Mervyn Maze
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Computer Science
Mervyn Maze's Degrees
- PhD Computer Science Stanford University
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Why Is Mervyn Maze Influential?
(Suggest an Edit or Addition)According to Wikipedia, Mervyn Maze, MD, MB ChB has been a Professor in the Departments of Anesthesia and Pain Medicine, Intensive Care at the University of California, San Francisco since 1988. He has also served as Professor and Chair at Imperial College London.
Mervyn Maze's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial. (2007) (1030)
- Effects of intravenous dexmedetomidine in humans. I. Sedation, ventilation, and metabolic rate. (1992) (823)
- Alpha‐2 Adrenoceptor Agonists: Defining the Role in Clinical Anesthesia (1991) (783)
- Effects of intravenous dexmedetomidine in humans. II. Hemodynamic changes. (1992) (762)
- The &agr;2-Adrenoceptor Agonist Dexmedetomidine Converges on an Endogenous Sleep-promoting Pathway to Exert Its Sedative Effects (2003) (740)
- Clinical Uses of ??2-Adrenergic Agonists: (2000) (578)
- The sedative component of anesthesia is mediated by GABAA receptors in an endogenous sleep pathway (2002) (557)
- Role of interleukin‐1β in postoperative cognitive dysfunction (2010) (525)
- Dexmedetomidine for prevention of delirium in elderly patients after non-cardiac surgery: a randomised, double-blind, placebo-controlled trial (2016) (500)
- Postoperative Cognitive Dysfunction after Noncardiac Surgery: A Systematic Review (2007) (498)
- Tumor necrosis factor-α triggers a cytokine cascade yielding postoperative cognitive decline (2010) (481)
- Resolving postoperative neuroinflammation and cognitive decline (2011) (460)
- Dexmedetomidine Attenuates Isoflurane-induced Neurocognitive Impairment in Neonatal Rats (2009) (418)
- Substitution of a mutant alpha2a-adrenergic receptor via "hit and run" gene targeting reveals the role of this subtype in sedative, analgesic, and anesthetic-sparing responses in vivo. (1997) (380)
- A Hypnotic Response to Dexmedetomidine, an α2 Agonist, Is Mediated in the Locus Coerüleus in Rats (1992) (367)
- Postoperative Impairment of Cognitive Function in Rats: A Possible Role for Cytokine-mediated Inflammation in the Hippocampus (2007) (361)
- Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial (2010) (359)
- Bundled Payments in Total Joint Arthroplasty: Targeting Opportunities for Quality Improvement and Cost Reduction (2014) (358)
- Clinical uses of alpha2 -adrenergic agonists. (2000) (344)
- Dexmedetomidine Injection into the Locus Ceruleus Produces Antinociception (1996) (339)
- The Pharmacokinetics and Hemodynamic Effects of Intravenous and Intramuscular Dexmedetomidine Hydrochloride in Adult Human Volunteers (1993) (310)
- Biologic Effects of Nitrous Oxide: A Mechanistic and Toxicologic Review (2008) (288)
- Xenon Mitigates Isoflurane-induced Neuronal Apoptosis in the Developing Rodent Brain (2007) (265)
- Dexmedetomidine provides cortical neuroprotection: impact on anaesthetic‐induced neuroapoptosis in the rat developing brain (2009) (264)
- Xenon and hypothermia combine to provide neuroprotection from neonatal asphyxia (2005) (258)
- Alpha 2 adrenoceptor agonists and anaesthesia. (1993) (252)
- Dexmedetomidine provides renoprotection against ischemia-reperfusion injury in mice (2011) (244)
- Neuroprotection by the alpha 2-adrenoreceptor agonist dexmedetomidine in a focal model of cerebral ischemia. (1993) (241)
- Dexmedetomidine produces its neuroprotective effect via the α2A-adrenoceptor subtype (2004) (232)
- Dexmedetomidine Diminishes Halothane Anesthetic Requirements in Rats Through a Postsynaptic Alpha2 Adrenergic Receptor (1988) (232)
- Competitive Inhibition at the Glycine Site of the N-Methyl-d-aspartate Receptor by the Anesthetics Xenon and Isoflurane: Evidence from Molecular Modeling and Electrophysiology (2007) (219)
- Xenon preconditioning protects against renal ischemic-reperfusion injury via HIF-1alpha activation. (2009) (210)
- Dexmedetomidine produces a hypnotic-anesthetic action in rats via activation of central alpha-2 adrenoceptors. (1989) (204)
- Effects of Xenon on In Vitro and In Vivo Models of Neuronal Injury (2002) (200)
- The impact of IL-1 modulation on the development of lipopolysaccharide-induced cognitive dysfunction (2010) (198)
- Microglia mediate postoperative hippocampal inflammation and cognitive decline in mice. (2017) (189)
- Hypothermia and other treatment options for neonatal encephalopathy: an executive summary of the Eunice Kennedy Shriver NICHD workshop. (2011) (186)
- A hypnotic response to dexmedetomidine, an alpha 2 agonist, is mediated in the locus coeruleus in rats. (1992) (183)
- Role of endogenous sleep‐wake and analgesic systems in anesthesia (2008) (183)
- Anesthetic and Hemodynamic Effects of the Stereoisomers of Medetomidine, an α2‐Adrenergic Agonist, in Halothane‐Anesthetized Dogs (1988) (175)
- The Neuroprotective Effect of Xenon Administration during Transient Middle Cerebral Artery Occlusion in Mice (2003) (173)
- Clinical efficacy of oral-transdermal clonidine combinations during the perioperative period. (1991) (170)
- Neuroprotective and neurotoxic properties of the 'inert' gas, xenon. (2002) (169)
- Xenon Preconditioning Reduces Brain Damage from Neonatal Asphyxia in Rats (2006) (168)
- Moderate hypothermia within 6 h of birth plus inhaled xenon versus moderate hypothermia alone after birth asphyxia (TOBY-Xe): a proof-of-concept, open-label, randomised controlled trial (2016) (167)
- Xenon Attenuates Cardiopulmonary Bypass–induced Neurologic and Neurocognitive Dysfunction in the Rat (2002) (166)
- New agents for sedation in the intensive care unit. (2001) (162)
- Tumor necrosis factor-alpha (TNF) triggers a cytokine cascade yielding postoperative cognitive decline (2010) (158)
- Cognitive decline following major surgery is associated with gliosis, &bgr;-amyloid accumulation, and &tgr; phosphorylation in old mice (2010) (157)
- Perioperative cognitive decline in the aging population. (2011) (148)
- The neuroinflammatory response of postoperative cognitive decline. (2013) (148)
- Dexmedetomidine produces its neuroprotective effect via the alpha 2A-adrenoceptor subtype. (2004) (148)
- Best Practices for Postoperative Brain Health: Recommendations From the Fifth International Perioperative Neurotoxicity Working Group (2018) (148)
- Attentional effects of noradrenaline vary with arousal level: selective activation of thalamic pulvinar in humans (2004) (147)
- A Multicenter Dose-escalation Study of the Analgesic and Adverse Effects of an Oral Cannabis Extract (Cannador) for Postoperative Pain Management (2006) (147)
- Computer-controlled Infusion of Intravenous Dexmedetomidine Hydrochloride in Adult Human Volunteers (1993) (139)
- Perioperative management of the obese surgical patient (2017) (139)
- Evaluation of high fidelity patient simulator in assessment of performance of anaesthetists. (2003) (139)
- Antinociceptive Action of Nitrous Oxide Is Mediated by Stimulation of Noradrenergic Neurons in the Brainstem and Activation of α2B Adrenoceptors (2000) (139)
- The Analgesic Potency of Dexmedetomidine Is Enhanced After Nerve Injury: A Possible Role for Peripheral alpha2-Adrenoceptors (1998) (139)
- The neuroprotective effects of xenon and helium in an in vitro model of traumatic brain injury* (2008) (133)
- Depletion of Bone Marrow–derived Macrophages Perturbs the Innate Immune Response to Surgery and Reduces Postoperative Memory Dysfunction (2013) (129)
- Molecular Mechanisms Transducing the Anesthetic, Analgesic, and Organ-protective Actions of Xenon (2006) (129)
- Anticipating and managing postoperative delirium and cognitive decline in adults (2011) (125)
- High-mobility Group Box 1 Protein Initiates Postoperative Cognitive Decline by Engaging Bone Marrow–derived Macrophages (2014) (124)
- Xenon: no stranger to anaesthesia. (2003) (122)
- Systemic inflammation enhances surgery-induced cognitive dysfunction in mice (2011) (122)
- Isoflurane and Nociception: Spinal &agr;2A Adrenoceptors Mediate Antinociception while Supraspinal &agr;1 Adrenoceptors Mediate Pronociception (2002) (119)
- The Involvement of Hypothalamic Sleep Pathways in General Anesthesia: Testing the Hypothesis Using the GABAA Receptor β3N265M Knock-In Mouse (2009) (115)
- Perturbation of Ion Channel Conductance Alters the Hypnotic Response to the α2-Adrenergic Agonist Dexmedetomidine in the Locus Coeruleus of the Rat (1994) (115)
- The analgesic action of nitrous oxide is dependent on the release of norepinephrine in the dorsal horn of the spinal cord. (1999) (115)
- Xenon augmented hypothermia reduces early lactate/N‐acetylaspartate and cell death in perinatal asphyxia (2011) (113)
- Perioperative cerebrospinal fluid and plasma inflammatory markers after orthopedic surgery (2016) (112)
- Comparative Analgesic and Mental Effects of Increasing Plasma Concentrations of Dexmedetomidine and Alfentanil in Humans (2004) (111)
- Effects of Dexmedetomidine, a Novel Imidazole Sedative‐Anesthetic Agent, on Adrenal Steroidogenesis: In Vivo and In Vitro Studies (1991) (107)
- Antinociceptive Response to Nitrous Oxide Is Mediated by Supraspinal Opiate and Spinal alpha sub 2 Adrenergic Receptors in the Rat (1996) (106)
- Alpha‐7 nicotinic acetylcholine receptor agonist treatment reduces neuroinflammation, oxidative stress, and brain injury in mice with ischemic stroke and bone fracture (2014) (103)
- Neuroprotection (and lack of neuroprotection) afforded by a series of noble gases in an in vitro model of neuronal injury (2009) (102)
- Effect of Inhaled Xenon on Cerebral White Matter Damage in Comatose Survivors of Out-of-Hospital Cardiac Arrest: A Randomized Clinical Trial. (2016) (102)
- Dexmedetomidine, acting through central alpha-2 adrenoceptors, prevents opiate-induced muscle rigidity in the rat. (1989) (100)
- Xenon Pretreatment Attenuates Anesthetic-induced Apoptosis in the Developing Brain in Comparison with Nitrous Oxide and Hypoxia (2010) (100)
- Nociceptive stimuli enhance anesthetic-induced neuroapoptosis in the rat developing brain (2012) (100)
- Preoperative medical testing in Medicare patients undergoing cataract surgery. (2015) (99)
- α2-Adrenoceptor agonists: shedding light on neuroprotection? (2005) (99)
- Dexmedetomidine prevents epinephrine-induced arrhythmias through stimulation of central alpha 2 adrenoceptors in halothane-anesthetized dogs. (1991) (99)
- Antisense technology reveals the alpha2A adrenoceptor to be the subtype mediating the hypnotic response to the highly selective agonist, dexmedetomidine, in the locus coeruleus of the rat. (1996) (98)
- Xenon: elemental anaesthesia in clinical practice. (2004) (96)
- Xenon and Sevoflurane Protect against Brain Injury in a Neonatal Asphyxia Model (2008) (95)
- Neuronal Preconditioning by Inhalational Anesthetics: Evidence for the Role of Plasmalemmal Adenosine Triphosphate–sensitive Potassium Channels (2009) (94)
- Neuroprotection and neurotoxicity in the developing brain: an update on the effects of dexmedetomidine and xenon. (2017) (93)
- Nitrous oxide produces antinociceptive response via alpha2B and/or alpha2C adrenoceptor subtypes in mice. (1999) (92)
- Sedation improves early outcome in severely septic Sprague Dawley rats (2009) (90)
- Activation of α-7 Nicotinic Acetylcholine Receptor Reduces Ischemic Stroke Injury through Reduction of Pro-Inflammatory Macrophages and Oxidative Stress (2014) (85)
- Dexmedetomidine Decreases Cerebral Blood Flow Velocity in Humans (1993) (85)
- Interleukin‐6 is both necessary and sufficient to produce perioperative neurocognitive disorder in mice (2018) (85)
- Identification of Receptor Mechanism Mediating Epinephrine‐induced Arrhythmias during Halothane Anesthesia in the Dog (1983) (85)
- α2-Adrenoceptors inhibit a nociceptive response in neonatal rat spinal cord (1991) (83)
- Methylprednisolone prevents the development of autotomy and neuropathic edema in rats, but has no effect on nociceptive thresholds (1999) (83)
- Opiate receptors in the periaqueductal gray mediate analgesic effect of nitrous oxide in rats. (1997) (83)
- The immune response of the human brain to abdominal surgery (2017) (82)
- Contribution of sedative-hypnotic agents to delirium via modulation of the sleep pathway (2010) (82)
- The α2A adrenoceptor and the sympathetic postganglionic neuron contribute to the development of neuropathic heat hyperalgesia in mice (2000) (80)
- Inhibition of adenylate cyclase in the locus coeruleus mediates the hypnotic response to an alpha 2 agonist in the rat. (1992) (79)
- Recent advances in understanding the actions and toxicity of nitrous oxide (2000) (78)
- Ventilatory effects of clonidine alone and in the presence of alfentanil, in human volunteers. (1992) (77)
- Perioperative Neurocognitive Disorder: State of the Preclinical Science. (2020) (77)
- Isoflurane and an α2-Adrenoceptor Agonist Suppress Nociceptive Neurotransmission in Neonatal Rat Spinal Cord (1991) (77)
- Synergistic Interaction Between α2-Adrenergic Agonists and Benzodiazepines in Rats (1992) (76)
- Effect of noble gases on oxygen and glucose deprived injury in human tubular kidney cells (2010) (74)
- Surgery Results in Exaggerated and Persistent Cognitive Decline in a Rat Model of the Metabolic Syndrome (2013) (74)
- Benzodiazepine Augmented &ggr;-Amino-Butyric Acid Signaling Increases Mortality From Pneumonia in Mice* (2013) (73)
- General Anesthetics Induce Apoptotic Neurodegeneration in the Neonatal Rat Spinal Cord (2008) (71)
- Asynchronous administration of xenon and hypothermia significantly reduces brain infarction in the neonatal rat. (2007) (70)
- Neurobiology of nitrous oxide-induced antinociceptive effects (2002) (69)
- Arrangement of Transmembrane Domains in Adrenergic Receptors (1996) (69)
- Dysfunction of Inflammation-Resolving Pathways Is Associated with Exaggerated Postoperative Cognitive Decline in a Rat Model of the Metabolic Syndrome (2012) (67)
- Stimulation of the α7 Nicotinic Acetylcholine Receptor Protects against Neuroinflammation after Tibia Fracture and Endotoxemia in Mice (2014) (66)
- Neuroprotective interaction produced by xenon and dexmedetomidine on in vitro and in vivo neuronal injury models (2006) (65)
- Clonidine and other alpha2 adrenergic agonists: strategies for the rational use of these novel anesthetic agents. (1988) (65)
- Sedation & immunomodulation. (2011) (64)
- Meperidine Exerts Agonist Activity at the &agr;2B-Adrenoceptor Subtype (2002) (64)
- Xenon Neuroprotection in Experimental Stroke: Interactions with Hypothermia and Intracerebral Hemorrhage (2012) (64)
- Pharmacokinetics and interaction pharmacodynamics of dexmedetomidine in humans (2000) (63)
- Xenon preconditioning confers neuroprotection regardless of gender in a mouse model of transient middle cerebral artery occlusion (2010) (61)
- Alpha2-adrenoceptor agonists. (2007) (61)
- Dexmedetomidine Enhances Analgesic Action of Nitrous Oxide: Mechanisms of Action (2004) (60)
- Dexmedetomidine: another arrow for the clinician's quiver. (2004) (59)
- Feasibility and Safety of Delivering Xenon to Patients Undergoing Coronary Artery Bypass Graft Surgery While on Cardiopulmonary Bypass: Phase I Study (2006) (59)
- Alpha 2-adrenoceptor agonists and anesthesia. (1995) (59)
- Glucocorticoid Inhibition of Neuropathic Hyperalgesia and Spinal Fos Expression (2001) (59)
- Feasibility and Cardiac Safety of Inhaled Xenon in Combination With Therapeutic Hypothermia Following Out-of-Hospital Cardiac Arrest* (2013) (58)
- Anaesthesia induced neuroprotection. (2005) (58)
- Balancing paediatric anaesthesia: preclinical insights into analgesia, hypnosis, neuroprotection, and neurotoxicity. (2008) (58)
- Preconditioning and Postinsult Therapies for Perinatal Hypoxic–Ischemic Injury at Term (2010) (57)
- Clonidine reduces halothane MAC in rats. (1987) (57)
- Xenon and Sevoflurane Provide Analgesia during Labor and Fetal Brain Protection in a Perinatal Rat Model of Hypoxia-Ischemia (2012) (57)
- alpha2-Adrenoceptor agonists: shedding light on neuroprotection? (2004) (53)
- Noble Gas Xenon Is a Novel Adenosine Triphosphate-sensitive Potassium Channel Opener (2010) (52)
- Central α1-Adrenoceptor Stimulation Functionally Antagonizes the Hypnotic Response to Dexmedetomidine, an α2-Adrenoceptor Agonist (1991) (51)
- Impact of Dexmedetomidine on Long-term Outcomes After Noncardiac Surgery in Elderly: 3-Year Follow-up of a Randomized Controlled Trial. (2019) (50)
- Alpha2 adrenoceptors in pain modulation: which subtype should be targeted to produce analgesia? (2000) (50)
- Cardiopulmonary and behavioral responses to computer-driven infusion of detomidine in standing horses. (1993) (50)
- Impact on the brain of the inflammatory response to surgery. (2018) (50)
- Alpha-2 adrenergic modulation of sleep: time-of-day-dependent pharmacodynamic profiles of dexmedetomidine and clonidine in the rat. (1995) (50)
- Bone Fracture Exacerbates Murine Ischemic Cerebral Injury (2013) (49)
- Dexmedetomidine Prevents Cognitive Decline by Enhancing Resolution of High Mobility Group Box 1 Protein–induced Inflammation through a Vagomimetic Action in Mice (2017) (49)
- Xenon Pretreatment May Prevent Early Memory Decline after Isoflurane Anesthesia and Surgery in Mice (2011) (48)
- G protein–coupled receptor kinase 2 and group I metabotropic glutamate receptors mediate inflammation‐induced sensitization to excitotoxic neurodegeneration (2013) (46)
- Heat Shock Protein 72 Overexpression Prevents Early Postoperative Memory Decline after Orthopedic Surgery under General Anesthesia in Mice (2011) (45)
- Glucocorticoid inhibition of neuropathic limb edema and cutaneous neurogenic extravasation (2001) (44)
- Brain Stem Opioidergic and GABAergic Neurons Mediate the Antinociceptive Effect of Nitrous Oxide in Fischer Rats (2003) (44)
- Determinants of the Anesthetic Sensitivity of Two-pore Domain Acid-sensitive Potassium Channels (2007) (43)
- Postoperative Impairment of Cognitive Function in Rats (2007) (41)
- Pertussis toxin and 4-aminopyridine differentially affect the hypnotic-anesthetic action of dexmedetomidine and pentobarbital. (1990) (41)
- The glutaminergic, GABAergic, dopaminergic but not cholinergic neurons are susceptible to anaesthesia-induced cell death in the rat developing brain (2011) (41)
- Pertussis toxin-mediated ribosylation of G proteins blocks the hypnotic response to an α 2-agonist in the locus coeruleus of the rat (1992) (41)
- Synergistic interaction between alpha 2-adrenergic agonists and benzodiazepines in rats. (1992) (40)
- Analysis of Anesthetic Action on the Potassium Channels of the Shaker Mutant of Drosophila (1991) (39)
- The hip fracture surgery in elderly patients (HIPELD) study to evaluate xenon anaesthesia for the prevention of postoperative delirium: a multicentre, randomized clinical trial (2018) (39)
- The hip fracture surgery in elderly patients (HIPELD) study to evaluate xenon anaesthesia for the prevention of postoperative delirium: a multicentre, randomized clinical trial (2018) (39)
- Xenon: from stranger to guardian (2005) (38)
- Exercise Prevents Enhanced Postoperative Neuroinflammation and Cognitive Decline and Rectifies the Gut Microbiome in a Rat Model of Metabolic Syndrome (2017) (38)
- Corticotropin-releasing Factor Mediates the Antinociceptive Action of Nitrous Oxide in Rats (2003) (38)
- Independent Preoperative Predictors of Outcomes in Orthopedic and Vascular Surgery: The Influence of Time Interval Between an Acute Coronary Syndrome or Stroke and the Operation (2012) (38)
- The Differential Effects of Nitrous Oxide and Xenon on Extracellular Dopamine Levels in the Rat Nucleus Accumbens: A Microdialysis Study (2006) (37)
- Peripheral orthopaedic surgery down-regulates hippocampal brain-derived neurotrophic factor and impairs remote memory in mouse (2011) (37)
- Fetuses, fentanyl, and the stress response: signals from the beginnings of pain? (2001) (36)
- Combination of Xenon and Isoflurane Produces a Synergistic Protective Effect against Oxygen–Glucose Deprivation Injury in a Neuronal–Glial Co-culture Model (2003) (36)
- Pharmacokinetics of dexmedetomidine combined with therapeutic hypothermia in a piglet asphyxia model (2014) (36)
- Inhaled Xenon Attenuates Myocardial Damage in Comatose Survivors of Out-of-Hospital Cardiac Arrest: The Xe-Hypotheca Trial. (2017) (35)
- Dexmedetomidine Exerts Dose-Dependent Age-Independent Antinociception but Age-Dependent Hypnosis in Fischer Rats (2005) (35)
- Nitrous Oxide Activates GABAergic Neurons in the Spinal Cord in Fischer Rats (2001) (35)
- Strain Differences in the Antinociceptive Effect of Nitrous Oxide on the Tail Flick Test in Rats (2000) (34)
- Role of Pertussis Toxin-sensitive G-Proteins in the Analgesic and Anesthetic Actions of alpha sub 2 -Adrenergic Agonists in the Rat (1995) (34)
- Dexmedetomidine modulates neuroinflammation and improves outcome via alpha2-adrenergic receptor signaling after rat spinal cord injury. (2019) (34)
- Role of Transient Receptor Potential and Acid-sensing Ion Channels in Peripheral Inflammatory Pain (2010) (34)
- Evidence for the Involvement of Spinal Cord &agr;1 Adrenoceptors in Nitrous Oxide–induced Antinociceptive Effects in Fischer Rats (2002) (34)
- Functional effects of activation of alpha-1 adrenoceptors by dexmedetomidine: in vivo and in vitro studies. (1991) (32)
- Isoflurane and an alpha 2-adrenoceptor agonist suppress nociceptive neurotransmission in neonatal rat spinal cord. (1991) (32)
- Verapamil Decreases MAC for Halothane in Dogs (1983) (32)
- Desensitization to the Behavioral Effects of α2-Adrenergic Agonists in Rats (1995) (31)
- Immune cell expression of GABAA receptors and the effects of diazepam on influenza infection (2015) (30)
- Chronic administration of an α 2 adrenergic agonist desensitizes rats to the anesthetic effects of dexmedetomidine (1994) (29)
- Nitrous oxide lacks the antinociceptive effect on the tail flick test in newborn rats. (2000) (29)
- Anesthetic and Hemodynamic Effects of the Alpha2‐adrenergic Agonist, Azepexole, in Isoflurane‐anesthetized Dogs (1988) (29)
- Dexmedetomidine decreases halothane anesthetic requirements in rats. (1989) (28)
- Role of Signal Transduction in Anesthetic Action (1991) (27)
- Pharmacologic characterization of the receptor mediating the hypnotic action of dexmedetomidine. (1989) (27)
- GABAergic Interneurons at Supraspinal and Spinal Levels Differentially Modulate the Antinociceptive Effect of Nitrous Oxide in Fischer Rats (2002) (27)
- The Feasibility and Utility of Continuous Sleep Monitoring in Critically Ill Patients Using a Portable Electroencephalography Monitor (2016) (27)
- Alpha-2 adrenergic agonists (1997) (27)
- Halothane concentration does not alter the threshold for epinephrine-induced arrhythmias in dogs. (1984) (26)
- Dexmedetomidine Exerts an Anti-inflammatory Effect via α2 Adrenoceptors to Prevent Lipopolysaccharide-induced Cognitive Decline in Mice (2020) (26)
- Expansion of Gas Bubbles by Nitrous Oxide and Xenon (2006) (25)
- Nitrous oxide exerts age-dependent antinociceptive effects in Fischer rats (2002) (25)
- Action of the stereoisomers of medetomidine, in halothane-anesthetized dogs. (1989) (25)
- The α2-adrenoceptor agonist dexmedetomidine increases the apparent potency of the volatile anesthetic isoflurane in rats in vivo and in hippocampal slice in vitro (1991) (25)
- Sympatholytic and Minimum Anesthetic Concentration-sparing Responses are Preserved in Rats Rendered Tolerant to the Hypnotic and Analgesic Action of Dexmedetomidine, a Selective alpha sub 2 -adrenergic Agonist (1996) (25)
- Xenon induces transcription of ADNP in neonatal rat brain (2008) (25)
- Prolonged Hyporesponsiveness of Vascular Smooth Muscle Contraction after Halothane Anesthesia in Rabbits (1985) (24)
- Dexmedetomidine for sedation and perioperative management of critically ill patients (2006) (24)
- Hypnotic and analgesic effects of the alpha 2-adrenergic agonist dexmedetomidine in morphine-tolerant rats. (1996) (24)
- Opioidergic and adrenergic modulation of formalin-evoked spinal c-fos mRNA expression and nocifensive behavior in the rat. (1999) (24)
- Past, present, and future of nitrous oxide (2018) (24)
- A comparison of etomidate and thiopental anesthesia for cardioversion. (1991) (23)
- Clinical interactions with alpha-2-adrenergic agonists in anesthetic practice. (1992) (23)
- The Role of Microglia in Perioperative Neuroinflammation and Neurocognitive Disorders (2021) (23)
- Fragmented Sleep Enhances Postoperative Neuroinflammation but Not Cognitive Dysfunction (2017) (23)
- Endoglin Deficiency Impairs Stroke Recovery (2014) (23)
- Rested and refreshed after anesthesia? Overlapping neurobiologic mechanisms of sleep and anesthesia. (2004) (23)
- Xenon Exerts Age-independent Antinociception in Fischer Rats (2004) (23)
- Isoflurane exerts antinociceptive and hypnotic properties at all ages in Fischer rats. (2005) (23)
- Preclinical neuroprotective actions of xenon and possible implications for human therapeutics: a narrative review (2016) (22)
- Epinephrine infusion induces hyporesponsiveness of vascular smooth muscle. (1985) (22)
- Alpha1-adrenergic Blockade Raises Epinephrine—Arrhythmia Threshold in Halothane‐anesthetized Dogs in a Dose‐dependent Fashion (1985) (22)
- Halothane hepatotoxicity in Fischer 344 rats pretreated with isoniazid. (1987) (22)
- The Antinociceptive Effect of Transcranial Electrostimulation with Combined Direct and Alternating Current in Freely Moving Rats (2004) (21)
- A Multicenter Study of the Epidemiology of Hepatitis B in Anesthesia Residents (1985) (21)
- Neuroinflammation and postoperative cognitive dysfunction: can anaesthesia be therapeutic? (2010) (20)
- Neuroprotective Properties of Xenon (2019) (20)
- L-phenylisopropyladenosine (L-PIA) diminishes halothane anesthetic requirements and decreases noradrenergic neurotransmission in rats. (1988) (19)
- Comparison of sedation with dexmedetomidine versus lorazepam in septic ICU patients (2008) (19)
- Colchicine treatment of the sciatic nerve reduces neurogenic extravasation, but does not affect nociceptive thresholds or collateral sprouting in neuropathic or normal rats (1998) (19)
- Dexmedetomidine does not attenuate increases in excitatory amino acids after transient global ischemia in the rabbit. (1994) (19)
- Neuroinflammation is a putative target for the prevention and treatment of perioperative neurocognitive disorders. (2019) (19)
- The Hip Fracture Surgery in Elderly Patients (HIPELD) study: protocol for a randomized, multicenter controlled trial evaluating the effect of xenon on postoperative delirium in older patients undergoing hip fracture surgery (2012) (19)
- Dexmedetomidine for prevention of postoperative delirium in older adults undergoing oesophagectomy with total intravenous anaesthesia (2020) (19)
- Nifedipine, an L-type calcium channel blocker, restores the hypnotic response in rats made tolerant to the alpha-2 adrenergic agonist dexmedetomidine. (1997) (19)
- Central alpha 1-adrenoceptor stimulation functionally antagonizes the hypnotic response to dexmedetomidine, an alpha 2-adrenoceptor agonist. (1991) (19)
- Activation of alpha-1 adrenergic receptors modulates the control of left/right sidedness in rat embryos. (1992) (18)
- Editorial I Can we characterize the central nervous system actions of α2‐adrenergic agonists? (2001) (18)
- Halothane‐Epinephrine Arrhythmias and Adrenergic Responsiveness after Chronic Imipramine Administration in Dogs (1984) (18)
- A clinically relevant model of perinatal global ischemic brain damage in rats (2011) (18)
- Role of Imidazoline‐preferring Receptors in the Genesis of Epinephrine‐induced Arrhythmias in Halothane‐anesthetized Dogs (1993) (18)
- Modulating role of dopamine on anesthetic requirements (1990) (17)
- Xenon Up-regulates Several Genes That are not Up-regulated by Nitrous Oxide (2008) (17)
- Anesthetic pharmacology : physiologic principles and clinical practice : a companion to Miller's Anesthesia (2004) (17)
- Chronic desipramine treatment desensitizes the rat to anesthetic and antinociceptive effects of the alpha2-adrenergic agonist dexmedetomidine. (1998) (17)
- Mechanism of halothane-induced inhibition of isoproterenol-stimulated lipolysis in isolated rat adipocytes. (1988) (17)
- A Multicenter Study of the Prevalence of Hepatitis B Viral Serologic Markers in Anesthesia Personnel (1984) (16)
- Modulating role of dopamine on anesthetic requirements. (1988) (16)
- Noradrenergic trespass in anesthetic and sedative states. (2012) (16)
- Sleep and Anesthesia - Common mechanisms of action. (2013) (16)
- Can we characterize the central nervous system actions of alpha2-adrenergic agonists? (2001) (16)
- Alpha 2-adrenoceptors inhibit a nociceptive response in neonatal rat spinal cord. (1991) (16)
- Role of serotonergic neurotransmission in the hypnotic response to dexmedetomidine, an alpha 2-adrenoceptor agonist. (1996) (16)
- Role of the sympathetic nervous system in the maintenance of hypertension in rats harboring pheochromocytoma. (1987) (16)
- Alpha-2 agonists: can they modify the outcomes in the Postanesthesia Care Unit? (2005) (16)
- Blocking Kv1.3 potassium channels psrevents postoperative neuroinflammation and cognitive decline without impairing wound healing in mice. (2020) (15)
- Attenuation of central α2 adrenergic action in diabetic rats (1991) (14)
- Argon neuroprotection (2010) (14)
- Dexmedetomidine synergism with midazolam in the elevated plus-maze test in rats (2005) (14)
- Exaggerated Acute Lung Injury and Impaired Antibacterial Defenses During Staphylococcus aureus Infection in Rats with the Metabolic Syndrome (2015) (14)
- G-protein-coupled receptors. (2008) (14)
- Clinical implications of membrane receptor function in anesthesia. (1981) (13)
- Substitution of a mutant alpha 2 a-adrenergic receptor via " hit and run " gene targeting reveals Maze (1997) (13)
- Pulmonary and systemic hemodynamic effects of central venous and left atrial sympathomimetic drug administration in the dog. (1987) (13)
- Taking the lead in research into postoperative cognitive dysfunction. (2008) (13)
- In vivo mutation of the alpha 2A-adrenergic receptor by homologous recombination reveals the role of this receptor subtype in multiple physiological processes. (1998) (13)
- Halothane Concentration Does Not Alter the Threshold for Epinephrine‐induced Arrhythmias in Dogs (1985) (13)
- Protecting the Brain With Xenon Anesthesia for Neurosurgical Procedures (2018) (12)
- Desensitization to the Behavioral Effects of alpha sub 2 -Adrenergic Agonists in Rats (1995) (12)
- Neuroprotection by the α2-Adrenoreceptor Agonist Dexmedetomidine in a Focal Model of Cerebral Ischemia (1993) (12)
- Are cholinergic pathways involved in the anesthetic response to α2 agonists (1998) (12)
- Sedation & immunomodulation. (2009) (12)
- α2-Adrenoceptor Agonists and Anesthesia (1994) (12)
- Effects of Volatile Anesthetics or Fentanyl on Hepatic Function in Cirrhotic Rats (1985) (11)
- Xenon and the inflammatory response to cardiopulmonary bypass in the rat. (2005) (11)
- Alpha-2B adrenoceptor activation inhibits a nociceptive response in the spinal cord of the neonatal rat (1990) (11)
- Relation between acute and long-term cognitive decline after surgery: Influence of metabolic syndrome (2015) (11)
- Nitrous oxide discretely up-regulates nNOS and p53 in neonatal rat brain. (2010) (11)
- Role of signal transduction in anesthetic action. Alpha 2 adrenergic agonists. (1991) (11)
- Mechanism for desensitization of beta-adrenergic receptor-stimulated lipolysis in adipocytes from rats harboring pheochromocytoma. (1988) (10)
- $aL‐Adrenergic Responsiveness Correlates with Epinephrine Dose for Arrhythmias during Halothane Anesthesia in Dogs (1984) (10)
- Halothane Anesthetic Requirements Are Not Affected by Aminophylline Treatment in Rats and Dogs (1986) (10)
- Comprar Anesthetic Pharmacology. Basic Principles And Clinical Practice | Alex S. Evers | 9780521896665 | Cambridge University Press (2011) (9)
- Capsaicin sensitive afferents mediate the development of heat hyperalgesia and hindpaw edema after sciatic section in rats (2002) (9)
- Special issue on postoperative cognitive dysfunction: selected reports from the journal-sponsored symposium. (2007) (9)
- Transmembrane signalling and the holy grail of anesthesia. (1990) (9)
- Dexmedetomidine and opioid interactions: defining the role of dexmedetomidine for intensive care unit sedation. (2004) (9)
- From Bench to Bedside and Back Again: A Personal Journey with Dexmedetomidine. (2016) (9)
- The Role of the Craniospinal Nerves in Mediating the Antinociceptive Effect of Transcranial Electrostimulation in the Rat (2006) (9)
- A1167 VENTILATORY EFFECTS OF DEXMEDETOMIDINE IN HUMANS (1990) (8)
- Developmental Variation in Nitrous Oxide–induced c-Fos Expression in Fischer Rat Spinal Cord (2002) (8)
- CHARACTERIZATION OF THE ALPHA2 ADRENOCEPTOR-EFFECTOR MECHANISM FOR THE HYPNOTIC ACTION OF MPV-1440 IN RATS (1988) (8)
- Postcountershock Myocardial Damage after Pretreatment with Adrenergic and Calcium Channel Antagonists in Halothane‐anesthetized Dogs (1985) (8)
- alpha 2-Adrenergic agonist receptors, sites, and mechanisms of action (1992) (8)
- Expecting the unexpected. (2008) (8)
- Adrenergic and cholinergic compounds. (2007) (8)
- Pharmacology of nitrous oxide (2001) (7)
- Unraveling the interactions between postoperative infection, surgery, and inflammation in post-operative cognitive dysfunction: BAPCPC1–4 (2010) (7)
- Aminophylline shortens thiopental sleep-time and enhances noradrenergic neurotransmission in rats (1986) (7)
- Implementation of a radioreceptor assay for dexmedetomidine. (1993) (7)
- Initiating Mechanisms of Surgery-induced Memory Decline: The Role of HMGB1. (2016) (7)
- Functional molecular biology of the TRPV1 ion channel (2008) (7)
- Sedative but Not Analgesic &agr;2 Agonist Tolerance Is Blocked by NMDA Receptor and Nitric Oxide Synthase Inhibitors (2001) (7)
- The individual, the system, and medical error (2003) (7)
- IS DEXMEDETOMIDINEʼS ANESTHETIC ACTION DEPENDENT ON ISORECEPTOR SELECTIVITY (1989) (7)
- Hypnotic and Analgesic Effects of the alpha2-Adrenergic Agonist Dexmedetomidine in Morphine-Tolerant Rats (1996) (7)
- Perioperative use of alpha-2 adrenergic agonists (1996) (6)
- Xenon Does Not Cause Apoptotic Neurodegeneration In The Neonatal Rat, And Protects Against Isoflurane-Induced Apoptosis (2004) (6)
- Anesthesia and ion channel function in the autonomic nervous system. (1989) (6)
- High-Mobility Group Box-1 and Its Potential Role in Perioperative Neurocognitive Disorders (2021) (6)
- Reprogramming of the infant brain by surgery with general anesthesia. (2012) (6)
- MYOCARDIAL BETA-ADRENOCEPTOR DENSITY IS DECREASED BY HALOTHANE IN DOGS AS ASSESSED BY POSITRON EMISSION TOMOGRAPHY (1987) (6)
- Chronic Treatment With Dexmedetomidine Desensitizes α2-Adrenergic Signal Transduction (1997) (6)
- A411 SEDATIVE AND HEMODYNAMIC EFFECTS OF DEXMEDETOMIDINE IN HUMANS (1990) (6)
- Design of Clinical Trials Evaluating Sedation in Critically Ill Adults Undergoing Mechanical Ventilation: Recommendations From Sedation Consortium on Endpoints and Procedures for Treatment, Education, and Research (SCEPTER) Recommendation III (2021) (6)
- Will Xenon Be a Valuable Addition in Perioperative and Critical Care Settings? (2016) (5)
- Theseus, the Labyrinth, and the Minotaur of anaesthetic-induced developmental neurotoxicity. (2017) (5)
- Preoperative sedentary behavior is neither a risk factor for perioperative neurocognitive disorders nor associated with an increase in peripheral inflammation, a prospective observational cohort study (2020) (5)
- Controversial issues in adult and paediatric ambulatory anaesthesia: is there a role for alpha-2 agonists in conscious sedation in adults and paediatric ambulatory surgical practice? (2000) (5)
- Interleukin-6 trans-signalling in hippocampal CA1 neurones mediates perioperative neurocognitive disorders in mice. (2022) (5)
- Are cholinergic pathways involved in the anesthetic response to alpha2 agonists. (1998) (5)
- Simulation in anaesthesia (2000) (5)
- Beta-receptor blockade following the use of eye drops. (1980) (5)
- Alpha-2 adrenergic agonists in anesthesiology (1996) (4)
- Chapter 12 Clinical Uses of α2 Agonists (1992) (4)
- Restoring Order to Postoperative Neurocognitive Disorders. (2018) (4)
- Does correcting the numbers improve long-term outcome? (2009) (4)
- COMPARISON OF CARDIOPULMONARY RESPONSES TO DETOMIDINE ADMINISTERED AS AN INTRAVENOUS STEADY-STATE INFUSION VS INTRAVENOUS BOLUS IN STANDING HORSES (1991) (4)
- Epinephrine Arrhythmogenicity Is Enhanced by Acute, but Not Chronic, Aminophylline Administration during Halothane Anesthesia in Dogs (1986) (4)
- Evidence for the Involvement of Spinal Cord (2002) (4)
- Correction: Activation of α-7 Nicotinic Acetylcholine Receptor Reduces Ischemic Stroke Injury through Reduction of Pro-Inflammatory Macrophages and Oxidative Stress (2016) (4)
- Methods for Defining the Neuroprotective Properties of Xenon. (2018) (4)
- The Pharmacokinetics of IV Dexmedetomidine in Adults (1991) (3)
- Dissociation of Hypnotic-Anesthetic Actions of α2 Agonists From Cyclic AMP in the Rat (1997) (3)
- Effect of Intraoperative Dexmedetomidine on Recovery of Gastrointestinal Function After Abdominal Surgery in Older Adults (2021) (3)
- Attenuation of central alpha 2 adrenergic action in diabetic rats. (1991) (3)
- N‐(Imidazolidin‐2‐ylidene)‐1‐arylmethanamine Oxides: Synthesis, Structure and Pharmacological Evaluation (2012) (3)
- SYNERGISTIC INTERACTION BETWEEN α2ADRENERGIC AGONISTS & BENZODIAZEPINES IN RATS (1991) (3)
- Xenon Preconditions Against Hypoxic-Ischemic Induced Brain Damage in the Neonatal Rat (2004) (3)
- Abstracts presented at the 8th International Symposium on Memory and Awareness in Anesthesia (MAA8) Milwaukee, WI, USA, June 2–5, 2011 (2012) (3)
- THE ROLE OF PERTUSSIS TOXIN-SENSITIVE G PROTEINS IN THE ANESTHETIC ACTION OF HALOTHANE IN RATS (1988) (3)
- Feasibility and Safety of Delivering Xenon to Patients Undergoing Coronary Artery Bypass Graft Surgery While on Cardiopulmonary Bypass (2006) (3)
- Dexmedetomidine: A Viewpoint by Professor Mervyn Maze (2000) (3)
- Age-Related Perioperative Neurocognitive Disorders: Experimental Models and Druggable Targets. (2022) (3)
- HALOTHANE DECREASES ARRHYTHMOGENIC THRESHOLD FOR EPINEPHRINE THROUGH α AND β ADRENOCEPTOR MECHANISMS (1982) (3)
- HIGH TIME RESOLUTION CATECHOLAMINE SAMPLING DURING CARDIOPULMONARY BYPASS (1985) (3)
- DECREASED POTASSIUM CHANNEL CONDUCTANCE, ENCODED BY THE SHAKER LOCUS IN DROSOPHILA, INCREASES VOLATILE ANESTHETIC REQUIREMENTS (1989) (3)
- Mechanism of Antiarrhythmic Effect of Dexmedetomidine on Epinephrine-induced Arrhythmias (1991) (2)
- AMINDPHYI1INE DOES NOT INHIBIT ERDNQ-DOCNSTRICnON DURING HAI0THANE ANESTHESIA (1986) (2)
- N‐(Imidazolidin‐2‐ylidene)‐1‐arylmethanamine Oxides: Synthesis, Structure and Pharmacological Evaluation. (2012) (2)
- ADRENERGIC HYPORESPONSIVENESS OF VASCULAR CONTRACTILITY FOLLOWING EPINEPHRINE INFUSION (1985) (2)
- PERTURBATION OF ION CONDUCTANCE IN THE LOCUS COERULEUS ALTERS THE HYPNOTIC RESPONSE TO DEXMEDETOMIDINE IN RATS (1992) (2)
- Halothane Anesthesia Does Not Exacerbate Hepatic Dysfunction in Cirrhotic Rats (1985) (2)
- Simulator Teaching for Operating Department Practitioners. (2006) (2)
- Chronic treatment with dexmedetomidine desensitizes alpha 2-adrenergic signal transduction. (1997) (2)
- Current Research in Anesthesia and Trends in Clinical Applications (1997) (2)
- Effects Of A Sedative/analgesic α2, Adrenergic Agonist, Dexmedetomidine, On The Spinal Cord Of Newborn Rats (1989) (2)
- Clinical Uses of &agr;2-Adrenergic Agonists (2000) (2)
- Lactate Clearance in the Acutely Traumatized Patient (2012) (2)
- PULMONARY AND SYSTEMIC HEMODYNAMIC EFFECTS OF VENOUS AND LEFT ATRIAL VASOPRESSOR INFUSIONS IN THE DOG (1985) (2)
- "A Time of Opportunity": Patient Safety and the Perioperative Surgical Home. (2016) (2)
- Antiarrhythmic effect of verapamil may be independent of calcium channel blockade. (1985) (1)
- AMINOPHYLLINE DOES NOT ALTER THE MAC FOR HALOTHANE IN RATS AND DOGS (1985) (1)
- Drugs for reversal of neuromuscular blockade (2011) (1)
- "Exciting" aspects of opiate receptor signal transduction. (1997) (1)
- Sleep, Memory, and Consciousness (2010) (1)
- BRAIN B-AMYLOID IN COGNITIVELY NORMAL SUBJECTS IS A PREDICTOR OF EARLY POSTOPERATIVE COGNITIVE DYSFUNCTION (2014) (1)
- Mechanisms and Consequences of Anesthetic‐Induced Neuroapoptosis in the Developing Brain (2012) (1)
- Combination of Xenon and Hypothermia Against Apoptotic and Necrotic Neuronal Death Induced by Hypoxia-Ischemia in Neonatal Rats (2004) (1)
- Room D, 10/17/2000 9: 00 AM - 11: 00 AM (PS) Nitrous Oxide Induced Met-enkephalin Release Provokes Dopamine Release in Rat Adrenal Medulla Cultured In Vitro A-758 (2000) (1)
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- Longitudinal Profiling of Plasma Cytokines and Its Association With Postoperative Delirium in Elderly Patients Undergoing Major Lower Limb Surgery: A Prospective Observational Study (2022) (1)
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- Neuroprotection by nitrous oxide and xenon and its relation to minimum alveolar concentration. Authors' reply (2004) (1)
- Dissociation of hypnotic-anesthetic actions of alpha 2 agonists from cyclic AMP in the rat. (1997) (1)
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- EFFECT OF CLONIDINE ON VENTILATION, AND VENTILATORY DEPRESSION PRODUCED BY ALFENTANIL IN VOLUNTEERS (1991) (1)
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- HALOTHANE HAC IS STEREOSPECIFICALLY REDUCED BY MEDETOMIDINE, AN ALPHA2 AGONIST (1988) (1)
- AMINOPHYLLINE SHORTENS BARBITURATE SLEEP TIME IN RATS (1985) (1)
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- Comorbidities and Postoperative Neurocognitive Disorder (2019) (1)
- Relevance to Clinical Anesthesia of Anesthetic‐Induced Neurotoxicity in Developing Animals (2012) (1)
- Xenon Exhibits Antinociceptive Effect on the Formalin Test in Newborn Fischer Rats: [2002][A-1291] (2002) (1)
- Contribution of intraoperative electroencephalogram suppression to frailty-associated postoperative delirium: mediation analysis of a prospective surgical cohort. (2022) (1)
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- SURGERY AND ANESTHESIA LEAD TO COGNITIVE DECLINE AT 1-YEAR AFTER SURGERY IN COGNITIVELY NORMAL SUBJECTS WITH BRAIN B-AMYLOID (2014) (0)
- Room D, 10/17/2000 2: 00 PM - 4: 00 PM (PS) Nitrous Oxide-Induced Antinociception and Noradrenergic Activation Are Not Mediated by Enkephalinergic Mechanism in Mice A-797 (2000) (0)
- Neuroprotective Properties of Xenon (2019) (0)
- Hsp72 Overexpression Prevents Early Postoperative Memory Decline after Orthopedic Surgery Under General Anesthesia in Mice (2011) (0)
- Involvement of KCa3.1 channel activity in immediate perioperative cognitive and neuroinflammatory outcomes (2023) (0)
- Combined Neuroprotection by Xenon and Dexmedetomidine in vitro (2004) (0)
- NMDA RECEPTOR AND NITRIC OXIDE SYNTHASE ARE NECESSARY FOR THE INDUCTION, BUT NOT EXPRESSION, OF TOLERANCE TO [Greek small letter alpha]2 AGONISTS IN RATS (1998) (0)
- Room H, 10/16/2000 2: 00 PM - 4: 00 PM (PS) Functional Evidence for the Lack of Antinociceptive Effect of Nitrous Oxide in Newborn Rats A-1256 (2000) (0)
- MOLECULAR MECHANISM FOR HALOTHANE-INDUCED ß-ADRENERGIC HYPORESPONSIVENESS IN VITRO (1988) (0)
- Paradoxical increases in anterior cingulate cortex activity during nitrous oxide-induced analgesia reveal a signature of pain affect (2023) (0)
- ADENOSINE AGCNIST DECREASES HALOTHANE MAC AND NORADRENERGIC NEUROTRANSMISSION IN RATS (1988) (0)
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