Michael C. Phillips
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Computer Science
Michael C. Phillips's Degrees
- PhD Computer Science Stanford University
- Masters Computer Science University of California, Berkeley
- Bachelors Computer Science University of California, Berkeley
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(Suggest an Edit or Addition)Michael C. Phillips's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus (2010) (1048)
- Cholesterol efflux and atheroprotection: advancing the concept of reverse cholesterol transport. (2012) (779)
- Use of cyclodextrins for manipulating cellular cholesterol content. (1997) (745)
- Scavenger Receptor BI Promotes High Density Lipoprotein-mediated Cellular Cholesterol Efflux* (1997) (735)
- Cellular Cholesterol Efflux Mediated by Cyclodextrins (*) (1995) (726)
- Proteins at liquid interfaces: I. Kinetics of adsorption and surface denaturation (1979) (655)
- Cellular Cholesterol Efflux Mediated by Cyclodextrins (1996) (585)
- Importance of different pathways of cellular cholesterol efflux. (2003) (531)
- Proteins at liquid interfaces (1979) (527)
- Cell cholesterol efflux: integration of old and new observations provides new insights. (1999) (518)
- Mechanisms and consequences of cellular cholesterol exchange and transfer. (1987) (511)
- Monolayer characteristics of saturated 1,2,-diacyl phosphatidylcholines (lecithins) and phosphatidylethanolamines at the air-water interface. (1968) (484)
- Cholesterol transport between cells and high-density lipoproteins. (1991) (446)
- Molecular Mechanisms of Cellular Cholesterol Efflux* (2014) (432)
- Proteins at liquid interfaces: II. Adsorption isotherms (1979) (396)
- High-density lipoprotein heterogeneity and function in reverse cholesterol transport (2010) (329)
- Mechanism of ATP-binding Cassette Transporter A1-mediated Cellular Lipid Efflux to Apolipoprotein A-I and Formation of High Density Lipoprotein Particles* (2007) (324)
- Mechanism of cholesterol and phosphatidylcholine exchange or transfer between unilamellar vesicles. (1981) (324)
- Scavenger Receptor Class B Type I as a Mediator of Cellular Cholesterol Efflux to Lipoproteins and Phospholipid Acceptors* (1998) (304)
- The roles of different pathways in the release of cholesterol from macrophages Published, JLR Papers in Press, August 29, 2007. (2007) (299)
- Differences in stability among the human apolipoprotein E isoforms determined by the amino-terminal domain. (2000) (282)
- Class B scavenger receptor-mediated intestinal absorption of dietary beta-carotene and cholesterol. (2005) (272)
- Molecular interactions in mixed lecithin systems. (1970) (271)
- Identification of a receptor mediating absorption of dietary cholesterol in the intestine. (1998) (248)
- The Physical State of Phospholipids and Cholesterol in Monolayers, Bilayers, and Membranes (1972) (246)
- Apolipoproteins, membrane cholesterol domains, and the regulation of cholesterol efflux. (1992) (246)
- On the nature of hydrocarbon chain motions in lipid liquid crystals (1969) (233)
- Scavenger receptor BI (SR-BI) mediates free cholesterol flux independently of HDL tethering to the cell surface. (1999) (231)
- High density lipoprotein structure-function and role in reverse cholesterol transport. (2010) (228)
- Influence of molecular packing and phospholipid type on rates of cholesterol exchange. (1986) (222)
- Effects of increasing hydrophobicity on the physical-chemical and biological properties of a class A amphipathic helical peptide. (2001) (214)
- Nuclear magnetic resonance study of lecithin-cholesterol interactions. (1972) (213)
- Hepatic sortilin regulates both apolipoprotein B secretion and LDL catabolism. (2012) (209)
- Contributions of domain structure and lipid interaction to the functionality of exchangeable human apolipoproteins. (2004) (206)
- Apolipoprotein E isoforms and lipoprotein metabolism (2014) (206)
- Efflux of cellular cholesterol and phospholipid to lipid-free apolipoproteins and class A amphipathic peptides. (1995) (197)
- Scavenger receptor BI and cholesterol trafficking. (1999) (191)
- Only the two end helixes of eight tandem amphipathic helical domains of human apo A-I have significant lipid affinity. Implications for HDL assembly. (1996) (183)
- Increased Low-Density Lipoprotein Oxidation and Impaired High-Density Lipoprotein Antioxidant Defense Are Associated With Increased Macrophage Homing and Atherosclerosis in Dyslipidemic Obese Mice: LCAT Gene Transfer Decreases Atherosclerosis (2003) (179)
- Domain Structure and Lipid Interaction in Human Apolipoproteins A-I and E, a General Model* (2003) (175)
- Characterization of nascent HDL particles and microparticles formed by ABCA1-mediated efflux of cellular lipids to apoA-I Published, JLR Papers in Press, January 17, 2006. (2006) (172)
- A sensitive assay for ABCA1-mediated cholesterol efflux using BODIPY-cholesterol (2011) (171)
- Cyclodextrins as catalysts for the removal of cholesterol from macrophage foam cells. (1997) (166)
- Cardiovascular protection by ApoE and ApoE-HDL linked to suppression of ECM gene expression and arterial stiffening. (2012) (162)
- The bidirectional flux of cholesterol between cells and lipoproteins. Effects of phospholipid depletion of high density lipoprotein. (1986) (162)
- Effects of acceptor composition and mechanism of ABCG1-mediated cellular free cholesterol efflux* (2009) (161)
- Effects of intracellular free cholesterol accumulation on macrophage viability: a model for foam cell death. (1998) (161)
- Differences between conformations of lecithin and phosphatidylethanolamine polar groups and their effects on interactions of phospholipid bilayer membranes. (1972) (157)
- Crystallization of free cholesterol in model macrophage foam cells. (1999) (153)
- Helical structure and stability in human apolipoprotein A-I by hydrogen exchange and mass spectrometry (2009) (148)
- The influence of the triglyceride content of low density lipoprotein on the interaction of apolipoprotein B-100 with cells. (1988) (146)
- Mechanism of cholesterol efflux from cells. Effects of acceptor structure and concentration. (1982) (146)
- Thermodynamic and molecular basis for dissimilar cholesterol-solubilizing capacities by micellar solutions of bile salts: cases of sodium chenodeoxycholate and sodium ursodeoxycholate and their glycine and taurine conjugates. (1981) (145)
- Ion-binding to phospholipids. Interaction of calcium and lanthanide ions with phosphatidylcholine (lecithin). (1975) (144)
- CD36 Mediates Both Cellular Uptake of Very Long Chain Fatty Acids and Their Intestinal Absorption in Mice* (2008) (143)
- The charge and structural stability of apolipoprotein A-I in discoidal and spherical recombinant high density lipoprotein particles. (1992) (140)
- Proteins at liquid interfaces. V. Shear properties (1980) (139)
- The Effect of High Density Lipoprotein Phospholipid Acyl Chain Composition on the Efflux of Cellular Free Cholesterol (*) (1995) (139)
- Quantitative measurement of lipoprotein surface charge by agarose gel electrophoresis. (1992) (138)
- Mixed monolayers of phospholipids and cholesterol. (1969) (138)
- Mechanism of ion escape from phosphatidylcholine and phosphatidylserine single bilayer vesicles. (1973) (138)
- Monolayer characteristics of some 1,2-diacyl, I-alkyl-2-acyl and 1,2-dialkyl phospholipids at the air-water interface. (1971) (136)
- Kinetics of phosphatidylcholine and lysophosphatidylcholine exchange between unilamellar vesicles. (1984) (136)
- Ion‐Binding to Phospholipids (1976) (135)
- Mechanisms of cholesterol-lowering effects of dietary insoluble fibres: relationships with intestinal and hepatic cholesterol parameters (2005) (133)
- Conformation of the lecithin polar group in charged vesicles (1976) (125)
- Effects of Acceptor Particle Size on the Efflux of Cellular Free Cholesterol (*) (1995) (125)
- The conformation of apolipoprotein A-I in discoidal and spherical recombinant high density lipoprotein particles. 13C NMR studies of lysine ionization behavior. (1992) (125)
- Proteins at liquid interfaces. IV. Dilatational properties (1980) (124)
- Effects of Apolipoprotein A-I on ATP-binding Cassette Transporter A1-mediated Efflux of Macrophage Phospholipid and Cholesterol (2003) (123)
- The effects of temperature on the composition and physical properties of the lipids of Pseudomonas fluorescens. (1971) (122)
- Efflux of cholesterol from different cellular pools. (2000) (122)
- Apolipoprotein B-100 conformation and particle surface charge in human LDL subspecies: implication for LDL receptor interaction. (1998) (121)
- Mechanism of the hepatic lipase induced accumulation of high-density lipoprotein cholesterol by cells in culture. (1985) (120)
- ABCA1-Induced Cell Surface Binding Sites for ApoA-I (2007) (120)
- Mechanism of cholesterol efflux from cells (1980) (120)
- α-Helix Formation Is Required for High Affinity Binding of Human Apolipoprotein A-I to Lipids* (2004) (119)
- Binding and Cross-linking Studies Show That Scavenger Receptor BI Interacts with Multiple Sites in Apolipoprotein A-I and Identify the Class A Amphipathic α-Helix as a Recognition Motif* (2000) (117)
- Packing of cholesterol molecules in human low-density lipoprotein. (1984) (116)
- The inter- and intra-molecular mixing of hydrocarbon chains in lecithin-water systems. (1972) (115)
- The interaction of ions with phosphatidylcholine bilayers (1977) (114)
- High density lipoprotein structure. (2003) (109)
- Effect of end group blockage on the properties of a class A amphipathic helical peptide (1993) (108)
- Interactions of the Polar Groups of Phospholipid Bilayer Membranes (1979) (108)
- Scavenger Receptor Class B, Type I-mediated Uptake of Various Lipids into Cells (2001) (107)
- New insights into the determination of HDL structure by apolipoproteins: Thematic review series: high density lipoprotein structure, function, and metabolism. (2012) (107)
- The stoichiometry and dynamics of lecithin-cholesterol clusters in bilayer membranes. (1974) (105)
- Truncation of the amino terminus of human apolipoprotein A-I substantially alters only the lipid-free conformation. (1997) (105)
- The molecular basis for the difference in charge between pre-beta- and alpha-migrating high density lipoproteins. (1994) (103)
- Lipid Binding-induced Conformational Change in Human Apolipoprotein E (2001) (102)
- Mechanisms of high density lipoprotein-mediated efflux of cholesterol from cell plasma membranes. (1998) (101)
- Induction of cellular cholesterol efflux to lipid-free apolipoprotein A-I by cAMP. (1999) (100)
- The conformation and aggregation of bovine β‐casein A. I. Molecular aspects of thermal aggregation (1979) (99)
- Effect of dietary supplementation with n-3 polyunsaturated fatty acids on physical properties and metabolism of low density lipoprotein in humans. (1992) (98)
- Cholesterol flux between cells and high density lipoprotein. Lack of relationship to specific binding of the lipoprotein to the cell surface. (1987) (97)
- The stability and structure of cholesterol-rich codispersions of cholesterol and phosphatidylcholine. (1982) (96)
- Differences in the interaction of inorganic and organic (hydrophobic) cations with phosphatidylserine membranes. (1975) (94)
- Reverse cholesterol transport. (1986) (94)
- Removal of cellular cholesterol by pre-beta-HDL involves plasma membrane microsolubilization. (1997) (92)
- Scavenger receptor BI (SR-BI) clustered on microvillar extensions suggests that this plasma membrane domain is a way station for cholesterol trafficking between cells and high-density lipoprotein. (2003) (91)
- Is ABCA1 a lipid transfer protein? (2018) (90)
- Cholesterol efflux from cells to immunopurified subfractions of human high density lipoprotein: LP-AI and LP-AI/AII. (1991) (89)
- Serum albumin acts as a shuttle to enhance cholesterol efflux from cells[S] (2013) (89)
- New Insights into the Heparan Sulfate Proteoglycan-binding Activity of Apolipoprotein E* (2001) (87)
- A human APOC3 missense variant and monoclonal antibody accelerate apoC-III clearance and lower triglyceride-rich lipoprotein levels (2017) (86)
- Arg123-Tyr166 Domain of Human ApoA-I Is Critical for HDL-Mediated Inhibition of Macrophage Homing and Early Atherosclerosis in Mice (2001) (85)
- The C-terminal lipid-binding domain of apolipoprotein E is a highly efficient mediator of ABCA1-dependent cholesterol efflux that promotes the assembly of high-density lipoproteins. (2007) (85)
- Spreading of solid glycerides and phospholipids at the air—water interface (1974) (85)
- Molecular packing of high-density and low-density lipoprotein surface lipids and apolipoprotein A-I binding. (1989) (84)
- Influence of apoE domain structure and polymorphism on the kinetics of phospholipid vesicle solubilization DOI 10.1194/jlr.M200157-JLR200 (2002) (83)
- Characterization and properties of pre beta-HDL particles formed by ABCA1-mediated cellular lipid efflux to apoA-I. (2008) (83)
- Kinetics and mechanism of free cholesterol exchange between human serum high- and low-density lipoproteins. (1982) (81)
- Effects of Polymorphism on the Lipid Interaction of Human Apolipoprotein E* (2003) (81)
- The influence of cellular and lipoprotein cholesterol contents on the flux of cholesterol between fibroblasts and high density lipoprotein. (1988) (80)
- The efflux of lysosomal cholesterol from cells. (1990) (79)
- Scavenger Receptor Class B Type I-mediated Cholesteryl Ester-selective Uptake and Efflux of Unesterified Cholesterol (2004) (78)
- Comparison of the stabilities and unfolding pathways of human apolipoprotein E isoforms by differential scanning calorimetry and circular dichroism. (2002) (77)
- Characterization of the Heparin Binding Sites in Human Apolipoprotein E* (2003) (76)
- Aromatic Residue Position on the Nonpolar Face of Class A Amphipathic Helical Peptides Determines Biological Activity* (2004) (75)
- Apolipoprotein A-I helical structure and stability in discoidal high-density lipoprotein (HDL) particles by hydrogen exchange and mass spectrometry (2012) (75)
- Ion Permeability of Phospholipid Bilayers (1972) (74)
- Influence of ApoA-I Structure on the ABCA1-mediated Efflux of Cellular Lipids* (2004) (74)
- Helix Orientation of the Functional Domains in Apolipoprotein E in Discoidal High Density Lipoprotein Particles* (2004) (73)
- Contributions of the N- and C-terminal helical segments to the lipid-free structure and lipid interaction of apolipoprotein A-I. (2006) (72)
- Studies of synthetic peptides of human apolipoprotein A-I containing tandem amphipathic alpha-helixes. (1998) (70)
- Two-step Mechanism of Binding of Apolipoprotein E to Heparin (2005) (69)
- Apolipoprotein E;-low density lipoprotein receptor interaction. Influences of basic residue and amphipathic alpha-helix organization in the ligand. (2000) (69)
- The influence of apolipoprotein structure on the efflux of cellular free cholesterol to high density lipoprotein. (1994) (69)
- Complex and cluster formation in mixed lecithincholesterol bilayers. Cooperativity of motion in lipid systems (1971) (68)
- A quantitative analysis of apolipoprotein binding to SR-BI: multiple binding sites for lipid-free and lipid-associated apolipoproteins. (2003) (67)
- Remodeling and shuttling. Mechanisms for the synergistic effects between different acceptor particles in the mobilization of cellular cholesterol. (1997) (66)
- Lipid composition and physical state effects on cellular cholesteryl ester clearance. (1984) (66)
- Effect of cholesterol on the charge and structure of apolipoprotein A-I in recombinant high density lipoprotein particles. (1993) (66)
- Cholesterol transfer from small and large unilamellar vesicles. (1984) (65)
- Adsorption of apolipoprotein A-IV to phospholipid monolayers spread at the air/water interface. A model for its labile binding to high density lipoproteins. (1992) (64)
- Cellular cholesteryl ester clearance. Relationship to the physical state of cholesteryl ester inclusions. (1983) (64)
- Effects of lipid composition and packing on the adsorption of apolipoprotein A-I to lipid monolayers. (1988) (64)
- Macrophage Reverse Cholesterol Transport in Mice Expressing ApoA-I Milano (2009) (63)
- A 13C NMR characterization of lysine residues in apolipoprotein B and their role in binding to the low density lipoprotein receptor. (1988) (63)
- Multiple plasma membrane receptors but not NPC1L1 mediate high-affinity, ezetimibe-sensitive cholesterol uptake into the intestinal brush border membrane. (2007) (62)
- Role of apolipoproteins in cellular cholesterol efflux. (1986) (62)
- Identification of an Apolipoprotein A-I Structural Element That Mediates Cellular Cholesterol Efflux and Stabilizes ATP Binding Cassette Transporter A1* (2004) (60)
- Monolayer characteristics of 1,2-dimyristin, 1,2-dimyristoyl-3-cephalin and 1,2-dimyristoyl-3-lecithin at the air-water interface (1967) (58)
- Cholesterol desorption from clusters of phosphatidylcholine and cholesterol in unilamellar vesicle bilayers during lipid transfer or exchange. (1982) (57)
- The Conformation of Proteins at Interfaces and their Role in Stabilizing Emulsions (1976) (57)
- Molecular Interactions in Mixed Monolayers (1968) (57)
- Apolipoprotein A-I Structural Modification and the Functionality of Reconstituted High Density Lipoprotein Particles in Cellular Cholesterol Efflux* (1996) (57)
- Molecular mechanism of apolipoprotein E binding to lipoprotein particles. (2009) (57)
- Structures of aqueous dispersions of phosphatidylserine. (1973) (55)
- Conformational flexibility of the N-terminal domain of apolipoprotein a-I bound to spherical lipid particles. (2008) (53)
- The surface properties of apolipoproteins A-I and A-II at the lipid/water interface. (1989) (53)
- Molecular basis for the differences in lipid and lipoprotein binding properties of human apolipoproteins E3 and E4. (2010) (52)
- Influence of cholesterol on bilayers of ester- and ether-linked phospholipids. Permeability and 13C-nuclear magnetic resonance measurements. (1984) (51)
- Antimitogenic effects of HDL and APOE mediated by Cox-2-dependent IP activation. (2004) (50)
- Influence of tertiary structure domain properties on the functionality of apolipoprotein A-I. (2008) (50)
- Monolayer characteristic of some glycolipids at the air-water interface (1975) (50)
- Phase behavior of ether lipids from Clostridium butyricum. (1981) (50)
- Pathways by Which Reconstituted High-Density Lipoprotein Mobilizes Free Cholesterol From Whole Body and From Macrophages (2010) (50)
- Effects of membrane lipid composition on the kinetics of cholesterol exchange between lipoproteins and different species of red blood cells. (1990) (49)
- Molecular Mechanisms Responsible for the Differential Effects of ApoE3 and ApoE4 on Plasma Lipoprotein–Cholesterol Levels (2013) (49)
- Reference Parameters for Protein Hydrogen Exchange Rates (2018) (49)
- Wild-Type ApoA-I and the Milano Variant Have Similar Abilities to Stimulate Cellular Lipid Mobilization and Efflux (2007) (49)
- Effects of Enrichment of Fibroblasts with Unesterified Cholesterol on the Efflux of Cellular Lipids to Apolipoprotein A-I* (2002) (48)
- Contributions of the carboxyl-terminal helical segment to the self-association and lipoprotein preferences of human apolipoprotein E3 and E4 isoforms. (2008) (47)
- Apolipoprotein A-I-stimulated Apolipoprotein E Secretion from Human Macrophages Is Independent of Cholesterol Efflux* (2004) (46)
- [22] Studies of apolipoproteins at the air-water interface (1986) (45)
- A Consensus Model of Human Apolipoprotein A-I in its Monomeric and Lipid-free State (2017) (45)
- A comparison of the surface activities of human apolipoproteins A-I and A-II at the air/water interface. (1988) (45)
- Monolayers of some naturally occurring polycyclic compounds. (1967) (44)
- The conformation and aggregation of bovine β‐casein A. II. Thermodynamics of thermal association and the effects of changes in polar and apolar interactions on micellization (1979) (44)
- Role of the plasma membrane in the mechanism of cholesterol efflux from cells. (1984) (44)
- Influence of class B scavenger receptors on cholesterol flux across the brush border membrane and intestinal absorption (2009) (43)
- Interaction between the N- and C-terminal domains modulates the stability and lipid binding of apolipoprotein A-I. (2009) (43)
- ROLE OF LIPID AFFINITY AND MEMBRANE PENETRATION IN THE EFFLUX OF CELLULAR CHOLESTEROL AND PHOSPHOLIPID (1999) (42)
- Structure of human apolipoprotein A-IV: a distinct domain architecture among exchangeable apolipoproteins with potential functional implications. (2004) (41)
- Intestinal sterol absorption mediated by scavenger receptors is competitively inhibited by amphipathic peptides and proteins. (2000) (41)
- Influence of Apolipoprotein (Apo) A-I Structure on Nascent High Density Lipoprotein (HDL) Particle Size Distribution* (2010) (40)
- Effect of carboxyl-terminal truncation on structure and lipid interaction of human apolipoprotein E4. (2006) (40)
- Hydrolysis of lipid monolayers and the substrate specificity of hepatic lipase. (1986) (39)
- Effect of the Cholesterol Content of Reconstituted LpA-I on Lecithin:Cholesterol Acyltransferase Activity (*) (1995) (39)
- Interaction of class A amphipathic helical peptides with phospholipid unilamellar vesicles. (1997) (39)
- Influence of Apolipoprotein A-I Domain Structure on Macrophage Reverse Cholesterol Transport in Mice (2011) (39)
- CHAPTER 17 – Lipoprotein structure (2008) (39)
- Turnover of synthetic class A amphipathic peptide analogues of exchangeable apolipoproteins in rats. Correlation with physical properties. (1992) (38)
- Structural analysis of lipoprotein E particles. (2005) (37)
- PROPERTIES OF APOLIPOPROTEINS AT THE AIR‐WATER INTERFACE * (1980) (37)
- Physical Studies of Phospholipid/Alamethicin Interactions (1969) (37)
- Gel formation from solutions of single‐chain gelatin (1975) (37)
- Effect of vesicle size on their interaction with class A amphipathic helical peptides. (1997) (36)
- Robust passive and active efflux of cellular cholesterol to a designer functional mimic of high density lipoprotein (2015) (36)
- Dual Role of an N-terminal Amyloidogenic Mutation in Apolipoprotein A-I (2012) (36)
- Helical structure, stability, and dynamics in human apolipoprotein E3 and E4 by hydrogen exchange and mass spectrometry (2017) (35)
- Efflux of Newly Synthesized Cholesterol and Biosynthetic Sterol Intermediates from Cells (1995) (35)
- The roles of C-terminal helices of human apolipoprotein A-I in formation of high-density lipoprotein particles. (2014) (35)
- Mechanisms Responsible for the Compositional Heterogeneity of Nascent High Density Lipoprotein* (2013) (35)
- Conformation of apolipoprotein E in lipoproteins. (1993) (35)
- Surface plasmon resonance analysis of the mechanism of binding of apoA-I to high density lipoprotein particles (2010) (35)
- Comparison of apoA-I helical structure and stability in discoidal and spherical HDL particles by HX and mass spectrometry (2013) (33)
- 13C NMR evidence that substitution of glutamine for arginine 3500 in familial defective apolipoprotein B-100 disrupts the conformation of the receptor-binding domain. (1991) (33)
- Effects of polymorphism on the microenvironment of the LDL receptor-binding region of human apoE. (2001) (33)
- The miscibility of dipalmitoyl phosphatidylcholine and cholesterol in monolayers (1976) (33)
- Lipoproteins and cellular cholesterol homeostasis. (1997) (32)
- Influence of C-terminal α-helix hydrophobicity and aromatic amino acid content on apolipoprotein A-I functionality. (2012) (32)
- Interaction between the 35 kDa apolipoprotein of pulmonary surfactant and saturated phosphatidylcholines. Effects of temperature. (1986) (32)
- The contribution of α‐helices to the surface activities of proteins (1984) (32)
- Structure and properties of protein films adsorbed at the air-water interface (1975) (32)
- Effects of the Iowa and Milano mutations on apolipoprotein A-I structure and dynamics determined by hydrogen exchange and mass spectrometry. (2012) (31)
- Dietary modification of high density lipoprotein phospholipid and influence on cellular cholesterol efflux. (1998) (31)
- Factors controlling nascent high-density lipoprotein particle heterogeneity: ATP-binding cassette transporter A1 activity and cell lipid and apolipoprotein AI availability (2013) (31)
- Role of the N- and C-terminal domains in binding of apolipoprotein E isoforms to heparan sulfate and dermatan sulfate: a surface plasmon resonance study. (2008) (31)
- Physical studies of the interactions of acetylcholine chloride with membrane constituents. (1970) (29)
- Disruption of the C-terminal helix by single amino acid deletion is directly responsible for impaired cholesterol efflux ability of apolipoprotein A-I Nichinan (2010) (28)
- Mechanism of dissociation of human apolipoproteins A-I, A-11, and C from complexes with dimyristoylphosphatidylcholine as studied by thermal denaturation. (1984) (28)
- CRISPR/Cas9-Mediated Gene Editing in Human iPSC-Derived Macrophage Reveals Lysosomal Acid Lipase Function in Human Macrophages—Brief Report (2017) (28)
- The helical hydrophobic moments and surface activities of serum apolipoproteins. (1983) (27)
- Factors affecting molecular packing in mixed lipid monolayers and bilayers (1973) (27)
- Interaction of Proteins with Phospholipid Monolayers (1975) (26)
- Dipole interactions in monomolecular layers (1971) (26)
- Comparison of the intracellular metabolism and trafficking of 25-hydroxycholesterol and cholesterol in macrophages. (1996) (26)
- Interaction of thioflavin T with amyloid fibrils of apolipoprotein A-I N-terminal fragment: resonance energy transfer study. (2014) (25)
- Structural investigations of lipid, polypeptide and protein multilayers. (1973) (24)
- ATP-Binding Cassette Transporter A1 Deficiency in Human Induced Pluripotent Stem Cell-Derived Hepatocytes Abrogates HDL Biogenesis and Enhances Triglyceride Secretion (2017) (24)
- Fluorescence analysis of the lipid binding-induced conformational change of apolipoprotein E4. (2012) (24)
- Apolipoprotein E-mediated cell cycle arrest linked to p27 and the Cox2-dependent repression of miR221/222. (2013) (23)
- Influence of N-terminal helix bundle stability on the lipid-binding properties of human apolipoprotein A-I. (2011) (22)
- Effects of cholesterol and lipoproteins on endocytosis by a monocyte-like cell line. (1986) (22)
- The interaction of cholesterol with the sterol free lipids of plasma membranes. (1970) (22)
- Kinetic and thermodynamic analyses of spontaneous exchange between high-density lipoprotein-bound and lipid-free apolipoprotein A-I. (2015) (21)
- Effects of apolipoproteins on the kinetics of cholesterol exchange. (1991) (21)
- The uptake of cholesterol at the small‐intestinal brush border membrane is inhibited by apolipoproteins (1997) (21)
- Physical state of cholesteryl esters deposited in cultured macrophages. (1988) (20)
- Kinetics and mechanism of exchange of apolipoprotein C-III molecules from very low density lipoprotein particles. (1999) (20)
- Influence of Domain Stability on the Properties of Human Apolipoprotein E3 and E4 and Mouse Apolipoprotein E (2014) (20)
- Interactions of Apolipoprotein A-I with High-Density Lipoprotein Particles (2013) (20)
- Microenvironments of basic amino acids in amphipathic alpha-helices bound to phospholipid: 13C NMR studies using selectively labeled peptides. (1995) (20)
- A comparison of the surface activities of rat plasma apolipoproteins C-II, C-III-0, C-III-3. (1983) (19)
- Nuclear magnetic resonance investigation of the interactions with phospholipid of an amphipathic alpha-helix-forming peptide of the apolipoprotein class. (1990) (19)
- Protein hydrophobicity and lipid--protein interaction. (1973) (18)
- Mechanism of dissociation of human apolipoprotein A-I from complexes with dimyristoylphosphatidylcholine as studied by guanidine hydrochloride denaturation. (1982) (18)
- A comparison of the interfacial interactions of the apoprotein from high density lipoprotein and beta-casein with phospholipids. (1975) (18)
- Ion-binding to phospholipids. Interaction of calcium with phosphatidylserine. (1976) (18)
- Cholesterol efflux from arterial wall cells (1991) (18)
- Directional ABCA1-mediated cholesterol efflux and apoB-lipoprotein secretion in the retinal pigment epithelium (2018) (17)
- Lipid-protein interactions. Effect of apolipoprotein A-I on phosphatidylcholine polar group conformation as studied by proton nuclear magnetic resonance. (1982) (17)
- Cytoskeleton disruption in J774 macrophages: consequences for lipid droplet formation and cholesterol flux. (2012) (17)
- New insights into the determination of HDL structure by apolipoproteins1 (2013) (17)
- Studies of apolipoproteins at the air-water interface. (1986) (16)
- Novel In Vivo Method for Measuring Cholesterol Mass Flux in Peripheral Macrophages (2011) (16)
- Structure-function properties of the apoE-dependent COX-2 pathway in vascular smooth muscle cells. (2008) (15)
- Influence of the structure of the lipid-water interface on the activity of hepatic lipase. (1988) (15)
- Effect of substrate physical state on the activity of acid cholesteryl ester hydrolase. (1990) (14)
- Packing of cholesterol molecules in human high-density lipoproteins. (1984) (13)
- Effects of the core lipid on the energetics of binding of ApoA-I to model lipoprotein particles of different sizes. (2005) (12)
- Hydrophobic free energy and the denaturation of proteins. (1977) (12)
- Fluorescence study of domain structure and lipid interaction of human apolipoproteins E3 and E4. (2014) (12)
- Ageing resistance of bituminous road binders: benefits of SBS modification (1993) (12)
- Effects of apolipoprotein structure on the kinetics of apolipoprotein transfer between phospholipid vesicles. (1991) (12)
- Location and motion of free cholesterol molecules in high density lipoprotein. (1981) (11)
- Comparison of the effects of inorganic and organic (hydrophobic) cations on the physical states of proteins and phospholipid bilayer membranes (1977) (10)
- Monolayer characteristics of some glycolipids at the air-water interface. (1975) (10)
- Monolayers of block copolypeptides at the air—water interface (1979) (9)
- The conformation of apolipoprotein E isoforms in phospholipid complexes and their interaction with human Hep G2 cells. (1984) (9)
- Cholesterol efflux: mechanism and regulation. (1986) (9)
- Phase behavior of cholesteryl ester dispersions which model the inclusions of foam cells. (1990) (8)
- The aggregation of block copolypeptides in aqueous solution (1976) (8)
- Cholesterol packing, crystallization and exchange properties in phosphatidylcholine vesicle systems. (1990) (8)
- Effects of membrane lipids and -proteins and cytoskeletal proteins on the kinetics of cholesterol exchange between high density lipoprotein and human red blood cells, ghosts and microvesicles. (1992) (8)
- Kinetics and mechanism of transfer of reduced and carboxymethylated apolipoprotein A-II between phospholipid vesicles. (1990) (7)
- The phase behavior of cholesteryl esters in intracellular inclusions. (1992) (7)
- Interaction of apoprotein from porcine high-density lipoprotein with dimyristoly lecithin. 2. Nature of lipid-protein interaction. (1976) (6)
- Adsorption of lysozyme and some acetyl derivatives at the air-water interface (2007) (5)
- The interaction of ions with phosphatidylcholine. (1977) (5)
- Effects of amino acid substitutions at glycine 420 on SR-BI cholesterol transport function Published, JLR Papers in Press, March 19, 2007. (2007) (5)
- Cell lipid metabolism modulators 2-bromopalmitate, D609, monensin, U18666A and probucol shift discoidal HDL formation to the smaller-sized particles: implications for the mechanism of HDL assembly. (2016) (4)
- A quantitative analysis of apolipoprotein binding to SR-BI Published, JLR Papers in Press, April 1, 2003. DOI 10.1194/jlr.M200429-JLR200 (2003) (3)
- Influence of apolipoprotein A-I and apolipoprotein A-II availability on nascent HDL heterogeneity (2013) (3)
- The contribution of alpha-helices to the surface activities of proteins. (1984) (2)
- 1.P.15 Distinct apo B-100 conformation and surface charge are major determinants of the elevated atherogenicity of small-dense low density lipoprotein particles (1997) (2)
- Contemporary Reviews in Cardiovascular Medicine Cholesterol Efflux and Atheroprotection Advancing the Concept of Reverse Cholesterol Transport (2012) (2)
- New HIV drugs in development, 2005 (2005) (1)
- Abstract 17314: Free Radical-Dependent Sod2 Promoter Demethylation is Associated with Healthy Vascular Aging (2011) (1)
- ApoC-III helical structure determines its ability to bind plasma lipoproteins and inhibit Lipoprotein Lipase-mediated triglyceride lipolysis (2020) (1)
- 4.P.340 Apolipoprotein A-I-mediated cell cholesterol efflux (1997) (1)
- P1 Niacin Inhibits Chain ATP Synthase Cell Surface Expression in HepG2 Cells: Mechanistic Implications for Raising HDL (2010) (1)
- Effect of lipid composition and packing on the adsorption of apolipoproteins to lipid monolayers (1987) (1)
- 3P-0724 Domain structure and lipid interaction in human apolipoprotein A-I (2003) (1)
- Cholesterol Efflux from Cells in Culture: Studies with Lipid-Free Acceptors, Reconstituted Particles and Whole Serum (1995) (0)
- 4.P.339 NEM-sensitive factor influences the distribution of cholesterol within the plasma membrane of cells (1997) (0)
- 1P-0232 Apolipoprotein A-I-mediated secretion of apolipoprotein E has structural requirements distinct from those related to stimulation of cholesterol efflux (2003) (0)
- Abstract 332: Coronary Artery Disease-Protective Variant A43T in APOC3 Alters Circulating ApoC-III Levels In vivo (2015) (0)
- Effects of apoe polymorphism on its stability and interactions with lipids (2000) (0)
- Atherosclerosis Atherosclerosis in Dyslipidemic Obese Mice : LCAT Gene Transfer Decreases Antioxidant Defense Are Associated With Increased Macrophage Homing and Increased Low-Density Lipoprotein Oxidation and Impaired High-Density Lipoprotein (2003) (0)
- Mechanisms of cholesterol movement between high density lipoproteins (HDL) and cells (2000) (0)
- Interaction of serum apolipoproteins with scavenger receptor (SR)-BI (2000) (0)
- Preparation of Oriented Cellular Membranes for X-Ray Diffraction Analysis (1999) (0)
- 3.P.164 Cytotoxic responses to free cholesterol accumulation in the macrophage foam cell are blocked by the cholesterol transport inhibitor U18666A (1997) (0)
- Reference Parameters for Protein Hydrogen Exchange Rates. (2018) (0)
- Role of ABCA 1 in Cellular Cholesterol Efflux and Reverse Cholesterol Transport Series (2003) (0)
- In Memoriam: Julian B. Marsh (1926–2018) (2019) (0)
- Tu-W23:5 Intravenous administration of large unilamellar vesicles and Apo AI/Phospholipid complexes increases free cholesterol in plasma by different mechanism (2006) (0)
- Contributions of the N- and C-terminal helical segments to the lipid-free structure and lipid interaction of human apolipoprotein A-I (2007) (0)
- The Physico-Chemical Properties of Lipids in Lipoproteins (1978) (0)
- Effects of voluntary exercise on epigenetic regulation and vascular properties in a model of dyslipidemia (2011) (0)
- Synthetic peptides from putative amphipathic β strand sequences of apolipoprotein B-100 associate with lipid in the β strand conformation (2002) (0)
- Roles of the N-terminal segment on lipid interaction of apolipoprotein A-I (2006) (0)
- LACK OF RELATIONSHIP TO SPECIFIC BINDING OF THE LIPOPROTEIN TO THE CELL (2001) (0)
- Abstract 329: CRISPR/Cas-mediated Gene Editing in Human iPSC-derived Macrophage Reveals Lysosomal Acid Lipase Functions in Human Macrophages (2015) (0)
- 2.W17.4 HDL and cellular cholesterol efflux (1997) (0)
- Closing Comments and Summary (1984) (0)
- Interfacial basic amino acids increase the lipid affinity of class A amphipathic helix: Evidence for snorkel hypothesis by 13C-NMR spectroscopy (1994) (0)
- 3.P.145 The use of cyclodextrin: Cholesterol complexes to study cholesterol transport in macrophages and other foam cell models (1997) (0)
- Thermodynamic analysis of apolipoprotein-lipid interaction (2005) (0)
- The Membranes of Cells (1994) (0)
- The Arg123-Tyr166 central domain of human ApoAI is critical for HDL mediated inhibition of macrophage homing and early atherosclerosis in ApoE knockout mice independent of cholesterol efflux (2001) (0)
- 10 Molecular mechanisms of reverse cholesterol transport (1997) (0)
- ATVB In Focus Role of ABCA1 in Cellular Cholesterol Efflux and Reverse Cholesterol Transport (2003) (0)
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