric transcripts emanating from endogenous retrotransposons by a sequence-specific transcription factor (2016) (0)
- Natural regulatory mutations elevate the fetal globin gene via disruption of BCL11A or ZBTB7A binding (2018) (0)
- Solution structure of Designed Functional Finger 2 (DFF2): Designed mutant based on non-native CHANCE domain (2005) (0)
- Running title: EKLF/KLF1 and KLF3 in erythropoiesis 3 (2012) (0)
- Industrial Chemistry. Volume 1, Inorganic. Volume 2, Organic. Fifth edition (Rogers, Allen; et al.) (1932) (0)
- Fine-Tuning Erythropoiesis By Competition Between Krüppel-like Factors for Promoters and Enhancers (2016) (0)
- FUNCTIONALLY DISTINCT UTILIZATION OF CIS-REGULATORY ELEMENTS IN HEREDITARY PERSISTENCE OF FETAL HEMOGLOBIN (2019) (0)
- Genome packaging and expression (2002) (0)
- Direct competition between DNA binding factors highlights the role of Krüppel-like Factor 1 in the erythroid/megakaryocyte switch (2017) (0)
- SOLUTION STRUCTURE OF THE FIRST ZINC FINGER FROM THE DROSOPHILA U-SHAPED TRANSCRIPTION FACTOR (2000) (0)
- Solution structure of Designed Functional Finger 7 (DFF7): Designed mutant based on non-native CHANCE domain (2005) (0)
- of Krüppel-like Factor 3 Impaired B Cell Development in the Absence (2011) (0)
- 884KAI1 promoter activity is dependent on P53, junb and AP2: Evidence for a possible mechanism underlying loss of KAI1 expression in cancer cells (2005) (0)
- Erratum: Mutations of ZFPM2/FOG2 Gene in Sporadic Cases of Tetralogy of Fallot (Human Mutation (2003) 22 (372-377)) (2003) (0)
- Quinlan, K (2017) (0)
- Figure 3, [CtBP in leukemogenesis. Two models...]. (2013) (0)
- Charting a noncoding gene for γ-globin activation. (2018) (0)
- domains . factor GATA-1 mediated by its zinc finger Self-association of the erythroid transcription (1995) (0)
- Science is often an acquired taste (2012) (0)
- Election 2016: What will a re-elected Coalition government mean for key policy areas? (2016) (0)
- LETTER TO JAPANESE COLLEAGUES (1997) (0)
- The activity of FOG-1 is potentiated by its ability to contact GATA-1 through multiple zinc fingers (1999) (0)
- In grateful recognition of our Editorial Board (2016) (0)
- Acknowledgement to reviewers (2004) (0)
- Solution structure of the 2nd PHD domain from Mi2b (2003) (0)
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